KR20130134866A - Glucose measuring device of an unification module structure - Google Patents

Glucose measuring device of an unification module structure Download PDF

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KR20130134866A
KR20130134866A KR1020120058726A KR20120058726A KR20130134866A KR 20130134866 A KR20130134866 A KR 20130134866A KR 1020120058726 A KR1020120058726 A KR 1020120058726A KR 20120058726 A KR20120058726 A KR 20120058726A KR 20130134866 A KR20130134866 A KR 20130134866A
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blood glucose
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안인영
김용범
정하용
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(주)씨큐엠에스
안인영
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    • A—HUMAN NECESSITIES
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    • A61B5/150007—Details
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
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Abstract

The present invention provides a blood sugar measuring device of an unification module structure, characterized by comprising a strip connector which is installed in an external body thereof and has a sensor strip fixated by being inserted thereto; an unification module chip part which supplies a measuring voltage set by the sensor strip, amplifies a blood sugar measuring current detected by the sensor strip, analyzing the blood sugar measuring current and then outputs the current blood sugar measuring values; and a display which displays the blood sugar measuring values outputted by the unification module chip part to the outside. The present invention corrects a measurement error of voltage to blood sugar detecting value in the different biosensors of the different manufacturing companies by realizing in the unification module the main components including a micom of the blood sugar measuring device to which the biosensor for measuring the blood sugar is inserted and equipping the error correction procedure of the multi equation type in the unification module. Also, since the components including the multiple micoms separately arranged in the internal substrate of the blood sugar measuring device are integrated and realized in the single unification module, it is not necessary to separately adopt the main components including the high-priced micom of the blood sugar measuring device, thereby manufacturing the blood sugar measuring device having the simple structure. [Reference numerals] (AA) Measuring value;(BB) Blood sugar variation curve according to an actual measuring value;(CC) Blood sugar variation curve according to the existing linear equation;(DD) Blood sugar value;(EE) There are unmatched sections in view of the entire section by the blood sugar calculation equation according to the existing linear equation

Description

단일화모듈구성의 혈당측정장치{glucose measuring device of an unification module structure}Glucose measuring device of an unification module structure

본 발명은 단일화모듈구성의 혈당측정장치에 관한 것으로, 특히 혈당측정장치의 내부기판에 별도로 다수개 배치되어 있는 마이컴을 비롯한 구성부품들을 하나의 단일화모듈내로 집적시켜 구현하기 때문에 별도로 고가의 마이컴을 비롯한 혈당측정장치의 주요구성부품들을 채용할 필요가 없으므로 그에 따라 혈당측정장치의 구조를 매우 간편하게 제조할 수 있는 단일화모듈구성의 혈당측정장치에 관한것이다. The present invention relates to a blood glucose measurement apparatus having a single module configuration, and in particular, since it implements by integrating components including a microcomputer, which are separately arranged on the internal substrate of the blood glucose measurement apparatus, into a single single module, including an expensive microcomputer separately. Since the main components of the blood glucose measurement apparatus do not need to be employed, the present invention relates to a blood glucose measurement apparatus having a single module configuration that can manufacture the structure of the blood glucose measurement apparatus very easily.

일반적으로 당뇨는 신체의 췌장에서 분비되는 인슐린이 부족하거나, 또는 분비되는 인슐린이 비정상적으로 기능함에 의해 체내에서 당분 흡수가 이루어지지 않는 만성적 질환을 의미하는 것으로, 당뇨 환자의 경우에는 혈액내의 혈당수치(혈당)가 매우 중요하다. 즉, 혈액 속의 혈당이 일정수치의 상한 값 보다 높거나 하한 값보다 낮아지게 되면 환자가 쇼크를 일으키게 되므로, 당뇨 환자의 혈당을 안정범위 내에서 유지시키는 것이 매우 중요하다. 따라서 상기와 같은 당뇨 환자는 체계적이면서 주기적으로 혈당측정장치를 통해 혈당측정으로 정상적인 혈당치(글루코스 농도 약 100mg/dl)를 유지해야 한다. 여기서, 상기와 같은 혈당측정장치는 혈당측정용 바이오센서를 구비하여 바이오센서의 측정부에 채혈한 혈액을 넣어 혈당을 측정하는 하게된다.
In general, diabetes refers to a chronic disease in which the body does not absorb sugar due to lack of insulin secreted from the pancreas of the body or abnormal function of insulin secreted. In the case of diabetics, blood glucose levels in blood ( Blood sugar) is very important. In other words, if the blood glucose in the blood is higher than the upper limit or lower than a certain value, the patient will be shocked, it is very important to maintain the blood sugar within the stable range of diabetes patients. Therefore, such a diabetic patient has to maintain a normal blood sugar level (glucose concentration of about 100mg / dl) by measuring blood glucose systematically and periodically through a blood glucose measurement device. Here, the blood glucose measurement apparatus as described above is provided with a blood glucose measurement biosensor to measure the blood sugar by putting the blood collected in the measurement unit of the biosensor.

여기서 상기와 같은 혈당측정장치와 관련된 선행기술로는 주식회사 아이센스에 의해 출원공개된 한국공개특허공보 제2010-0135545호(발명의 명칭: 혈당측정장치 및 방법; 공개일자: 2010년12월27일)가 공지되어 있다.Here, the prior art related to such a blood glucose measurement apparatus is disclosed in Korean Patent Application Publication No. 2010-0135545 filed by I-Sense Co., Ltd. (Invention: Blood glucose measurement apparatus and method; Publication date: December 27, 2010 Is known.

그러면, 상기와 같은 종래 혈당측정장치는 도 1에 도시된 바와같이 혈당측정용 바이오센서(70;이하 센서스트립)가 삽입고정되는 스트립커넥터(71)와;     Then, the conventional blood glucose measurement apparatus as shown in Figure 1, the blood glucose measurement biosensor 70 (hereinafter the sensor strip) is inserted into the strip connector 71 and fixed;

상기 스트립커넥터(71)에 삽입된 센서스트립(70)으로 전압소스부(72)에 의해 설정된 전압신호를 공급시키는 아날로그스위치(73)와;       An analog switch (73) for supplying a voltage signal set by the voltage source unit (72) to the sensor strip (70) inserted into the strip connector (71);

상기 센서스트립(70)에 의해 측정된 아날로그의 혈당 측정전류를 일정레벨로 증폭하여 출력시키는 OP 앰프부(74)와;      An OP amplifier unit 74 for amplifying and outputting an analog blood glucose measurement current measured by the sensor strip 70 to a predetermined level;

상기 OP 앰프부(74)로부터 출력된 혈당 측정전류를 분석처리한 후 현재의 혈당측정치를 산출하여 디스플레이(75)를 통해 표시시키고 키입력부(76)를 통해 입력된 센서스트립(70)의 코드신호를 파악한 다음 해당 센서스트립(70)의 동작전압을 전압소스부(72)를 통해 공급시키는 MCU(76)를 포함한다.      After analyzing the blood sugar measurement current output from the OP amplifier unit 74, the current blood sugar measurement value is calculated and displayed on the display 75, and the code signal of the sensor strip 70 input through the key input unit 76. After identifying the and includes the MCU 76 for supplying the operating voltage of the sensor strip 70 through the voltage source unit 72.

그리고 상기 MCU(76)는 혈당측정장치(77)에서 조작되는 정보를 저장하는 메모리부(78)가 연결된다.      In addition, the MCU 76 is connected to a memory unit 78 for storing information to be operated in the blood glucose measurement device 77.

한편 상기와 같은 종래 혈당측정장치의 동작은 먼저, 측정자가 측정을 위해 센서스트립(70)를 스트립커넥터(71)에 삽입고정시킨다. 그리고 상기 혈당측정장치(77)의 키입력부(76)를 통해 상기 센서스트립(70)의 코드신호를 입력시켜주면 상기 혈당측정장치(77)의 MCU(76)는 상기 센서스트립(70)의 코드신호를 인식하여 메모리부(78)에 저장된 해당 센서스트립(70)의 동작전압을 파악하고 전압소스부(72)를 통해 해당 센서스트립(70)의 동작전압을 생성하여 아날로그스위치(73)로 출력시킨다. 그러면, 상기 아날로그스위치(73)는 상기 스트립커넥터(71)에 삽입된 해당 센서스트립(70)으로 설정된 전압신호를 공급시키므로 통상의 측정이 실행된다.     On the other hand, the operation of the conventional blood glucose measurement apparatus as described above, the measurer first inserts the sensor strip 70 into the strip connector 71 for measurement. When the code signal of the sensor strip 70 is inputted through the key input unit 76 of the blood sugar measuring device 77, the MCU 76 of the blood sugar measuring device 77 codes the code of the sensor strip 70. Recognizes the signal to determine the operating voltage of the corresponding sensor strip 70 stored in the memory unit 78, generates the operating voltage of the corresponding sensor strip 70 through the voltage source unit 72 and outputs to the analog switch 73 Let's do it. Then, the analog switch 73 supplies the voltage signal set to the corresponding sensor strip 70 inserted into the strip connector 71, so that ordinary measurement is performed.

이 과정에서 상기 센서스트립(70)이 측정자의 채혈을 통해 혈당을 측정한 후 측정된 아날로그의 혈당 측정전류를 OP 앰프부(74)를 통해 일정레벨로 증폭하여 MCU(76)로 입력시킨다. 그러면 상기 MCU(76)는 상기 OP 앰프부(74)로부터 출력된 혈당 측정전류를 분석처리한 후 현재의 혈당측정치를 산출하여 디스플레이(75)상에 표시시키므로 측정자가 자신의 현재 혈당치를 확인하게된다.       In this process, the sensor strip 70 measures blood glucose through a blood collection of a measurer, and then amplifies the measured blood glucose measurement current to a predetermined level through the OP amplifier unit 74 and inputs it to the MCU 76. Then, the MCU 76 analyzes the blood glucose measurement current output from the OP amplifier unit 74 and calculates and displays the current blood glucose measurement value on the display 75 so that the measurer can check his / her current blood sugar level. .

그러나, 상기와 같은 종래 혈당측정장치는 혈당측정장치의 내부기판에 별도로 고가의 MCU와 다수개의 구성부품들을 배치하여 제조하였기 때문에 혈당측정장치의 제조비용을 상당히 증가시켰으며, 또한 혈당측정시에도 센서스트립의 동작전압이 제조사마다 각기 달라 도 2에 도시된 바와같이 혈당측정장치가 전압대 혈당검출값의 측정을 정밀하게 조절해주지 못해 혈당측정값을 일차방정식의 그래프형태로 처리하여 혈당측정치를 산출하므로 그에 따라 혈당측정의 정밀성을 확보하기가 매우 어렵다는 문제점이 있었다.       However, since the conventional blood glucose measurement apparatus is manufactured by arranging an expensive MCU and a plurality of components separately on the internal substrate of the blood glucose measurement apparatus, the manufacturing cost of the blood glucose measurement apparatus is significantly increased, and also a sensor for blood glucose measurement is used. As the operating voltage of the strip varies from manufacturer to manufacturer, as shown in FIG. 2, the blood glucose measurement apparatus cannot precisely control the measurement of the voltage vs. the blood glucose detection value. Thus, the blood glucose measurement value is processed as a graph of the first equation to calculate the blood glucose measurement value. Accordingly, there was a problem that it is very difficult to secure the precision of blood glucose measurement.

이에 본 발명은 상기와 같은 종래 기술의 제반 문제점을 해결하기위해 발명된 것으로, 혈당측정용 바이오센서가 삽입되는 혈당측정장치의 마이컴을 포함한 주요 구성부품들을 단일화모듈내에 구현한 후 상기 단일화모듈내에 다차방정식형태의 오차보정절차를 탑재하여 제조사마다 각기 다른 상기 바이오센서의 전압대 혈당검출값에 따른 측정오차를 보정해주므로써, 혈당측정장치의 혈당측정품질을 상당히 향상시키는 단일화모듈구성의 혈당측정장치를 제공함에 그 목적이 있다.Accordingly, the present invention has been invented to solve the above-mentioned problems of the prior art, and after implementing the main components including the microcomputer of the blood glucose measurement apparatus into which the blood glucose measurement biosensor is inserted into the unification module, Equation type error correction procedure to correct the measurement error according to the blood glucose detection value of the biosensor, which is different for each manufacturer, to improve the blood glucose measurement quality of the blood glucose measurement device of a single module configuration blood glucose measurement device The purpose is to provide.

본 발명의 또 다른 목적은 혈당측정장치의 단일화모듈에 제조사가 각기 다른 혈당측정용 바이오센서를 삽입하더라도 단일화모듈이 다차방정식형태의 오차보정절차를 통해 바이오센서의 전압대 혈당검출값에 따른 측정오차를 보정해주므로 그에 따라 혈당측정장치의 측정정밀성을 향상시키는 단일화모듈구성의 혈당측정장치를 제공하는데 있다.
Another object of the present invention is that even if a manufacturer inserts different biosensors for blood glucose measurement into a single module of the blood glucose measurement apparatus, the measurement module according to the voltage vs. blood glucose detection value of the biosensor through the error correction procedure of the multiple equation type. The present invention provides a blood glucose measurement apparatus having a unitary module configuration that improves the measurement accuracy of the blood glucose measurement apparatus.

상기와 같은 목적을 달성하기 위한 본 발명은 혈당측정장치의 외부몸체에 설치되고 센서스트립이 삽입고정되는 스트립커넥터와;The present invention for achieving the above object and a strip connector is installed on the outer body of the blood glucose measurement apparatus and the sensor strip is fixed;

상기 센서스트립으로 설정된 측정전압을 공급하고 상기 센서스트립에 의해 검출된 혈당 측정전류를 증폭하고 상기 혈당 측정전류를 분석처리한 후 현재의 혈당측정치를 산출하는 단일화 모듈칩부와;A unified module chip unit for supplying the measurement voltage set to the sensor strip, amplifying the blood glucose measurement current detected by the sensor strip, analyzing the blood sugar measurement current, and calculating a current blood glucose measurement value;

상기 단일화 모듈칩부에 의해 산출된 혈당측정치를 외부로 표시하는 디스플레이를 포함하는 것을 특징으로 하는 단일화모듈구성의 혈당측정장치를 제공한다.It provides a blood glucose measurement apparatus of the unitary module configuration comprising a display for displaying the blood sugar measurement value calculated by the unit module module to the outside.

상기와 같은 본 발명에 의하면, 혈당측정용 바이오센서가 삽입되는 혈당측정장치의 마이컴을 포함한 주요 구성부품들을 단일화모듈내에 구현한 후 상기 단일화모듈내에 다차방정식형태의 오차보정절차를 탑재하여 제조사마다 각기 다른 상기 바이오센서의 전압대 혈당검출값에 따른 측정오차를 보정해주므로 그에따라 혈당측정장치의 혈당측정품질을 상당히 향상시키는 효과가 있다.According to the present invention as described above, after implementing the main components, including the microcomputer of the blood glucose measurement device into which the blood glucose measurement biosensor is inserted into the unified module, the error correction procedure of a multi-order equation form in the unified module, each manufacturer Since the measurement error according to the voltage-to-blood glucose detection value of the other biosensor is corrected, there is an effect of significantly improving the blood glucose measurement quality of the blood glucose measurement apparatus.

또한 상기와 같은 본 발명은 혈당측정장치의 내부기판에 별도로 다수개 배치되어 있는 마이컴을 비롯한 구성부품들을 하나의 단일화모듈내로 집적시켜 구현하기 때문에 별도로 고가의 마이컴을 비롯한 혈당측정장치의 주요구성부품들을 채용할 필요가 없으므로 그에 따라 혈당측정장치의 구조를 매우 간편하게 제조할 수 있는 효과도 있다.In addition, the present invention as described above is implemented by integrating the components including the microcomputer separately disposed on the internal substrate of the blood glucose measurement device into a single module, so that the main components of the blood glucose measurement device including the expensive microcomputer separately Since there is no need to employ, there is also an effect that can be manufactured very simply the structure of the blood glucose measurement device.

더 나아가, 상기와 같은 본 발명은 혈당측정장치의 단일화모듈에 제조사가 각기 다른 혈당측정용 바이오센서를 삽입하더라도 단일화모듈이 다차방정식형태의 오차보정절차를 통해 바이오센서의 전압대 혈당검출값에 따른 측정오차를 보정해주므로 그에 따라 혈당측정장치의 측정정밀성을 향상시키는 효과도 있다.
Furthermore, according to the present invention as described above, even if the manufacturer inserts different blood glucose measurement biosensors into the unification module of the blood glucose measurement apparatus, the unification module according to the voltage vs. blood glucose detection value of the biosensor through the error correction procedure of the multi-order equation type. Since the measurement error is corrected, there is also an effect of improving the measurement accuracy of the blood glucose measurement device.

도 1은 종래 혈당측정장치를 설명하는 설명도.
도 2는 종래 혈당측정장치에 의해 구현되는 전압 대 혈당검출값에 대한 그래프.
도 3은 본 발명의 혈당측정장치를 설명하는 설명도.
도 4는 본 발명의 혈당측정장치의 다차방정식방식에 의해 구현되는 전압 대 혈당검출값에 대한 그래프.
도 5의 (a-c)는 본 발명의 혈당측정장치에 의해 구현되는 다중전압의 일례를 설명하는 파형도.1 is an explanatory diagram illustrating a conventional blood glucose measurement apparatus.
Figure 2 is a graph of the blood glucose detection value versus voltage implemented by the conventional blood glucose measurement apparatus.
3 is an explanatory diagram illustrating a blood glucose measurement apparatus of the present invention.
Figure 4 is a graph of the voltage versus blood glucose detection value implemented by the multi-order equation of the blood glucose measurement apparatus of the present invention.
5A is a waveform diagram illustrating an example of multiple voltages implemented by the blood glucose measurement apparatus of the present invention.

이하, 본 발명을 첨부된 예시도면에 의거 상세히 설명한다.Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.

본 발명은 도 3에 도시된 바와 같이 혈당측정장치(5)의 외부몸체에 설치되고 센서스트립(1)이 삽입고정되는 스트립커넥터(2)와;The present invention is a strip connector (2) is installed on the outer body of the blood glucose measurement apparatus (5) and the sensor strip (1) is inserted and fixed as shown in FIG.

상기 센서스트립(1)으로 설정된 측정전압을 공급하고 상기 센서스트립(1)에 의해 검출된 혈당 측정전류를 증폭하고 상기 혈당 측정전류를 분석처리한 후 현재의 혈당측정치를 산출하는 단일화 모듈칩부(3)와;The unified module chip unit 3 which supplies the measurement voltage set to the sensor strip 1, amplifies the blood glucose measurement current detected by the sensor strip 1, analyzes the blood glucose measurement current, and calculates a current blood glucose measurement value. )Wow;

상기 단일화 모듈칩부(3)에 의해 산출된 혈당측정치를 외부로 표시하는 디스플레이(4)를 포함한다.And a display 4 for displaying the blood glucose measurement value calculated by the unified module chip unit 3 to the outside.

여기서, 상기 단일화 모듈칩부(3)는 마이컴, A/D 컨버터, LCD 드라이버, 아날로그 스위치, OP 앰프, 메모리부, 써미스터 등을 하나의 반도체칩에 집적화하여 구성한 것이다. Here, the unified module chip unit 3 is configured by integrating a microcomputer, an A / D converter, an LCD driver, an analog switch, an OP amplifier, a memory unit, a thermistor, and the like into one semiconductor chip.

그리고 상기 단일화 모듈칩부(3)는 (수학식 1)의 다차방정식형태의 오차보정절차를 구비하여 제조사마다 각기 다른 상기 센서스트립(1)의 전압대 혈당검출값에 따른 측정오차를 도 4에 도시된 바와같이 보정해주는 기능을 수행한다.In addition, the unified module chip unit 3 has an error correction procedure in the form of a multi-order equation of Equation (1), and shows measurement errors according to voltage vs. blood glucose detection values of the sensor strip 1 that are different for each manufacturer. Perform the calibration function as shown.

[수학식 1][Equation 1]

혈당값 = Blood sugar level =

Figure pat00001
Figure pat00001

여기서, X: 바이오센서에서 측정한 uA 단위의 전류 측정값( 혈당 농도에 따라 반응 전류 값이 변함 ),              X is the current measurement value in uA measured by the biosensor (reaction current value changes according to blood glucose concentration),

a, b, c, d, e, f : 전류값 변화를 혈당값 변화로 만든 수식 계산용 상수 값            a, b, c, d, e, f: constant value for calculating the formula that changes the current value into the blood sugar value

또한, 상기 단일화 모듈칩부(3)는 센서스트립(1)의 코드값을 입력시켜 줄 경우 해당 코드값에 따른 최적의 동작전압을 저장된 정보내에서 검색하고 그 검색된 해당 센서스트립(1)의 동작전압을 생성하여 해당 센서스트립(1)으로 출력시키므로 센서스트립(1)이 최적의 엔자임반응을 가지고 혈당측정을 실행할 수 있게한다.In addition, when the unified module chip unit 3 inputs the code value of the sensor strip 1, the optimal operating voltage according to the code value is searched in the stored information, and the detected operating voltage of the corresponding sensor strip 1 is detected. It generates and outputs to the sensor strip (1), so that the sensor strip (1) can perform the blood glucose measurement with the optimal enzyme response.

상기와 같은 엔자임반응은 전압에 따라 그 반응을 달리할 수 있으며, 통상 해당 센서스트립(1)에 지정된 동작전압을 인가받을 때 고 엔자임반응을 보인다.The enzyme reaction as described above may vary in response to the voltage, and usually exhibits a high enzyme reaction when the operating voltage specified in the corresponding sensor strip 1 is applied.

따라서, 상기 단일화 모듈칩부(3)는 제조사가 각기 다른 센서스트립(1)의 코드신호를 인식한후 해당 센서스트립(1)에 맞는 다중동작전압을 예컨대, 도 5의 (a-c)에 도시된 바와같이 생성하여 해당 센서스트립(1)에 공급시키는 기능을 수행하게된다.
Therefore, the unified module chip unit 3 recognizes the code signals of the different sensor strips 1 by the manufacturer, and then displays the multi-operation voltages corresponding to the corresponding sensor strips 1, for example, as shown in FIG. It generates together and supplies to the sensor strip (1).

그리고 상기 A/D 컨버터는 14bit 내지 24bit를 사용하는데, 특히 18 bit를 사용하는 것이 바람직하다.The A / D converter uses 14 bits to 24 bits, particularly 18 bits.

또한, 상기 단일화 모듈칩부(3)는 센서스트립(1)에 구비된 측정부()의 온도를 측정하여 단일화 모듈칩부(3)로 입력시키는 적외선검출센서(6) 혹은 IR센서가 연결된다.      In addition, the unitary module chip unit 3 is connected to an infrared detection sensor 6 or an IR sensor that measures the temperature of the measuring unit (1) provided in the sensor strip 1 and inputs it to the unitary module chip unit 3.

상기 단일화 모듈칩부(3)는 적외선검출센서(6) 혹은 IR센서에 의해 검출된 센서스트립(1)의 측정부(7)의 온도를 이용하여 현재 측정된 혈당측정치의 온도오차를 보정해준다. 통상 측정부의 물질은 상온에서 늦게 반응하는데 비해 혈액은 즉시 반응하여 오차가 발생한다.
The unified module chip unit 3 corrects the temperature error of the currently measured blood glucose measurement by using the temperature of the measuring unit 7 of the sensor strip 1 detected by the infrared detection sensor 6 or the IR sensor. In general, the measurement unit reacts late at room temperature, whereas the blood reacts immediately and an error occurs.

그리고 상기 혈당측정장치(5)에는 기능제어신호를 입력시켜주는 키입력부(8)와, 혈당측정장치(5)에 동작전원을 공급시키는 전원공급부(9)가 구비된다.
The blood glucose measurement apparatus 5 includes a key input unit 8 for inputting a function control signal, and a power supply unit 9 for supplying operation power to the blood glucose measurement apparatus 5.

다음에는 상기와 같은 구성으로 된 본 발명장치의 작용, 효과를 설명한다.Next, the operation and effect of the apparatus of the present invention constructed as described above will be described.

본 발명의 혈당측정장치(5)를 사용하려면, 먼저 측정자가 측정을 위해 센서스트립(1)를 스트립커넥터(2)에 삽입고정시킨다. 그리고 상기 혈당측정장치(5)의 키입력부(8)를 통해 상기 센서스트립(1)의 코드신호를 입력시켜주면 상기 혈당측정장치(5)의 단일화 모듈칩부(3)는 상기 센서스트립(1)의 코드신호를 인식하여 단일화 모듈칩부(3)에 저장된 정보내에서 검색하고 그 검색된 해당 센서스트립(1)의 동작전압을 생성하여 스트립커넥터(2)를 경유하여 해당 센서스트립(1)으로 출력시킨다. 따라서, 상기 센서스트립(1)은 단일화 모듈칩부(3)의 동작전압에 따라 최적의 엔자임반응을 가지고 혈당측정을 실행한다.In order to use the blood glucose measurement apparatus 5 of the present invention, the measurer first inserts the sensor strip 1 into the strip connector 2 for measurement. When the code signal of the sensor strip 1 is input through the key input unit 8 of the blood glucose measurement apparatus 5, the unitary module chip unit 3 of the blood glucose measurement apparatus 5 is connected to the sensor strip 1. Recognizes the code signal of the controller and searches within the information stored in the unitary module chip unit 3, generates the detected operating voltage of the corresponding sensor strip 1, and outputs it to the corresponding sensor strip 1 via the strip connector 2. . Therefore, the sensor strip 1 performs blood glucose measurement with an optimal enzyme response according to the operating voltage of the unitary module chip unit 3.

여기서, 상기 단일화 모듈칩부(3)는 도 5의 (a) 내지 (c)에 도시된 바와같이 제조사마다 각기 다른 센서스트립(1)의 최적동작에 맞는 다중전압을 생성하여 공급할 수 있게된다.       Here, as shown in (a) to (c) of FIG. 5, the unified module chip unit 3 can generate and supply multiple voltages for the optimal operation of the sensor strips 1 different for each manufacturer.

이 과정에서 상기 센서스트립(1)이 측정자의 채혈을 통해 혈당을 측정한 후 측정된 아날로그의 혈당 측정전류를 상기 단일화 모듈칩부(3)로 입력시키면, 상기 단일화 모듈칩부(3)는 해당 혈당 측정전류를 일정레벨로 증폭한 후 해당 혈당 측정전류를 분석처리한 후 (수학식 1)의 다차방정식형태의 오차보정절차를 통해 제조사마다 각기 다른 상기 센서스트립(1)의 전압대 혈당검출값에 따른 곡선형태의 측정오차를 도 4에 도시된 바와같이 보정해 준 다음 현재의 혈당측정치를 산출하여 디스플레이(4)상에 표시시키므로 측정자가 자신의 현재 혈당치를 정확하게 확인하게된다.       In this process, when the sensor strip 1 measures blood glucose through a blood collection of a measurer and inputs the measured analog blood glucose measurement current to the unified module chip unit 3, the unified module chip unit 3 measures the corresponding blood sugar level. After amplifying the current to a certain level and analyzing the corresponding blood glucose measurement current, the error correction procedure of the multi-order equation type (Equation 1) according to the voltage-to-blood glucose detection value of the sensor strip (1) different for each manufacturer The measurement error of the curved shape is corrected as shown in FIG. 4, and then the present blood glucose measurement value is calculated and displayed on the display 4, so that the measurer accurately confirms the current blood glucose level.

한편, 상기 과정중에 상기 단일화 모듈칩부(3)는 적외선검출센서(6) 혹은 IR센서를 통해 센서스트립(1)의 측정부(7)의 온도를 검출한다. 이때 상기 단일화 모듈칩부(3)는 상기와 같이 적외선검출센서(6)에 의해 검출된 온도검출값을 이용하여 현재 측정된 혈당측정치의 온도오차를 보정해주므로써 최적의 혈당측정을 실행한다.In the meantime, the unified module chip unit 3 detects the temperature of the measuring unit 7 of the sensor strip 1 through the infrared detection sensor 6 or the IR sensor. At this time, the unified module chip unit 3 performs the optimal blood glucose measurement by correcting the temperature error of the currently measured blood glucose measurement by using the temperature detection value detected by the infrared detection sensor 6 as described above.

1 : 센서스트립 2 : 스트립커넥터
3 : 단일화모듈칩부 4 : 디스플레이
5 : 혈당측정장치 6 : 적외선검출센서
7: 측정부 8 : 키입력부
9 : 전원공급부1: Sensor strip 2: Strip connector
3: unified module chip unit 4: display
5: blood glucose measurement device 6: infrared detection sensor
7: measuring unit 8: key input unit
9: power supply

Claims (6)

혈당측정장치의 외부몸체에 설치되고 센서스트립이 삽입고정되는 스트립커넥터와;
상기 센서스트립으로 설정된 측정전압을 공급하고 상기 센서스트립에 의해 검출된 혈당 측정전류를 증폭하고 상기 혈당 측정전류를 분석처리한 후 현재의 혈당측정치를 산출하는 단일화 모듈칩부와;
상기 단일화 모듈칩부에 의해 산출된 혈당측정치를 외부로 표시하는 디스플레이를 포함하는 것을 특징으로 하는 단일화모듈구성의 혈당측정장치.A strip connector installed on the outer body of the blood glucose measurement apparatus and having a sensor strip inserted therein;
A unified module chip unit for supplying the measurement voltage set to the sensor strip, amplifying the blood glucose measurement current detected by the sensor strip, analyzing the blood sugar measurement current, and calculating a current blood glucose measurement value;
And a display for displaying a blood glucose measurement value calculated by the unified module chip to the outside. 제1항에 있어서, 상기 단일화 모듈칩부는 마이컴, A/D 컨버터, LCD 드라이버, 아날로그 스위치, OP 앰프, 메모리부, 써미스터를 포함하여 하나의 반도체칩에 집적화하여 구성되는 것을 특징으로 하는 단일화모듈구성의 혈당측정장치.      The integrated module configuration of claim 1, wherein the integrated module chip unit is configured to be integrated into one semiconductor chip including a microcomputer, an A / D converter, an LCD driver, an analog switch, an OP amplifier, a memory unit, and a thermistor. Blood glucose measurement device. 제1항에 있어서, 상기 단일화 모듈칩부는 (수학식 1)의 다차방정식형태의 오차보정절차를 구비하여 제조사마다 각기 다른 상기 센서스트립(1)의 전압대 혈당검출값에 따른 측정오차를 보정해주는 것을 특징으로 하는 단일화모듈구성의 혈당측정장치.
[수학식 1]
혈당값 =
Figure pat00002

여기서, X: 바이오센서에서 측정한 uA 단위의 전류 측정값( 혈당 농도에 따라 반응 전류 값이 변함 ),
a, b, c, d, e, f : 전류값 변화를 혈당값 변화로 만든 수식 계산용 상수 값The method of claim 1, wherein the unified module chip unit has an error correction procedure in the form of a multi-order equation of Equation (1) to correct the measurement error according to the voltage vs. blood glucose detection value of the sensor strip (1) different for each manufacturer Blood sugar measuring device of the unitary module configuration, characterized in that.
[Equation 1]
Blood sugar level =
Figure pat00002

X is the current measurement value in uA measured by the biosensor (reaction current value changes according to blood glucose concentration),
a, b, c, d, e, f: constant value for calculating the formula that changes the current value into the blood sugar value 제1항에 있어서, 상기 단일화 모듈칩부는 제조사가 각기 다른 센서스트립의 코드신호를 인식한후 해당 센서스트립에 맞는 다중동작전압을 생성하여 해당 센서스트립에 공급시키는 것을 특징으로 하는 단일화모듈구성의 혈당측정장치.      According to claim 1, wherein the unified module chip unit after the manufacturer recognizes the code signal of the different sensor strips to generate a multi-operation voltage suitable for the corresponding sensor strip to supply to the corresponding sensor strip blood sugar Measuring device. 제1항에 있어서, 상기 단일화 모듈칩부는 18 bit의 A/D 컨버터기능을 내장하는 것을 특징으로 하는 단일화모듈구성의 혈당측정장치.      The blood glucose measurement apparatus of claim 1, wherein the unified module chip unit has an 18-bit A / D converter function. 제1항에 있어서, 상기 단일화 모듈칩부는 센서스트립에 구비된 측정부의 온도를 측정하여 단일화 모듈칩부로 입력시키는 적외선검출센서가 연결되는 것을 특징으로 하는 단일화모듈구성의 혈당측정장치.
According to claim 1, wherein the unified module chip unit blood glucose measurement apparatus of the unified module configuration, characterized in that the infrared detection sensor for measuring the temperature of the measuring unit provided in the sensor strip and input to the unified module chip unit.
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KR20190054361A (en) * 2017-11-13 2019-05-22 울산과학기술원 Apparatus and method for calibrating glucose level
US10627362B2 (en) 2014-07-31 2020-04-21 Samsung Electronics Co., Ltd Blood glucose measuring device and method, and electronic device including blood glucose measuring module

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US10627362B2 (en) 2014-07-31 2020-04-21 Samsung Electronics Co., Ltd Blood glucose measuring device and method, and electronic device including blood glucose measuring module
KR20190054361A (en) * 2017-11-13 2019-05-22 울산과학기술원 Apparatus and method for calibrating glucose level

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