KR20210013269A - 3D Customized Nasal Implant Design process - Google Patents

Abstract

A 3D design method of a nasal implant is disclosed. The 3D design method of the nasal implant of the present invention comprises: a segmentation step of segmenting a CT image of a patient′s nose based on the contrast values of human tissues including bones, cartilage, and muscles of the nose; and an implementation step of implementing a 3D object of the nose in the CT image by integrating the contrast values of divided bones, the contrast values of cartilage, and the contrast values of human tissues such as muscles, etc.

Description

3D customized nasal implant design method {3D Customized Nasal Implant Design process}

The present invention relates to a 3D design method of a nasal implant, and more particularly, to a 3D customized nasal implant design method that can implement a nasal implant in 3D based on the contrast values of human tissues such as bones, cartilage and muscles of the nose. About.

The type of rhinoplasty is very diverse, and the type of surgery varies depending on the patient's condition, needs, type of transformation, and the type and method of previous surgery. Rhinoplasty includes a wide range of areas, from simply raising or correcting a curved nose, to correcting congenital anomalies, healing defects caused by accidents, and reconstruction of the nose after removal of cancerous tissue. Among them, apnea can be performed for corrective treatment or cosmetic purposes when there is a birth defect or deformity in the nose area due to a low or deformed nose, or due to tumor surgery.

In general, jungbisurgery is made by inserting materials, and the materials can be divided into grafts and implants.

There are two types of implants: bone and cartilage, and bone can be divided into cartilage bone formed by ossification of cartilage and membranous bone formed by direct ossification of mesenchymal tissue.

In general, membranous bones such as skulls have good survival rates and low absorption rates, so they are often used for autologous bone transplantation, and cartilage bones such as iliac bones and ribs are also used. Cartilage has a lower absorption rate than bone tissue, can survive without blood supply, and is easy to shape. Nasal septal cartilage, ear cartilage and costal cartilage are mainly used for chondrology. In the case of bone grafts among the implants, the bone fusion is firm, so it is not displaced well, and does not cause a foreign body reaction, but it is difficult to obtain a large amount.

However, fractures can occur, the implants are difficult to collect, scars can remain on the donor, difficult to handle, high absorption, and inflexible. Among autologous cartilage, nasal septal cartilage is convenient and good, but it is not in large quantities, and it is difficult to form a solid nasal dorsal line.

The implant refers to an inert artificial material that does not cause chemical changes even if it is placed in a tissue of a living body for a long period of time, and there are types such as silicone implants, Gore-Tex implants, mercilin mesh, and allodym proplast.

On the other hand, conventional augmentation rhinoplasty materials used in rhinoplasty have been produced in standard lengths and heights without considering the size of the nose of individual patients. Therefore, doctors have spent a lot of time designing and sculpting materials according to the specific needs of each patient. Although tissue engineering technology based on conventional stem cell research has shown the possibility to replace damaged tissues and organs while maintaining its own function, the application of tissue engineering technology in plastic surgery is relatively rare. That is, in most cases, the use of suitable materials to achieve the main purpose in plastic surgery is required.

Recently, 3D printing has been applied to various clinical problems, and 3D printing can be used to manufacture a solid scaffold with a 3D shape.However, no previous studies have applied 3D printing to rhinoplasty or nose surgery. Did.

The reason why the nose, which is the No. 1 cosmetic part, is not produced as a customized implant is the bone up to the upper third part of the nose, but the lower 2/3 part is not bone, but the cartilage and the muscle that covers the cartilage. ) Not implemented on. Therefore, it was difficult to produce implants suitable for human tissues such as cartilage and bone.

The above-described technical configuration is a background technique to aid understanding of the present invention, and does not mean a conventional technique widely known in the art to which the present invention belongs.

Korean Registered Patent Publication No. 10-1747326 (Shim Minbo) 2017. 06. 08.

Therefore, the technical problem to be achieved by the present invention is to provide a 3D customized nasal implant design method that can implement a nasal implant in 3D using a threshold value based on the contrast values of human tissues such as nose bones, cartilage, and muscles. Is to do.

According to an aspect of the present invention, a segmentation step of dividing a CT image of a patient's nose using a threshold based on contrast values of human tissues such as bones, cartilage and muscles of the nose; And an implementation step of implementing the contrast values of human tissues such as bones, cartilage, and muscles of the nose into a 3D object, and a design step of designing a design implant based on the implemented 3D object. Can be.

The CT image of the nose may be provided by a hospital.

A design step of designing a designed nose implant based on the CT image implemented in the implementation step may be further included.

The designing step may further include receiving confirmation from a customer, including a hospital.

In the implementation step, a CT image of the nose of an existing patient may be used.

Selecting a contrast value required by an operator from among values classified by using a boundary operation based on the boundary value, and converting it into a stereolithography (STL) file for 3D imaging; Integrating each of the STL files to prepare a 3D object; And designing the patient's nose implant on the 3D object, and outputting the designed STL file.

The embodiments of the present invention can implement a nasal implant that exactly matches human tissues such as bone as well as cartilage, based on the contrast values of human tissues such as bones, cartilage, and muscles of the nose, so that the needs of customers are more accurate and Can be reflected quickly.

In addition, since the implant is accurately matched with the human tissue of the nose, side effects that may occur due to the implant not being accurately matched can be reduced.

1 is a diagram schematically showing a method for designing a 3D customized nose implant according to an embodiment of the present invention.
FIG. 2 is a diagram schematically showing human tissues such as bones, cartilage, and muscles of the nose are implemented on a CT image by the implementation step illustrated in FIG. 1.
FIG. 3 is a diagram schematically illustrating that a nose implant designed in the design stage shown in FIG. 1 is provided on human tissues such as bone and cartilage.
FIG. 4 is a diagram schematically illustrating a nose implant manufactured by the manufacturing method of FIG. 1.
FIG. 5 is a diagram schematically showing that the nasal implant shown in FIG. 4 is accurately aligned with bone, cartilage, and human tissues of the nose.
6 is a view schematically showing that this embodiment can be applied to the forehead, chin, nasolabial folds (PARANASAL), etc. other than the nose.

In order to fully understand the present invention, operational advantages of the present invention, and objects achieved by the implementation of the present invention, reference should be made to the accompanying drawings illustrating preferred embodiments of the present invention and the contents described in the accompanying drawings.

Hereinafter, the present invention will be described in detail by describing a preferred embodiment of the present invention with reference to the accompanying drawings. The same reference numerals shown in each drawing indicate the same members.

1 is a diagram schematically showing a method for designing a 3D customized nasal implant according to an embodiment of the present invention, and FIG. 2 is a human tissue such as bone, cartilage, and muscles of the nose in a CT image according to the implementation step shown in FIG. This is a diagram schematically showing the implementation, and FIG. 3 is a diagram schematically showing that the design nasal implant designed in the design stage shown in FIG. 1 is provided on human tissues such as bone and cartilage, and FIG. 4 is the manufacturing of FIG. It is a diagram schematically showing a nasal implant manufactured by the method, and FIG. 5 is a diagram schematically showing that the nasal implant shown in FIG. 4 is accurately matched on the bone, cartilage and human tissues of the nose, and FIG. 6 is It is a diagram schematically showing that the embodiment can be applied to the forehead, chin, nasolabial folds (PARANASAL), etc. in addition to the nose.

As shown in these figures, the 3D customized nasal implant design method according to the present embodiment includes a CT (computed tomography) image of the nose of the patient, and the contrast of the bones 10, cartilage 30, and muscles 20 of the nose. A segmentation step (S1) of segmenting using a threshold based on the value, and an implementation step of implementing the nose bones 10, cartilage 30, and muscles 20 in a CT image after segmentation ( S2) is provided.

In the segmentation step S1, first, a CT image of the nose is acquired through a CT device, and the CT image of the nose may be acquired through a conventional CT imaging device. In addition, in this embodiment, a CT image of the nose may be received through a customer, for example, a hospital.

In the segmentation step (S1) of the present embodiment, a contrast value of human tissues such as bones and cartilage of the nose may be obtained based on a CT image transmitted from a hospital or stored in a recording medium. Previously, the upper third part of the nose was bone, but the lower part 2/3 was not bone, but the muscle 20 layer covering the cartilage 30 and the cartilage 30, so the design nose shown in FIG. The implant 200 could not be implemented.

However, in this embodiment, if the patient's CT image is thresholded using a slice 2D image, each intensity value can be classified, and these partial values can be used for detailed areas such as cartilage, bone, and muscle. I can express it. That is, the principle of classifying them refers to a task of distinguishing the same values according to the intensity of the pixel using partial 2D images of the CT image.

In the present embodiment, among values classified using a boundary operation, a contrast value required by an operator is selected and converted into a stereolithography (STL) file for 3D imaging. In this embodiment, a shape in which each STL file required for production after conversion is integrated is referred to as a 3D object. Next, the patient's implant is designed on the 3D object, and the designed STL file is output. For reference, the STL file refers to a file format provided to save 3D modeled data as a standard format file.

The present embodiment may further include a design step of designing the design nose implant 200 based on the CT image implemented in the aforementioned implementation step S2.

In this embodiment, the design nose implant 200 manufactured in the design stage may be manufactured according to a request written on a customer's order form.

In addition, in this embodiment, the designed nose implant 200 may be confirmed through a hospital as a customer. If there is a request for correction from the hospital during this verification process, the designed nose implant 200 may be manufactured again through the above-described implementation step (S2).

Furthermore, in the present embodiment, the designed nose implant 200 may be manufactured in 2 to 3 types and provided to a hospital as a customer.

The present embodiment may further include a guideline nasal implant manufacturing step of manufacturing the design nasal implant 200 as a sample.

In this embodiment, the guideline nose implant may be manufactured using a 3D printer or a mold. For example, in this embodiment, the nose implant can be produced by printing a model designed using a 3D printer or printing a skull using a 3D printer, and then directly designing the implant using an epoxy material. .

The present embodiment may further include a manufacturing step of manufacturing the nasal implant 100 from a material containing silicon in the same shape as the guideline nasal implant that has been confirmed by the customer.

In the manufacturing step of the present embodiment, the nose implant 100 may be provided by a manufacturing method including milling or casting.

Hereinafter, it will be briefly described that the nose implant 100 is manufactured by a casting manufacturing method.

First, after kneading the plaster, a step of immersing the guideline nose implant to a certain depth on one side of the kneaded first plaster is performed. At this stage, the guideline nasal implant can be immersed in the first plaster by 2/3. In this embodiment, the gypsum may be a known yellow stone (yellow stone) dough, which can be applied equally to the manufacture of the second plaster.

Next, after kneading the second kneaded gypsum in the same manner as the first kneaded gypsum, a step of covering the first kneaded gypsum may be performed.

Then, it waits until the first and second plasters are completely cured. In this embodiment, the curing time of the first plaster and the second plaster may take about 24 hours.

When curing is complete, either the first or second plaster is separated to remove the guideline nose implant.

After removing the guideline nasal implant, liquid silicone is injected into the gap between the first and second plaster, and then cured again at a certain temperature for a certain period of time. In this embodiment, the above-described constant temperature may be about 160 degrees Celsius, and the curing time may be 1 to 2 hours. In the present embodiment, in addition to liquid silicon, other known materials such as titanium may be injected.

When the above-described curing time has elapsed, the first and second plasters are removed and the nose implant 100 is separated.

The separated nasal implant 100 is trimmed to the same standard as the guideline nasal implant, surface-treated, and then cleaned to finish.

And this embodiment includes a method of manufacturing an implant by milling.

Hereinafter, a method of manufacturing a nose implant by milling will be briefly described. Milling refers to a method of manufacturing by cutting or trimming physical properties such as block-type silicone for a designed nose implant. In addition to milling, it can be manufactured by hand-cutting (carving) by a technician.

Meanwhile, the present embodiment can be applied to manufacturing implants necessary for chin, paranasal, forehead, paranasal, mandible, temple, and malar. 6 schematically shows that this embodiment can be applied to the forehead, chin, and temporal wrinkles in addition to the nose.

As described above, this embodiment converts the CT image of the patient's body into a 3D object shape based on the body's contrast value, and then uses the converted 3D shape as a sample to create a customized implant of physical properties including silicon. By making it possible to provide a virtual design, it is possible to more accurately reflect the customer's request, and smooth communication with the customer is possible, so that the customer's request can be more diversely reflected.

In addition, there is a great advantage in that the side effects of surgery are reduced in that the implants designed in the patient's bones and tissues and the object space are accurately matched, and that individual preferences can be more accurately reflected. In this embodiment, the object space may be defined as a space in which an object exists on a three-dimensional coordinate system on a three-dimensional surface. That is, the space created by the boundary value based on the contrast value is implanted.

As described above, the present invention is not limited to the described embodiments, and it is obvious to those of ordinary skill in the art that various modifications and variations can be made without departing from the spirit and scope of the present invention. Therefore, it should be said that such modifications or variations belong to the claims of the present invention.

10: bone of the nose
20: muscles of the nose
30: ointment for the nose
40: existing implant
100: nose implant
200: Design nose implant

Claims (1)

A segmentation step of dividing the CT image of the patient's nose using thresholding based on the contrast values of human tissues including the bones, cartilage and muscles of the nose;
An implementation step of implementing a human body tissue including the bone, cartilage, and muscle of the nose in the CT image by a worker;
Integrating each of the STL files to prepare a 3D object; And
Designing the patient's nose implant on the 3D object, comprising the step of outputting the designed STL file,
3D customized nose implant design method comprising the step of selecting a contrast value required by an operator from among the values classified using the boundary value based on the boundary value and converting it to a stereolithography (STL) file for 3D imaging .

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