KR20120075868A - Preparation method for the heat controlled phantom - Google Patents

Preparation method for the heat controlled phantom Download PDF

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KR20120075868A
KR20120075868A KR1020100137755A KR20100137755A KR20120075868A KR 20120075868 A KR20120075868 A KR 20120075868A KR 1020100137755 A KR1020100137755 A KR 1020100137755A KR 20100137755 A KR20100137755 A KR 20100137755A KR 20120075868 A KR20120075868 A KR 20120075868A
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South Korea
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temperature
simulated material
human tissue
simulated
phantom
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KR1020100137755A
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Korean (ko)
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정경렬
최준호
김사엽
손현목
박성빈
형준호
안양수
노종련
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한국생산기술연구원
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    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • G09B23/30Anatomical models
    • G09B23/303Anatomical models specially adapted to simulate circulation of bodily fluids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A61B5/015By temperature mapping of body part

Abstract

PURPOSE: A method for manufacturing a simulated material of human tissue is provided to simplify configuration of a system as compared with a forced circulation temperature control device by locating a heating element within a phantom. CONSTITUTION: A simulated material of human tissue is prepared(S110). The human tissue comprises a heating apparatus in inside. The simulated material of the human tissue is formed into a polygonal structure having three-dimensional volume. A temperature sensor is added in the simulated material(S120). The temperature sensor measures heating temperature of a tumor imitation body. A temperature controller is added in the simulated material(S130). The temperature controller regularly makes maintain the temperature of the simulated material.

Description

열원 제어가 가능한 인체조직의 모사 물질 제조방법{Preparation method for the heat controlled phantom}Method for manufacturing simulated material of human tissue that can control heat source {Preparation method for the heat controlled phantom}

본 발명은 인체내부의 온도를 측정하기 위한 마이크로파 라디어미터 연구에 활용하기 인체내부의 모사 조직에 관한 것이다.
The present invention relates to a simulated tissue in the human body for use in the study of microwave radiators for measuring the temperature in the human body.

깊은 생체조직에서 전자기 에너지의 일부가 피부로 전달되는데, 이때 생체 내부에서 피부로 전달되는 전자기 에너지의 세기는, 주파수 대역과 전자기파를 흡수, 반사, 투과시키는 인체의 매질에 따라 다르다. Microwave Radiometry는 인체 내부 조직에서 방출되는 1~6 GHz 대역의 전자기 에너지 일부를 피부 표면에서 측정하여 일정한 체적내의 인체 내부 온도 평균온도를 추정하는 방법이다. 이러한 Radiometry로 암이나 종양 등의 이상 조직을 진단하는 의학적 가설은, 암이 진행시 악성 종양의 세포의 신진대사가 정상 세포보다 활발하게 되고 또한 종양세포 주위로 혈액의 유입이 증가하게 되어, 주위의 정상세포 보다 열을 보다 더 방출하는데 있다. 이때 발생된 열은 일정한 주파수 대역의 마이크로파 에너지를 방출하게 되고, 이에 Radiometry로 인체에 무해하고(passive), 비침습적(non-invasive), 방사능의 영향이 없는 (non-ionizing) 방법으로 인체 내부에서 전달되는 전자기 에너지 강도를 측정하여 종양 부위와 주위 정상부위의 온도 차이를 추정 의학진단에 응용할 수 있다. In deep biological tissues, part of the electromagnetic energy is transmitted to the skin. The intensity of the electromagnetic energy transmitted from the inside of the living body to the skin depends on the frequency band and the medium of the human body that absorbs, reflects, and transmits electromagnetic waves. Microwave radiometry is a method of estimating the average internal temperature of a human body in a certain volume by measuring some of the electromagnetic energy in the 1-6 GHz band emitted from internal tissues on the skin surface. The medical hypothesis of diagnosing abnormal tissues such as cancer and tumors by radiometry is that when cancer progresses, the metabolism of cells of malignant tumors becomes more active than normal cells, and blood flow increases around tumor cells. To release more heat than normal cells. Heat generated at this time emits microwave energy of a certain frequency band, which is therefore harmless to the human body by radiometry (non-invasive) and non-ionizing method (radiation) inside the human body. By measuring the delivered electromagnetic energy intensity, the temperature difference between the tumor site and the surrounding normal site can be applied to the estimated medical diagnosis.

내부 온도를 측정하는 대상 매질이 단일 매일인 경우, 매질의 감쇄 정보를 예측하여 온도를 추정할 수 있으나, 복합 매질, 특히 인체의 경우, 사람마다 조직 특성이 다르기 때문에 정확한 내부 온도를 추정하는 데는 어려움이 있다.
If the target medium for measuring the internal temperature is a single daily, it is possible to estimate the temperature by estimating the attenuation information of the medium.However, in the case of a complex medium, especially a human body, it is difficult to estimate the accurate internal temperature because the tissue characteristics differ from person to person. There is this.

본 발명은 상기와 같은 문제점을 해결하기 위한 것으로 마이크로웨이브 라디오메터의 인체생리학적 특성을 파악하기 위한 열원 제어가 가능한 인체조직의 모사 물질 제조방법에 관한 것이다.
The present invention to solve the above problems relates to a method of manufacturing a simulated material of human tissue capable of controlling the heat source for grasping the physiological characteristics of the microwave radiometer.

상기와 같은 문제를 해결하기 위해 본 발명인 열원 제어가 가능한 인체조직의 모사 물질 제조방법은 입체적인 체적을 갖는 다각형 구조로 형성되고, 내부에 발열 장치가 구비된 인체조직의 모사 물질을 준비하는 단계; 상기 모사 물질에 온도센서를 부가하는 단계;및 상기 모사 물질의 온도를 일정하기 유지시키는 온도 컨트롤러를 부가하는 단계를 포함한다.In order to solve the above problems, the present invention provides a method of manufacturing a simulated material of the human tissue that can control the heat source is formed in a polygonal structure having a three-dimensional volume, preparing a simulated material of the human tissue having a heating device therein; Adding a temperature sensor to the simulated material; and adding a temperature controller to keep the temperature of the simulated material constant.

본 발명은 기존 팬텀의 온도를 제어하기 위한 발열체(heating element)를 팬텀안에 두어 기존 팬텀에서 이용되고 있는 강제순환식 온도조절 장치에 비해 시스템 구성을 단순화 하였다.
The present invention has a heating element for controlling the temperature of the existing phantom in the phantom to simplify the system configuration compared to the forced circulation type thermostat used in the existing phantom.

도 1은 본 발명에 따른 열원 제어가 가능한 인체조직의 모사 물질 제조방법의 블록도이다. 1 is a block diagram of a method for producing a simulated material of human tissue capable of controlling the heat source according to the present invention.

이하 첨부된 도면을 참조하여 본 발명이 속하는 기술분야에서 통상의 지식을 가진 자가 본 발명을 용이하게 실시할 수 있는 바람직한 실시 예를 상세히 설명한다. 다만, 본 발명의 바람직한 실시 예에 대한 동작 원리를 상세하게 설명함에 있어 관련된 공지 기능 또는 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우에는 그 상세한 설명을 생략한다. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. However, in describing in detail the operating principle of the preferred embodiment of the present invention, if it is determined that the detailed description of the related known function or configuration may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted.

또한, 도면 전체에 걸쳐 유사한 기능 및 작용을 하는 부분에 대해서는 동일한 도면 부호를 사용한다.In addition, the same reference numerals are used for parts having similar functions and functions throughout the drawings.

덧붙여, 명세서 전체에서, 어떤 부분이 다른 부분과 '연결'되어 있다고 할때, 이는 '직접적으로 연결'되어 있는 경우뿐만 아니라, 그 중간에 다른 소자를 사이에 두고 '간접적으로 연결'되어 있는 경우도 포함한다. 또한 어떤 구성 요소를 '포함'한다는 것은, 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라, 다른 구성요소를 더 포함할 수 있는 것을 의미한다.In addition, throughout the specification, when a part is 'connected' to another part, it is not only 'directly connected' but also 'indirectly connected' with another element in between. Include. In addition, the term 'comprising' a certain component means that the component may be further included, without excluding the other component unless specifically stated otherwise.

먼저, 도 1를 참조하여, 본 발명인 열원 제어가 가능한 인체조직의 모사 물질 제조방법을 설명한다.First, with reference to Figure 1, the present invention will be described a method of manufacturing a simulated material of human tissue capable of controlling the heat source.

도 1은 본 발명인 열원 제어가 가능한 인체조직의 모사 물질 제조방법을 나타내는 블록도이다. 1 is a block diagram showing a method for producing a simulated material of human tissue capable of controlling the heat source of the present invention.

먼저,입체적인 체적을 갖는 다각형 구조로 형성되고, 내부에 발열 장치가 구비된 인체조직의 모사 물질을 준비한다(S110).First, it is formed in a polygonal structure having a three-dimensional volume, and prepares a simulated material of human tissue having a heating device therein (S110).

상기 모사 물질은 일반적으로 젤라틴과 염화나트륨, 설탕 등을 배합하여 제조되며, 내부에 니크롬선 등의 발열체를 포함한다.The mimic material is generally prepared by mixing gelatin, sodium chloride, sugar, and the like, and includes a heating element such as nichrome wire therein.

다음으로, 상기 모사 물질에 온도센서를 부가한다(S120). 상기 인체 조직의 모사 물질의 표면에는 종양 모방자의 발열온도를 측정할 수 있는 온도센서를 위치시킨다.Next, a temperature sensor is added to the replica material (S120). On the surface of the mimic material of the human tissue is placed a temperature sensor capable of measuring the exothermic temperature of the tumor mimic.

그 다음으로, 상기 모사 물질의 온도를 일정하기 유지시키는 온도 컨트롤러를 부가한다(S130). Next, a temperature controller for maintaining a constant temperature of the simulated material is added (S130).

즉, 생체조직 모델을 위해 제작된 상기 모사 조직의 온도를 외부로 부터 원하는 온도로 유지할 수 있는 온도 컨트롤러를 부가한다. That is, a temperature controller for maintaining the temperature of the simulated tissue produced for the biological tissue model from the outside to a desired temperature is added.

이와 같이 , 열원 제어가 가능한 인체조직의 모사 물질 제조방법은 열원 조절 장치를 이용하여 상기 모사조직의 내부온도를 측정가능한바, 인체내부의 온도를 추정하는 모델링에 응용이 가능하다.
As described above, the method for manufacturing a simulated material of human tissue capable of controlling the heat source can measure the internal temperature of the simulated tissue using a heat source control device, and can be applied to modeling to estimate the temperature inside the human body.

Claims (1)

입체적인 체적을 갖는 다각형 구조로 형성되고, 내부에 발열 장치가 구비된 인체조직의 모사 물질을 준비하는 단계;
상기 모사 물질에 온도센서를 부가하는 단계;및
상기 모사 물질의 온도를 일정하기 유지시키는 온도 컨트롤러를 부가하는 단계를 포함하는 열원 제어가 가능한 인체조직의 모사 물질 제조방법.

Preparing a simulated material of human tissue formed in a polygonal structure having a three-dimensional volume and having a heating device therein;
Adding a temperature sensor to the replica material; and
Method of manufacturing a simulated material of human tissue capable of heat source control comprising the step of adding a temperature controller for maintaining a constant temperature of the simulated material.

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109935154A (en) * 2019-03-12 2019-06-25 中国原子能科学研究院 A kind of isotope heat source launching site fire smoldering test method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109935154A (en) * 2019-03-12 2019-06-25 中国原子能科学研究院 A kind of isotope heat source launching site fire smoldering test method

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