KR20190032370A - 암을 치료하기 위한 복합 요법 - Google Patents

암을 치료하기 위한 복합 요법 Download PDF

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Publication number
KR20190032370A
KR20190032370A KR1020197001728A KR20197001728A KR20190032370A KR 20190032370 A KR20190032370 A KR 20190032370A KR 1020197001728 A KR1020197001728 A KR 1020197001728A KR 20197001728 A KR20197001728 A KR 20197001728A KR 20190032370 A KR20190032370 A KR 20190032370A
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KR
South Korea
Prior art keywords
compound
formula
chemotherapeutic agent
leukemia
inv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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KR1020197001728A
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English (en)
Korean (ko)
Inventor
존 에이치. 부시웰러
아누라다 일렌둘라
Original Assignee
유니버시티 오브 버지니아 페이턴트 파운데이션
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Application filed by 유니버시티 오브 버지니아 페이턴트 파운데이션 filed Critical 유니버시티 오브 버지니아 페이턴트 파운데이션
Publication of KR20190032370A publication Critical patent/KR20190032370A/ko
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020197001728A 2016-07-27 2017-07-27 암을 치료하기 위한 복합 요법 Ceased KR20190032370A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662367263P 2016-07-27 2016-07-27
US62/367,263 2016-07-27
PCT/US2017/044124 WO2018022855A1 (en) 2016-07-27 2017-07-27 Combination therapies for treating cancer

Publications (1)

Publication Number Publication Date
KR20190032370A true KR20190032370A (ko) 2019-03-27

Family

ID=61016782

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197001728A Ceased KR20190032370A (ko) 2016-07-27 2017-07-27 암을 치료하기 위한 복합 요법

Country Status (13)

Country Link
US (1) US11241421B2 (enExample)
EP (1) EP3490557B1 (enExample)
JP (1) JP2019525924A (enExample)
KR (1) KR20190032370A (enExample)
CN (1) CN109475542A (enExample)
AU (1) AU2017302330A1 (enExample)
BR (1) BR112019000049A2 (enExample)
CA (1) CA3028461A1 (enExample)
EA (1) EA201990395A1 (enExample)
IL (1) IL263942A (enExample)
MX (1) MX2019000179A (enExample)
WO (1) WO2018022855A1 (enExample)
ZA (1) ZA201900438B (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019226975A1 (en) * 2018-05-24 2019-11-28 University Of Virginia Patent Foundation Combination therapies for treating cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643935A (en) * 1995-06-07 1997-07-01 The University Of North Carolina At Chapel Hill Method of combatting infectious diseases using dicationic bis-benzimidazoles
US6372719B1 (en) * 1998-03-04 2002-04-16 Jay Cunningham ανβ3 integrin antagonists in combination with chemotherapeutic agents
WO2006104668A2 (en) 2005-03-11 2006-10-05 Temple University - Of The Commonwealth System Of Higher Education Composition and methods for the treatment of proliferative diseases
WO2007008490A2 (en) * 2005-07-06 2007-01-18 Kanisa Pharmaceuticals, Inc. Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer
ES2787599T3 (es) * 2009-05-13 2020-10-16 Univ Virginia Patent Foundation Inhibidores de leucemia inv(16)

Also Published As

Publication number Publication date
US20190343820A1 (en) 2019-11-14
EP3490557B1 (en) 2022-09-07
MX2019000179A (es) 2019-06-20
IL263942A (en) 2019-02-28
BR112019000049A2 (pt) 2019-04-02
US11241421B2 (en) 2022-02-08
AU2017302330A1 (en) 2019-01-17
WO2018022855A1 (en) 2018-02-01
EA201990395A1 (ru) 2019-07-31
EP3490557A4 (en) 2020-04-01
ZA201900438B (en) 2019-10-30
JP2019525924A (ja) 2019-09-12
CN109475542A (zh) 2019-03-15
EP3490557A1 (en) 2019-06-05
CA3028461A1 (en) 2018-02-01

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Patent event date: 20190118

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