KR20220100294A - Device for oral drug delivery using a drug bag - Google Patents

Abstract

The present invention relates to an intraoral drug delivery device capable of slowly delivering drugs for a predetermined duration which comprises: a drug bag consisting of a bag-type to store drugs therein and introducing saliva therein so that the drugs dissolved by saliva can be slowly discharged into the oral cavity; and a connecting string having both ends fixed to the drug bag and fixing the drug bag in the oral cavity by winding or hanging around teeth in the oral cavity. In addition, the intraoral drug delivery device is configured so that the drugs can be gradually delivered into the oral cavity by fixing the drug bag to teeth, mouthpieces, braces, and the like in the oral cavity using the connecting string.

Description

Intraoral drug delivery device using a drug bag {Device for oral drug delivery using a drug bag}

The present invention relates to an oral drug delivery device. More particularly, the present invention relates to an intraoral drug delivery device using a drug bag in which a drug is stored in the drug bag and fixed in the mouth, so that the drug is slowly released and delivered in the oral cavity.

In general, the drug supplied to obtain an effect by acting on the tissues in the oral cavity is prepared in the form of an ointment or liquid, and is applied directly to the user's teeth or gums, or a method of spraying it into the oral cavity using a supply device such as a spray Or it has been used as a method of spitting out after brushing for a certain period of time.

However, since the inside of a person's oral cavity is always wet with saliva, even if an ointment or liquid drug is applied, it is diluted or washed away by saliva within a short period of time.

Therefore, there is a disadvantage in that it is necessary to periodically apply or spray the drug in order to treat the drug for a long time, which causes a lot of inconvenience. In addition, since it is practically impossible to supply the drug at the correct time during daily life, there is a problem in that it is difficult to expect high drug efficacy. In addition, since oral drugs are swallowed together with water, preparation or application of drugs that need to be absorbed and absorbed in the oral cavity is limited.

In order to solve this problem, a method has been proposed in which a drug is manufactured in the form of candy or gum so that the patient can hold it in the mouth for a long time. It is easily swallowed, so it has the disadvantage of low reliability.

In consideration of the above problems, as a prior art, a continuous drug delivery device through the mouth has been proposed in Korean Patent Application Laid-Open No. 10-2016-0084422. It comprises a fastener for removably securing the drug delivery device to the surface of the patient's mouth, an electrical or mechanical pump, and a pharmaceutical composition comprising levodopa or a levodopa prodrug, having a volume of 01 mL to 5 mL, as a suspension or A drug for continuous or semi-continuous intraoral administration of a pharmaceutical composition comprising the drug and configured to be removably inserted into the mouth of a patient comprising an oral liquid impermeable drug reservoir comprising as a solid and an automatic stop/start portion A delivery device has been proposed.

The prior art as described above includes a retainer that attaches the fastener to the teeth, and a drug storage unit having an electrical and mechanical pump on the fastener is installed to be detachably attached to one side of the fastener. The drug injected into the drug storage unit is continuously supplied by a pump and the drug is transported from the side of the tooth to the lingual side through the tube.

However, there is a problem in that the foreign body feeling is too large in terms of volume or structure because it is necessary to couple the drug storage unit having an electrical or mechanical pump to the fastener coupled in the mouth.

Korean Patent Application Laid-Open No. 10-2016-0084422 (Title of the invention: continuous drug delivery device through the mouth) (published on July 13, 2016)

It is an object of the present invention to provide an intraoral drug delivery device capable of slowly delivering a drug in the oral cavity by putting a drug in a drug bag and fixing it in the mouth.

Another object of the present invention is to allow the drug delivery duration to be easily set by varying the type of drug bag or the dose of the drug to be injected.

An oral drug delivery device according to an embodiment for achieving the object of the present invention,

a drug bag made of a bag type, in which the drug is accommodated, and the saliva flows into the drug bag so that the drug melted by the saliva can be gradually discharged into the oral cavity;

a connection string having both ends fixed to the drug bag and wound or hung around the teeth in the oral cavity to fix the drug bag in the oral cavity;

an adjustment member that is slidably fitted to the connecting string and fastens the connecting string wound around the teeth or inserted into the tooth gap to fix the drug bag to the teeth; and

a stopper fixed to the connecting string at the rear end of the adjusting member to prevent separation of the adjusting member; includes

In addition, the oral drug delivery device according to another embodiment of the present invention,

a mouthpiece coupled to the teeth;

a drug bag made of a bag type, in which the drug is accommodated, and the saliva flows into the drug bag so that the drug melted by the saliva can be gradually discharged to the outside;

a connection string having both ends fixed to the drug bag, and winding or hanging around the mouth piece to fix the drug bag to the mouth piece; includes

At least one trench groove may be formed in the mouthpiece, and the drug bag may be fixed by hanging the connection string in the trench groove.

In another embodiment, the oral drug delivery device comprises:

a mouthpiece coupled to the teeth;

a drug bag made of a bag type, in which the drug is accommodated, and the saliva flows into the drug bag so that the drug melted by the saliva can be gradually discharged to the outside;

and an attachment rack made of a Velcro band adhesively fixed to the outer surface of the mouthpiece, and configured to directly attach the drug bag to the Velcro band.

Or, a long portion is formed on one side of the mouthpiece,

A column having a length greater than or equal to the thickness of one side of the mouthpiece is formed on the base portion, and a hook portion passing through the elongated portion is formed at the tip of the column portion, further comprising a detachable hook member fitted and fixed in the elongated portion,

The drag bag may be fixed to the mouthpiece by hooking the connecting string to the hook portion of the hook member.

In addition, both the base part and the hook part may be formed in a bar type, and the hook member may be mounted to the mouthpiece by rotating the hook part through the long part from the inside of one side of the mouthpiece.

In addition, a protruding ring or an inner ring may be formed on one side of the mouthpiece, and the drug bag may be fixed to the mouthpiece by hanging the connecting string of the drug bag on the ring.

The mouthpiece may be composed of an integral mouthpiece integrally coupled to the left and right teeth and the front teeth, or a partial mouthpiece coupled to two or three incisors, left teeth or right teeth.

Alternatively, instead of a mouthpiece enclosing the teeth, it may be composed of a border-type mouth band having elasticity that is inserted and fixed to the outer or inner portion of the tooth.

The drug bag,

It is characterized in that it uses an eco-friendly nonwoven material, and fixes both ends of the connection string at two adjacent corner points, and is manufactured in any one shape of a rectangle, a circle, and an oval.

As a method of adjusting the drug delivery release type of the drug bag,

A method of adjusting the drug release time by adjusting the weaving density of the fibers constituting the drug bag

A method in which one side of the textile material constituting the drug bag is coated to prevent moisture penetration, so that only the other side is used to penetrate the saliva and discharge the drug dissolved in the saliva;

A method of adjusting the drug time release by forming a multi-layered structure of the fibrous material constituting the drug bag and filling the drug between each layer;

A method of adjusting the drug time release by forming a number of holes in the fiber material constituting the drug bag for the penetration of saliva and the discharge of the drug dissolved in the saliva, depending on the size of the hole, the number of holes, and the arrangement direction of the holes

Allows the drug release time to be adjusted through any one or more of these methods.

The present invention can provide an oral drug delivery device in which the drug is inserted into the oral cavity by inserting and fixing the drug in a drug bag, whereby the drug is dissolved in saliva and gradually delivered into the oral cavity. Accordingly, if the drug is to be taken slowly for a long time or to be delivered into the oral cavity, the drug is put in a drug bag and fixed in the mouth.

The present invention is a method of fixing a drug bag containing a drug in the mouth, directly fixing the connection string by tilting it between teeth and tightening it using an adjustment member, and fixing the connection string of the drug bag to the mouthpiece by providing a mouthpiece It can be fixed in the mouth in such a way as to prevent swallowing.

In addition, by storing the drug in the drug bag and inserting it into the oral cavity, the fiber density of the drug bag, multi-layer structure, prevention of moisture penetration on one side, a method of forming a plurality of holes, a method of controlling the size or number of holes, etc. It has the effect of being able to easily adjust the drag release time using

1 (A) and (B) are views for explaining the configuration and use examples of the drug bag stand-alone oral drug delivery device according to the present invention.
2 (A) to (D) are diagrams illustrating the configuration of a drug bag for intraoral drug delivery according to the present invention.
3 (A) to (C) are explanatory views for fixing the drug bag for intraoral drug delivery according to the present invention in the oral cavity.
4 (A) to (C) are diagrams illustrating the configuration and use of a composite intraoral drug delivery device using a mouthpiece and a drug bag according to another embodiment of the present invention.
5 (A) and (B) are configuration explanatory views for fixing the drug bag by forming a trench groove in the mouthpiece.
6 is an explanatory view of a partial mouthpiece for fixing the drug bag of the present invention and a protruding hook formed on the mouthpiece to fix the drug bag.
7 (A) and (B) are explanatory views for fixing the drug bag by forming a partial mouthpiece for incisors for fixing the drug bag and internal hooks on the mouth piece.
8 (A) and (B) are configuration explanatory views for fixing the drug bag by coupling the removable hook member to the mouthpiece.

The following is merely illustrative of the principles of the invention. Therefore, those skilled in the art will be able to devise various devices and methods that, although not explicitly described or shown herein, embody the principles of the present invention and are included within the spirit and scope of the present invention. In addition, it should be understood that all conditional terms and examples listed herein are, in principle, expressly intended only for the purpose of understanding the inventive concept, and are not limited to the specifically enumerated embodiments and states as such. do.

Moreover, it is to be understood that all detailed description reciting specific embodiments, as well as principles, aspects, and embodiments of the present invention, are intended to include structural and functional equivalents thereof. It is also to be understood that such equivalents include not only currently known equivalents, but also equivalents developed in the future, i.e., all devices invented to perform the same function, regardless of structure.

The above-described objects, features and advantages will become more apparent through the following detailed description in relation to the accompanying drawings, and accordingly, those of ordinary skill in the art to which the present invention pertains can easily implement the technical idea of the present invention. There will be. In addition, when it is determined that the detailed description of the known technology related to the present invention may unnecessarily obscure the gist of the present invention in carrying out the present invention, the detailed description thereof will be omitted.

The terms used in the present application are only used to describe specific embodiments, and are not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly dictates otherwise. In the present application, terms such as “comprise” or “have” are intended to designate that a feature, number, step, operation, component, part, or combination thereof described in the specification exists, but one or more other features It is to be understood that this does not preclude the possibility of the presence or addition of numbers, steps, operations, components, parts, or combinations thereof.

Hereinafter, preferred embodiments of the present invention will be described in more detail with reference to the accompanying drawings. In describing the present invention, in order to facilitate the overall understanding, the same reference numerals are used for the same components in the drawings, and duplicate descriptions of the same components are omitted.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 (A) and (B) are diagrams for explaining the configuration and use examples of the drug bag stand-alone intraoral drug delivery device according to the present invention.

a drug bag 10 made of a bag type, the drug is accommodated therein, and the saliva is introduced into the interior so that the drug melted by the saliva can be gradually discharged into the oral cavity; a connection string 20 having both ends fixed to the drug bag 10, wound around the teeth in the oral cavity or hanging to fix the drug bag 10 in the oral cavity; an adjustment member 30 that is slidably fitted to the connecting string 20 and fastens the connecting string 20 that is wound around the teeth or inserted into the tooth gap to fix the drug bag 10 to the teeth; and a stopper 40 fixed to the rear end connection string 20 of the adjustment member 30 to prevent the adjustment member 30 from being separated; includes

In the single drug bag type intraoral drug delivery device according to the present invention, the drug 100 is accommodated in the drug bag 10, and the drug bag 10 is inserted into the mouth and fixed. Accordingly, the saliva penetrates into the drug bag to dissolve the drug, and the drug dissolved in the saliva is discharged into the oral cavity to realize drug delivery. This drug delivery method can be usefully used when it is necessary to slowly deliver a drug for a long time.

The existing intraoral drug delivery device uses a mechanical structure to attach a bracket to the teeth so that the solidified drug is directly in contact with the saliva to melt and deliver it, or by installing a drug dispenser to continuously administer the drug into the mouth. Because it is complicated and difficult to use by general users, only professional medical personnel can fix the drug delivery device in the oral cavity and use it as a drug delivery device.

On the other hand, the oral drug delivery device using the drug bag of the present invention inserts the drug into the drug bag and uses the connecting string 20 to directly fix the difference 1, so anyone can use it easily. There is an advantage that

As a method for fixing the drug bag 10 to the tooth 1, it can be used as a method of winding and tying the tooth 1 using the connecting string 20 with the middle part separated. A method of lodging the connection string 20 in the mouth may be inconvenient. Accordingly, in the present invention, the connecting string 20 is formed in a ring shape, and the adjusting member 30 is inserted into the annular connecting string 20 and tightened using the adjusting member 30 to fix the drug bag 10 to the teeth. use the method

As shown in Fig. 1 (b), the two lines of the connecting string 20 are separated and inserted into the gap between the teeth and the teeth so that the teeth 1 are positioned between the adjustment member 20 and the drug bag 10, and adjusted. A method of fixing the drug bag 10 to the teeth by tightening the member 30 may be used.

Here, the adjustment member 30 and the stopper 40 are not necessarily required, and a method of winding the tooth through the connecting muscle 20 or passing it through the tooth gap and tightening it from the outside with a knot may be used.

In addition, the adjustment member 30 is an example formed with two holes through which two lines pass, but is not limited thereto, and the connection string 20 is fixed at a stopped position after two lines pass through one hole and slide. It is also possible to configure the same structure as a normal string length adjustment member that can be.

The adjusting member 30 is to be put in the mouth to adjust the length of the connecting string 20 to fix the drug bag 10, so it should be made of a material that is not harmful. For example, it may be implemented by forming a narrow hole in the adjustment member 20 made of silicon material permitted for human use and configuring it to slide only when force is applied.

2 (A) to (D) are diagrams illustrating the configuration of a drug bag for intraoral drug delivery according to the present invention.

As shown in FIG. 2(A), the basic type of the drug bag is to accommodate the drug 100 of a preset dose to be injected into the oral cavity between the upper and lower drug bag materials 11 and adhere or sew the edges to form one drug bag ( 10) can be configured.

In the drug bag manufacturing method, the drug itself is placed on one side of the drug bag material in an appropriate dose, or an appropriate dose is arranged/applied by screen printing of a gel-type drug, or printed with multiple drug points and dried to solidify. It may be manufactured in such a way that the edge is sealed by covering the other member.

Figure 2 (b) shows that the member on either side of the upper and lower members constituting the drug bag uses the moisture permeation prevention coating member 12, and the member on the other side of the corresponding side uses the penetration of saliva and the drug dissolved in the saliva is discharged. The member 11 may be configured to have a structure in which the penetration of saliva and the drug dissolved in the saliva are discharged only on one side. As compared to FIG. 2(A), in which the penetration of saliva is possible on both sides, saliva penetration and drug discharge are possible only on one side.

In addition, (c) of FIG. 2 is a structure in which the drug bag material 11 is formed in a multi-layered structure when different drugs 100 and 101 are to be delivered together, and each drug is accommodated between each member. to be. This is a structure that can deliver different drugs into the oral cavity at the same time by separately storing two or more drugs by configuring the drug bag 10 in a multi-layer structure when different drugs need to be administered at the same time.

In addition, (d) of Figure 2 is configured to adjust the drug delivery time by configuring the upper and lower members as a multi-layer member 13, that is, by varying the thickness of the upper and lower members or having a multilayer structure.

The drug bag material 11 should be able to penetrate the saliva, and the drug dissolved in the saliva should be able to be discharged. must be sealed.

In addition, it is most preferable to have a configuration in which the drug bag material 11 does not absorb moisture, but the saliva flows into the gap between the threads to dissolve the drug and the drug dissolved in the saliva can be discharged. This is because when the drug is dissolved and absorbed into the drug bag material 11, the amount of drug delivered into the oral cavity is reduced. .

In order to improve this problem, when a fiber material such as a nonwoven fabric is used, the fiber material is pre-coated to prevent moisture absorption, but by adjusting the weaving interval of the fiber material, saliva flows in and the drug dissolved in the saliva is discharged. It is preferable to weave or perforate to have a porous structure that can be used. In addition, the upper and lower members 11 may be formed using a thin film silicone member or vinyls harmless to the human body, and porous holes may be formed in the upper and lower members.

As described above, as the material constituting the drug bag of the present invention, a number of small holes are arranged in a thin film silicon material and a fiber material such as a nonwoven fabric for easy penetration of saliva and discharge of a drug dissolved in saliva, and the needle passes through the hole. It is also possible to use a resin material or the like produced so that the inflow and the drug dissolved in saliva can be discharged.

In addition, the drug bag 10 should be packaged and stored by a packaging material, and can be used by removing the packaging material during use.

Since the oral drug delivery device to be provided by the present invention has the purpose of continuously delivering a drug into the oral cavity for a long time, a method of adjusting the drug release time for this is required.

The drug bag of the present invention can adjust the overall size or adjust the drug delivery duration and drug input dose to adjust the drug dose to be accommodated. In addition to this, as a method of adjusting the drug delivery release type of the drug bag,

a). A method of adjusting the drug release time by adjusting the weaving density of the fibers constituting the drug bag,

b). A method in which one side of the textile material constituting the drug bag is coated to prevent moisture penetration, so that only the other side is used to penetrate the saliva and discharge the drug dissolved in the saliva;

c). A method of adjusting the drug time release by forming a multi-layered structure of the fibrous material constituting the drug bag and filling the drug between each layer;

d). Any one of the method of adjusting the drug time release according to the size of the hole, the number of holes, and the arrangement direction of the holes by forming a plurality of holes in the material constituting the drug bag for the penetration of saliva and the discharge of the drug dissolved in the saliva Alternatively, it allows you to adjust the drug release time in a complex way.

In addition to the release time adjustment method exemplified above, a method of mixing a mixture with the drug itself so that the time the drug dissolves in saliva can be adjusted, or a shape for accommodating the drug, for example, a method of forming a drug in one lump, applying thinly method, a method of forming a multi-arranged drug dome, etc., a method of adjusting the dissolution time of the drug in saliva, a method of adjusting the release time using a drug bag structure, a method of changing the position of fixation in the oral cavity, etc. You can adjust the release time.

3 (A) to (C) are explanatory views of fixing the drug bag for intraoral drug delivery according to the present invention in the oral cavity.

The drug bag 10 of the present invention can be fixed directly to the tooth 1 by fixing the connection string 20 and using the connection string 20 . Here, both ends of the connection string 20 are separated and fixed in two places in the drug bag 10 . This is to enable the other end of the connecting string 20 to be fixed to the drug bag even if either side is broken or separated. The connecting string 20 may use a thin thread, such as dental floss, but not easily broken.

As shown in Fig. 3 (A), the connection string 20 between the drug bag 10 and the adjustment member 30 in the gap of the tooth 1, that is, the thread is inserted into the gap on both sides of the tooth, and in Fig. 3 (B) Pull the end knot of the connecting string 20 as shown so that the drug bag 10 is close to the teeth and adjusted to a position with less foreign body feeling in the mouth. Thereafter, as shown in (c) of FIG. 3 , the adjustment member 30 is moved to the tooth side to fix the drug bag 10 to the tooth.

Here, the connecting string 20 is a ring-shaped example, and when the adjusting member 30 is installed, it may be configured in a configuration in which a knot or a stopper 40 is formed at the rear end, but is not limited thereto, and the connecting string is not limited thereto. (20) may be formed as a short-length loop, or a long-length yarn separated into two strands may be used. In the case of having two separate threads, after adjusting the position of the drug bag 10 as shown in FIG.

4 (A) to (C) are diagrams illustrating the configuration and use of a composite intraoral drug delivery device using a mouthpiece and a drug bag according to another embodiment of the present invention.

According to the present invention, there is provided an intraoral drug delivery device of a drug bag fixing method using a mouthpiece, comprising: a mouthpiece 50 coupled to a tooth; a drug bag 10 made of a bag type, the drug is accommodated therein, and the saliva flows into the drug so that the drug melted by the saliva can be gradually discharged to the outside; and a connection string 20 having both ends fixed to the drug bag 10 and winding or hanging around the mouth piece 50 to fix the drug bag 10 to the mouth piece 50 .

3 (A) to (C) in which the drug bag 10 is fixed in the mouth by directly inserting it into the tooth gap using the connecting string 20 can be used, but in this case, it is inserted between the teeth. Since the thread has to be stitched, it is difficult to fix it in a part without a gap between the teeth, and there is a risk of swallowing it as it is easily detached.

In order to improve this problem, as shown in FIG. 4(A), a mouthpiece 50 fitted to the tooth is provided, and the connection string 20 of the drug bag 10 is wound or hung on the mouthpiece 50 and the tooth way to put it in. As shown in Fig. 4 (b), the connection string 20 of the drug bag 10 is wound around the inner and outer circumferences of the mouthpiece 10 and the mouthpiece 50 is inserted into the tooth 1, and the mouthpiece (50) can be used to fix the drug bag (10) in the mouth. A mouthpiece for a drug delivery device may be made exclusively, but the present invention is not limited thereto, and a mouthpiece for orthodontic braces fitted to most of the teeth, a dental brace or a mouthpiece for protecting teeth, a mouthpiece for preventing snoring, etc. Mouth fixed in the mouth Pieces are available. As shown in (c) of FIG. 4 , depending on the type of the mouthpiece, the connection string 20 may be wound around the mouthpiece 50 or the drug bag 10 may be fixed by hanging.

5 (A) and (B) are configuration explanatory views for fixing the drug bag by forming a trench groove in the mouthpiece.

In the case of using the mouthpiece 50, at least one trench groove 51 is formed in the mouthpiece 50 as shown in FIG. 5, and the connection string 20 is hung in the trench groove 51 to hang the drug The bag 10 can be fixed. Since the connection string 20 is wound by using the trench groove 51 at an angle, the thread does not come into contact with the gum in contact with the side surface of the mouthpiece, thereby reducing the feeling of foreign body and has the advantage of not being easily separated.

In addition, although not shown in the drawings, it includes an attachment rack formed on the drug bag so as to have a Velcro band adhesively fixed to the outer surface of the mouthpiece 50, and to directly attach the drug bag to the Velcro band. can be configured. However, in this case, it is preferable to adjust the position and size so that the Velcro band can be reliably covered by the drag bag because the Velcro band attached to the mouthpiece can greatly blow a foreign feeling.

On the other hand, as the mouthpiece in the drug delivery device of the present invention, a mouthpiece that covers most of the teeth may be used, but a partial mouthpiece that covers only 2-3 teeth may be used. As a partial mouthpiece, as shown in FIG. 6, a partial mouthpiece for a side fitted to a molar or lateral tooth, or a partial mouthpiece for an incisor fitted to an incisor as shown in FIG. 7(a) can be used. Here, for convenience, the same reference numeral 50 is assigned to both the partial mouthpiece for the side and front teeth and the integral mouthpiece.

Even when using the partial mouthpiece as described above, the method of fixing the drug bag by winding a connecting ring around the cross-section of the mouthpiece as shown in FIG. 4, or forming a trench groove as shown in FIG. 5 and connecting through the trench groove You can use any method of fixing the drag bag by winding a string.

On the other hand, the partial mouthpiece 50 for incisors as shown in FIG. 7, although not shown in the drawings, may be used as a mouthpiece for protecting the incisors because the sidewall on the side of the bar has a thicker thickness than the sidewall on the inner side. In addition, a character or picture is formed on the outer front so that the character or picture displayed on the mouthpiece can be seen when the partial mouthpiece for front teeth is worn, so that it can look good or give a feeling of fun while wearing the partial mouthpiece. can

6 is an explanatory view of a partial mouthpiece for fixing the drug bag of the present invention and a protruding hook formed on the mouthpiece to fix the drug bag.

6, a protruding hook 53 is formed on one side of the mouthpiece 50, and the connecting string 20 of the drug bag 10 is wound or hung around the protruding hook 53. A method of fixing the bag (10). 6 exemplifies the side mouthpiece, but is not limited thereto, and the same is applied to the entire mouthpiece of FIG. 1 or the mouthpiece for the front teeth of FIG. 7 to form a protruding hook to fix the drug bag.

In addition, although not shown in the drawings, in addition to the tooth-covering type mouthpiece, a deformable edging mouthpiece having a rim portion in contact with the inner or outer surface of the tooth and a hook portion fixed to the incisor by hooking it, or an incisor Even when using a mouthpiece for preventing bruising having a hook edge and a molar cover, the drug bag can be fixed by hanging or winding the connecting string as described above.

7 (A) and (B) are explanatory views for fixing the drug bag by forming a partial mouthpiece for incisors for fixing the drug bag and internal hooks on the mouth piece. As shown in FIG. 7 , as a partial mouthpiece, the drug bag 10 can be fixed by configuring a partial mouthpiece for incisors that covers 2-3 incisors. A "T"-shaped through-groove 55a is formed on the side wall of the mouthpiece as shown in (A) and (B) of FIG. 7 in a manner to fix the drug bag 10, but the "T"-shaped through groove 55a protrudes from the through groove 55a. It is constituted by forming a T"-shaped inner hook 55. The drug bag 10 can be fixed by hanging or winding the connecting ring 20 on the inner hook 55 configured as described above. Of course, the inner hook 55 as shown in (A) and (B) of FIG. 7 may be equally applied to the integral mouthpiece of FIG. 1 or the partial mouthpiece for the side of FIG. 6 to fix the drug bag.

8 (A) and (B) are configuration explanatory views for fixing the drug bag by coupling the removable hook member to the mouthpiece. As shown in FIG. 8, a long portion 56 is formed on one wall of the mouthpiece, and a detachable hook member 54 with upper and lower bars formed at the upper and lower ends of the column so that either bar can be inserted into the long portion 56 and rotated. ) is provided. As shown in (B) of FIG. 8 , either bar of the hook member 54 is inserted into the long part 56 of the mouthpiece 50 horizontally and then rotated at a right angle to fix it so as not to fall out, and the hook exposed to the outside This is a method of fixing the drug bag 10 by hanging the connecting string 20 on the bar. This can be implemented in a detachable manner, so that the length of the connecting string 20 is shortened and the length is adjusted in advance, and in a state where the drug bag is fixed by hanging the connecting string on the hook member, the hook member is attached to the mouthpiece The drug bag can be fixed to the mouthpiece by inserting it into the long part of the mouthpiece and rotating it.

In the above, preferred embodiments of the present invention have been illustrated and described, but the present invention is not limited to the specific embodiments described above, and it is common in the technical field to which the present invention pertains without departing from the gist of the present invention as claimed in the claims. Various modifications may be made by those having the knowledge of, of course, and these modifications should not be individually understood from the technical spirit or perspective of the present invention.

10: drug bag 11, 12, 13: drug bag material
20: connection string 30: adjustment member
40: stopper (knot) 50: mouthpiece
51: trench groove 53: protruding hook
54: removable hook member 55: internal hook
56: intestinal tract 100: drug

Claims (10)

In the oral drug delivery device,
a drug bag made of a bag type, in which the drug is accommodated, and the saliva flows into the drug bag so that the drug melted by the saliva can be gradually discharged into the oral cavity;
Both ends are fixed to the drug bag, including a connection string for fixing the drug bag in the oral cavity by winding or walking on the teeth in the oral cavity
An oral drug delivery device using a drug bag.
The method of claim 1,
Further comprising an adjustment member that is slidably fitted to the connection string, and tightens the connection string wound around the teeth or fitted into the tooth gap to fix the drug bag to the teeth
An oral drug delivery device using a drug bag.
The method of claim 1,
Further comprising a mouthpiece for engaging the teeth,
Winding or hanging the connecting string having both ends fixed to the drug bag on the mouthpiece to fix the drug bag to the mouthpiece worn on the teeth
An oral drug delivery device using a drug bag.
4. The method of claim 3,
The mouth piece is any one of a lower tooth or an integral mouth piece coupled to the lower tooth, a partial mouth piece for the side covering only 2-3 teeth, and a partial mouth piece for incisors
An oral drug delivery device using a drug bag.
4. The method of claim 3,
At least one trench groove is formed in the side wall of the mouthpiece, and the drug bag is fixed by hanging the connecting string in the trench groove.
An oral drug delivery device using a drug bag.
4. The method of claim 3,
A protruding hook or a through groove is formed on one wall of the mouthpiece to form an inner hook formed in the through groove, and the drug bag is fixed to the mouthpiece by hanging the connecting string of the drug bag on the hook.
An oral drug delivery device using a drug bag.
4. The method of claim 3,
A long part penetrating through one side wall of the mouthpiece is formed,
and a detachable hook member having upper and lower bars formed at the upper and lower ends of the column part,
One side bar of the detachable hook member is inserted through the long part and rotated to couple the removable hook member to the long part of the mouthpiece, and the connecting string of the drug bag is hung on the hook member to fix the drug bag to the mouthpiece
An oral drug delivery device using a drug bag.
4. The method of claim 3,
The mouthpiece is
Any one of a edging mouthpiece having a deformable structure having a rim in contact with the inner or lateral surface of the tooth and a hook fixed to the front teeth by hooking it, or an anti-brushing mouthpiece having an incisor hook rim and a molar cover.
An oral drug delivery device using a drug bag.
The method of claim 1,
The drug bag,
It uses an eco-friendly non-woven fabric material, fixes both ends of the connecting string at two adjacent corner points, and is manufactured in any one shape of a rectangle, a circle, and an oval.
An oral drug delivery device using a drug bag.
The method of claim 1,
The drug bag,
a). A method of adjusting the drug release time by adjusting the weaving density of the fibers constituting the drug bag,
b). A method in which one side of the fiber material constituting the drug bag is coated with a coating to prevent moisture penetration, so that the penetration of saliva and the discharge of the drug dissolved in the saliva are made only through the other side;
c). A method of adjusting the drug time release by forming a multi-layered structure of the fibrous material constituting the drug bag and filling the drug between each layer;
d). A method of adjusting the drug time release by forming a number of holes in the material constituting the drug bag for the penetration of saliva and the discharge of the drug dissolved in the saliva, depending on the size of the hole, the number of holes, and the arrangement direction of the holes;
made to allow adjustment of the drug release time in either one or a combination of ways.
An oral drug delivery device using a drug bag.

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