KR20210098464A - 감염성, 자가 면역 및 알레르기성 질환을 치료하기 위한 방법 및 조성물 - Google Patents

감염성, 자가 면역 및 알레르기성 질환을 치료하기 위한 방법 및 조성물 Download PDF

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KR20210098464A
KR20210098464A KR1020217017306A KR20217017306A KR20210098464A KR 20210098464 A KR20210098464 A KR 20210098464A KR 1020217017306 A KR1020217017306 A KR 1020217017306A KR 20217017306 A KR20217017306 A KR 20217017306A KR 20210098464 A KR20210098464 A KR 20210098464A
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caccae
prebiotic
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cma
butyrate
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캐서린 알. 나글러
리유에 바오
디오니시오스 안토노포울로스
존 더블유. 콜슨
로렌 안데스 헤서
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더 유니버서티 오브 시카고
클로스트라바이오
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
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    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A61K31/716Glucans
    • A61K31/718Starch or degraded starch, e.g. amylose, amylopectin
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    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/24Immunology or allergic disorders

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KR1020217017306A 2018-11-05 2019-11-05 감염성, 자가 면역 및 알레르기성 질환을 치료하기 위한 방법 및 조성물 Ceased KR20210098464A (ko)

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US201862755945P 2018-11-05 2018-11-05
US62/755,945 2018-11-05
PCT/US2019/059865 WO2020097077A1 (en) 2018-11-05 2019-11-05 Methods and compositions for treating infectious, autoimmune, and allergic disease

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KR20210098464A true KR20210098464A (ko) 2021-08-10

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US (1) US12589122B2 (cg-RX-API-DMAC7.html)
EP (1) EP3876755A4 (cg-RX-API-DMAC7.html)
JP (1) JP7737098B2 (cg-RX-API-DMAC7.html)
KR (1) KR20210098464A (cg-RX-API-DMAC7.html)
CN (1) CN113271796A (cg-RX-API-DMAC7.html)
AU (1) AU2019374773B2 (cg-RX-API-DMAC7.html)
BR (1) BR112021008767A2 (cg-RX-API-DMAC7.html)
CA (1) CA3118679A1 (cg-RX-API-DMAC7.html)
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CN113271796A (zh) 2018-11-05 2021-08-17 芝加哥大学 用于治疗感染性、自身免疫和过敏性疾病的方法和组合物
WO2022020852A1 (en) * 2020-07-22 2022-01-27 The University Of Chicago Methods and compositions for treating autoimmune and allergic disorders
US11334352B1 (en) 2020-12-29 2022-05-17 Kpn Innovations, Llc. Systems and methods for generating an immune protocol for identifying and reversing immune disease
JP7124148B1 (ja) * 2021-03-08 2022-08-23 Varinos株式会社 微生物叢のメタゲノム解析
EP4426354A4 (en) * 2021-11-03 2025-10-08 Univ Chicago PRODRUG COPOLYMERS AND POLYMERIC MICELLES THEREOF FOR DELIVERY OF SHORT-CHAIN FATTY ACIDS, PROMOTION OF GUT HEALTH, AND TREATMENT OF IMMUNE AND/OR INFLAMMATORY CONDITIONS AND FOOD ALLERGY
WO2025183115A1 (ja) * 2024-02-28 2025-09-04 三菱ケミカル株式会社 乳酸産生菌及び酪酸産生菌を含む整腸用組成物
CN120843703A (zh) * 2025-07-24 2025-10-28 上海市生物医药技术研究院 一种利用癌组织的特定微生物预测乳腺癌原位复发的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0307026D0 (en) * 2003-03-27 2003-04-30 Rowett Res Inst Bacterial supplement
CA2683383C (en) 2007-02-21 2016-01-05 Allaccem, Incorporated Bridged polycyclic compound based compositions for the inhibition and amelioration of disease
ES2993669T3 (en) 2011-12-01 2025-01-03 Univ Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
US20140161878A1 (en) * 2012-12-12 2014-06-12 Sweet Wellness AB Multi-nutrient supplement and uses thereof
US9956282B2 (en) * 2013-12-16 2018-05-01 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
JP6754694B2 (ja) 2014-03-06 2020-09-16 リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル プロバイオティクス製剤および使用のための方法
CA2964480A1 (en) 2014-10-31 2016-05-06 Whole Biome Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
WO2016149687A1 (en) * 2015-03-18 2016-09-22 Whole Biome, Inc. Methods and compositions relating to microbial treatment and diagnosis of skin disorders
CN115252650A (zh) 2015-11-03 2022-11-01 布里格姆及妇女医院股份有限公司 用于治疗和/或预防食物变态反应的治疗性微生物群
EP3639834B1 (en) 2016-02-04 2023-07-12 Universiteit Gent Use of microbial communities for human and animal health
US20200016256A1 (en) 2016-09-22 2020-01-16 The University Of Chicago Immune response modulation using live biotherapeutics, for conditions such as allergy desensitization
WO2018075886A1 (en) 2016-10-21 2018-04-26 The University Of Chicago Compositions and methods for inducing immune system maintenance to prevent and/or treat infections
CA3045026A1 (en) 2016-12-06 2018-06-14 Whole Biome Inc. Methods and compositions relating to isolated and purified microbes
WO2018107365A1 (zh) * 2016-12-13 2018-06-21 深圳华大基因研究院 粪厌氧棒杆菌(Anaerostipes caccae)及其应用
WO2018129249A1 (en) 2017-01-05 2018-07-12 The University Of Chicago Inhibition of enteric infection through the modulation of microbiota
EP3606325B1 (en) * 2017-04-03 2024-09-04 Gusto Global, LLC Rational design of microbial-based biotherapeutics
JP7136807B2 (ja) 2017-04-17 2022-09-13 ザ・ユニバーシティ・オブ・シカゴ ヒトの健康及び疾患の治療用途向けの短鎖脂肪酸の腸への送達用ポリマー材料
CN113271796A (zh) 2018-11-05 2021-08-17 芝加哥大学 用于治疗感染性、自身免疫和过敏性疾病的方法和组合物
ES2763874B2 (es) 2018-11-30 2020-10-13 Consejo Superior Investigacion Phascolarctobacterium faecium para su uso en la prevencion y tratamiento de la obesidad y sus comorbilidades

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WO2020097077A1 (en) 2020-05-14
JP2022510780A (ja) 2022-01-28
EP3876755A4 (en) 2022-08-24
JP7737098B2 (ja) 2025-09-10
CN113271796A (zh) 2021-08-17
BR112021008767A2 (pt) 2021-08-17
US20210386796A1 (en) 2021-12-16
AU2019374773A1 (en) 2021-06-10
US12589122B2 (en) 2026-03-31
EP3876755A1 (en) 2021-09-15
CA3118679A1 (en) 2020-05-14
AU2019374773B2 (en) 2025-10-16

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