KR20210007380A - Customized scaffold manufacturing method for bone reconstruction - Google Patents

Customized scaffold manufacturing method for bone reconstruction Download PDF

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KR20210007380A
KR20210007380A KR1020190083748A KR20190083748A KR20210007380A KR 20210007380 A KR20210007380 A KR 20210007380A KR 1020190083748 A KR1020190083748 A KR 1020190083748A KR 20190083748 A KR20190083748 A KR 20190083748A KR 20210007380 A KR20210007380 A KR 20210007380A
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image
bone
reconstruction
aggregate
bone reconstruction
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KR102296032B1 (en
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이상화
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가톨릭대학교 산학협력단
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C13/00—Dental prostheses; Making same
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C13/00—Dental prostheses; Making same
    • A61C13/0003—Making bridge-work, inlays, implants or the like
    • A61C13/0004—Computer-assisted sizing or machining of dental prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2803—Bones for mandibular reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30721—Accessories
    • A61F2/30734—Modular inserts, sleeves or augments, e.g. placed on proximal part of stem for fixation purposes or wedges for bridging a bone defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2875—Skull or cranium
    • A61F2002/2889—Maxillary, premaxillary or molar implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30721—Accessories
    • A61F2/30734—Modular inserts, sleeves or augments, e.g. placed on proximal part of stem for fixation purposes or wedges for bridging a bone defect
    • A61F2002/30736—Augments or augmentation pieces, e.g. wedges or blocks for bridging a bone defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A61F2002/30948—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using computerized tomography, i.e. CT scans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A61F2002/30952—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using CAD-CAM techniques or NC-techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A61F2002/3096—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques trimmed or cut to a customised size

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Dentistry (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Geometry (AREA)
  • Manufacturing & Machinery (AREA)
  • Prostheses (AREA)

Abstract

The present invention relates to a method for producing a customized scaffold for bone reconstruction. A method for producing a customized scaffold for bone reconstruction, according to the present invention, comprises the steps of: preparing a bone reconstruction implant that provides a processing material so that a desired shape can be formed by processing; acquiring, from medical image data obtained by a photographing means such as CT, the image of a recipient site for which bone reconstruction is required; and processing the implant for bone reconstruction so as to generate a bone reconstruction body corresponding to the image of the recipient site.

Description

골재건용 맞춤형 스캐폴드 제작 방법{Customized scaffold manufacturing method for bone reconstruction}Customized scaffold manufacturing method for bone reconstruction}

본 발명은 골재건용 맞춤형 스캐폴드 제작 방법에 관한 것으로, 더욱 상세하게는 인체 내 재건이 필요한 골부위에 대한 의료용 이미지로부터 수혜부의 영상 이미지를 획득하고, 그 획득한 수혜부 이미지를 기초로 골재건용 보형물(ex.block bone) 모양을 수술 전 또는 수술 중 가공하여 환자 맞춤형으로 정밀한 골재건을 가능하게 하도록, 공정이 개선된 골재건용 맞춤형 스캐폴드 제작 방법에 관한 것이다. The present invention relates to a method for manufacturing a customized scaffold for bone reconstruction, and more particularly, to obtain an image image of a recipient part from a medical image of a bone part that needs reconstruction in the human body, and an implant for bone reconstruction based on the acquired image of the recipient part. (ex.block bone) It relates to a method of manufacturing a customized scaffold for bone reconstruction with an improved process to enable precise bone reconstruction tailored to the patient by processing the shape before or during surgery.

치과 또는 정형외과 분야의 환부의 골재건은, 치료 효과의 향상을 통한 빠른 회복을 위해 필수적인 부분으로 인식되고 있다. 특히, 종양 등으로 인하여 발생되는 광범위한 환부는, 골재건이 어렵고, 치료 기간이 많이 소요되기 때문에, 치료 효과를 향상시키기 위한 다양한 기술이 연구되고 있다.Bone reconstruction of the affected area in the field of dentistry or orthopedic surgery is recognized as an essential part for rapid recovery through improvement of therapeutic effect. Particularly, for a wide range of affected areas caused by tumors, etc., since bone reconstruction is difficult and a long treatment period is required, various techniques for improving treatment effects have been studied.

이 중, 악골에 대한 치료 또는 골재건을 위한 치료를 위해서 최근 의료 영상기술의 발전과 함께 진보된 스캐폴드가 제작되어 사용되고 있다.Among them, advanced scaffolds have been manufactured and used with recent advances in medical imaging technology for treatment of jaw bone or bone reconstruction.

이와 같이, 의료 영상기술의 발전은 촬영 및 진단 뿐만 아니라 영상자료를 이용한 수술 전 simulation 등과 같은 다양한 응용 기술로도 발전하였다. 이 중에 하나가 영상 데이터를 이용하여 디자인하고 3D printing으로 출력하는 연구들이 활발하게 이루어지고 있다.As such, the development of medical imaging technology has developed into various application technologies such as pre-operative simulation using image data as well as imaging and diagnosis. One of them is actively researching designing using image data and outputting it by 3D printing.

그러나, 이러한 3D 프린팅에 의한 골재건체 생성 방법에 의하면, 3D 프린팅에 의해 생성된 출력물을 인체에 사용하기까지 여러 가지 임상실험과 장기적 추적 관찰이 필요하여 바로 손쉽게 임상에 적용하기에는 제한이 있으며, 수술 전 simulation 기법에 의해 확보된 출력물이 수술 중 수혜부에 들어맞지 않게 되는 경우에는 골재건 수술을 중단하고 재수술을 하여야 하는 문제가 야기될 수 있다. However, according to this 3D printing method of generating aggregate reconstruction, various clinical trials and long-term follow-up are required before the output generated by 3D printing can be used on the human body. If the output obtained by the simulation technique does not fit into the beneficiary part during surgery, it may cause a problem that the bone reconstruction surgery must be stopped and reoperation must be performed.

대한민국 공개특허공보 공개번호 제2019-0050352호Republic of Korea Patent Publication Publication No. 2019-0050352 대한민국 등록특허공보 등록번호 제1853297호Korean Registered Patent Publication Registration No. 1853297

본 발명은 상기와 같은 문제점을 해결하기 위해 안출된 것으로, 본 발명의 목적은 환자의 골재건이 요구되는 수혜부를, 환자의 의료 영상 데이터를 기초로 밀링 가공하여 형성시킴으로써, 수술 전 미리 골재건체를 성형할 수 있게 함은 물론, 수술 도중에 추가 성형이 필요한 경우에도 추가 가공에 의해 실시간으로 환자 맞춤형으로 골재건체를 성형할 수 있게 하는 골재건용 맞춤형 스캐폴드 제작 방법을 제공하고자 하는 것이다.The present invention was conceived to solve the above problems, and an object of the present invention is to form a beneficiary part requiring bone reconstruction of a patient by milling based on the patient's medical image data, thereby forming a rebuilt aggregate in advance before surgery. In addition, it is intended to provide a method of manufacturing a customized scaffold for bone reconstruction that enables the reconstruction of a patient to be customized in real time by additional processing even when additional molding is required during surgery.

본 발명의 다른 목적은 골재건이 요구되는 수혜부 이미지를 미리 준비된 골재건용 보형물에 투영시켜 그 투영된 이미지를 보면서 실시간으로 가공할 수 있게 하여 정밀한 스캐폴드 제작을 가능하게 하는 골재건용 맞춤형 스캐폴드 제작 방법을 제공하고자 하는 것이다.Another object of the present invention is a method for producing a customized scaffold for aggregate reconstruction that enables precise scaffold fabrication by projecting an image of a beneficiary part requiring aggregate reconstruction onto a pre-prepared implant for bone reconstruction and processing it in real time while viewing the projected image. Is to provide.

상기 목적을 달성하기 위한 본 발명에 의한 골재건용 맞춤형 스캐폴드 제작 방법은, 가공에 의해 원하는 모양을 성형할 수 있도록, 가공재료를 제공하는 골재건용 보형물을 준비하는 단계; CT와 같은 촬영 수단으로부터 얻어진 의료 영상 데이터로부터 골재건이 필요한 수혜부의 영상 이미지를 획득하는 단계; 및 상기 골재건용 보형물을 가공하여 상기 수혜부의 영상 이미지에 대응되는 골재건체를 생성하는 단계;를 포함하여 이루어지는 것을 특징으로 한다.A method for producing a customized scaffold for aggregate reconstruction according to the present invention for achieving the above object comprises the steps of preparing an implant for rebuilding an aggregate providing a processing material so that a desired shape can be formed by processing; Obtaining an image image of a recipient portion requiring bone reconstruction from medical image data obtained from an imaging means such as CT; And generating an aggregate reconstructed body corresponding to the image image of the recipient part by processing the implant for reconstructing the aggregate.

본 발명은, 상기 수혜부의 영상 이미지를 골재건용 보형물에 투영시켜서 그 투영된 이미지를 밀링 가공에 의해 형성하여 상기 골재건체를 생성시킬 수 있도록 구성되는 것이 바람직하다. In the present invention, it is preferable that the image image of the recipient portion is projected onto an implant for bone reconstruction, and the projected image is formed by milling to generate the rebuilt aggregate.

상기 수혜부는 치조골 형상이고, 상기 골재건체는 상기 치조골에 식립되는 임플란트일 수 있다. The beneficiary portion has an alveolar bone shape, and the bone reconstruction body may be an implant to be placed in the alveolar bone.

상기 수혜부는 악골 시술시 절개됨으로써 형성된 골결손부에 해당하는 부분이고, 상기 골재건체는 상기 골결손부에 채워지는 지지체인 것도 가능하다.The beneficiary part is a part corresponding to a bone defect formed by incision during a jaw procedure, and the bone reconstruction body may be a support body filled with the bone defect.

상기 수혜부는 기타 뼈 시술 시 관찰되는 수복이 필요한 골 결손부에 해당할 수 있고, 상기 골재건체는 상기 골 결손부에 채워지는 지지체일 수도 있다. The beneficiary part may correspond to a bone defect that requires repair observed during other bone procedures, and the bone reconstruction body may be a support filled with the bone defect.

상기 수혜부의 영상 이미지는, 수술 전 획득한 1차 이미지와, 수술 도중 획득한 2차 이미지를 포함하여 이루어지고, 상기 골재건체를 생성하는 단계는, 상기 수술 전 획득한 1차 이미지를 이용하여 1차 가공체를 획득하고, 시술 도중 획득한 상기 골결손부에 관한 2차 이미지를 이용하여 상기 1차 가공체로부터 2차 가공체를 얻는 단계;를 포함하여 이루어지는 것도 가능하다.The image image of the recipient part includes a first image acquired before surgery and a second image acquired during surgery, and the step of generating the bone reconstruction is performed by using the first image acquired before the surgery. It is also possible to include a step of obtaining a primary processed body and obtaining a secondary processed body from the primary processed body by using the secondary image of the bone defect obtained during the procedure.

상술한 바와 같은 구성을 가지는 본 발명에 의한 골재건용 맞춤형 스캐폴드 제작 방법은, 환자의 의료 영상 데이터로부터 확보된 수혜부에 관한 영상 이미지를 기초로 하여 골재건용 보형물과 같은 모재를 밀링 가공하는 것에 의해 환자 맞춤형 골재건체를 형성할 수 있도록 구성됨으로써, 3D 프린팅 방식에 의한 성형시 초래되는 재질의 제약없이 기활용되고 있는 다양한 골재건용 재료를 활용할 수 있게 하고, 이러한 골재건용 재료로 수술 전 미리 골재건체를 성형할 수 있게 함은 물론, 수술 도중에 추가 성형이 필요한 경우에도 가공에 의해 실시간으로 환자 맞춤형으로 골재건체를 성형할 수 있게 하는 효과를 가진다.The method of manufacturing a customized scaffold for bone reconstruction according to the present invention having the configuration as described above is by milling a base material such as an implant for bone reconstruction based on the image image of the recipient part obtained from the patient's medical image data. By being configured to form patient-customized aggregate reconstruction, it is possible to utilize various materials for reconstruction of bones that are already used without restrictions on the material caused during molding by 3D printing method, and use these materials for reconstruction of aggregates before surgery. In addition to making it possible to mold, it has the effect of making it possible to shape the aggregate reconstruction body tailored to the patient in real time by processing even when additional molding is required during surgery.

도 1은 본 발명의 일실시예에 따른 골재건용 맞춤형 스캐폴드 제작 방법의 구성을 설명하기 위한 블럭도.
도 2는 본 발명 일실시예의 적용예를 설명하기 위한 도면.
도 3은 본 발명 일실시예의 구현을 위해 채용된 영상 투영 및 이를 이용한 골재건체 성형 과정을 설명하기 위한 도면.
도 4는 본 발명 일실시예의 다른 적용예를 설명하기 위한 도면.
도 5는 본 발명 일실시예의 다른 적용예에서의 프로세스를 설명하기 위한 도면.
도 6은 본 발명 일실시예의 또 다른 적용예를 설명하기 위한 블록도.
도 7은 도 6에 도시된 적용예 설명을 위한 참고도.1 is a block diagram for explaining the configuration of a method of manufacturing a customized scaffold for aggregate reconstruction according to an embodiment of the present invention.
Figure 2 is a view for explaining an application example of an embodiment of the present invention.
Figure 3 is a view for explaining the image projection adopted for the implementation of an embodiment of the present invention and a process of forming an aggregate structure using the same.
4 is a view for explaining another application example of the embodiment of the present invention.
5 is a view for explaining a process in another application example of an embodiment of the present invention.
6 is a block diagram for explaining another application example of an embodiment of the present invention.
7 is a reference diagram for explaining the application example shown in FIG. 6.

이하의 설명에서 본 발명에 대한 이해를 명확히 하기 위하여, 본 발명의 특징에 대한 공지의 기술에 대한 설명은 생략하기로 한다. 이하의 실시 예는 본 발명의 이해를 돕기 위한 상세한 설명이며, 본 발명의 권리 범위를 제한하는 것이 아님은 당연할 것이다. 따라서, 본 발명과 동일한 기능을 수행하는 균등한 발명 역시 본 발명의 권리 범위에 속할 것이다.In the following description, in order to clarify an understanding of the present invention, a description of known techniques for the features of the present invention will be omitted. The following embodiments are detailed descriptions to aid understanding of the present invention, and it will be natural that the scope of the present invention is not limited. Accordingly, an equivalent invention that performs the same function as the present invention will also fall within the scope of the present invention.

그리고, 이하의 설명에서 동일한 식별 기호는 동일한 구성을 의미하며, 불필요한 중복적인 설명 및 공지 기술에 대한 설명은 생략하기로 한다. 또한, 상기 발명의 배경이 되는 기술에 대한 기재 내용과 중복되는 이하의 본 발명의 각 실시예에 관한 설명 역시 생략하기로 한다.And, in the following description, the same identification symbols mean the same configuration, and unnecessary redundant descriptions and descriptions of known technologies will be omitted. In addition, descriptions of each of the embodiments of the present invention will be omitted below overlapping with the description of the technology that is the background of the present invention.

이하에서는 본 발명의 일실시예에 따른 골재건용 맞춤형 스캐폴드 제작 방법을 첨부된 도면을 참조하여 상세히 설명하기로 한다.Hereinafter, a method of manufacturing a customized scaffold for aggregate reconstruction according to an embodiment of the present invention will be described in detail with reference to the accompanying drawings.

도 1은 본 발명의 일실시예에 따른 골재건용 맞춤형 스캐폴드 제작 방법의 구성을 설명하기 위한 블럭도이고, 도 2는 본 발명 일실시예의 적용예를 설명하기 위한 도면이며, 도 3은 본 발명 일실시예의 구현을 위해 채용된 영상 투영 및 이를 이용한 골재건체 성형 과정을 설명하기 위한 도면이다. 1 is a block diagram for explaining the configuration of a method of manufacturing a customized scaffold for reconstruction according to an embodiment of the present invention, Figure 2 is a view for explaining an application example of the present invention, Figure 3 is the present invention It is a view for explaining the image projection adopted for the implementation of the embodiment and the process of forming an aggregate reconstruction body using the same.

이들 도면에 도시된 바와 같이, 본 발명의 일실시예에 따른 골재건용 맞춤형 스캐폴드 제작 방법은, 골재건용 보형물을 준비하는 단계(S10)와 수혜부의 영상 이미지를 획득하는 단계(S20)와 골재건체를 생성하는 단계(S30)를 포함하여 이루어진다.As shown in these drawings, the method of manufacturing a customized scaffold for bone reconstruction according to an embodiment of the present invention includes the steps of preparing an implant for bone reconstruction (S10) and obtaining an image image of the recipient (S20) and It comprises a step of generating (S30).

상기 골재건용 보형물(3)은, 골재건이 요구되는 수혜부에 식립될 골재건체를 만들기 위한 모재인 것으로, 예컨대 Block bone graft 시술시 요구되는 block bone이나 기타 밀링 가공에 의해 원하는 모양을 성형할 수 있는 골재건용 재료(ex.티타늄)를 포함한다. The bone reconstruction implant (3) is a base material for making an aggregate reconstruction body to be placed in the beneficiary part where bone reconstruction is required, and for example, it is possible to shape a desired shape by block bone or other milling processing required during a block bone graft procedure. Includes aggregate reconstruction materials (ex. titanium).

본 실시예는 이러한 골재건용 보형물(3)을 수술 전 미리 준비하여 수술 전 또는 수술 도중 상기 준비된 골재건용 보형물(3)을 밀링 가공함으로써 요구되는 골재건체를 성형할 수 있는 것이다. In this embodiment, the bone reconstruction prosthesis 3 may be prepared before surgery and the prepared bone reconstruction prosthesis 3 may be milled before or during the operation to form the required bone reconstruction.

상기 수혜부의 영상 이미지를 획득하는 단계는 CT와 같은 촬영 수단으로부터 얻어진 의료 영상 데이터로부터 골재건이 필요한 수혜부의 영상 이미지(1)(2)를 획득하게 된다. In the step of acquiring the image image of the recipient part, an image image (1) (2) of the recipient part in need of bone reconstruction is acquired from medical image data obtained from an imaging means such as CT.

상기 촬영 수단은 CT 뿐만 아니라 X-ray 등 의료용으로 활용되는 다양한 영상 촬영 장치를 포함하고, 상기 수혜부에 관한 영상 이미지는 이러한 촬영 장치에 의해 획득한 영상 이미지(1) 또는 보정된 이미지(2)를 포함한다.The imaging means includes various imaging devices that are used for medical purposes such as X-ray as well as CT, and the image image of the recipient is an image image (1) or a corrected image (2) acquired by such an imaging device. Includes.

상기 골재건체를 생성하는 단계는, 미리 준비된 혹은 수술 과정에서 확보된 골재건용 보형물(3)을 밀링 가공하여 상기 수혜부의 영상 이미지(1)(2)에 대응되는 골재건체를 생성한다. In the step of generating the reconstructed aggregate, an aggregate reconstructed body corresponding to the image image (1) and (2) of the recipient portion is generated by milling the prosthesis 3 prepared in advance or secured during the surgical procedure.

이러한 구성을 가지는 본 실시예에 따른 골재건용 맞춤형 스캐폴드 제작 방법은, 도 2에 잘 도시된 바와 같이, CT와 같은 촬영 수단에 의해 환자의 의료 영상 데이터를 확보(a)하고 이러한 의료 영상 데이터로부터 발치 후 형성되는 가상의 발치와에 관한 영상을 확보(b)한 이후, 이러한 영상으로부터 상기 발치와(수혜부)에 식립될 임플란트 이미지를 획득한 다음, 최종적으로 얻어진 수혜부의 영상 이미지(1)(2)를 기초로 준비된 골재건용 보형물(3)을 밀링 가공(c)하여 원하는 골재건체를 만들어 낼 수 있는 것이다. In the method of manufacturing a customized scaffold for bone reconstruction according to this embodiment having such a configuration, as well as shown in FIG. 2, the medical image data of the patient is secured (a) by an imaging means such as CT, and from the medical image data After securing (b) an image of a virtual tooth decay formed after tooth extraction, an implant image to be placed in the tooth extraction follicle (beneficiary part) is obtained from this image, and the image image of the recipient part finally obtained (1) ( By milling (c) the implant (3) for bone reconstruction prepared on the basis of 2), it is possible to create the desired aggregate rebuild body.

이와 같이, 본 실시예에 따른 골재건용 맞춤형 스캐폴드 제작 방법은, 환자의 의료 영상 데이터로부터 확보된 수혜부에 관한 영상 이미지를 기초로 하여 골재건용 보형물(3)과 같은 모재를 밀링 가공하는 것에 의해 환자 맞춤형 골재건체를 형성할 수 있도록 구성됨으로써, 3D 프린팅 방식에 의한 성형시 초래되는 재질의 제약없이 기활용되고 있는 다양한 골재건용 재료를 활용할 수 있게 하고, 이러한 골재건용 재료로 수술 전 미리 골재건체를 성형할 수 있게 함은 물론, 수술 도중에 추가 성형이 필요한 경우에도 밀링 가공에 의해 실시간으로 환자 맞춤형으로 골재건체를 성형할 수 있게 하는 장점을 기대할 수 있게 한다. As described above, the method of manufacturing a customized scaffold for bone reconstruction according to the present embodiment is performed by milling a base material such as the bone reconstruction implant 3 based on the image image of the recipient part obtained from the patient's medical image data. By being configured to form patient-customized aggregate reconstruction, it is possible to utilize various materials for reconstruction of bones that are already used without restrictions on the material caused during molding by 3D printing method, and use these materials for reconstruction of aggregates before surgery. In addition to making it possible to shape, it is possible to expect the advantage of being able to shape the aggregate reconstruction body tailored to the patient in real time by milling even when additional molding is required during surgery.

한편, 본 실시예는, 수혜부에 식립될 골재건체를, 상기 확보된 영상 이미지에 관한 데이터를 예컨대 의료용 CNC 장치의 제어부에 입력하고 상기 제어부의 제어신호에 기초하여 자동으로 수술 전 미리 밀링 가공하여 생성할 수 있도록 구성될 수도 있으나, 도 3에 잘 도시된 바와 같이, 상기 수혜부의 영상 이미지(1)(2)를 골재건용 보형물(3)에 투영시켜서 그 투영된 이미지를 이용하여 수작업에 의해 실시간으로 생성시킬 수 있도록 구성되는 것도 가능하다. On the other hand, in this embodiment, the bone reconstruction body to be placed in the beneficiary part is automatically milled before surgery based on the control signal of the medical CNC device and inputs the data related to the secured image to the control unit of the medical CNC device. Although it may be configured to be able to generate, as well as shown in FIG. 3, the image image (1) (2) of the recipient is projected onto the implant for bone reconstruction (3), and the projected image is used in real time by hand. It is also possible to be configured so that it can be created with.

도면 중 미설명 부호 C는 상기 CNC 장치의 제어부의 제어신호에 기초하여 구동되는 가공팁(4)이다. In the drawings, reference numeral C denotes a machining tip 4 that is driven based on a control signal from a control unit of the CNC device.

그리고, 상기 수혜부는 예컨대 임플란트가 식립될 치조골에 해당하는 부분이고, 상기 골재건체는 상기 치조골에 식립되는 임플란트이나, 본 발명은 반드시 이에 한정되지 않는다. In addition, the beneficiary portion is, for example, a portion corresponding to the alveolar bone in which an implant is to be placed, and the bone reconstruction body is an implant that is placed in the alveolar bone, but the present invention is not necessarily limited thereto.

예컨대, 도 4 및 도 5에 잘 도시된 바와 같이, 상기 수혜부는 악골 시술시 절개됨으로써 형성된 골결손부에 해당하는 부분이고, 상기 골재건체는 상기 골결손부에 채워지는 지지체인 것도 가능하다.For example, as well illustrated in FIGS. 4 and 5, the beneficiary part is a part corresponding to a bone defect formed by incision during a jaw procedure, and the bone reconstruction body may be a support filled with the bone defect.

도 4는 본 발명 일실시예의 다른 적용예를 설명하기 위한 도면이고, 도 5는 본 발명 일실시예의 다른 적용예에서의 프로세스를 설명하기 위한 도면이다.FIG. 4 is a view for explaining another application example of an embodiment of the present invention, and FIG. 5 is a view for explaining a process in another application example of the embodiment of the present invention.

도 4에 잘 도시된 바와 같이, 일반적으로 돌출턱은 악골의 일부를 제거하는 수술을 통해 올바르게 교정될 수 있다. As shown well in Figure 4, in general, the protruding jaw can be corrected correctly through surgery to remove a part of the jaw.

이러한 악골 교정 수술 과정에서는, 도 5의 (a)에 도시된 제거될 부분이 정확하여 제거 이후 나머지 뼈 부위들이 서로 골결손부 없이 접합될 수도 있으나, 도 5의 (b)와 같이 상기 나머지 뼈 부위들 사이에 골결손부가 발생하는 경우가 종종 발생하게 된다. In this jaw correction surgery process, the portion to be removed shown in FIG. 5 (a) is accurate, so that the remaining bone portions may be joined to each other without bone defects, but the remaining bone portions as shown in FIG. 5 (b) Bone defects often occur between them.

이 경우 상기 수혜부의 영상 이미지는, 수술 전 획득한 1차 이미지(5)(상기 제거대상 부분)와, 수술 도중 획득한 2차 이미지(6)(상기 골결손부에 해당하는 부분)를 포함하여서, 상기 수혜부의 영상 이미지를 획득하는 단계는 상기 1차 이미지(5)와 2차 이미지(6)를 획득하는 과정을 포함하여 이루어진다. In this case, the image image of the recipient includes a primary image 5 (the part to be removed) acquired before surgery, and a secondary image 6 acquired during surgery (a part corresponding to the bone defect). , Acquiring the image image of the recipient includes a process of acquiring the primary image 5 and the secondary image 6.

그리고, 상기 골재건체를 생성하는 단계는, 도 5의 (c)와 같이, 상기 수술 전 획득한 1차 이미지(5)를 이용하여 1차 가공체(50)를 획득하고, 도 5의 (d)와 같이, 시술 도중 획득한 상기 골결손부에 관한 2차 이미지(6)를 이용하여 상기 1차 가공체(50)로부터 2차 가공체(60)를 얻게 된다. And, the step of generating the aggregate reconstruction, as shown in Figure 5 (c), by using the first image (5) obtained before the surgery to obtain the primary processed body 50, and Figure 5 (d) ), a secondary processed body 60 is obtained from the primary processed body 50 by using the secondary image 6 of the bone defect obtained during the procedure.

이러한 구성을 가지는 본 실시예는, 수술 전 확보된 수혜부의 영상 이미지(5)로부터 악골의 제거대상 이미지를 확정하여 수술 도중 그 제거대상인 1차 가공체(50)를 획득(도 1의 c)하고, 수술 도중 발생한 악골 골결손부에 관한 이미지(6)를 실시간으로 확보한 다음, 상기 1차 가공체(50) 또는 기초재료(7)로부터 2차 가공체(60)를 생성(도 5의 d)한 후, 그 2차 가공체(60)로 상기 골결손부를 메울 수 있게 함으로써(도 5의 e), 수술 도중 발생할 수 있는 골재건체의 부정합 현상을 방지할 수 있게 되고, 실시간으로 정확한 골재건을 가능하게 하는 장점을 기대할 수 있게 한다. In this embodiment having such a configuration, by determining an image to be removed of the jaw from the image image 5 of the recipient part secured before the operation, the primary processed body 50 as the object to be removed during the operation is obtained (Fig. 1 c), and , After obtaining the image (6) of the jaw bone defect generated during the operation in real time, and then creating a secondary processed body 60 from the primary processed body 50 or the basic material 7 (Fig. 5 d After), by allowing the bone defect to be filled with the secondary processed body 60 (Fig. 5 e), it is possible to prevent misalignment of the bone reconstruction body that may occur during surgery, and accurate bone reconstruction in real time. You can expect the advantages that make it possible.

한편, 도 6은 본 발명 일실시예의 또 다른 적용예를 설명하기 위한 블록도이고, 도 7은 도 6에 도시된 적용예 설명을 위한 참고도이다.Meanwhile, FIG. 6 is a block diagram for explaining another application example of an embodiment of the present invention, and FIG. 7 is a reference diagram for explaining the application example shown in FIG. 6.

이들 도면에 잘 도시된 바와 같이, 본 실시예는 도 4 및 도 5에 도시된 적용예와 마찬가지로, 수술 전 획득한 수혜부의 1차 영상 이미지를 이용하여 1차 가공체를 획득하고(S20'), 수술 도중 카메라(휴대폰 카메라 포함)와 같은 촬영수단에 의해 얻어진 2차 영상 이미지를 획득한 후, 그 2차 영상 이미지와 상기 1차 가공체를 중첩하여 실시간으로 관찰하면서 상기 수혜부 모양에 맞게 2차 가공체를 획득(S30')할 수 있도록 구성된다. As well as shown in these drawings, this embodiment acquires a primary processed body using the primary image image of the recipient part acquired before surgery, similar to the application examples shown in FIGS. 4 and 5 (S20') , After acquiring a secondary image image obtained by a photographing means such as a camera (including a mobile phone camera) during surgery, the secondary image image and the primary processed object are superimposed and observed in real time to fit the shape of the recipient part. It is configured to be able to obtain a processed vehicle (S30').

이러한 구성을 가지는 본 실시예는 수술시 실시간으로 결손부 모양을 확인하면서 그 결손부에 식립된 골재건체를 형성할 수 있게 하여, 부작용이 없고 2차 수술이 필요없는 정확한 골재건을 가능하게 한다. This embodiment having such a configuration makes it possible to form an bone reconstructive body implanted in the defective portion while checking the shape of the defect in real time during surgery, thereby enabling accurate bone reconstruction without side effects and requiring no secondary surgery.

이상 본 발명의 다양한 실시예에 대하여 설명하였으나, 본 실시예 및 본 명세서에 첨부된 도면은 본 발명에 포함되는 기술적 사상의 일부를 명확하게 나타내고 있는 것에 불과하며, 본 발명의 명세서 및 도면에 포함된 기술적 사상의 범위 내에서 당업자가 용이하게 유추할 수 있는 변형 예와 구체적인 실시예는 모두 본 발명의 권리범위에 포함되는 것이 자명하다고 할 것이다.Although various embodiments of the present invention have been described above, the present embodiment and the accompanying drawings are merely illustrative of some of the technical ideas included in the present invention, and are included in the specification and drawings of the present invention. It will be apparent that all modified examples and specific embodiments that can be easily inferred by a person skilled in the art within the scope of the technical idea are included in the scope of the present invention.

1,2:수혜부의 영상 이미지 3:골재건용 보형물
4:가공팁 5:1차 이미지
50:1차 가공체 6:2차 이미지
60:2차 가공체 7:기초재료1,2: Image of the recipient's image 3: Implants for bone reconstruction
4: Processing tip 5: 1st image
50: 1st processed body 6: 2nd image
60: secondary processed body 7: basic material

Claims (6)

가공에 의해 원하는 모양을 성형할 수 있도록, 가공재료를 제공하는 골재건용 보형물을 준비하는 단계;
CT 또는 카메라와 같은 촬영 수단으로부터 얻어진 의료 영상 데이터로부터 골재건이 필요한 수혜부의 영상 이미지를 획득하는 단계; 및
상기 골재건용 보형물을 가공하여 상기 수혜부의 영상 이미지에 대응되는 골재건체를 생성하는 단계;를 포함하여 이루어지는 것을 특징으로 하는 골재건용 맞춤형 스캐폴드 제작 방법.Preparing an implant for reconstruction of an aggregate providing a processing material so that a desired shape can be formed by processing;
Obtaining an image image of a recipient portion requiring bone reconstruction from medical image data obtained from imaging means such as CT or a camera; And
The method of manufacturing a customized scaffold for bone reconstruction, comprising: processing the implant for reconstruction to generate an aggregate reconstruction body corresponding to the image image of the recipient. 제1항에 있어서,
상기 수혜부의 영상 이미지를 골재건용 보형물에 투영시켜서 그 투영된 이미지를 밀링 가공에 의해 형성하여 상기 골재건체를 생성시키는 것을 특징으로 하는 골재건용 맞춤형 스캐폴드 제작 방법.The method of claim 1,
The method for producing a customized scaffold for bone reconstruction, characterized in that the image image of the recipient part is projected onto an implant for bone reconstruction, and the projected image is formed by milling to generate the rebuilt aggregate. 제1항에 있어서,
상기 수혜부는 치조골 형상이고, 상기 골재건체는 상기 치조골에 식립되는 임플란트인 것을 특징으로 하는 골재건용 맞춤형 스캐폴드 제작 방법.The method of claim 1,
The method of manufacturing a customized scaffold for bone reconstruction, characterized in that the beneficiary part has an alveolar bone shape, and the bone reconstruction body is an implant that is placed in the alveolar bone. 제1항에 있어서,
상기 수혜부는 악골 시술시 절개됨으로써 형성된 골결손부에 해당하는 부분이고, 상기 골재건체는 상기 골결손부에 채워지는 지지체인 것을 특징으로 하는 골재건용 맞춤형 스캐폴드 제작 방법.The method of claim 1,
The beneficiary part is a part corresponding to a bone defect formed by incision during a jaw procedure, and the bone reconstruction body is a support body filled with the bone defect. 제4항에 있어서,
상기 수혜부의 영상 이미지는, 수술 전 획득한 1차 이미지와, 수술 도중 획득한 2차 이미지를 포함하여 이루어지고,
상기 골재건체를 생성하는 단계는, 상기 수술 전 획득한 1차 이미지를 이용하여 1차 가공체를 획득하고, 시술 도중 획득한 상기 골결손부에 관한 2차 이미지를 이용하여 상기 1차 가공체로부터 2차 가공체를 얻는 단계;를 포함하여 이루어지는 것을 특징으로 하는 골재건용 맞춤형 스캐폴드 제작 방법.The method of claim 4,
The image image of the recipient part includes a primary image acquired before surgery and a secondary image acquired during surgery,
The step of generating the reconstructed bone may include obtaining a primary processed body using the primary image acquired before the surgery, and using a secondary image of the bone defect obtained during the procedure from the primary processed body. A method for producing a customized scaffold for aggregate reconstruction, comprising: obtaining a secondary processed body. 제5항에 있어서,
상기 2차 가공체를 얻는 단계는 카메라와 같은 촬영수단에 의해 얻어진 상기 2차 이미지와 상기 1차 가공체를 중첩시킨 후 실시간으로 관찰하면서 상기 결손부에 적합한 모양의 가공체를 얻는 것을 특징으로 하는 골재건용 맞춤형 스캐폴드 제작 방법.The method of claim 5,
In the step of obtaining the secondary processed body, the secondary image obtained by a photographing means such as a camera and the primary processed body are superimposed and observed in real time to obtain a processed body having a shape suitable for the defect. How to make custom scaffolds for aggregate reconstruction.
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101175822B1 (en) * 2004-02-20 2012-08-24 부트벨딩 아게 Implant that can be implanted in osseous tissue, method for producing said implant and corresponding implant
KR20160024894A (en) * 2016-02-16 2016-03-07 최병억 System for designing customized nasal implant
KR20160078093A (en) * 2014-12-24 2016-07-04 주식회사 메가젠임플란트 System for forming 3 dimensional object and its method
KR101853297B1 (en) 2016-06-14 2018-05-02 연세대학교 산학협력단 Fabrication system for an ear implant and a method for fabricating the ear implant
KR20190050352A (en) 2017-11-03 2019-05-13 울산대학교 산학협력단 Method and apparatus for generating 3d model data for manufacturing of implant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101137991B1 (en) * 2009-09-30 2012-04-20 전남대학교산학협력단 Fabrication and manufacturing method of image based patient specific spinal implant
US10610299B2 (en) * 2011-12-14 2020-04-07 Stryker European Holdings I, Llc Technique for generating a bone plate design
CA2954679C (en) * 2014-07-10 2020-07-21 Mohamed R. Mahfouz Bone reconstruction and orthopedic implants
US10098715B2 (en) * 2015-06-24 2018-10-16 Dental Imaging Technologies Corporation Generating a design for a dental restorative product from dental images

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101175822B1 (en) * 2004-02-20 2012-08-24 부트벨딩 아게 Implant that can be implanted in osseous tissue, method for producing said implant and corresponding implant
KR20160078093A (en) * 2014-12-24 2016-07-04 주식회사 메가젠임플란트 System for forming 3 dimensional object and its method
KR20160024894A (en) * 2016-02-16 2016-03-07 최병억 System for designing customized nasal implant
KR101853297B1 (en) 2016-06-14 2018-05-02 연세대학교 산학협력단 Fabrication system for an ear implant and a method for fabricating the ear implant
KR20190050352A (en) 2017-11-03 2019-05-13 울산대학교 산학협력단 Method and apparatus for generating 3d model data for manufacturing of implant

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
작업지원을 위한 정보표시와 화상계측, 인터넷 기사* *

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