KR20220011639A - 샘플 내 폴리뉴클레오타이드 서열의 분포분율의 멀티포어 결정 - Google Patents

샘플 내 폴리뉴클레오타이드 서열의 분포분율의 멀티포어 결정 Download PDF

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KR20220011639A
KR20220011639A KR1020217038017A KR20217038017A KR20220011639A KR 20220011639 A KR20220011639 A KR 20220011639A KR 1020217038017 A KR1020217038017 A KR 1020217038017A KR 20217038017 A KR20217038017 A KR 20217038017A KR 20220011639 A KR20220011639 A KR 20220011639A
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South Korea
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target
sample
nanopore
analyte
nanopores
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KR1020217038017A
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English (en)
Korean (ko)
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옌안 자오
윌리엄 맥켄나
윌리엄 비. 던바
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온테라 인크.
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Publication of KR20220011639A publication Critical patent/KR20220011639A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/49—Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020217038017A 2019-04-22 2019-04-22 샘플 내 폴리뉴클레오타이드 서열의 분포분율의 멀티포어 결정 KR20220011639A (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2019/028518 WO2020219011A1 (en) 2019-04-22 2019-04-22 Multipore determination of fractional abundance of polynucleotide sequences in a sample

Publications (1)

Publication Number Publication Date
KR20220011639A true KR20220011639A (ko) 2022-01-28

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Application Number Title Priority Date Filing Date
KR1020217038017A KR20220011639A (ko) 2019-04-22 2019-04-22 샘플 내 폴리뉴클레오타이드 서열의 분포분율의 멀티포어 결정

Country Status (5)

Country Link
EP (1) EP3959331A1 (ja)
JP (1) JP2022530016A (ja)
KR (1) KR20220011639A (ja)
CN (1) CN113966403A (ja)
WO (1) WO2020219011A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114942402B (zh) * 2022-07-20 2022-11-29 武汉格蓝若智能技术有限公司 一种异常电能表定位方法及系统
CN116127288B (zh) * 2023-04-14 2023-09-15 南京邮电大学 基于独立成分分析的纳米孔传感信号噪声去除方法及装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2684801C (en) * 2007-04-04 2017-10-10 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
JP5873023B2 (ja) * 2009-12-01 2016-03-01 オックスフォード ナノポール テクノロジーズ リミテッド 生化学分析機器
CA2973753A1 (en) * 2015-02-02 2016-08-11 Two Pore Guys, Inc. Nanopore detection of target polynucleotides from sample background
US10102338B2 (en) * 2015-09-24 2018-10-16 Genia Technologies, Inc. Adaptive compression and modification of nanopore measurement data
EP3440456B1 (en) * 2016-10-24 2020-12-23 Ontera Inc. Fractional abundance of polynucleotide sequences in a sample

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Publication number Publication date
JP2022530016A (ja) 2022-06-27
CN113966403A (zh) 2022-01-21
EP3959331A1 (en) 2022-03-02
WO2020219011A1 (en) 2020-10-29

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