KR20220060598A - Prosthesis for insertion into the body - Google Patents

Abstract

According to the present invention, a prosthesis for insertion into the human body is made of an absorbable polymer material including polycaprolactone (PCL) and has a porous structure so that tissues can be stably adhered to the same. The present invention has an effect of reducing the occurrence of sequelae and the possibility of reoperation, such as the prosthesis being detached from the original position thereof, and shortening the stabilization period.

Description

Prosthesis for insertion into the body

The present invention relates to an implant for insertion into the body that is formed of a polycaprolactone (PCL) material having excellent biodegradability and is formed in a porous structure to stably adhere tissues.

In general, an implant is a material that is inserted into a specific site to preserve its shape or shape. These implants are medically used to treat defects caused by trauma or birth defects, or to be implanted into the body for cosmetic purposes.

That is, the implant is manufactured in various forms according to the purpose, characteristics, and use of the implant, and the part to be inserted into the body may vary depending on the form.

In the case of implants used for cosmetic purposes, as interest in appearance increases, plastic surgery that changes and supplements appearance through surgical operations is popular so that you can lead a better life with confidence in social life. In particular, since the shape of the nose located in the center of the face greatly affects the impression of the face, interest in nose plastic surgery is high.

And in the case of an implant used for treatment, it is inserted into various areas such as joints, knee bones, and fractured areas to firmly fix the area until it is completely cured.

As described above, a method of using an implant made of silicone is common for cosmetic or therapeutic implants, but these silicone implants do not decompose in the human body, and thus remain in the human body even if time elapses.

In addition, in the case of a conventional implant, it is difficult to form an unity with the surrounding tissue due to its material, and it lacks tissue-friendly properties, thereby weakening the surrounding normal tissue during implantation in the body, thereby hindering adhesion between the implant and tissue. Due to this, there is a problem in that sequelae such as deviation from the original position before the implant is completely adhered to the tissue occurs, thereby increasing the possibility of reoperation.

Therefore, the present invention has been derived to solve the above problems, and the present invention provides an implant for insertion into the body that is formed of polycaprolactone material to increase the biodegradability of the implant, and has a porous structure for easy tissue adhesion. Its purpose is to provide

Other objects of the present invention will become clearer through the examples described below.

The implantable prosthesis according to an aspect of the present invention may be formed of an absorbent polymer material including polycaprolactone (PCL), and may have a porous structure.

The prosthesis is inserted into the nasal cavity and may include a stick-shaped pillar support having a certain width, and a convex support formed in the shape of a dome convex upward and having a diameter corresponding to the width of the pillar support at the end of the pillar support. .

The prosthesis may be inserted into at least one of the inside of the face, the knee bone, and the joint, and may be formed in the form of a stick having a circular, oval, or polygonal cross-section.

The prosthesis may be inserted into the chest and formed in a dome shape having a convex shape.

A plurality of protrusions formed of a material that is absorbed into the body at a faster rate than the polycaprolactone may be protruded inside the porous structure.

The prosthesis may be inserted between the bones, and a bone-forming material may be provided inside the porous structure.

The prosthesis may be formed in a spring shape surrounding the outer circumferential surface of a needle formed in the shape of a needle.

The prosthesis for insertion into the body according to the present invention provides the following effects.

The present invention has the effect of having excellent biodegradability by forming the implant with polycaprolactone material.

In addition, the present invention forms the structure of the implant in a porous structure so that the tissue is naturally adhered, so that the implant can be firmly and stably fixed. It has the effect of shortening the period.

Effects of the present invention are not limited to those mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the following description.

1 (A), (B), (C) is a view illustrating an implant for insertion into the body according to a first embodiment of the present invention.
Figure 2 is a perspective view illustrating a deformed shape of the pillar support illustrated in Figure 1;
3 is a perspective view illustrating an implant for insertion into the body according to the second embodiment.
4 to 8 are perspective views illustrating a deformed shape of the implant for insertion into the body illustrated in FIG. 3 .
9 is a perspective view illustrating an implant for insertion into the body according to the third embodiment;
10 is a perspective view illustrating a modified internal structure of the implant for insertion into the body illustrated in FIG. 9 .
11 to 13 are perspective views illustrating modified examples of the implant shown in FIG. 9 .
14 is a perspective view illustrating an implant for insertion into the body according to the fourth embodiment;

Since the present invention can apply various transformations and can have various embodiments, specific embodiments are illustrated in the drawings and described in detail in the detailed description. However, this is not intended to limit the present invention to specific embodiments, and should be understood to include all modifications, equivalents, and substitutes included in the spirit and scope of the present invention. In describing the present invention, if it is determined that a detailed description of a related known technology may obscure the gist of the present invention, the detailed description thereof will be omitted.

The terms used in the present application are only used to describe specific embodiments, and are not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly dictates otherwise. In the present application, terms such as “comprise” or “have” are intended to designate that a feature, number, step, operation, component, part, or combination thereof described in the specification exists, but one or more other features It is to be understood that this does not preclude the possibility of addition or existence of numbers, steps, operations, components, parts, or combinations thereof.

Terms such as first, second, etc. may be used to describe various elements, but the elements should not be limited by the terms. The above terms are used only for the purpose of distinguishing one component from another.

Hereinafter, embodiments according to the present invention will be described in detail with reference to the accompanying drawings, and in the description with reference to the accompanying drawings, the same or corresponding components, regardless of reference numerals, are given the same reference numbers and overlapped therewith. A description will be omitted.

Hereinafter, the implants 10, 20, and 30 for insertion into the body according to an embodiment of the present invention will be described in detail with reference to the drawings.

The implantable implants 10, 20, and 30 according to an embodiment of the present invention are inserted into the body to correct the insertion site, and are formed of an absorbent polymer material containing polycaprolactone (POLY CAPROLACTONE, PCL) and are biodegradable. This excellent, tissue-friendly property has the advantage of not weakening the surrounding normal tissue during implantation in the body, and has the advantage that the tissue can be easily adhered and stably fixed by being formed into a porous structure.

In addition, the implants 10, 20, 30 for insertion into the body of the present invention can be manufactured by 3D printing, thereby providing convenience in manufacturing.

The implants 10, 20, and 30 for insertion into the body are manufactured in various shapes depending on the purpose, characteristics, and use of the surgery, and the insertion site may vary depending on the shape, and may be inserted into the body of an animal as well as the human body. It is also possible

1 (A), (B), (C) is a perspective view, a plan view, and a side view illustrating a prosthesis for insertion into the body according to the first embodiment of the present invention.

Referring to FIG. 1 , the implant 10 for insertion into the body according to the present embodiment may be inserted into the nasal cavity to correct or correct the nose.

The prosthesis 10 includes a pillar support 11 and a convex support 12 .

The pillar support 11 is formed of an absorbable polymer material including polycaprolactone (POLY CAPROLACTONE, PCL), and may be formed in a plate shape having a predetermined width and height. The pillar support 11 may be disposed in the nasal cavity in the longitudinal direction of the nose so that the end thereof faces the tip of the nose.

Polycaprolactone (POLY CAPROLACTONE, PCL) is a biodegradable material with excellent biocompatibility. In addition, polycaprolactone has tissue-friendly properties and is maintained for a long time in the body without weakening surrounding normal tissues when transplanted into the body. In addition, polycaprolactone promotes collagen production, providing a soft feeling without a foreign body feeling.

The convex support part 12 is formed of an absorbable polymer material including polycaprolactone (POLY CAPROLACTONE, PCL), and may be formed in a dome shape convex upward from the end of the column support part 11 . The diameter of the convex support part 12 may be formed to have a smaller diameter than the width of the pillar support part 11 . At this time, the upper end of the pillar support part 11 in contact with the convex support part 12 may be formed to be inclined upwardly toward the lower part of the convex support part 12 . The convex support part 12 is positioned between the nasal tip cartilages to support the nose tip in a raised state.

The inside of at least one of the pillar support 11 and the convex support 12 is formed in a porous structure in which a plurality of vent holes 13 are formed.

The ventilation hole 13 increases the area of adhesion between the implant 10 and the tissue inserted into the human body, thereby helping the tissue to adhere stably, thereby preventing the implant 10 from being separated from the inserted position. In addition, all or part of the vent 13 may be formed to have an irregular diameter and arrangement, so that the tissue may be more firmly adhered.

The prosthesis 10 of this embodiment may change the strength of the prosthesis 10 itself by adjusting the size of the diameter of the ventilation hole 13 .

In this embodiment, the porous structure of the implant 10 may be formed of a mesh 14 structure (see FIG. 2 ). Alternatively, the implant 10 may be formed in a honeycomb structure (not shown).

A plurality of projections (not shown) formed of a material of polylactic acid (PLA) that is absorbed into the body at a faster rate than polycaprolactone protrude inside the porous structure (13 in FIG. 1 and 14 in FIG. 2 ) can be

The plurality of protrusions further increases the adhesion area of the tissue to be adhered to the porous structure (13 in FIG. And, since the plurality of protrusions are formed of polylactic acid, after the tissue is adhered to the porous structure (Fig. 1 (13, Fig. 2 (14))), it is absorbed and decomposed more rapidly than the implant, thereby decomposing the entire implant 10. It is possible to reduce the weight of the body, which has the advantage of increasing the wearing comfort.

The pillar support 11 described above is illustrated as extending from the center of the flat lower surface of the convex support 12, but may be connected eccentrically from the center of the convex support 12 depending on the shape or size of the nose.

3 is a perspective view illustrating the prosthesis 20 for insertion into the body according to the second embodiment.

The implant 20 according to the second embodiment may be inserted into at least one of the inside of the face, bones, and joints.

The implant 20 is formed of an absorbable polymer material including polycaprolactone (POLY CAPROLACTONE, PCL), and may be formed in a stick shape having a predetermined length. The prosthesis 10 may be formed to have a circular cross-section as shown, or to have an elliptical or polygonal cross-section.

The prosthesis 10 may be formed in the form of a straight line or bent with a certain curvature depending on the insertion site of the human body. And the prosthesis 10 may be formed to have a cut surface.

The interior of the implant 20 may be formed in a porous structure in which a plurality of vent holes 22 communicating with the outside are formed.

The ventilation hole 22 increases the area of adhesion between the implant 20 and the tissue inserted into the human body, thereby helping the tissue to adhere stably, thereby preventing the implant 10 from being separated from the inserted position.

The strength of the implant 20 of the present embodiment may be changed according to the size of the diameter of the vents 22 or the number of vents 22 . In addition, the vent holes 22 may have irregular diameters 23 and 24 and arrangement in order to firmly adhere the tissue. Although the irregular diameters 23 and 24 and the arrangement are shown to be formed only at the end of the prosthesis 20, this is only for convenience of explanation. can be formed.

In this embodiment, the porous structure of the implant 20 may be formed in a honeycomb structure or a mesh structure.

A plurality of protrusions (not shown) formed of a material of polylactic acid (PLA) that is absorbed into the body at a faster rate than polycaprolactone may protrude inside the vent 22 .

The plurality of protrusions further increase the adhesion area of the tissue to be adhered to the vent 22, and thus, the tissue may be entangled and adhered to the plurality of protrusions, thereby increasing the bonding force. And, since the plurality of protrusions are formed of polylactic acid, after the tissue is adhered to the vent 13, it is absorbed and decomposed into the body faster than the implant, thereby reducing the weight of the entire implant 10, thereby improving the wearing comfort. There are advantages to increasing it.

On the other hand, the prosthesis 20 according to the second embodiment may be manufactured by being changed into various shapes. For example, as shown in FIG. 4 , the implant 20 may have a porous structure with an inner mesh structure 25 .

And, as shown in FIG. 5 , the prosthesis 20 may be formed in the form of a hemisphere in which a plurality of vent holes 22 are formed and at least one end thereof is convex.

In addition, as shown in FIG. 6 , the implant 20 may have a porous structure inside the mesh structure 25 , and may be formed in a hemispherical shape with at least one end of which is convex.

In addition, the prosthesis 20 may be formed in the form of a capsule in which the ventilation holes 22 are formed as shown in FIG. 7 and both ends are formed in the form of hemispheres. In this case, the cross-section of the capsule may be formed in any one of a circular shape, an oval shape, or a polygonal shape.

And, as shown in FIG. 8 , the capsule-shaped implant 20 may be formed in a porous structure with an inner mesh structure 26 .

On the other hand, when the implant 20 is inserted into a bone (eg, a fracture site), a bone-forming material (not shown) may be provided inside the porous structure (ventilation hole or mesh structure). Osteogenic substances can enhance the rate of fusion between bones.

The bone-forming material may include bone morphogenetic protein 2 (BMP-2), which is a bone-forming protein. In addition, bone-forming materials include biodegradable polymers (PLLA, PLGA, PCL, etc.), natural polymers (chitosan, chitin, cellulose, collagen, hyaluronic acid, etc.) It may further include at least one of the bone formation auxiliary material. Such bone-forming material may be applied to the interior of the porous structure in a liquid state and then cured or may be attached to the interior of the porous structure in a solid state. It is possible for the bone tissue to rapidly adhere to the implant 20 by the bone-forming material.

For example, before being inserted between the bones, the bone-forming material is filled in the entire interior of the porous structure to increase the strength of the implant 20, and after being inserted between the bones, the bone-forming material is absorbed into the body and turns the inside of the implant 10 into a porous structure. can be transformed.

9 is a perspective view illustrating the implant 30 for insertion into the body according to the third embodiment.

The implant 30 according to the third embodiment may be inserted into the chest.

The implant 30 is made of an absorbable polymer material including polycaprolactone (POLY CAPROLACTONE, PCL), and may be formed in a dome shape having a convex shape. The overall size of the implant 30 or the curvature of the convex portion may be manufactured differently depending on the shape and size of the breast.

The prosthesis 30 is formed in a porous structure in which the entire mesh structure 32 or a honeycomb structure is formed.

As such, the implant 30 having a porous structure increases the adhesion area of the tissue to help the tissue to adhere stably, thereby preventing the implant 10 from being separated from the inserted position.

The strength of the implant 30 according to the spacing, size, and arrangement of the mesh structure 32 or the honeycomb structure of the implant 30 of the present embodiment may be changed. In addition, the mesh structure 32 or the honeycomb structure of the prosthesis 30 may have an irregular spacing, size, and arrangement in whole or in part of the region.

In the present embodiment, the prosthesis 30 may be formed by being deformed into various shapes.

For example, the implant 30 may be formed in a porous structure in which a plurality of ventilation holes 31 are formed instead of a mesh structure (see FIG. 10 ). In addition, the implant 30 may be formed in the form of a water droplet having an inner mesh structure 33 and an asymmetrical cross-section of a convex portion (see FIG. 11 ).

And the implant 30 may be formed in a spherical shape of a porous structure in which a plurality of vents 34 are formed (see FIG. 12 ). In addition, the prosthesis 30 may be formed in the shape of a sphere having a porous structure formed with a mesh structure 35 inside (see FIG. 13 ).

A plurality of protrusions (not shown) formed of a material of polylactic acid (PLA) that is absorbed into the body at a faster rate than polycaprolactone protrude inside the porous structure (ventilation hole or mesh structure) of the implant 30 . can be formed.

The plurality of protrusions further increase the adhesion area of the tissues adhering to the prosthesis 30 , and thus the tissues may be entangled and adhered to the plurality of protrusions, thereby increasing bonding force. And, since the plurality of protrusions are formed of polylactic acid, after the tissue is adhered to the porous structure, it is absorbed and decomposed more quickly than the implant, thereby reducing the weight of the entire implant 30, thereby increasing the wearing comfort. There are advantages.

14 is a perspective view illustrating an implant 40 for insertion into the body according to the fourth embodiment.

Referring to FIG. 14 , the implant 40 according to the fourth embodiment may be formed in a spring shape made of polycaprolactone (PCL) material.

The prosthesis 40 formed in the spring shape may be positioned to surround the outer peripheral surface of the needle 51 formed in the needle shape before being injected into the human body. In addition, the prosthesis 40 may be positioned inside the human body in such a way that only the needle 51 comes out of the body after being injected into the body together with the needle.

When the external pressure is applied using the spring-shaped elasticity of the prosthesis 40 formed in this way, the outer shape is deformed, and when the external pressure is released, it is restored to the original shape, and the space in which the prosthesis 40 is injected is stably maintained. can do it

Although the above has been described with reference to one embodiment of the present invention, those of ordinary skill in the art may change the present invention in various ways within the scope not departing from the spirit and scope of the present invention described in the claims below. It will be appreciated that modifications and variations are possible.

10: implant
11: Column support
12: convex support
13: vent

Claims (7)

In the implantable implant to be inserted into the human body,
An implant for insertion into the body that is made of an absorbent polymer material including polycaprolactone (PCL) and has a porous structure. According to claim 1,
The prosthesis is inserted into the nasal cavity,
A prosthesis for insertion into the body, comprising: a stick-shaped pillar support having a predetermined width; and a convex support formed in the shape of a dome convex upward and having a diameter corresponding to the width of the pillar support at an end of the pillar support. According to claim 1,
The implant is inserted into at least one of the inside of the face, the knee bone, and the joint, and is formed in the form of a stick having a circular, oval, or polygonal cross-section. According to claim 1,
The implant is inserted into the chest, and is formed in a dome shape having a convex shape. According to claim 1,
The prosthesis for insertion into the body, characterized in that a plurality of protrusions formed of a material that is absorbed into the body at a faster rate than the polycaprolactone protrude inside the porous structure. According to claim 1,
The implant is inserted into the bone,
An implant for insertion into the body provided with a bone-forming material inside the porous structure. According to claim 1,
The implant is
An implant for insertion into the body, characterized in that it is formed in the shape of a spring that surrounds the outer peripheral surface of the needle formed in the shape of a needle.

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