KR20180030494A - Dressing Hemostatic Pad And The Method Of Manufacturing The Same - Google Patents

Abstract

The present invention relates to a dressing hemostatic pad in which an alginate nonwoven fabric having excellent hydrophilicity, hemostasis effects, and biocompatibility, a polyurethane foam having excellent absorbing capacity, and a flexible adhesive band capable of being attached to skin are sequentially laminated. A contact section of the polyurethane foam and the adhesive band is located inside of the contact surface of the adhesive band, and the alginate nonwoven fabric is smaller than the area of the grounded polyurethane foam (120). A constituent fiber of the alginate nonwoven fabric is a calcium alginate fiber obtained by dissolving sodium alginate in distilled water and performing wet-spinning through a coagulating bath using calcium chloride. The thickness of the polyurethane foam (120) is greater than the thickness of the alginate nonwoven fabric. The nonwoven fabric is folded and used in multiple sheets, and one sheet of the nonwoven fabric has a thickness of 0.3-5 cm. The alginate nonwoven fabric and the polyurethane foam, for first 24 hours, have a volumetric expansion rate of 180.2-190.5%, an absorption amount of 1.61-1.74 g/cm^2 per unit area, and a water retention amount of 1.08-1.32 g/cm^2 per unit area. The flexible adhesive band induces a volume expansion direction of the polyurethane foam with a porous structure, which has a great ability to absorb blood and exudation from a wound, toward a wound so as to press the wound directly, thereby inducing angiopressure.

Description

≪ Desc / Clms Page number 1 > Dressing Hemostatic Pad and Method of Manufacturing the Same

The present invention relates to a dressing hemostatic pad used as a wound dressing and a method for manufacturing the dressing hemostatic pad. More particularly, the present invention relates to a dressing hemostatic pad comprising a foam absorbing exudate and alginate .

Skin is a body organ that protects the human body from external stimuli, prevents moisture loss, and controls important body functions such as body temperature control and prevention of bacterial invasion. If skin loses its function due to various traumas, Side effects and bacterial infections from the outside, which makes it difficult to treat the affected part, or causes secondary side effects such as secondary dysfunction. In severe cases, it affects life extension. Therefore, in order to accelerate the treatment of wounds and to minimize secondary side effects, it is essential to treat wounds using appropriate dressings.

The dressing used for the wound of the skin used the bandage using the cotton material having excellent water absorption ability at the beginning, but the dressing of the cotton material did not absorb all of the wound discharge generated from the skin wound, and the wound which was not absorbed dried, So that it is not easy to exchange, and there is a problem that it involves new tissue damage and pain.

In addition, the general transparent film dressing material has a characteristic only for blocking the infection with the outside, but there is a limitation in the use when there is exudation or bleeding because there is no absorption power. In recent years, wound healing is more efficient in wet environment than in dry environment, so research on wet wound dressings is the main focus. Therefore, there is a demand for a dressing pad capable of absorbing the exudate from the wound surface and having a biocompatible property, a material capable of doubling the absorbing ability, and a hemostatic effect by applying pressure to the wound.

Korean Patent Laid-open Publication No. 10-2014-0005322 describes a film having an alginate film. Korean Patent Laid-open Publication No. 10-2014-0100245 discloses a polymer composition having a porous structure excellent in absorbency and a polymer composition having a swelling degree, And an elastic wound dressing having improved mechanical properties such as strength and the like.

Disclosure of Invention Technical Problem [8] The present invention has been made in order to solve the above-mentioned problems, and it is an object of the present invention to provide a foam for absorbing exudates and an alginate nonwoven fabric for helping a hemostatic action and recovery of wounds.

Further, the present invention aims at hemostasis by compressing a wound area by expansion of a foam having excellent absorption ability.

Another object of the present invention is to provide an adhesive band excellent in stretchability capable of supporting a change in shape of a foam due to absorption.

It is another object of the present invention to provide a method for bonding an adhesive band and an alginate nonwoven fabric by using the adhesive properties of a polyurethane foam.

To achieve these and other advantages and in accordance with the purpose of the present invention, as embodied and broadly described herein, there is provided a dressing bleeding pad comprising: an alginate nonwoven fabric having excellent hydrophilicity, hemostatic effect and biocompatibility; Wherein a polyurethane foam having excellent absorption ability and a stretchable adhesive band capable of being adhered to the skin are stacked in this order, wherein a contact portion between the polyurethane foam and the adhesive band is located inside the contact surface of the adhesive band, and the alginate non- Wherein the constituent fibers of the alginate nonwoven fabric are calcium alginate fibers obtained by dissolving sodium alginate in distilled water and then wet-spinning through a coagulating bath using calcium chloride, and the poly The thickness of the urethane foam 120 is larger than the thickness of the alginate nonwoven fabric, and the thickness of one of the alginate nonwoven fabric is 0.3 cm to 5 cm. The alginate nonwoven fabric and the polyurethane foam have a volume expansion rate of 180.2% ~ 190.5%, water absorption amount per unit area of ^{1.61g / cm 2 ~ 1.74g / cm} 2, per unit area and the water retention 1.08g / cm ² Cm ^2. The stretchable adhesive band induces the volume expansion direction of the porous polyurethane foam having a large absorption capacity for blood and exudates from the wound to the wound side to directly press the wound, Gt; a < / RTI > dressing hemostatic pad.

The present invention also relates to the above-mentioned laminated alginate nonwoven fabric; A dressing hemostatic pad characterized in that the center of the area of the polyurethane foam (Foam) and the stretchable adhesive band is located on the same vertical line.

The adhesive band may be composed of a support band and an adhesive on one side of the support band, and the support band may be composed of at least one of PP, PVC, PU, PE, Nylon and PET. A hemostatic pad is provided.

The present invention also provides a method of manufacturing dressing hemostatic pads comprising the steps of: applying a support band adhesive of an adhesive band; Forming a polyurethane foam; Linking the polyurethane foam and an alginate nonwoven fabric; And a step of cutting the polyurethane foams and the alginate nonwoven fabric to a predetermined size to attach one side of the polyurethane foam to an adhesive band, wherein a contact portion between the polyurethane foam and the adhesive band is located inside the contact surface of the adhesive band, The thickness of the polyurethane foam 120 is greater than the thickness of the alginate nonwoven fabric and the thickness of the alginate nonwoven fabric is 0.1 cm to 5 cm , the one or a plurality are used as the alginate non-woven fabric and polyurethane foam volume expansion coefficient initial 24 hours 180.2% ~ 190.5%, water absorption amount per unit area of ^{1.61g / cm 2 ~ 1.74g / cm} 2, per unit area and moisture retention while There are features ^{1.08g / cm 2 ~ 1.32g / cm} 2, the adhesive band is absorbed, the volume change into the wound exudate to induce volume expansion according to W provides hemostasis dressing pad production bangbeopreul which is characterized in that to the surface scratches the expanded polyurethane foam by the pressure in the direction pressure hemostasis.

The present invention also relates to the above-mentioned laminated alginate nonwoven fabric; Wherein the center of the area of the polyurethane foam (Foam) and the stretchable adhesive band is located on the same vertical line.

The present invention also provides a method of manufacturing a dressing hemostatic pad characterized in that the support band can be composed of at least one of PP, PVC, PU, PE, Nylon and PET.

The alginate nonwoven fabric of the present invention is excellent in absorption and biocompatibility when used on a wound site and has an excellent hemostatic effect.

Further, the present invention is characterized in that the polyurethane foam is compressed and hemostated by excellent absorption power and volume expansion.

In addition, the present invention is characterized in that the polyurethane foam and the alginate nonwoven fabric are combined with each other to reduce the infection rate by reducing the number of dressing exchanges by the synergistic effect of the absorption power.

1 is a sectional view of a dressing hemostatic pad of the present invention.
2 is a top view of a dressing hemostatic pad of the present invention.
3 is a view showing the first replacement cycle of the dressing hemostatic pad of the present invention.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. First, it should be noted that, in the drawings, the same components or parts are denoted by the same reference numerals whenever possible. In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted so as to avoid obscuring the subject matter of the present invention.

As used herein, the terms " about, " " substantially, " " etc. ", when used to refer to a manufacturing or material tolerance inherent in the stated sense, Accurate or absolute numbers are used to help prevent unauthorized exploitation by unauthorized intruders of the referenced disclosure.

The present invention relates to a dressing hemostatic pad (100), comprising: an alginate nonwoven fabric (110) excellent in hydrophilicity, hemostatic function and biocompatibility; A polyurethane foam 120 having excellent absorbing ability and a stretchable adhesive band 130 are stacked in this order.

FIGS. 1 and 2 are views showing a cross section and a plane view of the present invention, wherein an alginate nonwoven fabric 110, a polyurethane foam 120, and an adhesive band 130 facing each other are sequentially connected.

The alginate in contact with the skin is excellent in hydrophilicity and biocompatibility and absorbs the blood or exudates generated in the wound area. It maintains the adhesiveness with the wound surface and the wetting environment to accelerate the epithelium and to produce the granulation tissue It can help promote.

The present invention is a natural substance that constitutes the cell membrane and intercellular material of brown algae, which are most distributed among marine organisms. Alginate fibers are prepared and used in the form of nonwoven fabric to improve the physical properties and mechanical strength of alginate.

The alginate fibers of the present invention alginate nonwoven fabric (110) can be obtained by dissolving sodium alginate in distilled water and then wet-spinning through a coagulation bath using calcium chloride. The fibers may be cut into short fibers and then pressed into a nonwoven fabric by needle punching or calendering.

The alginate nonwoven fabric may be composed of calcium alginate fibers. When blood or exudates are absorbed, the calcium ions of the calcium alginate fibers are replaced with sodium ions in blood or exudates to gel, and the gelled fibers are easily adhered to the wound surface, To maintain a useful humid environment, and furthermore, the substituted calcium ion is one of the blood coagulation factors and serves to help hemostasis of wound.

The thickness of the alginate nonwoven fabric 110 is suitably at least 0.1 cm or more, preferably 0.3 to 5 cm or less, depending on the wound, and two or more layers may be used in consideration of the thickness of the nonwoven fabric.

As shown in FIG. 1, the alginate nonwoven fabric 110 may have a size equal to or smaller than that of the grounded polyurethane foam 120, and the size of the area of the alginate nonwoven fabric 110 is not limited to the area of the polyurethane foam 120.

The present invention increases absorption of blood and exudates by using a polyurethane foam 120 laminated on one side of an alginate nonwoven fabric 110. The polyurethane foam structure is a porous structure with excellent absorbency and the absorbed foam structure is bulged more than the first.

Since the expanded polyurethane foam 120 and the adhesive band 130 including the expanded polyurethane foam 120 are expanded in a compressed state on the skin, the elastic expansion of the foam and the elasticity of the adhesive band 130 cause the wound And the area of the wound is expanded.

Therefore, by pressing the damaged blood vessels to physically block bleeding and blood clotting time is given to help the hemostasis.

Also, since the two layers of the alginate nonwoven fabric 110 and the polyurethane foam 120 are laminated, the absorbing power is doubled, and the need to replace the dressing material several times is reduced, thereby reducing the risk of infection due to the external exposure frequency of the wound It is effective.

The adhesive band 120 for adhering and fixing the dressing pad of the present invention to the skin may be composed of a support band and an adhesive on one side and the support band may be composed of at least one of PP, PVC, PU, PE, Nylon and PET have.

In addition to the adhesive effect of adhering the dressing material to the skin, the adhesive band shields external contaminants and is excellent in stretchability and elasticity,

The inner polyurethane foam 120 absorbs the exudates, compresses the wound with the expanded volume, and induces a volume change due to the volume expansion to the wound side, resulting in a compression hemostatic effect.

The present invention also provides a method for manufacturing dressing hemostatic pads comprising the steps of: applying an adhesive to a support of an adhesive band; Forming a polyurethane foam; Linking the alginate nonwoven fabric adhering to the polyurethane foam; And a step of cutting the bound polyurethane foam and the alginate nonwoven fabric to a certain size and adhering to the adhesive band.

The invention may be better understood by reference to the following examples, which are for the purpose of illustration only and are not intended to be limiting or to limit the scope of the appended claims.

Example  One

(G / cm < ² >), the amount of storage per unit area (g / cm < ² >) and the amount of storage per unit area (g / cm < ² >) of a polyurethane foam having an area of 5 cm x 5 cm and a thickness of 0.5 cm, cm < ² >) and the first dressing exchange period.

Example  2

Under the same conditions as in Example 1, the alginate polyurethane foam was 0.6 cm thick, and the alginate nonwoven fabric thickness was 0.4 cm.

Example  3

Under the same conditions as in Example 1, the polyurethane foam was 0.7 cm thick, and the alginate nonwoven fabric thickness was 0.3 cm.

Comparative Example  One

Measure the aspect 5cm × 5cm area and volume thickness of the non-woven fabric of alginate 1.0cm expansion coefficient (%) and the absorption amount per unit area (g / cm ^2), the hold-unit area (g / cm ²⁾ and the first dressing change intervals.

Comparative Example  2

Measure the aspect 5cm × 5cm area and volume thickness of the non-woven fabric of alginate 1.0cm expansion coefficient (%) and the absorption amount per unit area (g / cm ^2), the hold-unit area (g / cm ²⁾ and the first dressing change intervals.

※ Volume Expansion Rate ( % ) Test method

1) Measure the initial volume (A) by cutting the sample to a size of 5cm × 5cm. 2) Distilled water is immersed in the sample at a ratio of 40 times the initial weight of the sample. For 24 hours. 3) After 24 hours, take out the sample again and wipe off the surface water using a tissue paper, and then measure the sample volume (B) after absorbing the distilled water.

Expansion ratio (%) = (B-A) / A * 100

※ Absorption amount per unit area (g / cm ² )

1) Weigh the sample (5 × 5cm) and weigh the weight (W1). 2) Measure the DW to ± 0.5g and add 40 times the weight of the sample. , 3) Leave the sample in a thermostat at 37 ± 1 ℃ for 24 hours, measure the weight (W2) after twisting the sample for 30 seconds using tweezers.

(G / cm < ² >) = (W2-W1) / 25

(W1: initial weight (g), W2: weight (g) of sample after 24 hours)

※ Water content per unit area (g / cm ² )

1) Using a Convection Oven, an electronic precision scale, and a crimp weighing device (1.36kg), 1) measure the initial weight (A) of the sample by cutting it to 5cm x 5cm and the distilled water is 40 times And stored in a 37 ° C oven for 24 hours. 2) After 24 hours, take out again, press for 30 seconds using 1.36kg compression weight, and measure weight (B) again.

(G / cm ² ) = (BA) / 25

division Volume Expansion Rate (%) Per unit area
Absorption (g / cm ² ) Water content per unit area (g / cm ² ) 1st dressing
Replacement cycle (hr) Example 1 180.2 1.61 1.08 32.05 Example 2 182.6 1.65 1.12 33.54 Example 3 190.5 1.74 1.32 34.62 Comparative Example 1 147.5 0.39 0.31 21.35 Comparative Example 2 172.4 1.29 0.75 23.16

Examples 1 to 3 in which the polyurethane foam 120 and the alginate nonwoven fabric 110 are laminated are shown in Table 1 as volume expansion rate (%), water absorption per unit area (g / cm ² ), water content per unit area (g / cm ² ) It can be seen that the volume expansion rate, the amount of absorption per unit area, and the holding amount are superior to the comparative examples in which the polyphenylene sulfide (120) or the alginate nonwoven fabric (110) alone is used. As shown in FIG. 3, 2, the dressing exchange period is relatively long, and in particular, it can be seen that the dressing changing period of the third embodiment is more than 32 hours.

It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the inventions. It will be clear to those who have knowledge of.

100: dressing hemostatic pad 110: alginate nonwoven fabric
120: polyurethane foam 130: adhesive band

Claims (6)

In a dressing hemostatic pad,
An alginate nonwoven fabric having excellent hydrophilicity, hemostatic effect and biocompatibility;
A polyurethane foam (Foam) excellent in absorption ability and a stretchable adhesive band capable of being adhered to the skin are stacked in order,
Wherein the contact portion of the polyurethane foam and the adhesive band is located inside the contact surface of the adhesive band,
The alginate nonwoven fabric is smaller than the area of the grounded polyurethane foam 120,
The constituent fibers of the alginate nonwoven fabric are calcium alginate fibers obtained by dissolving sodium alginate in distilled water and then wet-spinning through a coagulating bath using calcium chloride,
The thickness of the polyurethane foam 120 is greater than the thickness of the alginate nonwoven fabric,
One of the alginate nonwoven fabrics has a thickness of 0.3 cm to 5 cm,
The alginate non-woven fabric and polyurethane foam has an initial 24 hours volume expansion coefficient ~ 180.2% 190.5%, water absorption amount per unit area of 1.61g / cm ² ~ 1.74g / cm ^2, per unit area and moisture retention 1.08g / cm ² ~ 1.32g / cm < ² >
Wherein the stretchable adhesive band is characterized by inducing a compressive hemostasis by directing a volume expansion direction of a porous polyurethane foam having a large absorption capacity for blood and exudates from the wound toward the wound and directly pressing the wound.
The method according to claim 1,
The laminated alginate nonwoven fabric; Characterized in that the center of the area of the polyurethane foam (Foam) and the stretchable adhesive band is located on the same vertical line.
The method according to claim 1,
Wherein the adhesive band comprises a support band and an adhesive on one side of the support band,
Characterized in that the support band can be composed of at least one of PP, PVC, PU, PE, Nylon and PET.
A method for manufacturing a dressing hemostatic pad,
Applying a support band adhesive of an adhesive band;
Forming a polyurethane foam;
Linking the polyurethane foam and an alginate nonwoven fabric;
And cutting the laminated polyurethane foam and the alginate nonwoven fabric to a predetermined size to adhere the one side of the polyurethane foam to an adhesive band,
Wherein the contact portion of the polyurethane foam and the adhesive band is located inside the contact surface of the adhesive band,
The alginate nonwoven fabric is equal to or smaller than the area of the grounded polyurethane foam 120,
The thickness of the polyurethane foam 120 is greater than the thickness of the alginate nonwoven fabric,
The thickness of one alginate nonwoven fabric is 0.3 cm to 5 cm,
The alginate non-woven fabric and polyurethane foam volume expansion rate 180.2% during the initial 24 hours to 190.5%, water absorption amount per unit area of ^{1.61g / cm 2 ~ 1.74g / cm} 2 And a moisture content per unit area of 1.08 g / cm ² to 1.32 g / cm ² ,
Wherein the adhesive band absorbs the exudate and pushes the expanded polyurethane foam toward the wound surface direction by inducing a volume change due to volume expansion to the wound side, thereby enabling the pressurized hemostasis.
5. The method of claim 4,
The laminated alginate nonwoven fabric; Characterized in that the center of the area of the polyurethane foam (Foam) and the stretchable adhesive band is located on the same vertical line.
5. The method of claim 4,
Wherein the support band comprises at least one of PP, PVC, PU, PE, Nylon, and PET.

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