KR20210006073A - Non-invasive type core body temperature thermometer for smart monitoring - Google Patents

Abstract

The present invention relates to a smart noninvasive thermometer for monitoring a core temperature which applies and calculates a heart rate sensor to increase the prediction accuracy of a core temperature and the structure of a skin temperature sensor for minimizing the influence on external surroundings, integrates all sensors including an ambient temperature sensor, a signal processing unit, a communication unit, and a power supply unit all in a single device, and calculates the core temperature through a temperature estimation correction coefficient calculated by a multivariable regression analysis method and a heart rate or a boost trap method and a skin temperature and an ambient temperature measured by respective sensors to predict the core temperature. The smart noninvasive thermometer for monitoring a core temperature comprises: a case (10) having an empty space for embedding a prescribed electronic component therein; a circuit board (40) having components including a PMIC (34) for managing power, a CPU (36), and a plurality of electronic temperature sensors of various functions mounted thereon in the case (10); a battery (42) to supply power; an insulation pad (44) to block thermal and electrical interference between various components and the sensors; and a flexible board (50) flexibly connecting the sensors and the CPU (36).

Description

Non-invasive type core body temperature thermometer for smart monitoring}

The present invention relates to a non-invasive smart thermometer for monitoring core body temperature, and more specifically, a structure of a skin temperature sensor for minimizing influence on the external surroundings, and a ratio that can increase the accuracy of prediction of core body temperature and monitor externally in real time. It relates to an invasive smart thermometer.

In general, in the body of a constant-temperature animal, nutrients such as proteins and carbohydrates and fats are constantly burned through oxidation to generate heat, and an almost constant body temperature is maintained by heat dissipation outside the body and the body temperature control action. Because the breakdown of homeostasis leads to disease or death, it is very important to maintain the homeostasis of the body environment, including body temperature, pH, osmotic pressure, and each biochemical component, in order to maintain life.

It is very important to discover vital signs, that is, changes in the subject's health status, through measurements of the subject's body temperature, respiration, pulse, and blood pressure in a wide range of situations. From this point of view, measurements have been made on the core body temperature of the human body. In general, the core body temperature is around 37℃, the average of 34~35℃ on the skin surface, and there is a case where it is considerably lower than the environmental temperature at the peripheral part of the limb. Normally, the body temperature of healthy adults is around 36.5℃ in axillary gum temperature (measurement of armpit body temperature), but the elderly are slightly lower than this, and infants are slightly higher. The core body temperature (rectal standard: 37.0 ±0.5℃) is at least 2℃ higher than the skin body temperature, and proper core body temperature maintenance is closely related to the immune function, and the decrease in core body temperature is the cause of various diseases.

Most of the core body temperature is measured in the eardrum, axilla, rectum, and oral cavity, depending on the position of the body, and this is a very passive measurement method using a vitreous thermometer, electronic thermometer, or tympanic thermometer. It has the disadvantage that continuous monitoring is difficult. In addition, most of the recent smart thermometers have a large measurement error because they predict the core body temperature compensated for the skin temperature.

1 is a graph showing a change in skin heat conduction through expansion and contraction of blood vessels according to a change in ambient temperature, and FIG. 2 is a graph showing a change in body temperature according to an increase in ambient temperature. When the ambient temperature drops, the body constricts blood vessels to suppress heat generation to preserve heat, and when the ambient temperature rises, the body expands blood vessels to increase heat transfer to emit heat. There is little change in body temperature in the surrounding environment temperature range of 20℃ to 60℃.

3 is an illustration diagram showing body temperature according to ambient temperature, where A is a body temperature for each body part in a cold ambient temperature state, B is a body temperature for each body part in a warm ambient temperature state, and C is a body temperature for each facial part. Referring to FIG. 3, the body preserves heat in order to maintain a core body temperature of 37° C. in the cold environment of A, and the skin is expanded. In the warm environment of B, the body volume maintained at 37℃ expands. On the face of C, the forehead area is the highest and the cheek area is the lowest. The yellow areas in A, B, and C are the distal regions of the body that help regulate body temperature by constricting blood vessels when body temperature drops.

Next, several prior art related to the present invention will be described. Republic of Korea Patent Publication No. 10-2019-0010637 (published on January 30, 2019) discloses a'portable menstrual monitor configured to measure the eardrum temperature'. This is a wearable device that can measure a user's core body temperature and other vital signs in various situations. By providing an infrared thermopile at the innermost end of the ear insert, it is a technology that ensures that the infrared thermopile is provided as close as possible to the eardrum that will be used to provide an indication of deep body temperature.

This earpiece thermometer is excellent in terms of convenience and accuracy of wearing for people who exercise, but if it is necessary to monitor biometric information for a long time, the battery use time is short because the battery use time is only 4 to 5 hours with the latest technology. Care and obesity prevention In adult care, it is unsuitable as a bio-signal measuring device that is required for a long time, and when considering the size of the product, the ear insertion mounting method has a disadvantage that it is very inconvenient for daily life activities compared to the wearing or attachment type. In addition, this patent has a problem in that the eardrum temperature is close to the core body temperature, but the accuracy is deteriorated due to the influence of the external temperature if it is not accurately mounted on the ear.

Korean Patent Registration No. 10-1506075 (registered on March 19, 2015) provides a “non-invasive and non-constrained tomometer for monitoring deep body temperature”. This is a thermometer with a structure that calculates and measures the body temperature of the core through the skin temperature and air temperature measured by a number of thermistors and a temperature estimation correction factor with a thermal conductive material on the skin with the case. Cotton, that is, air in the chest allows non-invasive monitoring of body temperature in the core. In particular, since the measurement site is in the chest, it is possible to perform non-constrained measurements, which is more efficient than the conventional manual measurement method and has the effect of enabling long-term deep body temperature monitoring.

However, the present invention is superior to the one measured and complemented by measuring the single layer body temperature, i.e., the core body temperature prediction through the skin temperature measurement data in several places and the heat conduction characteristics of the skin. Accuracy is degraded because it does not refer to the heat dissipation characteristic by.

In addition, Korean Patent Registration No. 10-1569140 (registered on November 09, 2015) provides a'wireless thermometer', which measures the temperature by attaching it to a part of the body of the subject, and stores the measured temperature information by RFID or The body temperature information of the subject can be collected by transmitting it to an external device such as an RFID reader or smart phone through NFC communication, etc., and by utilizing the RF pass method, the measuring instrument generates electromagnetic waves (RF signals) regardless of whether the measuring instrument's driving power is applied. It is a wireless thermometer that is harmless to the human body of a child or the elderly with weak immunity due to the absence of ). Therefore, the stored data is not transmitted continuously, but only once, thereby minimizing power consumption, enabling stable driving with only power transmitted from an external device in an environment where power is not supplied by itself, and the ECG information of the subject is stored. Accompanying the transmission to an external device, the transmission of various information is selectively transmitted in serial or parallel, and has the advantage of being able to select the specification of fast transmission or low power transmission according to the user's choice, but simply It is attached to a part to measure the temperature, and the measured temperature information is simply transmitted to another mobile communication device using the RF wireless method.It is how to measure body temperature and how to correct the measured body temperature value differently from the core body temperature. I am concerned about the unfinished invention that has not been addressed.

In Korean Patent Registration No. 10-1420200 (registered on July 10, 2014), a thermal imaging camera can detect the actual body temperature and the body temperature that minimizes the error range, so when applied to the patient in the room, the body temperature of the patient can be accurately detected. It provides a'body temperature detection system using a thermal imaging camera' that can create conditions for performing follow-up medical treatments, but this is a non-invasive, non-contact method, so it has hygienic and convenient advantages, There is still a disadvantage that there are many errors because it requires correction and the body temperature is corrected for skin temperature.

An object of the present invention is to provide a non-invasive core temperature smart monitoring thermometer that solves the disadvantages of the conventional core temperature measuring thermometers. The purpose of this study is to provide a thermometer that does not cause discomfort in daily activities, a thermometer that does not degrade measurement accuracy, and a thermometer that has a minute error in correcting skin temperature after measurement.

In order to achieve the object as described above, the non-invasive deep body temperature smart monitoring thermometer of the present invention,

A case having an internal space in which a predetermined electronic component is embedded, a battery configured in the internal space of the case to supply power, and a skin temperature configured on the lower surface of the case to contact the human body to measure skin temperature A circuit board on which a sensor and a pulse sensor for measuring the pulse, a CPU configured in the inner space of the case and receiving and analyzing the skin temperature or pulse measured from the skin temperature sensor or the pulse sensor, and a PMIC for managing the battery are mounted And, an insulation pad configured between the circuit board and the skin temperature sensor or pulse sensor to block thermal and electrical interference, and a flexible substrate flexibly connecting the skin temperature sensor or pulse sensor and the CPU.

In addition to this configuration, the case is made by assembling an upper case and a lower case to each other, and includes an ambient temperature sensor that is spaced apart from the CPU on the circuit board to measure an ambient temperature, and the skin temperature sensor or the pulse sensor It is preferable that the case is disposed on the lower surface of the case toward the skin surface.

In the electronic temperature sensor, it is preferable to arrange a heat shielding pad on the upper surface of a heat conductive material of a heat conductive hollow metal tank type in order to block heat transfer from the case.

The heat conductive material is any one selected from silver, copper, gold, aluminum, tungsten, brass, and nickel as the material, and the heat conductive adhesive is any one selected from epoxy, silicone, and polyurethane series, and the heat shielding pad, It is preferable to use any one selected from plastic pads such as FRP and ABS, foam rubber pads, silicone, and ceramic-based paints. The ambient temperature sensor is preferably arranged in isolation at a predetermined distance from the CPU or PMIC on the circuit board, and the pulse sensor for measuring heart rate is arranged in parallel with the skin temperature sensor on the lower surface of the case, and It is a configuration that includes an LED and a photoresist, and it is preferable to use a reflective or transmissive type for measurement of blood flow fluctuations in blood vessels, and the pulse sensor is preferably an IR diode when measuring blood oxygen saturation (sPo ₂ ), , In order to display the measured core body temperature or heart rate'within the normal range, above/below the range', it is recommended that a three-color LED is further installed while electrically connected to the circuit board.

The thermometer may further include a strap connected to the case to be worn on the chest, head, wrist, upper arm, etc., so that the thermometer can be attached to the skin without limitation to a specific location to be measured, such as around the shoulder blades and clavicles. It is preferable to further install an adhesive on the lower case, and it is preferable to further include a communication module (BLE) that transmits the result calculated from the CPU to the outside on the circuit board.

Therefore, in order to exclude the ambient influence of the temperature sensor in contact with the skin surface when measuring the core temperature, and to minimize the temperature error due to the external environment and the heating part of the temperature sensor, the structure of the skin temperature sensor is composed of an electronic temperature sensor and a sensor fixation and measurement signal. It is composed of a thin film flexible substrate for transfer and a tank containing the substrate.To efficiently transfer skin heat to the sensor, the material of the tank containing the temperature sensor is made of a metal material with excellent heat transfer characteristics, and the substrate on which the sensor is mounted is used. As the material for fixing to the tank, thermal epoxy or adhesive tape with excellent temperature transfer coefficient is used, and the circuit board and battery including the CPU and power management IC (PMIC) are used. In order to block heat from being transferred to the skin temperature sensor in the vertical lower part, a pad made of a material with high heat resistance (eg, polystyrene), adhesive tape, paint is used to protect the skin temperature sensor from heat and fix the sensor. The lower case is also made of a material with high heat resistance to prevent heat from the thermometer from being transferred directly to the skin.

The non-invasive deep body temperature smart monitoring thermometer of the present invention has the following effects.

1. It is worn on the wrist or upper arm, or on the skin of the human body, such as the temporal artery, chest or scapula, and around the clavicle, so that the surrounding environment and the temperature are insulated so that automatic measurement is possible.

2. In addition to measuring core temperature, it is possible to measure pulse rate, respiration rate, and blood oxygen saturation (sPo ₂ ) through these correlations. Therefore, in case of an emergency, you can quickly contact the emergency center or the nearest hospital.

3. Continuous remote body temperature monitoring is possible using a smartphone or PC.

4. For the elderly or non-urgent home patients in need of health care, it is possible to continuously remotely monitor related data through a smartphone or PC through wireless communication such as Bluetooth or WIFI. This eliminates the need to wait for a caregiver or guardian for 24 hours, and can quickly contact an emergency center, hospital, or guardian in an emergency.

1 is a graph showing the variation of skin heat conduction through expansion and contraction of blood vessels according to changes in ambient temperature,
2 is a graph showing a change in body temperature according to an increase in ambient temperature,
3 is an illustrative diagram showing body temperature according to ambient temperature, where A is a body temperature for each body part in a cold ambient temperature state, B is a body temperature for each body part in a warm ambient temperature state, and C is a body temperature for each facial part.
Figure 4 is an explanatory diagram showing the structure of the non-invasive deep thermometer of the present invention,
5 is a cross-sectional view illustrating a sensor structure as a component constituting the non-invasive deep thermometer of the present invention;
6 is a block diagram showing the operating principle of the thermometer of the present invention;
Figure 7 is an explanatory diagram showing a use state of the thermometer of the present invention.

Hereinafter, with reference to the accompanying drawings will be described in detail with respect to the non-invasive deep body temperature smart monitoring thermometer of the present invention. The present invention is not limited to the embodiments disclosed below, but may be implemented in a variety of different forms, only the present embodiment is intended to complete the disclosure of the present invention, and the scope of the invention to those of ordinary skill in the art. It is provided to inform you.

4 is an explanatory view schematically showing the overall structure of the non-invasive core thermometer of the present invention, and FIG. 5 is a cross-sectional view illustrating a sensor structure as a component of the non-invasive core thermometer of the present invention. As shown in FIGS. 4 and 5, the non-invasive thermometer according to the present invention is basically worn in an appropriate position using a strap or attached to an appropriate skin using an adhesive tape. .

Reference numeral 10 denotes a case for protecting various internal parts, and the case 10 is preferably assembled in a form in which two upper case 12 and lower case 14 are joined. In the case (10) I, a plurality of thermally conductive materials such as a hollow metal tank-type heat conductive material 22 and a heat conductive adhesive 24, a heat shielding pad 26 as a heat shielding material, and a plurality of electronic temperature sensors ( Alternatively, the thermistor: Ts; Tc) (30a), (30b), a pulse sensor (PPG: Pt: light emitting unit, Pr: receiving unit) 32, and a circuit board 40. Reference numeral 34 denotes a Power Management Inregrated Circuit (PMIC) that manages power, 36 a CPU, 42 a battery, 44 an insulating pad, 50 a flexible substrate, and 52 a human skin.

5 shows the detailed configuration of the thermometer of the present invention in more detail. The case 10 uses a heat-blocking material to protect the skin and the skin temperature sensor Ts from the heat of the thermometer. On the lower surface of the case 10, a skin temperature sensor 30a, an ambient temperature sensor 30b, and a pulse sensor (PPG) 32 are disposed toward the skin surface. The metal tank of the skin temperature sensor 30a has a circular or square cylindrical shape, but can be applied in other shapes. The thermally conductive material 22 and the thermally conductive adhesive 24 are made of a material having high thermal conductivity. The upper part of the thermal conductive material 22 uses a heat shielding pad 26 to block heat from the thermometer from being transferred downward.

In more detail, the plurality of sensors (Ts) (PPG) (Tc) are installed on the lower surface of the case 10 composed of the heat conductive material 22 and the heat conductive adhesive 24 to contact the skin A skin temperature sensor 30a, which is a first temperature sensor Ts, which measures temperature and heart rate, a pulse sensor 32, which is a blood flow sensor (PPG), is installed on one side of the circuit board 40 in the case 10. It consists of an ambient temperature sensor 30b that is a second temperature sensor Tc that measures the ambient temperature passing through the upper case 12.

The heat conductive material (metal tank) 22 is made of any one metal material selected from silver, copper, gold, aluminum, tungsten, brass, nickel, etc., and the heat conductive adhesive 24 for fixing the board or various sensors is used for impact , The train to block heat from the upper portion of the circuit board 40 and battery 42 to the skin temperature sensor 30a, etc., using an epoxy, silicone, polyurethane series excellent in vibration and environmental characteristics However, as the pad 26, it is preferable to use plastic pads such as FRP and ABS, foam rubber pads, silicone, and ceramic-based paints.

The ambient temperature sensor 30b is located on a circuit board in a location isolated from the CPU 36 or PMIC 34, and is a metal tank with excellent thermal conductivity mounted on the case 10 to react sensitively to the ambient temperature. It is in close contact with the type of heat conductive material 22, and a thermal adhesive 24 is used for effective heat transfer.

The pulse sensor 32 for measuring heart rate may be mounted on the lower surface of the case 10 in parallel with the skin temperature sensor 30a. The pulse sensor 32 is composed of a green LED (or red) as a light-emitting diode and a photoresist as a light-receiving diode, and can measure fluctuations in blood flow in blood vessels in a reflective or transmission method. When the heart expands and contracts repeatedly, blood volume increases and decreases repeatedly in the peripheral blood vessels. By measuring this repetition cycle, the heart rate per minute can be measured. By adding an IR diode to the pulse sensor 32, blood oxygen saturation (sPo ₂ ) can also be measured.

6 is a block diagram showing the operating principle of the thermometer of the present invention. A predetermined measurement value is obtained from the skin temperature sensor 30a composed of each thermistor Ts (Tc) and the ambient temperature sensor 30b or the pulse sensor 32 which is a heart rate sensor (PPG/sPo2). A biometric (biometric) sensor hub 60 receives signals of temperature or heart rate measured by each of the sensors, and processes analog or digital signals such as signal amplification and noise signal filtering. The system control unit (MCU) 70 that controls the whole thermometer removes non-periodic noise that is difficult to process in hardware, and corrects the measured skin body temperature and ambient temperature information first by the bootstrap method and multivariate regression analysis method It is calculated by software through a deep temperature prediction program made using the skin body temperature, ambient temperature and heart rate information, and the correction factor calculated by the bootstrap method and multivariate regression analysis method.

The vital signs information calculated as described above can be connected to the smartphone 100 of the person or guardian through the communication module (BLE) 72 located on the circuit board 40 and displayed on the screen. This interfacing means Bluetooth, Wi-Fi, etc., but not particularly limited. Therefore, continuous remote monitoring is possible through a smartphone or PC, which does not require waiting for a caregiver or guardian for 24 hours, and it is possible to contact an emergency center, hospital, or guardian in an emergency. That is, the skin temperature and heart rate information measured by the sensor is transmitted to the circuit board while the lower part of the case 10 is placed on the skin, and the signal from the ambient temperature sensor is transmitted from the circuit board to the bootstrap method and the multivariate regression method. The body temperature of the core is calculated and measured together with the calculated temperature estimation correction coefficient, and vital sign information such as core body temperature is transmitted to the smartphone or PC of the person concerned such as the person or caregiver through wireless communication such as Bluetooth or WIFI for continuous monitoring. It is possible.

Ambient temperature sensor related to temperature measurement in clothes or in an exposed space is mounted by making a heat isolation island as far as possible from the heating part of the circuit board 40 and as close as possible to the upper case 12. Therefore, the external temperature must be easily measured, and thermal epoxy or thermally conductive pads, tapes, etc. are used for each temperature sensor and case 10. The skin temperature sensor 30a and the pulse sensor 32 attached to the lower case 14 and electrically connected to the circuit board 40, and the ambient temperature sensor 30b mounted on the upper part of the circuit board 40 are analog It is connected to the signal processing device and the CPU 36.

In addition, while being electrically connected to the circuit board 40, it is installed on the upper surface of the case 10 to display the measured heart body temperature or heart rate within the normal range or above/below the range (green, yellow, It is preferable to further include red).

In addition, in order to wear the non-invasive thermometer of the present invention to the chest, head, wrist, upper arm, etc., a strap (not shown) installed by connecting to the case 10, and around the shoulder blade and clavicle, etc. It is preferable to further include an adhesive installed on the lower case 14 so that it can be attached to the skin.

7 is an explanatory diagram showing a use state of the thermometer of the present invention. This drawing shows the process of calculating and measuring the body temperature of the core through the two thermistors (Ts) (Tc) or heart rate sensors (PPG/sPo2) and the circuit board 40 constituting the non-invasive thermometer of the present invention. will be. The non-invasive thermometer is mounted on the deep (rectum, heart, eardrum, oral cavity, etc.) or the skin layer above the artery connected to the core as shown in FIG. 7, and the Tcore represents the temperature of the deep artery, and the skin temperature minimized from the outside Ts is the temperature measured by the thermistor Ts as described above, Tc is the temperature of the local area in the clothes when the thermometer is inside the clothes, as shown in FIG. 7, and the thermometer shows the temperature of the area where there is no clothes, that is, the wrist, forehead, etc. When attached, it indicates the outside air temperature. Although the Ts and Tc represent the measured temperature as described above, they also mean each thermistor. In FIG. 7, reference numeral 62 denotes a micro clothing ambient.

Heat is transferred between the body and the surrounding environment by convection, evaporation, and radiation. According to Fourier's law of heat conduction, the amount of heat conduction is proportional to the temperature gradient, which is expressed by the following equation.

(Reference formula)

Where fh is the amount of heat flowing through the unit area per unit time (heat flux), λ is the thermal conductivity, T is the temperature, and x is the distance.

The heat loss (q in W) at the interface is proportional to the difference between the skin temperature (Ts in °C) and the ambient temperature (Tc °C), and assuming that the heat flows only in the vertical direction and the thermal conditions of the measurement area are constant, as follows: Can be expressed.

Equation (1)

Where h is the heat transfer coefficient (W / (m²·℃)) and A is the heat exchange surface area in the skin (m²). The heat flux from arterial blood to the skin is related to the temperature difference between the core (Tcore in °C) and the skin (TSkin in °C).

Equation (2)

Where w is the blood mass flow rate in kg / s and c is the blood heat capacity in J / (kg·℃). Assuming that heat loss and generation are the same in Equations (1) and (2) above, Equation (3) is given below.

Equation (3)

Dividing both sides of equation (3) by A,

Equation (4)

Where p is the perfusion rate (blood flow per unit area). To summarize Tcore:

Equation (5)

Here, k is generally expressed as a polynomial of skin temperature, but since it is a constant that takes into account heat transfer or loss due to blood flow, it should be included as heart rate information, which is blood flow information, to increase the accuracy of the prediction, and also the measurement location and prediction of the skin temperature. In order to correct the error when the location of the core temperature to be performed is significantly different, consider the core temperature offset value (Tcoreoffset).

Equation (6)

In Equation (6), the heart rate information (Hr) and exercise intensity (Wf) included in the Tcoreoffset are separated and reorganized as follows.

Equation (7)

Here, the correction factors a, b, d, e, and Toffset can be calculated through bootstrap or multivariate regression analysis, and the exercise intensity (Wf) can be found through the carbonet formula% reserve heart rate (HRR (%)). .

Equation (8)

Where Hr is the measured pulse rate, Hr0 is the pulse rate at rest or after 10 minutes rest,

Hax = male: 214-(0.8*age), female: 209-(0.7*age)

Eventually, when purchasing the device, input the gender, age, and resting pulse rate, and if the pulse rate is measured, the exercise intensity (Wf) can be automatically calculated by using curve fitting and polynomial for HRR (%).

The thermometer of the present invention has improved the structure of the skin temperature sensor in order to minimize the temperature error caused by the external environment and the heating part of the temperature sensor when measuring the core temperature. In order to increase the accuracy of core body temperature, a heart rate sensor was applied to calculate the correlation with body temperature. In addition, all of the sensors including the ambient temperature sensor or the signal processing unit, communication unit, and power supply unit are integrated in one device along with these sensors. Accurate body temperature measurement or correlated pulse rate, respiration by calculating the core body temperature using the skin temperature, ambient temperature, heart rate or bootstrap method measured by each sensor and the temperature estimation correction factor calculated based on the multivariate regression method Vital signs such as water or blood oxygen saturation can also be measured. This provides an objective basis to more accurately grasp the health status of the subject.

As a non-invasive thermometer, there is no limit to the measurement location as it can be worn on the chest, head, wrist, upper arm, etc. by attaching a strap to the case, or a temperature sensor can be attached around the coronary artery or chest or shoulder blades and clavicle

In particular, an increase in body temperature can be caused by an increase in blood flow required for human metabolic processes, and the pulse rate increases in the process of releasing heat outside the body by moving blood to the skin surface such as limbs to maintain body temperature homeostasis. Conversely, when the ambient temperature is low and the body temperature is about to decrease, the mechanism acts in the opposite direction and the pulse rate decreases. This means that there is a very close relationship between pulse rate and temperature. Therefore, since it is difficult to predict the core body temperature with little change only with skin temperature and external temperature, which are affected by a lot of external influences, and the error is severe, pulse rate information was confirmed as a necessary factor to compensate for this.

In the present invention, the skin temperature sensor 30a is a metal material having excellent thermal conductivity and is used in a case 10 containing a temperature sensor, and an insulating pad having high thermal resistance ( 44) was used to measure only the skin temperature by blocking the heat generated from the circuit board or battery 42 in the vertical downward direction, and the skin temperature sensor 30a built in the lower case 14 was used to measure only the skin temperature, and the skin temperature sensor 30a It is a type that is fixed by connecting with a thin flexible substrate 50.

In this case, the heart rate sensor required for the prediction of the core body temperature is a complex body temperature homeostasis mechanism, and thus, the prediction of the core body temperature with little change is insufficient only with the skin temperature and the ambient temperature. In consideration of this, in order to reduce the error in prediction, the blood volume in the arterial vessel increases according to the heartbeat by using the pulse sensor 32, an optical reflective sensor (PPG), as an indirect factor that predicts blood flow, which plays an important role in the mechanism of body temperature homeostasis. Or, the heart rate was measured by the degree of decreasing change. Accordingly, the skin temperature sensor 30a and the thin film flexible substrate 50 are connected to the lower case 14 and are located at a predetermined distance apart.

As described above, a non-invasive or non-constrained tomometer for monitoring deep body temperature according to the present invention has been described with reference to the drawings, but the present invention is not limited by the embodiments and drawings disclosed in the present specification. Of course, various modifications may be made by those skilled in the art within the scope of the technical idea of the present invention.

10: case 12: upper case
14: lower case 22: thermal conductive material
24: heat conductive adhesive 26: heat shielding pad
30a: skin temperature sensor 30b: ambient temperature sensor
32: pulse sensor (PPG: Pt: light emitting unit, Pr: receiving unit)
40: circuit board 34: PMIC
36: CPU 42: battery
44: insulation pad 50: flexible substrate
60: biometric sensor hub
70: system control unit (MCU) 72: communication module (BLE)
100: smartphone

Claims (16)

A case 10 having an internal space in which a predetermined electronic component is embedded,
A battery 42 configured in the inner space of the case 10 to supply power,
A skin temperature sensor 30a configured on the lower surface of the case 10 to measure skin temperature in contact with the human body and a pulse sensor 32 for measuring a pulse,
The CPU 36 configured in the inner space of the case 10 and receiving and analyzing the skin temperature and pulse measured from the skin temperature sensor 30a and the pulse sensor 32 and PMIC managing the battery 42 A circuit board 40 on which 34 is mounted,
An insulating pad 44 configured between the circuit board 40 and the skin temperature sensor 30a and the pulse sensor 32 to block thermal and electrical interference,
Non-invasive deep body temperature smart monitoring thermometer, characterized in that consisting of a flexible substrate (50) that flexibly connects the skin temperature sensor (30a) and the pulse sensor (32) and the CPU (36). The non-invasive deep body temperature smart monitoring thermometer according to claim 1, wherein the case (10) is formed by assembling the upper case (12) and the lower case (14). The method according to claim 1, comprising an ambient temperature sensor (30b) for measuring the ambient temperature separated from the CPU (36) on the circuit board (40), the skin temperature sensor (30a) and the pulse sensor (32) Non-invasive deep body temperature smart monitoring thermometer, characterized in that disposed toward the skin surface on the lower surface of the case (10). The flexible method according to claim 3, wherein the feed temperature sensor (30a) is wrapped with a heat conductive material (22) of a heat conductive hollow metal tank, and the skin temperature sensor (30a) is mounted inside the heat conductive material (22). Non-invasive deep body temperature smart monitoring thermometer, characterized in that the substrate 50 is fixed by a thermally conductive adhesive (24). The method according to claim 3 or 4, wherein the electronic temperature sensor arranges a heat shielding pad 26 on the upper surface of the heat conductive material 22 of a heat conductive hollow metal tank type in order to block the heat from being transferred to the case 10 Non-invasive deep body temperature smart monitoring thermometer, characterized in that. The non-invasive deep body temperature smart monitoring thermometer according to claim 4 or 5, wherein the thermal conductive material (22) is any one selected from silver, copper, gold, aluminum, tungsten, brass, and nickel. The method of claim 4, wherein the thermally conductive adhesive (24) is a non-invasive deep body temperature smart monitoring thermometer, characterized in that any one selected from epoxy, silicone, and polyurethane series. The non-invasive deep body temperature smart monitoring thermometer according to claim 4, wherein the heat shielding pad 26 is any one selected from plastic pads such as FRP and ABS, foam rubber pads, silicone, and ceramic-based paints. The non-invasive deep body temperature smart monitoring thermometer according to claim 3, wherein the ambient temperature sensor (30b) is disposed in isolation at a predetermined distance from the CPU (36) or PMIC (34) on the circuit board (40). The non-invasive deep body temperature smart monitoring thermometer according to claim 3, wherein the pulse sensor (32) for measuring heart rate is disposed in parallel with the skin temperature sensor (30a) on the lower surface of the case (10). The non-invasive deep body temperature smart monitoring thermometer according to claim 10, wherein the pulse sensor (32) includes an LED and a photoresist, and the measurement of blood flow fluctuations in blood vessels is one selected from a reflection type or a transmission type. 12. The non-invasive deep body temperature smart monitoring thermometer according to claim 10 or 11, wherein the pulse sensor (32) measures blood oxygen saturation (sPo ₂ ) using an IR diode. The method according to claim 1, wherein the case 10 is electrically connected to the circuit board 40 so that the measured core body temperature and heart rate are displayed as'within the normal range, above/below the range', and a three-color LED is further installed. Non-invasive deep body temperature smart monitoring thermometer, characterized in that. The non-invasive deep body temperature smart monitoring thermometer according to claim 1, wherein the thermometer further comprises a strap connected to the case 10 to be worn on the chest, head, wrist, upper arm, and the like. The method according to claim 1, wherein the thermometer further comprises an adhesive installed on the lower case 14 so that the thermometer can be attached to the skin without limitation to a specific location to be measured, such as around the shoulder blade and clavicle. Non-invasive deep body temperature smart monitoring thermometer. The non-invasive deep body temperature smart monitoring thermometer according to claim 1, further comprising a communication module (BLE) 72 on the circuit board 40 that transmits the result calculated from the CPU to the outside.

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