KR20200002702A - Brain lesion diagnosis device based on evaluation of visual field defect and evaluation of ocular motility disturbance - Google Patents

Abstract

According to an embodiment of the present invention, a brain lesion diagnosis device based on evaluation of a visual field defect and evaluation of ocular motility disturbance comprises: a display unit providing a marker which needs to be watched by a person to be evaluated during evaluation of a visual field defect and evaluation of ocular motility disturbance; a camera acquiring an eyeball image of the person to be evaluated; a visual field evaluation unit providing a signal for expressing the marker according to a predetermined pattern on the display unit, and evaluating the visual field of the person to be evaluated by receiving and analyzing the eyeball image of the person to be evaluated acquired by the camera while the marker is expressed; an ocular motility disturbance evaluation unit analyzing movement patterns of both eyes by using a reference eyeball picture and a plurality of comparative eyeball pictures of the person to be evaluated which are obtained by the camera, and determining whether the person to be evaluated is defective based on the movement patterns of both eyes; and a diagnosis performing unit determining the location of a lesion according to visual field defect and ocular motility disturbance patterns based on evaluation results from the visual field evaluation unit and the ocular motility disturbance evaluation unit. The present invention can accurately determine various locations of a lesion.

Description

Brain lesion diagnosis device based on evaluation of visual field defect and evaluation of ocular motility disturbance

The present application relates to a device for diagnosing brain lesions based on visual field disorder evaluation and eye movement disorder evaluation results. The present invention relates to an apparatus for diagnosing brain lesions based on visual field disorder evaluation and ocular movement disorder evaluation result capable of accurately determining the location of lesions.

A visual field represents a range of periphery that can be viewed while simultaneously looking at a certain target with one eye, and a pattern in which the field of view is limited according to the position where the lesion is generated is expressed differently. Therefore, visual field examination plays an important role in determining the degree of optic nerve damage in optic neuropathy and in diagnosing, discriminating, and observing the results of central nervous system disease.

Eye movement disorders include the superior rectus, the inferior rectus, the medial rectus, the lateral rectus, the superior oblique, and the inferior oblique, which are responsible for the movement of the eye. 6 muscles of the inferior oblique and junctional and brain lesions of the nerves and muscles 3, 4 and 6 that control these muscles. By moving the eyeballs to various positions and analyzing the disability pattern of the eye movements, it is possible to distinguish the damaged areas among them, and to estimate the etiology based on this.

Since lesions occurring in various areas may affect both visual field and eye movement, analyzing the visual field and eye movement pattern together may diagnose and discriminate the lesion more accurately.

However, until now, a doctor directly evaluates eye movements by visual observation and measures the field of vision by a visual field meter, and then based on the results, the doctor predicts and confirms the location of the lesion. The situation is taking a picture.

As such, in the past, a complex evaluation process is required for the diagnosis of a lesion, and inaccurate prediction may be made according to the doctor's experience and skill level, so that unnecessary brain imaging may be performed. Was limited to be ignored.

An object of the present invention is to evaluate the visual impairment and eye movement disorder evaluation results that can accurately determine the location of various lesions according to the pattern of visual impairment and eye movement disorder based on the evaluation result of the visual disturbance evaluation and eye movement disorder evaluation of the subject To provide a brain lesion diagnosis apparatus based on.

In order to achieve the above object, the brain lesion diagnosis apparatus based on the visual field disorder evaluation and eye movement disorder evaluation results according to an embodiment of the present invention, the marker to be observed by the evaluation target in the visual field disorder evaluation or eye movement disorder evaluation process A display unit provided; A camera for acquiring an eyeball image of the evaluation subject; A visual field evaluation unit for providing a signal for expressing a marker according to a predetermined pattern on the display unit, and evaluating the visual field of the evaluation target by receiving and analyzing an eye image of the evaluation target obtained by the camera while the marker is expressed ; An eye movement disorder evaluation unit for analyzing movement patterns of both eyes using the reference eye photograph and the plurality of comparative eye photographs obtained by the camera, and determining whether there is a disorder of the evaluation subject based on the movement patterns of both eyes; And a diagnosis performing unit configured to determine a location of a lesion according to a pattern of visual field disorder and eye movement disorder based on the evaluation result by the visual field evaluation unit and the eye movement disorder evaluation unit.

According to an embodiment of the present invention, visual disturbance evaluation and eye movement that can accurately determine the location of various lesions according to the pattern of visual impairment and eye movement disorder based on the visual impairment evaluation result and the ocular movement disorder evaluation result of the evaluation subject A device for diagnosing brain lesions based on a result of disability evaluation can be provided.

1 is a block diagram of an apparatus for diagnosing brain lesions based on visual field disorder evaluation and eye movement disorder evaluation results according to an embodiment of the present invention.
2 is a view for explaining a neural network for controlling eye movement and vision.
3 is a diagram illustrating a neural network that controls eye movement when both eyes look to the left.
4 is a view for explaining the pattern of visual disturbances of both eyes that vary depending on the location of the lesion.

The following merely illustrates the principles of the invention. Those skilled in the art, although not explicitly described or illustrated herein, may embody the principles of the present invention and invent various devices that fall within the spirit and scope of the present invention. In addition, all conditional terms and embodiments listed herein are in principle clearly intended to be understood only for the purpose of understanding the concept of the invention and are not to be limited to the specifically listed embodiments and states. do.

In addition, it is to be understood that all detailed descriptions, including the specific embodiments, as well as the principles, aspects, and embodiments of the present invention, are intended to include structural and functional equivalents thereof. In addition, these equivalents should be understood to include not only equivalents now known, but also equivalents to be developed in the future, that is, all devices invented to perform the same function regardless of structure.

Thus, for example, it should be understood that the block diagrams herein represent a conceptual view of example circuitry embodying the principles of the invention. Similarly, all flowcharts, state transitions, pseudocodes, and the like are understood to represent various processes performed by a computer or processor, whether or not the computer or processor is substantially illustrated on a computer readable medium and whether the computer or processor is clearly shown. Should be.

The functionality of the various elements shown in the figures, including functional blocks represented by a processor or similar concept, can be provided by the use of dedicated hardware as well as hardware capable of executing software in association with appropriate software. When provided by a processor, the functionality may be provided by a single dedicated processor, by a single shared processor or by a plurality of individual processors, some of which may be shared.

In addition, the explicit use of terms presented in terms of processor, control, or similar concept should not be interpreted exclusively as a citation to hardware capable of running software, and without limitation, ROM for storing digital signal processor (DSP) hardware, software. (ROM), RAM, and non-volatile memory are to be understood to implicitly include. It may also include hardware for the governor.

In the claims of this specification, components expressed as means for performing the functions described in the detailed description include all types of software including, for example, a combination of circuit elements or firmware / microcode, etc. that perform the functions. It is intended to include all methods of performing a function which are combined with appropriate circuitry for executing the software to perform the function. The invention, as defined by these claims, is equivalent to what is understood from this specification, as any means capable of providing such functionality, as the functionality provided by the various enumerated means are combined, and in any manner required by the claims. It should be understood that.

The above objects, features, and advantages will become more apparent from the following detailed description taken in conjunction with the accompanying drawings, whereby those skilled in the art may easily implement the technical idea of the present invention. There will be. In addition, in describing the present invention, when it is determined that the detailed description of the known technology related to the present invention may unnecessarily obscure the gist of the present invention, the detailed description thereof will be omitted.

1 is a block diagram of an apparatus for diagnosing brain lesions based on visual field disorder evaluation and eye movement disorder evaluation results according to an embodiment of the present invention.

Referring to FIG. 1, the apparatus for diagnosing brain lesions based on visual field disorder evaluation and ocular movement disorder evaluation results according to an embodiment of the present invention includes a display unit 10, a camera 20, a visual field evaluation unit 30, and an eye movement disorder. It may be configured to include an evaluation unit 40 and the diagnostic performing unit 50.

The display unit 10 is to provide a marker that the evaluation target should look at during the visual disturbance evaluation or the ocular movement disorder evaluation process.

According to an embodiment, the display unit 10 may be provided to be spaced apart from both eyes of the subject by a predetermined distance. For example, a head mounted display (HMD), smart glass, smart goggles, and display mounting may be provided. It may be implemented in a form in which both eyes of the subject and the display are spaced apart by a predetermined distance regardless of the movement of the subject to be worn on the head such as a helmet. Accordingly, the evaluating subject can be evaluated in a comfortable posture without having to fix the head for visual impairment evaluation or eye movement impairment evaluation, thereby reducing the discomfort of the subject during the evaluation process. In addition, even if the evaluation subject moves, the display unit 10 moves together with the subject's head, thereby eliminating the need to consider errors caused by the movement.

In addition, the display unit 10 may have a wireless communication function, and through this, the display unit 10 may receive a signal for expressing a marker according to a predetermined pattern from the visual field evaluation unit 30 described later.

The camera 20 is for acquiring an eyeball image of an evaluation target while the evaluation target looks at a marker expressed according to a predetermined pattern through the display unit 10. For example, the camera 20 may be implemented by one or more cameras.

According to an embodiment, the camera 20 may be integrally formed with the display unit 10. In this case, the eyeball image obtained by the camera 20 may be described later by a wireless communication function provided in the display unit 10. The view may be transmitted to the evaluation unit 30.

However, the camera 20 is not limited to being integrally formed with the display unit 10, and each component may be formed separately. In this case, the camera 20 may be provided with a wireless communication function to transmit the obtained eyeball image to the visual field evaluation unit 30.

The visual field evaluation unit 30 provides a signal for expressing a marker according to a predetermined pattern on the display unit 10, and receives and analyzes an eyeball image of an evaluation subject obtained by the camera 20 while the marker is expressed. It is for evaluating the visual field of the evaluation subject.

Here, the predetermined pattern in which the marker is expressed is expressed in the first peripheral position starting from the center of the imaginary circle provided to the display unit 10, and then expressed in the center of the imaginary circle again at the first peripheral position. Again, the expression of the second peripheral position different from the first peripheral position may be repeated.

The eye movement impairment evaluator 40 analyzes the movement patterns of both eyes using the reference eye photograph and the plurality of comparative eye photographs of the subjects obtained by the camera 20, and analyzes the movement patterns of the subjects based on the movement patterns of both eyes. This is to determine the presence of a disability.

Here, the reference eye photograph is an image of the eye when the evaluation subject looks at the front face, and the plurality of comparative eye pictures are the eye when the radiation subject looks at the radial direction according to a predetermined condition for the state in which the evaluation subject looks at the front face. May be taken. To this end, through the display unit 10 can be provided with a marker to observe the direction of the subjects to evaluate the direction of the up, down, left, right, upper left, upper right, lower left and lower, and when the subject is looking at the marker eyeballs Photographs can be taken to capture a plurality of comparative eye pictures

According to one embodiment, the eye movement disorder evaluation unit 40 is based on the position (coordinate value) and the iris shape of the pupils of both eyes when the subject to be examined in each direction in the reference eye photograph and the plurality of comparative eye photographs. The displacement and the convolution angle of the pupil are respectively calculated, and it is possible to determine whether there is an eye movement disorder of the subject based on the displacement of the pupil and / or the torsion angle.

The diagnosis performing unit 50 is for determining the position of the lesion according to the pattern of visual field disorder and eye movement disorder based on the evaluation result by the visual field evaluation unit 30 and the eye movement disorder evaluation unit 40.

Figure 2 is a view for explaining the neural network for controlling the eye movement and vision, Figure 2 (a) shows a neural network for controlling the eye movement, Figure 2 (b) shows a neural network for controlling the vision It is.

Referring to FIG. 2, eye movement is controlled by a neural network in a path corresponding to an up-down species in the coronal cross section of the brain, and the field of view is controlled by a neural network in a transverse path to the eye and the occipital lobe.

3 is a diagram illustrating a control neural network when both eyes see the left side, and an example of the control neural network when both eyes see the left side by activating the lateral rectus on the left side and the medial rectus on the right side. Shows.

Therefore, the combination of two neural networks that control eye movement and visual field can cover most of the brain. Therefore, the analysis of eye movement disorder and visual disturbance pattern can accurately determine the location of lesions (ie, coordinate values).

According to an exemplary embodiment, the diagnosis performing unit 50 may determine abnormal muscles as a result of analyzing the movement patterns of both eyes, and then analyze the patterns of the muscles and associated nerves to determine the positions of various lesions. That is, if the eye movement that does not belong to the predetermined normal range of movement distance or line angle of the pupil is not limited to muscles controlled by a specific cranial nerve, it may be diagnosed that the muscle itself has a lesion. On the other hand, if the eye movement that does not belong to the predetermined normal range is limited to the muscles dominated by a particular cranial nerve it can be determined that there is a lesion in the cranial nerve.

For example, when looking at the front, it is normal, and when looking at the other 7 directions, all of them are normal, but only when looking at the lower left, the vertical coordinate value of the right eye shows a difference from that of the left eye. If it is abnormally small, it can be diagnosed as having a lesion in the right 4th cranial nerve.

In the case of looking at the front, the coordinate point of one pupil is more biased toward the nose, and when looking in the direction of the biased eye, the coordinate movement of the opposite eye appears appropriately, but the coordinate movement of the biased eye is remarkably When limited, lesions can be diagnosed in the cranial nerve 6 of the biased eye.

On the other hand, if only superior oblique muscles in both eyes have movement problems, it can be diagnosed as a brainstem lesion.

In addition, the diagnosis performing unit 50 may further improve the accuracy of the location determination of the lesion in consideration of the visual disturbance pattern.

4 is a view for explaining the pattern of visual disturbances of both eyes depending on the location of the lesion. Referring to FIG. 4, it can be seen that the pattern of visual disturbances of both eyes is expressed according to the location of the lesion in the brain or eye. Accordingly, the diagnosis performing unit 50 may diagnose the location of the lesion in the brain or eye based on whether the visual field disorder pattern belongs to one of the plurality of visual field disorder patterns shown in FIG. 4.

On the other hand, the embodiments of the present invention disclosed in the specification and drawings are merely presented specific examples to easily explain the technical contents and help the understanding of the present invention, and are not intended to limit the scope of the present invention. It will be apparent to those skilled in the art that other modifications based on the technical idea of the present invention can be implemented in addition to the embodiments disclosed herein.

10: display unit
20: camera
30: visual field evaluation part
40: eye movement disorder evaluation unit
50: diagnostic unit

Claims (4)

A display unit for providing a marker to be watched by an evaluator during visual field disorder evaluation or ocular movement disorder evaluation process;
A camera for acquiring an eyeball image of the evaluation subject;
A visual field evaluation unit which provides a signal for expressing a marker according to a predetermined pattern on the display unit, and evaluates the visual field of the evaluation target by receiving and analyzing an eye image of the evaluation target obtained by the camera while the marker is expressed ;
An eye movement disorder evaluation unit for analyzing movement patterns of both eyes using the reference eye photograph and the plurality of comparative eye photographs obtained by the camera, and determining whether there is a disorder of the evaluation subject based on the movement patterns of both eyes; And
Visual field evaluation and eye movement disorder, characterized in that it comprises a diagnosis performing unit for determining the location of the lesion based on the pattern of the visual field disorder and eye movement disorder based on the evaluation result by the visual field evaluation unit and the eye movement disorder evaluation unit Brain lesion diagnosis device based on the evaluation results.
The method of claim 1,
The diagnosis performing unit may determine abnormal muscles based on analysis results of movement patterns of both eyes, and analyze the patterns of muscles and associated nerves to determine the location of lesions. Brain lesion diagnosis device based on.
The method of claim 2,
The diagnosis performing unit is a brain lesion diagnosis device based on the evaluation of visual disturbances and eye movement disorders evaluation, characterized in that if the abnormal muscles are limited to the muscles dominated by a particular brain nerve, the specific brain nerve lesions.
The method of claim 1,
The diagnosis performing unit diagnoses the location of a lesion in the brain or eye based on whether the visual field disorder pattern belongs to a plurality of pre-classified visual disturbance patterns. Lesion diagnosis device.

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