KR20110059203A - Composition for disinfection containing chlorine dioxide - Google Patents
Composition for disinfection containing chlorine dioxide Download PDFInfo
- Publication number
- KR20110059203A KR20110059203A KR1020090115857A KR20090115857A KR20110059203A KR 20110059203 A KR20110059203 A KR 20110059203A KR 1020090115857 A KR1020090115857 A KR 1020090115857A KR 20090115857 A KR20090115857 A KR 20090115857A KR 20110059203 A KR20110059203 A KR 20110059203A
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- KR
- South Korea
- Prior art keywords
- chlorine dioxide
- composition
- benzalkonium chloride
- disinfecting
- disinfection
- Prior art date
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/25—Rooms in buildings, passenger compartments
Abstract
Description
The present invention relates to chlorine dioxide compositions having bactericidal and disinfecting efficacy.
Recently, pandemic and sterilization is taking a notch for people around the world due to the recent influenza influenza. However, due to pollution of water quality and ecological environment, unlike the past, the incidence of diseases caused by bacteria and viruses such as group food poisoning is increasing year by year. have. In recent years, food poisoning accidents have increased by more than 100% compared to 2006, which is gradually increasing in size and grouping. It is natural that the inevitable reality of deterioration of water quality is the cause behind this phenomenon. The virus detection rate of Korean water supplies reaches 30-40%, and the groundwater pollution is severely disproved.
On the other hand, the cooling tower, which is an industrial facility, has also detected legionella in about 20% of cooling towers as the use of summer air conditioners increases.Avian influenza (AI) has been found in agriculture and livestock due to the lack of sterilization, disinfection and disinfection methods. Livestock diseases are spreading frequently.
The hygiene of ordinary homes and restaurants is no exception, and the reality is that they are not free from the enormous bacterial threat. However, indiscriminate or excessive use of disinfectants can cause environmental pollution. Therefore, in the present invention, by developing a sterilizing and disinfectant composition mainly composed of environmentally friendly chlorine dioxide, and widely used, it is necessary to prevent viruses or bacterial diseases such as swine flu.
It is already known that chlorine (Cl 2 ) has been used almost exclusively for sterilization and disinfection worldwide. The reality was that chlorine disinfectants were the most economical drug. However, disinfection by-products (DBPs), which are recently produced as a by-product of chlorine disinfection, include haloacetic acid (HAAs) and halo acetic acid (Thalometanes (THMs)). In addition to the hazardous substances that are strictly regulated in tap water, such as acetonitrile (HANs) and catcher chloral (Hloral Hydrate), a number of compounds are being released, and the dangers are becoming known. Nevertheless, the use of the so-called chlorine-based sodium hypochlorite (tea salt), known as "lax," which releases the same harmful compounds as disinfection by-products, has led to the false recognition that they are not simply chlorine, which has led many similar products to the disinfection market. It is also true that the mainstream has formed.
On the other hand, although ozone and ultraviolet (UV) have been spotlighted as non-chlorine disinfection means, this also has been reported in the market as it is known that the harmfulness caused by the production of by-products from disinfection is serious, not to mention the excessive device price. There is a rapid exit.
In particular, ozone generates numerous harmful disinfection by-products such as chlorates, iodates, bromates, hydrogen peroxides, epoxys and ozones. Because of this, its severity is known, and the representative one is bromate, known as a carcinogen. This bromate is strictly regulated to 0.01 ppm in Korea's water quality standards, and this substance has recently been detected in drinking water, which is living water, and has exceeded the standard.
In addition, sodium hypochlorite, well known as lax, has been widely marketed as a cleaning, disinfecting and disinfectant in the real world, but as mentioned above, it emits various harmful compounds such as chlorine, which causes respirators during or after use. Choking accidents, such as difficulty is constantly.
Chlorine Dioxide (ClO 2 ), which has been widely used as an eco-friendly disinfectant and disinfectant while strongly replacing the chlorine disinfectant in developed countries for many years, can be said to be an alternative to the disinfectant and disinfectant. As shown in [Table 1], this chlorine dioxide is also compared to the disinfection by-products of various sterilization and disinfectants, which were released in 2000 by the International Program on Chemical Safety (IPCS) under the World Health Organization (WHO). By the way, it can be said that the material proved to be excellent.
Organic compounds
Organic compounds
Halo Acetic Acid (HAA)
Haloacetonitrile (HAN)
Catcher Chloral
Chlorpicnyl Chlorphenol
N-chloramine
Haloplanon
Blomohydrin
(When using flame)
Cyanocanolic acid
Alkanoic acid
benzene
Carboxylic acid
chlorate
Cyanogen Chloride
Organic chloramine
Chloramino Acid
Chloral Carb
Haloketone
nitrite
chlorate
Hardazine
Ketone
Monobromoacetic acid
Dibromoacetic acid
Dibromer Acetone
Cyanogen bromide
Iodide
Bromate
Hydrogen peroxide
Hypobromus Mountain
Epoxy
Ozone Eight
Keto acid
Ketone
Carboxylic acid
[Source: WHO | IPCS, International Program on Chemical Safety]
As such, it has been proven to be the most ideal sterilization and disinfection method to date, and it has been applied to Niagara Falls (New York) water treatment facilities for the first time in the US in 1944. The Environmental Protection Agency (EPA) recommends detailed uses and applications for use in a wide range of areas, from drinking water to agricultural, commercial and industrial facilities, swimming pools and residential facilities. Approved for use as a disinfectant and disinfectant. This is because it is a water-soluble oxidant, there is no generation of carcinogens due to by-products, and because it has an environmentally friendly characteristic that is easily decomposed by light, the use of chlorine disinfectant is expanding rapidly.
Chlorine Dioxide (ClO 2 ) is 2.5 times stronger than chlorine disinfectant, so it has strong sterilization, disinfection, discoloration and deodorization effect. It is known to be the most effective disinfectant and disinfectant to remove spores (such as anthrax). In addition, the strong oxidizing power of iron, manganese, cyanide, phenol, such as heavy metals removal function is possible to improve the taste of water, and has a dioxin reduction ability of more than 98% compared to chlorine. In general, chlorine dioxide has a good pH reactivity with no increase in pH, whereas chlorine dioxide has a sterilizing and disinfecting effect rapidly as the pH is increased. Therefore, it can be a very useful disinfectant and disinfectant in cooling towers where pH control is difficult.
In addition, in terms of selectivity, chlorine dioxide rarely reacts with organic matter in highly contaminated water, and selectively destroys pollutants. In terms of sustainability, chlorine overwhelms chlorine as a means of inhibiting bacterial regrowth after disinfection. It is an important reason to emerge as a disinfectant and disinfectant.
In addition, chlorine dioxide has a very strong property of penetrating into the biomass (Biomass) is excellent in the removal of the biofilm (Biofilm) because it can suppress the removal of water (Slime) or inhibit anaerobic bacteria. In addition, toxicological tests of humans and animals on chlorine dioxide or very few by-products of chlorine dioxide or chlorine, resulting from disinfection, have been conducted over the years by the World Health Organization (WHO). It is officially proved to be non-hazardous at high concentrations (see WHO Document, Chlorite and Chlorate in Drinking Water, 2005).
In relation to the excellent disinfection and disinfection of chlorine dioxide, a number of experimental papers are published at home and abroad. Staphylococcus aureus, Salmonella, which are called essentials of Hazard Analysis and Critical Control Point (HACCP), In addition to E. coli, rapid removal of O157, sterilization, sterilization of fruit and vegetable aquatic products, and maintenance of freshness, Japan's Taiko Pharmaceutical Research Institute also released a study that chlorine dioxide prevents AI virus.
The second advantage of chlorine dioxide is that it is the safest way to prevent food hygiene accidents such as food poisoning and maintain the freshness of food, because it has excellent persistence of disinfection and removal of biofilm.
The reason why such excellent disinfectant and disinfectant disinfectant chlorine dioxide has not been widely used in the meantime has been the inconvenience that chlorine dioxide itself has a strong change in aging and has to be produced and used immediately on site. This was inevitably causing limitations in market adaptability. Due to such market characteristics, companies in Germany and the United States, which have developed related technologies, have developed and marketed "chlorine dioxide generators" in their own way, but they are difficult to miniaturize. Because it had a situation that was not able to respond immediately to the market required. Recently, as the problem of miniaturization technology is solved to some extent, the market is gradually spreading around the world, but the market penetration is still below the expectations of the company because it is still expensive. In particular, in Korea, most of the chlorine dioxide generators are imported from abroad, such as Germany, and demand has been raised steadily, but the market has not been full-scale since the price burden on consumers is increasing. It was true.
Therefore, the present inventors have repeatedly studied to invent a composition that can sterilize and disinfect bacteria and viruses in a more effective and environmentally friendly way, the main ingredient is chlorine dioxide, benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride As a secondary ingredient, benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride are added to the sterilization and disinfection power of chlorine dioxide to enhance sterilization and disinfection power and to make the surface active, so that chlorine dioxide can effectively penetrate skin, bathroom tiles, walls, etc. The present invention was completed by confirming the excellent efficacy.
It is an object of the present invention to provide a sterilizing or disinfecting composition comprising chlorine dioxide, benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride.
In order to achieve the above object, the present invention provides a sterilizing or disinfecting composition comprising chlorine dioxide, benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride.
The present invention also provides a composition for sterilizing or disinfecting water in which benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride are added in an amount of 0.1 to 0.2%, respectively, in an aqueous solution of 1800 to 2200 ppm of chlorine dioxide.
The present invention also provides a composition for disinfecting or disinfecting air or hands in which benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride are added in an amount of 0.1 to 0.2%, respectively, in an aqueous solution of 20 to 40 ppm of chlorine dioxide.
In addition, the present invention also sterilizes or disinfects water comprising treating the water with a composition comprising 1800-2200 ppm of chlorine dioxide, 0.1-0.2% of benzalkonium chloride, and 0.1-0.2% of dodecyl diaminoethyl glycine hydrochloride. Provide a way to.
The present invention also provides an air or hand comprising treating a composition comprising 20 to 40 ppm chlorine dioxide, 0.1 to 0.2% benzalkonium chloride, and 0.1 to 0.2% dodecyl diaminoethyl glycine hydrochloride It provides a method for sterilizing or disinfecting.
Compositions in which benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride are added to chlorine dioxide according to the present invention exhibit significant sterilization and disinfection ability compared to conventional chlorine dioxide. By activating to increase penetration, the composition can be usefully used as a disinfectant and a disinfectant.
Hereinafter, the present invention will be described in detail.
The present invention provides a sterilizing or disinfecting composition comprising chlorine dioxide (Clorine Dioxide, ClO 2 ), benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride.
The composition may be prepared by adding benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride, called Tego, to a concentration of 0.15%, respectively, in an aqueous solution of chlorine dioxide at a concentration of 2,000 ppm, but is not limited thereto.
In addition, the composition may be prepared by adding dodecyl diaminoethyl glycine hydrochloride, called benzalkonium chloride and Tego, to a concentration of 0.15% in an aqueous solution of chlorine dioxide at a concentration of 30 ppm, but is not limited thereto.
The composition according to the present invention has chlorine dioxide as a main component, and benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride as secondary components to add benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride to the sterilization and disinfection power of existing chlorine dioxide. As a result, it is possible to increase the penetration of the chlorine dioxide by reinforcing sterilization and disinfection.
In the present invention, in order to determine the bactericidal effect of various strains of the composition according to the present invention (E. coli, Pseudomonas aeruginosa, Salmonella, Shigella, Staphylococcus aureus), after mixing the composition of the present invention to the test strain suspension and reacted The number of viable cells was measured by time. As a result, the composition of the present invention was confirmed to exhibit a strong effect of removing 100% even in a 10 seconds response to various strains (E. coli, Pseudomonas aeruginosa, Salmonella, Shigella, Staphylococcus aureus) (Table 2, and Figure 1). To FIG. 5).
The present invention also provides a composition for sterilizing or disinfecting water in which benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride are added in an amount of 0.1 to 0.2%, respectively, in an aqueous solution of 1800 to 2200 ppm of chlorine dioxide.
The present invention also provides a method for disinfecting water comprising treating a water composition comprising 1800-2200 ppm chlorine dioxide, 0.1-0.2% benzalkonium chloride, and 0.1-0.2% dodecyl diaminoethyl glycine hydrochloride. Provide a way to disinfect.
The composition according to the present invention can be prepared for sterilization and disinfection of water treatment in bathrooms, and dodecyl diaminoethyl glycine, which is called benzalkonium chloride and Tego, which has surface activity in penetration of tiles, walls, etc., which are difficult to penetrate chlorine dioxide. Hydrochloride can be added to maximize efficacy.
The present invention also provides a composition for disinfecting or disinfecting air or hands in which benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride are added in an amount of 0.1 to 0.2%, respectively, in an aqueous solution of 20 to 40 ppm of chlorine dioxide.
The present invention also provides an air or hand comprising treating a composition comprising 20 to 40 ppm chlorine dioxide, 0.1 to 0.2% benzalkonium chloride, and 0.1 to 0.2% dodecyl diaminoethyl glycine hydrochloride It provides a method for sterilizing or disinfecting.
The composition according to the present invention can be prepared for air sterilization, disinfectant spray and hand wash use, by adding benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride, called Tego, which has a surfactant in the sterilization and disinfection power of chlorine dioxide, It can maximize the penetration effect on the skin.
Existing products on the market as a disinfectant and disinfectant for the back of the hand almost do not have the sterilization and disinfection power as an alcohol formulation, by using the composition of the present invention, it is possible to effectively prevent swine flu in advance. This is because the use of chlorine dioxide has been expanded to date, and various applications are possible.
Hereinafter, the present invention will be described in more detail with reference to Examples.
However, these examples are merely exemplary embodiments presented to aid the understanding of the present invention, and the protection scope of the present invention is not limited to these examples.
Example 1 Preparation of Composition 1
An aqueous solution of chlorine dioxide at a concentration of 2,000 ppm was placed in a 1 liter container, and benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride, called Tego, were added thereto so as to have a concentration of 0.15%.
Example 2 Preparation of Composition 2
A 30 ppm concentration of an aqueous solution of chlorine dioxide was placed in a 1 liter container, and benzalkonium chloride and dodecyl diaminoethyl glycine hydrochloride, called Tego, were added thereto so as to have a concentration of 0.15%.
Example 3 Confirmation of Sterilization and Disinfection Effects of Compositions 1 and 2
1 ml of the interference substance and 1 ml of the test strain (E. coli, Pseudomonas aeruginosa, Salmonella, Shigella, Staphylococcus aureus) suspension were added to the test tube, mixed immediately, and left in a 20 ° C constant temperature water bath for 2 minutes. 8 ml of 1 was added and mixed, followed by reaction for 5 minutes in a 20 ° C. constant temperature water bath. 1 ml of this reaction mixture was taken and placed in a test tube containing 8 ml of a neutralizing agent and 1 ml of water, and neutralized in a 20 ° C. constant temperature water bath for 5 minutes. After completion of neutralization, 1 ml of the neutralization reaction solution was added to each of two Petri dishes and cultured by adding TSA medium. The maximum colonies were counted in a Petri dish and the number of viable cells ( N a ) due to the disinfectant action of the test solution was calculated according to the above formula.
As a result, as shown in Table 2 and Figures 1 to 5, the composition of the present invention showed a powerful effect of removing 100% of various bacteria even in a 10-second reaction (Table 2, and Figures 1 to 5). .
Staphylococcus
In addition, the staphylococcus aureus suspension and the composition 2 were operated similarly to the said test method, and the number of live microorganisms by a bactericidal effect was calculated.
As a result, the composition 2 also showed an effect of removing 100% in 10 seconds response to Staphylococcus aureus
As seen above, by using the composition containing chlorine dioxide according to the present invention can be effectively used for sterilization and disinfection of various water, such as bathroom, kitchen, etc. May also be usefully used.
1 is a figure showing the bactericidal efficacy against E. coli of the composition 1 of the present invention.
Figure 2 is a figure showing the bactericidal efficacy against Pseudomonas aeruginosa of Composition 1 of the present invention.
Figure 3 is a figure showing the bactericidal efficacy against Salmonella of Composition 1 of the present invention.
Figure 4 is a figure showing the bactericidal efficacy against Shigella bacteria of Composition 1 of the present invention.
5 is a view showing the bactericidal efficacy against Staphylococcus aureus of the composition 1 of the present invention.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020090115857A KR20110059203A (en) | 2009-11-27 | 2009-11-27 | Composition for disinfection containing chlorine dioxide |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020090115857A KR20110059203A (en) | 2009-11-27 | 2009-11-27 | Composition for disinfection containing chlorine dioxide |
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| Publication Number | Publication Date |
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| KR20110059203A true KR20110059203A (en) | 2011-06-02 |
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| KR1020090115857A KR20110059203A (en) | 2009-11-27 | 2009-11-27 | Composition for disinfection containing chlorine dioxide |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210091869A (en) * | 2020-01-15 | 2021-07-23 | 김경태 | Snow removal agent composition |
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2009
- 2009-11-27 KR KR1020090115857A patent/KR20110059203A/en not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210091869A (en) * | 2020-01-15 | 2021-07-23 | 김경태 | Snow removal agent composition |
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