KR20160141751A - Her3-표적화 나노입자를 이용한 트라스트주맙-내성 her2+ 유방암의 표적화 - Google Patents

Her3-표적화 나노입자를 이용한 트라스트주맙-내성 her2+ 유방암의 표적화 Download PDF

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KR20160141751A
KR20160141751A KR1020167028017A KR20167028017A KR20160141751A KR 20160141751 A KR20160141751 A KR 20160141751A KR 1020167028017 A KR1020167028017 A KR 1020167028017A KR 20167028017 A KR20167028017 A KR 20167028017A KR 20160141751 A KR20160141751 A KR 20160141751A
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her2
breast cancer
therapy
cells
resistant
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Korean (ko)
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라리 케이. 메디나-카우
제시카 심즈
마이클 타구아임
크리스 한슨
시아오지앙 쿠이
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세다르스-신나이 메디칼 센터
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    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A61K47/48238—
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
    • A—HUMAN NECESSITIES
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    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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KR1020167028017A 2014-04-04 2015-04-04 Her3-표적화 나노입자를 이용한 트라스트주맙-내성 her2+ 유방암의 표적화 Ceased KR20160141751A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461975687P 2014-04-04 2014-04-04
US61/975,687 2014-04-04
PCT/US2015/024400 WO2015154059A2 (en) 2014-04-04 2015-04-04 Targeting trastuzumab-resistant her2+breast cancer with a her3-targeting nanoparticle

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KR20160141751A true KR20160141751A (ko) 2016-12-09

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US (2) US9850293B2 (cg-RX-API-DMAC10.html)
EP (1) EP3129066B1 (cg-RX-API-DMAC10.html)
JP (2) JP6728056B2 (cg-RX-API-DMAC10.html)
KR (1) KR20160141751A (cg-RX-API-DMAC10.html)
CN (1) CN106170305A (cg-RX-API-DMAC10.html)
AU (1) AU2015240460A1 (cg-RX-API-DMAC10.html)
BR (1) BR112016023025A2 (cg-RX-API-DMAC10.html)
CA (1) CA2943297A1 (cg-RX-API-DMAC10.html)
IL (1) IL248046B (cg-RX-API-DMAC10.html)
MX (1) MX2016013025A (cg-RX-API-DMAC10.html)
RU (1) RU2692104C2 (cg-RX-API-DMAC10.html)
WO (1) WO2015154059A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA201607375B (cg-RX-API-DMAC10.html)

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KR20200084819A (ko) * 2019-01-03 2020-07-13 주식회사 바이오이즈 pH 의존적 막 투과성 펩타이드를 이용한 약물 운반체 및 그것과 약물의 복합체

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RU2674146C2 (ru) 2013-05-08 2018-12-07 Седарс-Синай Медикал Центр Нацеленные корролы, проявляющие опухолевую токсичность и предназначенные для мрт
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JP6728056B2 (ja) 2014-04-04 2020-07-22 シーダーズ—シナイ メディカル センター Her3標的ナノ粒子によりトラスツズマブ耐性her2+乳癌を標的にすること
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WO2015109264A1 (en) 2014-01-17 2015-07-23 Cedars-Sinai Medical Center Receptor targeting constructs and uses thereof
JP6728056B2 (ja) 2014-04-04 2020-07-22 シーダーズ—シナイ メディカル センター Her3標的ナノ粒子によりトラスツズマブ耐性her2+乳癌を標的にすること
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Publication number Priority date Publication date Assignee Title
WO2020141930A1 (ko) * 2019-01-03 2020-07-09 김성천 피에이치 의존적 막 투과성 펩타이드를 이용한 약물 운반체 및 그것과 약물의 복합체
KR20200084819A (ko) * 2019-01-03 2020-07-13 주식회사 바이오이즈 pH 의존적 막 투과성 펩타이드를 이용한 약물 운반체 및 그것과 약물의 복합체

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IL248046A0 (en) 2016-11-30
US20180066033A1 (en) 2018-03-08
JP2020176123A (ja) 2020-10-29
EP3129066A2 (en) 2017-02-15
BR112016023025A2 (pt) 2018-01-16
WO2015154059A3 (en) 2015-11-19
EP3129066A4 (en) 2017-09-20
RU2016140214A (ru) 2018-05-08
AU2015240460A1 (en) 2016-09-15
MX2016013025A (es) 2017-04-27
JP6728056B2 (ja) 2020-07-22
CN106170305A (zh) 2016-11-30
ZA201607375B (en) 2018-11-28
RU2016140214A3 (cg-RX-API-DMAC10.html) 2018-11-23
US20160060316A1 (en) 2016-03-03
EP3129066B1 (en) 2020-08-12
JP2017514800A (ja) 2017-06-08
WO2015154059A2 (en) 2015-10-08
RU2692104C2 (ru) 2019-06-21
IL248046B (en) 2020-07-30
CA2943297A1 (en) 2015-10-08
US9850293B2 (en) 2017-12-26

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