KR20070004792A - 아데노신 수용체 작용제 - Google Patents

아데노신 수용체 작용제 Download PDF

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Publication number
KR20070004792A
KR20070004792A KR1020067020304A KR20067020304A KR20070004792A KR 20070004792 A KR20070004792 A KR 20070004792A KR 1020067020304 A KR1020067020304 A KR 1020067020304A KR 20067020304 A KR20067020304 A KR 20067020304A KR 20070004792 A KR20070004792 A KR 20070004792A
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South Korea
Prior art keywords
compound
pain
adenosine
disease
subject
Prior art date
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Ceased
Application number
KR1020067020304A
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English (en)
Korean (ko)
Inventor
마틴 프리처드
재클린 오즈만
에드워드 세이보리
자일스 브라운
Original Assignee
캠브리지 바이오테크놀로지 리미티드
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Publication date
Priority claimed from GB0405012A external-priority patent/GB0405012D0/en
Priority claimed from PCT/GB2004/000902 external-priority patent/WO2004079329A2/en
Priority claimed from GBGB0405009.2A external-priority patent/GB0405009D0/en
Priority claimed from GB0412261A external-priority patent/GB0412261D0/en
Priority claimed from GB0412262A external-priority patent/GB0412262D0/en
Priority claimed from GB0413627A external-priority patent/GB0413627D0/en
Priority claimed from GB0419718A external-priority patent/GB0419718D0/en
Priority claimed from GB0420063A external-priority patent/GB0420063D0/en
Priority claimed from GB0420615A external-priority patent/GB0420615D0/en
Application filed by 캠브리지 바이오테크놀로지 리미티드 filed Critical 캠브리지 바이오테크놀로지 리미티드
Publication of KR20070004792A publication Critical patent/KR20070004792A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
KR1020067020304A 2004-03-05 2005-03-04 아데노신 수용체 작용제 Ceased KR20070004792A (ko)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
GB0405009.2 2004-03-05
GB0405012.6 2004-03-05
GB0405012A GB0405012D0 (en) 2004-03-05 2004-03-05 Therapeutic compounds
PCT/GB2004/000902 WO2004079329A2 (en) 2003-03-07 2004-03-05 Identification of therapeutic compounds
WOPCT/GB2004/000902 2004-03-05
GBGB0405009.2A GB0405009D0 (en) 2004-03-05 2004-03-05 Analgesics
GB0412261.0 2004-06-02
GB0412262.8 2004-06-02
GB0412261A GB0412261D0 (en) 2004-06-02 2004-06-02 Analgesics
GB0412262A GB0412262D0 (en) 2004-06-02 2004-06-02 Use of compounds for the treatment of pain
GB0413627.1 2004-06-18
GB0413627A GB0413627D0 (en) 2004-06-18 2004-06-18 Analgesics
GB0419718A GB0419718D0 (en) 2004-09-06 2004-09-06 Therapeutic compounds
GB0419718.2 2004-09-06
GB0420063A GB0420063D0 (en) 2004-09-09 2004-09-09 Therapeutic compounds
GB0420063.0 2004-09-09
GB0420615A GB0420615D0 (en) 2004-09-16 2004-09-16 Therapeutic compounds
GB0420615.7 2004-09-16
PCT/GB2005/000800 WO2005084653A2 (en) 2004-03-05 2005-03-04 Adenosine receptor agonists

Publications (1)

Publication Number Publication Date
KR20070004792A true KR20070004792A (ko) 2007-01-09

Family

ID=34923594

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067020304A Ceased KR20070004792A (ko) 2004-03-05 2005-03-04 아데노신 수용체 작용제

Country Status (12)

Country Link
US (1) US20080221060A1 (https=)
EP (1) EP1749016A2 (https=)
JP (1) JP2007526291A (https=)
KR (1) KR20070004792A (https=)
AU (1) AU2005218997B2 (https=)
BR (1) BRPI0508488A (https=)
CA (1) CA2557285A1 (https=)
EA (2) EA014425B1 (https=)
MX (1) MXPA06010075A (https=)
NO (1) NO20064365L (https=)
SG (1) SG144146A1 (https=)
WO (1) WO2005084653A2 (https=)

Cited By (1)

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WO2014028080A1 (en) * 2012-08-16 2014-02-20 Thomas Jefferson University Treatment of prostate cancer and hematologic neoplasms

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EP1434782A2 (en) 2001-10-01 2004-07-07 University of Virginia Patent Foundation 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof
GB0228723D0 (en) 2002-12-09 2003-01-15 Cambridge Biotechnology Ltd Treatment of pain
WO2005107463A1 (en) * 2004-05-03 2005-11-17 University Of Virginia Patent Foundation Agonists of a2a adenosine receptors for treatment of diabetic nephropathy
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
JP2008519029A (ja) * 2004-11-08 2008-06-05 キャン−ファイト・バイオファーマ・リミテッド 加速骨吸収の治療的処置
GB0500785D0 (en) 2005-01-14 2005-02-23 Novartis Ag Organic compounds
CN1947717B (zh) * 2005-10-14 2012-09-26 卓敏 选择性抑制腺苷酸环化酶1的化合物在制备用于治疗神经性疼痛和炎性疼痛的药物中的应用
US20070183995A1 (en) * 2006-02-09 2007-08-09 Conopco, Inc., D/B/A Unilever Compounds useful as agonists of A2A adenosine receptors, cosmetic compositions with A2A agonists and a method for using the same
WO2007120972A2 (en) 2006-02-10 2007-10-25 University Of Virginia Patent Foundation Method to treat sickle cell disease
EP2322525B1 (en) 2006-04-21 2013-09-18 Novartis AG Purine derivatives for use as adenosin A2A receptor agonists
GB0607950D0 (en) 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607953D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
US8188063B2 (en) 2006-06-19 2012-05-29 University Of Virginia Patent Foundation Use of adenosine A2A modulators to treat spinal cord injury
AU2007263728A1 (en) 2006-06-27 2008-01-03 Biovitrum Ab (Publ) Adenosine derivatives for the treatment of pain
BRPI0713902A2 (pt) 2006-06-27 2012-11-27 Biovitrum Ab compostos terapêuticos
WO2008000743A2 (en) * 2006-06-27 2008-01-03 Biovitrum Ab (Publ) Novel 2',3'-methylidene acetyl adenosine prodrugs for use as prodrugs for adenosine receptor agonists
EP1889846A1 (en) 2006-07-13 2008-02-20 Novartis AG Purine derivatives as A2a agonists
EP1903044A1 (en) 2006-09-14 2008-03-26 Novartis AG Adenosine Derivatives as A2A Receptor Agonists
WO2009061516A1 (en) * 2007-11-08 2009-05-14 New York University School Of Medicine Medical implants containing adenosine receptor agonists and methods for inhibiting medical implant loosening
US8058259B2 (en) 2007-12-20 2011-11-15 University Of Virginia Patent Foundation Substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters as A2AR agonists
JP2011509305A (ja) * 2008-01-09 2011-03-24 ピージーエックスヘルス、リミテッド、ライアビリティー、カンパニー Ａ２ａｒアゴニストによる神経障害性疼痛の髄腔内治療
US20100160351A1 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
WO2010071865A1 (en) 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
US20120165285A1 (en) * 2009-07-09 2012-06-28 Peter Richardson Combined preparation for use as a medicament
WO2011032175A1 (en) 2009-09-14 2011-03-17 Nuon Therapeutics, Inc. Combination formulations of tranilast and allopurinol and methods related thereto
CA2783859A1 (en) * 2009-12-10 2011-06-16 Institute Of Materia Medica, Chinese Academy Of Medical Sciences N6-substituted adenosine derivatives and n6-substituted adenine derivatives and uses thereof
WO2011123518A1 (en) * 2010-03-31 2011-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Adenosine receptor agonists for the treatment and prevention of vascular or joint capsule calcification disorders
KR20140059246A (ko) 2011-09-22 2014-05-15 화이자 인코포레이티드 피롤로피리미딘 및 퓨린 유도체
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AU2005218997A1 (en) 2005-09-15
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WO2005084653A2 (en) 2005-09-15
AU2005218997B2 (en) 2012-05-10
NO20064365L (no) 2006-11-22
WO2005084653A3 (en) 2006-05-18
US20080221060A1 (en) 2008-09-11
EA200800538A1 (ru) 2008-06-30
JP2007526291A (ja) 2007-09-13
EA011099B1 (ru) 2008-12-30
MXPA06010075A (es) 2007-04-10
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BRPI0508488A (pt) 2007-07-31
CA2557285A1 (en) 2005-09-15

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