KR20080074623A - Apparatus for measuring blood pressure and method thereof - Google Patents

Abstract

An apparatus and a method for measuring a blood pressure are provided to improve the accuracy of a diastole blood pressure by calculating a blood pressure value based on physical information of a person to be measured, environmental information, and a systolic blood pressure value at a contraction time. A method for measuring a blood pressure includes the steps of: calculating a pulse wave transmission time(S30) based on a pulse wave and the electrocardiogram which is measured from a person to be measured(S10), and calculating a systolic blood pressure value based on the calculated pulse wave transmission time(S40); and calculating a diastole blood pressure value based on the systolic blood pressure value, the calculated pulse wave transmission time, analysis information of the pulse wave, physical information of a person to be measured, and the measured environmental information in the electrocardiogram and pulse wave measurement(S50).

Description

Blood pressure measuring device and its method {APPARATUS FOR MEASURING BLOOD PRESSURE AND METHOD THEREOF}

1 is a block diagram showing a blood pressure measuring apparatus for measuring the diastolic blood pressure value using the systolic blood pressure value according to an embodiment of the present invention.

2 is a flowchart illustrating a blood pressure measuring method for measuring a diastolic blood pressure value using a systolic blood pressure value according to an embodiment of the present invention.

3 is a waveform diagram for obtaining a pulse wave propagation time according to an embodiment of the present invention.

4 is a waveform diagram for obtaining pulse wave analysis information according to an embodiment of the present invention.

5A and 5B are analytical diagrams showing R-sq (adj) values of diastolic blood pressure and R-sq (adj) values of diastolic blood pressure according to the prior art according to an embodiment of the present invention.

*** Explanation of symbols for main parts of drawing ***

10: sensor unit 20: information input unit

30: control unit 40: output unit

50: storage

The present invention relates to a blood pressure measuring apparatus and a method thereof, and more particularly, to a blood pressure measuring apparatus and method for improving the accuracy of the diastolic blood pressure value by using the systolic blood pressure value during blood pressure measurement.

As the interest in health increases, medical service visits the hospital only when sick and breaks the passive form of receiving prescriptions from doctors.The subject purchases a separate medical device that he / she needs and uses the purchased medical device. Thus, the blood pressure, heart rate, electrocardiogram, pulse rate, respiratory rate, body fat, etc. of the subject can be examined at the place where the subject is desired. The medical signal is transmitted to a medical center through a wired or wireless communication medium such as a mobile phone, a personal digital assistant (PDA), a personal computer (PC), and the like, and receives a consultation and prescription from a specialist based on the transmitted biosignal. On the basis of the prescription, the form of the medical service is being changed to the concept of an active form in which the subject measures according to the situation and prevents a greater illness in advance.

Accordingly, according to the change of the medical service form, the subject can measure his or her own health state by using various products such as a pulse watch in the form of a wrist watch, an oxygen saturation meter, a portable ECG, and the like.

Blood pressure refers to the pressure applied to the blood vessel wall when blood flows through the blood vessel.

In addition, the blood pressure is an important physiological index including a lot of information about cardiac output, blood vessel elasticity, physiological change of the subject.

In addition, the blood pressure is systolic and diastolic (Systolic), which is the highest and lowest blood pressure according to the contraction or relaxation of the heart.

Blood pressure measurement can be divided into invasive and non-invasive methods.

The invasive method is to insert a catheter into a blood vessel to continuously and accurately measure blood pressure. However, such invasive methods can lead to problems with the risk of infection and side effects.

The non-invasive method is mainly a method for measuring blood pressure by detecting the sound or vibration of the pulse while pressing and depressurizing using a cuff, the non-invasive method is limited to continuously measuring the blood pressure. Among other non-invasive methods, a representative method for measuring blood pressure without using a cuff is pulse transit time (PTT) from electrocardiogram (ECG) and photo plethysmogram (PPG). To obtain the blood pressure using the pulse wave delivery time.

Both invasive methods and non-invasive methods are methods for physically detecting the amount of blood vessel expansion or relaxation to obtain blood pressure values.

In the non-invasive method, an indirect measurement method causes some error factor. In particular, in the case of the optical measurement method, the accuracy of the measurement is affected by the causes such as skin thickness, skin components, and the degree of contact of the sensor. In addition, in principle, the diastolic blood pressure may be less accurate than the systolic blood pressure.

An object of the present invention is to measure the electrocardiogram and pulse wave of the subject, to obtain the pulse wave delivery time based on the measured electrocardiogram and pulse wave, to obtain the systolic blood pressure value based on the obtained pulse wave delivery time, By obtaining a diastolic blood pressure value based on the obtained pulse wave propagation time, the measured pulse wave analysis information, the body characteristic information of the subject input by the subject and the environmental information measured at the electrocardiogram and pulse wave measurement, The present invention provides a blood pressure measuring apparatus and a method capable of providing a diastolic blood pressure with high reliability to a subject.

Another object of the present invention is to measure the electrocardiogram and pulse wave of the subject, to obtain the pulse wave delivery time based on the measured ECG and pulse wave, to obtain the systolic blood pressure value based on the obtained pulse wave delivery time, The diastolic blood pressure value is calculated on the basis of the blood pressure value, the obtained pulse wave propagation time, the measured pulse wave analysis information, the physical characteristic information of the subject measured by the subject, and the environmental information measured when measuring the electrocardiogram and pulse wave. Thus, the present invention provides a general regression formula applicable to blood pressure measurement subjects.

Blood pressure measuring apparatus according to the present invention for achieving the above objects, the sensor unit for measuring the electrocardiogram and pulse wave of the subject; Obtaining the pulse wave delivery time based on the measured electrocardiogram and pulse wave, obtaining the systolic blood pressure value based on the obtained pulse wave delivery time, the obtained systolic blood pressure value, the obtained pulse wave delivery time, the analysis information of the pulse wave, the subject And a controller for applying a regression equation to obtain a diastolic blood pressure value based on the body characteristic information of the subject and the environmental information measured at the time of measuring the electrocardiogram and pulse wave.

In addition, the blood pressure measuring method according to the present invention for achieving the above object, the pulse wave delivery time based on the electrocardiogram and pulse wave measured from the subject to obtain a systolic blood pressure value based on the obtained pulse wave delivery time; Applied to the regression equation based on the obtained systolic blood pressure value, the obtained pulse wave propagation time, analysis information of the pulse wave, body characteristic information of the subject input by the subject, and environmental information measured at the electrocardiogram and pulse wave measurement To obtain the diastolic blood pressure value.

Hereinafter, a preferred embodiment of the blood pressure measuring apparatus and method for improving the accuracy of the diastolic blood pressure value by allowing the diastolic blood pressure value to be obtained using the systolic blood pressure value at the time of blood pressure measurement will be described with reference to FIGS. 1 to 5. It will be described in detail.

1 is a block diagram showing a blood pressure measuring device for measuring the diastolic blood pressure value using the systolic blood pressure value according to an embodiment of the present invention, as shown in the blood pressure measuring device, the electrocardiogram or pulse wave of the subject The sensor unit 10 for measuring at least one of the above, the information input unit 20 for receiving the physical characteristic information of the subject and the pulse wave transmission time is calculated based on the measured electrocardiogram and pulse wave, The systolic blood pressure value is obtained based on the moon time, and based on the obtained systolic blood pressure value and pulse wave delivery time, the analysis information of the pulse wave, the input body characteristic information of the subject, and the environmental information measured at the electrocardiogram or pulse wave measurement. Outputting at least one of a control unit 30 for obtaining a diastolic blood pressure value and a systolic blood pressure value or a diastolic blood pressure value obtained by the control unit 30. It consists ryeokbu 40 and a storage unit 50 for storing the systolic pressure value, diastolic or at least one of blood pressure value obtained in the control section 30.

The sensor unit 10 includes an electrode for measuring the electrocardiogram of the subject and a pressure sensor for measuring the pulse wave of the subject.

In addition, the sensor unit 10 is configured to measure at least one or more of the environmental information of the ambient temperature, humidity, air pressure of the subject at the time of measuring the electrocardiogram or pulse wave of the subject.

The information input unit 20 is configured to receive at least one or more body characteristic information of the height, weight, age, and gender of the subject.

The controller 30 is configured to obtain a pulse transit time (PTT) that varies according to the pressure of the artery by using the electrocardiogram and pulse wave of the subject measured by the sensor unit 10.

In addition, the controller 30 obtains a systolic blood pressure value based on the obtained pulse wave delivery time, and the systolic blood pressure value is inversely proportional to the square of the pulse wave delivery time.

In addition, the control unit 30, the obtained systolic blood pressure value, pulse wave transmission time, analysis information of the pulse wave, body characteristic information of the subject input through the information input unit 20 and the electrocardiogram or pulse wave measurement Time is calculated by applying the measured environmental information to the regression equation.

The output unit 40 provides the systolic blood pressure value and the diastolic blood pressure value obtained by the controller 30 to the subject using a wired or wireless medium such as a mobile phone, a personal digital assistant, a personal computer, an e-mail, or the like of the subject. Is done.

The storage unit 50, the systolic blood pressure value and diastolic blood pressure value obtained by the control unit 30, the measured electrocardiogram and pulse wave, the obtained pulse wave transmission time, the input of the subject through the information input unit 20 And at least one of body characteristic information and the measured environmental information.

The blood pressure measuring device may increase the accuracy of the diastolic blood pressure value by configuring the diastolic blood pressure value using the systolic blood pressure value during blood pressure measurement.

In addition, the blood pressure measuring device measures the electrocardiogram and pulse wave from the subject, obtains the pulse wave delivery time based on the measured electrocardiogram and pulse wave, obtains the systolic blood pressure value based on the obtained pulse wave transfer time, Diastolic blood pressure based on systolic blood pressure value, the obtained pulse wave propagation time, analysis information of the pulse wave, body characteristic information of the subject input by the subject, electrocardiogram of the subject to be measured and surrounding environment information measured at the pulse wave measurement By configuring to obtain a value, it is to provide a generalized regression equation applicable to the subjects in measuring blood pressure.

Hereinafter, a blood pressure measuring method for obtaining a diastolic blood pressure value using the systolic blood pressure value according to the present invention will be described in detail with reference to FIGS. 1 to 4.

2 is a flowchart illustrating a blood pressure measuring method for measuring a diastolic blood pressure value using a systolic blood pressure value according to an embodiment of the present invention.

First, the electrocardiogram and pulse wave of the subject are measured using the sensor unit 10.

In addition, when measuring the electrocardiogram and pulse wave of the subject, information about the surrounding environment of the subject is measured at least one of temperature, humidity, and air pressure (S10).

Thereafter, the body characteristic information of the subject is received through the information input unit 20 and stored in the storage unit 50. The physical characteristic information of the subject includes at least one or more of height, weight, age, and gender of the subject. In addition, the body mass index (BMI) is obtained by using the measured height and weight of the subject (S20).

Then, the pulse wave propagation time is obtained using the measured electrocardiogram and pulse wave. The pulse wave propagation time represents a time difference between the time at which the peak value of the R-wave of the electrocardiogram is shown and the time at which the peak value of the pulse wave is shown, as shown in FIG. 3. (S30).

Then, the systolic blood pressure value is obtained based on the obtained pulse wave delivery time. The systolic blood pressure value has a correlation inversely proportional to the square of the pulse wave propagation time. Therefore, the systolic blood pressure value can be obtained by obtaining the pulse wave delivery time (S40).

Thereafter, the diastolic blood pressure value is obtained based on the obtained systolic blood pressure value, the obtained pulse wave propagation time, analysis information of the pulse wave, and physical characteristic information of the subject input by the subject.

In addition, the analysis information of the pulse wave, as shown in Figure 4, obtains the second derivative waveform of the measured pulse wave, of which at least one or more of each peak value or vascular aging degree of the second derivative waveform of the pulse wave Include. That is, the analysis information of the pulse wave includes the peak values a, b, c, d, or the combination of the peak values with each other by arithmetic operation in a waveform obtained by dividing the pulse wave in the second derivative. . That is, for example, values such as a + b, a + c, b + d, b / a, d / c, and (a + b) / c may be used as analysis information of the pulse wave. In addition, the pulse wave analysis information may obtain a pulse rate by analyzing a waveform obtained by first-ordering a pulse wave, and may use the pulse rate as the pulse wave analysis information. Further, the vascular aging degree is obtained by combining the respective peak values when the peak values are sequentially a, b, c, and d in the waveform of the second derivative of the pulse wave, and are expressed by Equation (1). In addition, the vascular aging degree, the higher the value indicates that the vascular aging degree is good. The degree of aging of blood vessels representing the state of blood vessels, when blood clots accumulate in the blood vessel wall, the passage of blood flow in the blood vessels is relatively reduced, thereby increasing resistance, which is a factor that may affect blood pressure.

The diastolic blood pressure value is obtained by combining factors including the systolic blood pressure value, pulse wave propagation time, pulse wave analysis information, body feature information, and environmental information, and is expressed by Equation 2.

Here, C1 to C6 are constants obtained through regression analysis, and additional factors may be used in addition to the factors described for obtaining the diastolic blood pressure (S50).

Thereafter, at least one or more of the obtained systolic blood pressure value or diastolic blood pressure value is provided to the subject using the output unit 40 or stored in the storage unit 50 (S60).

Hereinafter, a comparison result between the R-sq (adj) value of the diastolic blood pressure according to the prior art and the R-sq (adj) value of the diastolic blood pressure using the systolic blood pressure value according to the present invention will be described in detail with reference to FIG. 5. .

5A and 5B are analytical diagrams showing R-sq (adj) values of diastolic blood pressure according to the prior art and the embodiment of the present invention, respectively. As shown in FIG. 5A, R of the diastolic blood pressure according to the prior art is shown. The -sq (adj) value represents 61.0%.

In contrast, the R-sq (adj) value of the diastolic blood pressure according to the exemplary embodiment of the present invention shown in FIG. 5B represents 72.4%, thereby obtaining a diastolic blood pressure value having higher accuracy than the prior art.

The analysis diagram is obtained by using the regression analysis of Minitab Software, which is a regression calculation program stored in the storage unit 50 in advance in the control unit 40.

Here, the R-sq (adj) value is a value representing the explanatory power of the regression equation, and the higher the value, the higher the reliability.

As described in detail above, the blood pressure measuring apparatus and method according to an embodiment of the present invention, using the measured electrocardiogram and pulse wave to obtain the pulse wave transmission time and pulse wave analysis information, the obtained pulse wave transmission time, pulse wave analysis information, By applying the information on the physical characteristics of the subject, the environmental information and the systolic blood pressure value input by the subject to a regression equation to calculate the diastolic blood pressure value, it is possible to increase the accuracy of the diastolic blood pressure value when measuring the blood pressure There is.

In addition, the blood pressure measuring apparatus and method according to an embodiment of the present invention, using the measured electrocardiogram and pulse wave to obtain the pulse wave transmission time and pulse wave analysis information, the obtained pulse wave transmission time, pulse wave analysis information, by the subject By calculating the diastolic blood pressure value based on the information on the physical characteristics of the subject, environmental information, and systolic blood pressure, there is an effect of providing a generalized regression equation applicable to the subjects.

Those skilled in the art will appreciate that various modifications and variations can be made without departing from the essential features of the present invention. Accordingly, the embodiments disclosed in the present invention are not intended to limit the technical spirit of the present invention but to describe the present invention, and the scope of the technical idea of the present invention is not limited by these embodiments. The protection scope of the present invention should be interpreted by the following claims, and all technical ideas within the equivalent scope should be interpreted as being included in the scope of the present invention.

Claims (17)

Obtaining pulse wave propagation time based on the electrocardiogram and pulse wave measured from the subject, and obtaining systolic blood pressure values based on the obtained pulse wave propagation time; Applied to the regression equation based on the obtained systolic blood pressure value, the obtained pulse wave propagation time, analysis information of the pulse wave, body characteristic information of the subject input by the subject, and environmental information measured at the electrocardiogram and pulse wave measurement And obtaining a diastolic blood pressure value. The method of claim 1, wherein the pulse wave transmission time, And a time difference between the time at which the peak value of the R-wave of the electrocardiogram appears and the time at the point at which the predetermined value of the pulse wave appears. The method of claim 1, wherein the systolic blood pressure value, The blood pressure measurement method, characterized in that inversely proportional to the square of the obtained pulse wave transmission time. According to claim 1, The analysis information of the pulse wave, And at least one of peak values of the second derivative waveform of the pulse wave. The method of claim 4, wherein the analysis information of the pulse wave, Blood pressure measuring method comprising the degree of vascular aging. The method of claim 5, wherein the degree of vascular aging, Equation 1

Where a, b, c, and d are obtained by obtaining a first peak value, a second peak value, a third peak value, and a fourth peak value from a waveform obtained by secondly deriving the measured pulse wave; And a constant value set to a value corresponding to the obtained peak values. The method of claim 1, wherein the input body characteristic information of the subject to be measured, And at least one of height, weight, age, and gender of the subject. The method of claim 1, wherein the environmental information, And at least one of a temperature, humidity, and air pressure around the subject measured during electrocardiogram and pulse wave measurement. According to claim 1, wherein the regression equation of the diastolic blood pressure, Equation 2

Obtained by, wherein C1 to C6 is a blood pressure measuring method, characterized in that the constant obtained through the regression analysis. A sensor unit for measuring the electrocardiogram and pulse wave of the subject; Obtaining the pulse wave delivery time based on the measured electrocardiogram and pulse wave, obtaining the systolic blood pressure value based on the obtained pulse wave delivery time, the obtained systolic blood pressure value, the obtained pulse wave delivery time, the analysis information of the pulse wave, the subject And a controller for applying a regression equation to obtain a diastolic blood pressure value based on the body characteristic information of the subject and the environmental information measured at the time of measuring the electrocardiogram and pulse wave. The method of claim 10, And an output unit configured to output at least one of systolic blood pressure values and diastolic blood pressure values calculated by the controller. The method of claim 11, And a storage unit for storing at least one of systolic blood pressure values and diastolic blood pressure values calculated by the controller. The method of claim 10, wherein the control unit, And the systolic blood pressure value having a feature inversely proportional to the square of the pulse wave propagation time. The method of claim 10, wherein the control unit, And at least one of the peak value of the second derivative waveform of the pulse wave or the degree of vascular aging. The method of claim 10, wherein the control unit, And at least one of the height, weight, age, and gender of the subject, using physical characteristic information of the subject. The method of claim 10, wherein the control unit, And at least one or more of the environment information of the temperature, humidity, and atmospheric pressure around the subject to be measured when the ECG and pulse wave are measured. The regression equation of claim 10, wherein the control unit uses the regression equation to obtain a diastolic blood pressure value. The pulse wave propagation time, pulse wave analysis information, body characteristic information, environmental information, systolic blood pressure values are respectively multiplied by coefficients obtained through regression analysis, and the pulse wave propagation time multiplied by the respective coefficients, pulse wave analysis information, body characteristic information, environment A blood pressure measuring device comprising information and a systolic blood pressure value.

Images