KR20160112444A - Toothpaste composition and applying method of the same - Google Patents
Toothpaste composition and applying method of the same Download PDFInfo
- Publication number
- KR20160112444A KR20160112444A KR1020150038202A KR20150038202A KR20160112444A KR 20160112444 A KR20160112444 A KR 20160112444A KR 1020150038202 A KR1020150038202 A KR 1020150038202A KR 20150038202 A KR20150038202 A KR 20150038202A KR 20160112444 A KR20160112444 A KR 20160112444A
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- South Korea
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- weight
- gel
- collagen
- water
- peppermint oil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
Description
More particularly, the present invention relates to a dentifrice composition comprising a first gel containing collagen and the like and a second gel containing ammonium hydrogen phosphate, A second gel, and a method of applying the same.
The toothpaste is composed of various components depending on the product. In general, silica, calcium, magnesium, alumina and the like are used as an abrasive. The abrasive is useful for mechanical cleaning of the teeth, If the shape is not proper, the dentin surface of the crown may be damaged. Therefore, the size of the particle should be approximately 1-20 μm and uniform, the shape should not have a very sensitive angle, and the hardness should be about 3 ° Are required as a condition of the mechanism.
Glycerol, sorbitol, xylitol, glycols and the like are used as a constituent wetting agent of the toothpaste. Fluoride (fluorine) is used for prevention of tooth decay. As a sterilizing agent for sterilization of the oral cavity, cationic As a tartar solubilizer, enzymes are used to inhibit the formation of plaques. Sodium salts with high osmotic pressure are used for the prevention of periodontal disease, and aminocaproic acid, allatoin, vitamins and the like are used.
These toothpastes (or dentifrice compositions) do not provide functions (or roles) for restoring tooth enamel and dentin minerals or for activating gingival regeneration.
An object of the present invention is to provide a dentifrice composition comprising a first gel containing collagen and the like and a second gel containing ammonium hydrogenphosphate and the like and a dentifrice composition for applying the first gel and the second gel to teeth, And a method of applying the same.
It is another object of the present invention to provide a dentifrice composition providing a dentifrice composition composed of a plurality of gels and a method of applying the dentifrice composition.
The dentifrice composition according to an embodiment of the present invention is a dentifrice composition containing collagen, which comprises 8.0 to 20.0% by weight of calcium nitrate, 0.2 to 1.0% by weight of collagen, 1.5 to 3.0% by weight of blancose, A first gel comprising 0.15% to 0.45% by weight of potassium persulfate, 0.1% to 0.3% by weight of potassium sorbate, 0.05% to 0.15% by weight of peppermint oil and the balance of% by weight water; 0.1 to 0.45 wt% of saccharin sodium, 0.1 to 0.3 wt% of potassium sorbate, 0.05 to 0.15 wt% of peppermint oil, and 0.1 to 5 wt% The% by weight and the rest% by weight may comprise collagen composed of a second gel comprising water.
A method of preparing a dentifrice composition according to an embodiment of the present invention is a method of manufacturing a dentifrice composition containing collagen, comprising the steps of: mixing calcium nitrate at a concentration of from 8.0 to 20.0% by weight, collagen at a level of from 0.2 to 1.0% Preparing a first gel comprising water, 0.01 to 3.0% by weight, saccharin sodium 0.15% to 0.45%, potassium sorbate 0.1% to 0.3%, peppermint oil 0.05% to 0.15% ; 0.1 to 0.45 wt% of saccharin sodium, 0.1 to 0.3 wt% of potassium sorbate, 0.05 to 0.15 wt% of peppermint oil, and 0.1 to 5 wt% % By weight and the balance% by weight may comprise preparing a second gel comprising water.
The method of applying a dentifrice composition according to an embodiment of the present invention is a method of applying a dentifrice composition containing collagen, comprising the steps of: applying a first gel comprising calcium nitrate, collagen, blanos, saccharin sodium, potassium sorbate, peppermint oil, ; Maintaining the state in which the first gel is applied for a predetermined first time of 50 seconds to 70 seconds; Applying a second gel comprising ammonium hydrogen phosphate, blanos, saccharin sodium, potassium sorbate, peppermint oil and water in the state that the first gel is applied; And maintaining the applied state of the second gel for a second predetermined time of 50 to 70 seconds.
As an example related to the present invention, the first gel may contain 8.0 wt% to 20.0 wt% of calcium nitrate, 0.2 wt% to 1.0 wt% of collagen, 1.5 wt% to 3.0 wt% of blannus, 0.15 wt% to 0.45 wt% of saccharin sodium 0.1% by weight to 0.3% by weight of potassium sorbate, 0.05% by weight to 0.15% by weight of peppermint oil, and the remaining weight% can include water.
As an example related to the present invention, the second gel may contain 5.0 wt% to 15.0 wt% of ammonium hydrogen phosphate, 1.5 wt% to 3.0 wt% of blanos, 0.15 wt% to 0.45 wt% of saccharin sodium, 0.1 wt% To 0.3% by weight, from 0.05% by weight to 0.15% by weight of peppermint oil, and the balance% by weight may comprise water.
The present invention relates to a dentifrice composition composed of a first gel containing collagen and the like and a second gel containing ammonium hydrogen phosphate or the like and applying the first gel and the second gel to the teeth and gums using the same, it is possible to restore the mineral content of the gum and subsurface dental enamel and to strengthen the mineral restorative anti-caries, gums restorative and anti-paradontosis .
The present invention also provides a dentifrice composition comprising a plurality of gels to improve adhesive, biocompatibility, bioavailability, prolongation of remineralization, and the like, And the stimulation can be regenerated.
1, 1 is a flowchart illustrating a method of manufacturing a dentifrice composition according to an embodiment of the present invention.
2 is a cross- 1 is a flowchart showing a method of applying a dentifrice composition according to an embodiment of the present invention.
It is noted that the technical terms used in the present invention are used only to describe specific embodiments and are not intended to limit the present invention. In addition, the technical terms used in the present invention should be construed in a sense generally understood by a person having ordinary skill in the art to which the present invention belongs, unless otherwise defined in the present invention, Should not be construed to mean, or be interpreted in an excessively reduced sense. In addition, when a technical term used in the present invention is an erroneous technical term that does not accurately express the concept of the present invention, it should be understood that technical terms that can be understood by a person skilled in the art can be properly understood. In addition, the general terms used in the present invention should be interpreted according to a predefined or prior context, and should not be construed as being excessively reduced.
Furthermore, the singular expressions used in the present invention include plural expressions unless the context clearly dictates otherwise. The term "comprising" or "comprising" or the like in the present invention should not be construed as necessarily including the various elements or steps described in the invention, Or may further include additional components or steps.
Furthermore, terms including ordinals such as first, second, etc. used in the present invention can be used to describe elements, but the elements should not be limited by terms. Terms are used only for the purpose of distinguishing one component from another. For example, without departing from the scope of the present invention, the first component may be referred to as a second component, and similarly, the second component may also be referred to as a first component.
Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings, wherein like reference numerals refer to like or similar elements throughout the several views, and redundant description thereof will be omitted.
In the following description, well-known functions or constructions are not described in detail since they would obscure the invention in unnecessary detail. It is to be noted that the accompanying drawings are only for the purpose of facilitating understanding of the present invention, and should not be construed as limiting the scope of the present invention with reference to the accompanying drawings.
Hereinafter, the dentifrice composition according to the present invention and its application method will be described in detail with reference to FIGS. 1 and 2. FIG.
1, 1 is a flowchart illustrating a method of manufacturing a dentifrice composition according to an embodiment of the present invention.
First, it is based on calcium nitrate tetrahydrate (Ca (NO 3 ) 2 ), collagen, blanose, sodium saccharinate, potassium sorbate, peppermint oil, To prepare a first gel.
In other words, it is preferable that the calcium nitrate is selected from the group consisting of 8.0 wt% to 20.0 wt% of calcium nitrate, 0.2 wt% to 1.0 wt% of collagen, 1.5 wt% to 3.0 wt% of blanoz, 0.15 wt% to 0.45 wt% of saccharin sodium, 0.1 wt% , 0.05% by weight to 0.15% by weight of peppermint oil, and the remaining weight% based on water to 100% of the total weight (or by mixing the remaining components with water).
Here, the collagen is a major connective tissue protein and is contained in the gum and enamel protein matrix.
In addition, the collagen is non-toxic, non-carcinogenic, non-antigenic, and has high regeneration and hydration functions, high biocompatibility, It has an active substance and an aggregate for the drug, and is biodegradable.
In addition, the collagen is a major substrate protein produced in fibroblasts of the skin and exists in extracellular epilepsy, and is an important protein occupying 30% of the total weight of the bioprotein, and has a solid triple helix structure. In addition, the main functions of the collagen include mechanical rigidity of the skin, resistance of connective tissues and binding force of tissues, support of cell adhesion, induction of cell division and differentiation (when organism growth or wound healing).
In addition, the calcium nitrate is a source of calcium ions that restore the mineral content of the hard tissue and form brushite microcrystals.
In addition, the blannus is a stabilizer.
In addition, the saccharin sodium is a sweetener.
Also, the potassium sorbate has an inflammatory action.
In addition, the peppermint oil is perfume and aromatherapy.
Further, the water is a solvent (or dissolvent) (S110).
A second gel is then prepared based on ammonium hydrogen phosphate, blanos, sodium saccharin, potassium sorbate, peppermint oil and water.
In other words, it is preferable to use an aqueous solution containing 5.0 wt% to 15.0 wt% of ammonium hydrogen phosphate, 1.5 wt% to 3.0 wt% of blanos, 0.15 wt% to 0.45 wt% of saccharin sodium, 0.1 wt% 0.15% by weight of water and the balance of water (or the remaining weight% is based on water and the total weight ratio is 100%).
Here, the ammonium hydrogen phosphate is a component forming a brushite, and maintains calcium ions in the link and the tooth structure (S120).
2 is a cross- 1 is a flowchart showing a method of applying a dentifrice composition according to an embodiment of the present invention.
First, the first gel is applied to teeth, gums and the like. Wherein the first gel comprises 8.0 to 20.0% by weight of calcium nitrate, 0.2 to 1.0% by weight of collagen, 1.5 to 3.0% by weight of blannus, 0.15 to 0.45% by weight of saccharin sodium, % To 0.3% by weight, peppermint oil 0.05% to 0.15% by weight, and the balance% by weight, water.
Also, the applied state is maintained for a preset first time of 50 to 70 seconds (generally 60 seconds).
For example, the first gel according to the user's brushing is applied to teeth, gums, and the like.
As described above, since the first gel contains collagen, when the first gel is applied to teeth, gums and the like, fitness to teeth and gum tissue, adhesion and the like are improved, and the gel component Long-term preservation, and calcium ions can penetrate deep into dental hard tissues (S210).
Thereafter, in a state in which the first gel is applied, a second gel is applied on the first gel.
That is, the second gel is applied to teeth, gums and the like in a state in which the first gel is applied. Wherein the second gel comprises from 5.0 to 15.0% by weight of ammonium hydrogen phosphate, from 1.5 to 3.0% by weight of blanose, from 0.15 to 0.45% by weight of saccharin sodium, from 0.1 to 0.3% by weight of potassium sorbate, From 0.05% to 0.15% by weight of oil and the balance% by weight of water.
Also, the coated state is maintained for a second predetermined time of 50 seconds to 70 seconds (generally 60 seconds).
As an example, the second gel according to the additional brushing of the user is applied to teeth, gums and the like.
As such, in the dental treatment with the second gel, the ammonium hydrogen phosphate leads to brushite microcrystals by interaction with calcium ions.
In addition, due to the presence of collagen, during the application of the second gel, the process leads to the formation of small crystals up to the nanocrystal that interact with the enamel protein matrix, which forms a similar structure to the tooth hard tissues.
The presence of this collagen creates a colloid protection effect that stabilizes the bristite colloid particles and prevents aggregation and coagulation of each other.
All of these increase the mineral content recovery effect and restore the dental enamel structure.
The collagen is also applied to the teeth and / or gums to stimulate gingival regeneration, reduce inflammation, and form a thin film on the tooth and gum surface to aid wound healing.
At this time, the operation of rinsing the inside of the oral cavity is not performed while the first gel and the second gel are kept coated.
That is, the first gel and the second gel may be applied without washing the coated first and second gels (S220).
Thus, the process of applying the first gel and the second gel can be performed at predetermined time intervals (for example, 12 hours intervals twice a day).
As described above, the embodiment of the present invention is a dentifrice composition composed of a first gel containing collagen and the like and a second gel containing ammonium hydrogen phosphate or the like, and a first gel and a second gel Gel, respectively, to restore the mineral content of the tooth enamel surface and gums, and to strengthen mineral restorative cavities, gum regeneration, and anti-parasitic infections.
Embodiments of the present invention also provide a dentifrice composition comprising a plurality of gels as described above to improve adhesion, biocompatibility, bioavailability, prolongation of mineral content, improve gum status, Regenerated.
It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or essential characteristics thereof. Therefore, the embodiments disclosed in the present invention are intended to illustrate rather than limit the scope of the present invention, and the scope of the technical idea of the present invention is not limited by these embodiments. The scope of protection of the present invention should be construed according to the following claims, and all technical ideas within the scope of equivalents should be construed as falling within the scope of the present invention.
The present invention relates to a dentifrice composition composed of a first gel containing collagen and the like and a second gel containing ammonium hydrogen phosphate or the like and applying the first gel and the second gel to the teeth and gums using the same, And the mineral content of the gums can be restored and the mineral restoration ability, gum regeneration, anti-parasitic infection and the like can be strengthened, and it can be widely used in dentifrice composition field, tooth care field, dental field, and the like.
Claims (5)
A mixture of calcium nitrate 8.0 wt% to 20.0 wt%, collagen 0.2 wt% to 1.0 wt%, blanose 1.5 wt% to 3.0 wt%, saccharin sodium 0.15 wt% to 0.45 wt%, potassium sorbate 0.1 wt% 0.05% to 0.15% by weight of peppermint oil and the balance weight% of water comprises a first gel comprising water; And
0.1 to 0.45% by weight of sodium saccharin, 0.1 to 0.3% by weight of potassium sorbate, 0.05 to 0.15% by weight of peppermint oil, 0.05 to 5% by weight of sodium hydrogen carbonate, 5.0 to 15.0% by weight of ammonium hydrogenphosphate, 1.5 to 3.0% % ≪ / RTI > and the balance weight% comprises collagen consisting of a second gel comprising water.
A mixture of calcium nitrate 8.0 wt% to 20.0 wt%, collagen 0.2 wt% to 1.0 wt%, blanose 1.5 wt% to 3.0 wt%, saccharin sodium 0.15 wt% to 0.45 wt%, potassium sorbate 0.1 wt% Preparing a first gel comprising 0.05% to 0.15% by weight of peppermint oil and a balance of% by weight water; And
0.1 to 0.45% by weight of sodium saccharin, 0.1 to 0.3% by weight of potassium sorbate, 0.05 to 0.15% by weight of peppermint oil, 0.05 to 5% by weight of sodium hydrogen carbonate, 5.0 to 15.0% by weight of ammonium hydrogenphosphate, 1.5 to 3.0% % ≪ / RTI > and the balance weight percent comprises preparing a second gel comprising water.
Applying a first gel comprising calcium nitrate, collagen, blanose, sodium saccharin, potassium sorbate, peppermint oil and water;
Maintaining the state in which the first gel is applied for a predetermined first time of 50 seconds to 70 seconds;
Applying a second gel comprising ammonium hydrogen phosphate, blanos, saccharin sodium, potassium sorbate, peppermint oil and water in the state that the first gel is applied; And
And holding the second gel-coated state for a second predetermined time of 50 seconds to 70 seconds.
Wherein the first gel comprises:
A mixture of calcium nitrate 8.0 wt% to 20.0 wt%, collagen 0.2 wt% to 1.0 wt%, blanose 1.5 wt% to 3.0 wt%, saccharin sodium 0.15 wt% to 0.45 wt%, potassium sorbate 0.1 wt% 0.05% to 0.15% by weight of peppermint oil and the balance of% by weight of water.
Wherein the second gel comprises:
0.1 to 0.45% by weight of sodium saccharin, 0.1 to 0.3% by weight of potassium sorbate, 0.05 to 0.15% by weight of peppermint oil, 0.05 to 5% by weight of sodium hydrogen carbonate, 5.0 to 15.0% by weight of ammonium hydrogenphosphate, 1.5 to 3.0% % And the remaining weight% comprises water.
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KR1020150038202A KR20160112444A (en) | 2015-03-19 | 2015-03-19 | Toothpaste composition and applying method of the same |
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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KR100935211B1 (en) | 2008-12-30 | 2010-01-06 | 남지원 | Composition of toothpowder-paste containing wheat-flour and bamboo-salt, and manufacturing method thereof |
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KR100935211B1 (en) | 2008-12-30 | 2010-01-06 | 남지원 | Composition of toothpowder-paste containing wheat-flour and bamboo-salt, and manufacturing method thereof |
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