KR20160085506A - Hollow prosthesis - Google Patents

Abstract

The present invention relates to an artificial prosthesis and, specifically, to an artificial prosthesis for remarkably improving bone fusion adhesion between a natural bone of a human body and the artificial prosthesis. In particular, the artificial prosthesis comprises: a body unit for constituting the outer appearance of the artificial prosthesis; and a human body fusion surface unit disposed to cover the outer surface of the body unit, having a porous surface structure consisting of a plurality of fine grooves, and coming in contact with and fused with a natural bone of the human body. Each of the fine grooves comprises: a feeding opening unit formed in the outside of the human body fusion surface unit; and a cell filling unit connected with the feeding opening unit, formed in an inner thickness direction of the human body fusion surface unit, and serving as a space for growing and filling human body cells. The cell filling unit comprises a countergradient side surface unit formed in an inner thickness direction of the human body fusion surface unit in at least a part thereof.

Description

[0001] HOLLOW PROSTHESIS [0002]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an artificial prosthesis, and more particularly, to an artificial prosthesis that remarkably improves a bone fusion bonding force between a natural bone of a human body and an artificial prosthesis, while at the same time reducing manufacturing costs.

BACKGROUND ART In general, an artificial prosthesis is an artificial structure which, when a skeleton of a human body is broken or damaged, is replaced with a skeleton or a joint or a disk that is a diseased part, and then a bone is united with a natural bone of a human body, to be. Such artificial prostheses include, for example, an intervertebral disc implanted in place of a damaged spinal disc, a hip artificial prosthesis replacing a damaged joint, an internal fixation splint to support and strengthen the union of fractured bones by securing and supporting fractured bones, and the like have.

Thus, the artificial prosthesis is united with the natural bone of the human body, and the natural function of the affected bone can be restored by the union of the natural prosthesis and the natural bone.

In order for the artificial prosthesis to have the original mechanical characteristics (rigidity and strength) of the skeleton, the artificial prosthesis and the artificial prosthesis should have a strong fixing or binding force between the natural bone of the human body to be unionized.

To this end, the artificial prostheses according to the prior art have protrusions or protrusions on the contact surface with natural bone (for example, vertebrae) such as artificial prosthesis disclosed in Korean Patent Laid-open No. 10-2002-0071855, And a structure for improving the fixation force with the bone.

However, since the artificial prosthesis according to the related art does not have a wide area of union with the natural bone, there is a problem that when the union is completed, the bony union coupling force between the artificial prosthesis and the natural bone is not so high.

In addition, the artificial prosthesis according to the prior art has a problem in that the amount of the biocompatible material is large and the manufacturing cost is high.

Accordingly, an object of the present invention is to solve the problems of the prior art.

Specifically, it is an object of the present invention to provide an artificial prosthesis that improves a bony union coupling force between an artificial prosthesis and a natural bone.

According to an embodiment of the present invention, there is provided a bone union according to the present invention, comprising: a first union unit and a second union unit provided at both ends and fused to natural bones; And a support member connecting the first union unit and the second union unit, wherein the support member is a hollow member.

Preferably, the support member includes a first hollow member and a second hollow member surrounding the outer peripheral surface of the first hollow member.

Preferably, the first hollow member and the second hollow member are made of different biocompatible materials.

Preferably, the biocompatible material is one of a ceramic, a biocompatible metal and a biocompatible polymer.

Preferably, the hollow member has a plurality of perforations so as to have a network structure.

Preferably, the second hollow member, or the first hollow member and the second hollow member have a plurality of perforations so as to have a mesh structure.

Preferably, the first union portion, the second union portion, and the support member are integrally formed.

Preferably, the first union portion, the second union portion, and the first hollow member are integrally formed, and the second hollow member is configured such that the first union portion and the second union portion support each other And is coupled to the first supporting member, the first union unit, and the second union unit.

Preferably, the first union portion and the second union portion include a united body surface portion provided to cover the entire outer surface, and the united body surface portion has a porous surface structure composed of a plurality of fine grooves .

Preferably, each of the fine grooves has an inflow opening formed outside the unfused surface portion, and an inflow opening formed in the inner thickness direction of the unfused surface portion and communicating with the inflow opening, And a cell filling portion which is a space to be filled, wherein an inner side surface of the cell filling portion includes at least a part of a reverse gradient side portion.

In addition, preferably, the cell filling portion is provided with a very fine concave-convex portion on the inner side.

According to the present invention, since the porous surface structure is provided on the surface of the prosthesis, it is possible to remarkably improve the surface area of the bone union between the natural bone of the human body in which the prosthesis and the prosthesis are jointed, It is possible to remarkably improve the bony union force and / or fixation force between the prosthesis and the natural bone.

Further, according to the present invention, by providing the surface structure of the prosthesis with a reverse gradient side portion, the upper portion of the fine groove (that is, the upper portion of the reverse gradient side portion of the body fusion surface portion) Or the bone tissue, it is possible to further improve the bone-joining strength between the surface of the prosthesis and the bone formation and / or the natural bone bony union, and as a result, the tensile load applied to the artificial prosthesis and the natural bone And can have a further improved union and / or clamping force.

In addition, since the present invention is entirely hollow, the amount of expensive biocompatible material can be significantly reduced, and manufacturing cost can be significantly reduced.

1 is a schematic perspective view and partially enlarged vertical sectional view of an artificial prosthesis according to an embodiment of the present invention.
2 is a schematic perspective view and partially enlarged vertical sectional view of an artificial prosthesis according to another embodiment of the present invention.
3 is a schematic perspective view and partially enlarged vertical sectional view of an artificial prosthesis according to another embodiment of the present invention.
FIG. 4 is a partially enlarged longitudinal sectional view of an unfused surface portion according to an embodiment of the present invention; FIG.
Fig. 5 is a schematic partial enlarged longitudinal sectional view of the unfused surface portion according to the first further embodiment of Fig. 4; Fig.
FIG. 6 is a schematic partial enlarged vertical cross-sectional view of an unfused surface portion according to a second further embodiment of FIG. 4; FIG.
7 is a schematic enlarged plan view of Figs. 4 to 6. Fig.
FIG. 8 is a schematic partial enlarged vertical cross-sectional view of an unfused surface portion according to a third further embodiment of FIG. 4; FIG.
FIG. 9 is a partially enlarged vertical cross-sectional view of an unfused surface portion according to a fourth further embodiment of FIG. 4; FIG.
FIG. 10 is a schematic enlarged plan view of FIG. 9. FIG.
11 is a schematic partial enlarged plan view of an alternative embodiment of Fig.
12A and 12B are schematic longitudinal sectional views of an unfused surface portion according to a further embodiment of the present invention.
13 to 15 are schematic views of an artificial prosthesis according to a modified embodiment of the present invention.

Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings so that those skilled in the art can easily carry out the present invention. It should be noted that the drawings denoted by the same reference numerals in the drawings denote the same reference numerals whenever possible, in other drawings. In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear. And certain features shown in the drawings are to be enlarged or reduced or simplified for ease of explanation, and the drawings and their components are not necessarily drawn to scale. However, those skilled in the art will readily understand these details.

For reference, the artificial prosthesis described below includes the artificial disc between the vertebrae, the artificial bone, and the internal fixation splint that fixes the fractured bone. However, for clarity of explanation, the following description will be made with reference to a spinal artificial disk (see FIG. 1), an internal fixation splint (see FIG. 2), and an artificial bone (see FIG. 3).

1 is a schematic perspective view and partially enlarged vertical sectional view of an artificial prosthesis 100 according to an embodiment of the present invention.

1, an artificial prosthesis 100 according to an embodiment of the present invention is an interspinous artificial disk, which is an example of an artificial prosthesis, (For example, the cervical vertebrae or the like) located at the lower portion of the artificial prosthesis 100 and the lower vertebra bone (for example, the cervical vertebrae or the like) located at the lower portion of the artificial prosthesis 100, Of the prosthesis.

The artificial prosthesis 100 includes an upper member 110 and a lower member 110 which is rotatably connected to the upper member 110 at a predetermined angle in the forward and backward direction and / And a fixing member 130 for fixing the artificial prosthesis 100 to the lower surface of the upper vertebra bone and / or the upper surface of the lower vertebra bone.

The upper member 110 has an upper surface in surface contact with the lower surface of the upper vertebra and at least one fixing member 130 is provided on the upper surface of the upper member 110. Between the upper surface of the upper member 110 and the lower surface of the upper vertebra, new bone cells or bone tissue are generated with time, so that the lower surface of the upper vertebra is attached to the upper surface of the upper member 110 Bone union.

Similarly, the lower member 120 has a lower surface in surface contact with the upper surface of the lower vertebra, and at least one holding member 130 is provided on the lower surface of the lower member. Between the lower surface of the lower member and the upper surface of the lower vertebra, new bone cells or bone tissue are generated over time and the upper surface of the lower vertebra is united to the lower surface of the lower member.

The upper member 110 and the lower member 120 may be fixed to the upper member 110 and the lower member 120 with reference to the thickness direction (i.e., longitudinal section) of the prosthesis 100. [ And a body unfused surface portion 300 provided on a surface of the body portion 101. The body portion 101 is formed on the surface of the body portion 101,

At this time, the main body 101 and the unfused surface portion 300 may be formed separately. However, the present invention is not limited thereto, and the main body 101 and the unfused surface portion 300 may be integrally formed by a single process.

For example, the main body 101 may be manufactured by casting or injection molding, and a method of laminating the 3D printer on the surface of the manufactured main body may be performed to form the unfused surface portion 300. Alternatively, the main body 101 and the unfused surface portion 300 may be manufactured by a stacking method of a 3D printer as a whole.

The unfused surface portion 300 has a porous surface structure composed of a plurality of fine grooves 310 and the porous surface structure covers the entire outer surface of the main body portion 101 or covers a certain area or more. Therefore, the body fusion surface portion 300 can remarkably increase the surface area of the new bone cells to be produced and the union area. A detailed description of the human body fusion surface portion 300 will be described in more detail with reference to FIG. 4 to FIG.

2 is a schematic perspective view and partially enlarged vertical sectional view of an artificial prosthesis 100 according to another embodiment of the present invention.

2, an artificial prosthesis 100 according to another embodiment of the present invention is an internal fixation splint 200 for fracture treatment, which is an example of an artificial prosthesis 100. The artificial prosthesis 100 includes a fractured bone, The bone and the to-be-bonded portion B2 are arranged so as to surround the fractured bone and the portion to be contacted by the to-be-bonded portion B2 in a state of being in direct contact with the outer circumferential surface of the to- The artificial prosthesis 100 serves to fix the fractured bone and the to-be-bonded portion B2 so that the bone can be easily removed.

Here, when the fractured bone is defined as a first natural bone B1, the joint B2 is an artificial bone to be united to the first natural bone B1, or the first natural bone B1, The second natural bone having a shape corresponding to the shape of the fracture portion C of the first bone.

Specifically, the artificial prosthesis 100 (i.e., the internal fixation splint 200) is formed so as to surround the fractured portion C of the first natural bone B1 fractured and the peripheral portion of the first natural bone B1 to be joined to the first natural bone B1 At least one elongate member 210 fixed around the joint B2 and at least one elongate member 210 coupled to the first natural bone B1 and the to- A connecting member 220 connecting the elongate members 210 in the circumferential direction of the first natural bone B1 and the to-be-connected portion B2 when the elongate member 210 has a plurality of elongate members 210, .

According to the present invention, the elongated member 210 is formed on the outer surface of the first natural bone B1 and the outer surface of the to-be-bonded portion B2, on the basis of the thickness direction And an inner side surface 211 in which the bony union process proceeds and is fixed. The elongated member 210 has a main body 210a forming an outer shape of the elongated member 210 and at least a part of the surface of the main body 210a And a body fusion surface part (300).

Herein, for example, when the part B2 to be joined is an artificial bone, the body fusion surface part 300 is formed on the inner surface 211 of the elongate member 210, That is, the outer circumferential surface of the first natural bone B1).

However, when the area B2 is the second natural bone (for example, the natural bone that was in contact with the first natural bone B1 before fracture, or the natural bone obtained from other parts of the patient) The body fusion surface portion 300 is further provided at a portion of the inner side surface 211 of the elongate member 210 in contact with the second natural bone (i.e., the outer peripheral surface of the second natural bone) desirable.

At this time, the main body part 210a and the body fusion surface part 300 may be formed separately. However, the present invention is not limited thereto, and the body 210a and the body fusion surface portion 300 may be integrally formed by a single process.

The body fusion surface portion 300 has a porous surface structure made up of a plurality of fine grooves 310. The body fusion body surface portion 300 can significantly increase the surface area and bone fusion surface area of new bone cells have. A detailed description of the human body fusion surface portion 300 will be described in more detail with reference to FIG. 4 to FIG.

3 is a schematic perspective view and partially enlarged vertical sectional view of an artificial prosthesis 100 according to another embodiment of the present invention.

3, an artificial prosthesis 100 according to another embodiment of the present invention is an artificial bone, which is an example of an artificial prosthesis 100. The artificial bone 100 includes a first joint unit (not shown) 102 and a second union unit 103 and a support member 104 connecting the first union unit 102 and the second union unit 103 to each other.

Herein, at least one of the first union portion 102 and the second union portion 103 has a bony union portion, which is formed by the first bony union portion 102 and / or the second union portion 103, And a body unfused surface portion 300 provided on a surface of the body portion 101. The body portion 101 includes a body portion 101,

At this time, the body portion and the body unified surface portion 300 may be formed by separate processes. However, the present invention is not limited thereto, and the body portion and the body fusion surface portion 300 may be integrally formed by a single process.

The unfused surface portion 300 has a porous surface structure composed of a plurality of fine grooves 310, and the porous surface structure covers the entire outer surface of the body portion or covers a certain area or more. Therefore, the body fusion surface portion 300 can remarkably increase the surface area of the new bone cells to be produced and the union area. A detailed description of the human body fusion surface portion 300 will be described in more detail with reference to FIG. 4 to FIG.

Although only the artificial bone is shown in FIG. 3, the artificial prosthesis 100 according to a further embodiment may be a vertebrae cage inserted in place of a vertebra bone. In this case, the first union part 102 and the second union part (103) corresponds to the upper surface and the lower surface of the intervertebral cage, the upper surface and the lower surface of the intervertebral cage also form a contour of the cage, and a body union surface portion (300).

Preferably, the prostheses 100 described above in FIGS. 1-3 are made of a biocompatible metal (e.g., titanium, titanium alloy, chromium alloy, etc.), a biocompatible polymer (e.g., PEEK or PAEK) ≪ / RTI >

Preferably, the body fusion surface portion 300 is surface-treated with a bone cell inducing substance or a bone cell stimulating substance.

Hereinafter, referring to the drawings, the unfused surface portion 300 will be described in more detail.

4 is a partially enlarged vertical cross-sectional view of an unfused surface portion 300 according to an embodiment of the present invention, and FIG. 5 is a partially enlarged vertical sectional view of an unfused surface portion 300 according to an embodiment of the present invention. 6 is a schematic partial enlarged vertical cross-sectional view of an unfused surface portion 300 according to a second further embodiment of Fig. 4, and Fig. 7 is a schematic enlarged longitudinal sectional view of an approximate FIG. 8 is a partially enlarged longitudinal sectional view of the unfused surface portion 300 according to the third additional embodiment of FIG. 4, FIG. 9 is a partially enlarged vertical sectional view of the unfused surface portion 300 according to the fourth additional embodiment of FIG. 9 is a schematic partial enlarged vertical cross-sectional view of the surface portion 300, Fig. 10 is a schematic partial enlarged plan view of Fig. 9, Fig. 11 is a schematic enlarged plan view of the modified embodiment of Fig. 9, FIG. 12B is a cross-sectional view of the unfused surface portion according to a further embodiment of the present invention. Fig.

As shown in FIGS. 4 and 7, the unfused surface portion 300 has a plurality of fine grooves 310 and has a porous surface structure. The natural bone of the human body (for example, (E.g., a surface and / or a lower surface, or a fractured portion of a fractured natural bone (C), etc.).

Each of the fine grooves 310 includes an inflow opening 311 and a cell filling portion 313 communicating with the inflow opening 311 at a lower portion of the inflow opening 311 312).

The inflow opening 311 is an inlet through which new bone cells or bone tissue produced and / or grown from the natural bone can be introduced into the fine grooves 310, (I.e., new bone cells or bone tissue) flowing through the inlet opening 311 and forming a space for filling and growing the new body cells.

Preferably, the inlet opening 311 may have a diameter of 0.5 mm to 3 mm.

At least a part of the cell filling portion 312 is provided with a reverse gradient side portion 313 formed in the thickness direction of the inside of the body fusion surface portion 300.

At this time, the backward gradient side portion 313 is a portion of the side surface of the cell filling portion 312 that gradually increases in the distance between the inner side surfaces 312a of the cell filling portion 312 toward the inner thickness direction And the cross-sectional width W of the cell filling portion 312 gradually increases).

The backward gradient side portion 313 is formed such that a transverse sectional area of a portion (or a height) where the backward gradient side portion 313 is located in the cell filling portion 312 is larger than a transverse sectional area of the inflow opening 311 do.

As shown in the drawing, the longitudinal section of the backward gradient side part 313 has a convex curved shape, and the longitudinal section of the backward gradient side part 313 has a cross section of the cell filling part 312 And a pair of convex curved shapes facing each other on the inner side surface 312a of the inner side surface 312a.

Although not shown in the drawings, in a variant embodiment, the longitudinal profile of the backward gradient side portion 313 may be a pair of opposing linear shapes (i.e., a reverse tapered shape), or a pair of opposed, Lt; / RTI >

As shown in the figure, the longitudinal end face of the cell filling portion 312 having the backward gradient side portion 313 may have a pot shape formed in the thickness direction inside from the inlet opening 311 as a whole. At this time, the upper portion of the outermost width (W) portion (or height) of the jar-like cell filling portion 312 forms the backward gradient side portion 313.

Although not shown in the drawing, in a modified embodiment, the cell filling portion 312 has a flat plane portion at the lowermost portion of the backward gradient side portion 313, so that the cell filling portion 312 has a longitudinal sectional shape having the same or similar shape as the overall dovetail joint .

In this way, since the unfused surface portion 300 includes the fine grooves 310, it is possible to remarkably improve the surface area of the union between the natural bones of the human body to which the prosthesis 100 and the prosthesis 100 are jointed, As a result, the bony union force and / or the fixation force between the prosthesis 100 and the natural bone can be remarkably improved. Since the body fusion surface portion 300 includes the reverse gradient side portion 313, when the tensile force acts on the joint portion of the prosthetic prosthesis 100 and the natural bone, the body cavity fusion surface portion 300 is newly generated and filled in the cell filling portion 312 Since the backward gradient side portion 313 performs a hooking function with respect to new bone cells or bone tissue after solidification, the bone-joining strength and / or fixation force can be remarkably improved.

5 and 7, the cell filling portion 312 of the unfused surface portion 300 according to the first additional embodiment has a plurality of the smallest projecting portions 315 on the inner side surface 312a .

It is preferable that the microscopic convex portion 315 is formed by a blasting process. The blasting process may be, for example, a sand blasting process. Of course, this is an example, and the present invention is not limited thereto, and any process can be applied as long as it is capable of forming the minute convex portions 315.

By forming the extreme tapered portion 315 on the inner surface 312a of the cell filling portion 312, the surface area of union of the natural bone of the human body to which the prosthesis 100 and the prosthesis 100 are jointed Can be increased.

6 and 7, the unfused surface portion 300 according to the second additional embodiment is formed such that the outermost width W of the cell filling portion 312 is greater than the depth of the cell filling portion 312 (t). That is, the cell filling portion 312 of the unfused surface portion 300 according to the present embodiment may have an oval-shaped vertical cross-sectional shape, which is a longitudinal direction in total.

According to this embodiment, since the backward gradient side part 313 can be formed to be longer and wider, a wider jaw area can be secured for new bone cells or bone tissue filled in the cell filling part 312, It is possible to further improve the bony union force and / or fixation force between the prosthesis 100 and the natural bone.

8, the fine grooves 310 (or the cell filling portions 312) of the unfused surface portion 300 according to the third additional embodiment are formed by one fine groove 310 and one fine The pair of fine grooves 310 and the pair of fine grooves 310 constitute one pair of the adjacent fine grooves adjacent to the grooves 310. The pair of fine grooves 310 and the other fine grooves 310 form a cell filling portion 312, Are communicated with each other. That is, as shown in FIG. 8, the unfused surface portion 300 is configured such that two fine grooves 310 are communicated with each other. Of course, by applying this, the unfused surface portion 300 may be configured so that three or more fine grooves 310 communicate with each other.

9, the fine grooves 310 (or the cell filling portions 312) of the unfused surface portion 300 according to the third additional embodiment are formed as a whole by the cell filling of one fine groove 310 (312) of the micro groove (310) adjacent to the one micro groove (310).

That is, as shown in FIG. 10, the cell filling parts 312 of the plurality of fine grooves 310 communicate with each other in the row direction, so that new bone cells or bone tissues filled in the cell filling part 312 And may be connected to each other through a communicating portion of the filling portion 312 in a chain manner.

11, the cell filling portions 312 of the plurality of fine grooves 310 communicate with each other in the row direction and the column direction, and the cell filling portion 312 May be connected to each other through a communication part of the cell filling part 312 in a mesh manner.

The cell filling part 312 of the one fine groove 310 and the cell filling part 312 of the other fine groove 310 may be formed in the same manner as the cell filling part 312 of the one fine groove 310, It is preferable to communicate at the outermost width portions of the respective backward gradient side portions 313.

In this way, by connecting the cell filling portion 312 at least partially or wholly, it is possible not only to form the fine grooves 310 and the backward gradient side portion 313 in a larger area in the body fusion surface portion 300, New bone cells or bone tissues in the secondary fine groove 310 are connected to each other inside the cell filling portion 312 to further increase the bone fusion bonding force and / or fixation force between the prosthetic prosthesis 100 and the natural bone . 9 and the human body fusion surface portion 300 of FIG. 10, rather than the human body fusion surface portion 300 of FIG. 9, than the human fusion surface portion 300 of FIG. And has a bony union and / or fixation force between the large prosthesis 100 and the natural bone.

Further, as a further embodiment, as shown in Figs. 12A and 12B, it is preferable that the bony union inducing material is filled in the cell filling part of the unfused surface part by a predetermined volume.

The bone union inducing material is a substance that promotes and / or induces the formation of bone tissue or osteocytes between an artificial prosthesis and a natural bone of a human body after the artificial prosthesis is placed in the human body. The bone union inducing material may be one or more selected from the group consisting of, for example, titanium, hydroxyapatite (HA), beta -triccium phosphate, Bone Morphogenetic Protein (BMP), and Demineralized Bone Matrix It is composed of at least one substance. The bone union material is filled into the cell filling part in a powder state or a gel state.

Preferably, the predetermined volume of the bony unification inducing material is determined according to the total volume of the cell filling portion and / or the diameter of the inlet opening of the cell filling portion.

13 to 15 are schematic views of an artificial prosthesis 400 according to a modified embodiment of the present invention.

13 to 15, an artificial prosthesis 400 according to a modified embodiment of the present invention includes a first bending unit 410 and a second bending unit 420 provided at both ends to be fused to natural bones, Wow; And a support member 430 connecting the first union unit 410 and the second union unit 420.

At this time, the support member 430 is formed of a hollow member.

In particular, the support member 430 may be formed of a double hollow member. The support member 430 may include a first hollow member 431 and a second hollow member 432 surrounding the outer circumferential surface of the first hollow member 431.

At this time, the first hollow member 431 and the second hollow member 432 are made of different biocompatible materials. For example, the first hollow member 431 may be formed of ceramic, and the second hollow member 432 may be formed of a biocompatible polymer. Of course, the first hollow member 431 may be made of a biocompatible polymer and the second hollow member 432 may be made of ceramic.

As shown in FIG. 15, the hollow member 430 has a plurality of perforations 430a so as to have a network structure.

Also in this case, the second hollow member 432, or the first hollow member 431 and the second hollow member 432 have a plurality of perforations 430a so as to have a mesh structure. That is, only the second hollow member 432 located on the outer side surface may have a mesh structure, or both the first hollow member 431 and the second hollow member 432 may have a mesh structure.

In addition, the first union unit 410, the second union unit 420, and the support member 430 may be integrally formed.

In a further embodiment, the first union portion, the second union portion, and the first hollow member are integrally formed, and the second hollow member is formed so that the first union portion and the second union portion support each other And may be coupled to the first support member, the first union unit, and the second union unit.

1 to 12B, the first union portion 410 and the second union portion 420 include a body union surface portion 300 provided to cover the entire outer surface, The surface portion 300 has a porous surface structure composed of a plurality of fine grooves.

Specifically, each of the fine grooves has an inflow opening formed outside the unfused surface portion, a space communicating with the inflow opening, formed in an inner thickness direction of the unfused surface portion, And an inner surface of the cell filling portion includes at least a part of a reverse gradient side surface.

Preferably, the cell filling portion may have a very fine uneven portion on the inner side.

According to the present invention, since the porous surface structure is provided on the surface of the prosthesis, it is possible to remarkably improve the surface area of bone fusion between the natural bone of the human body to which the prosthesis and the prosthesis are jointed, It is possible to remarkably improve the bone fusion bonding force and / or fixation force between the bones.

Further, according to the present invention, by providing the surface structure of the prosthesis with a reverse gradient side portion, the upper portion of the fine groove (that is, the upper portion of the reverse gradient side portion of the body fusion surface portion) Or the bone tissue, it is possible to further improve the bone-joining strength between the surface of the prosthesis and the bone formation and / or the natural bone bony union, and as a result, the tensile load applied to the artificial prosthesis and the natural bone And can have a further improved union and / or clamping force.

In addition, since the present invention is entirely hollow, the amount of expensive biocompatible material can be significantly reduced, and manufacturing cost can be significantly reduced.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, . ≪ / RTI > Accordingly, such modifications are deemed to be within the scope of the present invention, and the scope of the present invention should be determined by the following claims.

100: artificial prosthesis
200: Internal fixation splint
300: human body fusion surface portion
310: fine groove
311: inlet opening
312: cell filling part
313: reverse gradient side portion
315: Do not push

Claims (11)

A first bone union part and a second bone union part provided at both ends and fused to natural bone;
And a support member connecting the first union unit and the second union unit,
Wherein the support member comprises a hollow member. The method according to claim 1,
Wherein the support member includes a first hollow member and a second hollow member surrounding the outer circumferential surface of the first hollow member. 3. The method of claim 2,
Wherein the first hollow member and the second hollow member are constructed of different biocompatible materials. The method of claim 3,
Wherein said biocompatible material is one of a ceramic, a biocompatible metal, and a biocompatible polymer. The method according to claim 1,
Wherein the hollow member has a plurality of perforations so as to have a mesh structure. 3. The method of claim 2,
Wherein the second hollow member or the first hollow member and the second hollow member have a plurality of perforations so as to have a mesh structure. The method according to claim 1,
Wherein the first union portion, the second union portion, and the support member are integrally formed. 3. The method of claim 2,
The first union portion, the second union portion, and the first hollow member are integrally formed,
And the second hollow member is coupled to the first supporting member, the first union unit, and the second union unit such that the first union unit and the second union unit support each other. The method according to claim 1,
Wherein the first union portion and the second union portion include a body union surface portion covering the entire outer surface,
Wherein the body unfused surface portion has a porous surface structure composed of a plurality of fine grooves. 10. The method of claim 9,
Wherein each of the fine grooves has:
An inflow opening formed on the outside of the human body fusion surface portion,
And a cell filling part communicating with the inflow opening and formed in an inner thickness direction of the unfused surface part and being a space in which human cells are grown and filled,
Wherein an inner surface of the cell filling portion includes at least a portion of a reverse gradient side surface. 11. The method of claim 10,
Wherein the cell filling portion has a very fine concave / convex portion on the inner side.

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