KR20200115489A - 진단 모델링 방법 및 장치 - Google Patents

진단 모델링 방법 및 장치 Download PDF

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Publication number
KR20200115489A
KR20200115489A KR1020207020232A KR20207020232A KR20200115489A KR 20200115489 A KR20200115489 A KR 20200115489A KR 1020207020232 A KR1020207020232 A KR 1020207020232A KR 20207020232 A KR20207020232 A KR 20207020232A KR 20200115489 A KR20200115489 A KR 20200115489A
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South Korea
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image
reference data
diagnostic model
feature
diagnostic
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Korean (ko)
Inventor
로스 업톤
폴 리슨
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옥스포드 유니버시티 이노베이션 리미티드
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Publication of KR20200115489A publication Critical patent/KR20200115489A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5223—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Clinical applications
    • A61B8/0883—Clinical applications for diagnosis of the heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/488—Diagnostic techniques involving Doppler signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G06T7/0016—Biomedical image inspection using an image reference approach involving temporal comparison
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/46—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
    • A61B8/461—Displaying means of special interest
    • A61B8/463—Displaying means of special interest characterised by displaying multiple images or images and diagnostic data on one display
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10132—Ultrasound image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20081—Training; Learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30048—Heart; Cardiac

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Artificial Intelligence (AREA)
  • Data Mining & Analysis (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Physiology (AREA)
  • Quality & Reliability (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Computation (AREA)
  • Mathematical Physics (AREA)
  • Fuzzy Systems (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Cardiology (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
KR1020207020232A 2017-12-13 2018-12-12 진단 모델링 방법 및 장치 Ceased KR20200115489A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1720791.1A GB2569333A (en) 2017-12-13 2017-12-13 Diagnostic modelling method and apparatus
GB1720791.1 2017-12-13
PCT/EP2018/084642 WO2019115652A1 (en) 2017-12-13 2018-12-12 Diagnostic modelling method and apparatus

Publications (1)

Publication Number Publication Date
KR20200115489A true KR20200115489A (ko) 2020-10-07

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KR1020207020232A Ceased KR20200115489A (ko) 2017-12-13 2018-12-12 진단 모델링 방법 및 장치

Country Status (11)

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US (1) US12002581B2 (https=)
EP (1) EP3724892B1 (https=)
JP (1) JP2021506541A (https=)
KR (1) KR20200115489A (https=)
CN (1) CN111542896B (https=)
AU (1) AU2018382963A1 (https=)
BR (1) BR112020011854A2 (https=)
CA (1) CA3084595A1 (https=)
GB (1) GB2569333A (https=)
SG (1) SG11202005349VA (https=)
WO (1) WO2019115652A1 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024137796A1 (en) * 2022-12-21 2024-06-27 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12245882B2 (en) 2020-01-07 2025-03-11 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12283046B2 (en) 2020-01-07 2025-04-22 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12299885B2 (en) 2022-03-10 2025-05-13 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12324695B2 (en) 2020-01-07 2025-06-10 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12324696B2 (en) 2022-03-10 2025-06-10 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12380560B2 (en) 2022-03-10 2025-08-05 Cleerly, Inc. Systems, methods, and devices for image-based plaque analysis and risk determination
US12440180B2 (en) 2022-03-10 2025-10-14 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2569332B (en) 2017-12-13 2021-06-09 Univ Oxford Innovation Ltd Method and apparatus for analysing images
TWI723312B (zh) * 2018-12-28 2021-04-01 中國醫藥大學附設醫院 電腦輔助直腸癌治療反應預測系統、方法及電腦程式產品
US12042251B2 (en) * 2019-04-24 2024-07-23 BraveHeart Wireless Inc. Systems and methods of arrhythmia detection
JP7730828B2 (ja) * 2020-03-06 2025-08-28 ウルトロミクス・リミテッド ニューラルネットワークを使用した心臓パラメータの評価
US20230098537A1 (en) * 2021-09-24 2023-03-30 International Business Machines Corporation Incremental learning for models with new features
EP4372757A1 (en) 2022-11-21 2024-05-22 Koninklijke Philips N.V. Method and system for processing medical images
EP4442207B1 (en) * 2023-04-07 2025-10-08 Diagnoly Device for guiding a user in ultrasound assessment of an organ

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776063A (en) 1996-09-30 1998-07-07 Molecular Biosystems, Inc. Analysis of ultrasound images in the presence of contrast agent
US6674879B1 (en) 1998-03-30 2004-01-06 Echovision, Inc. Echocardiography workstation
US6447454B1 (en) 2000-12-07 2002-09-10 Koninklijke Philips Electronics N.V. Acquisition, analysis and display of ultrasonic diagnostic cardiac images
US20040077952A1 (en) 2002-10-21 2004-04-22 Rafter Patrick G. System and method for improved diagnostic image displays
US7693563B2 (en) * 2003-01-30 2010-04-06 Chase Medical, LLP Method for image processing and contour assessment of the heart
US7693315B2 (en) 2003-06-25 2010-04-06 Siemens Medical Solutions Usa, Inc. Systems and methods for providing automated regional myocardial assessment for cardiac imaging
US7912528B2 (en) * 2003-06-25 2011-03-22 Siemens Medical Solutions Usa, Inc. Systems and methods for automated diagnosis and decision support for heart related diseases and conditions
EP1522875B1 (en) 2003-09-30 2012-03-21 Esaote S.p.A. A method of tracking position and velocity of object's borders in two or three dimensional digital echographic images
US7951083B2 (en) * 2004-02-05 2011-05-31 Siemens Medical Solutions Usa, Inc. Motion analysis improvements for medical diagnostic ultrasound
JP2005237555A (ja) 2004-02-25 2005-09-08 Jgs:Kk 心臓壁運動の評価方法、心臓壁運動評価装置及びプログラム
US7672491B2 (en) * 2004-03-23 2010-03-02 Siemens Medical Solutions Usa, Inc. Systems and methods providing automated decision support and medical imaging
US20060074315A1 (en) * 2004-10-04 2006-04-06 Jianming Liang Medical diagnostic ultrasound characterization of cardiac motion
US8838215B2 (en) * 2006-03-01 2014-09-16 Angel Medical Systems, Inc. Systems and methods of medical monitoring according to patient state
US8187186B2 (en) 2005-11-08 2012-05-29 Koninklijke Philips Electronics N.V. Ultrasonic diagnosis of myocardial synchronization
DE102006026695A1 (de) 2006-06-08 2007-12-13 Tomtec Imaging Systems Gmbh Verfahren, Vorrichtung und Computerprogrammprodukt zum Auswerten von dynamischen Bildern einer Kavität
US20070299479A1 (en) 2006-06-27 2007-12-27 Ep Medsystems, Inc. Method for Reversing Ventricular Dyssynchrony
US8491794B2 (en) 2007-10-23 2013-07-23 Siemens Industry, Inc. Process for enhanced total organic carbon removal while maintaining optimum membrane filter performance
CN102015076A (zh) 2008-02-19 2011-04-13 Abb研究有限公司 膜分离过程的在线性能管理
JP5491836B2 (ja) 2009-01-30 2014-05-14 株式会社東芝 超音波診断装置、超音波画像処理装置、医用画像診断装置及び医用画像処理装置
JP2011056345A (ja) 2009-09-07 2011-03-24 Toshiba Corp 淡水化システム
US8396268B2 (en) 2010-03-31 2013-03-12 Isis Innovation Limited System and method for image sequence processing
US9734430B2 (en) 2012-01-02 2017-08-15 Mackay Memorial Hospital Evaluation system or determination of cardiovascular function parameters
CA2948046A1 (en) 2014-05-06 2015-11-12 Circle Cardiovascular Imaging Inc. Method and system for analysis of myocardial wall dynamics
US9990587B2 (en) * 2015-01-22 2018-06-05 Preferred Networks, Inc. Machine learning heterogeneous edge device, method, and system
GB201610269D0 (en) 2016-06-13 2016-07-27 Isis Innovation Image-based diagnostic systems
GB2569332B (en) 2017-12-13 2021-06-09 Univ Oxford Innovation Ltd Method and apparatus for analysing images

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12396695B2 (en) 2020-01-07 2025-08-26 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12245882B2 (en) 2020-01-07 2025-03-11 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12283046B2 (en) 2020-01-07 2025-04-22 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12558048B2 (en) 2020-01-07 2026-02-24 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12324695B2 (en) 2020-01-07 2025-06-10 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12555228B2 (en) 2020-01-07 2026-02-17 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12499539B2 (en) 2020-01-07 2025-12-16 Cleerly, Inc. Systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking
US12380560B2 (en) 2022-03-10 2025-08-05 Cleerly, Inc. Systems, methods, and devices for image-based plaque analysis and risk determination
US12406365B2 (en) 2022-03-10 2025-09-02 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12440180B2 (en) 2022-03-10 2025-10-14 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12324696B2 (en) 2022-03-10 2025-06-10 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12299885B2 (en) 2022-03-10 2025-05-13 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
US12599352B2 (en) 2022-03-10 2026-04-14 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination
WO2024137796A1 (en) * 2022-12-21 2024-06-27 Cleerly, Inc. Systems, devices, and methods for non-invasive image-based plaque analysis and risk determination

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BR112020011854A2 (pt) 2020-11-24
SG11202005349VA (en) 2020-07-29
GB201720791D0 (en) 2018-01-24
US12002581B2 (en) 2024-06-04
CN111542896B (zh) 2025-01-03
CA3084595A1 (en) 2019-06-20
GB2569333A (en) 2019-06-19
EP3724892A1 (en) 2020-10-21
WO2019115652A1 (en) 2019-06-20
CN111542896A (zh) 2020-08-14
JP2021506541A (ja) 2021-02-22
AU2018382963A1 (en) 2020-07-30
US20200388391A1 (en) 2020-12-10
EP3724892B1 (en) 2022-01-26

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