KR20140099854A - Cheonggukjang-pill for improving atopic dermatitis using native grass and manufacturing method therefore - Google Patents

Abstract

Disclosed are a fast-fermented bean paste pill containing native grasses for alleviating atopy and a method for producing the same. The fast-fermented bean paste pill containing native grasses for alleviating atopy and the method for producing the same according to the present invention comprise the steps of (a) preparing water so that soybeans and water which are to be added can have a ratio of 1:1.5 to 1:2 based on volume; (b) adding 15-20 parts by weight of each of plantains and kudzu shoots, 7-10 parts by weight of each of Polygonatum odoratum var. pluriflorum, reeds, and Imperata cylindrica Beauvois var. koenigii Durand et Schinz, and 3-5 parts by weight of each of Staphylea bumalda, bicolor lespedeza, a cherry tree component, sand pear, an elm component, and Philadelphus schrenckii herbs, based on 100 parts by weight of the soybeans prepared after being dipped and washed in the water prepared in step (a) in order to be heated for a particular period of time and then cooled to be steamed so that soft brown boiled beans are produced; (c) fermenting the boiled beans produced in step (b) into fast-fermented bean paste; (d) drying and pulverizing the fermented fast-fermented bean paste which is fermented in step (c); and (e) completing fast-fermented bean paste pills which are molded into pills with a particular diameter. When the fast-fermented bean paste pill according to the present invention is administered to patients who have severe symptoms, especially children or youths who are exposed to several sorts of toxicity in cities and have active fast metabolisms, they can have changed constitutions in which atopy does not occur.

Description

Technical Field [0001] The present invention relates to a cheonggukjang-pill for improving atopic dermatitis,

The present invention relates to atopic improvement, and more particularly, to a method for manufacturing a blue lotion ring for improving atopy containing natural wild fauna.

In recent years, among the skin diseases that indicate abnormalities in all the skin including the hair, nails and claws of mammals including humans, atopic dermatitis is a rapidly growing and difficult-to-treat skin disease that occurs in people with atopic allergies. . The cause of atopic dermatitis has not been clarified yet. However, atopic dermatitis has a history of atopic dermatitis in about 70% of all patients, and it is common in people with allergic disease, especially allergic diseases such as allergic rhinitis and asthma, And is understood as one of immune diseases. The most important characteristic of atopic disease is the initial severe itching, and therefore, patients with atopic dermatitis often become more aggravated by secondary infections due to severe scratching of the skin and by the mental stability and emotional state of the patient. In particular, atopic dermatitis is frequently caused by people with dry skin, weak skin, or persons with insufficient resistance, and may be caused by excessive skin reaction to various pollutants and bacteria such as Staphylococcus aureus. Furthermore, various pollutants, bacteria, and volatile organic compounds in the air, ozone, and the like, which cause skin hypersensitivity reactions, synergize with each other, thereby exacerbating symptoms of atopic dermatitis. Atopic dermatitis affects a considerable number of people, ranging from 0.5% to 1% of the population and 5% to 10% of children.

The age at which atopic skin disease occurs frequently is usually within 2 to 6 months of age, especially in infants under 1 year of age, and 85% is before 5 years of age. Atopic dermatitis is frequently seen in infancy, but in recent years, the number of patients after puberty has increased, and the medical history is also getting longer. In the treatment of atopic dermatitis, medicines such as corticosteroids which can expect a high pharmacological effect are used. However, adverse effects of corticosteroids are becoming a problem, and patients are exposed to a variety of side effects during treatment. Moreover, when corticosteroids are discontinued, a rebound phenomenon frequently occurs, which refers to the worsening of the condition of the affected part after drug withdrawal. As a countermeasure for such side effects, non-steroidal anti-inflammatory drugs or antihistamines which do not contain hormones such as corticosteroids are used, but it is also difficult to cure the disease itself. Therefore, it is urgent to develop a therapeutic agent for relieving or treating atopic dermatitis without side effects.

Korean Patent Laid-open No. 10-2009-0106003, published October 8, 2009, discloses a method for producing a functional composition for alleviating atopic dermatitis originating from natural products. According to the above patent, a method for producing a functional composition for alleviating atopic dermatitis containing anion-generated alkaline ionized water derived from a plant ingredient is provided. The functional composition for atopic dermatitis emollient produced by the above patent does not stimulate skin at all because it contains only ingredients derived from pure natural materials and mitigates atopic dermatitis due to the antioxidative effect of genistein in soybean extract.

In particular, the above-mentioned patent discloses that genistein contained in soybean extract has a strong antioxidative effect by removing superoxidase radical by increasing the production of SOD (superoxidase dismutase) Therefore, it has been pointed out that, when using this antioxidant-active genistein in a composition for relieving atopic dermatitis, it will play a significant role in relieving atopic dermatitis by inhibiting or eliminating harmful oxygen that stimulates atopic skin. Genistein is one of the major isoflavones contained in soybean flour, and is especially contained in fermented soybeans. The efficacy of isoflavones has been largely known in relation to estrogen hormone and is based on the antioxidant effect of genistein, The effect was revealed.

In addition, the patent discloses that soybean curd, chamomile, and licorice contained in the functional composition for alleviating atopic dermatitis exhibit an itching and anti-irritation effect, a sterilizing effect, and an inflammation-inhibiting effect, To remove harmful oxygen that stimulates the atopic skin, and at the same time, it is possible to effectively improve the itching, scarring and inflammation frequently observed in atopic dermatitis.

However, most of the prior arts for alleviating the symptoms of atopic dermatitis, including the above-mentioned conventional arts, take the form of an external application agent applied to the skin. However, when applied at the actual site, the side effects are not so slight, There is a problem that it is not effective and it can not be changed into a constitution which does not cause atopy to people having various constitutions.

On the other hand, studies have been made on the production of atopic dermatological compositions or external dermatological compositions using atorvastatin. Korean Patent Laid-Open No. 10-2007-96163, published on October 2, 2007, discloses a composition for atopic dermatoses. In Korean Patent Laid-Open No. 10-2011-6387 published on January 20, 2011, A composition for preventing and treating irritable skin diseases is disclosed. Korean Patent No. 10-940434, filed on Jan. 27, 2010, discloses a method for manufacturing a health beauty beauty product of the field.

However, the above-described prior art is also made of the external preparation for skin, which is effective for temporary symptom relief by directly reacting with the skin, but it is often difficult to improve the constitution and often recur.

The object of the present invention is to provide a method for preventing or treating atopic dermatitis in a patient who is not a mild symptom when applied in a field, And a method for manufacturing the same.

According to another aspect of the present invention, there is provided a method for manufacturing atopic dermatitis,

(a) preparing water such that the amount of white ground and water to be added is 1: 1.5 to 1: 2 by volume;

(b) 100 to 100 parts by weight of white rice prepared by washing the water prepared in the step (a) after immersion treatment, 15 to 20 parts by weight of plantain, 10 to 10 parts by weight of reeds, reeds and strips, 3 to 5 parts by weight of wood, cherry tree, alder tree, elm and Oishi herb are added for a certain period of time, and then the temperature is lowered to prepare a light brown boiled soybeans by lowering the temperature;

(c) fermenting the boiled soybean produced in the step (b) into chungkukjang;

(d) drying and crushing the fermented Chinese cabbage fermented in the step (c); And

and (e) molding the mixture into a ring having a predetermined diameter to complete a blue-and-white ring.

In accordance with the present invention, the present invention relates to a method for preventing or treating a disease caused by chronic inflammation, which comprises administering to a patient who is not a mild symptom, especially a child or a teenager who lives in an urban area and is exposed to various toxins and metabolism is active, I can improve the symptoms of atopy even by taking my own, can be changed into a constitution that does not cause atopy by improving the constitution.

FIG. 1 is a flow chart showing the main steps of a method for manufacturing a blue-green algae ring for improving atopy containing natural wild fauna according to the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Reference will now be made in detail to the preferred embodiments of the present invention, examples of which are illustrated in the accompanying drawings.

FIG. 1 is a flow chart showing major steps of a method for manufacturing a chrysanthemum ring for improving atopy containing natural wild fauna according to the present invention. Referring to FIG. 1, in a method for producing a chrysanthemum ring for improving atopy containing natural wild fauna according to the present invention, water (a) is added to water to make a mixture of water and white water at a ratio of 1: 1.5 to 1: (Step S100). Next, (b) 100 parts by weight of white rice prepared by washing the water prepared in the step (a) after immersion treatment is treated with 15 to 20 parts by weight of plantain root and 15 to 20 parts by weight, 3 to 5 parts by weight of pepper, cherry, kelp, chestnut, elm and elixir are heated for a certain period of time, and then the temperature is lowered to boil the pale brown beans (Step S102 ). Next, (c) fermenting the boiled soybean produced in step (b) into chungkukjang, and (d) drying and crushing the fermented chinese cabbage fermented in step (c) (step S104). Now, (e) molding is performed with a ring of a constant diameter to complete the sulfur dioxide ring (step S106)

The same weight parts were prepared with respect to those having similar characteristics to those of Japanese horse chestnut, and the experiment was conducted in the following examples and comparative examples. In other words, the same weight was added to each group for plantain and bamboo shoot, roundwood, reed and strip root, red pepper tree, cherry tree, cherry tree, mountain slope tree, elm tree and Oishi herb.

[Example 1]

20 parts by weight of plantain, 10 parts by weight of reeds and reeds, 10 parts by weight of roots and 10 parts by weight of roots, respectively, and 5 parts by weight of cherry trees, cherry trees, mountain climbing trees and elm and Oishi herbs After heating for a certain time, the temperature is lowered to boil the light brown beans to make boiled

[Example 2]

30 parts by weight of plantain and 10 parts by weight of Ryegrass, 15 parts by weight of reeds and reeds and strips of roots, 7 parts by weight of each of red pepper, cherry, cherry, elm and Oishi herbs After heating for a certain time, the temperature is lowered to boil the light brown beans to make boiled

[Example 3]

15 parts by weight of plantain, 10 parts by weight of reeds, 7 parts by weight of reeds and strips, 5 parts by weight of each of red pepper, cedar, cherry, mountain, elm and oats After heating for a certain time, the temperature is lowered to boil the light brown beans to make boiled

[Example 4]

20 parts by weight of plantain, 10 parts by weight of reeds, 7 parts by weight of reeds and reeds, 3 parts by weight of each of red pepper, cedar, cherry, mountain and elm and Oishi herbs After heating for a certain time, the temperature is lowered to boil the light brown beans to make boiled

[Example 5]

15 parts by weight of plantain, 10 parts by weight of reeds and reeds, and 10 parts by weight of roots, respectively, and 3 parts by weight of each of red pepper, cedar, cherry tree, elm and Oishi herbs After heating for a certain time, the temperature is lowered to boil the light brown beans to make boiled

[Comparative Example 1]

10 parts by weight of Ryegrass, reed and strip root were mixed with 100 parts by weight of plantain, and 3 parts by weight of each of red pepper, cherry, cherry, After heating for a few hours, the temperature is lowered to boil the light brown beans.

[Comparative Example 2]

10 parts by weight of plantain and 10 parts by weight of rice gruel were added to 100 parts by weight of white rice paddy, 5 parts by weight of each of red pepper, sorghum, cherry, After heating for a few hours, the temperature is lowered to boil the light brown beans.

[Comparative Example 3]

5 parts by weight of plantain and 10 parts by weight of rootstock, 2 parts by weight of reeds and reeds and strips of roots, 5 parts by weight of each of red pepper, cedar, cherry, mountainous and elm and Oishi herbs After heating for a certain time, the temperature is lowered to boil the light brown beans to make boiled

In order to evaluate the effect of the cheonggukjang ring prepared by the above Examples 1 to 4 and Comparative Examples 1 to 3 on the experimental group having atopic dermatitis symptoms, Symptoms A group of 72 children were randomly assigned to 504 children and adolescents under 15 years of age to make seven groups. The groups were divided into four groups according to the method of Example 1 to Example 4 and Comparative Example 1 to Comparative Example 3, 1 month, 1 hour before lunch, and 1 time before dinner. The degree of symptom relief of atopic dermatitis was evaluated over 3 months, 6 months, 9 months, and 12 months. The evaluation method was evaluated as being alleviated when the symptom was significantly improved as compared with the state of the skin photograph taken before taking by the naked eye, and when the symptom was weakly improved, it was evaluated as being alleviated. ◎: △: Atopic dermatitis symptoms are alleviated significantly in less than 50% to 90% of the whole, △: Atopic dermatitis symptoms are alleviated in less than 50% to 90% of the whole, : Atopic dermatitis was lessened in less than 50% of cases. Table 1 shows the results of the evaluation of the results obtained after the use of the above-described Examples 1 to 4 and Comparative Examples 1 to 3 in an experimental group having symptoms of atopic dermatitis.

division 3 months 6 months 9 months 12 months Example 1 ○ ◎ ◎ ◎ Example 2 △ ○ ○ ◎ Example 3 △ ○ ○ ◎ Example 4 △ △ ○ ○ Comparative Example 1 × × △ △ Comparative Example 2 × × △ △ Comparative Example 3 × △ △ △

[Comparative Evaluation with Examples 1 to 4 and Comparative Examples]

As shown in Table 1, in Examples 1 to 3, the symptoms of atopic dermatitis were remarkably alleviated in more than 90% of the patients when they were continuously taken for 12 months. In Example 4, only 50% to 90% The symptoms of atopic dermatitis were significantly alleviated. However, in Comparative Examples 1 to 3, atopic dermatitis symptoms were alleviated in less than 50% to 90% of the whole, despite a steady salary for 12 months, and less than 50% Atopic dermatitis symptoms have been alleviated.

[Evaluation of Comparative Example 1]

In the case of Example 1, in which 10 parts by weight of oriental, reed and belt roots were added, and 3 parts by weight of red pepper, cedar, cherry, Despite the detoxification effect of wood, cherry tree, mountain tree, elm, and Oryza sativa, the diuretic effect of toxin is insufficient and it is considered that synergistic effect is insufficient.

[Evaluation of Comparative Example 2]

10 parts by weight of plantain and 10 parts by weight of rice paddy were added to 100 parts by weight of white rice paddy, and 5 parts by weight of red pepper, cedar, cherry, mountain, elm and oats In the case of Comparative Example 2, it is considered that the detoxification and diuretic are not properly performed due to insufficient heat to be exerted by the unreinforced reeds and reeds and band roots.

[Evaluation of Comparative Example 3]

5 parts by weight of plantain and 10 parts by weight of rootstock, 2 parts by weight of reeds and reeds and strips of roots, 5 parts by weight of each of red pepper, cedar, cherry, mountain and elm and Oishi herbs In Comparative Example 3, compared with Comparative Examples 1 and 2, although good results were obtained due to the detoxification effect, it was still remarkably effective compared with the present invention due to the lack of diuretic and heat-reducing ingredients Can be confirmed.

As described above, according to the present invention, the present invention provides a compound of the present invention, which is useful for a patient who is not a mild symptom, especially a child or a teenager living in an urban area and exposed to various toxins and active metabolism, In addition, it can improve the symptoms of atopic dermatitis even if it is not applied to the outside of the body, and the symptoms of atopic dermatitis are remarkably improved without application directly to the skin. As a result, atopic dermatitis is not caused by the improvement of the body constitution.

Claims (2)

(a) preparing water such that the white matter to be charged and water are 1: 1.5 to 1: 2 by volume;
(b) 100 to 100 parts by weight of white rice prepared by washing the water prepared in the step (a) after immersion treatment, 15 to 20 parts by weight of plantain, 10 to 10 parts by weight of reeds, reeds and strips, 3 to 5 parts by weight of wood, cherry tree, chestnut tree, elm tree and Oryza sativa are heated for a certain period of time, and then the temperature is lowered to make light brown boiled soybeans.
(c) fermenting the boiled soybeans made in step (b) into chungkukjang;
(d) drying and crushing the fermented Chinese cabbage fermented in the step (c);
and (e) molding the mixture into a ring having a predetermined diameter to complete a chrysanthemum ring. A method for preparing atorvastatin containing natural wild fauna according to claim 1, comprising the steps of:

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