KR20160062532A - Spray apparatus comprising air and coating solution injection nozzle - Google Patents

Spray apparatus comprising air and coating solution injection nozzle Download PDF

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Publication number
KR20160062532A
KR20160062532A KR1020140165405A KR20140165405A KR20160062532A KR 20160062532 A KR20160062532 A KR 20160062532A KR 1020140165405 A KR1020140165405 A KR 1020140165405A KR 20140165405 A KR20140165405 A KR 20140165405A KR 20160062532 A KR20160062532 A KR 20160062532A
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South Korea
Prior art keywords
coating liquid
stent
nozzle
cleaning liquid
coating
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KR1020140165405A
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Korean (ko)
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최형준
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주식회사 노아닉스
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Priority to KR1020140165405A priority Critical patent/KR20160062532A/en
Publication of KR20160062532A publication Critical patent/KR20160062532A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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Abstract

The injection device for an ultrasonic stent coating for spraying a coating liquid onto a stent fixed by a stent transfer device according to the present invention and generating ultrasonic waves to coat the surface of the stent is supplied with a coating liquid containing a drug from a coating liquid supply part And a cleaning liquid spraying part for spraying and discharging the cleaning liquid from an air discharge part and a cleaning liquid supply part for generating ultrasonic waves in spraying the coating liquid and discharging the air supplied from the air supply part, A coating liquid spray nozzle for spraying the coating liquid toward the upper side of the stent while being spaced apart from the stent by a predetermined distance and a coating liquid spray nozzle for spraying the coating liquid from the coating liquid spray nozzle to the coating liquid spray nozzle, Wherein the air discharge portion includes a supply member An ultrasonic nozzle tip member for generating ultrasonic waves toward the stent at the time of spraying the coating liquid and a through hole formed at the center of the ultrasonic nozzle tip member and for supplying compressed air supplied through an air supply member connected to the air supply unit to the stent And the air discharge nozzle discharges compressed air discharged through the air discharge nozzle to focus the coating liquid injected from the coating liquid injection nozzle with the stent.

Description

TECHNICAL FIELD [0001] The present invention relates to an injection device for coating an ultrasonic stent with an air spray nozzle and a coating liquid spray nozzle,

BACKGROUND OF THE INVENTION 1. Field of the Invention [0001] The present invention relates to an injection device for an ultrasonic stent coating, and more particularly, to a medical device used for normalizing the flow of blood or body fluids by inserting the injection device into a relevant part such as a blood vessel, a gastrointestinal tract, The present invention relates to an injection apparatus for an ultrasonic stent coating having an air injection nozzle and a coating liquid injection nozzle which are configured such that a coating liquid is not scattered to a coating apparatus in coating a surface of a stent.

Generally, a stent is developed for the treatment of coronary artery. When a blood or body fluid does not flow smoothly in a blood vessel, a gastrointestinal tract, or a bile duct due to a malignant or benign disease, Is a cylindrical medical material used to normalize the flow of blood or body fluids by inserting it into a closed or clogged area.

More specifically, coronary artery stenosis, such as arteriosclerosis, is generally treated using percutaneous transluminal coronary angioplasty, which was performed in 1977 by Gruentzig < RTI ID = 0.0 > ) Has been inserted into a balloon-shaped device called a catheter, and has been actively practiced worldwide since its first operation.

However, conventional catheter-based coronary angioplasty has been associated with acute closure and restenosis during or after the procedure.

Therefore, in order to reduce the problems of restenosis and the like, there have been conventionally used atherectomy, rotabulation, transluminal extraction catheter, excimer laser coronary angioplasty and stent, New methods such as the insertion of a magnetic field have been studied.

However, in these methods, there is no way to reliably relieve the restenosis phenomenon other than the procedure of widening and maintaining the physically restenosed region by inserting the stent.

Even if the stent is used to maintain the extension after percutaneous coronary angioplasty (PTCA), there is a problem that restenosis occurs at a rate of about 20 to 30%, although the restenosis rate is low, as compared with the case of only PTCA.

In addition, for example, in the treatment of a patient suffering from an esophageal cancer, when expanding the narrowed esophageal region by a physical force in accordance with the proliferation of the cancer and allowing the patient to ingest the food, May be performed.

However, conventional metal stents have a problem in that as the size of the tumor increases with the lapse of time, the invasion of the cancer continues between the gaps of the stent metal mesh, resulting in a restenosis phenomenon in which the esophageal lumen narrows again.

In addition, since the intestinal thickening is the main cause of restenosis after insertion of the stent, recently, a drug capable of inhibiting the migration and proliferation of vascular smooth muscle cells, which is a direct cause of intimal thickening, is coated on the stent, A drug release type stent for preventing restenosis by releasing a drug has been developed.

Examples of the above agents include taxol (Paclitaxel), mitomycin C, adriamycin, genistein, tyrphostin, cytochalasin, ), Sirolimus (Rapamycin), and the like. Coating of such a drug is performed by coating a part or all of the stent so that a coating solution in which the drug and the biocompatible polymer are dissolved in the solvent is present on the surface of the stent .

The conventional stent coating method includes, for example, an immersion method in which a stent is immersed in a coating solution, followed by drying, and a spray method in which a coating solution is sprayed.

Here, in the dipping method, there is a case where a web (coating between struts) or a bridge is generated in the space portion of the stent by immersion, and in addition to the possibility that the web or bridge affects the mechanical function of the stent, If a part of the web or bridge is destroyed or peeled and flows to peripheral blood vessels after mounting, it may cause blood circulation disorder, which is not preferable.

On the other hand, the spray method can form a coating layer by spraying a coating liquid onto the outer and / or inner circumferential surface of the stent while rotating the stent and / or moving the spray nozzle, for example, as shown in Japanese Patent No. 10-1374073.

However, as in the prior art, the spray method is more liable to waste the coating liquid than the amount of the sprayed coating liquid adhered to the stent, and in particular, when the scattered coating liquid is adsorbed to the coating apparatus, There arises a problem that the operation is difficult or the management cost is increased.

SUMMARY OF THE INVENTION The present invention has been conceived in order to solve the above-mentioned problems, and it is an object of the present invention to provide a stent with a coating solution uniformly sprayed to a stent, The present invention also provides an injection apparatus for an ultrasound stent coating having an air injection nozzle and a coating liquid injection nozzle which can be used for a stent coating.

However, the object of the present invention is not limited to the above-mentioned objects, and other objects not mentioned can be clearly understood by those skilled in the art from the following description.

In order to achieve the above object, an ultrasonic stent-coating spraying apparatus for spraying a coating liquid onto a stent fixed in position by a stent transfer device according to an embodiment of the present invention and generating ultrasonic waves to coat the surface of the stent, And a cleaning liquid supply unit for supplying the cleaning liquid from the air discharge unit and the cleaning liquid supply unit for generating the ultrasonic waves when spraying the coating liquid and discharging the compressed air supplied from the air supply unit, Wherein the coating liquid injecting unit includes a coating liquid spray nozzle for spraying the coating liquid toward the upper side of the stent while being spaced apart from the stent by a predetermined distance and a coating liquid spray unit for connecting the coating liquid spray nozzle and the coating liquid supply unit, Wherein the coating liquid is supplied to the coating liquid injection nozzle Wherein the air discharging portion includes an ultrasonic nozzle tip member for generating an ultrasonic wave toward the stent when spraying the coating liquid and a through hole formed at the center of the ultrasonic nozzle tip member, And an air discharge nozzle for discharging the compressed air supplied through the member toward the stent. The compressed air discharged through the air discharge nozzle focuses the coating liquid injected from the coating liquid spray nozzle with the stent do.

According to another aspect of the present invention, there is provided an injection apparatus for coating an ultrasonic stent, wherein the coating liquid injection nozzle is disposed at a predetermined angle with respect to the ground.

According to another aspect of the present invention, there is provided an injection apparatus for coating an ultrasonic stent, the apparatus including a cleaning liquid injection unit for spraying a cleaning liquid supplied from a cleaning liquid supply unit, the cleaning liquid injection unit being disposed at a position facing the coating liquid injection nozzle, A cleaning liquid spray nozzle for spraying the cleaning liquid toward the coating liquid spray nozzle and the ultrasonic nozzle tip member, and a cleaning liquid supply part for supplying the cleaning liquid to the cleaning liquid spray nozzle, And the cleaning liquid supply member supplying the cleaning liquid to the cleaning liquid supply unit.

According to another aspect of the present invention, there is provided an injection apparatus for coating an ultrasonic stent, wherein the coating liquid spray nozzle is disposed closer to the ultrasonic nozzle tip member than the cleaning liquid spray nozzle.

In addition, the ultrasonic stent-coating spraying apparatus according to the present invention may include a coating liquid spray nozzle, an ultrasonic nozzle tip member, and a vertical transfer unit for vertically moving the cleaning liquid spray nozzle. The vertical transfer unit may include a coating liquid spray nozzle, A support member to which the nozzle tip member and the cleaning liquid jetting nozzle are mounted; a pair of the support member, which is disposed between the upper frame and the lower frame in a direction perpendicular to the paper surface and on which the support member is mounted, A rotary member which is formed in a cylindrical shape and has a thread on an outer circumferential surface of a lower end of the lower end thereof and which is disposed between the guide bars and rotatably supports the support member in a vertical direction, And a knob member for rotating the rotary member All.

According to the injection apparatus for coating an ultrasonic stent with the air injection nozzle and the coating liquid injection nozzle according to the present invention, the coating liquid containing the medicament is precisely sprayed toward the stent in a predetermined direction by using air injected at high pressure during the ultrasonic coating There is an advantage that the coating liquid can be uniformly coated on the stent.

1 is a perspective view schematically showing a stent coating system to which an injection apparatus for coating an ultrasonic stent according to the present invention is applied.
2 is a front view showing an injection apparatus for an ultrasonic stent coating having an air injection nozzle and a coating liquid injection nozzle according to an embodiment of the present invention.
3 is a partially enlarged view showing a jetting portion including an air jetting nozzle and a coating liquid jetting nozzle according to the present invention.
FIG. 4 is an exemplary view illustrating a process of coating a stent through an injection device for coating an ultrasonic stent according to the present invention.
FIG. 5 is an exemplary view illustrating a process of cleaning a nozzle through an injection device for coating an ultrasonic stent according to the present invention.
FIG. 6 is a perspective view schematically showing a stent delivery apparatus constituting the stent coating system of the present invention. FIG.
7 is a cross-sectional view showing the configuration of the stent delivery device of Fig.
Fig. 8 is an exemplary view showing a joint state of a joint portion and an LM driver in the stent delivery device of Fig. 6; Fig.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a detailed description of preferred embodiments of the present invention will be given with reference to the accompanying drawings. In the following description of the present invention, detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear.

Embodiments in accordance with the concepts of the present invention can make various changes and have various forms, so that specific embodiments are illustrated in the drawings and described in detail in this specification or application. It is to be understood, however, that it is not intended to limit the embodiments according to the concepts of the present invention to the particular forms of disclosure, but includes all modifications, equivalents, and alternatives falling within the spirit and scope of the invention.

It is to be understood that when an element is referred to as being "connected" or "connected" to another element, it may be directly connected or connected to the other element, . On the other hand, when an element is referred to as being "directly connected" or "directly connected" to another element, it should be understood that there are no other elements in between. Other expressions that describe the relationship between components, such as "between" and "between" or "neighboring to" and "directly adjacent to" should be interpreted as well.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The singular expressions include plural expressions unless the context clearly dictates otherwise. In this specification, the terms "comprises ",or" having ", or the like, specify that there is a stated feature, number, step, operation, , Steps, operations, components, parts, or combinations thereof, as a matter of principle.

FIG. 1 is a perspective view schematically showing a stent coating system to which an injection apparatus for coating an ultrasonic stent according to the present invention is applied. FIG. 2 is a perspective view of a stent coating system for applying an ultrasonic stent coating apparatus according to an embodiment of the present invention. FIG. 3 is a partially enlarged view showing a jetting portion including an air jetting nozzle and a coating liquid jetting nozzle according to the present invention. FIG.

Referring to the drawings, a stent coating system 10 according to the present invention includes a stent 1 for injecting a coating solution containing a drug, generating ultrasonic waves, and applying ultrasonic stent coating for coating the surface of the stent 1 And a stent delivery device 200 for moving the position of the device 100 and the stent 1.

The injector 100 for coating an ultrasonic stent may include a coating liquid spraying unit 110, an air discharging unit 120, a cleaning liquid spraying unit 130, and a vertical transfer unit 140.

The coating liquid spraying unit 110 is for spraying the coating liquid containing the medicament from the coating liquid supply unit 113 and may include a coating liquid injection nozzle 111 and a coating liquid supply member 112.

The coating liquid spraying nozzle 111 is capable of spraying the coating liquid toward the upper side of the stent 1 while being spaced apart from the stent 1 by a predetermined distance and the coating liquid supplying member 112 is in the form of a tube for supplying a coating liquid, And may be connected between the injection nozzle 111 and the coating liquid supply part 113 to supply the coating liquid to the coating liquid injection nozzle 111.

The coating liquid spraying nozzle 111 may be disposed on one side of the front surface of the support member 141 constituting the vertical transfer unit 140 as shown in the figure. Further, the coating liquid spraying nozzle 111 may be arranged at an angle (for example, an angle of 10 to 30 degrees) with respect to the paper surface.

The medicament contained in the coating liquid 3 used in the injection apparatus 100 for the ultrasonic stent coating of the present invention is generally used. Examples of the medicament include taxol (paclitaxel), mitomycin C, adriamycin, genistein, Tyrosine, tyrphostin, cytochalasin, and sirolimus (rapamycin). In addition, various medicines may be used depending on the use.

An air discharge portion 120 for generating ultrasonic waves and discharging air supplied from the air supply portion 121, that is, compressed air, includes an ultrasonic nozzle tip member 122, an air discharge nozzle 124 and an air supply member 125 can do.

The ultrasonic nozzle tip member 122 may generate ultrasonic waves toward the stent 1 when the coating liquid is sprayed through the coating liquid spray nozzle 111. In particular, a through hole 123 may be formed at the center.

An air discharge nozzle 124 may be disposed in the through-hole 123. The air discharge nozzle 124 is disposed in a direction perpendicular to the paper surface so as to discharge the compressed air supplied through the air supply member 125 in the form of a tube connected to the air supply unit 121 toward the stent 1 .

The air discharge unit 120 includes an ultrasonic nozzle tip member 122 disposed at the front center of the support member 141 constituting the vertical transfer unit 140 and having an air discharge nozzle 124, May be disposed on the lower surface of the air discharge unit 120 so as to face the ground.

The cleaning liquid spraying unit 130 for spraying the cleaning liquid has a cleaning liquid spraying nozzle 131 disposed at a position facing the coating liquid spraying nozzle 111, that is, on the other side of the front surface of the supporting member 141, And a cleaning liquid supply member 132 connecting the cleaning liquid supply unit 133 for supplying the cleaning liquid and the cleaning liquid spray nozzle 131.

The cleaning liquid spray nozzle 131 discharges the cleaning liquid supplied from the cleaning liquid supply unit 133 through the cleaning liquid supply member 134 to the coating liquid spray nozzle 111 and the ultrasonic nozzle tip member 122 So that a cleaning operation such as removal of foreign matters can be performed.

Therefore, the cleaning liquid jetting nozzle 131 is positioned above the cleaning liquid jetting nozzle 131 so that the coating liquid jetting nozzle 111 can perform a preferable cleaning operation for the coating liquid jetting nozzle 111 and the ultrasonic nozzle tip member 122 May be configured to be disposed proximate the ultrasonic nozzle tip member (122).

The vertical transfer unit 140 includes a support member 141, a guide bar 142, a rotation member 140, and a rotation member 140. The vertical transfer unit 140 includes a coating liquid spray unit 110, an air discharge unit 120, A member 143 and a pull member 144, as shown in Fig.

The coating liquid spray nozzle 111, the ultrasonic nozzle tip member 122, and the cleaning liquid spray nozzle 131 may be mounted on the front surface of the support member 141. First and second through holes 142 and 142 may be formed on one side and the other side of the upper surface of the support member 141 in the vertical direction and a second through hole 143 may be formed in the center thereof.

A pair of guide bars 144 and 144 may be disposed in the first through holes 142 and 142 formed in the support member 141 in a direction perpendicular to the paper surface. The upper side of the guide bars 144 and 144 is fixed to the upper frame 150 and the lower side thereof is fixed to the lower frame 160. The support member 141 is vertically movable through the pair of guide bars 144 and 144 Can be guided.

In addition, the rotation member 145 may be disposed in the second through hole 143 formed between the pair of first through holes 142, 142. The rotary member 145 is cylindrical and may have a thread 146 formed on the outer peripheral surface of the lower end.

A knob member 147 is provided at the upper end of the rotary member 145 to rotate the rotary member 145.

Although not specifically shown, a thread may be formed on the inner circumferential surface of the second through hole 143 on which the rotary member 145 is mounted, to be coupled with the thread 146 of the rotary member 145.

The rotation member 145 is rotated by the rotation of the pull member 147 and the support member 141 can be vertically moved upward or downward along the thread 146 of the rotating member 145 to be rotated .

FIG. 4 is an exemplary view illustrating a process of coating a stent through an injection device for coating an ultrasonic stent according to the present invention. FIG. 5 is a view illustrating a process of cleaning a nozzle through an injection device for coating an ultrasonic stent, Fig.

Referring to the drawings, the compressed air 14 discharged through the air discharge nozzle 124 can focus the coating liquid 13 injected from the coating liquid injection nozzle 111 to the rotating stent 1.

That is, when the coating liquid 13 is injected in an upward direction of the stent 1, the surface of the stent 1 can be coated by being discharged into the stent 1 by discharging the compressed air 14.

Therefore, the sprayed coating liquid 13 can be concentrated only on the stent 1, and can be prevented from being scattered into air and wasted.

The coating liquid 13 which is not coated on the surface of the stent 1 can be collected in a separate coating liquid collection member 170 disposed under the stent 1 by the discharge direction of the compressed air 14 have.

5, the ultrasonic stent-coating spraying apparatus 100 according to the present invention includes a cleaning liquid spray nozzle 131 disposed at a position facing the coating liquid spray nozzle 111 to discharge the cleaning liquid 15 Cleaning of the coating liquid injection nozzle 111 and the ultrasonic nozzle tip member 122 can be performed.

Therefore, there is a feature that the clogging phenomenon of the nozzle due to the coating liquid 13 can be prevented in advance.

FIG. 6 is a perspective view schematically showing a stent delivery system constituting the stent coating system of the present invention, FIG. 7 is a cross-sectional view showing the structure of a stent delivery system, FIG. 8 is a view showing a state where the joint part and the LM drive part Fig.

Referring to the drawings, the stent delivery device 200 includes a stent fixing unit 210, a rotational power generating unit 220, a power transmitting unit 230, a joint unit 240, a LM (Linear Mortion) And a case part 160. [0033] FIG.

Particularly, the stent fixing unit 210, the rotational power generating unit 220, and the power transmitting unit 230 are accommodated in a case 160, which will be described later, in a state of being disposed on the upper side of the base plate 11, Mortion) driving unit 250 may be disposed on the lower side of the base plate 11.

The joint portion 240 may be disposed in the guide hole 12 formed in the base plate 11 in the longitudinal direction.

In addition, the injection device 200 for ultrasonic stent coating may be disposed on the upper surface of the base plate 11.

One end of the stent fixing part 210 is provided with a fixing pin 211 and the stent 1 can be inserted and fixed to the fixing pin 211. [

The rotational power generating unit 220 generates rotational power, and may be a motor driven by a predetermined speed and direction, for example, supplied with power.

The power transmitting portion 230 connects the other end of the stent fixing portion 210 and the rotation power generating portion 220. The power transmitting portion 230 and the stent fixing portion 210 are connected to each other by a clamp 231, Detachably coupled.

Therefore, the rotational power generated through the rotational power generating unit 220 can be transmitted to the power transmitting unit 230 and the stent fixing unit 210 to rotate the fixed stent 1.

The joint portion 240 is coupled to the lower portion of the rotary power generating portion 220 and the joint portion 240 coupled to the rotary power generating portion 220 is coupled to the LM (Linear Mortion) driving unit 250. [

Accordingly, the linear motion of the joint unit 240 mounted on the LM driver 250 allows the position of the rotating stent 1 to be linearly moved during the coating operation.

The stent delivery device 100 according to the present invention can be accommodated in the case 260. The case 260 has an opening 261 formed on one surface thereof facing the stent coating apparatus 200, The stent fixing part 210 having the stent 1 fixed through the opening part 261 can be protruded to the outside.

More specifically, the stent fixing unit 210 is linearly moved in the linear movement of the LM driver 250, and the stent fixing unit 210 is linearly moved through the opening 261, As shown in FIG.

Therefore, it is possible to prevent the scattered coating liquid from being adsorbed to other constituent parts of the stent transfer device 100 by the case 260 during the coating operation with respect to the stent 1.

In the present invention, the shape of the case is shown as a rectangle. However, if the coating liquid can be prevented from being adsorbed by the transfer device, the shape of the case can be variously changed.

The LM driver 250 that is capable of linearly moving the position of the stent 1 includes a power generating member 251 such as a motor that generates power by receiving power and a power generator 251 connected to the power generating member 251, And a LM (Linear Mortion) guide rails 253 and 253 disposed on both sides of the rotary member 252, respectively. The rotary member 252 performs a rotary motion with respect to the central axis in the longitudinal direction, have.

The rotary member 252 may have a cylindrical shape or a bar shape and may have a first thread 154 formed on an outer circumferential surface of the other end.

As shown in the drawing, the joint part 240 to be mounted on the LM driver 250 is formed with a through hole 241 at the bottom center, and LM guide rails 253 and 253 are formed on both sides of the through hole 241, The guide grooves 242 and 242 may be formed in the guide grooves 252 and 253, respectively.

A second screw thread 243 is formed on the inner peripheral surface of the through hole 241 so that the rotary member 252 can be inserted and disposed.

The second screw thread 243 formed on the inner circumferential surface of the through hole 241 when the rotary member 252 rotates with respect to the axis in a state where the rotary member 252 is inserted into the through hole 241, 154, the joint portion 240 can be moved in a linear direction.

Particularly, it is possible to guide the movement of the joint portion 240 through the guide grooves 242 and 242 mounted on the LM guide rails 253 and 253, respectively.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the appended claims. will be. Accordingly, the true scope of the present invention should be determined by the technical idea of the appended claims.

1: stent 10: stent coating system
100: Injection device for ultrasonic stent coating
110:
111: coating liquid spray nozzle 112: coating liquid supply member
113:
120:
121: air supply part 122: ultrasonic nozzle tip member
123: through hole 124: air discharging member
125: Air supply member
130: Cleaning liquid dispenser
131: Cleaning liquid spray nozzle 132: Cleaning liquid supply member
133: Cleaning liquid supply unit
140: Vertical transfer part
141: support member 142: first through hole
143: second through hole 144: guide bar
145: rotating member 146: threaded
147: Handle member
150: upper frame 160: lower frame
200: Stent delivery device

Claims (5)

1. An injection device for an ultrasound stent coating apparatus for spraying a coating liquid onto a stent fixed in position by a stent transfer device and generating ultrasonic waves to coat the surface of the stent,
A coating liquid dispensing part for dispensing a coating liquid containing a medicament from a coating liquid supply part and injecting the coating liquid;
An air discharge unit for generating ultrasonic waves when spraying the coating liquid and discharging compressed air supplied from the air supply unit; And
And a cleaning liquid spraying unit for spraying the cleaning liquid supplied from the cleaning liquid supply unit,
The coating liquid injector may include:
A coating liquid spray nozzle for spraying the coating liquid toward the upper side of the stent while being spaced apart from the stent by a predetermined distance; And
And a coating liquid supply member connected between the coating liquid spray nozzle and the coating liquid supply unit and supplying the coating liquid to the coating liquid spray nozzle,
The air discharge portion
An ultrasonic nozzle tip member for generating ultrasonic waves toward the stent when injecting the coating liquid; And
And an air discharge nozzle disposed in a through hole formed at the center of the ultrasonic nozzle tip member and discharging compressed air supplied through an air supply member connected to the air supply unit toward the stent,
Wherein the compressed air discharged through the air discharge nozzle focuses the coating liquid injected from the coating liquid injection nozzle with the stent.
The method according to claim 1,
Wherein the coating liquid spraying nozzle is disposed in a state of being inclined at a predetermined angle with respect to the ground surface.
The method according to claim 1,
Further comprising a cleaning liquid jetting section for jetting cleaning liquid supplied from the cleaning liquid supply section,
Wherein the cleaning liquid jetting unit comprises:
A cleaning liquid spray nozzle disposed at a position facing the coating liquid spray nozzle and spraying the cleaning liquid toward the coating liquid spray nozzle and the ultrasonic nozzle tip member; And
And a cleaning liquid supply member connected between the cleaning liquid supply unit for supplying the cleaning liquid and the cleaning liquid spray nozzle and supplying the cleaning liquid to the cleaning liquid spray nozzle. Spraying device.
The method of claim 3,
Wherein the coating liquid spray nozzle is disposed closer to the ultrasonic nozzle tip member than the cleaning liquid spray nozzle.
The method of claim 3,
And a vertical transfer unit for vertically moving the coating liquid spray nozzle, the ultrasonic nozzle tip member, and the cleaning liquid spray nozzle,
Wherein the vertical transfer unit comprises:
A support member to which the coating liquid spray nozzle, the ultrasonic nozzle tip member, and the cleaning liquid spray nozzle are mounted;
A pair of guide bars disposed between the upper frame and the lower frame in a direction perpendicular to the paper and mounted with the support members and guiding movement of the support members in the vertical direction;
A rotary member formed in a cylindrical shape and having a thread formed on an outer peripheral surface of a lower end from an upper end thereof and disposed between the guide bars to vertically transfer the support member by rotation; And
And a grip member mounted on an upper end of the rotating member to rotate the rotating member.
KR1020140165405A 2014-11-25 2014-11-25 Spray apparatus comprising air and coating solution injection nozzle KR20160062532A (en)

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