KR20180056902A - Skin whitening and sunscreen composition comprising nano materials and chinese medicine extract - Google Patents

Skin whitening and sunscreen composition comprising nano materials and chinese medicine extract Download PDF

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KR20180056902A
KR20180056902A KR1020160154822A KR20160154822A KR20180056902A KR 20180056902 A KR20180056902 A KR 20180056902A KR 1020160154822 A KR1020160154822 A KR 1020160154822A KR 20160154822 A KR20160154822 A KR 20160154822A KR 20180056902 A KR20180056902 A KR 20180056902A
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extract
skin
whitening
sunscreen composition
nanocrystalline cellulose
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가오 용리앙
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가오 용리앙
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures

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  • Life Sciences & Earth Sciences (AREA)
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Abstract

The present invention provides a skin whitening and sunscreen composition containing a nanomaterial and a Chinese herbal extract, wherein the nanomaterial comprises a nanocrystalline cellulose or nanocrystalline cellulose-fullerene particle mixture, and the Chinese herbal extract comprises a Cordyceps militaris extract, an Artemisia princeps extract, a Lonicera japonica extract, a pearl powder extract, menthol and water. The content of the nanomaterial is 4-7 wt%, and the total content of the Cordyceps militaris extract, the Artemisia princeps extract, the Lonicera japonica extract, the pearl powder extract and the menthol is 3-10 wt%.

Description

나노물질 및 중의약 추출물을 포함하는 피부 미백 및 일광차단 조성물{SKIN WHITENING AND SUNSCREEN COMPOSITION COMPRISING NANO MATERIALS AND CHINESE MEDICINE EXTRACT}TECHNICAL FIELD The present invention relates to a skin whitening and sunscreen composition containing nanomaterials and herbal medicine extracts,

본 발명은 피부-케어 분야에 관한 것이며, 보다 구체적으로 나노결정질 셀룰로스 (NCC) 및 중국 약초 추출물을 함유하는 피부-미백 및 일광차단 조성물에 관한 것이다.The present invention relates to the field of skin-care and more particularly to skin-whitening and sunscreen compositions containing nanocrystalline cellulose (NCC) and Chinese herbal extracts.

피부-미백 및 일광차단은 얼굴 문제를 완화 또는 제거하는데 인기가 높다. 그러나, 대부분의 피부-미백 및 일광차단 제품은 중금속 또는 형광 분말 성분을 포함한다. 예를 들면, 대부분의 피부-미백 및 일광차단 성분은 이산화티타늄 (TiO2)을 포함한다. 공개 번호 CN102076317A의 중국 특허에는 이산화티타늄을 함유하는 화장 제품이 개시되어 있다. 이산화티타늄은 피부-미백 및 일광차단, UV 차단 등에 대한 효과가 우수하나, 이산화티타늄은 자외선광 (UV)의 반사 하에서는 매우 하얀 것처럼 보이지만, 이산화티타늄의 사용이 중지되면 피부 표면에 남아 있는 피부-미백 및 일광차단 성분이 씻겨 없어진 후에는 피부가 본래의 모습으로 되돌아간다. 게다가, 상기 피부-미백 및 일광차단 성분을 장기간 사용할 경우, 피부에 일부 손상이 유발될 것이다. 게다가, 이산화티타늄을 함유하는 피부-미백 및 일광차단 제품은 피부가 특히 자연스럽지 못하게 보이게 하며, 이는 피부-미백 및 일광차단 효과에 영향을 미친다. 환언하면, 이산화티타늄을 대체할 수 있으며, 피부에 손상이 적거나 또는 손상이 전혀 없는 피부-미백 및 일광차단 성분에 대한 수요가 존재한다.Skin-whitening and sun blockers are popular for alleviating or eliminating facial problems. However, most skin-whitening and sunscreen products contain heavy metal or fluorescent powder components. For example, most skin-whitening and sunscreen ingredients include titanium dioxide (TiO 2 ). The Chinese patent of Publication No. CN102076317A discloses a cosmetic product containing titanium dioxide. Titanium dioxide has a good effect on skin-whitening, sunshine and UV shielding, but titanium dioxide appears to be very white under the reflection of ultraviolet light (UV), but when the use of titanium dioxide stops, skin- And after the sunscreen component is washed away, the skin returns to its original appearance. In addition, long-term use of the skin-whitening and sunscreen ingredients will cause some damage to the skin. In addition, skin-whitening and sunscreen products containing titanium dioxide make the skin particularly unpleasant, which affects skin-whitening and sunscreen effects. In other words, there is a need for skin-whitening and sunscreen ingredients that can replace titanium dioxide and have little or no damage to the skin.

더욱이, 나노결정질 셀룰로스는 사람의 노화에 맞서기 위한 고-효율 항산화제이다. 상기 초강력 항산화제 화합물은 사람의 건강을 향상시킬 수 있을 뿐 아니라, 더 많은 노화 방지 제품에 사용될 수 있다.Moreover, nanocrystalline cellulose is a high-efficiency antioxidant to counteract human aging. The super strong antioxidant compound not only can improve human health, but also can be used in more anti-aging products.

본 발명의 목적은 나노결정질 셀룰로스의 항산화 기능 및 자연스러우며, 무해하며, 건강한 전통 중의약의 이로운 측면을 충분히 이용하는 피부-미백 및 일광차단 조성물을 제공하고자 한다.It is an object of the present invention to provide a skin-whitening and daylight-blocking composition that fully utilizes the antioxidant functions of nanocrystalline cellulose and the beneficial aspects of natural, harmless and healthy traditional medicinal herbs.

본 발명의 측면에 의하면, 나노물질 및 중국 약초 추출물을 함유하는 피부-미백 및 일광차단 조성물이 제공되며, 여기서 나노물질은 나노결정질 셀룰로스 또는 나노결정질 셀룰로스-풀러렌 입자 혼합물을 포함하며; 중국 약초 추출물은 동충하초(Cordyceps sinensis) 추출물, 애엽(Folium artemisiae argyi) 추출물, 인동(Honeysuckle) 추출물, 진주 가루(Pearl powder) 추출물, 멘톨 및 물을 포함하며, 여기서 나노물질의 함유량은 4-7 중량%이며, 동충하초(Cordyceps sinensis) 추출물, 애엽(Folium artemisiae argyi) 추출물, 인동(Honeysuckle) 추출물, 진주가루(Pearl powder) 추출물, 멘톨의 총 함유량은 3-10 중량%이다. According to an aspect of the present invention there is provided a skin-whitening and sunscreen composition comprising a nanomaterial and a Chinese herb extract, wherein the nanomaterial comprises a nanocrystalline cellulose or nanocrystalline cellulose-fullerene particle mixture; Chinese herbal extracts include Cordyceps sinensis extract, Folium artemisiae argyi extract, Honeysuckle extract, Pearl powder extract, menthol and water, wherein the content of nanomaterial is 4-7 wt. , And the total content of Cordyceps sinensis extract, Folium artemisiae argyi extract, Honeysuckle extract, Pearl powder extract and menthol is 3-10% by weight.

본 발명의 이로운 효과는 나노물질, 예를 들면 나노결정질 셀룰로스가 한편으로는 피부 산화를 방지하기에 이로우며, 다른 한편으로는 나노물질의 비교적 작은 입자 크기로 인하여 피부에 의한 흡수에 이롭다는 점이다.The beneficial effect of the present invention is that nanomaterials, such as nanocrystalline cellulose, on the one hand are beneficial for preventing skin oxidation and on the other hand are beneficial for absorption by the skin due to the relatively small particle size of the nanomaterials .

추가로, 피부-미백 및 일광차단을 위하여 전통 중의약(traditional Chinese medicine)을 사용하는 것은 영양 성분에 의하여 깊은 피부층으로의 침투에 기여하며, 추가로 수분 보유, 피부 습윤, 피부-미백 및 일광차단, 소반점 제거, 주름 방지, 내염증성, 유해 물질 배출, 여드름 제거 등의 기능을 갖는다. 게다가, 중국 약초 성분은 피부가 보다 자연스럽게 보이도록 하는 피부-미백 및 일광차단 효과를 가지며, 장기간 사용후 피부 건강에 이롭다.In addition, the use of traditional Chinese medicine for skin-whitening and sunscreen interventions contributes to penetration into the deep layers of skin by nutritional ingredients, and additionally contributes to moisture retention, skin moisturization, skin-whitening and sun- Anti-wrinkle, anti-inflammatory, discharge of harmful substances, and removal of acne. In addition, Chinese herbal ingredients have skin-whitening and sunscreen effects that make the skin appear more natural, and are beneficial for long-term skin health.

본 발명의 측면에 의하면, 나노물질 및 중국 약초 추출물을 함유하는 피부-미백 및 일광차단 조성물이 제공되며, 여기서 나노물질은 나노결정질 셀룰로스 또는 나노결정질 셀룰로스-풀러렌 입자 혼합물을 포함하며; 중국 약초 추출물은 동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물, 멘톨 및 물을 포함하며, 여기서 나노물질의 함유량은 4-7 중량%이며, 동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물 및 멘톨의 총 함유량은 3-10 중량%이다.According to an aspect of the present invention there is provided a skin-whitening and sunscreen composition comprising a nanomaterial and a Chinese herb extract, wherein the nanomaterial comprises a nanocrystalline cellulose or nanocrystalline cellulose-fullerene particle mixture; The herbal extracts of Chinese herbs include Chinese herbal medicine extracts, Chinese herbal medicine extracts, Chinese herbal medicine extracts, pearl powder extracts, menthol and water, wherein the content of nanomaterials is 4-7% The total content of menthol is 3-10 wt%.

게다가, 나노결정질 셀룰로스 (NCC)는 사람의 노화에 대하여 싸우기 위한 고-효율 항산화제이다. 상기 초-강력 항산화제 화합물은 사람의 건강을 향상시킬 수 있을 뿐 아니라, 더 많은 노화 방지 제품에 사용될 수 있다. 게다가, 나노결정질 셀룰로스는 더 우수한 항-UV 효과를 가지며, 장기간 사용후 피부에 UV 유해를 제거하는데 기여한다.In addition, nanocrystalline cellulose (NCC) is a high-efficiency antioxidant for combating human aging. The super-strong antioxidant compound not only can improve human health, but can also be used in more anti-aging products. In addition, nanocrystalline cellulose has a better anti-UV effect and contributes to the removal of UV hazards to the skin after prolonged use.

본 발명은 나노결정질 셀룰로스를 단독으로 포함할 수 있으며, 또한 NCC는 풀러렌 입자와 배합되어 NCC-풀러렌 입자 혼합물을 형성할 수 있으며, 여기서 풀러렌의 첨가는 나노결정질 셀룰로스의 효과를 더 우수하게 촉진시킨다. 상기 혼합물은 또한 버키 볼(Bucky ball)로 불리울 수 있으며, 사람 체내에서 유해한 자유 라디칼을 흡수 및 중화시킬 수 있는 "나노 진공 청소기"로 간주될 수 있으며, 그리하여 피부 개선 및 피부 유해 완화 효과를 달성할 수 있다.The present invention can include the nanocrystalline cellulose alone and the NCC can also be combined with the fullerene particles to form an NCC-fullerene particle mixture wherein the addition of fullerene facilitates the effect of the nanocrystalline cellulose. The mixture may also be referred to as a bucky ball and can be regarded as a "nano vacuum cleaner" which can absorb and neutralize harmful free radicals in the human body, thereby achieving skin improvement and skin- can do.

NCC-풀러렌 입자 혼합물은 각종 방법을 사용하여 형성될 수 있으며, 본 발명에서 이미 공지되어 있거나 또는 미래에 개발될 임의의 기술을 채택하여 혼합물을 형성할 수 있다. 혼합물의 형성 방법은 본 발명의 논의 주제는 아니므로 더 이상 기재하지 않을 것이다.The NCC-fullerene particle mixture can be formed using various methods, and any technique that is already known in the present invention or which will be developed in the future can be employed to form a mixture. The method of forming the mixture is not a subject of discussion of the present invention and will not be described any further.

본 발명의 실시양태에 의하면, 중국 약초 추출물은 동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물을 포함하며, 여기서 이들 추출물의 총 함유량은 총 중량의 3-10 중량%에 해당한다.According to an embodiment of the present invention, the Chinese herb extract comprises Cordyceps sinensis extract, Leaf extract, Rhododendron extract, Pearl powder extract, wherein the total content of these extracts is 3-10% by weight of the total weight.

본 발명의 제1의 내지 제9의 실시양태에 의하면, 나노결정질 셀룰로스-풀러렌 입자 혼합물의 함유량은 각각 1 중량%-9 중량% 범위내이며, 각각의 실시양태에서의 나노결정질 셀룰로스-풀러렌 입자 혼합물의 함유량은 1 중량%씩 점진적으로 증가된다. 게다가, 제1의 내지 제9의 실시양태에서, 동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물 및 멘톨의 총 함유량은 3 중량%이며, 나노결정질 셀룰로스의 입자 크기는 70 ㎚ 및 80 ㎚ 사이의 범위로부터 선택된다.According to the first through ninth embodiments of the present invention, the content of the nanocrystalline cellulose-fullerene particle mixture is each in the range of 1 wt% to 9 wt%, and the content of the nanocrystalline cellulose-fullerene particle mixture in each embodiment Is gradually increased by 1 weight%. In addition, in the first to ninth embodiments, the total content of the Cordyceps sinensis extract, the lysolecule extract, the rhizome extract, the pearl powder extract and the menthol is 3% by weight, and the particle size of the nanocrystalline cellulose is between 70 nm and 80 nm .

코튼(cotton), 헴프(hemp) 및 목재 펄프 보드에 함유된 식물 섬유의 산 가수분해에 의하여 얻어지는 나노결정질 셀룰로스는 150 ㎚-300 ㎚의 길이, 30 ㎚-100 ㎚의 직경 및 160-180의 중합도를 갖는 나노입자이며, 본 발명의 실시양태에서, 이는 200 ㎚의 길이 및 70-80 ㎚의 직경을 갖는 입자이다. 이러한 실시예는 한편으로는 비교적 더 우수한 효과를 가지며, 다른 한편으로는 비용을 효과적으로 조절할 수 있다.The nanocrystalline cellulose obtained by acid hydrolysis of vegetable fibers contained in cotton, hemp and wood pulp boards has a length of 150 nm to 300 nm, a diameter of 30 nm to 100 nm and a degree of polymerization of 160 to 180 In an embodiment of the present invention, it is a particle having a length of 200 nm and a diameter of 70-80 nm. This embodiment has relatively good effects on the one hand and can effectively control the cost on the other hand.

하기 표 1은 실시양태 1 내지 9에서 상이한 파장을 갖는 광에 대한 흡광도를 비교한 표를 제시한다. 용액의 흡광도는 자외선 및 가시광선 분광광도계 (모델 번호: UV-2450)를 사용하여 측정한다. 흡광 셀의 세부사항: 양면 연마된 석영 흡광 셀 (1 ㎝); 환경 조건: 28℃의 온도; 파장 범위: 280 ㎚-380 ㎚.Table 1 below provides a table comparing the absorbances for light having different wavelengths in Embodiments 1 to 9. The absorbance of the solution is measured using an ultraviolet and visible light spectrophotometer (Model: UV-2450). Details of the light absorbing cell: a double-side polished quartz absorbing cell (1 cm); Environmental conditions: a temperature of 28 캜; Wavelength range: 280 nm-380 nm.

파장wavelength 280 ㎚280 nm 300 ㎚300 nm 320 ㎚320 nm 340 ㎚340 nm 360 ㎚360 nm 380 ㎚380 nm 실시양태 1Embodiment 1 1.181.18 1.261.26 1.221.22 1.241.24 1.031.03 1.271.27 실시양태 2Embodiment 2 1.791.79 1.611.61 1.751.75 1.961.96 1.641.64 1.891.89 실시양태 3Embodiment 3 2.112.11 2.042.04 2.002.00 2.092.09 2.402.40 2.142.14 실시양태 4Embodiment 4 3.673.67 4.194.19 3.613.61 3.703.70 4.274.27 3.763.76 실시양태 5Embodiment 5 3.943.94 3.753.75 4.624.62 3.783.78 4.524.52 4.204.20 실시양태 6Embodiment 6 4.404.40 4.084.08 4.544.54 4.554.55 4.344.34 4.114.11 실시양태 7Embodiment 7 4.014.01 4.174.17 4.524.52 4.434.43 4.644.64 4.534.53 실시양태 8Embodiment 8 4.604.60 4.164.16 4.064.06 3.913.91 3.783.78 4.604.60 실시양태 9Embodiment 9 3.553.55 3.733.73 3.853.85 3.883.88 3.783.78 3.253.25

표 1로부터, 실시양태 1의 경우에서, 즉 나노결정질 셀룰로스-풀러렌 입자 혼합물의 함유량이 1 중량인 경우 280 ㎚의 파장을 갖는 광에 대한 흡광도는 1.18이며, 300 ㎚의 파장을 갖는 광에 대한 흡광도는 1.26이며, 320 ㎚의 파장을 갖는 광에 대한 흡광도는 1.22이며, 340 ㎚의 파장을 갖는 광에 대한 흡광도는 1.24이며, 360 ㎚의 파장을 갖는 광에 대한 흡광도는 1.03이며, 380 ㎚의 파장을 갖는 광에 대한 흡광도는 1.27이라는 것을 알 수 있다. 이러한 수치는 모두 비교적 더 낮은 수준에 있다.It can be seen from Table 1 that in the case of Embodiment 1, that is, when the content of the mixture of nanocrystalline cellulose-fullerene particles is 1 weight, the absorbance for light having a wavelength of 280 nm is 1.18 and the absorbance for light having a wavelength of 300 nm Is 1.26, the absorbance for light having a wavelength of 320 nm is 1.22, the absorbance for light having a wavelength of 340 nm is 1.24, the absorbance for light having a wavelength of 360 nm is 1.03, It is found that the absorbance with respect to light having a wavelength of 1.27 is 1.27. All of these figures are at a relatively lower level.

실시양태 2 및 3의 경우, 흡광도의 특정 증가가 존재하지만, 증가되는 범위는 매우 작으므로 유의한 흡광 정도는 야기되지 않는다.In the case of Embodiments 2 and 3, although there is a specific increase in absorbance, the range of increase is very small, so no significant degree of extinction is caused.

실시양태 4-9 각각의 경우, 흡광도는 유의하게 증가되며, 주로 흡광 정도는 4 이상에 도달할 수 있으며, 이는 UV 광에 의하여 야기되는 피부 유해를 감소시키는데 명백하게 기여한다.In each of the embodiments 4-9, the absorbance is significantly increased, and the degree of extinction can reach up to 4 or more, which clearly contributes to reducing skin harm caused by UV light.

게다가, 각각의 실시양태 8 및 9에서의 흡광도는 또한 4 이상에 도달할 수 있으나, 한편으로는 실시양태 9 및 9의 효과는 실시양태 4-7에 비하여 유의한 개선을 갖지 않으며, 심지어 약화되며, 다른 한편으로는 실시양태 8 및 9는 더 많은 양의 나노결정질 셀룰로스의 첨가를 필요로 하므로 경제적 이점에서 바람직하지 않다.In addition, the absorbance in each of Embodiments 8 and 9 may also reach 4 or more, while on the other hand the effects of Embodiments 9 and 9 do not have significant improvement compared to Embodiments 4-7 and are even weakened On the other hand, Embodiments 8 and 9 are undesirable for economic reasons because they require the addition of higher amounts of nanocrystalline cellulose.

본 발명에서 선택된 바와 같이 70-80 ㎚의 입자 크기를 갖는 나노결정질 셀룰로스는 성능 및 비용 사이의 더 우수한 절충에 도달할 수 있어서 큰 성능을 갖는 제품을 사용자에게 쉽게 제공할 수 있다.As selected in the present invention, nanocrystalline cellulose having a particle size of 70-80 nm can reach a better trade-off between performance and cost, and can easily provide a product with a large performance to a user.

본 발명에서, 동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물, 멘톨 등의 중국 약초 추출물이 하기에 기재되어 있다.In the present invention, Chinese herbal extracts such as Cordyceps sinensis extract, lobster extract, Rhodiola extract, Pearl powder extract and menthol are described below.

동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물은 자연히 미백 효과를 가지며, 이들은 중국 약초 추출물이며, 천연 미백 효과를 가지므로 인체에 유해하지 않으며, 형광 효과를 생성하지 않는다. 게다가, 본 발명의 나노결정질 셀룰로스-풀러렌 입자 혼합물과 조합하여 사용시 전술한 중국 약초 추출물은 피부와의 접촉 면적이 더 커서 피부에 의한 이들 영양 성분의 흡수를 촉진한다.Cordyceps extracts, ladybug extracts, rhizome extracts, and pearl powder extracts have natural whitening effects. They are Chinese herb extracts and have a natural whitening effect, so they are not harmful to the human body and do not produce a fluorescent effect. In addition, when used in combination with the nanocrystalline cellulose-fullerene particle mixture of the present invention, the herbal extract of Chinese herb has a greater contact area with the skin, thereby promoting the absorption of these nutrients by the skin.

멘톨은 민트향 및 청량감 및 상쾌한 효과를 가지며, 사용자가 기분 좋은 마음을 유지하는데 이로우며, 쾌적한 정도를 개선시킨다Menthol has a mint flavor and refreshing sensation and refreshing effect, and it is beneficial for the user to maintain a pleasant mind and improve the comfort level

본 발명의 바람직한 실시양태에 의하면, 동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물 및 멘톨의 중량비는 1-2.5:2-3.5:2.5-4.5:2-4:1-2이다.According to a preferred embodiment of the present invention, the weight ratio of Cordyceps sinensis extract, Leaf extract, Rhizome extract, Pearl powder extract and menthol is 1-2.5: 2-3.5: 2.5-4.5: 2-4: 1-2.

추가로, 생성된 조성물이 긴 작용 수명을 가질 수 있으며, 안정하며, 좋은 촉감을 갖는 것을 보장하기 위하여, 본 발명의 바람직한 실시양태에 의한 피부-미백 및 일광차단 조성물은 하기 성분: 글리세릴 모노스테아레이트, 바셀린, 프로필렌 글리콜, 크산탄 껌, 알로에 겔, 글리세린, 스판(Span), 트윈(Tween) 및 메틸파라벤을 추가로 포함하며, 전술한 성분의 총 함유량은 4 중량%-10 중량%이다.Additionally, in order to ensure that the resulting composition can have a long working life, is stable, and has good tactile properties, the skin-whitening and sunscreen composition according to a preferred embodiment of the present invention comprises the following ingredients: glyceryl monostearate The total content of the above-mentioned components is 4 wt% to 10 wt%, and the total content of the above components is 4 wt% to 10 wt%.

글리세릴 모노스테아레이트는 유화제로서 식품 및 화장 제품에 일반적으로 사용되며; 바셀린은 피부 표면 상의 보호막 형성에 기여하여 수분 손실을 방지하며; 프로필렌 글리콜은 형성된 화합물이 너무 빠르게 수분을 손실하는 것을 방지하여 저장 시간을 연장시키기 위한 얼굴 마스크 또는 젖은 종이 냅킨에서의 보습제로서 일반적으로 사용되며; 크산탄 껌은 조성물의 두께를 개선시키며, 유화계의 안정성을 개선시키며; 알로에 겔은 수분 보유, 일광차단, 냄새 차단, 피부 연화, 염증 약화 및 가려움 완화, 통증 완화, 여드름 및 주근깨 방지, 색소 스폿 완화 등의 기능을 갖는 화장품의 피부 관리 제품에 주로 사용되며; 글리세린은 수분 보유 및 피부가 건조해지는 것을 방지하는 효과를 가지며, 스판은 기타 성분의 용해를 촉진시키기 위한 분산제로서 주로 사용되며; 트윈은 첨가되지 않거나 또는 특정한 바람직하지 않은 냄새를 지녀서 소량으로 첨가되며; 메틸파라벤은 박테리아에 대한 비교적 강한 억제 효과를 가지며, 본 발명의 조성물이 더 길게 작용하도록 하며 안정한 품질을 갖는 것을 보장하기에 이롭다.Glyceryl monostearate is commonly used in food and cosmetic products as an emulsifier; Vaseline contributes to the formation of a protective film on the surface of the skin to prevent water loss; Propylene glycol is commonly used as a moisturizer in facial masks or wet paper napkins to prevent the formed compounds from losing too much moisture and to prolong storage times; Xanthan gum improves the thickness of the composition and improves the stability of the emulsion system; Aloe gel is mainly used in skin care products of cosmetics having functions such as moisture retention, sunshine blocking, odor blocking, skin softening, inflammation weakening and itching relief, pain relief, acne and freckle prevention, pigment spot relaxation; Glycerin has the effect of retaining moisture and preventing the skin from drying out, and span is mainly used as a dispersant for promoting dissolution of other ingredients; The tween is not added or has a particular undesirable odor and is added in minor amounts; Methylparaben has a relatively strong inhibitory effect on bacteria and is advantageous to ensure that the composition of the present invention works longer and has a stable quality.

본 발명의 바람직한 실시양태에 의하면, 글리세릴 모노스테아레이트, 바셀린, 프로필렌 글리콜, 크산탄 껌, 알로에 겔, 글리세린, 스판, 트윈 및 메틸파라벤의 중량비는 글리세릴 모노스테아레이트: 0-1.6; 바셀린: 4-6.5; 프로필렌 글리콜: 0-2; 크산탄 껌: 0-3.5; 알로에 겔: 1.5-4.5; 글리세린: 1-2; 스판: 2.5-5.5; 트윈: 0-1; 및 메틸파라벤: 1.5-3이다.According to a preferred embodiment of the present invention, the weight ratio of glyceryl monostearate, vaseline, propylene glycol, xanthan gum, aloe gel, glycerin, span, tween and methyl paraben is in the range of from 0 to 1.6; Vaseline: 4-6.5; Propylene glycol: 0-2; Xanthan gum: 0-3.5; Aloe gel: 1.5-4.5; Glycerin: 1-2; Span: 2.5-5.5; Twin: 0-1; And methyl paraben: 1.5-3.

제조 방법Manufacturing method

우선, 하기 4종의 군의 물질을 생성한다:First, the following four groups of materials are produced:

A군: 글리세릴 모노스테아레이트, 바셀린, 스판 및 트윈;Group A: glyceryl monostearate, petrolatum, span and tween;

B군: 프로필렌 글리콜, 글리세린 및 나노결정질 셀룰로스-풀러렌 입자 혼합물;Group B: propylene glycol, glycerin and nanocrystalline cellulose-fullerene particle mixture;

C군: 동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물 및 멘톨; 및Group C: Cordyceps melliflora extract, Leaf extract, Rhizome extract, Pearl powder extract and menthol; And

D군: 물, 크산탄 껌, 알로에 겔 및 메틸파라벤;Group D: water, xanthan gum, aloe gel and methyl paraben;

A군의 물질을 우선 50℃로 가열한 후, 고속 균질화 믹서에 넣는다. 그 후, B군의 물질 및 C군의 물질을 A군의 물질에 분당 2,000 회전 (rpm)의 교반 속도 하에서 서서히 첨가하고, A군, B군 및 C군의 물질이 균일하게 혼합된 후 D군의 물질을 첨가하고, 그 후 30 분 동안 연속적으로 동일한 교반 속도 하에서 교반한다. 모든 물질을 믹서로부터 꺼내고, 처리를 위하여 20 ㎫ 고압 균질화기에 넣어서 본 발명의 조성물을 얻는다. 그 후, 조성물을 80℃의 일정한 온도에서 2 시간 동안 살균시키고, 실온으로 자연 냉각시켜 일광차단 크림을 얻는다.The material of group A is first heated to 50 DEG C and then placed in a high-speed homogenization mixer. Subsequently, the substance of Group B and the substance of Group C were gradually added to the substance of Group A at a stirring rate of 2,000 revolutions per minute (rpm), and after the substances of Group A, B and C were uniformly mixed, Lt; / RTI > is added, and then stirred for 30 minutes at the same stirring rate continuously. All materials are removed from the mixer and placed in a 20 MPa high pressure homogenizer for processing to obtain the composition of the present invention. The composition is then sterilized at a constant temperature of 80 DEG C for 2 hours and naturally cooled to room temperature to obtain a sunscreen cream.

당업계의 기술자는 본 발명에 의하여 개시된 조성물을 얻기 위하여 상기 개시된 본 발명의 비 및 함유량에 기초하여 상기 기재된 각각의 성분의 중량을 얻을 수 있는 것으로 이해할 수 있다.It will be understood by those skilled in the art that the weight of each component described above can be obtained based on the ratio and content of the present invention disclosed above to obtain the composition disclosed by the present invention.

본 발명의 조성물은 320-380 ㎚의 UVA 영역 및 280-320 ㎚의 UVB 영역에서의 자외선 조사를 방지할 수 있으며, 그의 일광 차단 지수 (SPF) 값이 15보다 커서 인체의 피부를 보호하는 작용을 한다. 상기 일광차단 크림은 안전하며, 인체에 무해하며, 높은 일광차단 기능을 가지며, 모든 사람에게 적용 가능하다.The composition of the present invention is capable of preventing ultraviolet ray irradiation in the UVA region of 320-380 nm and the UVB region of 280-320 nm and has a sunscreening index (SPF) value of 15 or more to protect the human skin do. The sunscreen cream is safe, harmless to the human body, has a high sunlight shielding function, and is applicable to all persons.

Claims (5)

나노물질 및 중국 약초 추출물을 함유하며, 여기서
나노물질이 나노결정질 셀룰로스 또는 나노결정질 셀룰로스-풀러렌 입자 혼합물을 포함하며;
중국 약초 추출물이 동충하초(Cordyceps sinensis) 추출물, 애엽(Folium artemisiae argyi) 추출물, 인동(Honeysuckle) 추출물, 진주 가루(Pearl powder) 추출물, 멘톨 및 물을 포함하며, 여기서
나노물질의 함유량이 4-7 중량%이며,
동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물 및 멘톨의 총 함유량이 3-10 중량%인 피부-미백 및 일광차단 조성물.
Nanomaterials and Chinese herbal extracts, wherein
Wherein the nanomaterial comprises a nanocrystalline cellulose or nanocrystalline cellulose-fullerene particle mixture;
Wherein the Chinese herb extract comprises Cordyceps sinensis extract, Folium artemisiae argyi extract, Honeysuckle extract, Pearl powder extract, menthol and water, wherein
The content of the nanomaterial is 4-7% by weight,
A skin-whitening and sunscreen composition, wherein the total content of Cordyceps sinensis extract, lobster extract, Rhodiola extract, Pearl powder extract and menthol is 3-10 wt%.
제1항에 있어서, 동충하초 추출물, 애엽 추출물, 인동 추출물, 진주 가루 추출물 및 멘톨의 중량비가 1-2.5:2-3.5:2.5-4.5:2-4:1-2인 피부-미백 및 일광차단 조성물.The skin-whitening and sunscreen composition according to claim 1, wherein the weight ratio of Cordyceps sinensis extract, Rhodiola extract, Rhodophyta extract, Pearl powder extract and menthol is 1-2.5: 2-3.5: 2.5-4.5: 2-4: 1-2 . 제1항에 있어서, 나노결정질 셀룰로스의 입자 크기가 70-80 ㎚인 피부-미백 및 일광차단 조성물.The skin-whitening and sunscreen composition of claim 1, wherein the particle size of the nanocrystalline cellulose is 70-80 nm. 제1항에 있어서, 피부-미백 및 일광차단 조성물이 글리세릴 모노스테아레이트, 바셀린, 프로필렌 글리콜, 크산탄 껌, 알로에 겔, 글리세린, 스판(span), 트윈(tween) 및 메틸파라벤을 더 포함하며, 이들 성분의 총 함유량이 4 중량%-10 중량%인 피부-미백 및 일광차단 조성물.The composition of claim 1, wherein the skin-whitening and sunscreen composition further comprises glyceryl monostearate, vaseline, propylene glycol, xanthan gum, aloe gel, glycerin, span, tween, , And the total content of these components is 4 wt% to 10 wt%. 제4항에 있어서, 글리세릴 모노스테아레이트, 바셀린, 프로필렌 글리콜, 크산탄 껌, 알로에 겔, 글리세린, 스판, 트윈 및 메틸파라벤의 중량비가
글리세릴 모노스테아레이트: 0-1.6;
바셀린: 4-6.5;
프로필렌 글리콜: 0-2;
크산탄 껌: 0-3.5;
알로에 겔: 1.5-4.5;
글리세린: 1-2;
스판: 2.5-5.5;
트윈: 0-1; 및
메틸파라벤: 1.5-3인 피부-미백 및 일광차단 조성물.
The composition according to claim 4, wherein the weight ratio of glyceryl monostearate, vaseline, propylene glycol, xanthan gum, aloe gel, glycerin, span,
Glyceryl monostearate: 0-1.6;
Vaseline: 4-6.5;
Propylene glycol: 0-2;
Xanthan gum: 0-3.5;
Aloe gel: 1.5-4.5;
Glycerin: 1-2;
Span: 2.5-5.5;
Twin: 0-1; And
Methylparaben: 1.5-3. A skin-whitening and sunscreen composition.
KR1020160154822A 2016-11-21 2016-11-21 Skin whitening and sunscreen composition comprising nano materials and chinese medicine extract KR20180056902A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108685805A (en) * 2018-08-16 2018-10-23 南阳艾研健康科技有限公司 A kind of skin maintenance Chinese mugwort carbon face mask of traditional Chinese medicine and the preparation method and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108685805A (en) * 2018-08-16 2018-10-23 南阳艾研健康科技有限公司 A kind of skin maintenance Chinese mugwort carbon face mask of traditional Chinese medicine and the preparation method and application thereof
CN108685805B (en) * 2018-08-16 2021-06-04 南阳艾研健康科技有限公司 Beauty-maintaining and beauty-maintaining Chinese mugwort carbon traditional Chinese medicine mask and preparation method and application thereof

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