KR20160031946A - Closing and opening device for strip tube - Google Patents

Closing and opening device for strip tube Download PDF

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Publication number
KR20160031946A
KR20160031946A KR1020150060611A KR20150060611A KR20160031946A KR 20160031946 A KR20160031946 A KR 20160031946A KR 1020150060611 A KR1020150060611 A KR 1020150060611A KR 20150060611 A KR20150060611 A KR 20150060611A KR 20160031946 A KR20160031946 A KR 20160031946A
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KR
South Korea
Prior art keywords
tube
strip
cover plate
strip tube
arc
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KR1020150060611A
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Korean (ko)
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KR101880575B1 (en
Inventor
웬-호 장
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(주)한국케트
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/24—Apparatus for enzymology or microbiology tube or bottle type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/043—Hinged closures

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)

Abstract

The present invention includes an upper cover plate, a clamp plate, and a lower cover plate having a plurality of strips through which the gap of the strip tube can pass; When the strip tube is disposed in the reaction tray, the strips pass through the gap of the strip tube, respectively, and the tube cover of the strip tube is separated from the tube body by the force applied to the handle, There is provided a strip tube opening / closing device for preventing a tube cover of a separated strip tube from being elastically separated from an opening, thereby preventing an error in a direction in which the tube cover is covered with the tube body again. In addition, the edge of the clamp plate may significantly shrink toward the inside of the upper cover plate and the lower cover plate to reduce the downward pressure when the cover of the convex-cover type PCR strip tube is closed and used.

Description

[0001] CLOSING AND OPENING DEVICE FOR STRIP TUBE [0002]

The present invention relates to a strip tube opening and closing apparatus, and more particularly, to a strip tube opening and closing apparatus having a plurality of strips through which a gap of a strip tube can pass at one end of a lower cover plate, To a strip tube opening / closing device.

The sample loading mechanism required for a typical polymerase chain reaction (PCR) is generally divided into a single tube, an 8 × 1 strip tube, a 12 × 1 strip tube, and an 8 × 12 well reaction tray. Each strip tube, whether an 8 * 1 strip tube or a 12 * 1 strip tube, has a tube body and a tube cover, and the tube body contains a bio-nucleic acid genetic material, enzyme and material For example, DNA, RNA, and the like.

When using both conventional 8-strip and 12-strip PCR reaction tubes, you must release the tube cover from the tube body with your finger, place the sample liquid into the tube body, and then close the tube cover with your fingers. However, when the tube cover is opened after the reaction is completed, if the applied force is too large, the tube body is shaken and liquid in the tube body is repelled and enters the other tube body to cross-contaminate the liquid in the tube body, .

An object of the present invention is to provide a method of separating a tube cover and a tube body of a strip tube by a force applied to a handle and having a plurality of strips with one end of the lower cover plate passing through a gap of the strip tube, And to provide a strip tube opening / closing device with reduced size.

SUMMARY OF THE INVENTION It is an object of the present invention to provide a strip tube opening and closing apparatus in which an upper cover plate, a clamp plate and a lower cover plate are made of a stainless steel material so as to be convenient for disinfection and reuse.

It is an object of the present invention to provide a strip tube having a first concave groove having a width slightly larger than a width of a tube cover of the strip tube and a tube cover of the strip tube and a tube body To provide a strip tube opening / closing device.

The present invention is characterized in that the upper cover plate having the first arched hole at the first end, the clamp plate having the second arc-shaped hole at the portion corresponding to the first arc-shaped hole, A plurality of strips coupled to the plate and below the clamp plate and having a third arcuate hole at a portion of the first end corresponding to the arcuate hole and a second end capable of passing through the gap of the strip tube; , The first arc-shaped hole, the second arc-shaped hole and the third arc-shaped hole include a lower cover plate capable of forming a handle; A strip tube opening / closing device which can separate the tube cover of the strip tube and the tube body by a force applied to the handle, respectively, when the strip tube is disposed in the reaction tray, Lt; / RTI >

Preferably, the upper cover plate, the clamp plate, and the lower cover plate are made of stainless steel to facilitate disinfection and reuse.

Wherein the first end of the upper cover plate and the lower cover plate are of the same length and arc shape and the first end of the clamp plate is relatively inwardly tapered relative to the length of the upper cover plate and the lower cover plate, Preferably, the first end portions of the upper cover plate, the clamp plate, and the lower cover plate form a first concave groove.

The width of the first concave groove is slightly larger than the width of the tube cover of the strip tube so that the tube cover of the strip tube and the tube body can be coupled by the force applied to the first concave groove.

It is preferable that the number of the plurality of strips is nine, and a gap is provided between each of the strips.

And the second end of the clamp plate may further include a plurality of second concave grooves having a number of eight that can accommodate the tube body of the strip tube at a portion corresponding to the interval of the plurality of strips.

Wherein the second end of the lower cover plate further comprises a plurality of circular holes having a number of eight in a portion corresponding to the interval of the plurality of strips, the diameter of the circular hole being slightly larger than the tube cover of the strip tube, It is preferable that a hole is disposed above the tube cover of the strip tube and a force is applied so that the tube cover and the tube body can be engaged.

The present invention is characterized in that the upper cover plate having the first arched hole at the first end, the clamp plate having the second arc-shaped hole at the portion corresponding to the first arc-shaped hole, A plurality of strips coupled to the plate and below the clamp plate and having a third arcuate hole at a portion of the first end corresponding to the arcuate hole and a second end capable of passing through the gap of the strip tube; , The first arc-shaped hole, the second arc-shaped hole and the third arc-shaped hole include a lower cover plate capable of forming a handle; Wherein the strips pass through gaps of the strip tubes when the strip tubes are disposed in the reaction tray and are capable of separating the tube covers of the strip tubes from the tube bodies by a force applied to the grips, Device.

1 is an exploded view of a strip tube opening and closing apparatus according to a preferred embodiment of the present invention.
2 is an assembled view of a strip tube opening and closing apparatus according to a preferred embodiment of the present invention.
FIG. 3 is a schematic view showing a state where a tube cover of a strip tube is opened in a strip tube opening and closing apparatus according to a preferred embodiment of the present invention.
FIG. 4 is a schematic view showing a state in which a tube cover of a strip tube is closed in a strip tube opening and closing apparatus according to a preferred embodiment of the present invention.
5 is a schematic view showing a state in which a tube cover of a strip tube is closed in a strip tube opening and closing apparatus according to another preferred embodiment of the present invention.

It will be understood by those skilled in the art that the present invention may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, It is provided to let you know.

In addition, the structure or configuration of any one of the embodiments described below may be applied to or replaced with the structure or configuration of another embodiment as required by a typical technician, or the configuration may be deleted or a different configuration may be added. It is self-evident.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 is an exploded view of a strip tube opening / closing apparatus according to a preferred embodiment of the present invention, FIG. 2 is an assembled view of a strip tube opening and closing apparatus according to a preferred embodiment of the present invention, FIG. 3 FIG. 4 is a schematic view illustrating a state in which a tube cover of a strip tube is closed in a strip tube opening / closing device according to a preferred embodiment of the present invention. FIG. FIG. 5 is a schematic view showing a state in which a tube cover of a strip tube is closed in a strip tube opening / closing device according to another preferred embodiment of the present invention. FIG.

 As shown in the drawing, the strip tube opening / closing apparatus according to the present invention includes an upper cover plate 10, a clamp plate 20 and a lower cover plate 30 assembled.

The apparatus for opening and closing a strip tube according to the present invention may be applied to a strip tube 50, and the strip tube 50 may be, for example, a convex cover type polymerase chain reaction (PCR) Do not. The capacity of each tube body is 0.2 ml, and the strip tube 50 is made of, for example, but not limited to, plastic material, and has eight tube bodies 52 and eight tube covers 53, Between each tube body 52 and the tube cover 53 are interconnected and a gap 54 is provided between each tube body 52.

The upper cover plate 10 may be made of stainless steel for convenience of disinfection and reuse, and the first end may have a first arcuate hole 11, but the present invention is not limited thereto.

The clamp plate 20 is made of stainless steel for easy disinfection and reuse, for example, is coupled to the lower cover plate 10, and the first end of the clamp plate 20 is connected to the first arc- The second arc-shaped hole 21 may be provided at a portion corresponding to the hole 11, but the present invention is not limited thereto. Here, the clamp plate 20 may be coupled to the upper cover plate 10 by welding, for example, but is not limited thereto.

The lower cover plate 30 is made of, for example, stainless steel for convenience of disinfection and reuse, is coupled to the lower side of the clamp plate 20, and the first end of the lower cover plate 30 is connected to the second And a third arc-shaped hole 31 at a portion corresponding to the arc-shaped hole 21. The second end of the lower cover plate 30 has a plurality of strips 32, The first arc-shaped hole 11, the second arc-shaped hole 21 and the third arc-shaped hole 31 may be formed with a gap 35, but the present invention is not limited thereto. Here, the lower cover plate 30 may be coupled to the lower portion of the clamp plate 20 by welding, but is not limited thereto. Here, the number of the plurality of strips 32 is, for example, nine but is not limited thereto. Each strip 32 may pass through the gap 54 of the strip tube 50 at the end.

The first end of the upper cover plate 10 and the lower cover plate 30 have the same length and arc shape and the first end of the clamp plate 20 is connected to the upper cover plate 10, The first end of the upper cover plate 10, the clamp plate 20 and the lower cover plate 30 is formed into a first concave groove 36 ). The width of the first concave groove 36 is slightly larger than the width of the tube cover 53 of the strip tube 50 and the force of the force applied to the first concave groove 36 causes the strip tube 50 To the tube cover 53, thereby reducing the downward pressure.

In addition, the second end of the clamp plate 20 of the present invention further includes a plurality of second concave grooves 22 at portions corresponding to the intervals of the plurality of strips 32, 8, but not limited thereto, the second concave groove 22 can receive the tube body 52 of the strip tube 50.

In addition, the second end of the lower cover plate 30 of the present invention has a plurality of circular holes 34 at portions corresponding to the intervals of the plurality of strips 32, the number of which is, for example, 8 The diameter of the circular hole 34 is slightly larger than the diameter of the tube cover 53 and the circular hole 34 is disposed above the tube cover 53 of the strip tube 50 And the tube cover 53 and the tube body 52 can be engaged by applying a force.

3, the strip tube opening / closing apparatus of the present invention is characterized in that when the tube cover 53 of the strip tube 50 is to be opened, the strip tube 50 is placed in the reaction tray 60, The strips 32 of the second end of the lower cover plate 30 each pass through the gap 54 of the strip tube 50 and finally a force upwardly applied to the handle 35 is applied, The tube cover 53 can be stably opened so that the liquid in the tube body 52 protrudes into the other tube body 52 and the tube body 52 can be separated from the tube body 52. [ The liquid is cross-contaminated with the liquid, thereby preventing the accuracy of the analysis from being affected.

4, when the strip tube opening / closing apparatus of the present invention attempts to close the tube cover 53 of the strip tube 50, the strip tube 50 is placed in the reaction tray 60 The tube body 52 is temporarily covered with the tube cover 53 and finally the first concave groove 36 is disposed above the tube cover 53 and the first concave groove 36 is subjected to a force So that the tube cover 53 can be closed. Thereby, the tube cover 53 can be quickly and stably combined with the tube body 52 and the downward pressure can be reduced.

5, when the strip tube opening / closing apparatus of the present invention attempts to close the tube cover 53 of the strip tube 50, the strip tube 50 is placed in the reaction tray 60 The tubular body 52 is temporarily covered with the tube cover 53 and finally the plurality of circular holes 34 are placed on the tube cover 53 and a force is applied to the upper cover plate 10 The tube cover 53 may be pressed. Thereby, the tube cover 53 can be quickly and stably combined with the tube body 52 and the downward pressure can be reduced.

According to an embodiment of the present invention, the lower cover plate has a plurality of strips at one end thereof, each of the strips can pass through the gap of the strip tube, Separating the tube cover of the strip tube and the tube body, reducing vibration to the strip tube; The upper cover plate, the clamp plate and the lower cover plate are made of a stainless steel material for convenience of disinfection and reuse, and the end portion has a first concave groove having a width larger than the width of the strip tube, And the tube cover of the strip tube and the tube body are combined.

It is to be understood that the invention is not limited to the disclosed embodiments and drawings, and that various modifications may be made by those skilled in the art without departing from the scope of the present invention.

10: upper cover plate 11: first arc-shaped hole
20: clamp plate 21: second arc-shaped hole
22: second concave groove 30: lower cover plate
31: Third type hole 32: Strip
33: gap 34: circular hole
35: handle 36: first concave groove
50: strip tube 52: tube body
53: tube cover 54: clearance
60: reaction tray

Claims (7)

An upper cover plate having a first arched hole,
A clamp plate coupled to a lower portion of the upper cover plate and having a first arched portion at a portion corresponding to the first arc-shaped hole,
A plurality of strips which are coupled to the clamp plate and have a first arched portion at a portion corresponding to the arc-shaped hole and a second end that can pass through the gap of the strip tube, The first arc-shaped hole, the second arc-shaped hole and the third arc-shaped hole include a lower cover plate capable of forming a handle;
A strip tube opening / closing device which can separate the tube cover of the strip tube and the tube body by a force applied to the handle, respectively, when the strip tube is disposed in the reaction tray, .
The method according to claim 1,
Wherein the upper cover plate, the clamp plate, and the lower cover plate are made of a stainless steel material for easy disinfection and reuse.
The method according to claim 1,
Wherein the first end of the upper cover plate and the lower cover plate are of the same length and arc shape and the first end of the clamp plate is relatively inwardly tapered relative to the length of the upper cover plate and the lower cover plate, Wherein the first end portions of the upper cover plate, the clamp plate, and the lower cover plate form a first concave groove.
The method of claim 3,
Wherein the width of the first concave groove is slightly larger than the width of the tube cover of the strip tube and the tube cover of the strip tube and the tube body can be engaged by a force applied to the first concave groove. Tube switchgear.
The method according to claim 1,
Wherein the number of the plurality of strips is nine, and a gap is provided between each of the strips.
6. The method of claim 5,
And the second end of the clamp plate further comprises a plurality of second concave grooves having a number of eight that can accommodate the tube body of the strip tube at a portion corresponding to the interval of the plurality of strips. Opening and closing device.
6. The method of claim 5,
Wherein the second end of the lower cover plate further comprises a plurality of circular holes having a number of eight in a portion corresponding to the interval of the plurality of strips, the diameter of the circular hole being slightly larger than the tube cover of the strip tube, Wherein the hole is disposed above the tube cover of the strip tube, and a force is applied so that the tube cover and the tube body can be engaged with each other.
KR1020150060611A 2014-09-15 2015-04-29 Closing and opening device for strip tube KR101880575B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TW103216314U TWM494031U (en) 2014-09-15 2014-09-15 Continuous arranged tube opening and closing device
TW103216314 2014-09-15

Publications (2)

Publication Number Publication Date
KR20160031946A true KR20160031946A (en) 2016-03-23
KR101880575B1 KR101880575B1 (en) 2018-07-20

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KR1020150060611A KR101880575B1 (en) 2014-09-15 2015-04-29 Closing and opening device for strip tube

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TW (1) TWM494031U (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102470163B1 (en) 2020-12-24 2022-11-23 주식회사 바이오티엔에스 Lid heater assembly of pcr apparatus

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683782A (en) * 1986-11-17 1987-08-04 Warburg Richard J Microcentrifuge tube opener
US5253551A (en) * 1990-07-12 1993-10-19 Bio-Pias, Inc. Centrifuge tube and centrifuge tube cap removing and installing tool and method
US5967001A (en) * 1998-01-26 1999-10-19 Qualicon Cap removing tool
US6309603B1 (en) * 1999-02-01 2001-10-30 Drummond Scientific Company Microcentrifuge tube cap opening and closing apparatus and method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683782A (en) * 1986-11-17 1987-08-04 Warburg Richard J Microcentrifuge tube opener
US5253551A (en) * 1990-07-12 1993-10-19 Bio-Pias, Inc. Centrifuge tube and centrifuge tube cap removing and installing tool and method
US5967001A (en) * 1998-01-26 1999-10-19 Qualicon Cap removing tool
US6309603B1 (en) * 1999-02-01 2001-10-30 Drummond Scientific Company Microcentrifuge tube cap opening and closing apparatus and method

Also Published As

Publication number Publication date
TWM494031U (en) 2015-01-21
KR101880575B1 (en) 2018-07-20

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