KR20190047251A - Platform for sono-guided brain therapy - Google Patents

Abstract

The present invention relates to an ultrasound guided platform for brain treatment, which can drastically reduce errors due to conventional blind treatment by inserting a catheter into an accurate site while monitoring the state of the brain with ultrasound, to take a biopsy of the brain or the tissue around the brain, to allow blood or moisture to be aspirated and drained, or to enable vasodilation.

Description

{PLATFORM FOR SONO-GUIDED BRAIN THERAPY}

The present invention relates to a brain treatment platform under ultrasound guidance. More particularly, the present invention relates to a brain treatment platform for ultrasound guidance, and more particularly, The present invention relates to a method and a platform for drastically reducing errors due to conventional blind treatment by allowing water to be sucked and drained or blood vessels can be expanded.

With the development of science and technology, there have been many developments in the field of medical care, especially in medical devices including surgical instruments. In the past, doctors treated or treated according to their own experience, but in recent years, it has become possible to carry out complicated and difficult operations relatively easily and safely with the help of precise surgical instruments and medicines.

No matter how technologically advanced, there are still many homework problems to be solved in the technology for treating certain diseases including cancer and certain diseases such as the brain.

Particularly in the case of the brain, it is one of the areas where humans are most afraid of being treated, and it may be the most important part of human body parts. When a brain abnormality occurs in the human body, it is difficult to treat, and the catastrophic result will not allow minor mistakes in the treatment process.

Brain surgery is generally considered to be a very serious surgery and life-threatening operation, even if the pathology is minor.

It is a relatively simple operation during brain surgery. It is a relatively simple operation during brain surgery. When the water between the head bone and the brain surface becomes watery (dural saline species) (Subarachnoid hemorrhage). There is a burr hole drainage. When cerebral hemorrhage due to intracerebral hemorrhage or blood pressure causes blood to spread to the ventricle and cerebrospinal fluid flow in the ventricle is blocked (acute hydrocephalus) There is an external ventricular drainage. Extracranial drainage is similar to perforating drainage, except that the catheter penetrates the brain tissue and enters the ventricles.

In addition, there is a ventriculoperitoneal shunt that creates a pathway through the catheter between the ventricle of the head and the abdominal cavity, which is relatively common during hydrocephalus. Also, after general anesthesia, There is a craniotomy to remove brain lesions (hematoma, tumor, foreign body, etc.) after incision.

Recently, neurosurgery has been revolutionized by the introduction of surgical microscopes. Since the surgical microscope allows the surgeon to see the enlarged view of the surgical site from several times to several tens of times, the relationship between the surrounding tissue and the blood vessels can be grasped accurately, It can be used to minimize the possibility of vascular damage and is thus essential for almost all brain operations.

In these brain surgeries, the scalp of the surgical site is opened, a hole is made in the head bone, and the meningeal incision is made, the catheter is inserted through the hole, or even the brain tissue is punctured and the catheter is inserted into the ventricle.

As we all know, the brain has important blood vessels and nerves intertwined, so puncturing the head bone and incising the meningeal, then putting the catheter in the hole or puncturing the brain tissue and putting the catheter into the ventricle is a serious It must be an operation. However, until now, after the scalp of the surgical site has been incised, a hole in the head bone has been used to incise the brain or to puncture the brain tissue, depending on the doctor's personal experience. But no minor mistakes should be tolerated in the operation of the human brain.

Accordingly, the present invention proposes a method for monitoring the state of the brain through ultrasound and advancing the operation at an optimum position.

Further, the present invention provides a platform for inspecting the state of the brain with ultrasound and inserting the catheter into an accurate site to biopsy the tissue around the brain and the brain, aspirate and drain the blood or moisture, or expand the blood vessel. This paper proposes a method to dramatically reduce errors due to blind procedures according to the physician's experience.

Next, a brief description will be given of the prior arts that exist in the technical field of the present invention, and technical matters which the present invention intends to differentiate from the prior arts will be described.

Korean Registered Patent No. 0784117 (Dec. 4, 2007) relates to an ultrasound 24-hour brain monitoring device embedded in a skull and can perform ultrasound imaging and Doppler examination with a tip embedded in a drill hole formed in the skull An ultrasonic transducer having a diameter of 10 mm or less, a skull-bottomed ultrasonic transducer steering device fixed to a drill hole of the skull in a state of being attached to a distal end of the ultrasonic transducer to adjust the direction of the ultrasonic transducer, A steering device controller for controlling the ultrasonic transducer steering device, and an ultrasound image display device connected to the distal end of the ultrasonic probe for displaying a signal from the ultrasonic probe.

The prior art can monitor the cerebral blood flow state through the cerebral blood vessels through the Doppler examination, monitor the pathological state of the brain due to cerebral hemorrhage and cerebral edema through the ultrasound image, detect the brain condition requiring immediate treatment at an early stage, The present invention provides a method of monitoring the state of the brain through the ultrasonic wave of the present invention in terms of confirming the state of the brain through the Doppler test using ultrasonic waves, .

However, the present invention proposes a technical configuration for inspecting the state of the brain with ultrasound and inserting the catheter into an accurate site to biopsy the tissue around the brain and brain, to aspirate and drain blood or moisture, and to expand blood vessels Therefore, it is apparent that the technical features are different from the technology construction in which the state of the brain requiring treatment is detected early by performing the examination of the brain state using the ultrasound of the prior art for 24 hours.

Korean Patent No. 1271700 (May 30, 2013) discloses a device for cerebrospinal fluid drainage in a ventricle that easily inserts a ventricular catheter. The device includes a main body, a direction indicator that is screwed to the main body, and an arm As a technical feature.

The above-described prior art is to accurately position the EVD catheter in the anterior cerebral ventricle during cerebral outdoor cerebrospinal fluid drainage (EVD) or cerebrospinal fluid ventricular-abdominal short-circuit shunt operation (shunt surgery) by using brain external CSF drainage device for inserting the ventricular catheter There is some similarity with the construction of inserting the catheter of the present invention into the correct site in terms of precisely positioning the catheter in the frontal portion of the lateral ventricle.

However, the present invention provides a technique for monitoring the state of the brain through ultrasound and inserting the catheter into an accurate site to biopsy the tissue around the brain and the brain, to drain blood or moisture, There is a difference in the technical characteristics as compared with the technical construction in which a device capable of positioning the catheter at the frontal portion of the lateral ventricle of the prior art is provided.

That is, the prior arts disclose a configuration for confirming the state of the brain through Doppler examination using ultrasound, and a configuration for positioning the EVD catheter in the frontal portion of the lateral ventricle through a device for draining cerebrospinal fluid. However, , There is no description about a structure that can biopsy the tissue around the brain and the brain, aspirate and drain blood or moisture, or expand the blood vessel by performing insertion of the catheter while monitoring the state of the brain through the brain The technical differences are obvious.

The object of the present invention is to provide a platform for brain treatment under ultrasound guidance, which is created to solve the above-mentioned problems, and enables the operation to be performed at an optimal position while monitoring (monitoring) the state of the brain through ultrasound do.

In order to reduce errors due to blind procedures according to the experience of a physician, the present invention monitors ultrasound to monitor the state of the brain, inserts the catheter into an accurate site, biopsies tissues around the brain and brain, Another object of the present invention is to provide a platform for brain treatment under ultrasound guidance, which allows the inflow of water by sucking and draining or clogged blood vessels.

A brain treatment platform according to an embodiment of the present invention includes an ultrasound device installed in a burr formed by drilling a skull to perform brain surveillance and a catheter insertion support for inserting the catheter into a lesion site according to the monitoring of the ultrasound device And performing brain surveillance through the ultrasound device and performing brain tissue extraction for biopsy, aspiration of blood or moisture, expansion of blood vessels, or a combination thereof through the catheter .

In addition, the brain treatment platform may be configured to control ultrasonic generation, reception, steering, or a combination of the ultrasonic waves of the ultrasonic apparatus, analyze the ultrasonic signals input from the ultrasonic apparatus, and determine a path, an angle, And a control device for displaying ultrasound images of the brain state.

The controller may further include a communication interface for outputting an ultrasonic output control signal and a steering control signal to the ultrasonic device, receiving the ultrasonic signal from the ultrasonic device, and outputting the ultrasonic signal to the brain condition analyzer, A steering control unit for generating a steering control signal for steering a probe of the ultrasonic apparatus and outputting the steering control signal to the ultrasonic apparatus, an ultrasonic sensor for detecting an ultrasonic wave received from the ultrasonic apparatus through the communication interface unit, A brain condition analyzing unit for analyzing a signal to extract catheter insertion support information including a path, an angle, or a combination of the catheter to be inserted and an ultrasound image of a brain state; And a display unit And that is characterized.

The ultrasonic apparatus may further include a chamber coupled to the borehole, a probe disposed in the chamber for generating ultrasonic waves based on an ultrasonic output control signal received from the control device and radiating ultrasonic waves into brain tissue, A steering unit for performing pan and tilt driving of the probe on the basis of a steering control signal input from the control unit, and a controller for receiving an ultrasonic output control signal and a steering control signal from the controller, And a communication interface for transmitting the ultrasound signal received from the probe to the control device.

The ultrasonic apparatus further includes a handle member attached to or detached from the ultrasonic device. The ultrasonic device is attached to the burr formed in the skull after the handle member is attached, and when the installation of the ultrasonic device is completed The handle member is detached.

At this time, the chamber is formed with a soft material that penetrates the burr hole and contacts the dura mater of the brain, and is filled with the hydrogel to prevent damage or contamination of the brain tissue.

The steering unit may be separated and configured separately from the ultrasonic device, and may be connected to the probe through a wire. Then, the steering unit may perform the pan and tilt driving of the probe through the wire driving based on the control of the controller. do.

The catheter insertion support member may be formed of a pin having a U shape and a side corresponding to the catheter may be formed of a flexible material so that an angle of entry of the catheter inserted into brain tissue can be varied. do.

The catheter insertion support member is formed of a pin having a U shape and is formed by fixing a slope of one side corresponding to the catheter. A plurality of the catheter insertion support members are formed according to the entry angle of the catheter, The catheter is inserted into a specific lesion position while maintaining a fixed inclination through a catheter insertion support member having a slope corresponding to an entry angle of the catheter determined according to the ultrasonic receiving information of the apparatus.

The catheter insertion support member may have a guide groove formed on one side of the catheter, the guide groove being fitted into the catheter to support the catheter in a vertical direction.

According to another aspect of the present invention, there is provided a method for operating a brain treatment platform, the method comprising: installing an ultrasound device in a bucket formed by drilling a skull; operating the ultrasound device to operate the ultrasound device for monitoring the brain; A catheter insertion support member mounting step of coupling the catheter insertion support member to the ultrasound device based on the monitoring information of the ultrasound device and a catheter inserting step of supporting the insertion of the catheter into the lesion site through the catheter insertion support member, Performing brain surveillance through an ultrasonic device, performing brain tissue extraction for biopsy, aspiration of blood or moisture, expansion of blood vessels, or a combination thereof through the catheter.

The method for operating a brain treatment platform may further include the steps of generating a control signal including an ultrasonic output control signal for generating an ultrasonic wave of the ultrasonic device, a steering control signal for steering the probe of the ultrasonic device, or a combination thereof, A control signal generating and outputting step of outputting the ultrasonic signal to the ultrasound device; and a controller for analyzing the ultrasound signal input from the ultrasonic device and generating a control signal based on the analysis result, And an analysis and display step of displaying ultrasound images on the brain support and insertion support information.

As described above, according to the brain treatment platform under the ultrasound guidance of the present invention, the state of the brain is monitored with ultrasound, and the catheter is inserted into the correct site to biopsy the tissue around the brain and the brain, By diluting or clogging a clogged blood vessel, it is possible to drastically reduce the error due to the blind procedure according to the experience of the prior art physician.

In addition, the surgeon can monitor the state of the brain through the ultrasound, insert the catheter into the desired position, and then perform the brain surgery at the optimal position, which can greatly improve the accuracy of the operation, .

1 is a view for explaining the concept of a brain treatment platform under ultrasound guidance to which the present invention is applied.
FIG. 2 is a view schematically showing a configuration of a brain treatment platform under ultrasound guidance according to an embodiment of the present invention.
FIG. 3 is a schematic view showing an internal configuration of the ultrasonic apparatus of FIG. 2. FIG.
Fig. 4 is a detailed block diagram of the ultrasonic apparatus of Fig. 2. Fig.
FIG. 5 is a view for explaining a pull member used when inserting or releasing the buckle of the ultrasonic device of FIG. 2;
FIG. 6 is a schematic view of the structure of the catheter insertion support member of FIG. 2;
FIG. 7 is a detailed block diagram of the control apparatus of FIG. 2. FIG.
FIG. 8 is a flowchart illustrating an operation process of a method for operating a brain treatment platform under ultrasound guidance according to an embodiment of the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. Like reference symbols in the drawings denote like elements. Furthermore, specific structural and functional descriptions for embodiments of the present invention are presented for the purpose of describing an embodiment of the present invention only, and, unless otherwise defined, all terms used herein, including technical or scientific terms Have the same meaning as commonly understood by those of ordinary skill in the art to which the present invention belongs. Terms such as those defined in commonly used dictionaries are to be interpreted as having a meaning consistent with the contextual meaning of the related art and are to be interpreted as ideal or overly formal in the sense of the art unless explicitly defined herein .

FIG. 1 is a view for explaining the concept of a brain treatment platform under ultrasound guidance to which the present invention is applied, and FIG. 2 is a view schematically showing a configuration of a brain treatment platform under ultrasound guidance according to an embodiment of the present invention.

1 and 2, the brain treatment platform of the present invention comprises an ultrasound device 100, a catheter insertion support member 200, a catheter 300, a controller 400, and the like.

The ultrasonic device 100 is inserted into a burr hole drilled at a predetermined position of the skull and performs ultrasonic wave emission and reception for ultrasonic inspection on the basis of the control of the control device 400 to perform brain surveillance.

That is, the ultrasound device 100 monitors the blood flow state of the entire cerebral tissues and the main cerebral blood vessels in the cranial cavity. The surgeon inserts the catheter 300 into the correct region based on the monitoring information on the brain state, To perform accurate biopsy of the surrounding tissue, aspiration and drainage of blood or moisture, or surgery to expand a clogged blood vessel. Accordingly, it is possible to improve the accuracy of the surgery while drastically reducing the error due to the blind procedure according to the experience of the conventional physician.

At this time, the tip of the ultrasonic device 100 radiates ultrasonic waves into the brain based on the steering control of the control device 400 and the ultrasonic output control in a state in which the tip of the ultrasonic device 100 is directly in contact with the epidermis of the brain through the burr hole, And transmits the received signal to the control device 400.

The ultrasonic device 100 may be formed in various shapes such as a circular shape, a square shape, and a polygonal shape so that the ultrasonic device 100 can be easily inserted into a burr formed in the skull and inserted. In order to monitor a wide range of brain tissue, As shown in Fig.

A more detailed internal structure and configuration of the ultrasonic device 100 will be described with reference to FIGS. 3 and 4. FIG.

The catheter insertion support member 200 is coupled to one side of the ultrasound device 100 and functions to insert the catheter 300 into the lesion site according to the ultrasound reception information of the ultrasound device 100.

The catheter insertion support member 200 can be configured in two forms. For example, one side of the catheter 300 corresponding to the catheter 300 may be formed of a flexible material so that the angle of entry of the catheter 300 inserted into the brain tissue can be varied, And a plurality of the catheters 300 may be formed according to the entry angle at which the catheter 300 is inserted.

At this time, if the catheter insertion support member 200 is formed in a plurality of the catheter insertion support members 200 according to the entry angle at which the catheter 300 is inserted, the surgeon can determine the ultrasound The catheter 300 can be inserted into a specific lesion site while maintaining a fixed tilt (i.e., an insertion angle) using a catheter insertion support member 200 having a slope that matches the entry angle of the catheter 300. [

The catheter 300 is used for brain surgery such as external ventricular drainage and ventriculoperitoneal shunt, and is usually composed of a thin tube made of rubber or metal.

The catheter 300 is inserted into the lesion through the burr hole while being in contact with one side of the catheter insertion support member 200 through the side space of the ultrasonic device 100 inserted into the burr hole. At this time, the angle between the catheter 300 and the catheter insertion support member 200 is about 10 to 30 degrees.

That is, the catheter 300 connects the catheter insertion support member 200 with the ultrasound device 100 having the specific angle of entry set based on the patient's brain monitoring information through the ultrasound device 100 according to a doctor's operation The catheter 300 may be inserted into a lesion position in a state where the catheter 300 is in contact with one side of the catheter insertion support member 200 or may be inserted into one side of the catheter insertion support member 200 of a flexible material coupled to the ultrasound device 100 The catheter 300 is brought into close contact with the catheter 300 and then inserted into the lesion site while slightly changing the entry angle according to the operation of the doctor who confirms the brain information of the specific patient through the ultrasound device 100.

Accordingly, it is possible to perform biopsy of tissues around the brain and the brain, aspiration of blood or moisture in a specific brain tissue, etc., by using the catheter 300 inserted in a lesion position in the brain.

The controller 400 controls the overall operation of the ultrasonic apparatus 100 connected to the wired / wireless communication by generating, receiving, and steering ultrasonic waves. The controller 400 analyzes the ultrasonic signals input from the ultrasonic apparatus 100 based on the pre- The ultrasound image of the brain state is extracted and displayed on the screen so that the doctor or related worker can confirm it.

A doctor or an associated worker may connect the catheter insertion support member 200 of a flexible material to the ultrasound device 100 and contact the catheter insertion support member 200 with the catheter 300, The insertion angle of the catheter 300 can be slightly changed and inserted into the lesion site.

The controller 400 may analyze the ultrasound signal input from the ultrasound device 100 to generate catheter insertion support information including a path, an angle, or a combination of the catheter 300 insertion direction, The support information is displayed on the screen so that it can be checked by a doctor or related worker.

Accordingly, the physician or the related worker can select the catheter insertion support member 200 that assists in inserting the catheter 300 based on the catheter insertion support information. That is, a catheter insertion support member 200 having a corresponding angle is connected to the ultrasound device 100 based on catheter insertion support information including an entry angle to a lesion position where the catheter 300 is to be inserted, ) Can be accurately inserted into the lesion site.

In addition, the controller 400 can display the ultrasound examination results obtained by measuring the ultrasound waves in units of time in the ultrasound system 100 according to a user's request. The ultrasound waves can be changed little by the movement of blood vessels The inspection position can be automatically corrected. It is also desirable to control so that other signals in the vicinity can be automatically detected and measured when an ultrasound signal can not be measured at a predetermined position or an unexpected blood flow velocity is detected.

Meanwhile, when the ultrasound device 100 is inserted into the burr hole formed in the patient's skull, the state of the patient may be continuously monitored for a predetermined period of time.

In this case, the brain treatment platform of the present invention further includes a sensor in the vicinity of the ultrasonic device 100 to sense information on the temperature and pressure of the brain, and provides the sensed information to the control device 400 In addition to ultrasound imaging, changes in the patient's brain state can be continuously monitored. At this time, when the sensor is provided at the distal end of the catheter 300, the temperature, pressure, and the like of the lesion position into which the catheter 300 is inserted can be sensed.

In addition, when inserting the catheter 300 into the lesion site, the brain treatment platform of the present invention should not interfere with the FOV (field of view) of the ultrasound device 100 inserted into the burr hole. That is, the insertion of the catheter 300 is performed outside the tilt range of the ultrasonic device 100.

3 and 4 are views each showing an internal configuration and a detailed block configuration of the ultrasonic device 100 of FIG. 2, FIG. 5 is a view for explaining a handle member used for inserting or releasing a buffer hole of the ultrasonic device of FIG. 2 to be.

3 and 4, the ultrasonic apparatus 100 includes a chamber 110, a probe 120, a steering unit 130, a communication interface unit 140, and the like.

The chamber 110 is inserted and fixed in the burr hole and has a probe 120, a steering unit 130, and a communication interface unit 140 therein.

In addition, the side surface of the chamber 110, which is inserted and fixed to the borehole, is generally made of a steel material. The distal end portion of the chamber 110, which penetrates the borehole and contacts the dura mater of the brain, is formed of a soft material of a very thin membrane, So as to achieve good adhesion. In addition, radiation and reception of ultrasonic waves can be smoothly performed, and damage or contamination of brain tissue due to movement of the probe 120 can be prevented.

A hydrogel is filled in the inner space of the chamber 110 to facilitate the fan and tilt driving of the probe 120 and the emission and reception of ultrasonic signals.

The probe 120 includes an ultrasonic wave generating unit 122 and an ultrasonic wave receiving unit 124. The probe 120 processes ultrasonic wave radiation and reception based on the control of the controller 400 to perform brain monitoring.

That is, the probe 120 generates ultrasound through the ultrasonic wave generator 122 based on the ultrasonic wave output control signal received from the controller 400, And receives an ultrasonic wave through the ultrasonic wave receiving unit 124.

The steering unit 130 is coupled to the probe 120 and performs the pan and tilt driving of the probe 120 on the basis of the steering control signal input from the control unit 400 to control the position of the ultrasonic device 100 So that ultrasound emission and reception can be performed on the entire brain.

3, the steering unit 130 is provided in the form of a bracket that encloses a side surface of the probe 120 in the chamber 110. However, the present invention is not limited thereto, and the ultrasonic wave device The probe 120 is separated and configured separately from the probe 100 and connected to the probe 120 through a wire. Then, the probe 120 is subjected to fan and tilt driving through wire driving based on the control of the controller 400 It is possible to do.

The steering unit 130 may be an actuator or the like capable of controlling the steering angle of the probe 120 by 0.1 degree or more.

The communication interface unit 140 receives the ultrasonic output control signal and the steering control signal from the controller 400 and outputs the ultrasonic output control signal and the steering control signal to the probe 120 and the steering unit 130, And transmits a signal to the control device 400. [

5, the ultrasonic apparatus 100 may further include a grip member 150 attached to or detached from the ultrasonic apparatus 100. [

That is, after attaching the handle 150 to the upper portion of the ultrasonic device 100, the ultrasonic device 100 is inserted into a burr formed in the skull, and the installation of the ultrasonic device 100 is completed The pull tab 150 is detached. Also, when the ultrasonic device 100 is dismounted, the handle 150 may be attached to the upper portion of the ultrasonic device 100 and may be pulled out to be released. Accordingly, the doctor or the related worker can easily couple or release the ultrasonic device 100 to the buckle formed in the skull.

FIG. 6 is a view schematically showing the structure of the catheter insertion support member 200 of FIG.

As shown in the figure, the catheter insertion support member 200 is preferably formed of 'D' shaped pins, and the catheter insertion support member 200 may be formed of a flexible material (e.g., a left leg portion in FIG. 3) So that the angle of entry of the catheter 300 inserted into the brain tissue can be changed.

That is, after a physician or a related worker attaches the catheter insertion support member 200 of a flexible material to the ultrasound device 100, the catheter 300 is contacted with the catheter insertion support member 200, So that the catheter 300 can be inserted into the lesion position while slightly changing the entry angle of the catheter 300.

The catheter insertion support member 200 is formed by fixing a slope of one side of the catheter 300, which is different from that of the one-leg portion formed of a flexible material, as described above, A plurality can be formed for each entry angle.

That is, the catheter 300, based on the information of the catheter insertion support information (for example, the information including the path, angle, or combination of the catheter 300 inserted) generated by the control device 400 by a doctor or a related worker The catheter insertion support member 200 having the inclination angle of the entry angle inserted into the lesion position is selected and coupled to the ultrasonic device 100. Thereafter, the catheter 300 is contacted to the catheter insertion support member 200, So that the catheter 300 can be inserted into a lesion site.

A guide groove 210 is formed on one side of the catheter insertion support member 200 corresponding to the catheter 300 and is inserted into the catheter 300 to support the catheter 300 in a vertical direction Respectively.

7 is a detailed block diagram of the control device 400 of FIG.

The controller 400 includes a communication interface 410, an ultrasonic controller 420, a steering controller 430, a brain condition analyzer 440, a display unit 450, a storage unit 460, and the like. .

The communication interface unit 410 outputs a control signal including an ultrasonic output control signal, a steering control signal, or a combination thereof to the ultrasonic apparatus 100 connected to the communication, receives ultrasonic signals from the ultrasonic apparatus 100 And outputs it to the brain state analysis unit 440.

The ultrasonic control unit 420 generates an ultrasonic output control signal for generating ultrasonic waves in the probe 120 of the ultrasonic apparatus 100 and supplies the generated ultrasonic output control signal to the ultrasonic apparatus 100 through the communication interface unit 410. [ (100).

The steering control unit 430 generates a steering control signal for driving the panning and tilting of the probe 120 of the ultrasonic apparatus 100 and transmits the generated steering control signal to the ultrasonic apparatus 100 through the communication interface unit 410. [ 100).

The brain condition analyzing unit 440 analyzes the ultrasound signals received from the ultrasound device 100 through the communication interface unit 410 and analyzes the path, And outputs ultrasound images related to the brain state to the display unit 450. The catheter insertion support information and the ultrasound images related to the brain state are output to the display unit 450. [

The display unit 450 displays on the screen the catheter insertion support information and the brain state ultrasound image extracted by the brain state analyzing unit 440 so that a doctor or a related worker can immediately confirm the catheter insertion support information.

The storage unit 460 stores various operation programs for driving the ultrasound device 100 and the controller 400. The storage unit 460 stores information on the catheter insertion support information processed by the brain condition analyzing unit 440, Ultrasound images are divided into individual patients and stored.

Hereinafter, an embodiment of a method for operating a brain treatment platform under ultrasound guidance according to the present invention will be described in detail with reference to FIG. At this time, each step according to the method of the present invention may be changed in the use environment or the order by a person skilled in the art.

FIG. 8 is a flowchart illustrating an operation process of a method for operating a brain treatment platform under ultrasound guidance according to an embodiment of the present invention.

First, in order to monitor the brain state by inserting the catheter 300 into the tissue of the brain such as the ventricle, perform a biopsy of the tissue, or perform surgery for draining blood or moisture, a predetermined position of the patient's skull The drill is drilled to form a burr hole (S100).

In step S200, the ultrasound system 100 emits and receives ultrasound to monitor changes in the brain of the buckle formed in step S100. At this time, the ultrasonic device 100 is installed so that the tip of the ultrasonic device 100 penetrates the burr and directly contacts the epidermis of the brain. In order to facilitate the installation of the ultrasonic device 100, 150 is attached to the upper portion of the ultrasonic device 100 and then the ultrasonic device 100 is inserted into a burr formed in the skull while the pull tab 150 is gripped, When the installation is completed, the pull-tab 150 is detached.

After the ultrasonic apparatus 100 is installed in the burr hole through the step S200, the ultrasonic apparatus 100 starts operating based on the steering control and the ultrasonic output control of the controller 400 (S300). That is, the ultrasonic apparatus 100 for brain surveillance.

Then, the controller 400 receives the catheter insertion position information designated by the doctor or related worker (S400), receives the ultrasound signal reflected by the brain tissue by radiating the ultrasound into the brain, And extracts the catheter insertion support information including the path, angle, or combination of the catheter 300 and the ultrasound image related to the brain state, and displays the extracted ultrasound image on the screen (S500) .

Then, the doctor or the related worker combines the catheter insertion support member 200 on one side of the ultrasound device 100 based on the catheter insertion support information and the brain state ultrasound image displayed on the screen through step S500, The catheter 300 is inserted into the guide groove 210 provided at one side of the catheter insertion support member 200 in a state where the catheter 300 is in contact with the catheter 300 at step S600.

For example, when the catheter insertion support member 200 is formed of a flexible material corresponding to the catheter 300, a doctor or a related worker may insert the catheter insertion support member 200 into the ultrasound device 100, The catheter 300 is contacted to the catheter insertion support member 200 and inserted into the lesion site while slightly changing the entry angle of the catheter 300 while checking the ultrasound image.

When the catheter 300 is formed to have a fixed inclination by dividing one side of the catheter insertion support member 200 corresponding to the approach angle of the catheter 300, The catheter insertion support member 200 having the inclination angle of the entry angle into which the catheter 300 is inserted up to the lesion position is selected based on the catheter insertion support information generated by the control device 400 and is transmitted to the ultrasound device 100 After the catheter 300 is in contact with the catheter insertion support member 200, the catheter 300 is inserted into the lesion site.

If the catheter 300 is inserted into the correct lesion position in step S600, brain tissue extraction, aspiration of blood or moisture, blood vessel expansion, or a combination thereof is performed through the catheter 300 (S700 ).

As described above, since the present invention can monitor the state of the brain with ultrasound and insert the catheter into an accurate site to biopsy the tissue around the brain and the brain, draw blood or moisture into the bloodstream or expand the clogged blood vessel, The error caused by the blind procedure according to the physician's experience can be drastically reduced.

In addition, since the physician can insert the catheter precisely at the desired position and then perform the brain surgery at the optimum position, the accuracy of the operation can be greatly increased, which is very helpful in saving the patient's life.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, I will understand the point. Accordingly, the technical scope of the present invention should be determined by the following claims.

100: ultrasonic device 110: chamber
120: probe 130: steering part
140: communication interface unit 150: handle member
200: catheter insertion support member 210: guide groove
300: catheter 400: control device
410: Communication interface unit 420: Ultrasonic wave control unit
430: Steering control unit 440: Brain analysis unit
450: display section 460: storage section

Claims (12)

An ultrasound device installed in a burr formed through the skull to perform brain surveillance; And
And a catheter insertion support member for supporting insertion of the catheter into the lesion site according to the monitoring of the ultrasonic device,
Performing brain surveillance through the ultrasound device, performing brain tissue extraction for biopsy, aspiration of blood or moisture, expansion of blood vessels, or a combination thereof through the catheter. The method according to claim 1,
Wherein the brain treatment platform comprises:
And an ultrasonic signal input from the ultrasonic device to analyze catheter insertion support information including path, angle, or combination of the catheter insertion direction and brain state Further comprising a controller for displaying an ultrasound image of the brain. The method of claim 2,
The control device includes:
A communication interface for outputting an ultrasonic output control signal and a steering control signal to the ultrasonic device, receiving the ultrasonic signal from the ultrasonic device, and outputting the ultrasonic signal to the brain condition analyzer;
An ultrasound controller for generating an ultrasound output control signal for generating ultrasound in the ultrasound device and outputting the generated ultrasound output control signal to the ultrasound device;
A steering control unit for generating a steering control signal for steering the probe of the ultrasonic apparatus and outputting the steering control signal to the ultrasonic apparatus;
A brain condition analyzing unit for analyzing ultrasound signals received from the ultrasound device through the communication interface unit and extracting catheter insertion support information including path, angle, or combination thereof to be inserted into the catheter and an ultrasound image for a brain state; And
And a display unit for displaying the extracted catheter insertion support information and ultrasound images of brain states. The method of claim 2,
The ultrasonic device includes:
A chamber coupled to the buckle;
A probe disposed in the chamber for generating ultrasonic waves based on an ultrasonic output control signal received from the control device and radiating ultrasonic waves to brain tissue and receiving the ultrasonic waves;
A steering unit coupled to the probe and performing pan and tilt driving of the probe on the basis of a steering control signal input from the controller; And
And a communication interface for receiving an ultrasonic output control signal and a steering control signal from the control device and outputting the ultrasonic wave output control signal and the steering control signal to the probe and the steering unit and transmitting the ultrasonic signal received by the probe to the control device. Treatment platform. The method of claim 4,
The ultrasonic device includes:
And a handle member attached to or detached from the ultrasonic device,
Wherein the ultrasonic device is attached to a burr formed in the skull after attaching the knob member, and the knob member is detached when the installation of the ultrasonic device is completed. The method of claim 4,
The chamber may comprise:
Wherein a tip of the brain that penetrates through the burr hole and contacts the epidermis of the brain is made of a soft material and the inside is filled with hydrogel to prevent damage or contamination of the brain tissue. The method of claim 4,
The steering unit includes:
Wherein the probe is connected to the probe through a wire and then the probe is panned and tilted by wire driving based on the control of the controller. . The method according to claim 1,
Wherein the catheter insertion support member comprises:
Shaped " C " shaped pin,
Wherein a side of the catheter corresponding to the catheter is made of a flexible material so that an angle of entry of the catheter inserted into the brain tissue can be varied. The method according to claim 1,
Wherein the catheter insertion support member comprises:
Shaped " C " shaped pin,
Wherein the catheter is formed by fixing a slope at one side corresponding to the catheter,
Wherein the catheter is inserted into a specific lesion while maintaining a fixed inclination through a catheter insertion support member having a slope corresponding to an entry angle of the catheter determined according to the ultrasound reception information of the ultrasonic device. Platform. The method according to claim 8 or 9,
Wherein the catheter insertion support member comprises:
And a guide groove is formed on one side of the catheter, the guide groove being engaged with the catheter to support the catheter in a vertical direction. A step of installing an ultrasonic device to install an ultrasonic device on the burr formed by drilling the skull;
Operating the ultrasonic device for operating the ultrasonic device for brain surveillance;
Installing a catheter insertion support member for coupling the catheter insertion support member to the ultrasound device based on the monitoring information of the ultrasound device; And
And a catheter insertion step to assist insertion of the catheter into the lesion site through the catheter insertion support member,
Performing brain surveillance through the ultrasound device, and performing brain tissue extraction for biopsy, aspiration of blood or moisture, expansion of blood vessels, or combinations thereof through the catheter. Way. The method of claim 11,
The method for operating a brain treatment platform,
A controller for generating a control signal including an ultrasonic output control signal for generating an ultrasonic wave of the ultrasonic device, a steering control signal for steering a probe of the ultrasonic device, or a combination thereof and outputting the control signal to the ultrasonic device, step; And
The control device analyzes the ultrasound signal input from the ultrasound device, displays catheter insertion support information including path, angle, or combination of the catheter to be inserted based on the analysis result and an ultrasound image of the brain state The method comprising the steps of: analyzing and displaying a brain;

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