KR20170116737A - roller type applicator for attaching micro needle - Google Patents

Abstract

A roller type applicator for attaching a micro needle is disclosed. A roller type applicator for attaching a microneedle according to the present invention comprises a microneedle tape having a microneedle patch formed on one surface thereof with a plurality of microneedles and a protective sheet attached to the back surface of the microneedle patch, A pressing portion for pressing the micro needle patch of the microneedle tape wound on the feeding roller in a state in contact with the skin to attach the micro needle patch to the skin, .

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention [0001] The present invention relates to a roller type applicator for attaching a micro needle,

The present invention relates to a roller type applicator for microneedle attachment.

Numerous drugs and treatments for the treatment of diseases have been developed but the problem of passing biological barriers (eg, skin, oral mucosa and brain-vascular barrier) and the efficiency of drug delivery in delivering drugs into the body It still remains to be improved.

Drugs are generally administered orally in tablets or capsules, but they can not be effectively delivered by these methods of administration solely because of the large number of drugs digested or absorbed in the gastrointestinal tract or lost by the mechanism of the liver. In addition, some drugs can not spread effectively through the intestinal mucosa. Also, compliance with the patient is also a problem (for example, in the case of an intoxicated patient who should take the medication at certain intervals, or who can not take medication).

Another common technique for drug delivery is through the use of conventional needles. While this method is more effective than oral administration, it has problems that cause pain at the injection site and local damage of the skin, hemorrhage, and infection at the injection site.

To solve these problems, various microstructures including a microneedle have been developed. The micro needles developed so far are mainly used for in vivo drug delivery, blood collection, and in-vivo analyte detection.

However, in the past, micro-needles were fabricated in a patch form to penetrate the skin more accurately, and the micro-needles were attached to the skin by applying a force in the vertical direction. In addition, conventional appliances have applied micro-needles arrayed in array form to a certain area at a time.

This application method has a problem that it is impossible to load the patch due to the application of the vertical force, so that the patch is applied to the application part for each application.

In addition, strong force must be applied to evenly penetrate the micro-needle to deliver the entire array with one force, which resulted in pain.

In addition, since the conventional patch applying apparatus applies a constant area with a single force, there is a limitation in the application area, and there is a problem that it is impossible to precisely apply to wrinkles and joints where bending or uneven skin is uneven.

Korean Patent Publication No. 10-2015-0028248

An embodiment of the present invention provides a roller-type applicator for attaching a micro needle, which can be used several times in a single charge with a microneedle patch in the form of a roll, and can control the application amount of the microneedle patch.

According to an aspect of the present invention, there is provided a micro needle pad comprising a microneedle patch having a plurality of microneedles formed on one surface thereof and a protective sheet attached to a back surface of the microneedle patch, a feeding roller on which the microneedle tape is wound, A microneedle patch of the microneedle tape wound on the skin, a pressing part for pressing the microneedle patch on the skin in contact with the skin to attach the microneedle patch to the skin, and a collection roller on which the protective sheet separated from the microneedle patch is wound, A roller type applicator for attachment is provided.

The pressing unit may include a pressure roller that presses the microneedle patch toward the skin while rotating and passes the protective sheet separated from the microneedle patch to a collection roller disposed at the rear.

At this time, the microneedle patches may be attached to one side of the protective sheet at a predetermined spaced distance.

The case may further include a case housing the supply roller, the pressing portion, and the collection roller, wherein the case may be provided with an opening that exposes a part of the pressing portion to the outside.

At this time, at least two or more of the feed roller, the pressurizing portion, and the collection roller may be connected to each other by the power transmission means and rotated at the same time.

At this time, the power transmitting means may be provided as a gear.

At this time, power generation means for providing a rotational power may be connected to at least one of the supply roller and the collection roller.

At least one of the feeding roller and the collecting roller may be provided with tension adjusting means for adjusting the tension of the microneedle tape.

The roller type applicator for attaching the microneedle according to an embodiment of the present invention includes a microneedle patch in the form of a roll so that it can be used several times by one charging, thereby improving convenience.

In addition, since the micro needle patch is sequentially attached by the curved surface of the pressing portion, the force applied to the micro needle can be concentrated, the micro needle can be infiltrated into the skin with a small force, Stimulation and pain transmitted to the patient may be alleviated.

In addition, since the area of the micro needle patch can be freely adjusted by adjusting the amount of the micro needle patch to be released, it is possible to control the drug delivery amount, and the micro needle patch can be attached So that a microneedle patch can be attached to the flat skin regardless of the application site of the body.

1 is a front view of a roller type applicator for attaching a micro needle according to an embodiment of the present invention.
2 is a front view of a microneedle tape which is a part of the present invention.
3 is a front view of a microneedle patch, which is a component of the present invention.
4 is a view showing a state in which a micro needle patch is attached to skin using a roller type applicator for attaching a micro needle according to an embodiment of the present invention.
5 is a cross-sectional view showing a micro rain patch attached to the skin.
6 is a perspective view of a roller type applicator for attaching a microneedle according to another embodiment of the present invention.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings, which will be readily apparent to those skilled in the art to which the present invention pertains. The present invention may be embodied in many different forms and is not limited to the embodiments described herein.

In order to clearly illustrate the present invention, parts not related to the description are omitted, and the same or similar components are denoted by the same reference numerals throughout the specification.

In addition, in the various embodiments, elements having the same configuration are denoted by the same reference numerals and only representative embodiments will be described. In other embodiments, only the configurations other than the representative embodiments will be described.

Throughout the specification, when an element is referred to as "comprising ", it means that it can include other elements as well, without excluding other elements unless specifically stated otherwise.

Hereinafter, a roller type applicator for attaching a microneedle according to an embodiment of the present invention will be described in detail with reference to the drawings.

In addition, although it has been described that the microneedles are attached to the skin in one embodiment of the present invention, it is disclosed in advance that the microneedles can be attached to various parts of the body including the skin.

1 is a perspective view of a roller type applicator for attaching a micro needle according to an embodiment of the present invention.

1, a roller type applicator for attaching a microneedle according to an embodiment of the present invention includes a microneedle tape 100, a feeding roller 200, a pressing part 300, a collecting roller 400, . ≪ / RTI >

In the present invention, the microneedle patch is provided in the form of a roll so that it can be used several times in a single charge, and the application amount of the micro needle patch can be adjusted.

Figure 2 is a front view of a microneedle tape, which is a component of the present invention, and Figure 3 is a front view of a microneedle patch, which is a component of the present invention

Referring to FIGS. 2 to 3, the micro needle patch 100 includes a micro needle patch 110 and a protective sheet 120. Here, the micro needle patch 110 includes a patch 111 and a plurality of micro needles 112 formed on a plurality of sides of the patch 111.

The patch 111 may be adhered to the skin 111 to maintain the skin 111 attached to the skin. The patch 111 or the micro needle 112 may be provided with a drug to be supplied into the body to be.

In addition, the micro needle patch 120 may be formed of a biodegradable material.

At this time, the protective sheet 120 is attached to the back surface of the micro needle patch 110 where the micro needle 112 is not formed. The protective sheet 120 may be attached to the back surface of the micro needle patch 110 and may be attached to the micro needle patch 110 through a separate adhesive material, have.

The microneedle tape 100 as described above is wound around the feeding roller 200. [

4 is a view showing a state in which a micro needle patch is attached to a skin using a roller type applicator for attaching a micro needle according to an embodiment of the present invention, Fig.

4 to 5, the microneedle tape 100 is wound around the feeding roller 200 such that the protective sheet 120 faces inward and the microneedle patch 110 faces outward. This is because the micro needle patches 110 of the micro needle film 100 wound on the feeding roller 200 are directed toward the skin 10. [

The microneedle patch 110 of the microneedle tape 100 wound on the feeding roller 200 can be brought into contact with the skin 10 and can be attached to the skin 10 while being pressed by a pressing portion which will be described later.

The pressing portion presses the microneedle patch 110 of the microneedle tape 100 wound on the feeding roller 200 in contact with the skin 10 to attach the microneedle patch 110 to the skin 10 .

At this time, the micro needle 112 penetrates the skin 10, and the drug 113 of the infiltrated micro needle 112 can be supplied into the body.

The micro needle patch 110 and the protective sheet 120 are separated from each other while the micro needle patch 110 is attached to the skin 10 while the protective sheet 120 is passed through the pressing portion, And is wound by the roller 400. [

The recovery roller 400 is provided to recover the protective sheet 120 separated from the micro needle patch 110 and the protective sheet 120 is wound around the collecting roller 400.

In the past, when attaching the micro needle patch to the skin, the micro needle patch was pressed against the skin in the vertical direction to attach the micro needle patch to the skin in order to more accurately penetrate the micro needle into the skin.

In addition, in the conventional case, the micro needle patches arranged in the form of arrays of micro needles were pressurized and attached to the skin at one time.

In such a conventional mounting method, a vertical force is simultaneously applied to the entire area of the microneedle patch, which makes it impossible to load the microneedle patch, so that the microneedle patch must be charged every time the microneedle patch is attached.

In addition, when the entire micro needle patch was pressurized and attached to the skin at once, it was forced to press with a stronger force to evenly infiltrate the micro needle into the skin, which caused pain.

In addition, in the conventional case, when a certain area is pressed with a single force to attach a micro needle patch to the skin, there is a limitation in the application area, and there is a problem that the application is not possible to the wrinkles and the joints where the skin is not uniform, .

However, in the case of the present invention, the microneedle tape 100 on the back surface is wound on the feeding roller 200 in the form of a roll so that it can be used many times by one charging.

As a result, the length of the micro needle patch attached to the skin can be adjusted in real time, and the amount of the drug supplied into the body through the micro needle patch can be precisely controlled.

1, the pressing portion presses the microneedle patch 110 toward the skin 10 side while rotating, and the protective sheet 120 separated from the microneedle patch 110 is returned to the collection roller 400, as shown in FIG.

The pressurizing roller 300 presses the micro needle patch 110 while rotating in the same direction as the feed roller 200. Thus, the micro needle patches 110 can be sequentially attached to the skin.

According to the present invention, the micro needle patches 110 can be attached to the skin under a force at a predetermined interval (for example, at intervals of one microwell) by the curved surface of the pressure roller 300, 112 can be precisely controlled.

Further, since the force applied to the micro needle 112 can be concentrated on a line-by-line basis, the micro needle 112 can be infiltrated into the skin 10 even with a smaller force than the conventional technique. Since the force applied to the micro needle 112 is reduced as described above, the pain applied to the patient can be alleviated.

Also, according to the present invention, the micro needle 112 can be vertically penetrated into the skin while sequentially attaching the micro needle patch 110 through the curved surface of the pressure roller 300, thereby overcoming the limit of the application area.

Further, since the pressure needle 300 is horizontally moved, the micro needle patch 110 adheres to the skin in accordance with the bending of the skin, and in the case of the corrugated area, the micro needle patch 110 is attached while spreading the wrinkles. The micro needle patch 110 can be attached to the flat skin regardless of the region.

Referring back to FIG. 2, the micro needle patches 110 may be attached to a surface of the protective sheet 120 at a predetermined distance D, and may be spaced apart from each other.

The interval D can be adjusted in various ways. When the microneedle patches 110 are arranged at a predetermined distance D as described above, the portion where the gap D is formed can be cut, so that the amount of the microneedle patches 110 attached to the skin can be adjusted .

In addition, the amount of the micro needle patch 110 adhered to the skin can be adjusted by adjusting the interval D of the micro needle patches 110, so that the amount of the drug supplied into the body can be controlled.

6 is a perspective view of a roller type applicator for attaching a microneedle according to another embodiment of the present invention.

6, the case 500 further includes a case 500 in which the supplying roller 200, the pressing part, and the collecting roller 400 are installed. In the case 500, a part of the pressing part is exposed to the outside An open aperture 510 may be formed.

In this case, the microneedle tape 100 wound on the feeding roller 200 is exposed to the outside together with the pressing portion through the opening 510 of the case 500, and the microneedle patch 110 is pressed by the pressing portion Can be attached to the skin.

At this time, the rotating shafts 210 and 410 of the feeding roller 200 and the collecting roller 400 may be fixed to the inner surface of the case 500.

On the other hand, when the pressing portion includes the pressing roller 300, one side 300 'of the pressing roller 300 may be exposed to the outside of the case 500 through the opening 510.

The microneedle tape 100 wound around the feeding roller 200 is exposed to the outside together with the pressure roller 300 through the opening 510 of the case 500 and the microneedle patch 110 is pressed against the pressure roller 300 and the protective sheet 120 separated from the micro needle patch 110 is wound around the collecting roller 400 disposed inside the case 500 via the pressure roller 300 Can be recovered.

In this case, the rotary shaft 310 of the pressure roller 300 may also be fixed to the inner surface of the case 500.

In this embodiment, a cutter may be provided at one end of the opening 510 of the case 500. The cutter is provided to cut the microneedle patch 110 when the attachment of the microneedle patch 110 to the skin 10 is completed.

Referring again to FIG. 6, at least two of the feed roller 200, the pressurizing portion, and the collecting roller 400 may be connected to each other by the power transmitting means and rotated at the same time.

When the feeding roller 200, the pressing portion, and the collecting roller 400 are connected to each other by the power transmitting means as described above, the operability can be improved because they rotate in conjunction with each other.

For example, when the pressing portion includes the pressing roller 300, when the pressing roller 300 is moved while the pressing roller 300 is in contact with the skin, the pressing roller 300 rotates, 200 and the collection roller 400 simultaneously rotate.

When the pressure roller 300 is rotated while pressing the microneedle tape 100 toward the skin side so as to attach the micro needle patch 120 to the skin, the feeding roller 200 rotates together with the pressure roller 300, The tape 100 is withdrawn from the supply roller 200 and the recovery roller 400 is rotated together with the supply roller 300 and the protective sheet 120 separated from the micro needle patch 110 through the pressure roller 300. [ Can be wound around the collection roller 400. [

At this time, the power transmitting means may be provided as gears 610, 620, 630.

6, gears 610, 620, and 630 are formed on the rotating shafts 210, 310, 410 of the feed roller 200, the pressure roller 300, and the collecting roller 400, and the gears 610, 620, 630 rotate in engagement with each other.

When the supply roller 200, the pressure roller 300 and the collecting roller 400 are connected by the gears 610, 620 and 630, when the pressure roller 300 rotates, the gears 610, 620, (200) and the collection roller (400) can rotate in succession.

The supply roller 200 and the pressure roller 300 rotate in the same direction and the collecting roller 400 can rotate in a direction opposite to the supplying roller 200 and the pressing roller 300. [

The gears 610, 620 and 630 of the feeding roller 200, the pressing roller 300 and the collecting roller 400 can be directly engaged and rotated, but the additional gears 610, 620 and 630 can be indirectly inserted Lt; / RTI >

In an embodiment of the present invention, a power generating means such as a motor or the like may be connected to at least one of the feeding roller 200 and the collecting roller 200.

When the power generating means is provided as described above, the feeding roller 200 and the collecting roller 400 can be rotated in a motorized manner. Thus, when the power generating means is operated, the microneedle tape 100 is unwound from the feeding roller 200 while the feeding roller 200 and the collecting roller 400 are rotated, The protective sheet 120 separated from the protective sheet 110 may be wound around the collecting roller 400.

At this time, a button for operating whether or not the power generation means generates power may be additionally provided, and a control portion for controlling the rotation speed, direction, and the like of the power generation means according to the operation of the button, .

Referring to FIG. 6, at least one of the feeding roller 200 and the collecting roller 400 may be provided with tension adjusting means for adjusting the tension of the micro needle tape 100.

The microneedle tape 100 and the protective sheet 110 are wound around the feeding roller 200 and the collecting roller 400, respectively.

At this time, when the micro needle tape 100 is pulled out from the feed roller 200 or the feed roller 200 and the collecting roller 400 idle during the process of winding the protective sheet 110 on the collecting roller 400 The micro needle tape 100 and the protective sheet 110 between the feeding roller 200 and the collecting roller 400 may not be tightened and loosened.

In this case, the feeding roller 200 and the collecting roller 400 are provided with tension adjusting means.

For example, the tension adjusting means may include grooves 211 and 411 provided on the rotating shafts 210 and 410 of the feed roller 200 and the collecting roller 400.

The grooves 211 and 411 may be formed to be inwardly concave in a straight shape.

When the grooves 211 and 411 are rotated by a flat screwdriver or the like while the microneedle tape 100 and the protective sheet 110 between the feed roller 200 and the collecting roller 400 are not tightened and loosened, The microneedle tape 100 and the protective sheet 110 between the take-up roller 400 and the take-up roller 400 can be rewound by the feed roller 200 and the take-

The roller-type applicator for attaching the microneedle according to the present invention as described above enables more precise and convenient delivery of drugs based on the microneedle.

In addition, by attaching the correct amount of the micro needle patches 110, it is possible to realize delivery of a fixed amount of drug, which is a solution to the problem of the micro needle patch 110, and accurate drug efficacy, The drug delivery reliability of the micro needle patch 110 can be increased.

In addition, the micro needle patch 110 can be attached with a smaller force than the conventional method of attaching the micro needle patch 110, so that the pain caused when the micro needle patch 110 is attached can be reduced, It is possible to maximize the merit of non-stimulation and non-stimulation of the user 110.

In addition, since the attachment area of the micro needle patch 110 can be freely adjusted, it is possible to flexibly change the drug delivery amount and to overcome the limitation of the application area due to the skin bending such as wrinkles and joints.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

100: Micro needle tape 110: Micro needle patch
111: Patch 112: Micro Needle
120: protective sheet 200: feed roller
210, 310, 410: central axis 211, 411: groove
300: pressure roller 400: collection roller
500: Case 610, 620, 630: Gear

Claims (8)

An applicator for attaching a micro needle to a skin to deliver a drug into the skin,
A microneedle tape including a microneedle patch having a plurality of microneedles formed on one surface thereof and a protective sheet attached to a back surface of the microneedle patch;
A feed roller on which the microneedle tape is wound;
A pressing portion for pressing the micro needle patch of the microneedle tape wound on the feeding roller in contact with the skin to attach the micro needle patch to the skin;
And a recovery roller on which a protective sheet separated from the micro needle patch is wound. The method according to claim 1,
Wherein the pressing portion includes a pressure roller for pressing the microneedle patch to the skin side while rotating and for passing the protective sheet separated from the microneedle patch to the collection roller disposed at the rear side. The method according to claim 1,
Wherein the micro needle patch comprises a plurality of one side of the protective sheet spaced apart from each other at a predetermined interval. ≪ RTI ID = 0.0 > 11. < / RTI > The method according to claim 1,
Further comprising a case having the feed roller, the pressurizing portion, and the collecting roller, wherein the case has an opening that is opened to expose a part of the pressurizing portion to the outside. The method according to claim 1,
Wherein at least two of the feeding roller, the pressing part, and the collecting roller are connected to each other by the power transmitting means and rotated at the same time. The method according to claim 1,
Wherein the power transmission means is a gear. ≪ RTI ID = 0.0 > 11. < / RTI > The method according to claim 1,
And a power generating means for providing a rotational power to at least one of the feeding roller and the collecting roller is connected to the roller-type applicator. The method according to claim 1,
Wherein at least one of the feeding roller and the collecting roller is provided with tension adjusting means for adjusting the tension of the micro needle tape.

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