KR20130141260A - Cardiovascular stent using biodegradable polymer - Google Patents
Cardiovascular stent using biodegradable polymer Download PDFInfo
- Publication number
- KR20130141260A KR20130141260A KR1020120064537A KR20120064537A KR20130141260A KR 20130141260 A KR20130141260 A KR 20130141260A KR 1020120064537 A KR1020120064537 A KR 1020120064537A KR 20120064537 A KR20120064537 A KR 20120064537A KR 20130141260 A KR20130141260 A KR 20130141260A
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- South Korea
- Prior art keywords
- cell
- stent
- column
- cardiovascular
- curve part
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/89—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3882—Hollow organs, e.g. bladder, esophagus, urether, uterus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
- A61F2002/30064—Coating or prosthesis-covering structure made of biodegradable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0057—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof stretchable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
Abstract
Description
The present invention relates to a biodegradable stent for cardiovascular.
A stent is a blood vessel, gastrointestinal tract, or biliary tract, where blood or body fluids cannot flow smoothly due to a malignant or benign disease. Instead of surgery, a stent is inserted into a narrowed or blocked area under X-ray perspective to normalize the flow. Cylindrical medical device used, especially in vascular diseases, the use of the stent is when the arterial diameter is narrowed due to blood clots or lipid deposits in the arteries due to atherosclerosis. The iliac arteries of the pelvis that supply blood flow to the pelvis, the carotid arteries that supply blood flow to the brain, and the renal arteries that supply blood flow to the kidney are used.
Such a stent should be inserted into blood vessels in the body to expand the stenosis intact and maintain a circular hollow shape in the stenosis in order to maintain it. In addition, when the stent is inserted into the serpentine blood vessel, the stent itself should be flexible so as not to damage the vessel wall or the catheter which is the stent insertion device.
At present, efforts have been made to satisfy the above requirements in the case of clinically used stents and developing stents, and Korean Patent Application Publication Nos. 10-2004-0075346, US Pat. In heading 74.203, a description has been given of a stent having a structure in which the shape of the same cell is regularly repeated.
However, in addition to the above-described prior art, the development of a stent structure for improving the expansion force and flexibility of the stent itself is constantly required.
SUMMARY OF THE INVENTION The present invention has been made to solve the above problems, and an object thereof is to provide a technique related to a stent structure having excellent expansion force and flexibility.
In one aspect of the present invention, a cardiovascular biodegradable stent includes: a first bent portion formed with at least four bends in order to achieve this object; And a second bent part connected to one side of the first bent part and having a shape left and right symmetrical with the first bent part; The first curved portion and the second curved portion are connected to each other to form a cell, the cell is connected to another cell adjacent to the cell in the horizontal direction, the plurality of cells connected in the horizontal direction The column may be wound to form a cylindrical body.
Here, a column may be connected to another column adjacent in the longitudinal direction to form a plurality of rows.
In addition, the cardiovascular biodegradable stent includes a first row of the plurality of cells are connected; A second column formed by connecting the plurality of cells and adjacent to the first column; A third column formed by connecting the plurality of cells and adjacent to the second column; A first connector connecting at least one cell constituting the first column and any one cell constituting the second column; And a second connector connecting at least one cell constituting the second column and any one cell constituting the third column. The first connector and the second connector may be formed to be inclined in a symmetrical direction with respect to the second column.
In addition, a circular ring may be formed to extend in at least one of the cells constituting one end of the body.
In addition, a radiopaque marker may be coated on the inner circumferential surface of the circular ring.
As described above, the present invention has the following effects.
First, in the present invention, as a plurality of bends are formed in the first and second bends constituting each cell, the material density of the stent is increased. As the material density of the stent increases, the stent inserted into the stenosis has a good degree of expansion in the hollow radius direction.
Second, the cells constituting each column and the cells are connected by the inclined connection portion, which increases the flexibility of the stent. Thus, even if the stent is inserted into the severely curved stenosis, the flexibility of the stent minimizes damage to the inner wall of the stenosis.
Therefore, the stent according to the present invention has an effect of expanding the diameter of the constriction site and stably maintaining the expanded diameter.
1 is a side view showing a stent according to the present invention.
Fig. 2 is a developed view of the stent of Fig. 1 on a plane.
3 illustrates a cell shape of one of a plurality of cells constituting the stent of the present invention.
Figure 4 is a planar development of the stent according to the present invention, showing a portion of Figure 2.
The preferred embodiments of the present invention will be described in more detail with reference to the accompanying drawings, in which the technical parts already known will be omitted or compressed for simplicity of explanation.
Cardiovascular
The cardiovascular
Here, the polymer containing a phosphorylcholine group includes poly (2-methacryloylethylethyl phosphorylcholine-co-n-butyl methacrylate (PMB), poly (MPC-co-BMA-co-methacrylic acid (MA (PMBAc), poly (MPC-co-BMA), poly (MPC-co-BMA-co-p-nitrophenyoxycarbonyl (polyoxyethylene) methacrylate (MEONP)) (PMBN), poly (MPC-co-n-octylacrylamide-co-NIPAM) (PMON) and copolymers thereof.
The cardiovascular
In one embodiment of the present invention, the
The
The
Cells constituting the cardiovascular
Since each cell constituting the cardiovascular
As a plurality of bends are formed in the
As shown in Figure 4, the hollow cylindrical body constituting the
In one embodiment of the present invention, each cell is connected to each other by the
Here, the
Even if the cardiovascular
Meanwhile, a
For example, as shown in Figure 4, any one cell of the first row (Ι) located at one end of the body of the row constituting the cylindrical body of the stent is formed with a
While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. And the scope of the present invention should be understood as the following claims and their equivalents.
100 biodegradable stent for cardiovascular
110: first cell
111: first bend
112: second bend
120: second cell
121: first bent portion
130: third cell
132: second bend
140: fourth cell
142: second bend
150: first connection
160: second connection portion
170: circular ring
Ι: first row
Ⅱ: second row
Ⅲ: third column
Claims (5)
A second bent part connected to one side of the first bent part and having a shape left and right symmetrical with the first bent part; Lt; / RTI >
The first bend and the second bend are connected to each other to form a cell, the cell is connected to another cell adjacent to the cell in a transverse direction, and the plurality of cells connected in the transverse direction form a column, Is wound and formed to form a cylindrical body
Biodegradable Stents for Cardiovascular.
The rows are connected to another row adjacent in the longitudinal direction to form a plurality of rows
Biodegradable Stents for Cardiovascular.
The cardiovascular biodegradable stent
A first column in which the plurality of cells are connected;
A second column formed by connecting the plurality of cells and adjacent to the first column;
A third column formed by connecting the plurality of cells and adjacent to the second column;
A first connector connecting at least one cell constituting the first column and any one cell constituting the second column; And
A second connector connecting at least one cell constituting the second column and any one cell constituting the third column; Lt; / RTI >
The first connector and the second connector is characterized in that the inclined in a direction symmetrical with respect to the second row, characterized in that
Biodegradable Stents for Cardiovascular.
At least one of the cells constituting one end of the body is characterized in that the circular ring is formed extending
Biodegradable Stents for Cardiovascular.
The inner circumferential surface of the circular ring is characterized in that the radiopaque marker is coated
Biodegradable Stents for Cardiovascular.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020120064537A KR20130141260A (en) | 2012-06-15 | 2012-06-15 | Cardiovascular stent using biodegradable polymer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020120064537A KR20130141260A (en) | 2012-06-15 | 2012-06-15 | Cardiovascular stent using biodegradable polymer |
Publications (1)
Publication Number | Publication Date |
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KR20130141260A true KR20130141260A (en) | 2013-12-26 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020120064537A KR20130141260A (en) | 2012-06-15 | 2012-06-15 | Cardiovascular stent using biodegradable polymer |
Country Status (1)
Country | Link |
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KR (1) | KR20130141260A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019093710A1 (en) * | 2017-11-09 | 2019-05-16 | ㈜시지바이오 | Stent and manufacturing method therefor |
WO2022240255A1 (en) * | 2021-05-13 | 2022-11-17 | 전남대학교산학협력단 | Biodegradable stent and manufacturing method therefor |
-
2012
- 2012-06-15 KR KR1020120064537A patent/KR20130141260A/en not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019093710A1 (en) * | 2017-11-09 | 2019-05-16 | ㈜시지바이오 | Stent and manufacturing method therefor |
WO2022240255A1 (en) * | 2021-05-13 | 2022-11-17 | 전남대학교산학협력단 | Biodegradable stent and manufacturing method therefor |
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