KR20080110349A - Disinfectant having ozone - Google Patents

Disinfectant having ozone Download PDF

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Publication number
KR20080110349A
KR20080110349A KR1020070059002A KR20070059002A KR20080110349A KR 20080110349 A KR20080110349 A KR 20080110349A KR 1020070059002 A KR1020070059002 A KR 1020070059002A KR 20070059002 A KR20070059002 A KR 20070059002A KR 20080110349 A KR20080110349 A KR 20080110349A
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KR
South Korea
Prior art keywords
ozone
liquid paraffin
disinfectant
petrolatum
skin
Prior art date
Application number
KR1020070059002A
Other languages
Korean (ko)
Inventor
유화정
황현태
Original Assignee
유화정
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 유화정 filed Critical 유화정
Priority to KR1020070059002A priority Critical patent/KR20080110349A/en
Priority to PCT/KR2007/002945 priority patent/WO2007145493A1/en
Priority to JP2008553187A priority patent/JP4873755B2/en
Priority to EP07746979A priority patent/EP2037969A1/en
Priority to US12/336,291 priority patent/US20090117055A1/en
Publication of KR20080110349A publication Critical patent/KR20080110349A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22Peroxides; Oxygen; Ozone

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to an ozone-containing disinfectant, and more specifically, to remove bacteria or fungi of the skin and to prevent bacterial invasion from the outside, so that ozone is contained therein by injecting ozone into petroleum jelly or liquid paraffin. And it is applied to the skin to sterilize bacteria sterilizing bacteria, characterized in that the technical gist, so when applied to the surface or wound of the skin bacteria or molds are sterilized by ozone contained inside Since a film is formed in the membrane, it is possible to prevent bacterial invasion from the outside.

Description

Disinfectant having ozone

1: Pictures showing the test of the bactericidal power of S. mutans bacteria of the liquid paraffin containing general liquid paraffin and ozone

Figure 2: Pictures showing the test for the bactericidal activity of S. mutans bacteria of petrolatum containing petrolatum and ozone

Figure 3: Pictures of the test for the bactericidal power of S. mutans bacteria of olive oil containing normal olive oil and ozone

Figure 4: Photograph testing the sterilizing power of ozone-containing liquid paraffin over time exposed to ozone

Fig. 5: Pictures of the bactericidal power against ozone-containing Vaseline T.mentagrophytes

Figure 6: Pictures of the test of the bactericidal power against T.mentagrophytes bacteria of PM

Figure 7: Photograph of the bactericidal power against Namisol T.mentagrophytes

The present invention relates to a disinfectant containing ozone, and more particularly, to inject ozone into petrolatum or liquid paraffin to contain ozone therein.

If the human body is injured, the bacteria invade through the wound, resulting in more damage. In order to prevent the invasion of these bacteria, disinfectants such as alcohol or hydrogen peroxide solution or antibiotics are used.

The disinfectant is made of a liquid and requires a separate cotton and has a bactericidal effect during application to the skin, but will soon evaporate or change to disinfect. Therefore, the circumference of the wound should be wrapped with a gauze or band-aid to prevent the invasion of bacteria.

In addition, when sterilization using penicillin or other ointments made of antibiotics, the sterilization is excellent, but if the bacteria are resistant to the antibiotic, the sterilization is not performed. There is this.

Recently, sterilization methods using ozone instead of conventional disinfectants or antibiotics have been studied. The ozone is a substance composed of oxygen atoms, but excellent in sterilization, but has a short half-life, which is difficult to preserve for a long time, and has a high toxicity and is harmful to the human body at high concentrations. To solve this problem, a method of dissolving and preserving ozone at low concentrations such as olive oil or sunflower seed oil has been developed. Such ozonized oil is used for acne or atopic dermatitis.

However, when the ozone is added to the vegetable oil to make the ozonated oil as described above, there is a concern that the vegetable oil may be deteriorated when stored for a long time, and the sterilizing power is also lowered.

The present invention has been made to solve the above problems is to provide a disinfectant containing ozone that is harmless to the human body, shows high sterilizing power when applied to the skin and does not occur resistance.

Another object of the present invention is to provide a disinfectant containing ozone that is easily produced in an ointment form to form a film when applied to the skin to block bacterial invasion from the outside.

Another object of the present invention is to provide a disinfectant containing ozone that does not cause deterioration even during long-term storage and that can maintain its sterilizing power continuously.

The present invention is a technical gist of ozone-containing disinfectant, characterized in that by injecting ozone into petrolatum or liquid paraffin to contain ozone inside and to apply it to the skin to sterilize bacteria.

According to a preferred embodiment, the fluid paraffin is characterized in that the ground jelly is mixed to form an artificial petrolatum form.

According to a preferred embodiment the concentration of ozone is characterized in that less than 100PPM.

The present invention is to provide a disinfectant that is harmless to the human body and shows high sterilizing power when applied to the skin and does not generate resistance. To this end, in the present invention, ozone is added to the inside of the liquid paraffin or petroleum jelly to be contained. This is because ozone is added to liquid paraffin or petroleum jelly, which is harmless to the human body, so that it can be sterilized by ozone when applied to the skin, and thus there is no resistance generated when using antibiotics. In particular, the use of liquid paraffin or petrolatum, there is no fear of deterioration and can be stored for a long time sterilizing ozone.

Hereinafter, a disinfectant containing ozone according to an embodiment of the present invention will be described in detail.

The ozone-containing disinfectant of the present invention is such that ozone is contained in petrolatum or liquid paraffin. In the embodiment of the present invention is to use the 75F of the floating paraffin on the market as the floating paraffin. The 75F is a liquid paraffin having a specific gravity of about 0.832. However, it is not limited to 75F as mentioned above. The liquid paraffin may be selected and used to have a suitable viscosity depending on the intended use.

After placing the liquid paraffin in the airtight container as described above, a tube to which ozone is supplied is placed, and then ozone passes through the liquid paraffin. At this time, it is also considered to stir the liquid paraffin using a stirring device so that the liquid paraffin and ozone can be mixed better. As described above, when ozone is continuously added to the liquid paraffin for a predetermined time and ozone is sufficiently contained therein, the ozone gas located at the upper side of the container is removed, and then the liquid paraffin is taken out and stored.

Here, in the embodiment of the present invention, ozone may cause harm to the human body when the concentration is high, so that the concentration is kept below 100PPM. However, the concentration of ozone may be 100 PPM or more. In general, in the case of ozone in the atmosphere, the ozone caution is issued when it is 0.12PPM or more. However, in the present invention, ozone is contained in the floating paraffin, so there is almost no amount flowing out into the atmosphere. The amount of ozone that is actually in contact with the human body is extremely small, so even if the concentration is high, it is judged to be harmless to the human body.

In another embodiment of the present invention, ozone is added to petrolatum instead of liquid paraffin. The petrolatum is placed in a sealed container and stirred while supplying ozone therein so that the petrolatum contains ozone.

Also, instead of petrolatum, artificial petrolatum made by mixing zebra with liquid paraffin may be used.

Hereinafter will be described the action of the disinfectant containing ozone according to an embodiment of the present invention.

First, the disinfectant which contains ozone in liquid paraffin and petrolatum is compared with the sterilizing power of ozone in conventional olive oil.

Experiments were conducted using ozone-containing liquid paraffin and ozonated olive oil in commercially available olive oil.

In the experiment, one S. Mutans colony was inoculated in 10 ml of BHI broth, shaken and cultured, and the culture solution was uniformly coated on a BHI agar plate, and the liquid paraffin, petrolatum, and olive oil containing ozone were applied thereon. At this time, in order to compare the sterilizing power, the liquid paraffin, petrolatum, and olive oil which do not contain ozone are applied together. Then observe after incubation in an incubator at 37 degrees.

Figure 1 is a comparison of the normal paraffin and the liquid paraffin containing ozone can be seen that there is no colony in the case of the liquid paraffin on the right is completely sterilized.

Figure 2 is a comparison of petrolatum containing petrolatum and ozone, it can be seen that there is a few colonies in the case of petrolatum containing ozone on the right.

Figure 3 is a comparison between olive oil containing the normal olive oil and ozone. There are many colonies present in the olive oil containing ozone on the right. Therefore, it can be seen that olive oil containing ozone has a slight germicidal power but is less sterilized than liquid paraffin or petrolatum.

Next, the difference in the sterilizing power according to the time exposed to ozone in the ozone-containing liquid paraffin of the present invention will be described.

Experiments for this purpose were supplied to the liquid paraffin for 10 minutes, 1 hour, 4 hours, 10 hours, 24 hours, respectively, mixed with the T.mentagrophytes strain causing athlete's foot, and left for 1 minute, and then strained using a centrifuge After separation, the cells were incubated for 3 days in an incubator at 25 ° C and observed.

Figure 4 shows the results of the above experiment was exposed to ozone for 10 minutes, 1 hour, 2 hours, 4 hours, 10 hours, 24 hours from the upper left, according to this, in the case of the disinfectant containing ozone of the present invention has a long time It can be seen that the sterilization is improved when exposed.

Next, the athlete's foot fungus compared to the athlete's foot commercially available on the market will be tested.

5, 6 and 7 show the results of comparing the petroleum-containing petroleum jelly (PM and namisol) commercially available with ozone of the present invention. Fig. 5 shows the result after applying petroleum jelly containing the present invention, Fig. 6 is a coating of PM, and Fig. 7 is a coating of namisol. According to the figure, the existing drugs used in athlete's foot on the fungus were found to have superior effects than the ozonated petrolatum of the present invention.

However, the ozonated petrolatum of the present invention is not resistant, and it can be expected that the moisturizing effect of petrolatum has little irritation to the skin, and thus the effect in clinical is expected to be higher than expected.

As described above, it can be seen that the ozone-containing disinfectant of the present invention has excellent sterilizing power compared to ozonated olive oil. In addition, unlike olive oil, the liquid paraffin or petrolatum has no deterioration, and since ozone contained in the interior is hardly leaked to the outside, it has sterilizing power even when stored for a long time.

Therefore, the ozone-containing disinfectant may be used in the form of a liquid or ointment to disinfect wounds or prevent secondary infections and to treat acne or athlete's foot.

As described above, according to the ozone-containing disinfectant of the present invention, ozone is contained in liquid paraffin or petroleum jelly, which is harmless to the human body, to give bactericidal power, and is applied to the skin by applying it to the skin to apply disinfection to the wound. Covering the site to prevent invasion of external bacteria has the effect of preventing secondary infection.

In addition, it is less resistant and has a moisturizing effect when applied to the skin, so it is safe for long-term use.

Claims (3)

An ozone-containing disinfectant, characterized by injecting ozone into petroleum jelly or liquid paraffin to allow ozone to be contained therein and to apply it to the skin to sterilize bacteria. The method of claim 1, The liquid paraffin is ozone-containing disinfectant, characterized in that the mixture is made of petroleum jelly. The method of claim 1, Disinfectant containing ozone, characterized in that the concentration of ozone is less than 100PPM.
KR1020070059002A 2006-06-16 2007-06-15 Disinfectant having ozone KR20080110349A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
KR1020070059002A KR20080110349A (en) 2007-06-15 2007-06-15 Disinfectant having ozone
PCT/KR2007/002945 WO2007145493A1 (en) 2006-06-16 2007-06-18 Disinfectant having ozone
JP2008553187A JP4873755B2 (en) 2006-06-16 2007-06-18 Disinfectant containing ozone
EP07746979A EP2037969A1 (en) 2006-06-16 2007-06-18 Disinfectant having ozone
US12/336,291 US20090117055A1 (en) 2006-06-16 2008-12-16 Disinfectant having ozone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020070059002A KR20080110349A (en) 2007-06-15 2007-06-15 Disinfectant having ozone

Publications (1)

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KR20080110349A true KR20080110349A (en) 2008-12-18

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230079544A (en) 2021-11-29 2023-06-07 김환욱 Method for producing ozone-containing luminol salt

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230079544A (en) 2021-11-29 2023-06-07 김환욱 Method for producing ozone-containing luminol salt

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Effective date: 20090227