KR20060098033A - Antibiotic composition for leather - Google Patents

Abstract

The present invention relates to an antimicrobial composition for leather treatment. More specifically, methylbenzimidazol-2-yl carbamate (Carbendazim) is applied to leather, and its activity is higher than that of an existing antimicrobial composition for leather treatment. It is related to an environmentally friendly and economical antimicrobial composition for leather treatment by confirming that even more excellent and less moldy effect is exhibited.

 Leather Treatment, Antibacterial, Methylbenzimidazol-2-yl carbamate, Carbendazim, Mold Resistant, Eco-Friendly, Economical

Description

Antibiotic composition for leather treatment {Antibiotic composition for leather}

Figure 1 is a photograph showing the antimicrobial activity according to TCMTB and carbendazim concentration.

The present invention relates to an antimicrobial composition for leather treatment. More specifically, methylbenzimidazol-2-yl carbamate (Carbendazim) is applied to leather, and its activity is higher than that of an existing antimicrobial composition for leather treatment. It is related to an environmentally friendly and economical antimicrobial composition for leather treatment by confirming that even more excellent and less moldy effect is exhibited.

The materials that make up leather are mainly proteins, and the leather processing process takes more than 10 days in water, and the tanning process such as adding ammonium salts, phosphate compounds, surfactants, eggplants, etc., used in the leather process, can cause microbial growth. Optimal environmental conditions are formed, and especially in wet blue leather, microbial propagation can occur easily during distribution such as transport and storage in wet conditions for a long time.

This causes serious problems in the merchandise value of the leather, such as discoloration or staining of the leather, deterioration of the leather quality due to weakening of physical properties as well as damage to the appearance of the leather. Therefore, it can be said that the use of antibacterial agent in the leather process is essential.

The manufacturing process of leather can be divided into two stages, the first half and the second half.The first half process removes unnecessary substances such as salt, dirt, dust, blood, fat, and hair from raw hides and solves the tangle of leather fibers. It is a process performed in the field, and the latter process is a process in which the refined leather is subjected to an acid process called tanning.

In the first process, decay caused by bacteria, in the latter process, contamination by mold causes problems.

Currently used 2- (thiocyanomethylthio) benzothiazole (TCMTB) as an antibacterial agent for mold prevention, and the amount generally used is 30% of active ingredient TCMTB. 0.1 to 0.2% by weight is commonly used.

However, TCMTB is a class II toxicity (high toxicity) antimicrobial agent in the EPA classification and has a problem that the price is high leather processing cost is high. Therefore, there is an urgent need for research on antibacterial agents for leather treatment that can replace TCMTB.

On the other hand, methylbenzimidazol-2-yl carbamate (Carbendazim) is not easy to formulate due to its extremely low solubility in water or general organic solvents.

Accordingly, the present inventors studied the antimicrobial effect by treating various types of antimicrobial agents that have not been used in the leather manufacturing process to develop an antimicrobial agent that can replace the TCMTB that has been used as an antimicrobial agent for leather treatment. It was confirmed that methylbenzimidazol-2-yl carbamate (carbendazim) is less toxic than conventional TCMTB and is economical in terms of cost effectiveness because of its excellent antibacterial effect even at a lower throughput than leather weight. In addition, the present invention has been completed by formulating a carbendazine having low solubility in water and an organic solvent with a specific surfactant and formulating it in the form of a suspension concentrate to apply the carbendazine to leather.

Accordingly, an object of the present invention is to provide an antimicrobial composition for leather treatment containing 10 to 30% by weight of methylbenzimidazol-2-yl carbamate (carbendazim) as an active ingredient.

It is another object of the present invention to provide a method for treating the composition with leather.

The present invention is characterized by the antimicrobial composition for leather treatment containing 10 to 30% by weight of methylbenzimidazol-2-yl carbamate (carbendazim) as an active ingredient.

The present invention also includes a method of treating the composition to leather.

The present invention will be described in more detail as follows.

In the present invention, methylbenzimidazol-2-yl carbamate (Carbendazim) is applied to leather, which is more active than an existing antimicrobial composition for leather treatment and exhibits excellent antifungal effect even in a small amount. By confirming the environmentally friendly and economical antibacterial composition for leather treatment.

The present invention is characterized in that methylbenzimidazol-2-yl carbamate (carbendazim) having superior antibacterial activity and weak toxicity than TCMTB, an active ingredient that has been used as an antibacterial composition for leather treatment, is characterized by Formulation is carried out using specific amounts of excipients such as surfactants and stabilizers so that compaction is possible for leather treatment.

First, methylbenzimidazol-2-yl carbamate (carbendazim), which is an active ingredient of the antimicrobial composition of the present invention, was extremely difficult to be applied to leather treatment because of its low solubility in water and organic solvents. Another feature is that it is formulated in the form of a suspension concentrate using a specific amount of additives such as surfactants, stabilizers, antifoaming agents to be soluble in water. At this time, the carbendazim is preferably used 10 to 30% by weight based on the total antimicrobial composition. If less than 10% by weight, there is a problem that the antimicrobial effect is insignificant, if it exceeds 30% by weight it is uneconomical because no further antimicrobial effect is increased.

In addition, in the present invention, in order to prepare carbendazim as a liquid hydrating agent, a surfactant should be used to facilitate the wetting and dispersing of the active ingredient. Preferred surfactants include polyoxyethylene-polyoxypropylene copolymer and polyoxyethylene alkylaryl ether. It is preferable that the phosphate is mixed in a 20:80 weight ratio. The amount of the surfactant used may vary depending on the amount of carbendazim, the active ingredient in the composition, it is preferable to use 3 to 15% by weight.

In addition, the present invention uses an antifreeze to solve the low temperature freezing problem, it is preferable to use at least one of propylene glycol, ethylene glycol and the like as a preferred antifreeze. Its preferred content is 5 to 15% by weight in order to prevent freezing at -10 to -15 ℃.

In addition, the present invention uses a stabilizer to uniformly distribute the active ingredient in the composition over the long term, a preferred stabilizer is xanthan gum, the preferred content is 0.1 to 0.5% by weight. If the content thereof is less than 0.1% by weight, there is a problem in that the active ingredient is not uniformly distributed in the composition and precipitation occurs. If the content exceeds 0.5% by weight, the viscosity of the composition is rapidly increased, which causes problems in preparing and using the composition.

In addition, a defoaming agent is used to prevent foaming in the preparation of the composition, a preferred antifoaming agent is a silicone-based antifoaming agent, the preferred content is 0.1 to 0.3% by weight.

In addition, an additional fungicide is added to the composition, which is to prevent the growth of bacteria during product storage, and may be added 0.1 to 0.5% by weight of isothiazol-based bactericide.

By mixing water in the composition components to 100% by weight of the total composition can be prepared in the form of a liquid hydrating agent, it can be applied to leather as a liquid hydrating agent form.

In general, the antibacterial agent for the treatment of leather is mainly used in the pickling process and tanning process of the leather processing process.

Since the leather (wet blue) finished to the tanning process has some degree of preservation, in the leather process, the raw material blood is treated to wet blue and placed in the factory until the order is placed. It is essential. In addition, the mold antibacterial agent is treated in the dyeing process or eggplant process when the damage of the mold is concerned.

As for the throughput of the mold antimicrobial agent to be processed in the leather process, it is common to use the mold antimicrobial composition in an amount of 0.1 to 0.2% by weight of the leather.

When the antimicrobial composition containing the conventional TCMTB as an active ingredient is applied to leather treatment, it is not economically toxic as well as treating a large amount.

However, when using carbendazim as in the present invention, there is no toxicity concern and excellent antibacterial effect can be obtained even with a small throughput, which is very economical and environmentally friendly.

Therefore, the antimicrobial composition according to the present invention is preferably treated with a leather 100 ~ 1000 ppm relative to the weight of the active ingredient based leather in consideration of antimicrobial activity and economic efficiency. If the treatment is less than 100 ppm there is a problem that the antibacterial effect is insufficient, if it exceeds 1000 ppm it is economically inefficient.

In particular, it is preferable that the treatment of the composition on leather is applied by stray, immersion or the like.

In the present invention, the TCMTB and carbendazim currently used as a fungal antimicrobial agent were treated with the same amount of active ingredient to compare the antimicrobial effect between the two antimicrobial agents, and also various concentrations to determine the active ingredient amount of the carbendazim exhibiting the same or higher antimicrobial effect as TCMTB. The antimicrobial effect was tested.

Measurement of the antimicrobial effect, the antimicrobial agent by using a representative strain of Aspergillus duck material (Aspergillus oryza e), tricot der do not annuum (Trichoderma hazianum), Penny room Solarium sheet rinum (Penicillium citrinu m) generated in the leather The treated leather specimens were placed on a culture medium on which microorganisms were cultured, and the halo method was used to measure the size of the suppressed ring produced in mm by inhibiting the growth of microorganisms by an antimicrobial agent.

Accordingly, the present invention relates to the manufacturing process of the leather to prevent damage caused by the mold of the leather and to the production of a composition for preventing the mold during storage, the carbendazim EPA toxicity class IV toxicity (usually toxic) is much more environmental than conventional antimicrobial agents It is expected to be very useful industrially in terms of being friendly and economical, and in formulating this carbendazine in the form of a liquid concentrate (Spension concentrate) to enhance the competitiveness of the leather industry.

Hereinafter, the present invention will be described in more detail based on the following examples, but the present invention is not limited thereto.

Examples 1-4: Antibacterial Preparation

After adding an appropriate amount of water to the compounding tank, propylene glycol, a surfactant, an antifoaming agent was added and the carbendazim was added while stirring. And wet grinding with Mill. Then, mixed with a solution made of xanthan gum and water to prepare an antimicrobial agent of liquid concentrate (Suspension concentrate).

Division (weight%) Example 1 Example 2 Example 3 Example 4 Cavendazim 10 10 15 30 Surfactants CROPOL-SC305 ¹⁾ 5 5 8 12 Antifreeze Propylene glycol 7 7 7 10 stabilizator Xanthan Gum 0.3 0.3 0.3 0.5 Silicone Defoamer 0.1 0.1 0.1 0.2 additive Bacteriside 0 0.1 0.1 0.1 menstruum water 77.6 77.5 69.5 47.2  1) A surfactant in which a polyoxyethylene-polyoxypropylene copolymer and a polyoxyethylene alkylaryl ether phosphate are mixed in a 20:80 weight ratio

Test Example 1 Preparation and Activity of Antimicrobial Leather Specimen

The process of preparing leather specimens for testing the antibacterial effect of the antimicrobial agent and the TCMTB-containing antimicrobial composition prepared as in Example 1 after the leather treatment is a leather manufacturing process (salt-treated raw skin water process) commonly used in the leather industry. , Manufactured by the deliming process, the lysis process, the pickling process, and the oiliness process). At the last step of the pickling process of the existing leather treatment process, the leather specimen was prepared by treating 600 ppm of the active ingredient with respect to the raw material weight in the composition. Leather specimens were also treated with a mildew antimicrobial agent.

The medium used for the antimicrobial experiment was PDA (potato dextrose agar), and the medium was prepared and sterilized. Aspergillus oryza e, Trichoderma hazianum , Penicillium citrinu m Spores of the strain were formed and diluted in sterile distilled water to inoculate the spore suspension on the medium. The antimicrobial treated and antimicrobial treated specimens were placed on a medium and incubated in an incubator at 27 ° C. for 3 days, and then the length of the ring from which growth was suppressed from the leather specimens was measured.

The antimicrobial effect was obtained by an average of five repeated experiments, and the results are shown in Table 2 below.

division Size of restraint ring (unit: mm) Aspergillus oryzae Penicillium citrinum Trichoderma hazianum TCMTB 4.5 14 10.5 Example 1 12 29 10 Control (no treatment) 0 0 0

Test Example 2

In order to determine the proper amount of carbendazim (Carbendazim) using a leather specimen manufacturing process as in Test Example 1 to prepare a leather specimen treated with 100 ppm, 200 ppm, 300 ppm, 400 ppm and 600 ppm carbendazim, As a control, a specimen treated with 600 ppm of TCMTB was prepared.

The result of measuring the antimicrobial effect of the prepared leather specimens in the same manner as in Test Example 1 is shown in Table 3 below.

division Size of restraint ring (unit: mm) Aspergillus oryzae Penicillium citrinum Trichoderma hazianum Carbendazim 600 ppm Treatment 12 29 10 Carbendazim 400 ppm Treatment 12 25 10 Carbendazim 300 ppm Treatment 10 24 9 Carbendazim 200 ppm Treatment 8.5 23 8 Carbendazim 100 ppm Treatment 6 21 5 TCMTB 600 ppm processing 4 14.5 10

As described above, the antimicrobial composition according to the present invention is superior to the antimicrobial TCMTB-containing antimicrobial composition currently used by applying methylbenzimidazol-2-yl carbamate (Carbendazim) in leather treatment, and thus a small amount during leather processing. The same effect can be seen even if used, it is expected to be very useful because it is environmentally friendly and economical.

Claims (3)

Methylbenzimidazol-2-yl carbamate (Methylbenzimidazol-2-yl carbamate, carbendazim) Antibacterial composition for leather treatment, characterized in that it contains 10 to 30% by weight as an active ingredient. The antimicrobial composition of claim 1 wherein the antimicrobial composition is a liquid concentrate formulation. In the method of treating an antimicrobial composition to leather, Using the antimicrobial composition of claim 1 as the antimicrobial composition, a method of treating the leather with 100 to 1000 ppm relative to the weight of the leather on the basis of the active ingredient.

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