KR20190050187A - Apparatus and method for prevent of posterior capsular opacification - Google Patents

Abstract

Provided is a posterior capsule patterning method that forms a predetermined pattern in the posterior capsule, wherein a first lens is extracted from the eyeball; a shape recognition unit recognizes the three-dimensional shape of the posterior capsule with respect to the space side where a second lens is inserted and the first lens is removed; the recognized 3D shape is transmitted to the control unit; the 3D shape of the posterior capsule is transmitted to a laser irradiation unit from the control unit; and the laser irradiation unit irradiates the laser according to the 3D shape received from the control unit.

Description

BACKGROUND OF THE INVENTION Field of the Invention [0001] The present invention relates to a patterning apparatus and method for preventing posterior capsule opacity,

The present invention relates to a patterning apparatus and method for preventing posterior caps opacity.

Diseases in which the lens in the eye becomes hard or cloudy are being treated in a variety of ways. For example, treatment of cataracts is simple and safe for 15 minutes without anesthesia by removing the opacifying lens and inserting an intraocular lens that can replace the lens's function. According to the 2011 National Health Insurance Corporation, about 308,000 patients underwent cataract surgery. Such cataract surgery is a common and safe procedure, but there is a possibility of a complication called late cataract. This posterior cataractic complication is a common complication that occurs in about 50% of patients with cataract surgery, resulting in cell diffusion into the intraocular lens, resulting in posterior capsular opacity. Currently, laser procedures are performed for posterior cataracts. However, this complication is not only complicated by cataract surgery but also complications such as damage to the intraocular lens, inflammation, elevation of intraocular pressure, and retinal detachment. However, there is no technique to prevent posterior cataract, which is a common complication that causes visual loss after cataract surgery, and it relies on laser treatment with side effects. Therefore, there is a need to develop a technique capable of preventing such posterior cataracts in the first place.

Korean Patent Laid-Open Publication No. 2016-0040807 (Apr. 15, 2016)

One embodiment of the present invention is a method for preventing posterior disease after eye disease treatment by preventing a cell proliferation that causes eye disease by forming a pattern in the posterior capsule before inserting the intraocular lens into the eyeball, And to provide a patterning apparatus and a method therefor.

One embodiment of the present invention relates to a method for preventing posterior capsular opacity, which can prevent secondary disease after eye disease treatment, so as to induce cell proliferation that causes eye diseases in a specific predetermined direction before inserting an intraocular lens into an eyeball And to provide a patterning apparatus and method for performing patterning.

One embodiment of the present invention relates to a patterning apparatus and method for preventing posterior lens opacity for performing a precise laser machining in a postcask by processing a pattern formed on the intraocular lens through a micro-meter or a nano-meter pattern through a laser And to provide the above objects.

The shape recognition unit recognizes the three-dimensional shape with respect to the posterior capsule on the side of the space where the first lens to be inserted with the second lens is removed, transmits the recognized three-dimensional shape to the control unit, Dimensional shape of the posterior capsule is transmitted to the laser irradiation unit and the laser irradiation unit irradiates the laser according to the three-dimensional shape received from the control unit to form a predetermined pattern in the posterior capsule.

The pattern may include one or more irregularities that are processed by a laser and formed independently.

Further, the pattern may include a plurality of concavities and convexities that are processed by a laser and are connected to each other.

Further, the pattern may be formed from the edge of the posterior to the center.

Further, the shape recognizing unit can transmit to the control unit a three-dimensional shape in which three-dimensional distortion including two-dimensional distortion in the XY plane of the posterior capsule and distortion in the Z direction perpendicular to the XY plane is corrected.

The laser irradiation unit may further include: a laser generation unit for generating a laser; A beam expander through which the laser generated from the laser generating portion passes; And a laser focusing unit that receives the laser beam passed through the beam adjusting unit and positions the laser irradiating unit in a position corresponding to the position value in the Z direction transmitted from the control unit and corresponds to a position value of an XY plane that is a plane in the vertical direction from the Z direction And a beam adjuster including a scan head for causing a laser irradiator to be positioned at a position where the laser irradiator is positioned.

Further, the beam adjusting section may further include a light collecting section positioned on a side where the laser is irradiated to the outside.

Also, the irradiation of the laser can be irradiated in one unit of nanosecond, picosecond, and femtosecond to form a predetermined pattern.

A shape recognition unit for recognizing a shape of a surface of a posterior capsule from which an opaque first fluid is extracted and exposed; And a laser irradiating part for irradiating the posterior capsule with a predetermined pattern, the laser irradiation part being controlled by a control part for processing information of a shape recognized by the shape recognizing part, A posterior patterning device is provided which is fabricated so that turbid water is not proliferated, but is formed adjacent to the edge of the posterior.

The pattern may include one or more irregularities that are processed by a laser and formed independently.

Further, the pattern may include a plurality of concavities and convexities that are processed by a laser and are connected to each other.

Further, the pattern may be formed from the edge of the posterior to the center.

Further, the shape recognizing unit can transmit to the control unit a three-dimensional shape in which three-dimensional distortion including two-dimensional distortion in the XY plane of the posterior capsule and distortion in the Z direction perpendicular to the XY plane is corrected.

The laser irradiation unit may further include: a laser generation unit for generating a laser; A beam expander through which the laser generated from the laser generating portion passes; And a laser focusing unit that receives the laser beam passed through the beam adjusting unit and positions the laser irradiating unit in a position corresponding to the position value in the Z direction transmitted from the control unit and corresponds to a position value of an XY plane that is a plane in the vertical direction from the Z direction And a beam adjuster including a scan head for causing a laser irradiator to be positioned at a position where the laser irradiator is positioned.

Further, the beam adjusting section may further include a light collecting section positioned on a side where the laser is irradiated to the outside.

Also, the irradiation of the laser can be irradiated in one unit of nanosecond, picosecond, and femtosecond to form a predetermined pattern.

One embodiment of the present invention can provide a patterning apparatus and method for preventing posterior capsular opacity that can prevent a posterior disease after an eye disease treatment by forming a pattern on an intraocular lens to block cell proliferation that causes eye diseases .

An embodiment of the present invention provides a patterning device and method for preventing posterior capsular opacity that can prevent secondary disease after eye disease treatment by forming a pattern on the intraocular lens to induce cell proliferation that causes eye disease in a predetermined specific direction, Can be provided.

An embodiment of the present invention provides a patterning apparatus and method for preventing post-turbid opacity after precise processing of an object to be processed by processing a pattern formed on an artificial lens through a laser of a micro-meter or a nano-meter unit .

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a cross-sectional view of an eyeball to be patterned by a posterior capsule patterning device according to an embodiment of the present invention;
FIG. 2 is a view illustrating taking out a first lens before performing a posterior capsule patterning according to an embodiment of the present invention;
FIG. 3 illustrates recognition of the shape of the posterior capsule by the shape recognition unit of the posterior capsule patterning apparatus according to the embodiment of the present invention,
4 and 5 are views showing an example of a process of recognizing a shape of a posterior capsule according to an embodiment of the present invention;
FIG. 6 is a diagram illustrating a backpack patterning method according to an embodiment of the present invention;
FIG. 7 illustrates a backpack patterning method according to an embodiment of the present invention; FIG.
FIG. 8 illustrates a backpack patterning method according to an embodiment of the present invention,
FIG. 9 is a view illustrating that a pattern is processed in a posterior capsule by a laser irradiation unit according to an embodiment of the present invention,
10 is a view showing a machining part in which a pattern is machined according to an embodiment of the present invention
11 is a plan view of a pattern W according to an embodiment of the present invention,
12 is a view showing a depth and a width of a recess of a pattern W according to an embodiment of the present invention,
13 is a flow chart

Hereinafter, specific embodiments of the present invention will be described with reference to the drawings. However, this is merely an example and the present invention is not limited thereto.

In the following description, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear. The following terms are defined in consideration of the functions of the present invention, and may be changed according to the intention or custom of the user, the operator, and the like. Therefore, the definition should be based on the contents throughout this specification.

The technical idea of the present invention is determined by the claims, and the following embodiments are merely a means for effectively explaining the technical idea of the present invention to a person having ordinary skill in the art to which the present invention belongs.

The posterior capsule patterning device according to the present invention can be used in the process of implanting an implant such as an intraocular lens implant, a dental implant implant, or an orthopedic implant implant. Meanwhile, at least one of a micro pattern and a nano pattern, which affects cell alignment and movement direction in a living body, may be patterned, including a laser generator and a beam controller. Hereinafter, the present invention will be described as an example of controlling the propagation direction of cells forming the turbid body in the process of implanting the intraocular lens.

1 is a cross-sectional view of an eye 100 to be patterned by a posterior capsule patterning device according to an embodiment of the present invention.

1, an eyeball 100 to be patterned by a posterior capsule patterning apparatus includes a cornea 140, a lens 110, a phantom 130, an iris 150, a ciliary body 160, and a body 120 . ≪ / RTI > Herein, the lens 110 allows the light to be recognized as visual information by using the? P force while the light is incident. However, in some cases, the lens 110 may be difficult to perceive normal visual information because the part where the light is incident becomes turbid due to epithelial cell proliferation or proliferation of turbid substances. In order to overcome this phenomenon, it is possible to artificially replace the opaque lens 110. At this time, epithelial cells that proliferate nuclear cells or opacity remain in the eye, and after the lens 110 is artificially replaced, So that normal time information can not be recognized.

Accordingly, in order to prevent the proliferation of the epithelial cells, the present invention irradiates a posterior capsule (112 in FIG. 2) located on the back surface of the lens 110 to form a pattern capable of controlling the direction of proliferation of the epithelial cells. Here, the posterior capsule is a part of the lens capsule, and after the capsule lens 110 is taken out, the capsule located in the foreground and the capsule located in the back are described as capsules in the lens capsule accommodating the lens 110.

Hereinafter, the step of taking out the lens 110 from the eyeball 100 to the step of patterning the posterior capsule (112 of FIG. 2) will be described, and the configuration of the device for laser processing in the posterior capsule (112 in FIG. 2) Explain it.

The first lens 10 and the second lens 20 are referred to as a first lens 10 and a second lens 20 and the first lens 10 includes a lens 110, And the second lens 20 refers to the lens 110 which is newly replaced in the eyeball after replacement.

FIG. 2 is a view showing taking out the first lens 10 before performing the posterior capsule patterning according to the embodiment of the present invention.

Referring to FIG. 2, the first lens 10 can be taken out of the eye 100. For example, the take-out device 10 may be inserted through the opening formed by partially cutting the cornea 140 of the eyeball 100, and the lens 110 may be removed by the take-out device 10. The removal can be removed from the eye 100 through a method such as peeling and suction.

When the first lens 10 is taken out, the eye 100 may be exposed to the outside of the posterior capsule 112. The first lens 10 having a curved surface may be formed as a curved surface corresponding to the posterior capsule 112 as a seating point. Since the posterior capsule 112 is a part of the human body and has a different area and curvature for each individual, a process of recognizing the shape is required in order to obtain the surface information of the posterior capsule 112. For example, surface information of the posterior capsule 112 can be obtained through a three-dimensional scan.

The surface information of the posterior capsule 112 may be direct background information on the irradiation information of the laser to be irradiated to the posterior capsule 112. Next, with reference to FIG. 3, a description will be given of a shape recognition process for obtaining surface information of the posterior capsule 112 as the background information.

FIG. 3 is a view showing recognition of the shape of the posterior capsule 112 by the shape recognizing part 200 of the posterior capsule patterning device according to an embodiment of the present invention, and FIGS. 4 and 5 illustrate an embodiment of the present invention FIG. 2 is a view showing an example of a process of recognizing the shape of the posterior capsule 112 by the shape recognition unit 200.

Referring to FIG. 3, the shape recognition unit 200 may emit a recognition wave or recognition light 201 toward the eyeball 100. Specifically, the shape recognition unit 200 emits recognition light or recognition light 201 for acquiring surface information of the posterior capsule 112 toward the posterior capsule 112 exposed after the first crystalline lens 10 is taken out .

Referring to FIG. 4, the shape recognition unit 200 may include a correction unit 210 and a recognition unit 220. The shape recognition unit 200 can sense the surface information of the posterior capsule 112 by emitting a recognition wave 201 to the posterior capsule 112 adjacent to the eyeball 100. [ At this time, since the focal distance of the shape recognition unit 200 with respect to the posterior capsule 112 should be sensed on the surface curved in the three-dimensional direction and moved to compensate different focal distances for each point, distortion correction on the XY plane as well as height Direction in the Z-axis direction can also be corrected.

In addition, surface information of the posterior capsule 112 recognized by the recognition unit 220, which may be in the form of a lens, may be transmitted to the corrector 210. In the recognizing unit 220, the surface information of the posterior capsule 112 measured based on the focus of the lens and the two-dimensional plane, i.e., the XY plane, may be distorted in the process of recognizing the surface information. The correcting unit 210 can correct the distorted information and correct the distance in the vertical direction Z-axis direction from the XY plane. The Z-axis direction may be a height direction.

Referring to FIG. 5, an example of a step of recognizing the shape of the three-dimensional image of the posterior capsule 112 is as follows. (A) is to sense information in the Z-axis direction which is the height of the surface, Correction step. (c), and (d) is a state in which the step (a) is finely set so that the step (b) is further refined to increase the precision. (c) and (d), it is possible to move the laser irradiation unit 300 which can process the laser beam by compensating for the distortion on the XY plane and the distortion in the Z axis direction.

FIG. 6 is a view illustrating a backpack patterning method according to an embodiment of the present invention.

Referring to FIG. 6, the laser beam generated by the laser generator 310 passes through the beam expander 320 and is transmitted to the beam controller 330. The z-axis of the laser beam transmitted to the beam adjusting unit 330 is adjusted by the multimic focusing module 331, and the x-axis and the y-axis of the laser beam can be adjusted by the scan head 332.

FIG. 7 is a view illustrating a posterior patterning method according to an embodiment of the present invention.

Referring to FIG. 7, the size of the laser beam irradiated to the other x-axis and y-axis fields (that is, the imaging plane) of the surface height of the posterior bag 112 as a three-dimensional processing target may be the same. The size of the x-axis and the y-axis that can be scanned is determined according to the specification of the focusing lens of the light condensing portion 50, and thus the range of the z-axis can be determined. When the field size of the x-axis and the y-axis is 120 mm x 120 mm, the focus range in the Z-direction may be 8 mm. Also, the z-axis focus range may be 41 mm when the scanning range of the x- and y-axes is 180 mm x 180 mm, and the z-axis focus range may be 202 mm when the scanning range of the x- and y-axes is 300 mm x 300 mm. That is, in accordance with the three-dimensional pattern data of the three-dimensional surface inputted to the control section (400 in FIG. 8), the dynamic focusing module 331 calculates the z-axis corresponding to the x- Can be adjusted.

FIG. 8 is a view illustrating a post-baking patterning method according to an embodiment of the present invention.

8, a laser patterning apparatus for a three-dimensional object to be processed according to the present invention includes a laser generating unit 310, a beam expander 320, a beam adjusting unit (not shown) for fine patterning on the surface of the three- 330, a light collecting unit 350, a shape recognizing unit 360, and a control unit 400.

The laser generating unit 310 may generate a laser beam for patterning. Specifically, the laser generating unit 310 may use a pulsed laser source. Accordingly, the laser generating unit 310 can generate one of a laser beam of nanosecond, picosecond, or femtosecond. For example, the femtosecond laser beam may be a microwave laser having a pulse duration of 1 to 1000 femtoseconds. Specifically, the laser generating unit 310 may generate a pulsed laser beam having a pulse duration within a femtosecond range. Here, the pulse repetition rate may be in the range of two to about three kHz, or in the range of MHz. The wavelength of the laser beam can be all of the laser wavelengths located in the ultraviolet region from the infrared region. For example, ultraviolet wavelength, green wavelength, ultraviolet wavelength, and the like.

A laser patterning apparatus for a three-dimensional object to be processed according to an embodiment of the present invention can pattern a pattern having a width and a depth in units of nanometers on the surface of a three-dimensional posterior bag 112. By varying the laser wavelength according to the designed pattern size, various pattern sizes can be realized. For example, when the three-dimensional object to be processed is the posterior capsule 112 which is a part of the living body, a laser beam is irradiated to the entire surface of the object to be processed having a diameter of 10 mm or more (preferably, 12 mm) Can be generated. That is, in the laser patterning apparatus for a three-dimensional object to be processed according to the embodiment of the present invention, the wavelength of the laser is converted to have a short wavelength in the ultraviolet region and used to overcome the diffraction limit of the light collecting portion 350, Can be implemented.

The laser beam generated by the laser generating unit 310 may be a pulsed femtosecond laser beam and may pass through the beam expander 320 and the beam adjusting unit 330.

The beam expander 320 can adjust the size of the laser beam generated by the laser generating unit 310. Specifically, the beam expander 320 can enlarge or reduce the laser beam. In addition, the beam expander 320 can generate a laser beam as a collimated beam having less scattering or concentration. Accordingly, the laser beam generated by the laser generating unit 310 can be generated as a collimated beam while scaled and enlarged or reduced through the beam expander 320. The size of the laser beam processed in the beam expander 320 may be the size of the laser beam incident on the lens at the last stage of the laser patterning device of the three-dimensional object to be processed according to the embodiment of the present invention. The beam expander 320 may change the diameter of the laser beam generated by the laser generating unit 310 and output a modified laser beam. The beam expander 320 may be manually or automatically adjustable.

In addition, various optical elements such as a polarizing plate, a half-wave plate, a splitter, a filter, and a shutter can be further disposed.

The beam adjuster 330 can adjust the focus height and the focal position of the laser beam that can be irradiated to the three-dimensional object. The beam adjusting unit 330 may include a dynamic focusing module 331 and a scan head 332. [ The dynamic focusing module 331 of the beam adjusting unit 330 can adjust the focus height of the laser beam and the scan head 332 adjusts the focus position of the laser beam along the surface of the posterior bag 112, .

The dynamic focusing module 331 can adjust the focal position of the laser beam passing through the light collecting part 350 according to the three-dimensional machining data. Specifically, the dynamic focusing module 331 may include two lenses. That is, the dynamic focusing module 331 may include a first lens (not shown) and a second lens (not shown). The distance between the first lens and the second lens can be adjusted to control the divergence and convergence of the laser beam passing through the dynamic focusing module 331 so that the focus of the laser beam passing through the condensing part 350 can be adjusted.

In other words, the dynamic focusing module 331 can adjust the focal height of the laser beam via the beam adjuster 320, i.e., the z-axis position of the focus. The dynamic focusing module 331 adjusts the z-axis position of the laser beam, that is, the focus height of the laser beam, by adjusting the convergence and divergence of the laser beam via the beam expander 320. [

The dynamic focusing module 331 can irradiate the laser beam by adjusting the distance of the laser beam emitted to the scan head 332 by driving a motor (not shown) that reciprocates horizontally. For example, when the motor is horizontally reciprocating, when the dynamic focusing module 331 moves to the left, the focal point of the laser beam moves away from the three-dimensional surface, so that the laser beam can move upward on the z axis . Therefore, the height of the laser beam can be shortened. Conversely, when the dynamic focusing module 331 moves to the right side, the laser beam approaches the surface of the posterior capsule 112, so that the focus of the laser beam can move downward on the z axis. Therefore, the height of the laser beam can be increased. Therefore, the focal position of the laser beam incident on the surface of the posterior capsule can be controlled in the z-axis direction.

It is possible to perform patterning along the height of the three-dimensional shape of the surface of the posterior capsule 112 through the dynamic focusing module 331. For example, since the posterior capsule 112 has a curved shape according to the shape of the surface, the positions where the pattern should be patterned by the laser beam are different in height (i.e., z axis) along the respective x and y axes . Adjustment of the position of the focal point of the laser beam through the dynamic focusing module 331 on the z axis can uniformly perform patterning corresponding to different z axis positions for respective x axis and y axis coordinates. In addition, patterning can be performed with nano size to micro size line width. The dynamic focusing module 331 can move each of the lenses included in the optical system or the movement of the internal optical system. Accordingly, high-speed control of the height of the laser beam in real time is possible, thereby increasing the uniformity of the line width on the surface of the three-dimensional object and improving the productivity.

The x-axis and y-axis focal positions of the laser beam whose z-axis focal position is adjusted by the dynamic focusing module 331 can be adjusted by the scan head 332.

The scan head 332 can adjust the focus positions of the x and y axes of the posterior capsule 112. The scan head 332 includes an x-axis scan mirror (not shown) and a y-axis scan mirror (not shown) to perform two-dimensional scanning. the laser beam can be finely controlled in the x and y axis directions along the curved surface of the posterior capsule 112 through the x-axis scan mirror and the y-axis scan mirror.

The x-axis scan mirror and the y-axis scan mirror of the scan head 332 can reflect the laser beam in the direction for patterning the laser beam to irradiate the laser beam to a desired position on the surface of the posterior capsule 112. The x-axis scan mirror and the y-axis scan mirror are composed of a pair of scan mirrors in the form of a galvanometer, each of which deflects the laser beam in one of the axes crossing the xy plane, .

Accordingly, as described above, the beam adjuster 330 can adjust the focal height and the focal position of the laser beam. The laser beam is magnified or scaled down via the beam expander 320, and can be generated as a collimate beam and refracted in a controlled direction. The focal position of the laser beam passed through the beam expander 320 is adjusted by the dynamic focusing module 331 so that the x and y coordinates are adjusted by the scan head 332 to correspond to the surface of the posterior capsule 112 The focal position of the laser beam can be adjusted.

 A condenser 350 for condensing the femtosecond laser beam having passed through the dynamic focusing module 331 and the scan head 332 to the surface of the three-dimensional after-bag 112 may be disposed under the beam adjuster 330 have.

The light collecting part 350 can focus the laser beam. The light condensing unit 350 can condense the laser beam that has passed through the beam adjusting unit 330 and irradiate the surface of the posterior capsule 112 with a laser beam. The light collecting part 350 may include a telecentric F-theta lens or an F-theta lens. As a result, fine patterns of micro- or nano-sized units can be processed.

Through these configurations, at least one of various parameters such as the irradiation position of the laser beam, the focal distance, the pulse waveform of the laser beam to be output, the irradiation time, the divergence characteristic, and the astigmatism can be controlled.

The shape recognition unit 200 can recognize the shape of the three-dimensional object 1 to be processed. The shape recognition unit 200 may be disposed in a space different from the path of the laser irradiated from the laser irradiation unit 300. [ Also, the shape recognition unit 200 may be disposed in a path through which the laser beam is transmitted between the dynamic focusing module 331 and the scan head 332. The shape recognition unit 200 recognizes the surface of the three-dimensional curved shape of the posterior capsule 112 through the interference of light and can display the shape of the surface. The shape information of the posterior capsule 112 can be obtained through the interferometer using the refractive index and transmitted to the control unit 70. [

Furthermore, since the transparent three-dimensional object to be processed is transparent, it is difficult to recognize the height and the surface. Therefore, the three-dimensional information of the surface of the object is obtained through the interferometer using the refractive index, and the obtained information is matched with the drawing input to the control unit 400 to obtain a specific point (for example, The vertex of < / RTI > Accordingly, it is possible to grasp the position where the patterning process is performed by irradiating the laser beam. Through the shape recognizing unit 200, patterning can be flexibly performed on various surface structures.

The shape recognition unit 200 may recognize the shape of the three-dimensional object including the optical coherence tomography (OCT). For example, the surface of a three-dimensional object to be processed having a transparent curved shape is scanned three-dimensionally using a laser beam as a light source for inspection, and the coordinates of the three-dimensional surface shape are measured. Based on this data, Laser patterning can be performed on the surface. Here, the laser for laser patterning may be one of nanoseconds, picoseconds, or femtosecond lasers. For example, the wavelength of the laser beam may be greater than 100 nm and less than 10000 nm, and the repetition rate may be from 1 Hz to several hundred GHz.

It should be understood that the shape recognition unit 200 may recognize a shape of a three-dimensional object including a confocal microscope or a two-photon microscope. Here, the confocal microscope is a microscope using a confocal principle, and the shape recognition unit 200 including the same removes light that does not match the focus of the three-dimensional object to be processed in the laser beam and outputs only the light that coincides with the focus of the object The shape of the three-dimensional object to be processed can be recognized. Further, the shape recognition unit 200 can recognize the shape of the three-dimensional object including the two-photon microscope using two-photon absorption phenomenon.

On the other hand, in order to perform patterning on the surface of the three-dimensional object to be processed having a curved surface, the controller 400 inputs surface information received by the shape recognition unit and extracts focus position data of the x-, y-, and z- have. Based on this data, the two-dimensional focal position data of the x-axis and the y-axis can be controlled by the scan head 332. Further, the focus position data of the z axis can be controlled by the dynamic focusing module 332 to control the three-dimensional pattern data in real time. Therefore, it is possible to produce a micro pattern having a pattern width and a pattern depth in units of nanometers on the surface of an artificial lens.

Accordingly, the posterior-capsule patterning device according to the embodiment of the present invention can be used as a posterior-capsule-type imaging device including one of a laser interferometer, a confocal microscope, and a two-photon microscope, Dimensional surface profile information of the three-dimensional surface. Based on this, a laser beam is irradiated on the surface of a three-dimensional object to produce nano-sized pattern widths and pattern depths in a micro size. Of course, the laser for laser patterning may be one of nanoseconds, picoseconds, or femtosecond lasers.

Thus, when laser patterning is performed on the surface of the three-dimensional object 1, it is possible to overcome pattern centering defects, pattern breakage defects, pattern overlap defects, defective product surface defects, and the like.

FIG. 9 is a view showing that a pattern is processed in a posterior bag 112 by a laser irradiation unit 300 according to an embodiment of the present invention, and FIG. 10 is a view showing a processed part in which a pattern is processed according to an embodiment of the present invention It is a drawing.

Referring to FIG. 9, the laser irradiation units 300 and 300a may irradiate the laser 301 and the laser 301a to process the pattern in the posterior capsule 12. FIG. The laser processing may be formed at the edge of the circular posterior bag 112. For example, when the edge of the posterior capsule 112 is the edge of the posterior capsule 112, the edge of the posterior capsule 112 is located on the plane side (Z-axis direction) The irradiation unit 300 can be moved in a circular shape. The irradiated laser may reach the posterior capsule 112 by passing the laser through the cornea 140 if the cornea is not incised so as to open upward when the first lens 10 is taken out.

Referring to FIG. 10, the pattern W processed by the laser 301 is formed in the posterior capsule 112, and may be formed in the form of irregularities of predetermined line width, line width, and depth. The line width and line width of the irregularities may be, for example, 800 nm. The depth can be determined according to the output of the laser 301, but can be processed such that the shape of the irregularities including the grooves or recesses can be maintained.

11 is a plan view of a pattern W according to an embodiment of the present invention.

Referring to FIG. 11, the shape of the pattern W may be formed adjacent to an edge of the circular rear bag 112. The first pattern W1 may be formed independently from the first pattern W1 without the connection between the first patterns W1 when the first patterns W1 are formed. .

Furthermore, each first pattern W1 may be connected by a second pattern W2 connecting them. The shape of such a pattern may be a structure for determining the direction of proliferation of epithelial cells in order to prevent the turbid substances from gradually spreading toward the second lens 20 by the proliferation of the epithelial cells.

Therefore, the structure of the pattern W disclosed in Figs. 11 (a) and 11 (b) may include at least one of the first pattern W1 and the second pattern W2, Of course it is. Such a pattern W can determine the blocking and migration of the bacteria as a " proliferation pathway " that determines the direction of proliferation of epithelial cells. 12, the pattern W will be described by way of example of the depth and the width of the pattern W. FIG.

12 is a view showing the depth and width of the concave portion of the concavo-convex pattern W according to the embodiment of the present invention.

Referring to FIG. 12, the recesses included in the pattern W may have a width of from 83 to 228 m, and a depth of the recess may be 70 to 223 m.

The cross-sectional shape of the pattern may be a predetermined shape, and may be changed according to RIDGE, GROOVE, DEPTH.

In addition, the planar side of the pattern may be a shape including at least one of a circle, a comb, an arc, and a nano-surface.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, but, on the contrary, . Therefore, the scope of the present invention should not be limited to the above-described embodiments, but should be determined by equivalents to the appended claims, as well as the appended claims.

1: take out machine
10: First lens
20: Second lens
100: eyeball
110: lens
111:
112: posterior capsule
120: vitreous body
130: Shimada
140: cornea
150: iris
160: ciliary body
170: pupil
200:
201: Recognition wave
210:
220:
300: laser irradiation unit
301: Laser
310: laser generator
320: beam expander
330: beam regulator
331: Dynamic Focus Module
332: scan head
350: Collector
400:
W: pattern
W1: 1st pattern
W2: Second pattern

Claims (16)

The first lens is taken out from the eyeball,
The shape recognition unit recognizes the three-dimensional shape of the shape recognition unit with respect to the posterior capsule as a space side from which the first lens is inserted,
Transmits the recognized three-dimensional shape to the control unit,
Dimensional shape of the posterior capsule to the laser irradiation unit from the control unit,
Wherein the laser irradiating part irradiates the laser with the laser beam according to the three-dimensional shape received from the controller to form a predetermined pattern in the posterior capsule.
The method according to claim 1,
The pattern may be,
Wherein at least one unevenness processed by the laser and formed independently is included.
The method according to claim 1,
The pattern may be,
And a plurality of concavities and convexities that are processed by the laser and are connected to each other.
The method according to claim 1,
Wherein the pattern is formed to be centered from an edge of the posterior capsule.
The method according to claim 1,
The shape recognition unit
Dimensional shape including the two-dimensional distortion in the XY plane of the posterior capsule and the three-dimensional distortion including the distortion in the Z direction in the vertical direction from the XY plane is transmitted to the control unit.
The method according to claim 1,
The laser irradiation unit
A laser generator for generating the laser;
A beam expander through which the laser generated from the laser generating unit passes; And
A dynamic focusing module that receives the laser beam passed through the beam adjusting unit and positions the laser irradiating unit in a position corresponding to a position value in the Z direction transmitted from the controller, And a beam adjuster including a scan head for positioning the laser irradiator in a position corresponding to the position value.
The method of claim 6,
Wherein the beam adjusting section further comprises a light collecting section located on a side where a laser is radiated outward.
The method according to claim 1,
The irradiation of the laser is carried out,
Nanosecond, picosecond, and femtosecond to form the predetermined pattern.
A shape recognition unit for recognizing a shape of a surface of a posterior capsule from which an opaque first fluid is extracted and exposed; And
And a laser irradiating unit for irradiating the posterior capsule with a predetermined pattern by being controlled by a control unit for processing information of the shape recognized by the shape recognizing unit,
The pattern may be,
Wherein the second lens is disposed in place of the first lens so that the opacity is not propagated to the second lens and is formed adjacent to an edge of the rear bag.
The method of claim 9,
The pattern may be,
Wherein at least one unevenness processed by the laser and formed independently is included.
The method of claim 9,
The pattern may be,
And a plurality of concavities and convexities that are processed by the laser and are connected to each other.
The method of claim 9,
Wherein the pattern is formed from the edge of the posterior to the center.
The method of claim 9,
The shape recognition unit
Dimensional shape including the two-dimensional distortion in the XY plane of the posterior capsule and the three-dimensional distortion including the distortion in the Z direction in the vertical direction from the XY plane to the control unit.
The method of claim 9,
The laser irradiation unit
A laser generator for generating the laser;
A beam expander through which the laser generated from the laser generating unit passes; And
A dynamic focusing module that receives the laser beam passed through the beam adjusting unit and positions the laser irradiating unit in a position corresponding to a position value in the Z direction transmitted from the controller, And a beam adjuster including a scan head for causing the laser irradiator to be positioned at a position corresponding to the position value.
15. The method of claim 14,
Wherein the beam adjusting section further comprises a light collecting section located on a side where the laser is irradiated to the outside.
The method of claim 9,
The irradiation of the laser is carried out,
Nanoseconds, picoseconds, and femtoseconds to form the predetermined pattern.

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