KR20160012729A - Sap set comprising filter - Google Patents

Sap set comprising filter Download PDF

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Publication number
KR20160012729A
KR20160012729A KR1020140094783A KR20140094783A KR20160012729A KR 20160012729 A KR20160012729 A KR 20160012729A KR 1020140094783 A KR1020140094783 A KR 1020140094783A KR 20140094783 A KR20140094783 A KR 20140094783A KR 20160012729 A KR20160012729 A KR 20160012729A
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KR
South Korea
Prior art keywords
liquid
porous membrane
membrane filter
filter
present
Prior art date
Application number
KR1020140094783A
Other languages
Korean (ko)
Inventor
이낙호
이대희
Original Assignee
성원메디칼 주식회사
이낙호
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 성원메디칼 주식회사, 이낙호 filed Critical 성원메디칼 주식회사
Priority to KR1020140094783A priority Critical patent/KR20160012729A/en
Publication of KR20160012729A publication Critical patent/KR20160012729A/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • A61J1/1456—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using liquid filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

 The liquid set according to the present invention comprises at least one filter and is made of an eco-friendly material which is PVC-Free, so that it is possible to administer the drug (drug or the like) in the body without absorbing the drug in the tube, , PVC-free material, and does not contain any plasticizer components and does not cause hepatotoxicity even during prolonged exposure (administration), and is harmful to di-ethylhexyl phthalate (DEHP) It is possible to safely protect the patient from micro-pathogens that may be present in the hospital because it does not generate a dioxin compound even if it is burned and does not affect the environment, have.

Description

A sap set comprising filter < RTI ID = 0.0 >

The present invention relates to a liquid set including a filter.

In general, liquids such as physiological saline solution, Ringer's solution, glucose solution and fructose solution used in hospitals that treat patients or perform surgery are stored in a liquid container having a certain shape. The liquid container is divided into a liquid bottle and a liquid bag depending on the material of the container.

On the other hand, in order to inject the liquid stored in the liquid container into the patient, a liquid set (disposable sterilized medical instrument) connected to the liquid container must be provided, and the liquid stored in the liquid container is transferred to the blood vessel of the patient through the liquid set.

The fluid set usually consists of a tubing, a regulator flow regulator, a membrane filter, a pointed ball, a 3-way stopcock, a Y-site, a rubber tube, a fixed connector, and a rotatable connector.

Since such a liquid set is generally discarded after a single use, it is necessary to be an environmentally friendly material. In addition, it should be able to prevent air, various bacteria (bacteria, etc.), and foreign substances that may adversely affect the patient from being administered to patients along with sap (medicine) for a long period of time (administration).

Korean Patent Publication No. 2002-0066163 (Aug. 14, 2002)

The present invention relates to a method and apparatus for treating air, various bacteria (bacteria and the like) and foreign matter that can adversely affect a patient during long-term use (administration) without causing environmental problems during disposal including environment- And a filter that can prevent the liquid from being leaked.

In order to achieve the above object, according to an embodiment of the present invention, there is provided a fluid infusion pump comprising: a fluid withdrawing portion for withdrawing fluid from a fluid receptacle; a fluid injecting portion for injecting the fluid; and a fluid receiving portion for transmitting the fluid from the fluid withdrawing portion to the fluid reservoir Wherein the fluid tube provides a set of fluid including one or more filters.

In an exemplary embodiment, the filter may be a porous membrane filter.

In an exemplary embodiment, the porous membrane filter may have a bi-directional or unidirectional filtering structure.

In an exemplary embodiment, the pore diameter in the porous membrane filter may be between 0.2 and 5 mu m.

In one exemplary embodiment, the flow rate per hour of the porous membrane filter may be between 10 and 100 ml / min.

In an exemplary embodiment, at least one selected from the group consisting of the liquid receiving portion, the liquid receiving tube, and the liquid receiving portion may include a Urethane material.

In an exemplary embodiment, the set of liquids includes two porous membrane filters spaced apart from each other on a liquid pipe, the pore diameter of the one porous membrane filter is 0.2 탆, and the porosity of the other porous membrane filter The diameter may be 1.2 탆.

The liquid set including the filter according to the present invention is made of an eco-friendly material such as PVC-Free, which makes it possible to inject drugs (medicines, etc.) into the tubes without absorbing the expensive drugs and without losing the expensive drugs. In addition, since it is a PVC-free material, it does not contain a plasticizer component and does not cause hepatotoxicity even during prolonged exposure (when administered). It is also used as a dihydroxy compound It does not cause harmful substances and does not produce dioxin complex even if it is burned and does not affect the environment.

In addition, the infusion set according to the present invention is equipped with a filter for filtering bacteria and the like in the air, so that the patient can be safely protected from microbacteria that may exist in the hospital.

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 schematically illustrates a set of infusions comprising a filter according to an embodiment of the invention.
2 shows a schematic structure of a filter according to an embodiment of the present invention.
3 shows a schematic structure of a filter according to an embodiment of the present invention.
4 is a photograph of a filter according to an embodiment of the present invention.
5 is a photograph of a filter according to an embodiment of the present invention.
6 is a photograph of a filter according to an embodiment of the present invention.
7 is a photograph of a filter according to an embodiment of the present invention.
FIG. 8 is a graph showing a comparison result of the throughput per hour using the filter according to the embodiment of the present invention and the filter according to the related art, respectively.

In one embodiment for achieving the object of the present invention, a set of liquids including a filter includes a liquid withdrawing portion for withdrawing liquid from the liquid container, a liquid injecting portion for injecting the liquid, and an infusion liquid from the liquid withdrawing portion A set of transfusions comprising a transfusion tube, wherein the transfusion tube may comprise one or more filters.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a fluid set including a filter of the present invention will be described in detail with reference to the accompanying drawings.

FIG. 1 is a schematic view of a set of liquids including a filter according to an embodiment of the present invention. In FIG. 1, the liquid-withdrawing part 100 from which liquid is drawn out from the liquid- And the fluid pipe 200 is connected to a fluid injection unit 300 for injecting fluid into the patient's body. The fluid control part 210 and 220 may be included on the fluid pipe 200. In addition, the filter 400 may be provided on the liquid pipe 200 to remove foreign matter in the liquid. The filter 400 may include one or more filters as needed.

More specifically, the liquid container 50 is a container for storing liquids such as physiological saline solution, Ringer's solution, glucose solution, fructose solution and the like, and can be classified into a liquid bottle or a liquid bag depending on the material of the container.

On the other hand, the liquid withdrawing portion 100 is a portion directly connected to the liquid receiver 50 and the liquid set. The liquid withdrawing part 100 includes an insertion part 110 to be directly inserted into the liquid receiver and a dropping tube 120 to drop the liquid drawn out from the liquid receiver through an insertion part inserted into the liquid receiver 50 Lt; / RTI > Meanwhile, the insertion unit 110 inserted into the receiver may further include additional leakage preventing means for preventing the leakage of the liquid. The leakage preventing means may be, for example, a sealing projection (not shown) .

The size and shape of the liquid withdrawing portion 100 are not particularly limited as long as the liquid receiving portion 100 can easily receive the liquid from the liquid receiving container 50. In one embodiment of the present invention, the liquid withdrawing portion 100 may include an insertion portion 110 and a dropping tube 120.

Meanwhile, the liquid withdrawing portion may include a Urethane material. A conventional liquid set is generally constructed by adding DEHP as a plasticizer to polyvinyl chloride (PVC) resin base to obtain flexibility, which is problematic because it is an endocrine disruptor of the human body. When the human body is exposed to DEHP, metabolic disorders such as birth defects in diabetic mothers, development of diabetes mellitus and metabolic syndrome, and genital disorders may occur. In addition, the PVC material has a problem of environmental pollution due to the characteristics of the liquid set to be discarded after one use, but the urethane material according to the present invention has overcome such a problem.

Meanwhile, the insertion portion 110 is directly inserted into the liquid storage container, thereby receiving the liquid from the liquid storage container and delivering the liquid to the dropping pipe 120. The size and shape of the insertion portion are not particularly limited as long as they can perform the above functions. In an embodiment of the present invention, the insertion portion 110 may have a pipe shape, more specifically, a tube shape having a sharp tip.

Meanwhile, the dropping tube 120 temporarily stores the liquid received from the liquid receiver, and supplies the liquid to the liquid receiver 200 by a predetermined amount. The size or shape of the dropping tube is not particularly limited as long as it can perform the role. In an embodiment of the present invention, the dropping pipe 120 may have a cylindrical shape, and more specifically, may be a cylindrical shape having a width of the upper surface and a width of the lower surface different from each other.

Meanwhile, the insertion portion 110 inserted into the liquid receiver may further include an additional leakage preventing means for preventing leakage of the liquid. The leakage preventing means may be, for example, a sealing projection (not shown) . As the leakage preventing means, the sealing protrusion is a screw-shaped protrusion formed on the outer surface of the insertion portion, and can closely adhere the insertion portion to the liquid receptacle to seal the leakage of the liquid.

Next, the liquid tube 200 receives the liquid from the liquid draw-out unit 100 and transfers the liquid to the liquid injector 300.

The size and shape of the liquid tube 200 are not particularly limited as long as they can transmit the liquid. In one embodiment of the invention, the fluid tube may be in the form of a tube.

Meanwhile, the fluid pipe may include a Urethane material. The conventional liquid set is generally constructed by adding DEHP as a plasticizer to obtain flexibility on a PVC resin base, which is problematic because it is an endocrine disrupting substance in the human body. When the human body is exposed to DEHP, metabolic disorders such as birth defects in diabetic mothers, development of diabetes mellitus and metabolic syndrome, and genital disorders may occur. In addition, the PVC material has a problem of environmental pollution due to the characteristics of the liquid set to be discarded after one use, but the urethane material according to the present invention has overcome such a problem.

Meanwhile, in one embodiment of the present invention, one or more fluid control units 210 and 220 may be included on the fluid pipe 200.

The fluid control unit may be, for example, a simple ON / OFF function (210) for allowing or preventing transmission of the fluid along the fluid tube, and may control the amount of fluid flowing into the fluid reservoir along the fluid pipe (220). ≪ / RTI > The size and shape of the fluid regulating units 210 and 220 are not particularly limited as long as they can appropriately perform the functions, and those commonly used in the related art can be used.

In the liquid set according to the embodiment of the present invention, as shown in FIG. 1, two liquid-liquid adjusting portions may be spaced apart from each other on the liquid-level adjusting portion.

Next, the fluid pipe 200 may include one or more filters 400.

In one embodiment of the present invention, the filter may be a porous membrane filter including a plurality of micro-sized pores.

Meanwhile, in one embodiment of the present invention, the porous membrane filter may be antimicrobially treated to prevent bacterial growth or to block bacteria.

Meanwhile, in one embodiment of the present invention, the porous membrane filter may be composed of a polyethersulfone material. Unlike the conventional filter, the filter does not include a natural rubber latex, a rubber derivative, PVC or hydroxyvinyl chloride, thereby preventing the environmental pollution problem, It is possible to reduce the possibility of giving.

Meanwhile, in an embodiment of the present invention, the diameter of the individual pores formed in the porous membrane filter may be in the range of 0.2 to 17 mu m, and more specifically in the range of 0.2 to 5 mu m. The diameter of the individual pores formed in the membrane used can be selected differently depending on the size of the substance (drug aggregate or precipitate, etc.) to be removed.

Meanwhile, in one embodiment of the present invention, the flow rate of the porous membrane filter per hour may be 10 to 100 ml / min.

Within such a range of individual pore diameters and a flow rate per hour of the porous membrane filter, the porous membrane filter can effectively remove air or contaminated air, as well as provide high filtration, throughput, and flow rate.

In addition, the porous membrane filter can maximize the effect of filtering out various germs (bacteria and the like) and foreign substances within the range of the individual pore diameters and the flow rate per hour of the porous membrane filter.

Meanwhile, the porous membrane filter may have a bidirectional or unidirectional filtering structure (see FIGS. 2 and 3).

2 shows a schematic structure of a porous membrane filter according to an embodiment of the present invention.

Referring to FIG. 2, it can be seen that the porous membrane filter has a bi-directional filtering structure. 2 (a) is a top view of the porous membrane filter, and FIG. 2 (b) is a cross-sectional view of the porous membrane filter. The porous membrane filter according to an embodiment of the present invention has the bi-directional filtering structure as described above, thereby effecting double filtration and treatment of the filtration material.

3 shows a schematic structure of a porous membrane filter according to an embodiment of the present invention.

Referring to FIG. 3, it can be seen that the porous membrane filter has a unidirectional filtering structure. 3 (a) shows a view of the porous membrane filter viewed from above, and FIG. 3 (b) shows a cross section of the porous membrane filter.

Meanwhile, the liquid receiver set including the filter according to the embodiment of the present invention includes a liquid receiver 100 for extracting liquid from the liquid container 50, a liquid injector 300 for injecting the liquid, (400), and the filter may be a plurality of filters, and may have a pore size different from one another, if necessary, A filter having a porosity may be used in combination.

In one embodiment of the present invention, the set of liquids includes two porous membrane filters formed on the liquid pipe spaced apart from each other, the pore diameter of the one porous membrane filter is 0.2 탆, and the other porous membrane filter May have a pore diameter of 1.2 mu m.

More specifically, microbial cells can be effectively blocked if the porous membrane filter comprises individual pores having a size of 0.2 mu m diameter.

On the other hand, when the porous membrane filter includes individual pores having a diameter of 0.8 mu m, the bacteria can not pass through, and the effect is that only the sterilized solution is delivered.

On the other hand, when the porous membrane filter includes individual pores having a size of 1.2 탆 in diameter, it is possible to freely pass the suspended lipid particles while reducing the risk of yeast contamination.

On the other hand, when the porous membrane filter comprises individual pores having a size of 5 탆 diameter, there is an effect suitable for use in total sediment, aggregate and particle reduction.

Therefore, the porous membrane filter used in the liquid set according to the present invention may use a single filter according to the purpose, or a plurality of filters having different sizes of individual pores may be used in combination.

FIG. 4 is a photograph of a liquid set including a porous membrane filter having individual pores having a diameter of 0.2 μm in a liquid pipe according to an embodiment of the present invention. The porous membrane filter including individual pores having a size of 0.2 mu m diameter has an effect of effectively blocking microbial cells having a size similar to or larger than 0.2 mu m. Thus, porous membrane filters with pores of this size are suitable for use in aseptic fluid delivery.

FIG. 5 is a photograph of a liquid set including a porous membrane filter including individual pores having a size of 0.8 mu m in diameter in a liquid-receiving tube according to an embodiment of the present invention. The porous membrane filter including the individual pores having a size of 0.8 mu m in diameter has no effect on the passage of bacteria and is effective in delivering only the sterilized solution.

FIG. 6 is a photograph of a liquid set including a porous membrane filter including individual pores having a diameter of 1.2 탆 in a liquid pipe according to an embodiment of the present invention. The porous membrane filter comprising individual pores with a size of 1.2 탆 diameter can freely pass through the suspended lipid pellets while reducing the risk of yeast contamination. That is, the porous membrane filter having pores of the above-mentioned size is suitable for use in lipid-based liquids.

Meanwhile, FIG. 7 is a photograph of a liquid set including a porous membrane filter including individual pores having a size of 5 탆 diameter in a liquid pipe according to an embodiment of the present invention. The porous membrane filter comprising individual pores of size 5 탆 diameter is suitable for use in total sediment, aggregate and particle reduction.

The liquid injector 300 may include a needle 310 and a lid 320 to inject the liquid sent from the liquid tube 200 into the human body of the patient, particularly, the vein.

The size and shape of the injection needle 310 are not particularly limited as long as they can penetrate the skin of the patient and transmit the fluid to the vein. And prevent a medical accident that may not occur. When the lid part is to be injected into the patient, the lid part is separated from the injection part to expose the injection needle.

As described above, the liquid set including the filter according to the present invention is constituted by an eco-friendly material, which is PVC-free, so that there is no adsorption of sap (medicine etc.) in the tube, I can do it.

In addition, because it is a PVC-free material, it does not contain a plasticizer component and does not cause hepatotoxicity even at prolonged exposure (when administered), and prevents harmful substances such as DEHP, It does not create a dioxin complex and does not affect the environment.

Further, the liquid set according to the present invention is equipped with a filter for filtering bacteria and the like in the air, so that the patient can be safely protected from micro-pathogenic bacteria or air that may be present in the hospital.

Example

Hereinafter, the present invention will be described in more detail with reference to examples of the present invention. However, the scope of the present invention is not limited by the following examples.

Experiment 1

The result of treating the liquid per hour using a porous membrane filter (0.2mic) made of polyethersulfone containing individual pores having a size of 0.2 mu m in diameter according to an embodiment of the present invention, ≪ / RTI >< RTI ID = 0.0 > 2 < / RTI > micron).

The results of the experiment of FIG. 8 are based on the porosity and the pore size of the porous membrane filter. When the porous membrane filter according to the embodiment of the present invention is used, compared to the case of using the conventional porous membrane filter, . ≪ / RTI >

50:
100:
110: insertion portion 120: dropping tube
200: fluid tube
210 and 220:
300:
310: injection needle 320: lid part
400: filter

Claims (7)

A liquid set including a liquid withdrawing portion for withdrawing liquid from a liquid container, a liquid injecting portion for injecting the liquid, and a liquid pipe for delivering the liquid from the liquid withdrawing portion to the liquid reservoir,
Wherein the fluid tube comprises one or more filters. The method according to claim 1,
Wherein the filter is a porous membrane filter. 3. The method of claim 2,
Wherein the porous membrane filter has a bi-directional or unidirectional filtering structure. 3. The method of claim 2,
Wherein the pore diameter in the porous membrane filter is 0.2 to 5 占 퐉. 3. The method of claim 2,
And the flow rate of the porous membrane filter per hour is 10 to 100 ml / min. The method according to claim 1,
Wherein at least one selected from the group consisting of the liquid withdrawing portion, the liquid receiving tube, and the liquid controlling portion comprises a urethane material. 3. The method of claim 2,
The set of the liquids includes two porous membrane filters formed on the liquid pipe and spaced apart from each other,
Wherein the pore diameter of the one porous membrane filter is 0.2 탆 and the pore diameter of the other porous membrane filter is 1.2 탆.
KR1020140094783A 2014-07-25 2014-07-25 Sap set comprising filter KR20160012729A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102233146B1 (en) * 2019-10-22 2021-03-29 대가파우더시스템 주식회사 Infusion filter element for serious patients and infusion set including same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020066163A (en) 2001-02-09 2002-08-14 장양수 A safty injection set

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020066163A (en) 2001-02-09 2002-08-14 장양수 A safty injection set

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102233146B1 (en) * 2019-10-22 2021-03-29 대가파우더시스템 주식회사 Infusion filter element for serious patients and infusion set including same

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