KR20040068054A - Composition for sterilizing with a continuous sterilizing effect - Google Patents

Abstract

PURPOSE: Provided is a bactericide composition which exerts excellent bactericidal effect, and is deeply absorbed into the fiber to make the bactericidal effect semi-permanently. CONSTITUTION: The bactericide composition comprises an oil-in-water type polymer emulsion with 35-45wt.% of solid content; and 0.5-5wt.% of bactericidal powder in relation to the polymer emulsion with 45-55wt.% of silicon dioxide, 8-12wt.% of aluminum oxide, 3-5wt.% of potassium hydroxide, 3-5wt.% of magnesium oxide, 25-30wt.% of boric acid, 3-5wt.% of manganese oxide, 2-3wt.% of ferrous oxide, 2-3wt.% of red oxide.

Description

Sterilization composition with continuous bactericidal ability {COMPOSITION FOR STERILIZING WITH A CONTINUOUS STERILIZING EFFECT}

The present invention relates to a bactericidal composition that is easy to use and has a sustained and excellent bactericidal power.

In the environment where we live, a myriad of bacteria are distributed, and because they are very fertile, the number of them grows exponentially when given the proper temperature and humidity, not only to cause odors and to impede the pleasant living environment. It causes various diseases in humans. In particular, various textile products that come in direct contact with the skin may cause various skin diseases by the propagation of bacteria or damage the fibers themselves. Therefore, it is very important to remove bacteria from various textile products, such as clothing and bedding, which directly or indirectly affect human hygiene for a healthy and comfortable life.

Typically, the following methods have been used for the removal of bacteria from fibers:

The first is heat sterilization. In general, most bacteria are susceptible to heat, so that the bacteria are killed by treating the fiber at a high temperature of 100 ° C. or higher, which is the most widely used method for sterilizing fibers. However, this method is disadvantageous because it must be treated at high temperatures, and therefore it is not applicable to dangerous and heat-sensitive fibers, and the fibers are easily damaged.

The second is sterilization using chemicals such as chlorine, CaOCl ₂ , H ₂ O ₂ , O ₃ However, this method has the disadvantage that the chemicals used are harmful to the human body and can discolor, discolor or damage the fibers.

The third is sterilization using ultraviolet rays, and since ultraviolet rays generally have the strongest sterilizing power at wavelengths around 260 to 280 nm, the fiber is sterilized by irradiation with ultraviolet rays in the above range. However, this method requires expensive special equipment and has a disadvantage in that it is cumbersome to perform.

In addition, all of the conventional methods for sterilizing fibers, including the above method, have only a temporary sterilization effect and the effect does not last for a long time. And, high sterilization power of more than 90% could not be guaranteed.

In order to solve this problem, the present invention aims to provide a liquid sterilizing composition which has a high sterilizing power of 95% or more and the sterilizing power is semipermanently maintained and can be easily applied to the fiber.

The present invention relates to a liquid sterilizing composition having a semi-permanent and excellent sterilizing effect.

More specifically, the present invention provides 45 to 55 parts by weight of silicon dioxide (SiO ₂ ) and 8 to 12 parts by weight of aluminum oxide (aluminum oxide, Al ₂ O ₃ ) in an oil-in-water type polymer emulsion. 3 to 5 parts by weight of potassium hydroxide (KOH), 3 to 5 parts by weight of magnesium oxide (MgO), 25 to 30 parts by weight of boric acid (H ₃ BO ₃ ), manganese oxide , 3 to 5 parts by weight of MnO, 2 to 3 parts by weight of ferrous oxide (FeO) and 2 to 3 parts by weight of ferrous tetraoxide (Red oxide, Fe ₄ O ₃ ), based on the weight of the water-soluble polymer emulsion To a sterilizing composition comprising in an amount of 0.1 to 5% by weight. Since the composition can be used in a liquid form that can be diluted and sprayed with water, the sterilization of the fiber can be easily performed by spraying and applying the fiber.

The water-soluble polymer emulsion has a solid content of about 35 to 45% by weight, and can be obtained using a polymer selected from the group consisting of polyurethane, epoxy, acyl, vinyl acetate and unsaturated polyester. In addition, the water-soluble polymer emulsion may further include an emulsifier and / or a surfactant and / or an organic solvent in order to facilitate the preparation of the emulsion, to make the binding of the polymer and the sterilizing powder and adsorption to the fiber more powerful. In addition, a binder and / or thickener may be additionally included. At this time, castor oil based on the amount of castor oil in the amount of 3 to 15% by weight, and surfactants commonly used as the surfactant in an amount of 3 to 15% by weight, as the organic solvent, for example, MEK (Methyl ethyl ketone) in an amount of 10 to 15% by weight of the organic solvent, the thickener, such as methylcellulose in an amount of 3 to 5% by weight, selected from the group consisting of emulsifiers commonly used as the binder 1 To 3% by weight.

The present inventors mixed silicon oxide, aluminum oxide, potassium hydroxide, magnesium oxide, boric acid, manganese oxide, ferrous oxide, and ferric tetraoxide in the same amounts, and then added to a glass melting furnace at 1350 to 1550 ° C. for 19 to 21 hours. After melting, the obtained melt mixture was poured into cooling water to finely pulverize the decomposed glassy particles to nano size to obtain a sterilizing powder having excellent sterilizing effect, which was named 'biotite'. It can be used as one kind of sterile powder included in the composition.

The bactericidal powder 'biotite' has a concentration of 1% as a test result of the Korea Testing Institute, 60.0% after 10 minutes for E. coli, 87.8% after 30 minutes, 51.7% after 10 minutes for Staphylococcus, 90.5 after 30 minutes It was found to exhibit a bactericidal effect of% (see Table 1). The bactericidal effect is assumed to be due to the far infrared rays emitted by the biotite, and the biotite of the present invention can continuously emit far infrared rays at room temperature, unlike the far infrared rays which are normally emitted by silicon oxide by heat. In addition, since the sterilizing composition is in the form of microparticles having an average particle diameter of 1 to 100 nm, it may be uniformly dispersed in an aqueous polymer emulsion to form a sterilizing composition.

In addition, the bactericidal composition of the present invention may further include at least one material selected from the group consisting of silver ions (Ag ⁺ ), zinc ions (Zn ²⁺ ), and platinum group elements. At this time, the content ratio of biotite, silver ions, zinc ions, and platinum group elements is 1: 0.01 to 4: 0.01 to 4: 0.001 to 0.5 (biotite weight: silver ion weight: zinc ion weight: platinum group element weight). Is preferably. The platinum group element may be selected from the group consisting of ruthenium (Ru), rhodium (Rh), palladium (Pd), osmium (Os), iridium (Ir) and platinum (Pt), in particular palladium or platinum Do. The composition range is defined to obtain the best sterilization effect as a result of repeated experiments. At this time, the platinum group elements are used in an ionized liquid state.

In general, all metals present on Earth are bactericidal, and the most known of them are the platinum group elements. Platinum element is a representative transition element, all belong to petroleum element, and its output is small, but it is a beautiful silver white (powder is black) as decorative precious metal, and its melting point is high and its specific gravity is high. In addition, chemical traits are inert and do not erode well to acids and alkalis. Ruthenium and osmium, rhodium and iridium, palladium and platinum are particularly similar in nature and are known as compounds that catalyze the reaction of various organic compounds. On the other hand, it is known that metal ions such as silver (Ag ⁺ ) or zinc (Zn ²⁺ ) also have bactericidal (antibacterial) or algae, and many developed countries such as Japan have regarded the sterilization and aid of silver against freshwater algae. Research is ongoing. These silver ions or zinc ions are expected to be of high value as a substitute for chlorine or other toxic microbicides because they have little toxicity to humans.

Thus, the sterilizing composition further comprising at least one substance selected from the group consisting of silver ions (Ag ⁺ ), zinc ions (Zn ²⁺ ) and platinum group elements in the biotite having excellent sterilizing ability has a more enhanced sterilizing effect ( See Table 2).

In addition, the bactericidal composition of the present invention may further include polyhexamethyleneguanidine phosphate in the biotite. At this time, it is preferable that the content ratio of biotite and polyhexamethyleneguanidine phosphate is 1: 0.01-2 (biotite weight: weight of polyhexamethyleneguanidine phosphate) by weight ratio. Polyhexamethyleneguanidine phosphate has a bactericidal effect against bacteria such as bacteria, yeast, and fungus and is almost nontoxic to humans. The sterilization composition additionally including polyhexamethyleneguanidine phosphate in biotite has an enhanced bactericidal effect. Indicates.

In addition, the bactericidal composition of the present invention may further include polyhexamethyleneguanidine phosphate and at least one material selected from the group consisting of silver ions (Ag ⁺ ), zinc ions (Zn ²⁺ ) and platinum group elements in the biotite. . At this time, the content ratio of each component is 1: 0.01-4: 0.01-4: 0.001-0.5: 0.01-2 (Biotite weight: Silver ion weight: Zinc ion weight: Platinum group element weight: Polyhexamethyleneguanidine phosphate Weight).

While the bactericidal composition of the present invention is harmless to the human body, it has not only an excellent bactericidal effect against various fungi such as various bacteria and yeasts, molds, algae, etc., but also has an extinction effect on mites.

The bactericidal composition of the present invention can be applied by diluting with water and spraying onto fibers. More specifically, when a diluent diluted about 5 to 10 times with water of the composition of the present invention is sprayed onto a fiber and dried, only a solid component combined with the polymer and the sterilizing powder in the sterilizing composition remains 99.9% higher for most bacteria. Show bactericidal power (see Table 3). In addition, the solid component remaining as the solvent evaporates is insoluble and strongly binds to and adsorbs on the fibrous tissue, so that it is not dissolved during washing or removed after washing.

In addition, since the sterilizing composition of the present invention can be used by spraying in the form of a dilution as described above, the fiber by a very simple and easy process of simply spraying the fiber into a nebulizer without spraying a cumbersome process or a separate apparatus There is an advantage that can be sterilized.

The bactericidal composition of the present invention comprises all animal or vegetable natural fibers, including nylon, polyester, acrylonitrile, polyvinyl alcohol, polyvinyl chloride, polyvinylidene chloride, polypropylene, polyurethane, including cotton, raw sand, wool, and the like. It is applicable to all fibers including the same synthetic fiber or a blend of natural fibers and synthetic fibers, and can be used for all fibers having a structure capable of adsorbing the solid components of the bactericidal composition of the present invention, such as plain weave, twill weave, and satin weave.

In addition, the sterilizing composition of the present invention, in addition to spraying directly to the fiber as described above, by spraying all the sites where bacteria grow or unpleasant smell can be obtained sterilization effect and odor removal effect. Specific examples to which the composition of the present invention may be applied are as follows:

Air conditioner (air intake internal filter); Kitchen utensils such as dish towels, scrubbers, cutlery and the like, and various odor generating parts of the kitchen; handkerchief; Shoes or shoe insoles; underclothing; Menstrual supplies; Sofa, bed mattress, cushion; Indoor odor generating part; Bedding such as blankets and duvets; Mask; Amount - say; Pillow; carpet; shoe closet; All places where fungi may live; Refrigerator, cold plate; Quilt; Behind the sheet; bathroom; Mop; Damp place; toy; diaper; Car seats and floors; Computer vending machines; Telephone handset; tablecloth; Inside and outside the sink; Glass window frames (with condensation); Towel; Ring cellar or cellar; trash can; Air purifier filters; Vacuum cleaner internal filter; Rubber gloves inside etc.

Hereinafter, the present invention will be described in more detail with reference to Examples, but the scope of the present invention is not limited to these Examples.

Example 1 Preparation of Sterile Powders (1) -Biotite

45 g of silicon oxide, 8 g of aluminum oxide, 3 g of potassium hydroxide, 3 g of magnesium oxide, 25 g of boric acid, 3 g of manganese oxide, 2 g of ferric oxide, and 2 g of ferric tetraoxide were placed in a mixing vessel and 0.5 rpm with a stirrer at 33 rpm. After mixing for 1 to 1 hour, the mixture is added to a glass melting furnace of 1350 to 1550 ° C. and melted for 19 to 21 hours. The molten mixture is added to cooling water to ball mill the decomposed glassy particles to a nano size. Grinding gave a powdered biotite.

Bactericidal test

Experiment apparatus

Incubators (Memmert, Germany)

Test strain

Escherichia coli (ATCC 25922)

Staphylococcus aureus (Staphylococcus aureus, ATCC 25923)

The test strain was shaken and cultured in a liquid heart (Brain Heart Infusion Broth), and the bacteria were diluted to adjust the initial inoculated bacteria to 1 to 9 x 10 ⁵ cfu / ml and used for the test. The cultured bacteria were inoculated in 100 ml of sterile physiological saline, and the initial bacterial counts were measured. Bacterial powder biotite obtained in Example 1 was added to 100 ml of physiological saline containing the bacteria so as to have a concentration of 1%, and the number of bacteria was measured after 10 minutes and 30 minutes. The number of bacteria was calculated by multiplying the number of bacteria on the medium by the dilution factor.

The test results are shown in Table 1 below. This test was performed by the Korea Testing Institute, Table 1 below is the result of the evaluation by the Korea Testing Institute.

Test strain Early 10 minutes later 30 minutes later E. coli 4.5 x 10 ⁵ 1.8 x 10 ⁵ (60%) * 5.5 x 10 ⁴ (87.8%) * S. aureus 6.0 x 10 ⁵ 2.9 x 10 ⁵ (51.7%) * 5.7 x 10 ³ (90.5%) *

Unit: CFU / ml

*: Reduction rate (%) = {(initial number of bacteria-number of bacteria after a certain time) / initial number of bacteria} x 100

As can be seen from the above results, the bactericidal powder biotite of the present invention had a concentration of 1% at 60.0% for E. coli after 10 minutes, 30 minutes at 87.8%, and 51.7% at 10 minutes for Staphylococcus. After 90.5% showed an excellent bactericidal effect. These results suggest that increasing the concentration of biotite or increasing the sterilization time can achieve a sterilization effect of nearly 100%.

Example 2: Preparation of Sterilized Powders (2)

To 10 g of the biotite prepared in Example 1, 15 g of silver ions, 15 g of zinc ions, and 3 g of palladium were mixed to prepare a sterile powder.

Bactericidal test

Experiment apparatus

Incubators (Memmert, Germany)

Test strain

Escherichia coli (ATCC 25922)

Staphylococcus aureus (Staphylococcus aureus, ATCC 25923)

The above strain was shaken and cultured in a liquid heart (Brain Heart Infusion Broth), and the bacteria were diluted to adjust the initial number of inoculated bacteria to 1 to 9 x 10 ⁵ cfu / ml. The cultured bacteria were inoculated in 100 ml of sterile physiological saline, and the initial bacterial counts were measured. In 100 ml of saline containing the bacterium, the bactericidal powder obtained in Example 2 was added at a concentration of 1% and 2%, respectively, and the number of bacteria in each case was measured after 10 minutes and 30 minutes. The number of bacteria was calculated by multiplying the number of bacteria on the medium by the dilution factor.

The test results are shown in Table 2 below. This test was carried out by the Korea Testing Institute, Table 2 below is the result of the evaluation by the Korea Testing Institute.

Test strain Sample classification Early 10 minutes later 30 minutes later E. coli One % 1.8 x 10 ⁵ 9.7 x 10 ⁴ (49.0%) * Not detected (100%) * 2 % 1.9 x 10 ⁵ Not detected (100%) * Not detected (100%) * S. aureus One % 3.7 x 10 ⁵ Not detected (100%) * Not detected (100%) * 2 % 4.0 x10 ⁵ Not detected (100%) * Not detected (100%) *

Unit: CFU / ml

*: Reduction rate (%) = {(initial number of bacteria-number of bacteria after a certain time) / initial number of bacteria} x 100

As can be seen from the above results, the bactericidal powder (2) of the present invention showed a bactericidal effect of 19.0 to 49.0% after 10 minutes to E. coli, but showed a bactericidal effect of 100% after 30 minutes, 2% In 10 minutes, the bactericidal effect was already 100%, and for Staphylococcus aureus, 1% and 2% showed 100% bactericidal effect after 10 minutes.

Example 3: Preparation of Bactericidal Compositions

A sterilizing composition was prepared by mixing an oil-in-water polyurethane emulsion having a solid content of 40% with 3 wt% of the sterilizing powder prepared in Example 2.

Sterilization Test 1

Using the bactericidal composition, the bactericidal power test was performed as follows in the Korea Testing Institute.

Inoculum: Standard cloth (cotton), 5 x 5 cm, as defined in KS K 0905

Test strain: Escherichia coli (ATCC 25922),

Staphylococcus aureus (Staphylococcus aureus, ATCC 25923).

Measure the initial bacterial count of the inoculum (5x5 cm cotton) inoculated with E. coli and Staphylococcus aureus, and treat the dilution diluted 5 times with the bactericidal composition in an amount of 1 ml / (inoculation), 30 The number of bacteria after minutes was measured and shown in Table 3 below.

Test strain Initial bacterial count (CFU / inoculation) Bacterial count after 30 minutes (CFU / inoculation) Reduction Rate * E. coli 3.2 x 10 ⁵ 60 99.9% S. aureus 1.2 x 10 ⁵ 40 99.9%

*% Reduction = {(initial number of bacteria-number of bacteria after a certain time) / (initial number of bacteria)} x 100

As can be seen from the above test results, the bactericidal composition of the present invention exhibited a high bactericidal power of 99.9% when applied to cotton fabrics.

Sterilization Test 2

Using the bactericidal composition, the bactericidal power test was performed as follows in the Korea Testing Institute.

Inoculum: Standard cloth (cotton), 5 x 5 cm, as defined in KS K 0905

Test strain: Escherichia coli (ATCC 25922),

Staphylococcus aureus (Staphylococcus aureus, ATCC 25923).

Measure the initial bacterial count of the inoculum (5x5 cm cotton) inoculated with E. coli and Staphylococcus aureus, and treat the dilution diluted 5 times with the bactericidal composition in an amount of 1 ml / (inoculation), 40 After drying for 12 hours at ℃, the number of bacteria after washing 10 times in a detergent-free state in a standard washing course was measured and shown in Table 4.

Test strain Initial bacterial count (CFU / inoculation) Bacterial count after 30 minutes (CFU / inoculation) Reduction Rate * E. coli 1.1x 10 ⁵ 5.2 x 10 ² 99.9% S. aureus 1.5x 10 ⁵ 5.4 x 10 ³ 96.4%

*% Reduction = {(initial number of bacteria-number of bacteria after a certain time) / (initial number of bacteria)} x 100

In order to eliminate the bactericidal effect by the detergent and to measure only the bactericidal effect by the bactericidal composition of the present invention, it was washed in a detergent-free state.

As can be seen from the above test results, the bactericidal composition of the present invention, when applied to cotton fabric, was shown to maintain a high sterilization power of 95% or more even after 10 washes.

As described above, the sterilizing composition of the present invention has an excellent sterilizing power of 99.9%, and when applied to the fiber, the polymer and the sterilizing powder are strongly adsorbed on the fiber and thus are not removed even after washing, thereby providing a semi-permanent sterilizing effect. By properly diluting the composition of the present invention in a sprayable form, it can be used as a spray product that can be easily applied to sterilization of fibers.

Claims (5)

Oil-in-water type polymer emulsions having a solids content of 35% to 45% by weight; And 45 to 55 parts by weight of silicon dioxide (SiO ₂ ), 8 to 12 parts by weight of aluminum oxide (Al ₂ O ₃ ), 3 to 5 parts by weight of potassium hydroxide (KOH), magnesium oxide (magnesium oxide) oxide, MgO) 3 to 5 parts by weight, boric acid (H ₃ BO ₃ ) 25 to 30 parts by weight, manganese oxide (MnO) 3 to 5 parts by weight, ferrous oxide (FeO) 2 to Sterilizing powder comprising 3 parts by weight and 2-3 parts by weight of trioxide (Red oxide, Fe ₄ O ₃ ) comprising an amount of 0.5 to 5% by weight based on the weight of the polymer emulsion, Bactericidal composition. The method according to claim 1, wherein the sterilizing powder is 1 to 400 parts by weight of silver ions, 1 to 400 parts by weight of zinc ions, 0.1 to 50 parts by weight of platinum group elements and 1 to 200 parts of polyhexamethyleneguanidine phosphate based on 100 parts by weight of the sterilization powder. A sterilizing composition further comprising at least one substance selected from the group consisting of parts by weight. The ionized solution of claim 2, wherein the platinum group element is selected from the group consisting of ruthenium (Ru), rhodium (Rh), palladium (Pd), osmium (Os), iridium (Ir) and platinum (Pt) Sterilizing composition used in the state. The sterilizing composition according to claim 1, wherein the aqueous polymer emulsion is selected from the group consisting of a polyurethane resin, an epoxy resin, an acrylic resin, a vinyl acetate resin, and an unsaturated polyester resin. The sterilizing composition according to any one of claims 1 to 4, which is diluted 5 to 10 times with water.