KR20110076690A - Drug control tube and drug control device using there of - Google Patents

Abstract

PURPOSE: A drug control tube and a drug control device using the same are provided to minutely control the amount of drug and to be inserted into a living body. CONSTITUTION: A drug control device comprises: a drug control tube(110) in which a first adhesion plate and a second adhesion plate are adhered to each other; in the form of the board which each other adheres closely to; an ultrasonic generating part(120) which generates ultrasonic wave; and a controller(130) controlling the ultrasonic generating part. The controller controls the size and times of the pulse of the ultrasonic wave and the frequency of the ultrasonic wave.

Description

Drug control tube and drug control device using the same {DRUG CONTROL TUBE AND DRUG CONTROL DEVICE USING THERE OF}

The present invention relates to a drug control tube and drug control device for adjusting the amount of drug injection so that a certain drug is injected into the living body.

Drugs are injected in a variety of ways, depending on the type of drug or the subject using the drug. Especially in the case of drugs for surgery or chemotherapy, the drug must be continuously injected for a certain period of time to control pain. As such, drug control devices are used as a means for continuously injecting drugs for a certain time.

However, in the conventional drug control device, it is difficult to precisely control the flow rate of the drug because it regulates the flow rate of the drug by applying pressure to the tube through which the drug is transferred using a roller or the like.

Accordingly, a technique for accurately adjusting the flow rate of the drug is disclosed through the Republic of Korea Patent No. 10-0472044 (name of the invention: drug injection amount control device) and the like.

However, the above-mentioned technology is to adjust the amount of the drug by using a control member for controlling the amount of the drug along a certain groove in order to continuously and constantly input the amount of the drug, such as Ringer's solution or special injection drug to be injected into the patient Therefore, it is not possible to control the amount of the drug more finely than the interval between the grooves, and to adjust the amount of drug by simply adjusting the amount of the drug according to the user's intention or visually confirming the amount of ringer solution, etc. The problem is that you can't control it correctly.

The present invention has been made in view of the above-mentioned problems, and has an object of providing a drug control tube and a drug control device using the same, the volume of which can be inserted into a living body and finely adjusts the amount of the drug.

In one aspect of the present invention, a drug control device comprises: a drug control tube made of a plate in which a first contact surface and a second contact surface are in close contact with each other; An ultrasonic wave oscillator for oscillating ultrasonic waves so that a gap through which drugs can pass is formed between the first and second contact surfaces; And a control unit for controlling the ultrasonic oscillator; Characterized in that it comprises a.

In addition, the control unit is characterized in that for controlling the gap that can pass the drug to control the size of the pulse (pulse) of the ultrasonic wave oscillated by the ultrasonic wave oscillator.

The controller may control the number of pulses of the ultrasonic wave oscillated by the ultrasonic wave oscillator to adjust the gap through which the drug may pass.

The controller may control the frequency of the ultrasonic wave oscillated by the ultrasonic wave oscillator to adjust the gap through which the drug may pass.

And frame coupled to the outer surface of the first contact surface of the drug control tube for supporting the contact portion; Further comprising, the ultrasonic wave is characterized in that applied to the second contact surface.

In addition, the acoustic impedance of the first contact surface and the second contact surface (acoustic impedance) is characterized in that different from each other.

And the drug control tube is characterized in that the first inlet and the second intimate surface is in close contact with each other the inlet of the drug inlet is formed, the outlet of the drug outlet is formed on the other side of the plate is formed do.

In addition, the pressure measuring unit for measuring the pressure difference between the inlet and the outlet; It further comprises, The control unit is characterized in that for controlling the ultrasonic oscillator in accordance with the results measured by the pressure measuring unit to adjust the flow rate of the drug (流 量).

In addition, a portable power supply for supplying AC power to the ultrasonic oscillator; It characterized in that it further comprises.

And a communication unit for exchanging information with an external terminal; It characterized in that it further comprises.

The external terminal may provide a control signal for controlling the ultrasonic wave oscillator to the controller through the communication unit according to the information provided from the communication unit.

The communication unit may exchange information with the external terminal using a radio frequency (RF) signal or an infrared ray (IR) signal.

In addition, the auxiliary transport pipe for continuously transporting the drug over a certain amount; It characterized in that it further comprises.

And a display unit for displaying whether the drug leaked out and the operating state of the ultrasonic wave oscillator; It characterized in that it further comprises.

On the other hand, the drug control tube according to one aspect of the present invention to achieve this object is the inlet to which the drug is introduced; An outlet portion through which the drug flows out; And a first contact surface and a second contact surface formed in close contact with each other, one side of which is coupled to the inlet, and the other side of the contact to which the outlet is coupled; It includes, wherein the close portion is characterized in that the gap is formed to pass the drug by the ultrasonic wave.

In addition, the frame coupled to the outer surface of the first contact surface of the contact portion to support the contact portion; Further comprising, the ultrasonic wave is characterized in that applied to the second contact surface.

And the acoustic impedance of the first contact surface and the second contact surface (acoustic impedance) is characterized in that different.

In addition, the close contact portion is characterized in that the gap through which the drug is passed according to the size of the pulse (pulse) of the ultrasonic wave is formed differently.

And the close contact portion is characterized in that the gap that can pass the drug is formed differently according to the number of pulses (pulse) of the ultrasound.

In addition, the close contact portion is characterized in that the gap through which the drug is passed according to the frequency of the ultrasonic wave is formed differently.

As described above, according to the present invention, since the drug passes through the micro-gaps formed on the contact surface using ultrasonic waves, the effect of increasing the efficacy of the drug by precisely controlling the amount of the drug injected for a predetermined time to the microunit is improved. have.

In addition, the ultrasonic wave is used to form a gap that allows the drug to pass between the contact surfaces, thereby minimizing the effect on the living body.

In addition, since the gap that allows the drug to be passed by the control unit by using the ultrasonic wave has the effect of providing the correct amount of drug.

In addition, by controlling the gap through which the drug can be passed by the control unit by using ultrasonic waves, the movement speed of the drug is kept constant, and the effect of preventing the side effects caused by sudden inflow of a large amount of the drug is introduced. have.

DETAILED DESCRIPTION OF THE INVENTION Preferred embodiments of the present invention will be described in more detail with reference to the accompanying drawings, which will be omitted or condensed for the sake of brevity.

The drug injection device according to the present invention relates to a technique for automatically and precisely adjusting the amount of drug injected to a fine unit for a predetermined time, which will be described with reference to the drawings shown in FIGS. 1 to 6.

Drug control device 100 according to the invention drug control tube 110, ultrasonic oscillator 120, control unit 130, resistance unit 140, pressure measuring unit 150, portable power supply unit 160, communication unit 170, the auxiliary transport pipe 180, and the display 190 are formed.

Drug control tube 110 is a place for precisely adjusting the amount of drug to be injected for a predetermined time to a fine unit, and includes an inlet 111, outlet 112, close contact portion 113 and the frame 114 and the like. It is done by

Inlet 111 is coupled to one side of the close portion 113 is a place where the drug is introduced can be made in any form if the drug can be introduced in the form of a cylinder, such as a ringer tube and blood vessel It is preferable. The inlet 111 is biocompatible to prevent risks such as inflammation and tissue destruction that may occur due to contact with tissue and blood after transplanting the drug control tube 110 according to the present invention. It is preferred to be made of excellent polymers, silicones and the like.

Outlet 112 is coupled to the other side of the close portion 113 is a place where the drug passed through the close portion 113 is discharged. Description of the shape and material of the outlet 112 is the same as the inlet 111 and omitted.

The close contact portion 113 has a form in which the first contact surface 113a and the second contact surface 113b are in close contact with each other, one side is coupled to the inlet 111, and the other is coupled to the outlet 112. do. The close contact portion 113 may be a gap that can pass the drug by the ultrasonic wave in a state of being completely in contact.

That is, when ultrasonic waves are irradiated to the first contact surface 113a and the second contact surface 113b, which are completely in contact with each other so that the drug cannot pass, between the first contact surface 113a and the second contact surface 113b. Gaps may be formed that allow the drug to pass through.

At this time, the first contact surface 113a and the second contact surface 113b are made of a material having different acoustic impedances, and the first contact surface 113a and the second contact surface 113b by ultrasonic waves. A gap may be formed between the gaps.

That is, the acoustic impedance is a value obtained by dividing the sound pressure of each minute portion of the medium through which the sound wave is transmitted by the product of the vibration speed of the sound wave and the area parallel to the wavefront of the sound wave. The second contact surface 113b may generate a difference in the vibration speed by ultrasonic waves, such that a gap such as a gap may occur between the first contact surface 113a and the second contact surface 113b.

The adhesion part 113 may have different gaps through which drugs may be passed depending on how the at least one of the size of the pulse, the number of pulses, and the frequency of the ultrasound changes.

In addition, when irradiating the ultrasonic pulse of a large output to the 1st contact surface 113a and the 2nd contact surface 113b, the energy of a sound wave is the boundary surface of the 1st contact surface 113a and the 2nd contact surface 113b. Accumulated and, through this, cavitation is induced between the first contact surface 113a and the second contact surface 113b to form a gap through which the drug can pass.

On the other hand, the inlet 111, the outlet 112 and the close portion 113 may be made separately and combined respectively, but in order to save the manufacturing cost inlet 111, outlet 112 and It is preferable that the close contact portion 113 is manufactured in one piece.

The frame 114 is coupled to the outer surface of the first contact surface 113a of the contact part 113 to support the contact part 113.

In addition, the frame 114 reflects the ultrasonic waves applied to the second contact surface 113b. That is, the frame 114 reflects the ultrasonic waves to minimize the effect of the ultrasonic waves applied to the second contact surface 113b side through the second contact surface 113b and the first contact surface 113a to minimize the effect on the living body.

The frame 114 may be any material capable of supporting the close contact portion 113 and reflecting ultrasonic waves, but may be caused by contact with tissues and blood after transplantation, such as inflammation and tissue destruction. In order to prevent a danger, it is preferable that it is made of a metal having excellent biocompatibility.

The drug control tube 110 may be manufactured in various sizes to control the amount of the drug, but may be finely manufactured so that it can be used in small size tubes used in lab on a chip. .

The following describes the operating state of the drug control tube 110 with reference to FIG.

When the first contact surface 113a and the second contact surface 113b are in close contact with each other and the ultrasound is applied to the second contact surface 113b in a state in which the transport of drugs is blocked, the first contact surface 113a and the first contact surface 113a and the second contact surface 113b are closed. Due to the difference in acoustic impedance of the two contact surfaces 113b, a gap is formed between the first contact surface 113a and the second contact surface 113b.

Then, the drug introduced into the inlet 111 through the gap formed between the first contact surface 113a and the second contact surface 113b passes through the contact portion 113 and flows out through the outlet 112.

The ultrasonic oscillator 120 oscillates the ultrasonic wave so that a gap through which the drug can pass is formed between the first contact surface 113a and the second contact surface 113b, and various ultrasonic waves under the control of the controller 130. Oscillate. In addition, the ultrasonic oscillator 120 may be supplied with power from the outside to oscillate ultrasonic waves, but is preferably implanted into a living body to receive power from the portable power supply unit 150 to oscillate ultrasonic waves.

The ultrasonic oscillator 120 may oscillate ultrasonic waves using a piezoelectric element exhibiting a piezoelectric phenomenon or an element vibrating by an alternating magnetic field generated from a coil.

The controller 130 is composed of a CPU and the like to control the ultrasonic oscillator 120, to control the various states of the ultrasonic wave oscillated in the ultrasonic oscillator 120 to adjust the gap that can pass the drug, but the pulse ( At least one of the magnitude of the pulse, the number of pulses, and the frequency is preferably controlled.

In addition, the controller 130 controls the pressure measuring unit 150 and controls the ultrasonic oscillation unit 120 generating ultrasonic waves according to the result provided from the pressure measuring unit 150 to adjust the flow rate of the drug.

In addition, the controller 130 provides information on whether the drug is leaked and the operating state of the ultrasonic oscillator 120 to the communication unit 160 and ultrasonic waves according to the control signal received through the communication unit 160 from the external terminal T. The oscillator 120 is controlled.

In addition, the controller 130 controls the display 190.

Through such a control unit 130 can be finely adjusted the flow rate of the drug automatically.

The resistance unit 140 is a place for adjusting the flow rate of the drug that is transferred to the gap formed by the ultrasonic wave oscillator 120. The shape of the resistance unit 140 may be formed in any form as long as it can adjust the flow rate, but preferably made of a clamp (Clamp) that can conveniently adjust the flow rate of the drug control tube (110).

In addition, the resistance unit 140 may be installed anywhere of the drug control device 100 according to the present invention if the flow rate can be adjusted, but is installed on the inlet 111 side into which the drug is introduced to adjust the flow rate of the drug. It is desirable to.

On the other hand, since the resistance unit 140 regulates the flow rate of the drug, a strong pressure is applied to the adhesion unit 113 by the drug transported through the inlet 111 that is relatively bulky compared to the adhesion unit 113. Can be prevented.

The pressure measuring unit 150 is a place for measuring the pressure difference between the inlet 111 and the outlet 112. The pressure measuring unit 150 may be made of any one as long as it can measure the pressure difference between the inlet 111 and the outlet 112, but a pressure sensor for measuring the pressure of the drug control tube 110. It is preferable to include such as.

In addition, the pressure measuring unit 150 detects the pressure of the inlet 111 and the outlet 112 to measure the pressure difference between the inlet 111 and the outlet 112 and the measured results of the controller 130 ) To the side.

Next, the pressure is measured through the pressure measuring unit in more detail, but for convenience of understanding, as shown in the circuit diagram of FIG. 140) and the portion that directly controls the flow rate of the drug, such as the ultrasonic oscillator 120 will be described by replacing the resistance of the circuit.

Where Vin is the pressure of the drug flowing into the drug control device 100 to the voltage of the circuit diagram, V1 is a circuit diagram of the pressure of the drug flowing between the first contact surface (113a) and the second contact surface (113b) It is replaced by the voltage of. In addition, Vout is to replace the pressure of the drug flowing out through the outlet 112 with the voltage of the circuit diagram, wherein the pressure of the drug flowing out through the outlet 112, such as the ground of the circuit to measure the pressure of the drug It was set as standard for.

In addition, R is to replace the resistor 140 with the resistance of the circuit diagram, Rx is to replace the ultrasonic oscillator 120 with the variable resistor of the circuit diagram.

At this time, the voltage Vin passes through the resistor R, and a voltage drop occurs, and the voltage V1 lowered according to Ohm's law passes through the resistor Rx, and a voltage drop occurs once again.

That is, Vin is a voltage drop is generated while passing through R and Rx and the pressure of the drug flowing into the drug control device 100 according to the present invention is reduced through the drug measuring unit and the ultrasonic oscillator 120.

As such, the pressure of the drug flowing into the drug control device 100, the pressure of the drug flowing between the first contact surface 113a and the second contact surface 113b, the drug of the drug flowing through the outlet 112 The relationship between the pressure, the resistance unit 140 and the ultrasonic wave oscillator 120 is given by Equation 1.

As such, in order to detect whether a gap for passing the drug is formed by the ultrasonic wave generator 120, the pressure measuring unit 150 is connected in parallel with the drug control tube 110.

At this time, when the drug control tube 110 is in close contact with the drug cannot pass, the pressure difference (Vin-V1) at both ends of the resistance unit 140 is formed low and the pressure difference (V1-) at both ends of the drug control tube (110). Vout) is formed high.

In addition, when a gap is formed in the drug control tube 110 to pass the drug, the pressure difference (Vin-V1) at both ends of the resistance unit 140 is formed high and the pressure difference (V1-) at both ends of the drug control tube (110). Vout) is formed low.

That is, it can be seen whether or not a gap is formed through the drug control tube through the V1.

In addition, when Vin, R, and Rx can be known, since the V1 can be directly calculated and predicted without measuring V1 through the pressure measuring unit 150, the controller 130 may oscillate through the ultrasonic oscillator 120. The ultrasonic wave oscillator 120 may be controlled by predicting the state of the ultrasonic waves.

Thus, the pressure difference between the both ends of the drug control tube 110 is formed differently depending on whether a gap is formed in the drug control tube 110, and can use the phenomenon to pass the drug or control the flow rate of the drug.

In addition, the pressure of the drug flowing into the drug control device 100, the pressure of the drug flowing between the first contact surface 113a and the second contact surface 113b, the pressure of the drug flowing through the outlet 112 The relationship between the resistance unit 140, the ultrasonic wave unit 120, and the flow rate of the drug is given by Equation 2.

If you do not know Vin, which is the pressure of the drug flowing into the drug control device 100, if Rx and R were measured in advance, it is possible to obtain Vin from V1 measured through the pressure measuring unit 150 and measure the flow rate of the drug I. It is possible to.

The controller 130 may control the ultrasonic oscillator 120 by adjusting the state of various ultrasonic waves oscillated through the ultrasonic oscillator 120 according to the measured flow rate of the drug.

That is, the pressure of the drug acting on the first contact surface 113a and the second contact surface 113b is determined by the pressure introduced into the drug control device 100, the resistance unit 140, and the ultrasonic wave oscillator 120. Through this relationship, the flow rate of the drug flowing out through the outlet 112 can be adjusted.

The portable power supply unit 160 is a place for supplying AC power to the ultrasonic wave oscillator 120. The portable power supply unit 160 may be any type as long as it supplies AC power to the ultrasonic oscillator 120 like a battery.

The communication unit 170 exchanges information with the external terminal T, and receives information on whether the drug is leaked and the operating state of the ultrasonic wave oscillator 120 from the control unit 130 to the external terminal T. And transmits the information received through the external terminal T to the controller 130.

In this case, the external terminal T provides a control signal for controlling the ultrasonic wave generator 120 to the controller 130 through the communication unit 170 according to the information provided from the communication unit 170.

That is, the drug control device 100 according to the present invention is controlled by the control unit 130 or in accordance with a control signal provided through the external terminal (T).

The communication unit 170 may use various communication technologies such as Bluetooth, Wireless LAN, etc., but exchanges information with an external terminal T using an RF (Radio Frequency) signal or an IR (Infrared Ray) signal. It is desirable to.

The auxiliary transport pipe 180 is a place for continuously transporting a predetermined amount or more of the drug, so that the drug flowing into the drug control tube 110 flows out without passing through the first contact surface 113a and the second contact surface 113b. The drug control tube 110 is connected in parallel. A constant flow rate may be generated even when power is not supplied to the ultrasonic wave generator 120 through the auxiliary transport pipe 180, and a higher flow rate may be generated when power is supplied to the ultrasonic wave generator 120.

In addition, the auxiliary transport pipe 180 may be made with a constant resistance to control the flow rate of the drug passing through the auxiliary transport pipe 180. That is, the auxiliary transport pipe 180 may adjust the flow rate of the drug passing through the auxiliary transport pipe 170 by adjusting the resistance value.

The display 190 is a place for displaying whether the drug is leaked and the operating state of the ultrasonic oscillator 120. The display unit 190 includes display means such as a light emitting diode, a display panel, or a CRT display (Cathode Ray Tube Display).

Accurate drug injection can be guided based on information such as whether the drug is displayed through the display 190 and the operating state of the ultrasonic wave oscillator 120. In addition, there is an advantage that can determine whether the failure of the drug control device 100 according to the present invention based on the information displayed through the display 190.

As described above, the detailed description of the present invention has been made by the present invention with reference to the accompanying drawings. However, since the above-described invention has only been described by way of example, the present invention is understood to be limited to the above invention. The scope of the invention should be understood by the claims and equivalent concepts described below.

1 is a block diagram of a drug control device according to the present invention.

Figure 2 is a perspective view of the drug control tube according to the present invention.

3 is a cross-sectional view of the drug control tube according to the present invention cut into the cross-sectional view taken along line X-X '.

Figure 4 is a simplified diagram showing a part of the drug control device according to the present invention.

Figure 5 is a simplified diagram showing another form of part of the drug control device according to the present invention.

Figure 6 is a circuit diagram substituted for explaining the pressure measuring method of the drug control device according to the present invention.

<Explanation of symbols for the main parts of the drawings>

100: drug control device

110: drug control tube

111: inlet 112: outlet

113: close contact

113a: first contact surface 113b: second contact surface

114: frame

120: ultrasonic wave oscillator 130: control unit

140: resistance unit 150: pressure measuring unit

160: portable power supply unit 170: communication unit

180: auxiliary transport pipe 190: display unit

T: external terminal

Claims (20)

Drug control tube formed in the form of a plate in which the first contact surface and the second contact surface is in close contact with each other; An ultrasonic wave oscillator for oscillating ultrasonic waves so that a gap through which drugs can pass is formed between the first and second contact surfaces; And A controller for controlling the ultrasonic oscillator; Characterized in that it comprises Drug control device. The method of claim 1, The control unit controls the size of the pulse of the ultrasonic wave (pulse) is oscillated by the ultrasonic wave oscillator to adjust the gap that can pass the drug. Drug control device. The method of claim 1, The control unit controls the number of pulses of the ultrasonic wave oscillated by the ultrasonic wave oscillator to adjust the gap that can pass the drug. Drug control device. The method of claim 1, The control unit controls the frequency of the ultrasonic wave oscillated by the ultrasonic wave oscillator to adjust the gap that can pass the drug. Drug control device. The method of claim 1, A frame coupled to an outer surface of the first contact surface of the drug control tube to support the contact portion; Further comprising: The ultrasonic wave is applied to the second contact surface Drug control device. The method of claim 1, The acoustic impedance of the first contact surface and the second contact surface (acoustic impedance) is characterized in that different Drug control device. The method of claim 1, The drug control tube is characterized in that the first inlet and the second intimate surface is in close contact with each other the inlet port for the drug is introduced, the outlet of the drug outlet is formed on the other side of the plate is formed doing Drug control device. The method of claim 7, wherein A pressure measuring unit measuring a pressure difference between the inlet and the outlet; More, The control unit controls the ultrasonic wave oscillator according to the result measured by the pressure measuring unit, characterized in that for adjusting the flow rate of the drug (流 量) Drug control device. The method of claim 1, A portable power supply unit supplying AC power to the ultrasonic wave oscillator; Characterized in that it further comprises Drug control device. 10. The method of claim 9, Communication unit for exchanging information with an external terminal; Characterized in that it further comprises Drug control device. The method of claim 10, The external terminal may provide a control signal for controlling the ultrasonic wave oscillator to the controller through the communication unit according to the information provided from the communication unit. Drug control device. The method of claim 10, The communication unit may exchange information with the external terminal using a radio frequency (RF) signal or an infrared ray (IR) signal. Drug control device. The method of claim 1, An auxiliary transport pipe for continuously transporting the drug over a predetermined amount; Characterized in that it further comprises Drug control device. The method of claim 1, A display unit which displays whether the drug is leaked and an operating state of the ultrasonic wave oscillator; Characterized in that it further comprises Drug control device. An inlet for introducing a drug; An outlet portion through which the drug flows out; And A first contact surface and a second contact surface formed in close contact with each other, one side of which is coupled to the inlet, and the other side of the contact to be coupled to the outlet; Including; The close contact portion is characterized in that the gap is formed to pass the drug by ultrasound. Drug Control Tube. The method of claim 15, A frame coupled to an outer surface of the first contact surface of the contact part to support the contact part; Further comprising: The ultrasonic wave is applied to the second contact surface Drug Control Tube. The method of claim 15, The acoustic impedance of the first contact surface and the second contact surface (acoustic impedance) is characterized in that different Drug Control Tube. The method of claim 15, The close contact portion is characterized in that the gap through which the drug is passed according to the size of the pulse (pulse) of the ultrasonic wave is formed differently Drug Control Tube. The method of claim 15, The close contact portion is characterized in that the gap through which the drug is passed according to the number of pulses (pulse) of the ultrasonic wave is formed differently Drug Control Tube. The method of claim 15, The close contact portion is characterized in that the gap that can pass the drug is formed differently according to the frequency of the ultrasonic wave Drug Control Tube.

Images