KR20210006574A - Disposable drug delivery patch detachable iontophoresis device - Google Patents

Disposable drug delivery patch detachable iontophoresis device Download PDF

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KR20210006574A
KR20210006574A KR1020190082360A KR20190082360A KR20210006574A KR 20210006574 A KR20210006574 A KR 20210006574A KR 1020190082360 A KR1020190082360 A KR 1020190082360A KR 20190082360 A KR20190082360 A KR 20190082360A KR 20210006574 A KR20210006574 A KR 20210006574A
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drug delivery
delivery patch
disposable drug
iontophoresis device
battery
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Korean (ko)
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오경진
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오경진
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Electrotherapy Devices (AREA)

Abstract

The present invention relates to an iontophoresis device that is easily attached to the top of a disposable drug delivery patch to improve drug delivery efficiency of the disposable drug delivery patch and to pursue convenience in product use. The iontophoresis device with the detachable disposable drug delivery patch according to the present invention includes: a battery unit including a battery housing and a battery for supplying electrical energy; an electrode unit including a first electrically conductive layer and a second electrically conductive layer electrically connected to positive (+) and negative (-) poles of the battery of the battery unit, respectively; and a connection unit that can be easily detached from the top of the disposable drug delivery patch.

Description

일회용 약물 전달 패치 탈부착형 이온토포레시스 장치{Disposable drug delivery patch detachable iontophoresis device}Disposable drug delivery patch detachable iontophoresis device TECHNICAL FIELD

본 발명은 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치에 관한 것으로서, 더욱 상세하게는 일회용 약물 전달 패치의 상부에 부착되어 전지로부터 전력에너지를 공급받아 일회용 약물 전달 패치의 약물 전달 효율을 향상시킬 수 있도록 한 이온토포레시스 장치에 관한 것이다.The present invention relates to a disposable drug delivery patch detachable iontophoresis device, and more particularly, it is attached to the top of the disposable drug delivery patch to receive power energy from a battery to improve the drug delivery efficiency of the disposable drug delivery patch. It relates to an iontophoresis device.

종래 미용, 의료 목적의 약물전달을 위한 이온토포레시스 장치는 크게 전기에너지를 공급하는 전지를 포함하는 전지부와 활성물질과 약물을 포함한 하이드로겔, 부직포 등의 담체로 구성된 활성물질 함유층이 일체화되거나 활성물질 함유층이 전지부와 별개로 구성되어 있다. 전자의 경우에는 새로운 약물, 활성물질의 전달 효율을 향상시키기 위해서, 새로운 장치를 고안하여 사용해야 한다는 불편한 점이 있으며, 후자의 경우에는 활성물질이 고정화되어 있지 않고 피부에 직접 도포되어, 약물 전달 효율이 낮아지고 끈적함, 이물감 등으로 인하여 사용감이 떨어지는 문제점을 안고 있었다. Conventional iontophoresis devices for drug delivery for cosmetic and medical purposes are largely integrated with a battery unit including a battery that supplies electric energy and an active material-containing layer composed of a carrier such as hydrogel containing active substances and drugs, and nonwoven fabrics. The active material-containing layer is configured separately from the battery part. In the former case, in order to improve the delivery efficiency of new drugs and active substances, it is inconvenient to devise and use a new device, and in the latter case, the active substance is not immobilized and is applied directly to the skin, resulting in low drug delivery efficiency. There was a problem that the feeling of use was deteriorated due to the feeling of stickiness and foreign body.

한국특허 10-0610252(2006.08.01 등록)Korean Patent 10-0610252 (registered on August 1, 2006) 한국특허 10-0730582(2007.06.14 등록)Korean patent 10-0730582 (registered on June 14, 2007)

본 발명은 상기와 같은 문제점을 해결하기 위해 창안된 것으로서, 일회용 약물 전달 패치의 상부에 쉽게 탈부착될 수 있도록 하여 약물 전달 효율을 향상시키고 추구할 수 있도록 한 이온토포레시스 장치를 제공하는 데 그 목적이 있다.The present invention has been invented to solve the above problems, and is to provide an iontophoresis device capable of improving and pursuing drug delivery efficiency by allowing it to be easily detached from the top of a disposable drug delivery patch. There is this.

상기와 같은 목적을 달성하기 위한 본 발명에 따른 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치는, 전기에너지를 공급하는 전지와 전지 하우징이 포함된 전지부와; 상기 전지부의 전지의 양(+)극과 음(-)극에 각각 전기적으로 연결되는 제 1전기전도층과 제 2전기전도층을 포함하는 전극부와; 일회용 약물 전달 패치의 상부에 쉽게 탈부착될 수 있는 연결부;를 포함하여 구성된다.Disposable drug delivery patch detachable iontophoresis device according to the present invention for achieving the above object includes: a battery unit including a battery for supplying electric energy and a battery housing; An electrode part including a first conductive layer and a second conductive layer electrically connected to a positive (+) electrode and a negative (-) electrode of the battery of the battery part, respectively; It is configured to include; a connection that can be easily detached from the top of the disposable drug delivery patch.

이와 같은 본 발명에 따른 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치는, 전지부와 일회용 약물 전달 패치의 상부에 쉽게 부착할 수 있게 함으로써, 전지부가 일회용 약물 전달 패치에 고정되어 있기 때문에, 활성물질, 약물을 피부에 직접 도포함으로서 생기는 끈적함, 이물감을 해소하면서 동시에 새로운 장치를 고안하지 않고, 기존의 일회용 약물 전달 패치에 고정화된 담체를 활용하여 약물 전달 효율을 향상시킬 수 있는 효과를 제공한다.Such a disposable drug delivery patch detachable iontophoresis device according to the present invention allows the battery part and the disposable drug delivery patch to be easily attached to the upper part, so that the battery part is fixed to the disposable drug delivery patch. , It provides the effect of improving drug delivery efficiency by using a carrier immobilized on an existing disposable drug delivery patch without devising a new device while solving the stickiness and foreign body sensation caused by direct application of the drug to the skin.

도 1은 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치의 구성을 도시한 사시도.
도 2는 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치의 구성중 일회용 약물 전달 패치가 연결부에 결합된 상태를 나타낸 도면.
도 3은 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치의 사용 상태를 나타낸 도면1 is a perspective view showing the configuration of a disposable drug delivery patch detachable iontophoresis device according to the present invention.
2 is a view showing a state in which a disposable drug delivery patch is coupled to a connection part of the configuration of a disposable drug delivery patch detachable iontophoresis device according to the present invention.
3 is a view showing a state of use of a disposable drug delivery patch detachable iontophoresis device according to the present invention

이하, 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치의 바람직한 실시예를 첨부된 도면을 참조하여 상세히 설명한다.Hereinafter, preferred embodiments of the detachable iontophoresis device of the disposable drug delivery patch according to the present invention will be described in detail with reference to the accompanying drawings.

도 1은 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치를 도시한 사시도이고, 도 2는 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치의 구성중 일회용 약물 전달 패치가 연결부에 결합된 상태를 나타낸 도면이다.Figure 1 is a perspective view showing a disposable drug delivery patch detachable iontophoresis device according to the present invention, Figure 2 is a disposable drug delivery patch in the configuration of the disposable drug delivery patch detachable iontophoresis device according to the present invention It is a view showing a state coupled to the connection part.

본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치는 전기에너지를 공급하는 전지(1)와 전지 하우징(2)이 포함된 전지부(3)를 포함하는 본체부(4)와 상기 전지부의 전지의 양(+)극과 음(-)극에 각각 전기적으로 연결되는 제 1전기전도층(5)과 제 2전기전도층(6)을 포함하는 전극부(7)와 일회용 약물 전달 패치의 상부에 쉽게 탈부착될 수 있는 연결부(8)를 포함하여 구성된다.Disposable drug delivery patch detachable iontophoresis device according to the present invention includes a main body part 4 including a battery part 3 including a battery 1 for supplying electric energy and a battery housing 2 The electrode unit 7 including the first electroconductive layer 5 and the second electroconductive layer 6 electrically connected to the positive (+) and negative (-) electrodes of the branch's battery, and disposable drug delivery It consists of a connection part 8 that can be easily detached from the top of the patch.

상기 연결부(8)는 전극부(7)와 연결되어 있는 둥근 원기둥 형상의 연결핀(9)과 하부는 둥글고 상부는 뾰족한 고정 고리부(10)로 구성된다.The connection part 8 is composed of a circular cylindrical connection pin 9 connected to the electrode part 7 and a fixed ring part 10 having a rounded lower part and a pointed upper part.

상기 연결핀(9)은 전극부(7)의 제 1전기전도층(5)과 제 2전기전도층(6)에 각각 연결되어 일회용 약물 전달 패치의 담체(11)에 상기 전지부(3)에서 발생한 전기 에너지를 전달한다. 이 과정에서 고정 고리부(10)는 연결핀(9)과 일회용 약물 전달 패치의 약물이 포함된 담체(11) 사이의 결합을 단단히 고정시켜 쉽게 해체되지 않도록 보조한다.The connection pins 9 are connected to the first conductive layer 5 and the second conductive layer 6 of the electrode part 7, respectively, so that the battery part 3 is attached to the carrier 11 of the disposable drug delivery patch. It transmits the electric energy generated in In this process, the fixing ring portion 10 securely fixes the bond between the connection pin 9 and the drug-containing carrier 11 of the disposable drug delivery patch to assist in preventing easy disassembly.

상기와 같이 구성된 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치의 사용 방법을 첨부된 도면을 사용하여 설명하면 다음과 같다.A method of using a disposable drug delivery patch detachable iontophoresis device according to the present invention configured as described above will be described with reference to the accompanying drawings.

도 3는 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치의 사용 상태를 나타낸 도면으로 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치가 부착된 일회용 약물 전달패치가 사용자의 신체에 접착되어 사용되는 상태를 나타낸 사시도이다.Figure 3 is a view showing the use of the disposable drug delivery patch detachable iontophoresis device according to the present invention, a disposable drug delivery patch attached to the disposable drug delivery patch detachable iontophoresis device is adhered to the user's body It is a perspective view showing the state in use.

먼저, 본 발명에 의한 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치를 사용하기 위해서는 도시하지는 않았지만, 피부에 일회용 약물 전달 패치를 부착하고, 도 4a에서처럼, 사용자가 본체부(3) 측면을 잡고 연결부(8)를 일회용 약물 전달 패치의 상부로 이동해 아래로 눌러 일회용 약물 전달 패치의 담체(11)에 부착시킨다. 이와 같은 상태가 되면, 고정 고리부(10)의 뾰족한 상부가 일회용 약물 전달 패치의 상부의 중간 지점에 걸리게 되면서 결합을 단단히 고정시킨다. First, in order to use the disposable drug delivery patch detachable iontophoresis device according to the present invention, although not shown, a disposable drug delivery patch is attached to the skin, and as shown in FIG. 4A, the user holds the side of the main body 3 and the connection part (8) is moved to the top of the disposable drug delivery patch and pressed down to attach it to the carrier 11 of the disposable drug delivery patch. In this state, the pointed upper portion of the fixing ring portion 10 is caught in the middle point of the upper portion of the disposable drug delivery patch, and the coupling is firmly fixed.

사용자는 이후 본체부(3)를 조작하여 작동을 시작하게 되면, 전지부(3)의 전지(1)에서 전기 에너지가 제 1전기전도층(5)과 제 2전기전도층(6)을 포함하는 전극부(7)에 전기에너지를 전달하게 되고, 전극부(7)와 연결된 연결부(8)의 연결핀(9)을 통해 전기 에너지가 이동하게 된다. 상기 연결핀(9)은 일회용 약물 전달 패치의 담체(11)에 부착된 상태로, 전기에너지에 의해 담체(11)에 포함된 약물의 전달을 향상시키게 된다. When the user starts the operation by manipulating the main body 3 afterwards, the electric energy in the battery 1 of the battery part 3 includes the first conductive layer 5 and the second conductive layer 6 Electrical energy is transmitted to the electrode part 7 and the electrical energy is transferred through the connection pin 9 of the connection part 8 connected to the electrode part 7. The connection pin 9 is attached to the carrier 11 of the disposable drug delivery patch and improves delivery of the drug contained in the carrier 11 by electric energy.

1 : 전지 2 : 전지하우징
3 : 전지부 4 : 본체부
5 : 제 1전기전도층 6 : 제 2전기전도층
7 : 전극부 8 : 연결부
9 : 연결핀 10 : 고정 고리부
11 : 약물이 포함된 담체1: battery 2: battery housing
3: battery part 4: main body part
5: first electrically conductive layer 6: second electrically conductive layer
7: electrode part 8: connection part
9: connection pin 10: fixing ring portion
11: carrier containing drug

Claims (4)

전기에너지를 공급하는 전지부와;
상기 전지부의 전지의 양(+)극과 음(-)극에 각각 전기적으로 연결되는 제 1전기전도층과 제 2전기전도층을 포함하는 전극부와;
일회용 약물 전달 패치의 상부에 탈부착될 수 있는 연결부;를 포함하여 구성되는 것을 특징으로 하는 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치.
 All branches to supply electric energy and;
An electrode unit including a first conductive layer and a second conductive layer electrically connected to a positive (+) electrode and a negative (-) electrode of the battery of the battery unit , respectively;
Disposable drug delivery patch detachable iontophoresis device, characterized in that it comprises a; connection portion that can be attached to the top of the disposable drug delivery patch.
 제 1 항에 있어서, 상기 연결부는 전극부와; 연결되어 있는 다양한 형상의 연결핀과; 연결부와 일회용 약물 전달 패치와의 결합을 단단하게 고정할 수 있는 고정 고리부로; 구성되는 것을 특징으로 하는 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치.
The method of claim 1, wherein the connection part comprises an electrode part; Connection pins of various shapes connected ; With a fixing ring that can securely fix the connection between the connection part and the disposable drug delivery patch; Disposable drug delivery patch detachable iontophoresis device, characterized in that configured.
 제 2 항에 있어서, 상기 연결부의 고정 고리부를 제외한 일회용 약물 전달 패치의 담체 등 소정 위치에 약물 전달 효율을 증가시키도록 전극부의 양(+)극과 음(-)극 사용자의 신체 사이에 전기적 회로가 형성되는 것을 특징으로 하는 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치.
2 wherein, to a support of a disposable drug delivery patch except the fixing ring, and the like to increase the drug delivery efficiency in a predetermined position the electrode portion the amount of the connection (+) polarity and negative (-) electrically between the electrode user's body circuit Disposable drug delivery patch detachable iontophoresis device, characterized in that formed.
 제 3 항에 있어서, 상기 일회용 약물 전달 패치는 전기에너지가 이동하여 회로를 형성할 수 있으며, 약물을 포함하고 있는 담체와 사용자의 신체에 부착될 수 있는 접착제가 포함된 접착 패치로 형성되어 있는 것을 특징으로 하는 일회용 약물 전달 패치 탈부착형 이온토포레시스 장치.
The method of claim 3, wherein the disposable drug delivery patch is formed of an adhesive patch including a carrier containing a drug and an adhesive that can be attached to the user's body, and the electrical energy can move to form a circuit. Disposable drug delivery patch detachable iontophoresis device, characterized in that.
KR1020190082360A 2019-07-09 2019-07-09 Disposable drug delivery patch detachable iontophoresis device KR20210006574A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100610252B1 (en) 2004-07-01 2006-08-10 주식회사 엘지생활건강 Iontophoresis device
KR100730582B1 (en) 2006-11-20 2007-06-20 아람휴비스(주) An apparatus for iontophoresis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100610252B1 (en) 2004-07-01 2006-08-10 주식회사 엘지생활건강 Iontophoresis device
KR100730582B1 (en) 2006-11-20 2007-06-20 아람휴비스(주) An apparatus for iontophoresis

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