KR20080046793A - Anti-aging cosmetic composition comprising the extract of euphoria longana as active ingredient - Google Patents

Abstract

An extract of Euphoria longana is provided to activate skin cells and promote synthesis of skin cell proteins such as collagen, thereby improving skin wrinkles and promoting skin elasticity. A cosmetic composition for anti-aging comprises 0.00001-30 wt.% of an extract of Euphoria longana as an effective ingredient, wherein the extract is prepared by using a solvent selected from the group consisting of water, C1-4 alcohol, acetone, ethyl acetate, butyl acetate, 1,3-butylene glycol and chloroform. The composition is formulated into solution, suspension, emulsion, paste, gel, cream, lotion, powder, surfactant-containing cleansing oil, powdery foundation, emulsion foundation, wax foundation or spray. Further, the extract of Euphoria longana is extracted using ethanol.

Description

Anti-aging Cosmetic Composition Comprising the Extract of Euphoria longana as Active Ingredient}

The present invention relates to a cosmetic composition for preventing skin aging containing Euphoria longana extract as an active ingredient.

Wrinkles in the skin are the most pronounced skin aging manifestations caused by endogenous factors such as age and stress, or external environmental factors such as air pollution or ultraviolet radiation. Wrinkles occur on the face, neck, neck, elbows, armpits, hands, and feet on the forehead, around the eyes, between the legs, and around the mouth. Most are noticeable around 30 years of age, and their number, depth and range increase with age. The main cause of wrinkle formation is that reactive oxygen species generated in skin tissues by skin aging process form crosslinks in collagen fibers and elastic fibers, which occupy most of the skin dermis constituents, and change the formation and decomposition of these fibers. (Clinics in geriatric medicine, 2001, 17 (4): 617-630).

Antioxidants such as vitamin E, beta-carotene, vitamin C, and glutathione used to inhibit skin aging, and substances that enhance dermal collagen synthesis, such as radical scavengers and vitamin A, have been used to date It has been used as a substance to improve wrinkles.

However, most of these cosmetic active ingredients have strong skin irritation or are unstable in the formulation itself, resulting in discoloration, discoloration and precipitation, and decrease inherent activity of raw materials.

 In general, in order to prevent aging, a method of promoting collagen synthesis using a substance having an antioxidant effect or using a substance such as retinol or vitamin C has been used. However, these materials are poor in stability and have many problems in safety. Recently, many studies have been conducted to develop anti-aging materials from natural products. The present invention also has the feature of suppressing skin aging by improving the wrinkles caused by aging by using an active ingredient separated from natural products for this purpose.

The present invention is to develop a cosmetic composition for preventing skin aging containing an extract of Euphoria longana which is a deciduous tree and a deciduous arbor plant. Preferably, to develop a skin anti-aging cosmetic composition containing a material extracted from the fruit of the longan. Long eye extract is a very excellent effect of promoting collagen synthesis, very active cell activity and excellent effect of promoting the synthesis of useful skin proteins, in the present invention to prevent the aging by inhibiting the formation of skin wrinkles using the long eye extract It was.

The present invention provides a cosmetic composition for preventing skin aging containing an extract of Yongan, which is a deciduous tree and a deciduous tree, as an active ingredient.

The present invention is a cosmetic composition having a feature of inhibiting skin aging by promoting the generation of collagen in the dermal layer wrinkles caused by skin aging. In addition, in the present invention, the long eye extract has a feature of strengthening the matrix structure of the dermal layer by promoting synthesis of various proteins in skin cells.

An active ingredient ( Euphoria longan ) included in the composition of the present invention is a non-patient plant growing in the tropics. Leaves are alternate, thick, long oval, 15-45cm long, with flat edges. Flowers are yellowish white in April, with a scent of 3-6cm in diameter, with about 1,000 flowers hanging on the cone.

As used herein, the term 'yongan extract' refers to an extract obtained from various organs (eg, leaves, flowers, stems, fruits and roots, etc.) of the longan, and preferably means an extract obtained from the fruit of the longan.

In the present invention, the longan extract may be prepared in various extraction solvents, such as (a) water, (b) anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms (methanol, ethanol, propanol, butanol, etc.), (c) acetone, (d) Ethyl acetate, (e) butyl acetate, (f) 1,3-butylene glycol or (g) chloroform can be obtained from the solution using an extraction solvent, preferably an aqueous alcohol solution, more preferably 70% ethyl alcohol It can be obtained as a solvent. On the other hand, it will be apparent to those skilled in the art that the extract of the present invention can be obtained not only the above-described extraction solvent but also long-acting extract having substantially the same effect using other extraction solvents.

According to a preferred embodiment of the present invention, the content of the long-eye extract is 0.00001 to 30% by weight, preferably 0.0001 to 20% by weight relative to the dry weight of the composition. If the content is less than the expected effect is difficult to appear, if the content is exceeded there is a problem in color and appearance in the cosmetic formulation.

The ingredients included in the cosmetic composition of the present invention include ingredients commonly used in cosmetic compositions in addition to the long-eye extract as active ingredients, and include, for example, conventional auxiliaries such as antioxidants, stabilizers, solubilizers, vitamins, pigments and flavorings, and Carrier.

Cosmetic compositions of the present invention may be prepared in any formulation conventionally prepared in the art, including, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing cleansing , Oils, powder foundations, emulsion foundations, wax foundations and sprays, and the like, but are not limited thereto. More specifically, it may be prepared in the form of a flexible lotion, nutrition lotion, nutrition cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray or powder.

When the formulation of the present invention is a paste, cream or gel, animal carriers, vegetable oils, waxes, paraffins, starches, trachants, cellulose derivatives, polyethylene glycols, silicones, bentites, silicas, talc or zinc oxide are used as carrier components. Can be.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used, in particular, in the case of a spray, additionally chlorofluorohydrocarbon, propane Propellant such as butane or dimethyl ether may be included.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 Fatty acid esters of, 3-butylglycol oil, glycerol aliphatic ester, polyethyleneglycol or sorbitan.

When the formulation of the present invention is a suspension, a liquid diluent such as water, ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, and microcrystals are used as carrier components. Soluble cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component is aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide. Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters and the like can be used.

 The preparation method of the long eye extract contained in the anti-aging cosmetics of the present invention is as follows. The fruit of longan is washed with purified water, dried and crushed into small pieces, followed by 1-10 times the dry weight of water, 1-4 anhydrous or hydrous lower alcohols, acetone, ethyl acetate, butyl acetate or 1 , 3-butylene glycol, chloroform and the like are added. After cooling condenser is installed to prevent evaporation of the active ingredient in the state to extract 3-20 hours at 40-100 ℃, or extract for 1-15 days at 4-40 ℃ is prepared by drying completely with a rotary vacuum evaporator . In this case, since 1, 3-butylene glycol is difficult to dry using a rotary vacuum evaporator, the extraction loss is directly adjusted to 1% (w / v) after extraction under the above conditions, and used in the present invention for improving wrinkles.

The cosmetic composition of the present invention exhibits the effect of preventing skin aging. The long eye extract included in the cosmetic composition of the present invention exhibits collagen synthesis promoting effect and protein biosynthesis enhancing effect, thereby preventing aging of the skin. This fact is specified in detail in the following examples.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, and it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples according to the gist of the present invention. .

Preparation Example 1 Preparation of Longan Extract

Longan extract contained in the cosmetic composition of the present invention was prepared as follows. : First, wash with purified water, dry 200g of dried longan fruit in 1.2L of water, and extract by heating at 70-90 ℃ for 5 hours in the extractor equipped with cooling condenser, filter with 300 mesh filter cloth, and filter at 7-10 ℃. After aging for 10 days, the resultant was filtered with Whatman 5 filter paper. The filtrate was dried at 65 ° C. with a rotary light evaporator to obtain a dry weight of 11.8 g.

Preparation Example 2 Preparation of Longan Extract

After washing with purified water, 200g of dried longan fruit was poured into 1.2L of water, extracted at 15-35 ° C. for 5 days, filtered through a 300 mesh filter cloth, filtered with a filter of Wattman 5, and concentrated twice with a rotary vacuum evaporator. . 0.6L of 100% ethanol was added thereto, left at 5-10 ° C. for 7-10 days to mature, and then filtered through Whatman No. 5 filter paper. The filtrate was dried at 65 ° C. with a rotary immersion evaporator to obtain a dry weight of 12.5 g.

Preparation Example 3 Preparation of Longan Extract

Washed with purified water and dried 200g of dried longan fruit in 1.2L of water, extracted at 4-40 ° C for 5 days, filtered through 300 mesh filter cloth, and left to mature at 5-10 ° C for 7-10 days to ripen. Filtered. The filtrate was dried at 65 ° C. with a rotary light evaporator to obtain a dry weight of 11.5 g.

Preparation Example 4-21 Preparation of Longan Extract

Extraction was carried out in the same manner as in Preparation Example 3, and the results are shown in Table 1.

Experimental result of Preparation Example 4-21 Extraction solvent Dry weight of the final extract (unit: g) Preparation Example 4 10% ethanol 10.8 Preparation Example 5 20% ethanol 10.9 Preparation Example 6 30% ethanol 11.2 Preparation Example 7 40% ethanol 11.4 Preparation Example 8 50% ethanol 11.2 Preparation Example 9 60% ethanol 11.5 Preparation Example 10 70% ethanol 11.7 Preparation Example 11 80% ethanol 11.3 Preparation Example 12 90% ethanol 11.6 Preparation Example 13 100% ethanol 11.5 Preparation Example 14 Methanol 11.4 Preparation Example 15 n-propanol 9.5 Preparation Example 16 Isopropanol 9.6 Preparation Example 17 2-butanol 9.3 Preparation Example 18 Acetone 9.5 Preparation Example 19 chloroform 9.4 Preparation Example 20 Ethyl acetate 9.5 Preparation Example 21 Butyl acetate 9.6

Preparation Example 22 Preparation of Longan Extract

After washing with purified water and putting 200g of dried longan fruit into 1.2L 1,3-butylene glycol, extracting for 48 hours, filtering with 300 mesh filter cloth, leaving it to stand at 5-10 ℃ for 7-10 days to mature, and then watman 5 times. It filtered with filter paper. The extract was again dried to obtain a final concentration of 1% (w / v).

Preparation Example 23 Preparation of Longan Extract

After washing with purified water, 200g of dried longan fruit was added to 1.2L of 10% ethanol, and extracted by heating in an extractor equipped with a cooling condenser for 5 hours, filtered through 300 mesh filter cloth, and left to mature at 5-10 ° C for 7-10 days. After that, the filter was filtered by Whatman five times. This extract was dried at 65 ° C. with a rotary vacuum evaporator to obtain a dry weight of 12.3 g.

Preparation Example 24-32 Preparation of Longan Extract

Extraction was carried out in the same manner as in Preparation Example 23, and the results are shown in Table 2.

Experimental result of Preparation Example 24-32 Extraction solvent Dry weight of the final extract (unit: g) Preparation Example 24 20% ethanol 12.4 Preparation Example 25 30% ethanol 12.6 Preparation Example 26 40% ethanol 12.8 Preparation Example 27 50% ethanol 12.5 Preparation Example 28 60% ethanol 12.2 Preparation Example 29 70% ethanol 12.5 Preparation Example 30 80% ethanol 12.3 Preparation Example 31 90% ethanol 12.3 Preparation Example 32 100% ethanol 12.0

Experimental Example 1: Cell Activity Enhancement Effect of Longan Extract

The effect of enhancing cell activity on the extract of Longan prepared in Preparation Example 1-32 is obtained as follows. In this case, the longan extract was used after dissolving the longan powder prepared in Preparation Example in 1,3-butylene glycol to 1% (w / v).

Longan extract is used in the experiment to each 100㎛ / ㎖. The experiment was first inoculated human normal fibroblasts to 1 x 10 ⁴ cells in each well of 96-well microplate, and incubated for 48 hours at 37 ℃ in DMEM medium. Subsequently, the experimental group replaced with DMEM medium containing 2.5% of serum and the control group replaced with DMEM medium containing 2.5% of serum containing no ophthalmic extract for 24 hours at the final concentration of the extract of elongated eye at 100 µg / ml. Incubated with After incubation, the cell activity rate is determined by MTT assay to see the cell viability in each well. The cell activity rate is calculated by the following formula.

Cell Activity Effect of Longan Extract (Experimental Concentration 100㎍ / ㎖) Test substance Cell activity rate (%) Test substance Cell activity rate (%) Preparation Example 1 38.5 Preparation Example 17 42.5 Preparation Example 2 39.6 Preparation Example 18 42.8 Preparation Example 3 35.8 Preparation Example 19 44.3 Preparation Example 4 36.7 Preparation Example 20 41.5 Preparation Example 5 35.8 Preparation Example 21 40.7 Preparation Example 6 37.8 Preparation Example 22 45.8 Preparation Example 7 38.6 Preparation Example 23 36.5 Preparation Example 8 39.7 Preparation Example 24 35.3 Preparation Example 9 41.2 Preparation Example 25 33.5 Preparation Example 10 43.5 Preparation Example 26 38.5 Preparation Example 11 44.5 Preparation Example 27 45.3 Preparation Example 12 44.5 Preparation Example 28 44.5 Preparation Example 13 44.3 Preparation Example 29 43.2 Preparation Example 14 45.3 Preparation Example 30 41.2 Preparation Example 15 46.8 Preparation Example 31 40.3 Preparation Example 16 46.7 Preparation Example 32 42.3

Experimental Example 2: Collagen Synthesis Enhancement Effect of Longan Extracts

Human normal fibroblasts were seeded to 1 x 10 ⁶ cells in each well of a 48-well microplate and incubated for 24 hours at 37 ° C. in DMEM medium. Subsequently, the experimental group replaced with serum-free DMEM medium and the control group replaced with serum-free DMEM medium containing no ophthalmic extract were further cultured for 24 hours. After incubation, the supernatant of each well was collected and the amount of newly synthesized collagen was measured using a procollagen type I C-peptide (PICP) kit (Takara, Japan). PICP amount was converted to ng / ㎖, collagen biosynthesis increase rate was calculated by the following formula and the results are shown in Table 4.

Collagen Synthesis Enhancement Effect of Longan Extracts Test substance Collagen production increase rate (%) Test substance Collagen production increase rate (%) Preparation Example 1 80.5 Preparation Example 17 82.2 Preparation Example 2 81.3 Preparation Example 18 82.5 Preparation Example 3 82.5 Preparation Example 19 83.5 Preparation Example 4 82.2 Preparation Example 20 82.6 Preparation Example 5 80.2 Preparation Example 21 81.2 Preparation Example 6 81.5 Preparation Example 22 82.3 Preparation Example 7 81.6 Preparation Example 23 81.6 Preparation Example 8 89.9 Preparation Example 24 82.5 Preparation Example 9 83.3 Preparation Example 25 81.3 Preparation Example 10 82.5 Preparation Example 26 83.5 Preparation Example 11 84.5 Preparation Example 27 82.2 Preparation Example 12 82.2 Preparation Example 28 81.3 Preparation Example 13 81.2 Preparation Example 29 87.5 Preparation Example 14 82.0 Preparation Example 30 84.8 Preparation Example 15 83.2 Preparation Example 31 83.5 Preparation Example 16 84.3 Preparation Example 32 85.5

Experimental Example 3: Protein Synthesis Enhancement Effect of Longan Extract

Human normal fibroblasts were seeded to 1 x 10 ⁶ cells in each well of a 48-well microplate and incubated for 24 hours at 37 ° C. in DMEM medium. Subsequently, the experimental group replaced with serum-free DMEM medium and the control group replaced with serum-free DMEM medium containing no ophthalmic extract were further cultured for 24 hours. After incubation, the supernatant of each well was collected and the amount of newly synthesized protein was measured using a BioRad Protein assay kit. Protein amount was converted to mg / ㎖, protein biosynthesis increase rate was calculated by the following formula and the results are shown in Table 5.

Protein Synthesis Enhancement Effect of Longan Extract Test substance % Increase in protein production Test substance % Increase in protein production Preparation Example 1 81.8 Preparation Example 17 88.5 Preparation Example 2 82.5 Preparation Example 18 86.3 Preparation Example 3 82.2 Preparation Example 19 84.5 Preparation Example 4 80.2 Preparation Example 20 83.8 Preparation Example 5 81.5 Preparation Example 21 82.5 Preparation Example 6 81.8 Preparation Example 22 87.2 Preparation Example 7 82.3 Preparation Example 23 80.6 Preparation Example 8 84.5 Preparation Example 24 81.5 Preparation Example 9 81.3 Preparation Example 25 82.3 Preparation Example 10 82.5 Preparation Example 26 85.2 Preparation Example 11 82.7 Preparation Example 27 83.5 Preparation Example 12 83.2 Preparation Example 28 84.3 Preparation Example 13 82.3 Preparation Example 29 85.3 Preparation Example 14 83.5 Preparation Example 30 87.8 Preparation Example 15 84.5 Preparation Example 31 86.5 Preparation Example 16 84.7 Preparation Example 32 85.5

Hereinafter, based on the results of the above test examples, a cosmetic composition containing the long-eye extract is presented. However, the composition of the present invention is not limited to the following formulation examples.

Prescription 1: Softener

 The prescription example of the flexible cosmetics in the cosmetics containing the long-eye extract is as follows.

ingredient Content (unit: weight%) Longan Extract Glycerin 1.3-Butylene Glycol Fiji 1500 Allantoin DL-Pantenol E.D.T.A-2NA Benzophenone-9 Sodium Hyaluronate Ethanol Octicdodeceth-16 Polysorbate 20 Preservative, Flavor, Pigment Distilled Water 2.0 5.0 3.0 1.0 0.1 0.3 0.02 0.04 5.0 10.0 0.2 0.2 Sum 100

Prescription Example  2: convergence makeup

 Prescription examples of astringent cosmetics in cosmetics containing long eye extract are as follows.

ingredient Content (unit: weight%) Longan Extract Glycerin 1.3-Butylene Glycol Allantoin DL-Pantenol E.D.T.A-2NA Benzophenone-9 Sodium Hyaluronate Ethanol Polysorbate 20 Witch Hazel Extract Citric Acid Preservative, Flavor, Colorant Distilled Water 2.0 2.0 2.0 0.2 0.2 0.02 0.04 3.0 15.0 0.3 2.0      Sum 100

Prescription Example  3: Nutrition

 A prescription example of nutrient fluid in cosmetics containing a long eye extract is as follows.

ingredient Content (unit: weight%)      Longan Extract Glyceryl Stearate SE Stearyl Alcohol Lanolin Polysorbate 60 Solbitan Stearate Cured Vegetable Oil Mineral Oil Squalane Trioctanoin Dimethicone Tocopherol Carboxyvinyl Polymer Glycerin 1.3-Butylene Glycol Sodium Hyaluronate Tri Ethanolamine Preservative Pigmented distilled water 2.0 1.5 1.5 1.5 1.3 0.5 1.0 5.0 3.0 2.0 0.8 0.5 0.12 5.0 3.0 5.0 0.12 Sum 100

Prescription Example  4: nutrition cream

 Prescription example of nutrition cream in cosmetics containing longan extract is as follows.

ingredient Content (unit: weight%)      Longan extract lipophilic monostearate glycerine cetearyl alcohol stearic acid beeswax polysorbate 60 sorbitan stearate cured vegetable oil squalane mineral oil trioctanoin dimethicone sodium magnesium silicate glycerin betaine triethanolamine sodium hyaluronate preservative, fragrance, pigment distilled water 2.0 2.0 2.2 1.5 1.0 1.5 0.6 1.0 3.0 5.0 5.0 1.0 0.1 5.0 3.0 1.0 4.0 Sum 100

Prescription Example  5: Massage cream

 A prescription example of a massage cream in a cosmetic containing a long eye extract is as follows.

ingredient Content (unit: weight%)      Longan extract lipophilic monostearic acid glycerin stearyl alcohol stearic acid polysorbate 60 sorbitan stearate isostearyl isosterate squalane mineral oil dimethicone hydroxyethyl cellulose glycerin triethanolamine preservative, fragrance, pigment distilled water 2.0 1.5 1.5 1.0 1.5 0.6 5.0 5.0 35.0 0.5 0.12 6.0 0.7 Micro balance Sum 100

Prescription 6: Essence

 Prescription examples of essences in cosmetics containing a long eye extract is as follows.

ingredient Content (unit: weight%) Longan Extract Glycerine Betaine Fiji 1500 Allantoin DL-Pantenol E.D.T-2A Benzophenone -9 Hydroxyethyl Cellulose Sodium Hyaluronate Carboxyvinyl Polymer Triethanolamine Octyldodecanol Octyldodeces -16 Ethanol Preservative , Incense, pigment distilled water 2.0 10.0 5.0 2.0 0.1 0.3 0.02 0.04 0.1 8.0 0.2 0.18 0.3 0.4 6.0 Sum 100

Prescription Example  7: pack

A prescription example of a pack in a cosmetic containing a long eye extract is as follows.

ingredient Content (unit: weight%) Longan Extract Polyvinyl Alcohol Cellulose Gum Glycerin Fiji 1500 Cyclostrin DL- Panthenol Allantoin Glyciric Acid Monoammonium Nicotinamide Ethanol Fiji 40 Hardened Castor Oil Flavor, Pigment, Preservative Distilled Water 2.0 15.0 0.15 3.0 2.0 0.15 0.4 0.1 0.3 0.5 6.0 0.3 Micro balance Sum 100

Experimental Example 4: Evaluation of the wrinkle improvement effect of the cosmetic containing the long-eye extract

    The wrinkle improvement effect of the cosmetics of this invention was evaluated through the actual use test. A nutrition cream containing 2% (v / v) of the formulation of the long-eye extract of Formulation 4 and a cream in which the long-eye extract was replaced with purified water in Formula 4 were used. Twenty 30-40 year old women were randomly divided into two groups, and the creams of Formulation 4 and Comparative Example were washed twice every morning and then the appropriate amount of cream was applied continuously for 2 months around the eyes. Wrinkle improvement effect of each subject was evaluated through visual observation. The experimental results are shown in Table 13 below.

Wrinkle improvement effect (visual evaluation) of the cosmetics of the present invention Wrinkle improvement Effectiveness Great slightly none Cream of prescription example 4 14 3 3 85.0 Comparative cream 3 2 15 25.0

   According to the experimental results, the cosmetic composition of the present invention containing the long-eye extract showed a higher anti-wrinkle effect than the comparative example, the skin irritation could not be observed in the subjects of the cosmetic composition of the present invention applied to the skin.

The present invention provides an anti-aging cosmetic composition containing the long-eye extract as an active ingredient. The cosmetic composition of the present invention promotes collagen synthesis and promotes skin cell protein synthesis to effectively improve wrinkles caused by aging. As a result, it has a feature of preventing skin aging. Longan extract also has the feature of solving the skin problems caused by aging by activating skin cells. In conclusion, the present invention has a feature to improve the skin wrinkles caused by aging as a cosmetic composition containing the long-eye extract and to make the skin healthy.

As described above in detail certain parts of the present invention, it is apparent to those skilled in the art that these specific descriptions are merely preferred embodiments, and thus the scope of the present invention is not limited thereto. Therefore, the substantial scope of the present invention will be defined by the appended claims and equivalents thereof.

Claims (5)

A cosmetic composition for preventing skin aging, characterized in that it contains Euphoria longana extract as an active ingredient. The method of claim 1, wherein the long-acting extract is (a) water, (b) anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms, (c) acetone, (d) ethyl acetate, (e) butyl acetate, (f) 1 A skin composition for preventing skin aging, which is extracted using a solvent selected from the group consisting of, 3-butylene glycol and (g) chloroform as an extraction solvent. The cosmetic composition for preventing skin aging according to claim 2, wherein the extract of the long eye is extracted using ethanol, and has an excellent collagen synthesis effect, promotes protein synthesis, and promotes cell activity. The cosmetic composition for preventing skin aging according to claim 1, wherein the content of the long eye extract is 0.00001-30% by weight based on the total weight of the composition. The composition of claim 1 wherein the composition is from the group consisting of solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing cleansing oils, powder foundations, emulsion foundations, wax foundations and sprays. Cosmetic composition for preventing skin aging, characterized in that it has a formulation selected.