KR20140016783A - Antitumor activity of superior functionality, the salt and its manufacturing method - Google Patents

Abstract

The present invention relates to: functional salt which is obtained by adding new type protein with an excellent anticancer effect to salt, especially bay salt; and a production method thereof. Specifically the present invention relates to: functional salt with an excellent anticancer effect which is obtained by adding 3 wt%, 5 wt%, 10 wt%, 20 wt%, and 30 wt% of new type protein with the excellent anticancer effect based on the amount of salt.

Description

Functional salt with excellent anticancer effect and its manufacturing method {Antitumor Activity of superior functionality, the salt and its manufacturing method}

The present invention relates to a salt and a functional salt prepared by adding a novel protein having excellent anticancer effect to a salt and a patent sun salt in a certain ratio, and a method for producing the same.

Natural salt contains various minerals in addition to sodium chloride, and the ratio is 68 to 69% by weight sodium chloride and 31 to 32% by weight minerals.

However, due to the pollution of seawater due to overuse of chemical fertilizers and environmental pollution of speculative living sewage by part of industrial wastes, we faced the reality that the saltwater of coastal waters could not escape pollution. Or, making a preferred factor for crystal salts, crystal salts and rock salts are made of 99% by weight of sodium chloride, there is a defect that is not good for the human body because there are almost no minerals.

The present invention has been developed to solve the above conventional drawbacks.

The present invention is to provide a functional salt that can contribute to the national health by improving the ingredient ratio of salt and improving the functionality by adding a certain ratio of new protein having excellent anticancer effect to salt, especially sun salt.

The present invention is thus added to the salt, in particular, a new salt protein, excellent anti-cancer effect to the sun salt to increase the pharmacological effect, the new strain protein used in the present invention is mixed with red ginseng powder Bacillus subtilis bacteria involved in the fermentation process of soybean When fermented and grown to form a red ginseng Bacillus subtilis bacteria having a more enhanced function and its anticancer effect has been proved in animal testing, by mixing the substance with the dermis and fermenting once more and heat treatment, Since the new protein is formed during the fermentation stage, a new protein has been proved that is effective in strengthening the anti-cancer effect and immunity. The salt is added to the salt to enhance its functionality, making salt that can help people's health. Good effect that can surpass the seasoning in the market even in the taste preference In which it will be able to gain new functionality salt.

The present invention is characterized in that the composition is added to the salt or sun salt to add a new protein with excellent anticancer effect in the proportion of 3% by weight, 5% by weight, 10% by weight, 20% by weight, 30% by weight relative to the amount of salt.

In addition, the present invention is to put the natural salt in a centrifuge to dehydrate to extract the liver, and to mix the new protein in the range selected from 3% by weight, 5% by weight, 10% by weight, 20% by weight, 30% by weight with respect to the salt amount Next, low temperature drying at 50 to 60 ° C. for 5 to 6 hours in a drier and pulverizing the mass formed in the drying step are carried out to filter the remaining 60 mesh.

The term "nuclear protein" refers to a novel protein obtained by fermenting once more by mixing the dermis with fermented product by mixing soybean and red ginseng and heat treatment.

Boiled soybeans to cool and then put them in a colander so that they overlap each other in a fermentation chamber maintaining a temperature of 42 ~ 45 ℃ fermented for 48 hours to obtain a fermented soybeans;

Extracting the first fermented soybeans from the fermentation chamber, cooled to 10 ° C., and then mixing the red ginseng powder prepared by crushing it into a screw crusher to mix 5-10 wt% of the amount of soybeans;

A second fermentation step of putting the first fermented soybean mixed with red ginseng powder in a colander into a fermentation chamber maintained at 35 to 38 ° C. and fermenting for 25 hours;

Red ginseng was sequentially dried by drying the second fermented fermented product in a drying room at 55-60 ° C. until the water content reaches 13% by weight and pulverizing the dried product with a grinder to form a powder of 120 mesh. Obtained red ginseng and soybean mixed fermentation product containing Bacillus subtilis bacteria, mixed dermis powder with red ginseng and soybean fermented product at 25:75 weight ratio, adjusted to 20 ~ 30% water content, and put into fermentation chamber at 38 ~ 45 ℃. A third fermentation step of fermentation for time;

After the third fermentation and put into a treatment chamber of 68 ~ 72 ℃ heat treatment for 4 hours while shaking to form a new protein;

The new protein is formed by taking out the processed product, milled to 80 mesh and milled the product by heat treatment at 80 ℃ for 6 hours.

In particular, the citrus peel used in the production of new proteins has a high value as a resource because the citrus peel contains a large amount of carotenoids, flavonoids, limonine, limonene, fragrance components, and dietary fiber. In the case of Wenzhou Mandarin, the pigment is caused by carotenoids, such as beta-kryptoxanthin, beta-carotene and zeaxanthin, in particular beta-kryptoxanthin. Beta-kryptoxanthin content in Wenju citrus is 0.78mg / 100g in the flesh, while 5.26mg / 100g in the skin, which is 6.7 times more contained in the skin than the flesh.

To date, studies have shown that ingestion of foods containing carotenoids reduces the incidence of laryngeal cancer, lung cancer, and colorectal cancer, and inhibits the growth of cancer cells and the decay of malignant tumors. In addition, in vitro experiments measuring the effects of carcinogenesis and mouse blood

In the animal experiments to investigate the inhibitory effect on the edema was confirmed that the strong carcinogenic inhibitory activity of beta-kryptoxanthin, the effect was more than five times higher than beta-carotene. Therefore, carotenoids, in particular beta-kryptoxanthin, have strong antioxidant activity and anti-cancer effects, and thus may be essential nutrients to be ingested for human health maintenance and promotion.

In the dermis, in particular, there is a natural substance called Salestrol Q40 that performs antioxidants on the flesh, and human cancer cells contain an enzyme called P450 CYP1B1. Leicester Shcool scientists have discovered that the enzyme is synthesized and destroyed in tangerine peels with Salestrol Q40, and the findings could be a new approach in the treatment of breast, lung, prostate and ovarian cancer.

In addition, the BBC's Internet version of the UK has a study showing that toxins in citrus peels kill cancer cells.

The researchers at the University of Leicester Pharmacy UK found that the substance called 'salvestrol Q40' contained in the citrus peel is transformed into toxic compounds in the cancer cells and destroys the cancer cells, while these substances are concentrated in the peel rather than citrus pulp.

Salvestrol Q40 is a type of phytoalexin, a chemical produced by plants when they fight off external invaders such as insects and fungi.

It has been found to combine with P450 CYP1B1, an enzyme mainly present in cancer cells, to convert it into a toxic substance and to produce cancer cells 20 times more potent than normal cells.

Dr. Hun Tan of the College of Pharmacy, Leicester University, UK, told a BPC study in Manchester that the ingredient Salvestro-Q40 in citrus peels turns into toxins and kills cancer cells when they enter cancer cells. Reported.

Dr Tan finds that the concentration of these components, which are concentrated in the skin rather than the flesh of citrus fruits, encounters a specific enzyme (P450 CYP1B1) that is much more present in cancer cells than normal cells. It is said to be more toxic.

Salvestrol-Q40 is a type of phytoalexin that plants produce to combat external invaders, such as pests and fungi, which is also found in other rapeseed plants and fruits, such as broccoli and bressels sprout. Said.

The substance, however, is made more and more severely, so Tan says the pesticide is used to prevent pests.

Therefore, it is clear that tangerine peel has a therapeutic effect against various tumors, and this fact has already been proved in alumni experiments.

And the Salestrol Q40 in the dermis confirms that there is a characteristic that is more generated when the citrus is mixed and the present invention uses the above principle.

In addition, red ginseng refers to steaming or swelling ginseng or gelatinizing starch of ginseng by other means. Protection, anti-obesity ingredient, anti-aging ingredient, heavy metal detoxification ingredient, stress relief and tonic effect, anemia effect, heart strengthening and blood pressure control, brain function enhancement, immune function enhancement and anti-inflammatory effect, environmental hormone toxicity inhibitory ingredient and germanium content 4149 It is known as (PPM / 100g), yet hematopoietic (造血 作用) to treat anemia and lower blood sugar (,), insulin treatment patients can reduce the dosage, and the adenosine contained in red ginseng When pyroglutamic acid promotes blood circulation in the capillaries to prevent atherosclerosis symptoms and protects the liver, it acts on the endocrine system, leading to sexual behavior and reproductive effects. It is effective indirectly in the family, has anti-inflammatory and anti-tumor effects, and is known to have a protective effect against radiation and softens the skin.

In particular, the most important of the effects of red ginseng is the adaptogen effect has been scientifically proven to have the ability to adapt the body more easily by increasing the defense ability against various harmful action stress from the environment,

Soybeans also contain 41% protein. The amount of protein is the highest among crops, and the composition of amino acids is inferior to meat.

Lysine and tryptophan are essential in the soybeans because they contain a lot of essential nutrition than meat.

Soybeans can be used to prevent or treat arteriosclerosis, myocardial infarction, stroke, and high blood pressure by lowering the amount of cholesterol in the blood. Dietary fiber, polyunsaturated fatty acids (mainly nioleic acid; 51%), saponins, trypsin inhibitors, etc. Is known to be important for lowering cholesterol levels or preventing cancer, and lecithin contained in soybean oil is known to lower cholesterol levels and prevent senile dementia.

Meanwhile, soybean oil contains about 20mg / 100g of vitamin E, which is known to be effective for beauty and anti-aging.

The present invention was able to prepare a salt using the Korean invention patent No. 10-1144471 having a cancer-causing effect using the components contained in red ginseng, soybean, dermis.

Claims (2)

Functional salt with excellent anticancer effect by adding new protein with excellent anticancer effect to salt or sun salt in the proportion of 3% by weight, 5% by weight, 10% by weight, 20% by weight and 30% by weight
A step of preparing the harvested sea salt by putting it in a centrifuge and dehydrating it;
Boil soybeans, cool it, and put it in a colander to overlap each other, put it in a fermentation chamber maintaining a temperature of 42 ~ 45 ℃, ferment for 48 hours,
The fermented soybeans are taken out of the fermentation chamber, cooled to 10 ° C, put into a screw crusher, and the red ginseng powder prepared by mashing is mixed with red ginseng powder so that 5-10% by weight of the amount of soybeans. Put it in fermentation chamber maintaining 35 ~ 38 ℃ and ferment for 25 hours
The fermented product is dried until the moisture content is 13% by weight in a drying room at 55-60 ° C., and then the dried product is powdered to a size of 120 mesh to obtain a fermented product of red ginseng and soybeans containing red ginseng Bacillus subtilis. The dermis powder is mixed with fermented soybean powder at 25:75 weight ratio, adjusted to 20 ~ 30% of water content, and then fermented for 18 hours in a fermentation chamber at 38-45 ° C.
Into the treatment chamber of 68 ~ 72 ℃ heat treatment for 4 hours while shaking to form a new protein,
A new protein production step of extracting the processed product formed with the new protein and milling it into 80 mesh and heat-processing the milled product at 80 ° C. for 6 hours;
New protein mixing step of mixing the new protein in the range selected from 3% by weight, 5% by weight, 10% by weight, 20% by weight, 30% by weight with respect to salt amount,
Putting the mixture into a drier and drying at low temperature at 50 to 60 ° C. for 5 to 6 hours;
Functional salt manufacturing method with excellent anticancer effect prepared by commercializing the dried mixture into 60 mesh size