KR20180057447A - A scanner with a plural near-infrared ray image sensor And converting method of several two-dimensional biomedical image following time taken with scanner to diabetic wound diagnosis three-dimensional biomedical image following time - Google Patents

Abstract

The present invention provides a scanner with plural near infrared ray image sensors. The scanner is composed of a plurality of lasers (100) and a plurality of near infrared ray image sensors (400). A two-dimensional biomedical image following time by the non-invasive and non-contact of a patient′s foot is obtained. After that, it is converted to a diabetic wound diagnosis three-dimensional biomedical image following time. The three-dimensional biomedical image is output to the screen of an output device (600) separately provided. A disease such as diabetics according to the lesion of a patient can be confirmed and the quality of the life of the patient can be improved by removing noise when acquiring the diabetic wound diagnosis three-dimensional biomedical image.

Description

Technical Field [0001] The present invention relates to a scanner having a plurality of near infrared ray image sensors and a method for converting a two-dimensional biometric image according to a plurality of time taken by the scanner into a three-dimensional biometric image for checking diabetic wounds over time image sensor And converting method of several two-dimensional biomedical image following time taken with scanner to diabetic wound diagnosis three-dimensional biomedical image following time}

The present invention relates to a scanner equipped with a plurality of near infrared ray image sensors and a method for converting a two-dimensional biometric image according to a plurality of time taken by the scanner into three-dimensional biometric images for checking diabetic wounds over time, A plurality of lasers for emitting electromagnetic waves in a near infrared range and a plurality of near infrared ray image sensors for acquiring a plurality of two-dimensional biometric images in a non-invasive and non-contact manner, A 3D image reconstruction algorithm is used to acquire a 3D image of a living body according to the time at which the depth is formed, and a time-dependent diabetes mellitus Dimensional bio-images for identifying wounds and then outputting them to a screen of a separate output device, The present invention relates to a scanner having a plurality of near-infrared image sensors capable of detecting a disease such as diabetes by photographing a lesion site, and a three-dimensional biometric image for confirming diabetic wounds Quot; to "

Korea has already entered the aging society for a long time, and 13.1% of the total population will be over 65 years old in 2015, and the rate will increase at a rapid pace to become an aged society after five years, It is expected.

Particularly, when the ratio of the population over 65 years old to the total population is over 7%, it is called an aging society, more than 14% is an aged society, and when more than 20% is a later aged society or super aged society.

As the population ages 65 or older in the above population is aged socially, a significant proportion of people are at greater risk of exposure to the disease.

Hypertension patients and diabetic patients are steadily increasing due to overeating, lack of exercise and stress due to socio-economic development. In particular, the diabetic patients are more likely to suffer from dietary habits of enjoying foods that contain more meat or fat than vegetables do.

In addition, diabetes is one of the five western diseases associated with colon cancer and breast cancer caused by western type dietary habits, and many complications related to blood circulation such as heart disease, cerebrovascular disease, peripheral vascular disease can be induced , There is a case where a wound occurring in the skin is difficult to cure or progressed to ulceration or necrosis.

Therefore, it is important to treat and manage the diabetic patients after diagnosis because the risk of death due to various complications is high.

However, more than 40% of diabetic patients are elderly people who are socially and economically vulnerable to 60 years of age or older, and the diagnosis rate is only 6 to 7% due to difficulties in diagnosis of diabetes, Do.

In the case of diabetic patients, ulcers or necrosis is much more severe and has a wider range than those without diabetes. Therefore, it is possible to perform treatment only through the cutting operation of the foot or end tissues, but the patient who has undergone the above- The quality of life drops sharply.

Diabetic foot disease, a typical chronic complication of diabetes, occurs in 15% of the total diabetic patients.

The diabetic foot pathologies are based on neurological disorders and blood flow disorders, resulting in various lesions such as solid flesh, deformed feet, ulcers, and necrosis due to trauma or infection, and part of the leg is cut except for trauma More than half of the causes are known and account for about 40% of the causes of hospitalization for diabetics.

In addition, about 3% of the people with diabetic footpieces invented by the present invention have undergone cutting operation, and about 30% of the patients experience recurrence within one year after suffering once, and more than half of the patients who underwent surgery after 4 Within a year, you will have surgery on the other foot.

The diabetic foot disease can be prevented in the case of early diagnosis through blood flow change. However, even in the case of diabetic foot disease that has already progressed, treatment such as marginal resection or improvement of blood flow can be performed in order to promote the treatment, The severity of the disease can be reduced.

That is, prevention of diabetic foot disease is more important than treatment, and prevention of ulcer due to diabetes and its cutting rate can be prevented by about 50% or more.

The cause of the diabetic foot disease is a disorder of the cardiac / vascular blood circulation and management after diagnosis is very important.

In the conventional method, there is no medical equipment or medical technology capable of monitoring the blood circulation indirectly in the clinic and monitoring the degree of healing and necrosis of the wound in order to diagnose a disease caused by the disorder of the deep-seated blood vessel circulation The physiological and functional information of the lesion site can not be obtained, so there is a limit to the diagnosis of the specialist, and there is a limit to the medical service of diagnosis, treatment and management provided to the patient because the progress of the patient can not be predicted.

Therefore, it is necessary to develop a new concept near-infrared imaging device to diagnose a disease caused by disorder of the circulation of the heart / blood vessel.

Conventionally, an optical fiber and a photomultiplier tube (PMT) sensor are used as a near-infrared image sensor.

In the case of the optical fiber, there is a need for a highly skilled technique which can reduce the quality of the image due to the use of the limited attenuation value and the limited optical fiber of the PMT sensor.

As a conventional art, a biosensor and a biosensor system including the biosensor disclosed in Japanese Patent Application Laid-Open No. 10-2016-0106378 include a light source unit for irradiating light to a region of interest of the subject; A collimator for guiding the traveling direction of scattered light emitted from the subject; And a spectroscope that receives scattered light from the collimator and performs spectroscopy, and the collimator is a biosensor including a window formed on one side of the collimator so that light emitted from the light source can pass through the collimator have.

As another prior art, a bio-signal measuring sensor and a manufacturing method thereof of Registration No. 10-1506177 include a printed circuit board; A light receiving chip mounted on an upper surface of the printed circuit board; A light emitting chip mounted on an upper surface of the printed circuit board adjacent to the light receiving chip; And a resin sealing portion sealing the light receiving chip mounted on the upper surface of the printed circuit board and the light emitting chip, wherein the resin sealing portion includes a region between the light receiving chip and the light emitting chip, And a first sealing resin that is impermeable in a light wavelength band of the light emitting chip, excluding a region where the light emitting chip is mounted; Wherein the light emitting chip and the light emitting chip are integrally formed by sealing the second sealing resin having transparency in the light wavelength band of the light emitting chip and formed in the area where the light receiving chip and the light emitting chip are mounted, Measurement sensor "

The conventional invention as described above is for diagnosing diseases that depend on visual inspection because the quality of the image is degraded and the medical staff can not diagnose image-based diabetic wounds, and it is difficult to accurately know the severity and progression of ulcers or skin diseases There was a problem that the appropriate treatment time could be missed.

Therefore, according to the present invention, a scanner having a plurality of near-infrared image sensors and a method of converting a two-dimensional biometric image according to a plurality of time taken by the scanner into a three-dimensional biometric image for confirming a diabetic wound over time, A plurality of laser lasers for emitting electromagnetic waves and a plurality of near infrared ray image sensors for acquiring a plurality of two-dimensional biometric images in a non-invasive and non-contact manner, 3D image reconstruction algorithm is used to acquire 3-D bio-images according to the depth of time, and time-dependent diabetic wounds can be confirmed to intensively check blood flow in 3-dimensional bio images according to the time After converting the image into a 3D bioimage and outputting it to the screen of a separate output device, It is possible to confirm the diseases such as diabetes and the bio-condition such as the blood circulation of the human subcutaneous tissue, the healing of the wound or ulcer, and the degree of necrosis by improving the quality by removing the noise when acquiring the 3D bio- It can be used as an auxiliary device for clinical diagnosis by showing it in real time. It can be used as a diagnostic device for clinical diagnosis, treating, diagnosing and managing the cardiovascular blood circulation disorder such as necrotizing lesions of diabetic patients, And a method for converting a two-dimensional biometric image according to a plurality of time taken by the scanner into three-dimensional biometric images for checking diabetic wounds over time.

The scanner equipped with a plurality of near infrared ray image sensors includes a scanner 100 having a plurality of laser beams 100 and a plurality of near infrared ray image sensors 400, Dimensional bioimage image for confirmation of diabetic wounds according to time, and outputs it to the screen of the output device 600 provided separately.

According to another aspect of the present invention, there is provided a method for converting a two-dimensional biometric image into a three-dimensional biometric image for identifying a diabetic wound over time, the plurality of near- An electromagnetic wave outputting step of irradiating near infrared electromagnetic waves having different wavelengths through a plurality of lasers 100 of a scanner provided with the laser 400; An electromagnetic wave moving step of reflecting and diffusing the electromagnetic wave through a beam splitter (200) and a galvanometer system (300) in a direction of a surface of a lesion of a patient; An electromagnetic wave sensing step of sensing a light amount of an electromagnetic wave reflected on the surface of the patient and sensing a plurality of near infrared ray image sensors 400 and sending a signal to the controller 500; A two-dimensional biometric image acquiring step of acquiring a two-dimensional biometric image according to each time through the signals of the plurality of near-infrared image sensors 400 provided in the scanner; A three-dimensional biometric image acquisition step according to a time when the controller 500 acquires a three-dimensional biometric image according to a time by applying a three-dimensional image reconstruction algorithm to a two-dimensional biometric image according to a plurality of time; A three-dimensional biometric image enhancement step of converting a three-dimensional biometric image according to the time to a three-dimensional biometric image for confirming diabetic wounds over time according to intensification of blood flow; .

The present invention relates to a scanner equipped with a plurality of near infrared ray image sensors and a method for converting a two-dimensional biometric image according to a plurality of time taken by the scanner into a three-dimensional biometric image for checking a diabetic wound over time, A plurality of near infrared rays image sensors, and acquiring a plurality of two-dimensional biometric images in a non-invasive and non-contact manner over a plurality of time periods, Dimensional bioimages for obtaining the time of the depth of the blood vessel and acquiring a 3D bioimage for the time of the depth of the biomedical image, And then outputting the converted data to the screen of a separate output device, it is possible to prevent diseases such as diabetes In addition, when the 3D biopsy image for the diagnosis of diabetic wounds is acquired, noise is removed to improve the quality of the blood, thereby showing the biological condition such as the blood circulation of the human subcutaneous tissue, healing of the wound or ulcer, It can be used as an auxiliary diagnostic device for the diagnosis of diabetic patients and it has a remarkable effect of improving the quality of life of patients by treating, diagnosing and managing the cardiovascular blood circulation disorder such as necrotizing lesions of diabetic patients.

1 is a schematic diagram of a scanner for two-
Fig. 2 is a conceptual diagram of applying stereoscopic in the present invention
FIG. 3 is a conceptual diagram for calculating a formula for applying stereoscopic in the present invention
FIG. 4 is a flowchart illustrating a three-dimensional biometric image conversion sequence for identifying diabetic wounds according to the present invention.

The scanner equipped with a plurality of near infrared ray image sensors includes a scanner 100 having a plurality of laser beams 100 and a plurality of near infrared ray image sensors 400, Dimensional bioimage image for confirmation of diabetic wounds according to time, and outputs it to the screen of the output device 600 provided separately.

In addition, the scanner having the plurality of near-infrared image sensors includes a body 10 having an inner space and an opening formed at one side thereof so that electromagnetic waves can pass therethrough; A plurality of lasers (100) installed inside the body (10) to shoot near-infrared electromagnetic waves; A beam splitter 200 installed in the body 10 for transmitting or reflecting electromagnetic waves of the laser 100; The electromagnetic wave transmitted or reflected by the beam splitter 200 is transmitted through the opening of the body 10 in the direction of the surface of the patient 10 outside the body 10 A galvanometer 300 for scattering while reflecting; A plurality of light sources for detecting a light intensity of an electromagnetic wave passing through a surface of a patient's lesion outside the body 10 through an opening of the body 10, A near infrared ray image sensor 400; Dimensional biometric images are acquired from the signals of the respective near infrared ray image sensors 400 and then the two-dimensional biometric images are taken in accordance with the time, A control unit 500 for converting the three-dimensional image into a three-dimensional image; .

In addition, the plurality of near infrared ray image sensors 400 simultaneously sense a lesion-generated foot and a lesion-free foot of a patient having diabetic foot disease and transmit a signal to the control unit 500, 500) showed the difference between the hemoglobin (Oxy- / Deoxy-) value of the affected foot and the hemoglobin (Oxy- / Deoxy-) value of the uninvolved foot by 3D bioimaging for the diagnosis of diabetic wounds over time And displayed on the screen of the output device 600 as an index.

In addition, the plurality of near infrared ray image sensors 400 continuously detect the lesioned foot and send a signal to the control unit 500. The blood flow control device is worn on the thigh or the calf of the affected foot, The plurality of near infrared ray image sensors 400 photographs the change in hemoglobin and sends a signal to the control unit 500. The control unit 500 determines whether the diabetic wounds And the degree of diabetic foot disease is determined as an index on the screen of the output device 600. The diabetic foot symptom of the diabetic footbath is calculated based on the change of hemoglobin from the three- .

According to another aspect of the present invention, there is provided a method for converting a two-dimensional biometric image into a three-dimensional biometric image for identifying a diabetic wound over time, the plurality of near- An electromagnetic wave outputting step of irradiating near infrared electromagnetic waves having different wavelengths through a plurality of lasers 100 of a scanner provided with the laser 400; An electromagnetic wave moving step of reflecting and diffusing the electromagnetic wave through a beam splitter (200) and a galvanometer system (300) in a direction of a surface of a lesion of a patient; An electromagnetic wave sensing step of sensing a light amount of an electromagnetic wave reflected on the surface of the patient and sensing a plurality of near infrared ray image sensors 400 and sending a signal to the controller 500; A two-dimensional biometric image acquiring step of acquiring a two-dimensional biometric image according to each time through the signals of the plurality of near-infrared image sensors 400 provided in the scanner; A three-dimensional biometric image acquisition step according to a time when the controller 500 acquires a three-dimensional biometric image according to a time by applying a three-dimensional image reconstruction algorithm to a two-dimensional biometric image according to a plurality of time; A three-dimensional biometric image enhancement step of converting a three-dimensional biometric image according to the time to a three-dimensional biometric image for confirming diabetic wounds over time according to intensification of blood flow; .

The present invention will be described in detail with reference to the accompanying drawings.

FIG. 2 is a conceptual diagram for applying stereoscopic in the present invention. FIG. 3 is a conceptual diagram for calculating a formula for applying stereoscopic in the present invention. FIG. 3 is a flowchart of a three-dimensional biometric image conversion for checking a diabetic wound over time.

The present invention relates to a scanner having a plurality of near infrared ray image sensors, a scanner having a plurality of lasers and a plurality of near infrared ray image sensors, After the biometric image is acquired, the biometric image is converted into a three-dimensional biometric image for confirming the diabetic wound according to the time, and is output to the screen of the output device provided separately.

The scanner having the plurality of near infrared ray image sensors includes a body having an inner space and an opening formed at one side thereof so that electromagnetic waves can pass through the body; A plurality of lasers installed in the body, the lasers emitting near-infrared electromagnetic waves; A beam splitter disposed inside the body, the beam splitter transmitting or reflecting the electromagnetic waves of the respective lasers; A galvanometer which is installed inside the body and reflects electromagnetic waves transmitted or reflected by the beam splitter through the opening of the body while reflecting the reflected electromagnetic waves in the direction of the surface of the lesion of the patient outside the body, Wow; A plurality of near infrared ray image sensors installed inside the body for sensing a light intensity of electromagnetic waves passing through a surface of a patient's lesion outside the body through an opening of the body; Dimensional biometric images are acquired from the signals of the respective near infrared ray image sensors, and then converted into three-dimensional biometric images for confirming diabetic wounds with time through two-dimensional biometric images with respect to time ; .

In this case, the 3D bioimage image for confirming the diabetic wound according to the time acquired by the controller is output from a screen of an output device provided separately as an image having a volume, and the 3D bioimage image for identifying the wound according to the time is hemoglobin And it is an improved image to make it easy to check the concentration of

The scanner having the plurality of near infrared ray image sensors is connected to a separate output device through a cable and transmits the 3D biometric image for checking the diabetic wound according to the time of the controller to the output device through the cable, Dimensional biometric image according to time is displayed on the screen of the display unit.

The separately provided output device is a device that is commonly used, or a device having a screen such as a PC.

The body has an inner space formed in a hexahedron shape, and an opening is formed to allow electromagnetic waves to pass through the one side or to sense the outside of the body through the near-infrared image sensor.

At this time, a transparent glass through which the near-infrared electromagnetic wave can pass may be coupled to the opening of the body.

A drive driver is installed to drive the plurality of lasers.

The electromagnetic waves output from the laser use a wavelength of 600 nm or more and 950 nm or less so as to measure the inside of the body through the surface of the patient.

Particularly, when the wavelength of the electromagnetic wave is less than 600 nm or more than 950 nm, it is blocked at the surface of the body and the inside can not be emitted.

The wavelength of the electromagnetic wave of not less than 600 nm and not more than 950 nm used in the present invention is defined as near infrared rays.

On the other hand, the plurality of lasers emit electromagnetic waves having different wavelengths, and each laser is repeatedly turned on and off in a predetermined order according to the control of the controller.

Therefore, the controller can distinguish the images by the wavelengths through the signals sensed through the near-infrared image sensor.

The beam splitter is provided so that electromagnetic waves output from the laser are directed toward the galvanometer system.

Particularly, the beam splitter is installed diagonally to the direction in which the electromagnetic wave is moved, that is, the electromagnetic wave is applied in a direction in which the angle is 45 degrees from one side.

At this time, when the electromagnetic wave touches the surface of the beam splitter, the electromagnetic wave passes through the beam splitter or is reflected at 90 degrees along the path of the electromagnetic wave and the direction of the surface of the beam splitter corresponding to the path of the electromagnetic wave.

Therefore, the number of the beam splitters is set to be equal to or less than the number of the laser beams, so that the paths of the electromagnetic waves output from the plurality of laser beams are directed toward the galvanometer system.

For example, three lasers and two beam splitters are used to shoot electromagnetic waves of different wavelengths, and the wavelengths of the electromagnetic waves of the laser are 830 nm, 785 nm and 650 nm.

The direction of the electromagnetic wave of the laser beam that emits the electromagnetic wave of 650 nm is set so as to be in line with the direction of the galvanometer system. Two beam splitters are installed at an angle of 45 degrees between the laser beam and the galvanometer system.

That is, the electromagnetic wave having the wavelength of 650 nm passes through the two beam splitters and reaches the galvanometer.

A laser is provided to emit an electromagnetic wave of 785 nm in the direction of the first beam splitter at a position spaced apart from the direction of 90 degrees in the tilted direction of the first beam splitter in the direction in which the electromagnetic wave of 650 nm passes.

At this time, the first beam splitter reflects the electromagnetic wave of 785 nm at 90 degrees, and moves in the direction of the galvanometer system in the same way as the path of the electromagnetic wave of 650 nm.

A laser is installed so as to shoot an electromagnetic wave of 830 nm in the direction of the second beam splitter at a position spaced apart from the direction of 90 degrees in the tilted direction of the second beam splitter in the direction in which the 650 nm and 785 nm electromagnetic waves pass simultaneously have.

At this time, the second beam splitter reflects the electromagnetic wave of 785 nm at 90 degrees and moves it in the direction of the galvanometer system in the same way as the path of 650 nm electromagnetic wave and 785 nm electromagnetic wave.

That is, each electromagnetic wave is directed toward the galvanometer system by the splitter.

At this time, the galvanometer system is provided with two or more mirrors rotating in a motorized manner, and it is possible to control the flow of electromagnetic waves that are transmitted through the beam splitter through the two or more mirrors.

At this time, a laser control technique using two or more transmission type mirrors for controlling the flow of electromagnetic waves through the galvanometer system is applied.

The plurality of near infrared ray image sensors are spaced apart from each other by a predetermined distance, and each of the near infrared ray image sensors senses a location where a lesion of a patient having diabetic foot disease occurs at different positions.

At this time, each near-infrared image sensor transmits a signal sensed by the non-invasive and non-contact sensor to the patient, and the controller acquires a two-dimensional biometric image according to a plurality of time intervals through each signal.

Thereafter, the controller converts a plurality of time-based two-dimensional biometric images obtained through the signals sensed at different positions into three-dimensional biometric images according to the depth-formed time through a three-dimensional image reconstruction algorithm.

At this time, a stereoscopic-based three-dimensional shape scanning technique is applied to the 3D image reconstruction algorithm.

를 통해 거리 z를 연산하여 합성할 수 있다.The stereoscopic is to synthesize mesh information of a three-dimensional space representing the skin surface and synthesize the two images into three-dimensional image information as seen by a human being. As shown in FIG. 3,

The distance z can be calculated and synthesized.

In order to confirm intensively the flow of blood in the 3-dimensional biomedical image according to the above-mentioned time, it is necessary to convert (improve) the 3-dimensional biomedical image for confirming the diabetic wound according to the time that the diabetic wound can be confirmed over time, And outputting it to the screen of the output device, it is possible to confirm the disease such as diabetes according to the lesion of the patient.

The mathematical algorithms used to reconstruct the 3-dimensional images according to the time into the 3D bioimages for the diagnosis of diabetic wounds with time include principle component analysis (PCA), independent component analysis (ICA), multiple signal classification .

And the diabetic foot disease is judged through 3-dimensional biomedical image for confirming the diabetic wound according to the time.

The method of judging the diabetic foot disease through the scanner of the present invention may be a method of measuring the difference according to the change of the flow of the foot on which the lesion is formed and the foot on which the lesion is not formed and determining the blood flow control of the thigh or calf There is a method of measuring and determining repeatedly interrupting and opening the blood vessel through the blood flow control device after wearing the device.

At this time, the information determined through the scanner is displayed on the screen of the output device as an index.

The above index is displayed on the screen so that diabetic footprick can not be healed or cured by only the near infrared intensity value of the diabetic patient.

A method for measuring and determining the difference between the lesion-formed foot and the foot without the lesion according to the change of the blood flow will be described in detail.

The plurality of near infrared ray image sensors simultaneously detect a diseased foot of a patient having a diabetic foot disease and a foot without a lesion and transmit a signal to the control unit.

At this time, the control unit calculates the hemoglobin (Oxy- / Deoxy-) value of a lesion in which a lesion has occurred and the hemoglobin (Oxy- / Deoxy-) value of a lesion in which lesion has not occurred And displays the difference on the screen of the output device as an indicator.

A method of measuring blood pressure by repeatedly interrupting and opening a blood vessel through a blood flow control device after wearing a blood flow control device such as a tube on the thigh or calf is described in detail.

The plurality of near infrared ray image sensors continuously detect the lesioned foot and send a signal to the control unit. When the blood flow control device is worn on the thigh or calf of the affected foot, the blood vessel can be blocked or opened.

Then, when the blood vessels that are opened through the blood flow control device are blocked, the veins returning to the heart are blocked, and the arteries supplying the blood flow to the respective tissues are blocked.

At this time, oxyhemoglobin is lowered at the feet where the blood flow is blocked due to the time during which the vein and the artery are blocked, and dioxime hemoglobin is increased, but the total hemoglobin is increased.

That is, when the lesion does not occur, the hemoglobin continuously changes in the portion where the blood flow is blocked and the heat is repeated. On the contrary, when the lesion occurs, the hemoglobin change becomes less or less than the peripheral portion.

The plurality of near infrared ray image sensors capture a change in hemoglobin and send a signal to a control unit. The control unit calculates a hemoglobin change from a three-dimensional bioimage image for confirming diabetic wounds over time, The diabetic foot disease is judged to have occurred and the extent of the diabetic foot disease is indicated on the screen of the output device.

The scanner having the plurality of near infrared ray image sensors according to the present invention can provide a health check-up visit management service for a layer vulnerable to a medical service because the scanner is portable and easy to carry.

A method for converting a two-dimensional biometric image captured through a near-infrared-based two-dimensional biometric imaging scanner into a three-dimensional biometric image for identifying diabetic wounds with time is as follows.

First, an electromagnetic wave output step of scanning an electromagnetic wave through a plurality of lasers of a scanner; An electromagnetic wave moving step of reflecting the electromagnetic wave through a beam splitter and a galvanometer in the direction of the surface of the lesion of the patient and reflecting the same; An electromagnetic wave sensing step of sensing a light amount of an electromagnetic wave reflected on the surface of the patient and sensing a near infrared ray image sensor and sending a signal to the control unit; A two-dimensional biometric image acquiring step of acquiring a two-dimensional biometric image according to each time through signals of a plurality of near-infrared image sensors provided in the scanner; A three-dimensional biometric image acquiring step of acquiring a three-dimensional biometric image according to time by applying a three-dimensional image reconstruction algorithm to the two-dimensional biometric image according to a plurality of time; A three-dimensional biometric image enhancement step of converting a three-dimensional biometric image according to the time to a three-dimensional biometric image for confirming diabetic wounds over time according to intensification of blood flow; .

In order to display the 3D bioimages for scratching according to the time on the screen of a separate output device, a finite element analysis (Finite Element Analysis) and an inverse operation of the reconstructed functional biomedical image are applied.

The three-dimensional finite element analysis is a computer simulation technique for obtaining an approximate value by a finite element method (FEM) and then performing a three-dimensional modeling to obtain a visualized result.

In order to output a three-dimensional biometric image for confirming a wound according to time to the output device, a three-dimensional biometric image according to time should be converted into a three-dimensional biometric image for wound confirmation according to time.

In order to convert the three-dimensional bioimages for time-based wound confirmation into a plurality of images in sequence, one or more images are selected from all the separated images, Conversion.

At this time, the three-dimensional biomedical image for confirming the wound according to the time is an improved image for easily checking the concentration of hemoglobin.

Each separated image includes a signal component and a noise component that can be combined into a three-dimensional image, and the signal-to-noise ratio becomes lower as the separated order becomes closer to the latter part.

The signal-to-noise ratio is a ratio of a signal component to a noise component when a necessary signal and unnecessary noise are mixed.

Wherein the plurality of separated images have a small number of signal components and a smallest noise component in the first image in order, and the signal components are reduced and the noise components are increased in sequence in the backward order, In the order of dividing, the noise becomes more and more important image in the latter half.

The signal-to-noise ratio is divided into an image of a signal component and an image of a noise component according to the signal-to-noise ratio.

For example, an image having a signal component greater than or equal to a noise component is divided into an image of a signal component through the signal-to-noise ratio, and an image having a signal component smaller than a noise component in a signal-to-noise ratio is classified as a noise component image.

Conventional techniques use only processed images after extracting images having a high priority. However, if reconstructed 3-D images are processed by removing images with many noise components placed in the latter half of the sequence, they can not be reconstructed into original 3-D images after the inverse operation.

Therefore, in the present invention, a three-dimensional image is used separately for each image, and functional biological images reconstructed through the separated images can be inversely calculated.

The 3D bioimages for the diagnosis of diabetic wounds are acquired using a Monte Carlo simulation method for 3D bioimages, a time and spatial image analysis algorithm, or a background noise reduction algorithm.

The three-dimensional biomedical image for confirming the diabetic wound is an improved tomographic image for intensively checking the flow of blood. The three-dimensional biomedical image for identifying diabetic wounds is displayed on the screen of the output device The skin condition, the subcutaneous condition, the disease state, and the necrotic lesion.

Particularly, the background noise elimination algorithm is applied to solve a low signal-to-noise ratio (SNR) problem in a biometric image acquisition using an image sensor (CCD / CMOS).

In this case, the signal-to-noise ratio is a ratio of a signal component to a noise component when a necessary signal and unnecessary noise are mixed, and the signal-to-noise ratio becomes a signal component / a noise component.

The larger the ratio of the signal-to-noise ratio (SNR) is, the more surely the defect can be detected.

The 3D bioimages for the diagnosis of diabetic wounds according to the present invention enable a specialist to diagnose diseases more accurately, improve the quality of medical services through accurate diagnosis, promote the domestic medical device market , And further develops medical technology through evidence-based diagnosis in the future.

Accordingly, the present invention provides a scanner having a plurality of near-infrared image sensors, and a method for converting a plurality of time-taken two-dimensional biometric images captured through the scanner into three-dimensional biometric images for checking diabetic wounds over time, A plurality of lasers and a plurality of near infrared ray image sensors, acquiring a plurality of time-based two-dimensional biometric images in a non-invasive and non-contact manner, Dimensional bioimages in accordance with the time at which the depth was formed through the algorithm and to confirm intensively the flow of blood appearing in the 3-dimensional biomedical image according to the time, And then outputting it to the screen of a separate output device, thereby detecting diabetes mellitus It is possible to confirm the diseases and improve the quality by removing the noise when acquiring the 3D bio image for checking the diabetic wounds, thereby realizing the biological condition such as the blood circulation of the human subcutaneous tissue, healing for the wound or ulcer, It can be used as a diagnostic device for clinical diagnosis and it has a remarkable effect of improving the quality of life of patients by treating, diagnosing and managing the cardiovascular blood circulation disorder such as necrotizing lesions of diabetic patients by applying it to the clinic .

10: Body
100: laser
200: beam splitter
300: galvanometer
400: near-infrared image sensor
500:
600: Output device

Claims (5)

A two-dimensional biometric image is acquired over time by non-invasive and non-contact of a patient's foot through a scanner having a plurality of lasers 100 and a plurality of near infrared ray image sensors 400, And outputs the image data to a display device of an output device (600) separately provided with the near infrared ray image sensor [3] The apparatus according to claim 1, wherein the plurality of near infrared ray image sensors include a body having an inner space and an opening formed at one side thereof so that electromagnetic waves can pass through the body; A plurality of lasers (100) installed inside the body (10) to shoot near-infrared electromagnetic waves; A beam splitter 200 installed in the body 10 for transmitting or reflecting electromagnetic waves of the laser 100; The electromagnetic wave transmitted or reflected by the beam splitter 200 is transmitted through the opening of the body 10 in the direction of the surface of the patient 10 outside the body 10 A galvanometer 300 for scattering while reflecting; A plurality of light sources for detecting a light intensity of an electromagnetic wave passing through a surface of a patient's lesion outside the body 10 through an opening of the body 10, A near infrared ray image sensor 400; Dimensional biometric images are acquired from the signals of the respective near infrared ray image sensors 400 and then the two-dimensional biometric images are taken in accordance with the time, A control unit 500 for converting the three-dimensional image into a three-dimensional image; And a plurality of near infrared ray image sensors The method according to claim 1, wherein the plurality of near infrared ray image sensors (400) simultaneously detect a diseased foot of a patient having a diabetic foot disease and a foot without a lesion, and transmits a signal to the control unit The control unit 500 calculates the hemoglobin (Oxy- / Deoxy-) value of the affected foot and the hemoglobin (Oxy- / Deoxy-) of the foot without lesion through the 3D bio- And displays the calculated difference in the form of an index on the screen of the output device (600). The near-infrared image sensor [3] The apparatus according to claim 1, wherein the plurality of near infrared ray image sensors (400) continuously detect the lesioned foot and send a signal to the control unit (500), wear the blood flow control device on the thighs or calves of the affected foot, When the blood vessels are intercepted and opened repeatedly through the blood flow control device, the plurality of near infrared ray image sensors 400 photographs the change in hemoglobin and sends a signal to the control unit 500, After calculating the hemoglobin change from the 3D bioimage image for confirming diabetic wounds, it is determined that the diabetic foot disease has occurred when the change is slow or not compared with the surrounding area, and the degree of diabetic foot disease is displayed on the screen of the output device 600 Which is provided with a plurality of near infrared ray image sensors, An electromagnetic wave outputting step of irradiating near infrared electromagnetic waves having different wavelengths through a plurality of lasers 100 of a scanner provided with a plurality of near infrared ray image sensors 400; An electromagnetic wave moving step of reflecting and diffusing the electromagnetic wave through a beam splitter (200) and a galvanometer system (300) in a direction of a surface of a lesion of a patient; An electromagnetic wave sensing step of sensing a light amount of an electromagnetic wave reflected on the surface of the patient and sensing a plurality of near infrared ray image sensors 400 and sending a signal to the controller 500; A two-dimensional biometric image acquiring step of acquiring a two-dimensional biometric image according to each time through the signals of the plurality of near-infrared image sensors 400 provided in the scanner; A three-dimensional biometric image acquisition step according to a time when the controller 500 acquires a three-dimensional biometric image according to a time by applying a three-dimensional image reconstruction algorithm to a two-dimensional biometric image according to a plurality of time; A three-dimensional biometric image enhancement step of converting a three-dimensional biometric image according to the time to a three-dimensional biometric image for confirming diabetic wounds over time according to intensification of blood flow; Dimensional biometric images taken by a scanner equipped with a plurality of near infrared ray image sensors 400 and converting the two-dimensional biometric images into a three-dimensional biometric image for checking diabetic wounds with time

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