KR20170043348A

KR20170043348A - Photosensitive toothpaste composition with excellent light absorption property

Info

Publication number: KR20170043348A
Application number: KR1020150143000A
Authority: KR
Inventors: 김현철
Original assignee: 에인에이 (주)
Priority date: 2015-10-13
Filing date: 2015-10-13
Publication date: 2017-04-21

Abstract

Collagen extract and chlorophyll extract are added as an effective ingredient to increase the light absorbance of light of a specific wavelength band without causing damage to the skin tissue in the oral cavity during the light emitting diode (LED) A photoreactive dentifrice composition excellent in light absorbability which can be maximized is disclosed.
The photoreactive dentifrice composition according to the present invention comprises 10 to 40 wt% of an abrasive, 20 to 50 wt% of a wetting agent, 0.5 to 5.0 wt% of a foaming agent, 0.1 to 3.0 wt% of a binder, 0.1 to 3.0 wt% of a collagen extract, 0.1 to 3.0% by weight of the extract and 10 to 60% by weight of the solvent.

Description

TECHNICAL FIELD [0001] The present invention relates to a photothermographic composition,

The present invention relates to a photoreactive dentifrice composition, and more particularly, to a photoreactive dentifrice composition which does not cause damage to the skin tissue in the oral cavity during light irradiation with an LED (light emitting diode) due to the addition of collagen extract and chlorophyll extract as an active ingredient, The present invention relates to a photoreactive dentifrice composition which is excellent in light absorbability, which can maximize the effect of phototherapy by increasing light absorption amount to light of a specific wavelength band.

Generally, tooth discoloration factors can be classified into extrinsic discoloration and endogenous discoloration. Exogenous tooth discoloration occurs when food waste, nicotine and tar components of cigarettes, coffee, tea, etc. are deposited on the surface of the teeth, or soft deposits on the tooth surface are stained by the pigment components. Endogenous tooth discoloration occurs in the teeth, An overdose of antibiotics by cyclins, or an aging phenomenon.

In order to prevent whitening and discoloration of teeth discolored by various causes, whitening toothpaste has long been commercialized and used.

To date, commercialized tooth whitening techniques include the most traditional method of strong polishing and the method of corroding the surface of teeth by controlling the pH of the product to strong acidity. As described above, the method of strong polishing is to simply whiten the surface of the tooth by physically polishing the surface to make the surface smoother and expect a whitening effect. However, since the teeth are excessively worn during long- There is a problem that the wear of the cervical spine is caused first and then the cervical spasticity is generated. In addition, the method of corroding the surface of the tooth by adjusting the pH of the product to strong acidity may not only increase the progress speed of the tooth cavity by decreasing the hardness of the teeth due to tooth damage caused by corrosion of the tooth surface, .

In order to solve this problem, recently, a light emitting diode (LED), which is widely used as a light source, has been attracting attention as a main light source of phototherapy, and studies have been actively conducted on an LED mounted toothbrush incorporating the same. In general, an LED is a semiconductor that emits light when a current is supplied, and not only can emit all light such as ultraviolet rays, visible rays, and infrared rays, but also has an advantage that output and color can be adjusted. In addition, since the energy can be lowered and only light of the desired wavelength can be emitted, it is suitable as a medical instrument since the side effect is small and it does not cause harm to other human tissues. Because of this, the US Food and Drug Administration (FDA) has authorized the use of visible and near infrared LEDs for human treatment.

Therefore, in recent years, efforts have been made to achieve disinfection in the oral cavity, alleviation of periodontal disease, and whitening effect of the teeth, by allowing the LED light irradiation to be performed in a non-contact manner using the LED-mounted toothbrush.

A related prior art is Korean Patent Registration No. 10-0951396 (published on Apr. 07, 2010), which discloses a dentifrice composition having excellent odor removal, plaque removal and antibacterial effect.

It is an object of the present invention to increase the amount of absorbed light for light of a specific wavelength range without causing damage to skin tissues in the oral cavity during light emitting diode (LED) irradiation, due to the addition of collagen extract and chlorophyll extract as an active ingredient To provide a photoreactive dentifrice composition excellent in light absorbability which can maximize a phototherapy effect.

In order to achieve the above object, a photoreactive dentifrice composition having excellent light absorptivity according to an embodiment of the present invention comprises 10 to 40 wt% of an abrasive, 20 to 50 wt% of a wetting agent, 0.5 to 5.0 wt% of a foaming agent, 0.1 to 3.0 wt% 0.1 to 3.0% by weight of collagen extract, 0.1 to 3.0% by weight of chlorophyll extract and 10 to 60% by weight of solvent.

The photoreactive dentifrice composition according to the present invention has a light absorption amount of 2.5 to 6.0 mW / cm ² upon irradiation with light having a wavelength of 600 to 700 nm due to the addition of collagen extract and chlorophyll extract as an active ingredient. , It is possible to maximize the effect of disinfecting the oral cavity, alleviating periodontal disease, and whitening effect of the teeth, when the LED-mounted toothbrush is irradiated with LED light in a noncontact manner, without any sense of discomfort or discomfort to the user.

In addition, the photoreactive dentifrice composition having excellent light absorbing properties according to the present invention is a natural material capable of absorbing photons in response to a light source of 600 to 700 nm which is known to be biologically safe and has a whitening effect on teeth, ), The collagen and chlorophyll extracts can be added together to realize the whitening effect of the teeth without addition of a separate whitening agent, and the disinfecting effect in the oral cavity and the effect of alleviating periodontitis can be attained to the user without any feeling of discomfort or discomfort .

Advantages and features of the present invention and methods of achieving them will become apparent with reference to the embodiments described hereinafter. It should be understood, however, that the invention is not limited to the disclosed embodiments, but is capable of many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, To fully disclose the scope of the invention to those skilled in the art, and the invention is only defined by the scope of the claims. Like reference numerals refer to like elements throughout the specification.

Hereinafter, a photoreactive dentifrice composition having excellent light absorbing properties according to a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings.

Photoreactive dentifrice composition

The photoreactive dentifrice composition having excellent light absorbing property according to the embodiment of the present invention is applied to the oral cavity of the user to increase the light absorption amount upon irradiation of light having a wavelength of 600 to 700 nm.

Therefore, the photoreactive dentifrice composition having excellent light absorbing property according to the embodiment of the present invention is preferably used together with the LED-mounted toothbrush, and the combination of the collagen extract and the chlorophyll extract as an active ingredient, It is possible to maximize the phototherapeutic effect by increasing the light absorption amount to light of a specific wavelength band without causing damage to the skin tissue in the user's mouth when irradiated with light having a wavelength of 600 to 700 nm.

To this end, the photoreactive dentifrice composition having excellent light absorptivity according to an embodiment of the present invention comprises 10 to 40 wt% of an abrasive, 20 to 50 wt% of a wetting agent, 0.5 to 5.0 wt% of a foaming agent, 0.1 to 3.0 wt% of a binding agent, 0.1 ~ 3.0 wt%, chlorophyll extract 0.1 ~ 3.0 wt%, and solvent 10 ~ 60 wt%.

The abrasive may be at least one selected from the group consisting of silica gel, precipitated silica, zirconium silicate, calcium monohydrogenphosphate, calcium monohydrogenphosphate anhydrous, hydrated alumina, and aluminum silicate.

The abrasive is preferably added at a content ratio of 10 to 40% by weight of the total weight of the photoreactive dentifrice composition. When the addition amount of the abrasive is less than 10% by weight, the abrasive effect can not be exhibited properly. On the other hand, if the amount of the abrasive added exceeds 40% by weight, tooth abrasion may occur due to excessive polishing.

The wetting agent is an essential base component for making ointment formulations. It prevents the toothpaste from drying and solidifying when exposed to the air, and provides gloss to the surface of the toothpaste. For example. As the wetting agent, at least one selected from glycerin, xylitol, polyethylene glycols, propylene glycol and the like may be used. At this time, the wetting agent is preferably added at a content ratio of 20 to 50% by weight of the total weight of the photoreactive dentifrice composition.

The foaming agent is added for the purpose of improving the feeling of use of the toothpaste, facilitating the cleaning action, and reducing the interfacial tension to easily remove foreign substances in the oral cavity. The foaming agent is preferably an anionic surfactant such as sodium lauryl sulfate. However, the foaming agent is not limited thereto, and may be a copolymer of polyoxyethylene polyoxypropylene (poloxamer), polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitan Nonionic surfactants such as fatty acid esters may also be used. At this time, it is preferable that the foaming agent is added at a content ratio of 0.5 to 5.0% by weight based on the total weight of the photoreactive dentifrice composition.

The binder is added for the purpose of bonding the solid powder component and the liquid component so that they are not separated. The binder may be any water-soluble polymer, and preferably at least one selected from carboxymethyl cellulose sodium, carrageenan, xanthan gum, etc. may be used. Such a binder is preferably added at a content ratio of 0.1 to 3.0% by weight of the total weight of the photoreactive dentifrice composition.

Collagen extract is a natural material that is able to absorb photon in response to a light source of 600 ~ 700nm wavelength, which is biologically safe and has skin moisturizing effect and wound healing effect because of its excellent mechanical rigidity and skin tissue binding ability. It is added to serve as a chromophore.

The collagen extract is preferably added in an amount of 0.1 to 3.0% by weight of the total weight of the photoreactive dentifrice composition, more preferably 1.0 to 1.5% by weight.

If the added amount of the collagen extract is less than 0.1% by weight, the complexing effect with the chlorophyll extract may be lost due to the insufficient amount of the collagen extract added. On the contrary, when the amount of the collagen extract added is more than 3.0% by weight, the cost of the raw material can be increased without further increase of the effect, which is not economical.

Chlorophyll extracts act to prevent infection, prevent spread of inflammation, inhibit pain, and have excellent efficacy in removing bad breath and increase light absorption through addition of collagen extract. Like the collagen extract, the chlorophyll extract acts as a chromophore that is biologically safe and capable of absorbing photons in response to a light source in the wavelength range of 600 to 700 nm.

The chlorophyll extract is preferably added in an amount of 0.1 to 3.0% by weight of the total weight of the photoreactive dentifrice composition, more preferably 1.0 to 1.5% by weight.

If the added amount of the chlorophyll extract is less than 0.1% by weight, the effect of adding the complex with the collagen extract is insignificant, so that it may be difficult to exhibit the optical absorption enhancing effect properly. On the contrary, when the amount of the chlorophyll extract is more than 3.0% by weight, the cost of the raw material increases more than the effect of increasing the light absorption, which is not economical.

These collagen extracts were found to have an effect of increasing the absorption of light depending on the blending ratio with the chlorophyll extract. That is, it is preferable that the collagen extract and the chlorophyll extract are added at a weight ratio of 1: 0.8 to 1: 1.2, and it is confirmed that when the collagen extract and the chlorophyll extract are added to the above range, the light absorption is maximum.

In addition, the photoreactive dentifrice composition having excellent light absorbing property according to an embodiment of the present invention may further include 1-hydroxy-cyclohexyl-phenyl-ketone. It is preferred that this 1-hydroxy-cyclohexyl-phenyl-ketone is added in a ratio of 0.5 to 3% by weight of the total weight of the photoreactive dentifrice composition. When this 1-hydroxy-cyclohexyl-phenyl-ketone was further added, it was confirmed through experiments that the light absorption reaction was promoted and the light absorption amount was further increased.

The photoreactive dentifrice composition having excellent light absorbing properties according to the embodiment of the present invention is a dentifrice composition having an average particle diameter of 2.5 to 6.0 mW / cm < ² > at a light irradiation of 600 to 700 nm due to the addition of collagen extract and chlorophyll extract as an active ingredient. When used in conjunction with an LED-mounted toothbrush having a light absorbing amount and non-contact type LED light irradiation, it is possible to maximize the effect of disinfecting the oral cavity, alleviating periodontal disease, and whitening effect of the tooth without feeling discomfort or discomfort to the user.

In addition, the photoreactive dentifrice composition having excellent light absorbing properties according to an embodiment of the present invention is a natural material capable of absorbing photons in response to a light source of 600 to 700 nm, which is known to be biologically safe and has a whitening effect on teeth By adding collagen extract and chlorophyll extract together with chromophore, the whitening effect of teeth can be realized without adding any whitening agent, and the user can be disinfected in the oral cavity and relieved of periodontitis without discomfort or discomfort. can do.

Example

Hereinafter, the configuration and operation of the present invention will be described in more detail with reference to preferred embodiments of the present invention. It is to be understood, however, that the same is by way of illustration and example only and is not to be construed in a limiting sense.

The contents not described here are sufficiently technically inferior to those skilled in the art, and a description thereof will be omitted.

1. Preparation of dentifrice composition

Example 1

30% by weight of silica gel as a polishing agent, 40% by weight of glycerin as a wetting agent, 3.5% by weight of sodium lauryl sulfate as a wetting agent, 1.5% by weight of carrageenan as a binder, 0.5% by weight of a collagen extract, 0.8% by weight of a chlorophyll extract and 23.7% And then stirred for 15 minutes to prepare a dentifrice composition.

Example 2

15% by weight of silica gel and 20% by weight of zirconium silicate as abrasives, 40% by weight of glycerin as wetting agent, 4% by weight of sodium lauryl sulfate as binder, 2% by weight of carrageenan as binder, 0.75% by weight of collagen extract, 0.75% 17.5% by weight of purified water was mixed and stirred for 15 minutes to prepare a dentifrice composition.

Example 3

35% by weight of silica gel as an abrasive, 35% by weight of xylitol as wetting agent, 4.0% by weight of sodium lauryl sulfate as binder, 1.0% by weight of xanthan gum as a binding agent, 1.0% by weight of collagen extract, 1.0% by weight of chlorophyll extract and 23% After mixing, the mixture was stirred for 15 minutes to prepare a dentifrice composition.

Example 4

30% by weight of zirconium silicate as an abrasive, 45% by weight of glycerin as a wetting agent, 3.0% by weight of sodium lauryl sulfate as a binder, 1.0% by weight of xanthan gum as a binder, 1.5% by weight of collagen extract, 1.5% by weight of chlorophyll extract, And the mixture was stirred for 15 minutes to prepare a dentifrice composition.

Example 5

35% by weight of silica gel as an abrasive, 35% by weight of glycerin as a wetting agent, 4.0% by weight of sodium lauryl sulfate as a binder, 1.0% by weight of xanthan gum as a binder, 2.0% by weight of collagen extract, 2.0% by weight of chlorophyll extract and 21% After mixing, the mixture was stirred for 15 minutes to prepare a dentifrice composition.

Example 6

A mixture of 35% by weight of silica gel as an abrasive, 40% by weight of glycerin as wetting agent, 4.0% by weight of sodium lauryl sulfate as binder, 1.0% by weight of xanthan gum, 1.0% by weight of collagen extract, 1.0% by weight of chlorophyll extract, -Phenyl-ketone and 17% by weight of purified water as a solvent were mixed and stirred for 15 minutes to prepare a dentifrice composition.

Comparative Example 1

35% by weight of silica gel as an abrasive, 45% by weight of glycerin as a wetting agent, 4.0% by weight of sodium lauryl sulfate as a binding agent, 1.0% by weight of xanthan gum as a binder and 15% by weight of purified water as a solvent were mixed and stirred for 15 minutes, .

Comparative Example 2

35% by weight of silica gel as an abrasive, 35% by weight of glycerin as a wetting agent, 4.0% by weight of sodium lauryl sulfate as a binder, 1.0% by weight of xanthan gum as a binder, 1.0% by weight of a collagen extract and 24% Lt; / RTI > to produce a dentifrice composition.

Comparative Example 3

35 wt% of silica gel as an abrasive, 40 wt% of glycerin as a wetting agent, 4.0 wt% of sodium lauryl sulfate as a binder, 1.0 wt% of xanthan gum as a binding agent, 1.5 wt% of chlorophyll extract and 18.5 wt% of purified water as a solvent, Lt; / RTI > to produce a dentifrice composition.

2. Property evaluation

Table 1 shows the results of measurement of the light absorption amount by wavelength for the dentifrice compositions prepared according to Examples 1 to 6 and Comparative Examples 1 to 3.

1) Light absorption measurement

3 g of the photoreactive dentifrice composition was coated on a 4 × 4 cm area of the dish surface of the polystyrene material and then the sample irradiance was measured at 600 nm, 620 nm, 630 nm, 660 nm, 680 nm, (MW / cm < ² >) was measured using a light source (Field Spec 4, ASD Inc, USA).

[Table 1]

As shown in Table 1, in the case of the dentifrice composition prepared according to Examples 1 to 6, due to the combined addition of collagen extract and chlorophyll extract as an active ingredient, it was found that when light of 600 to 700 nm wavelength was irradiated, Of 2.5 to 6.0 mW / cm < 2 >, and the light absorption amount exhibited a maximum at a wavelength of 630 nm. At this time, as the addition amount of collagen extract and chlorophyll extract increases, the light absorption amount also increases.

In particular, in the case of the dentifrice composition prepared according to Example 6, although the collagen extract and the chlorophyll extract were each added in an amount of 1% by weight, it can be confirmed that the light absorption amount by each wavelength band shows the maximum value, -Cyclohexyl-phenyl-ketone. &Lt; / RTI >

On the other hand, in the case of the dentifrice composition prepared according to Comparative Example 1 in which neither the collagen extract nor the chlorophyll extract was added, the light absorption amount was measured to be 0.7 mW / cm 2 or less.

Also, in the case of the dentifrice composition prepared according to Comparative Examples 2 and 3 in which only either the collagen extract or the chlorophyll extract was added, the light absorption amount was measured to be 1.3 mW / cm 2 or less, Able to know.

As can be seen from the above experimental results, when the collagen extract and the chlorophyll extract were added together, the light uptake was increased and the light uptake was changed depending on the addition amount of the collagen extract and chlorophyll extract.

Table 2 shows the test results of the whitening effect using the dentifrice composition prepared according to Examples 1 to 6 and Comparative Examples 1 to 3.

2) Whitening effect test

Cigarettes, coffee, tea, sugar, and calcium into a gel, then transferred to a bottom container of a motor-equipped device for rotation, and dental specimens extracted from 20 healthy adults were mixed with epoxy resin The specimens were prepared so that the exposed area was 2 mm x 2 mm, and the specimens were attached to a rotating plate and operated for 3 days to forcefully adhere them.

At this time, an incandescent lamp was installed at the center of the rotating plate to dry the stains attached to the specimen, thereby promoting the attachment of stains. On the last day, the specimens with stains were taken out, the whiteness index (a) was measured using a colorimeter, the specimens were fixed on a specially designed abrasive force gauge capable of reciprocating motion, . At this time, 1 g each of the dentifrice compositions prepared according to Examples 1 to 7 and Comparative Examples 1 to 3 was applied to the ends of the bristles, and the mixture was operated for 30 minutes so as to be reciprocated 90 times per minute while irradiating light having a wavelength of 630 nm. The specimens were taken out again and the degree of whiteness (ΔL, ba) was measured after measuring the whiteness (b) of the specimen using a colorimeter.

[Table 2]

As shown in Table 2, it was confirmed that the dentifrice compositions prepared according to Examples 1 to 6 were significantly increased in whiteness compared to the dentifrice compositions prepared according to Comparative Examples 1 to 3.

As a result of the above tests, it was confirmed that the dentifrice compositions prepared according to Examples 1 to 6 can be significantly improved in whitening effect compared with the dentifrice compositions prepared according to Comparative Examples 1 to 3.

Table 3 shows the results of testing the effect of removing the bad breath using the dentifrice composition prepared according to Examples 1 to 6 and Comparative Examples 1 to 3. [

3) Bad breath removal test

Forty - five subjects were asked to halt all oral environment management for 48 hours, then measure halitosis with halimetry and then divide into 9 groups with similar mean values. Each of the groups was soaked with the dentifrice composition prepared according to Examples 1 to 6 and Comparative Examples 1 to 3 in such a manner that light with a wavelength of 630 nm was irradiated using an LED-mounted toothbrush. The degree of bad breath was measured again 30 minutes after brushing. Thereafter, the dentifrice composition and the LED-mounted toothbrush were used for 28 days twice a day. Then, the subjects were summoned at 7 days, 14 days, 21 days, and 28 days, and the degree of bad breath was measured again 30 minutes after brushing, and the bad breath score according to the period of use Respectively.

[Table 3]

As shown in Table 3, when the dentifrice composition prepared according to Comparative Examples 1 to 3 was used, it was found that there was almost no change in the bad breath score according to the passage of time.

On the other hand, when the dentifrice composition prepared according to Examples 1 to 6 was used, it can be seen that the score of bad breath was remarkably decreased with time.

Based on the above experimental results, it was confirmed that the dentifrice composition prepared according to Examples 1 to 6 was effective in removing bad breath.

Although the preferred embodiments of the present invention have been disclosed for illustrative purposes, those skilled in the art will appreciate that various modifications, additions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims. These changes and modifications may be made without departing from the scope of the present invention. Accordingly, the scope of the present invention should be determined by the following claims.

Claims

10 to 40% by weight of an abrasive,
20 to 50% by weight of a wetting agent,
0.5 to 5.0% by weight of a foaming agent,
0.1 to 3.0% by weight of a binder,
0.1 to 3.0% by weight of collagen extract,
0.1 to 3.0% by weight of chlorophyll extract and
And a solvent: 10 to 60% by weight based on the total weight of the dentifrice composition.

The method according to claim 1,
The dentifrice composition
Wherein the composition is applied to the user's mouth to increase the amount of light absorbed when irradiated with light having a wavelength of 600 to 700 nm from the LED mounted on the toothbrush.

The method according to claim 1,
The collagen extract and chlorophyll extract
1: 0.8 to 1: 1.2 by weight based on the total weight of the photocurable dentifrice composition.

The method according to claim 1,
The dentifrice composition
And a light absorbing amount of 2.5 to 6.0 mW / cm < ² > when irradiated with light having a wavelength of 600 to 700 nm from the LED mounted on the toothbrush.

The method according to claim 1,
The dentifrice composition
0.5 to 3% by weight of 1-hydroxy-cyclohexyl-phenyl-ketone.