KR20190048617A - Breast milk analyzer - Google Patents

Abstract

The present invention relates to a breast milk analyzing device and, specifically, to a breast milk analyzing device which is for non-destructive and rapid analysis of a breast milk sample using infrared spectrometer. A sample container having a dark room effect is mounted on a side of a reflection module (including broadband tungsten filament lamp and collection lens) such that the light irradiated from the infrared spectroscope is passed through the breast milk so as to be reflected, thereby being capable of blocking light from another exterior and improving the accuracy of analyzing the breast milk.

Description

BREAST MILK ANALYZER

The present invention relates to a breast milk analyzing apparatus, and more particularly, to a breast milk analyzing apparatus which is capable of rapidly analyzing a breast milk sample nondestructively using an infrared spectroscope, a sample container having a darkroom effect on the side of a reflection module (including a broadband tungsten filament lamp and a collecting lens) To a breast-milk analyzer capable of increasing the precision of breast-milk analysis by allowing light emitted from an infrared spectroscope to be transmitted through breast milk to be reflected, and blocking light from other outside.

In general, the breast milk analyzer is almost identical in structure to the milk analyzer, so the milk analyzer will be described. In managing the quality of milk, various measurement equipments are used to measure the components related to quality discrimination. The measurement data obtained at this time is used as a criterion for distinguishing milk quality. BACKGROUND ART [0002] Milk quality analysis apparatuses for measuring components such as milk protein and lactose, which are conventionally used for milk quality discrimination, are generally equipped with a wavelength band of 400 to 2500 nm and are used for scanning a wavelength ranging from 400 to 2500 nm And a grating, so that the measurement time is very long and the operation method is complicated.

Conventionally, the milk quality analyzing apparatus is configured to be suitable for a laboratory, so that it can be used as a laboratory analyzing apparatus. However, since the analyzing apparatus for the field is very sensitive and can not be used, the sample cell is 1 mm, Measuring methods are also very difficult. In addition, since the amount of the measurement sample to be introduced is small, it is troublesome to measure the milk in various parts in order to measure various components. Conventionally, the equipment for discriminating milk quality is an expensive laboratory equipment. There is a lot of problems in the field of supply such as the need to have a laboratory for.

Korean Patent Laid-Open Publication No. 2009-0077992 discloses an apparatus and method for analyzing milk quality in the field. The milk quality analyzing apparatus includes a monitor for outputting measured data, a power button for on / off of a power source, and an operation button for a run A body mounted on the side surface and having a cell introduction hole into which a sample cell is inserted at an upper end; A lamp power source mounted inside the main body and operated when the operation button is turned on; A lamp fixing bracket mounted inside the main body and having a plurality of halogen lamps connected to the lamp power source to generate beams; A sample fixing unit mounted on the inside of the lamp fixing bracket in correspondence with the position of the cell introduction hole and in which the sample cell is seated and fixed; A filter bracket mounted on a side of the lamp fixing bracket and having slits formed on both sides thereof to allow a predetermined amount of beam to pass therethrough; a rotation plate mounted on the inside of the filter bracket with a plurality of interference filters mounted thereon; A monochromator configured to include: A detector mounted on the rear side of the filter bracket to detect monochromatic light incident on the filter bracket at a predetermined amount; And an arithmetic processing unit connected to the detector, for converting the electrical signal output from the detector into data and transmitting the data to the monitor.

However, such a conventional technique has the effect of simultaneously measuring various components of milk by applying a monochromator using interference filters having different wavelength bands and increasing the amount of milk sample at one time. However, Since the sample is immersed in the sample cell and is fixed to the sample fixing part, the light from the outside is not completely blocked. Therefore, there is a problem that the light from the outside is transmitted in addition to infrared rays for analyzing the milk, and the analysis accuracy is lowered.

SUMMARY OF THE INVENTION It is therefore an object of the present invention to provide a method and an apparatus for detecting infrared light, And to provide a breast milk analysis device.

In order to achieve the above object, a breast-milk analyzing apparatus according to an embodiment of the present invention is a breast-milk analyzing apparatus that generates infrared rays, transmits them to a breast milk sample, and receives and analyzes reflected infrared rays. And a sample container having a drawer shape type which is transmitted through the breast milk sample to be reflected and is shielded from other external light.

A breast milk analysis apparatus according to an embodiment of the present invention includes a reflection module having a pair of upper and lower broad band tungsten filament lamps for generating infrared rays and a collecting lens for collecting reflected infrared rays through a breast milk sample; An input slit for adjusting the amount of infrared rays collected by the collecting lens to focus the infrared rays; A collimator lens for collimating light passing through the input slit; A diffraction grating and a focusing lens for dispersing the collimated light through the collimator lens into a plurality of wavelengths; A wavelength selector for selecting light of a predetermined wavelength among lights of a plurality of wavelengths dispersed by the diffraction grating and the focusing lens to spread horizontally; A collection optics for collecting light passing through said wavelength selector; A single photon detector for detecting a single photon of light collected by the collecting optics, and an A / D converter for converting the single photon detected by the single photon detector to a digital signal.

In the breast milk analyzing apparatus according to the above embodiment, the sample container may include a connection portion having an upper portion on the side of the reflection module, a vertically opened portion, a surface on which a light shielding film for blocking light is applied, A sapphire sample window W is formed on an upper surface of the sapphire sample window so as to transmit infrared rays radiated from above, and the sapphire sample window is opened on the left side and the sapphire sample window, A body to which the body is applied; And a breast-receiving groove for receiving a breast-milk sample at a position orthogonal to the sapphire sample window at the time of inserting, wherein the breast-receiving groove is inserted through the opened left side of the main body, and a rectangular parallelepiped shape A sample receiving part of the sample holder.

In the breast-milk analyzing apparatus according to the above embodiment, the light reflecting film applied to the sample storage portion may be white.

In the breast milk analyzing apparatus according to the above embodiment, the sample storage portion may be made of plastic.

According to the breast-milk analyzing apparatus according to the embodiment of the present invention, a sample container containing a breast-milk sample, the generated infrared rays being transmitted through the breast-milk sample to be reflected, As a result, only the infrared rays for the breast milk analysis can be accurately entered into the collecting lens, thereby improving the accuracy of breast milk analysis.

In addition, the sample storage part is coated with a light reflecting film for reflecting light, and since the light reflecting film is white, it does not absorb light from the outside but only passes through the sapphire sample window to reflect the light transmitted through the milk sample, It passes through the sample window and is incident accurately on the collecting lens of the breast milk analyzer.

Furthermore, since the sample storage portion is made of plastic, it is easy to manufacture the sample storage portion in a single use, and thus an accurate analysis of the milk sample can be performed.

1 is a schematic block diagram of a breast milk analysis apparatus according to an embodiment of the present invention.
Fig. 2 is a configuration diagram of the sample container of Fig. 1. Fig.
3 is a perspective view of the sample storage portion of Fig.

Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.

FIG. 1 is a schematic configuration diagram of a breast milk analysis apparatus according to an embodiment of the present invention, FIG. 2 is a configuration diagram of the sample container of FIG. 1, and FIG. 3 is a perspective view of the sample storage section of FIG.

1 to 3, a breast milk analyzer according to an embodiment of the present invention includes a sample container 10, a reflection module 20, an input slit 25, a collimate lens 30, a diffraction grating 40, a focusing lens 50, a wavelength selector 60, a collection optics 70, a single photon detector 80 and an A / D converter 90.

The sample container 10 is mounted on the side of the reflection module 20 and receives infrared light from the reflection module 20 (or simply referred to as light for simplicity of explanation) to receive the breast milk sample and transmit it through the breast milk sample It has the form of a drawer that blocks light from other outside.

More specifically, the sample container 10 includes a connecting portion 12, a main body 14, and a sample storage portion 16, as shown in Figs. 2 and 3.

The connection part 12 is fitted on the side of the reflection module 20 and serves to connect the main body 14 to the breast-milk analysis device. The connection part 12 is opened upward and downward (that is, vertically opened), is inclined to be coupled with the side of the reflection module 20, and light passes through the connection part 12. The connection part 12 is provided with a light shielding film for shielding light from the surface, so that light can not be incident from the outside, and only the infrared rays irradiated from the reflection module 20 or reflected through the sample of the milk sample passes through the inner space .

A sapphire sample window W is formed on the upper surface of the main body 14 so as to transmit infrared rays irradiated from above and a sample storage portion 16 is inserted and removed And the light shielding film is coated on the surface except for the sapphire sample window W to prevent light from being transmitted from the outside.

The sample storage portion 16 is inserted into and disconnected from the opened left side of the main body 14 and is formed with a milk receiving groove 16a for receiving a milk sample at a position orthogonal to the sapphire sample window W upon insertion, A light reflecting film is applied to the surface and reflects light. It is made of plastic and has a rectangular shape. The sample compartment 16 is made disposable for accurate measurement of the milk sample. In the particular implementation depicted in the figures, the milk sample is placed in front of the sapphire sample window (W). During the scan, the breast milk sample absorbs a certain amount of infrared light and diffuses the unabsorbed light back into the system. The amount of light absorbed at each wavelength depends on the molecular composition of the material and is a chemical fingerprint specific to the material

The reflection module 20 includes two lens-end broadband tungsten filament lamps 21 and 21 'for generating infrared rays and a collecting lens 23 for collecting reflected infrared rays through the milk sample. The reflection module 20 operates to collect diffuse reflected light in the slit 25 and to illuminate the breast milk sample according to the angle so that the mirror reflection is not collected.

The broadband tungsten filament lamps 21, 21 'are designated as lens end lamps because the shear of the glass bulb is formed from a lens that directs more light from the filament to the sample test area.

The collecting lens 23 forms a slit image in the wavelength selector 60.

The input slit 25 focuses the diffraction grating 40 by adjusting the amount of infrared light collected by the collecting lens 23. [ The size of the input slit 25 is selected to balance the SNR of the spectrometer with the wavelength resolution. The input slit 25 has, for example, a width of 25 mu m and a height of 1.8 mm.

The collimator lens 30 collimates the light passing through the input slit 25, passes through a waveguide filter of length 885 nm, and then reaches the reflective diffraction grating 40.

The diffraction grating 40 couples with the focusing lens 50 to disperse the collimated light through the collimate lens 30 into a plurality of wavelengths.

The wavelength selector 60 selects light of a plurality of wavelengths emitted by the diffraction grating 40 and the focusing lens 50 to emit light horizontally.

The wavelength selector 60 has a wavelength of 900 nm at one end and a wavelength of 1700 nm at the other end. All other wavelengths are sequentially dispersed. When the particular DMD column of the wavelength selector 60 is selected to be on or tilted to the + 17 ° position, the light is reflected by the selected column and directed to the collection optics 70.

The collecting optics 70 serves to collect the light passing through the wavelength selector 60.

The single photon detector 80 serves to detect a single photon of light collected by the collection optics 70.

The A / D converter 90 converts an analog signal output from the single photon detector 80 into a digital signal.

On the other hand, the wavelength selector 60 moves the selected wavelength away from the bottom of the light engine and the detector optical path so that all other DMD columns selected to be off or inclined to the -17 DEG position do not interfere with the selected wavelength measurement. The DLP NIRscan Nano slit image of the wavelength selector 60 to allow mechanical tolerances in the position of the slit 25, the angle of the diffraction grating 40 and the position of the wavelength selector 60 is less than 10% And is excessively filled in the orthogonal axis. Resulting in approximately (1700 - 900 nm) / (854 * 0.8 pixels) = 1.17 nm per pixel in the wavelength selector 60. At this time, calibration is performed between the wavelength and the column position in the wavelength selector (60). Since the number of rows of the wavelength selector 60 is generally not evenly divided according to the number of desired wavelength groups, the DLP NIRscan Nano stays the column width constant during scanning, but progresses the DMD array stepwise by a different amount than the column width.

The amount of this step depends on the desired width and number of patterns (wavelength points). For implementation details, see DLP Spectrometer Design Considerations. The reported wavelength of the DLP NIRscan Nano corresponds to the quantized DMD pixel at the center of the column width. Since the calibration parameters are unique in each DLP NIRscan Nano, the reported inter-unit wavelengths are different. To compare data with DLP NIRscan Nano at different reported wavelengths, insert them into a common wavelength position vector before comparing the different data sets. In general, interpolation is performed with a spline interpolation algorithm by oversampling the incoming wavelength vector. Smoothing algorithms such as Svitsky-Golay are generally applied after interpolation. Once all data sets are interpolated to a common wavelength vector, comparison between the various units is straightforward.

Hereinafter, the operation of the breast milk analyzing apparatus according to the embodiment of the present invention will be described.

First, the sample container 10 is mounted on the side of the reflection module 20, and after the breast milk sample is injected into the breast milk receiving groove 16a of the sample housing part 16, ).

When the infrared ray is irradiated from the side of the reflection module 20, the infrared ray is transmitted through the sapphire sample window W and is transmitted through the sapphire sample window W to the reflection module 20 side And the analysis of breast milk is made.

According to the breast-milk analyzing apparatus according to the embodiment of the present invention, the sample container accommodates a breast milk sample, the generated infrared rays are transmitted through the breast milk sample to be reflected, As a result, only the infrared rays for breast milk analysis can be accurately entered into the collecting lens, thereby improving the accuracy of breast milk analysis.

In addition, the sample storage part is coated with a light reflecting film for reflecting light, and since the light reflecting film is white, it does not absorb light from the outside but only passes through the sapphire sample window to reflect the light transmitted through the milk sample, By passing through the sample window, it can be accurately introduced into the collecting lens of the breast milk analyzer, which can improve the accuracy of breast milk analysis.

Furthermore, since the sample storage portion is made of plastic, it is easy to prepare the sample storage portion in a single use, so that accurate analysis of the breast milk sample can be performed.

Although the best mode has been shown and described in the drawings and specification, certain terminology has been used for the purpose of describing the embodiments of the invention and is not intended to be limiting or to limit the scope of the invention described in the claims. It is not. Therefore, those skilled in the art will appreciate that various modifications and equivalent embodiments may be made without departing from the scope of the present invention. Accordingly, the true scope of the present invention should be determined by the technical idea of the appended claims.

10: Sample case
12: Connection
14:
16: Sample collection section
W: Sapphire sample window
20: Reflection module
21, 21 ': Broadband tungsten filament lamp
23: Collecting Lens
25: slit
30: Collimator lens
40: diffraction grating
50: focusing lens
60: wavelength selector
70: collecting optics
80: single photon detector
90: A / D converter

Claims (5)

A breast-milk analysis device that generates infrared light to transmit to a breast milk sample and receives and analyzes the reflected infrared light:
And a sample container (10) containing a breast milk sample, wherein the generated infrared rays are transmitted through the breast milk sample to be reflected, and the other light from the outside is blocked, and having a drawer type. The method according to claim 1,
A reflection module 20 in which a pair of upper and lower broad band tungsten filament lamps 21 and 21 'for generating infrared rays and a collecting lens 23 for collecting reflected infrared rays through the breast milk sample are mounted;
An input slit 25 for adjusting the amount of infrared rays collected by the collecting lens to focus the infrared rays;
A collimator lens 30 for collimating light passing through the input slit;
A diffraction grating (40) and a focusing lens (50) for dispersing the collimated light through the collimator lens into a plurality of wavelengths;
A wavelength selector (60) for selecting light of a predetermined wavelength among lights of a plurality of wavelengths dispersed by the diffraction grating and the focusing lens to spread horizontally;
A collection optics (70) for collecting light passing through said wavelength selector;
A single photon detector 80 for detecting a single photon of light collected by the collecting optics; And
And an A / D converter (90) for converting the single photon detected by the single photon detector into a digital signal. 3. The method of claim 2,
The sample container
A connection part (12) having an upper part fitted to the reflection module side, a vertically opened part, a surface of which is coated with a light shielding film for blocking light, and is inclined;
A sapphire sample window W is formed on an upper surface of the sapphire sample window so as to transmit infrared rays radiated from above, and the sapphire sample window is opened on the left side and the sapphire sample window, A main body 14 to which is applied; And
A breast receiving groove 16a for receiving a breast milk sample is formed at a position orthogonal to the sapphire sample window at the time of insertion, and a light reflecting film for reflecting light is applied to the surface And a sample storage portion (16) in a rectangular parallelepiped shape. The method of claim 3,
Wherein the light reflecting film applied to the sample storage portion (16) is white. The method of claim 3,
The sample storage portion (16) is made of plastic.

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