KR20100009286A

KR20100009286A - Food composition stimulating the smell or the palate for treating addiction through the aversive-typed virtual reality treatment system

Info

Publication number: KR20100009286A
Application number: KR1020080070118A
Authority: KR
Inventors: 이상훈
Original assignee: 이상훈
Priority date: 2008-07-18
Filing date: 2008-07-18
Publication date: 2010-01-27

Abstract

PURPOSE: A food composition stimulating the smell or the palate for treating addiction through an aversive-typed virtual reality treatment system is provided to enable a user to conveniently dose the food composition for the treatment of addiction. CONSTITUTION: Based on the behavior in the specific poisoning of a patient, a virtual environment library stored at a virtual reality library DB is read out. The virtual poisoning environment for the corresponding patient is constructed and outputted. In order to induce the stimulation for the aversion of the addition, a video or audio file stored at a video file DB or audio file DB is read out. After healing the addiction, the material for stimulating the sense of smell or palate is used.

Description

Food composition stimulating the smell or the palate for treating addiction through the aversive-typed virtual reality treatment system

The present invention relates to a method of using a substance that stimulates the sense of smell or taste as a means of aversive stimulation during or after the treatment of addiction through the aversive induction system of the virtual environment, and the olfactory or taste stimulating substance of the aversion induction system in the virtual environment. A food composition for aversive stimulation through a virtual environment aversion inducing system containing as an active ingredient, specifically, to prepare an olfactory or taste stimulating substance in the form of a portable and easy to take food such as jelly, gum, candy, beverages, etc. It is possible.

Addiction is the urge to lose control and repeat one thing or the action of the urge, and medically classify this addiction as an addiction disease. The most common cases of addictive diseases are addictions to alcohol, nicotine, gambling, drugs, etc. Gambling and drug addictions cause serious legal and social problems, and the rapid development of the Internet has led to a rapid increase in youth. Internet addiction and game addiction can not only reduce academic efficiency but also affect youth's values and identity, which can hinder the formation of proper personality. In addition, because obesity caused by refraining from the impulse of food intake is considered as a kind of meal addiction, it can be included in the concept of widespread poisoning disease.

Treatment of addiction disease can be divided into drug treatment and non-drug treatment. In the case of drug treatment, anti- craving agents that reduce the cravings of certain addictions, neuro-stabilizing agents for psychological stability, and symptomatic treatment in the case of certain mental diseases are accompanied. It will be administered for the treatment of mental disorders. Non-drug therapy involves identifying the psychological, mental and social factors involved in causing addiction disorders, and then conducting personal psychotherapy, group education, family therapy, or psychological play. Although a combination of drug and non-drug treatments have improved a number of symptoms of addiction, many patients still have difficulty coping with the cravings associated with specific addictions. .

In the case of alcoholism, for example, estimates of recurrence rates of patients discharged after alcoholism treatment, such as drug and psychotherapy, alcohol alliance, alcohol education and recurrence prevention programs, and family therapy, 50% in one month, Within 6 months, 81.2% recurred (Kang, et al., Jan. 2006, Neuropsychiatric Medicine), and existing alcohol programs alone have limited therapeutic effects, and the development of new treatments has emerged as an urgent challenge. have.

Accordingly, the present inventors have conducted extensive research to solve the above-mentioned problems. As a result, the hate stimulation through the virtual environment and the multi-sensory device according to the present invention can maximize the treatment effect of addiction, and was used for the hate stimulation. The present invention has been completed by confirming that the olfactory or taste stimulating substance can be contained in foods and carried, thereby effectively preventing the recurrence of poisoning.

In the case of conventional drug or non-drug addiction treatment, since there is a high risk of recurrence after treatment, in the present invention, the effect of addiction treatment is enhanced by easily carrying and taking during or after aversive treatment in a virtual environment for a specific poisoning. It is intended to provide a food composition and a method of using the olfactory or taste stimulating substance of the aversive-induced treatment method as an active ingredient in a virtual environment that can prevent recurrence.

The present invention relates to a method of using a substance that stimulates the smell or taste as a means of aversive stimulation during or after the addiction treatment through the aversive induction system in a virtual environment, and the olfactory or taste stimulating substance of the aversion induction system in a virtual environment. The present invention relates to a food composition for aversive stimulation through a virtual environment aversive induction system containing an active ingredient.

During or after the addiction treatment through the aversive induction system of the virtual environment according to the present invention, a substance that stimulates the sense of smell or taste is used as a means of aversive stimulation, and the smell of the aversion induction system in the virtual environment according to the present invention. Or by making the food composition for aversive stimulation through a virtual environment aversion-inducing system containing a taste stimulant as an active ingredient in a portable and easy-to-use food form, When an impulse (craving) occurs by the ingestion of the food composition to effectively respond to the aversive learning effect on the poisoning substance can prevent the recurrence of a particular poisoning.

The present invention relates to a method of using a substance that stimulates the sense of smell or taste as a means of aversive stimulation during or after treatment of addiction through an aversion-inducing system in a virtual environment.

In addition, the present invention relates to a food composition for treating poisoning through a virtual environment hate-inducing system containing an olfactory or taste stimulating substance of the virtual environment hate-inducing system as an active ingredient.

The present invention will be described in more detail as follows.

The hate-inducing system of the virtual environment reproduces the situation related to a particular addiction in a virtual environment to artificially induce cravings (pulses) and then repeats the process of stimulating the hate so that hate learning about specific poisoning substances is performed to treat addictive diseases. It is a process.

The customized virtual environment hate induction system for a specific poisoning patient of the present invention is a virtual reality library DB that stores various types of virtual environment libraries for possible addiction behaviors, and various video files required for a specific addiction treatment process are stored. It is made based on a database consisting of a video file DB and an audio file DB that stores various audio files necessary for a particular addiction treatment process, and the muscle relaxation video file stored in the video file DB or the audio file DB for muscle relaxation. Or (a) outputting an audio file; (B) outputting the virtual environment library stored in the virtual reality library database based on the actual specific addiction behavior of the patient and outputting the virtual addiction environment of the patient after outputting it; And (c) importing and outputting the hate stimulus video file or the audio file stored in the video file DB or the audio file DB.

In the above-described configuration, it is preferable to emit together the aromatic aroma for relaxation of mind and body in the step (a). On the other hand, at least one or more virtual environment libraries are stored in the virtual environment library DB, and in the step (b), the construction of the virtual drinking environment is at least one or more of the virtual reality. A library may be loaded and executed in the virtual environment library DB. In the step (c), the video file or the audio file for inducing hate stimulation is preferably an image or sound of vomiting or death caused by an addiction phenomenon, and furthermore, in step (c), olfactory stimulation associated with vomiting or death. It is preferable to perform the taste stimulation or the tactile stimulation together. The olfactory or taste stimulation of step (c) may be performed again to prevent recurrence in daily life after virtual aversion treatment.

Specific addiction according to the present invention is preferably alcoholism, nicotine addiction, drug addiction, food addiction, in particular alcohol addiction or food addiction is most preferred, but is applicable to all cases of addiction known to those skilled in the art.

As an example of a virtual environment related to a particular addiction, a virtual bar for alcoholism, a specific food for obesity, or a cigarette for nicotine addiction are preferable, but it may cause an addiction patient to associate with or cause cravings. Any environment can be used.

Hate stimulation results in the disgusting physiological phenomena (reactions) that a person originally had, such as vomiting (irritation). By being conditioned response and aversion to toxic substances, it is possible to control intense desire for specific toxic substances gradually through the repetition of this aversive stimulus process.

However, in the midst of treatments that do not undergo virtual environment hate treatment, or during periodic reinforcement training after hate treatment, if the situation related to addiction is encountered again in real life, there is a tendency to use the poisoning material again. For example, if you want to drink in front of a liquor house or you want to smoke when you are stressed, or if you have a strong appetite to eat in front of certain fast foods.

Accordingly, the present invention is a food composition for the treatment of addiction through a virtual environment aversive treatment method containing the olfactory or taste stimulus material of the virtual environment aversion inducing system as an active ingredient, and learned the aversive recognition through the virtual environment aversion treatment The present invention relates to an aversive therapeutic food composition that can be used preliminarily to prevent unexpected urges or to prevent unexpected urges, as well as can be used for taste or olfactory stimulation during the course of aversive treatment.

The substance contained in the food composition for treating addiction through the virtual environment aversive induction system is a material capable of stimulating the taste or smell in the virtual environmental aversion treatment process or after the treatment, the olfactory or taste stimulating substance is vomiting stimulation The substance is preferred. In addition, the form of the food composition is preferably a jelly, gum, candy, drinks, beverages, pills, granules, the form of the food composition can be changed by those skilled in the art according to the preference of the patient to be treated.

It is also possible for the present invention to include a portion of the components of certain poisoning substances as additives. For example, the liquid component remaining after boiling alcoholic alcohol by removing alcohol, and in the case of food poisoning, is caused by a specific poisoning substance by directly mixing some of the spices or contents associated with a particular food with the taste or olfactory irritant It is possible for the impulse to be suppressed by the aversive stimulus contained in the food. In addition, the food is preferred for the treatment of addictive diseases because the food will lose the addiction tendency of the specific poisoning substance itself.

In one embodiment of the present invention, the virtual environment aversive treatment may use the stock solution of Tibet lactic acid bacteria as an aversive stimulus material associated with vomiting. In case of visual or auditory stimulation related to vomiting, it can be stimulated sufficiently through video or video signals related to vomiting. However, in order to stimulate all five senses, the sense of smell or taste is required. It is preferable to use kefir as a therapeutic aid.

Kefir, a stock solution of Tibetan lactic acid bacteria, is a type of fermented milk derived from the Caucasus mountainous region, also known as Tibet mushroom, which is a complex of lactic acid bacteria and yeast, and grows into a grain like jelly. The lactic acid bacteria that make up the granules were mostly lactic acid bacteria, and Lactobacillus, Lactococcus, Leuconostoc, Acetobacter, Streptococcus spp. Kluyveromyces, Torula, Candida and Saccharomyces spp. In addition, these lactic acid bacteria and yeast are surrounded by kefiran, a water-soluble polysaccharide produced during fermentation, to form a grain shape. The physiological activities of caffeine known to date are mainly antimicrobial, intestinal, and excellent immune and anticancer effects (Meydani SN, Ha WK. Immunologic effects of yogurt. Am J Clin Nutr., 71 (4), pp861-72 , 2000). Kefir is a form of pickled milk. At first, the concentration is too high to avoid the invasion of various bacteria, and lactic acid bacteria resistant to comparative salts are naturally taken in from the air. When fermenting kefir, the time of fermentation is sour and sorable to drink, but pH is close to acid, which prevents the influx of bacteria such as decay bacteria living only in a neutral environment, and has a sterilizing effect. In other words, the increased acidity due to fermentation shows a bactericidal effect, so even if the fermentation of kefir for a long time does not become corrupt.

In general, Tibet lactic acid bacteria to drink as a health food is made of fermentation within two days to a week is not sour taste. Tibet lactic acid bacteria of the present invention is preferably filled in a sealed container with Tibet lactic acid bacteria about 2/3 and fermented at room temperature for about a week to a month, it is possible to culture in a general culture method. If the taste of the Tibetan lactic acid bacteria is sufficiently sour and can be used as an olfactory or taste irritant material according to the present invention, Tibetan lactic acid bacteria cultured within a week are also possible.

Tibet lactic acid bacteria stock solution (kefir) is a liquid and the longer the fermented, because the disgusting smell similar to the vomiting has a disadvantage that is usually difficult to carry.

Therefore, in the present invention, it is preferable to prepare the Tibetan lactic acid bacteria stock solution with gelatin to make a jelly form, or to prepare candy, gum, drink form, pill form, and granule form. The formulations may be prepared including various additives by conventional methods known to those skilled in the art, and the form of the formulation may be modified in a manner changeable to those skilled in the art. In the food composition of the present invention, the Tibet lactic acid bacteria is preferably contained in 30 to 80% by weight. If it contains less than 30%, it is difficult to fully expect the olfactory and taste stimulating effect according to the present invention, and if it is more than 80%, it is difficult to maintain the food form, such as jelly. The composition ratio of the Tibetan lactic acid bacteria can be changed as long as it does not degrade the olfactory or taste stimulating effect of the Tibetan lactic acid bacteria, it is also possible to intake only 100% Tibet lactic acid bacteria.

Carriers, excipients and diluents that may be included in the compositions of the present invention include lactose, dextrose, sucrose, sorbitol, mannitol, xylitol, erythritol, maltitol, starch, acacia rubber, alginate, gelatin, calcium phosphate, calcium silicate, Cellulose, methyl cellulose, microcrystalline cellulose, polyvinyl pyrrolidone, water, methylhydroxybenzoate, propylhydroxybenzoate, talc, magnesium stearate and mineral oil.

Compositions comprising the compounds according to the invention can be used in the form of oral preparations, such as powders, granules, tablets, capsules, suspensions, emulsions, syrups, aerosols, etc., respectively, according to conventional methods. Specifically, when formulated, it may be prepared using diluents or excipients such as fillers, extenders, binders, wetting agents, disintegrating agents, surfactants, etc. which are commonly used. Solid preparations for oral administration include tablets, pills, powders, granules, capsules, and the like, and such solid preparations may contain at least one excipient such as starch, calcium carbonate, sucrose, or the like. ), Lactose, gelatin and the like can be mixed. In addition to simple excipients, lubricants such as magnesium stearate, talc can also be used. Liquid preparations for oral use include suspensions, solvents, emulsions, and syrups, and include various excipients such as wetting agents, sweeteners, fragrances, and preservatives, in addition to commonly used simple diluents such as water and liquid paraffin. Can be.

Since the food composition of the present invention has little toxicity and side effects, it can be used with confidence even for long-term use for the purpose of prevention.

In addition, the composition containing the taste or smell stimulant of the present invention can be used in a variety of food and beverages.

Foods to which the composition of the present invention may be added include various foods, for example, candy, chocolate, beverages, gums, teas, vitamin complexes, health functional foods, and the like, which are powders, granules, tablets, capsules, or beverages. Available in form. At this time, the amount of the irritant in the food or beverage, in general, in the case of the health functional food composition of the present invention can be added to 30-100% by weight, preferably 30 to 80% by weight of the health functional beverage composition, In the case of 100 ml may be added in a ratio of 30 to 100 ml, preferably 30 to 80 ml. The food composition of the present invention does not have any particular limitations on the liquid component except that it contains a taste or olfactory irritant, and may contain various flavors or natural carbohydrates as additional ingredients, such as ordinary drinks. Examples of the above-mentioned natural carbohydrates include monosaccharides such as glucose, fructose and the like; Disaccharides such as maltose, sucrose and the like; Polysaccharides such as conventional sugars such as dextrin, cyclodextrin and the like and sugar alcohols such as xylitol, sorbitol, erythritol and the like. The proportion of natural carbohydrates includes conventional proportions known in the art. As other flavors, natural flavors (tauumatin, stevia extract: for example, rebaudioside A, glycyrrhizin, etc.) and synthetic flavors (saccharin, aspartame, etc.) can be advantageously used. In addition, the composition of the present invention is a variety of nutrients, vitamins, minerals (electrolytes), flavors such as synthetic flavors and natural flavors, colorants and fillers (such as cheese, chocolate), pectic acid and salts thereof, alginic acid and salts thereof , Organic acids, protective colloid thickeners, pH adjusters, stabilizers, preservatives, glycerin, alcohols, carbonation agents used in carbonated drinks, and the like. In addition, the compositions of the present invention may contain flesh for the production of natural fruit juices and fruit juice beverages and vegetable beverages.

According to an embodiment of the present invention, a customized virtual environment aversion treatment method for alcoholism patients is a virtual reality library DB that stores various types of virtual reality library for drinking behavior possible in reality, various kinds of alcoholism treatment process It is made on the basis of a database consisting of a video file DB that stores the video file and an audio file DB that stores various audio files necessary for the alcoholism treatment process, stored in the video file DB or the audio file DB for muscle relaxation (A) outputting the prescribed muscle relaxation video file or audio file; (B) a step of importing various virtual environment libraries stored in the virtual reality library DB based on a patient's actual drinking behavior and constructing the virtual drinking environment of the patient and outputting the virtual drinking environment; And (c) importing and outputting a video file or audio file for aversive stimulation stored in a file DB or the audio file DB.

In the above-described configuration, it is preferable to emit together the aromatic aroma for relaxation of mind and body in the step (a). Meanwhile, at least one virtual reality library is stored in the virtual reality library DB by alcohol type, snack type, place type, time type, or person type, and the virtual drinking environment construction in the step (b) is the type. At least one or more of the virtual reality library in some or all of the may be performed by loading from the virtual environment library DB. In the step (c), the video file or the audio file for inducing aversive stimulation is preferably an image or sound for vomiting or death caused by drinking, and furthermore, in step (c), olfactory stimulation associated with vomiting or death, It is preferable to perform taste stimulation or tactile stimulation together. The olfactory or taste stimulation of step (c) may be performed again to prevent recurrence in daily life after virtual aversion treatment. The olfactory or taste irritant material performed in the virtual aversive treatment step of the present invention is preferably easy to take, easy to carry jelly, chewing gum, candy, beverages, drinks, pills, granules, the form of the food composition to those skilled in the art It is possible to change depending on whether or not.

In alcoholic patients, there are many factors affecting recurrence after discharge, so it is practically difficult to cure a single drug or treatment. However, a combination of effective treatments, combined with the appropriate combination, can significantly reduce recurrence rates. Most alcoholic patients have not received the most appropriate training in actual drinking situations even though they have received proper medication and psychotherapy, so when exposed to actual drinking conditions, it is difficult to overcome the drinking urge that occurs, leading to relapse. There are many. Therefore, when the virtual environment hate treatment and the food composition according to the present invention are commonly used in everyday life together with the existing drugs and psychotherapy, the ability to cope with alcohol in actual drinking situations is increased, thereby increasing the success rate of existing treatments for a long time. This is a great help in maintaining a short note.

EXAMPLE

The following preparation examples are intended to specifically explain the contents of the present invention, whereby the scope of the present invention is never limited and can be interpreted.

Production Example 1. Preparation of Beverages

Purified water was added to 700 ml of Tibetan lactic acid bacteria, 100 mg of citric acid, 100 g of oligosaccharide, 2 g of plum concentrate, and 1 g of taurine to make the whole to 1000 ml. After mixing the above components according to a conventional drink preparation method, and stirred at 85 ° C for 1 hour, heated, and then put the resulting solution in a sterile container sealed sterilization and refrigerated.

Production Example 2. Preparation of Jelly

Sugar is added so that the ratio of Tibetan lactic acid sugar is 60:40, 2% of pectin and 0.3% citric acid of the total weight are mixed and heated and concentrated while stirring at a speed of 100 rpm at a temperature of 100 ° C., 3% of honey, After adding 2% of glucose and 0.5% of vitamin C, the solution was poured into a mold prepared in advance, homogenized, and cooled to 3 ° C. in a large refrigerator to obtain a jelly product.

Example 1. Alcoholism after taking jelly for the treatment of addiction through the treatment of environmental aversion Recurrence rate

Ten patients with alcoholism were treated with virtual environment aversive treatment. First, the patient's muscles were relaxed by releasing relaxing natural scenery, quiet classical music, and aroma, and then exposed to a virtual reality environment including alcohol, snacks, and pubs as shown in FIG. Then, to induce aversive stimulation, while showing the image of the vomiting, death caused by drinking as shown in Figure 1 (b) with a sound, to drink the beverage according to Preparation Example 1.

The hospital was treated 15 times for a month and a half after being admitted to the virtual aversion treatment process, and afterwards, he was discharged once every 15 days, and received reinforcement treatment in the same manner as hospitalization treatment. After each instruction to take the jelly according to Preparation Example 2, it was confirmed whether drinking after one month and six months. As a result, 3 out of 10 alcoholic patients recurred after 1 month. The recurrence rate was 30% after 1 month, and 5% after 6 months with 50%. This is a remarkable decrease in the relapse rate compared to the relapse rate of conventional drug treatment and psychotherapy (monthly: 50%, 6 months: 81.2%). In addition, most of the patients who participated in the treatment showed that the psychological confidence that they could overcome the drinking urge even when exposed to the actual drinking situation through the use of jelly increased.

1 is an example of (a) a virtual reality environment and (b) an aversion stimulus in accordance with the present invention.

Claims

A virtual reality library DB that stores various types of virtual environment libraries for possible addiction behavior in reality, a video file DB that stores various video files for a specific addiction treatment process, and various audio files for a specific addiction treatment process. (A) outputting a muscle relaxation video file or an audio file stored in the video file DB or the audio file DB to be made on the basis of a database composed of an audio file DB;

(B) importing various virtual environment libraries stored in the virtual reality library DB based on the actual specific addiction behavior of the patient and constructing and outputting the virtual addiction environment of the patient; And

(C) importing and outputting a video file or audio file for aversive stimulation stored in the video file DB or the audio file DB to induce aversive stimulus for poisoning;

A method of using a substance that stimulates the sense of smell or taste as a means of aversive stimulation, either during step (c) or after treatment of addiction through the systems of (a) to (c).

The method of claim 1, wherein the olfactory or taste stimulating substance is a substance that stimulates vomiting.

The method of claim 2, wherein the substance that stimulates vomiting is Tibetan lactic acid bacteria.

The method of claim 1, wherein the addiction is alcoholism, nicotine addiction or food addiction (obesity).

A food composition for aversive stimulation of a virtual environment aversion-inducing system containing a substance stimulating vomiting according to claim 2 as an active ingredient.

The food composition of claim 5, wherein the substance that stimulates vomiting is Tibetan lactic acid bacteria.

The food composition of claim 6, comprising 30 to 80% by weight of Tibet lactic acid bacteria.

The food composition according to any one of claims 5 to 7, wherein the food composition may be prepared in any one form selected from the group consisting of jelly, gum, candy, beverage, and granules.