KR20220053150A - Devices for delivering drugs to the oral cavity - Google Patents

Abstract

The present invention relates to an intra-oral drug delivery device configured to deliver drugs slowly over a predetermined duration time, in which a semi-circular band type mouthpiece is composed of an external periphery mouthpiece inserted into the outer periphery of teeth or an internal periphery mouthpiece inserted into the inner periphery of teeth, a position changing coupling structure that couples a drug storage unit by changing a position at which the drug storage unit is coupled is formed on the mouthpiece, and the drug storage unit is composed of a drug pocket having one or more drug injection holes and a drug inlet port. When drugs are injected into the drug storage unit, and the drug storage unit is inserted into the mouth, saliva flows into the drug storage unit and the drugs dissolved in the saliva are delivered into the oral cavity through the drug injection holes. A drug delivery time can be set differently according to the size and number of drug injection holes and positions at which the drug injection holes are formed.

Description

Device for delivering drugs to the oral cavity

The present invention relates to an oral drug delivery device. More particularly, the present invention relates to an intraoral drug delivery device for slow-released delivery of a drug in the oral cavity.

In general, drugs supplied to obtain effects by acting on tissues in the oral cavity are manufactured in the form of ointments or liquids, and are applied directly to the user's teeth or gums, or sprayed into the oral cavity using a supply device such as a spray. Or it has been used as a method of spitting out after brushing for a certain period of time.

However, since the inside of a person's oral cavity is always wet with saliva, even if an ointment or liquid drug is applied, it is diluted or washed away by saliva within a short period of time.

Therefore, there is a disadvantage in that there is a lot of inconvenience because it is necessary to periodically apply or spray the drug in order to treat the drug for a long time. In addition, since it is practically impossible to supply the drug at the correct time during daily life, there is a problem in that it is difficult to expect high drug efficacy. In addition, since oral drugs are swallowed together with water, preparation or application of drugs that need to be absorbed and dissolved in the oral cavity is limited.

In order to solve this problem, a method has been proposed in which a drug is made in the form of candy or gum so that the patient can hold it in the mouth for a long time. It is easily swallowed and has the disadvantage of low reliability.

In consideration of the above problems, as a prior art, a continuous drug delivery device through the mouth has been proposed in Korean Patent Application Laid-Open No. 10-2016-0084422. It comprises a fastener for removably securing the drug delivery device to the surface of the patient's mouth, an electrical or mechanical pump, and a pharmaceutical composition comprising levodopa or a levodopa prodrug, having a volume of 01 mL to 5 mL, as a suspension or A drug for continuous or semi-continuous intraoral administration of a pharmaceutical composition comprising the drug and configured to be removably inserted into the mouth of a patient comprising an oral liquid impermeable drug reservoir comprising as a solid and an automatic stop/start portion A delivery device has been proposed.

The prior art as described above includes a retainer that attaches the fastener to the teeth, and a drug storage unit having an electrical and mechanical pump on the fastener is installed to be detachably attached to one side of the fastener. The drug injected into the drug reservoir is continuously supplied by a pump, and the drug is transported from the side of the tooth to the lingual side through a tube.

However, there is a problem in that the foreign body feeling is too large in terms of volume or structure because it is necessary to couple the drug storage unit having an electrical or mechanical pump to the fastener coupled in the mouth.

Korean Patent Application Laid-Open No. 10-2016-0084422 (Title of the invention: continuous drug delivery device through the mouth) (published on July 13, 2016)

It is an object of the present invention to provide an oral drug delivery device capable of slowly delivering a drug into the oral cavity.

Another object of the present invention is to provide an intraoral drug delivery device composed of a design and material that makes it easy to separate the oral drug delivery device and minimizes discomfort even when worn for a long time by reducing a possible foreign body feeling.

An oral drug delivery device for achieving the object of the present invention,

A mouthpiece made to be inserted into and removed from the oral cavity in a semi-circular rim shape in contact with the teeth and gums; and a drug storage unit that is formed or detached from the mouthpiece, wherein the drug storage unit stores a drug soluble in saliva, and is configured to deliver the drug dissolved in saliva into the oral cavity.

The present invention is a device for intraoral drug delivery device that combines a band-type mouthpiece with a drug storage unit and inserts it into the mouth so that the drug is slowly dissolved in saliva and delivered into the oral cavity.

The mouthpiece is composed of only a band portion made of a soft cushion member, and can be inserted into the mouth by inserting it into the outer periphery or inner periphery of the tooth arrangement. That is, the mouthpiece of the present invention may be composed of either an outer periphery mouthpiece inserted into the outer periphery of the tooth arrangement or an inner periphery mouthpiece inserted into the inner periphery of the tooth arrangement.

In addition, the band portion in contact with the teeth and gums may be configured such that the elastic member is embedded in the outer shell made of the cushion member, or the elastic member is externally coupled to the band portion made of the cushion member.

In addition, as a structure for preventing separation of the mouthpiece and fixing it to the tooth arrangement, a hook portion caught on the front teeth may be formed.

In addition, by forming a cover portion on the molars at both ends of the mouthpiece to cover the upper surface of the molars, it is possible to prevent separation and prevent bruising.

In addition, it is possible to prevent separation by forming a girder portion instead of a cover portion to cover 2-3 molars. The mouthpiece may have a drug storage unit integrally formed or may have a detachable structure.

The drug storage unit is formed with a pocket for inserting the drug therein through the input unit, and one or more drug injection holes that are passages through which saliva is introduced into the pocket or the drug is delivered into the oral cavity together with the saliva.

In addition, the drug storage unit may be configured to form a rail in the mouthpiece, form a rail groove in the drug storage unit, combine, and slide to adjust the position.

Alternatively, a coupling rod may be formed in the mouthpiece, and a coupling groove may be formed in the drug storage unit to be coupled to a desired position.

In addition, the drug storage unit may further include a pocket holder coupled to the mouthpiece, and may be configured to have a structure in which the drug storage unit is detached from the pocket holder so that the drug storage pocket can be used for one-time use.

It is also possible to use the drug packet directly coupled to the pocket holder.

On the other hand, the drug storage of the present invention is formed to correspond to each other on the left and right sides of the mouthpiece, it can be configured to support both sides of the tongue by configuring the protrusion. It can be used for drug delivery and at the same time, it can be used as a tool for preventing snoring and lifespan apnea by supporting the tongue during sleep to prevent the tongue from being pushed into the airway.

The present invention can provide an intraoral drug delivery device in which a drug is dissolved in saliva and gradually delivered into the oral cavity by attaching a drug storage unit to the mouthpiece. Accordingly, when the drug is slowly taken or delivered in the oral cavity for a long time and the drug is put into the drug storage unit and inserted into the mouth, the drug dissolved in saliva is gradually delivered into the oral cavity, so that the drug can be delivered slowly for a long time.

The present invention allows the drug delivery time to be controlled differently even for the same drug by varying the size or number of drug injection holes formed in the drug storage unit.

In addition, the present invention is configured to be able to change the binding position of the liquid storage unit, it is possible to deliver the drug by targeting the desired position.

In addition, the present invention is configured as an outer periphery mouthpiece type to be inserted into the outer periphery of teeth or an inner periphery mouthpiece type to be inserted into the inner periphery of teeth so that it can be selectively used according to the user's oral condition.

In addition, the present invention is provided with a pocket holder coupled to the mouthpiece, and the drug pocket is configured to be detachable from the pocket holder, so that the drug pocket can be used as a disposable to reduce the difficulty of cleaning.

In addition, it is possible to reduce the difficulty of washing when reused by allowing the solidified drug packet to be directly combined with the pocket holder.

In addition, the drug packet is composed of a film layer and a drug layer in a multi-layer structure to control the thickness of the film layer and the drug layer that dissolves in saliva, so that the drug can be prepared and used to control the time that the drug is dissolved in saliva and delivered.

In addition, the present invention has an effect that can be used as a drug delivery device as well as for preventing snoring by forming a pair of drug storage units formed in the mouthpiece in a sinusoidal manner to support the middle drug side of the tongue.

1 (A) and (B) are diagrams illustrating the configuration of an intraoral drug delivery device having an outer periphery mouthpiece according to the present invention.
2 (A) and (B) are diagrams illustrating the configuration of an intraoral drug delivery device having an inner periphery mouthpiece according to the present invention.
3 is a view for explaining the structure of the variable drug storage location of the drug delivery device according to the present invention.
4 is an exemplary configuration diagram showing another embodiment of the mouthpiece according to the present invention.
5 is an exemplary diagram illustrating the configuration of the drug storage unit mounted on the inner periphery mouthpiece with the cover unit of the oral drug delivery device of the present invention.
6 is an explanatory view of the variable-position mounting structure of the drug storage unit of the oral drug delivery device according to the present invention.
7 (A) and (B) are exemplary views of a mouthpiece having a girder part of the oral drug delivery device according to the present invention.
8 (A) and (B) are exemplary views showing another configuration of the drug storage unit of the oral drug delivery device according to the present invention.
9 is an exemplary view of the drug storage unit of the oral drug delivery device according to the present invention.
10 (A) and (B) are schematic diagrams showing another embodiment of the oral drug delivery device according to the present invention.

The following is merely illustrative of the principles of the invention. Therefore, those skilled in the art will be able to devise various devices and methods that, although not explicitly described or shown herein, embody the principles of the present invention and are included within the spirit and scope of the present invention. In addition, all conditional terms and examples listed herein are, in principle, expressly intended only for the purpose of understanding the concept of the present invention, and it should be understood that they are not limited to the specifically enumerated embodiments and states as such. do.

Moreover, it is to be understood that all detailed description reciting the principles, aspects, and embodiments of the invention, as well as specific embodiments, are intended to cover structural and functional equivalents of such matters. It should also be understood that such equivalents include not only currently known equivalents, but also equivalents developed in the future, i.e., all devices invented to perform the same function, regardless of structure.

The above objects, features and advantages will become more apparent through the following detailed description in relation to the accompanying drawings, and accordingly, those of ordinary skill in the art to which the present invention pertains can easily implement the technical idea of the present invention. There will be. In addition, when it is determined that the detailed description of the known technology related to the present invention may unnecessarily obscure the gist of the present invention in carrying out the present invention, the detailed description thereof will be omitted.

The terms used in the present application are only used to describe specific embodiments, and are not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly dictates otherwise. In the present application, terms such as “comprise” or “have” are intended to designate that a feature, number, step, operation, component, part, or combination thereof described in the specification exists, but one or more other features It should be understood that this does not preclude the existence or addition of numbers, steps, operations, components, parts, or combinations thereof.

Hereinafter, preferred embodiments of the present invention will be described in more detail with reference to the accompanying drawings. In describing the present invention, in order to facilitate the overall understanding, the same reference numerals are used for the same components in the drawings, and duplicate descriptions of the same components are omitted.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 (A) and (B) are diagrams illustrating the configuration of an intraoral drug delivery device having an outer periphery mouthpiece according to the present invention.

A mouthpiece (10) made of a semi-circular rim shape in contact with the teeth and gums, which can be inserted into the mouth and easily taken out;

It is formed integrally with the mouthpiece 10 or consists of a drug storage unit 20 that is detachable from the mouthpiece,

The drug storage unit 20 includes a drug pocket into which a drug is inserted, and at least one drug injection hole formed in the drug pocket.

2 (A) and (B) are diagrams illustrating the configuration of an intraoral drug delivery device having an inner periphery mouthpiece according to the present invention.

The mouthpiece 10 is, as shown in FIG. 1, an outer periphery mouthpiece in contact with the outer periphery of the tooth arrangement, or an inner periphery mouthpiece in contact with the inner periphery of the tooth arrangement as shown in FIG. 2 . can be

That is, the mouthpiece 10 of the present invention is an outer periphery mouthpiece fitted between a tooth and a ball in contact with the outer periphery of the tooth arrangement or an inner periphery mouthpiece inserted between the teeth and the tongue in contact with the inner periphery of the tooth arrangement. can be configured.

The mouthpiece 10 is a band part 11 made of a silicone or plastic material molded into a semicircular rim shape in contact with the tooth outer periphery or the inner periphery of the tooth, and the band part for fixing the band part 11 to the tooth by hooking the band part 11 to the tooth. (11) is formed to protrude from the hook portion 13, and is formed on the side of the band portion 11 is configured to include a rail portion 14 for coupling the drug storage unit 20 to a desired position.

The band part 11 may be composed of an elastic member 12 and a cushion member surrounding the elastic part 12 . The elastic member 12 is made to have an elastic restoring force in a direction in close contact with the teeth and gums. The cushion member is configured to form a shell surrounding the elastic member 12 . The cushion member is made of a material having a cushioning function that minimizes irritation to the gums when in contact with the gums.

In addition, the elastic member 12 and the cushion member are not formed as one body, but may be configured as a separate type. The outer periphery mouthpiece 10 may be configured such that the cushion member is in contact with the teeth and gums, and the elastic member 12 is coupled to the outer periphery of the cushion member. In the case of the inner periphery mouthpiece, the cushion member is in contact with the teeth and gums, and the elastic member 12 is made to have elasticity in the form of opening from the inside, so that it can be configured to be closely coupled to the inner periphery of the cushion member.

In addition, the mouthpiece 10 further includes a hook portion 13 to be hung on at least one or more incisors so that the mouthpiece 10 is not easily separated and removed. The hook portion 13 has a hook portion formed on the inside in the outer periphery mouthpiece 10, and a hook portion formed on the outside in the mouthpiece on the inner periphery.

On the other hand, the structure for coupling the drug storage unit 20 to the mouthpiece 10 is configured to be able to change the coupling position. As a structure that can change the coupling position, a guide rail 14 is formed on the mouthpiece 10 as shown in FIGS. 1 and 2 , and the guide rail 14 is coupled to the guide rail 14 in the drug storage unit 20 and slides. It can be configured by including a rail groove that can be installed.

In addition, Figure 3 is a view for explaining the structure of the variable drug storage location of the drug delivery device according to the present invention.

In the present invention, as a variable coupling structure for coupling the drug storage unit 20 to the mouthpiece 10, there may be a structure in which a rail and a rail groove are formed and coupled to correspond to each other as shown in FIGS. 1 and 2 . However, it is difficult to couple the drug storage unit 20 to the rail because the bending angle is large in the front teeth.

In consideration of this problem, the present invention can propose a band-type variable coupling structure as shown in FIG. 3 . As shown in FIG. 3 , the mouthpiece 10 is composed of a soft band without a protruding part, and a band 23 for sliding the mouthpiece 10 body is further formed on the back of the drug storage unit 20 . This is by sliding the mouthpiece 10 body into the band 23, so that the drug storage unit 20 can be coupled to a desired position.

The reason for having a structure for changing the binding position of the drug storage unit 20 as described above is to target the position at which the drug is delivered. That is, by allowing the position of the drug storage unit 20 to be variable, the drug can be injected at a desired position.

The drug storage unit 20 is configured to include a pocket 21 for inserting and storing the drug 30 through the inlet 21a, and at least one drug injection hole 21b formed in the pocket 21 . .

In addition, the drug storage unit 20, the bracket 22 having a band 23 on the back side, and the front side of the bracket 22 are formed with protrusions formed on the rim and the central portion, and the drug pocket is inserted into the protrusion and coupled It can also be configured as a structure that This may be configured as a package depending on the drug to be put into the drug pocket itself, and then used by combining it with the bracket, and then discarding the pocket. Since only the pocket 21 needs to be separated and thrown away after being used once, problems such as residual drug or contamination can be solved. The bracket 22 to which the band 23 is attached can be washed and reused together with the mouthpiece 10 .

At least one drug injection hole 21a is formed in the drug storage unit 20 . By combining the number, size, and formation position of the drug injection holes 21b, it is possible to adjust the time and amount of drug injected by slowly dissolving the drug in saliva.

4 is an exemplary configuration diagram showing another embodiment of the mouthpiece according to the present invention.

The mouthpiece 10 includes a band portion 11, a hook portion 13 formed on the band portion 11, and a rail portion 14 for coupling the drug storage portion 20, the amount of the band portion 11 The end is configured to further include a cover portion 15 formed to cover the upper surface of the tooth from the upper side.

Here, the band portion 11 may be made of a flexible silicone material that maintains its shape by itself, may be configured in a form in which an elastic member is embedded in a cushion member, and the cushion member and the elastic member may have a dual structure. Also, the elastic member may be configured in a separated form. The elastic member may be formed of a plastic band, or may be formed by forming an elastic wire in a clip type. This is to prevent the mat piece from coming off by itself when it is inserted and worn in response to the teeth, so there is no need to tighten it strongly.

The cover part 15 is a cover structure that covers the upper surface of the molars, and when the mouth is closed, the upper and lower molars are bitten, and when the mouth is slightly opened, the cover part is caught on the upper teeth. In addition, the cover part is located between the upper and lower molars, so it can also serve to prevent bruising.

As shown in Figure 4, the rail portion 14 is configured in the shape of a protruding head from the band portion 14, and the protruding head is inserted from the side to the bracket 22 of the drug storage unit 20 to prevent it from falling out (24) this is formed It is possible to slide the rail portion 14 in the shape of a protruding head by inserting it into the rail groove 24 . Therefore, the installation position of the drug storage unit 20 can be adjusted to a desired position. However, since the incisors have a curvature that is difficult to slide by coupling the rails to the rail grooves, a different method must be used to mount the drug storage unit 20 to the incisors.

5 is an exemplary configuration diagram in which the drug storage unit is mounted on the inner periphery mouthpiece having the cover part of the oral drug delivery device of the present invention. As a structure corresponding to the outer periphery mouthpiece of FIG. 4, the band portion 11 is inserted into the inner periphery of the tooth arrangement, and the cover portion 15 is configured as an outwardly bent shape, and the rail portion 14 is formed on the inner periphery of the band portion 11, the drug storage unit 20 is attached to the inner periphery of the mouthpiece (10) is installed.

6 is an explanatory view of the variable position mounting structure of the drug storage unit of the oral drug delivery device according to the present invention. As shown in FIG. 6 , a head-mounted coupling rod 16 protruding at regular intervals is formed on the band portion 11 of the mouthpiece 10 , and in response thereto, the coupling rod 16 is provided in the drug storage unit 20 . ) is configured by forming a coupling groove 25 that can be forcibly inserted and removed. By configuring the head of the coupling rod 16 or the coupling groove 25 of a flexible material, it can be configured to enable forced fitting and forced separation. Therefore, since one coupling rod and the coupling groove are coupled, it is possible to select a location to be coupled or separated regardless of the curvature of the band portion.

7 (A) and (B) are exemplary views of a mouthpiece having a girder part of the oral drug delivery device according to the present invention.

Figure 7 (a) shows the configuration of the mouthpiece on the outer periphery, Figure 7 (b) shows the configuration of the mouthpiece on the inner periphery. When the mouthpiece 10 made of only the band part is inserted into the outer periphery of the tooth or the inner periphery of the tooth, there may be a risk of basil easily. In consideration of this, a girder portion 17 surrounding the inner and outer sides and the upper surface of 1-2 or 2-3 molars is formed. The mouthpiece 10 forming the girder unit 170 is coupled with the girder unit 17 covered with a cap type on the molars. Since the girder part 17 is covered with the molars, there is no fear of being easily separated from the mouth and falling out. In order to take it out, you have to hold your mouth farther away and lift it up with your hand to prevent it from falling out on its own, and restrict its flow. According to the type of the mouthpiece 10, the girder portion 17 is formed in the outer periphery of the mouthpiece in the inward direction and the inner periphery of the mouthpiece in the outward direction.

The drug storage unit 20 may be formed integrally with the mouthpiece 10 or may be configured to be detachable. The one-piece structure is formed as a pocket type, so that the drug is put into the pocket, and saliva is introduced through at least one drug injection hole formed in the pocket, or the drug dissolved in the saliva is delivered into the oral cavity together with the saliva. By varying the size, number, or formation position of the drug injection hole, the drug delivery time can be varied. Drug delivery time can be slowed by slowly dissolving the drug in saliva and slowly injecting it into the oral cavity.

When the drug storage unit 20 is formed in a pocket type, there is a disadvantage in that the position is fixed and it is difficult to deliver the drug by targeting the desired position. In consideration of these disadvantages, in the present invention, the rail portion 14 is formed on the band portion 11 so that the drug storage portion 20 is coupled and then slid so that it can be combined at a desired position. This makes it possible to deliver the drug to the desired location.

In addition, the pocket type must be washed after use, but it may be difficult to clean. It is difficult to clean and there is a risk of contamination by residual drugs or saliva in the pocket. Accordingly, the pocket 21 can be configured to be disposable.

8 (A) and (B) are diagrams illustrating the configuration of the drug storage unit of the oral drug delivery device according to the present invention.

8(A) is configured to include a pocket holder 40 coupled to the mouthpiece 10 and a drug storage unit 20 configured to be coupled/removable to the pocket holder 40 .

The pocket holder 40 is a bracket 41 to which a band 42 for coupling to the mouthpiece 10 is attached, and a plurality of coupling rods protruding from the bracket 41 to couple the drug storage unit 20 . (41a) is provided. The drug storage unit 20 includes a drug pocket 21 having a drug inlet 21a and a plurality of drug injection holes 21b formed therein and storing the drug 30 therein, and a drug pocket 21 . It includes a support portion 22 for supporting, the support portion 22 is formed with a plurality of coupling grooves (22a).

The coupling groove 22a of the drug storage unit 20 is coupled to the coupling rod 41a of the pocket holder 40 to couple the drug storage unit 20 to the drug pocket 40 . The drug pocket 40 may be coupled to the mouthpiece 10 and fixed at a desired position. Here, although the example in which the band 42 is formed on the back surface of the pocket holder 40 is illustrated, the present invention is not limited thereto, and a rail is formed in the mouthpiece, and a rail groove is formed in the pocket holder 40 to couple the structure. It is possible. In addition, the mouthpiece may be configured to form a coupling rod, and to form a coupling groove in the pocket holder for coupling.

Therefore, by having the pocket holder 40 and having a structure in which the drug storage unit 20 is coupled to the pocket holder, the drug storage unit 20 can be used for one-time use. That is, the drug storage unit 20 is not washed and reused, but is disposable and can be replaced.

In addition, (b) of FIG. 8 may be configured as a drug packet 30 instead of a drug storage unit, and a structure for coupling the drug packet 30 to the pocket holder 40 . That is, to form a rim 43a on the pocket holder 40, to form a plurality of protrusions 43b on the inside of the rim 43a, and to apply or solidify a drug in the inner space of the rim 43a. may be Alternatively, the drug may be separately configured as a drug packet 30 and coupled to the plurality of protrusions 43b to be coupled and fixed to the pocket holder 40 . The drug packet 30 may be composed of a solidified packet to be provided with a groove 33 for coupling the drug to the protrusion 43b.

In addition, the drug packet 30 so as to control the drug injection time, the saliva-soluble film layer 31 and the drug layer 32 when solidifying the drug can be configured in a multi-layer structure. This starts to melt from the portion where the film layer 31 is in contact with the saliva. Accordingly, the drug layer 32 may also be gradually brought into contact with the saliva according to the time when the film layer is melted and the drug can be delivered. By forming a plurality of openings 31a in each film layer while the film layer and the drug layer are formed as a multilayer, the drug delivery time can be controlled. Such drug manufacture can be manufactured in a drug packet in which the drug delivery time is set by adjusting the number of film layers, the size of the number of openings, the film layer thickness, the drug layer thickness, etc., manufactured in the pharmaceutical process.

9 is a diagram illustrating another configuration of the drug storage unit of the oral drug delivery device according to the present invention. As shown in FIG. 9 , a configuration for controlling the delivery time for a drug that is not prepared as a separate drug packet is exemplified. The drug storage unit 20 is formed with a plurality of drug pockets 26, and drug injection holes 26a of different sizes are formed for each drug pocket 26.

9 illustrates that two drug pockets are formed, and only one drug injection hole is formed, but at least one drug injection hole may be formed in plurality, and the size of the injection hole may be different. By varying the size or number of injection holes for each drug pocket, and injecting the drug into an appropriate pocket in consideration of the drug delivery time, the desired drug delivery time may be adjusted. In addition, in the case of a detachable drug storage unit, the size of the drug injection hole or the number of injection holes may be different to be configured to be distinguished by a configuration in which the rust delivery time is different. In this way, the drug delivery time can be optimally selected by selectively using the drug storage unit having a structure set to different drug delivery times.

On the other hand, many people suffer from discomfort and pain due to snoring during sleep. Severe snoring can cause sleep apnea, and sleep apnea can cause serious problems. There may be various causes of snoring, but one of the main causes is that the tongue sinks to the root of the tongue during sleep, and the root of the tongue blocks the airway, causing snoring and sleep apnea.

In the present invention, an oral drug delivery device is inserted in the mouth in the form of a mouthpiece to realize the purpose of oral drug delivery. Since such oral drug delivery needs to be continued for a certain period of time or more, it can be used even during sleep. Since the drug delivery device is inserted into the mouth during sleep, in the present invention, the drug delivery device is used to support the tongue during sleep to prevent the tongue from sinking, so that it can be used for the purpose of preventing snoring.

10 (A) and (B) are schematic diagrams showing another embodiment of the oral drug delivery device according to the present invention. As shown in FIG. 10, a pair of drug storage units 200 attached to the mouthpiece 10 to correspond to each other are provided, but the drug storage units 200 are more than teeth to support the left and right sides of the tongue. It can be configured to be formed as a pair of left and right in a higher protrusion type. In the drug storage unit 200 configured in this way, an inlet for injecting a drug and one or more drug injection holes through which a drug dissolved in saliva is delivered into the oral cavity are formed. In addition, the protruding drug storage unit 200 is formed in such a structure that only the lower end is integrally formed with the band portion of the mouthpiece, and the upper end can flow from side to side. Also, the protruding drug storage unit 200 is made of a soft flexible material (eg, silicone) so that the space formed therein becomes a drug pocket.

When configured with the protruding drug storage unit 200 in this way, the left and right sides are supported in the middle part of the tongue as shown in FIG. By supporting the left and right sides of the middle part of the tongue, it is possible to prevent the tongue from sinking to the airway side during sleep in a supine position. This is because the left and right sides of the middle part of the tongue are lifted up by the protruding drug storage unit 200, so the tongue is not pushed down. Therefore, by forming the drug storage unit of the oral drug delivery device of the present invention with the protruding type drug storage unit 200 and forming it on the left and right sides, it is possible to prevent snoring by supporting the jaw side of the tongue in a pushed-up state.

In addition, the upper surface of the protruding drug storage unit 200, the front (front teeth direction) side is high, the rear (airway side) is composed of a lower inclined type. This is to reduce the burden on the tongue. In addition, by connecting the protruding drug storage unit 200 of the present invention to the lower end of the mouthpiece band from the bottom surface, the upper end enables free left and right movement, thereby reducing the burden when supporting the tongue.

As described above, according to the present invention, when a drug is injected by attaching a drug storage unit to the mouthpiece, the drug dissolved by saliva can be gradually delivered into the oral cavity through the drug injection hole. Accordingly, if the drug can be delivered into the oral cavity slowly for a long time, there is an effect that it can be used even during sleep.

In the above, preferred embodiments of the present invention have been illustrated and described, but the present invention is not limited to the specific embodiments described above, and it is common in the technical field to which the present invention pertains without departing from the gist of the present invention as claimed in the claims. Various modifications may be made by those having the knowledge of, of course, and these modifications should not be individually understood from the technical spirit or perspective of the present invention.

10: mouthpiece 11: band part
12: elastic member 13: hook part
14: rail 15: cover part
16: coupling rod 17: girder part
20: drug storage 21: drug pocket
21a: drug inlet 21b: drug injection hole
23: band 24: rail groove
25: coupling groove 30: drug
40: pocket holder

Claims (11)

a mouthpiece having a semi-circular rim shape in contact with teeth and gums, which can be inserted into the mouth and taken out easily;
A drug storage unit formed integrally with the mouthpiece or detachably attached to the mouthpiece,
The drug storage unit, a pocket for inserting a drug therein through the input unit, and one or more drug injection holes that are passages through which saliva is introduced into the pocket or the drug is delivered into the oral cavity together with the saliva are formed
Oral drug delivery device. The method of claim 1,
The mouthpiece is
It is an outer periphery mouthpiece or inner periphery mouthpiece that is composed of only a band portion made of a soft cushion member and is inserted into the mouth in close contact with the outer periphery or inner periphery of the tooth arrangement.
Oral drug delivery device. The method of claim 1,
The mouthpiece is
The band portion in contact with the teeth and gums is configured to embed the elastic member in the outer shell made of a cushion member or to externally couple the elastic member to the band portion made of the cushion member.
Oral drug delivery device. The method of claim 1,
The mouthpiece is
It is a structure for preventing the mouthpiece from being separated and fixing it to the tooth arrangement.
Oral drug delivery device. The method of claim 1,
The mouthpiece is
At both ends of the mouthpiece, a cover part covering the upper surface of some molars or a girder part covering 2-3 molars are formed.
Oral drug delivery device. The method of claim 1,
The drug storage unit, so that the drug delivery duration can be selected by selecting the pockets formed with different sizes of drug injection holes and the number and formation positions of the drug injection holes formed in the pockets of the drug storage unit
Oral drug delivery device. The method of claim 1,
The combined structure of the mouthpiece and the drug storage unit is,
Forming a rail on the opposite surface of the tooth contact surface of the mouthpiece or forming a plurality of coupling rods at regular intervals,
In the drug storage unit, a rail groove fitted to the rail or a coupling groove fitted to the coupling rod is formed to vary the position for coupling the drug storage unit to be coupled.
Oral drug delivery device. The method of claim 1,
The combined structure of the mouthpiece and the drug storage unit is,
Forming a band attached only at both ends to the drug storage unit, inserting the band portion of the mouthpiece between the band and the drug storage unit to change the coupling position of the drug storage unit to combine
Oral drug delivery device. The method of claim 1,
A pocket holder coupled to the mouthpiece is further provided, and the drug storage unit is detachable from the pocket holder so that the drug storage pocket can be used for one-time use.
Oral drug delivery device. 10. The method of claim 9,
The drug packet solidified in the pocket holder is directly coupled, but the drug packet has a saliva-soluble film layer and a drug layer formed in a multi-layered structure, and the film layer and the drug layer are each thick and soluble in saliva by the number of layers. made to control time
Oral drug delivery device. The method of claim 1,
The drug storage unit is formed as a pair to correspond to each other on the left and right sides of the mouthpiece, but is configured in a protruding shape that protrudes higher than the teeth to support both sides of the tongue to prevent the tongue from being pushed into the airway during sleep to prevent snoring preventable
Oral drug delivery device.

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