KR20040009978A - Inorganic ceramic antibiotics and manufacturing process - Google Patents

Abstract

PURPOSE: Provided are an inorganic ceramic antibiotics and a manufacturing process. Therefore, the manufactured inorganic antibiotics is harmless to the human body, shows stabilized bactericidal activity and antibiotic activity and absorbs harmful material as well as removes bad smell. CONSTITUTION: An inorganic ceramic antibiotics is manufactured by the steps of: mixing 82-89 wt.% of mordenite, 1-10 wt.% of tourmaline and 10 wt.% of bentonite adding the mixture to a mixed solution of AgNO3 and distilled water in a mixing ratio of 1:10; and reacting the mixture with Ag.

Description

Inorganic ceramic antibiotics and manufacturing process

The present invention relates to an inorganic ceramic antimicrobial agent and a method for manufacturing the same, and more particularly, to prepare a ceramic antimicrobial agent by reacting silver (Ag) in a silver nitrate aqueous solution in a mixture prepared by mixing the components of mordenite, tourmaline and bentonite according to a specific ratio The present invention relates to an inorganic ceramic antimicrobial agent having a stable and continuous disinfection and antimicrobial effect, deodorizing harmful substances and deodorizing odor without affecting the human body, and a method of manufacturing the same.

Recently, as consumers' interest in hygiene and cleanliness increases, it is well known that antimicrobial products are being poured out to prevent damage caused by bacteria in daily life.

Generally, antimicrobial agents are classified into organic antimicrobial agents and inorganic antimicrobial agents. Organic antimicrobial agents have high transparency and various sanitary packaging uses to suppress bacterial growth, confectionery baking and instant food packaging films, medical supplies and pharmaceutical packaging films, and long-term storage purposes. It is used in emergency food and pharmaceutical storage films, antibacterial tapes, fibers, etc. where the antibacterial activity is used and its use is also very versatile.

By the way, the organic antimicrobial agent is added to various products and has an antimicrobial effect has been rejected by consumers because of the objection of the harmfulness of the human body and the antimicrobial activity, distrust of safety, the use is very limited.

Recently, inorganic antimicrobial agents that have excellent advantages in terms of antimicrobial activity and are easy to apply to various products are mainly used. Also, there are problems of degrading product quality due to intermittent antimicrobial and bactericidal properties, unsafe safety and discoloration with time there was.

The present invention aims to solve the conventional problems as described above, and is a hydrous silicate mineral containing a small amount of cation in chemical composition, a reticulated silicate mineral in crystal structure, cation exchange, adsorption and molecular sieve, catalyst, dehydration and resorption. Mordenite with characteristics; Tourmaline, a borosilicate having a hexagonal columnar crystal and having the property of generating electricity by itself; Bentonite, which has a crystal structure with water layer and exchangeable cations, is adsorbed and has high reactivity, and is dried and calcined according to a specific ratio, and then calcined by silver {Ag} reaction in silver nitrate to form an inorganic antimicrobial agent. The present invention provides an inorganic ceramic antimicrobial agent and a method of manufacturing the same, which have a strong growth inhibitory ability and killing ability against bacteria and fungi such as Escherichia coli and Staphylococcus aureus, which are stable to the harmfulness of the human body, and which absorb harmful substances and deodorize odor.

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Hereinafter, the present invention will be described in detail.

Inorganic ceramic antimicrobial composition for safety and sustained disinfection and harmful substance adsorption and desorption to human body is composed of 82-89% by weight Mordenite, 1-10% by weight Tormaline, and 10% by weight Bentonite to form a combination of silver nitrate {AgNO ₃ } and Distilled water was mixed with a silver nitrate solution in a ratio of 1:10, characterized in that the silver {Ag} reaction.

Here, the composition ratio of the above formulation is 60-79% by weight Mordenite, 11-30% by weight Tormaline, and 10% by weight Bentonite; 40-54 wt% Mordenite, 31-50 wt% Tormaline, and 15 wt% Bentonite.

In the inorganic ceramic antimicrobial preparation according to the present invention, Mordenite, Tormaline and Bentonite are mixed in a specific ratio, mixed in a ribbon mixer for 30-60 minutes, and then the weight percent of the compound and water are added in a ribbon mixer in a ratio of 7: 3. Mixing for 30 minutes, wherein the amount of water to be mixed is gradually reduced or increased depending on the situation;

Put the blended mixture into the granulator and make the seeds about 300-1,000 per minute and take about 3 minutes to make the seeds, and when the seeds are made, sprinkle the mordenite powder without mixing the water while lowering the rotation speed of the granulator. Seed step to prevent the non-sticking to generate a size of 0.5-1mm;

Mordenite, Bentonite, and the water by weight ratio of 9: 1: 1 ratio in a ribbon mixer in the mixing for 30 minutes, wherein the amount of water to be mixed in a second or less by increasing or decreasing the amount of water depending on the situation;

Put the seeds made above into the granulator, adjust the revolutions per minute to about 100-300, spray the mixture and water mixed secondly, coat the mixture on the seed particles, and finally apply the granulator until the ball is about 6mm in size. Coating while turning;

Drying step of putting the mixture made in the form of a ball into a batch type dryer to dry at 150 ℃ for about 10 hours to completely remove the adhered moisture;

Firing the dried blend in an electric furnace at 900-1000 ° C. for about 6-10 hours to increase the surface strength;

Waiting until the temperature reaches 400 ° C. in an electric furnace and cooling at room temperature for about 24 hours;

Adding silver nitrate {AgNo3} in distilled water at a 1:10 ratio and completely dissolving the mixture, leaving the mixture in the solution for 24 hours to react with silver;

After the compound is finished the silver reaction, put into water about 1 times the volume of the compound, left for about 1 hour and then removed to remove the water and repeat this process three times to remove the unreacted silver ions;

A drying step of removing adhesion moisture by drying at 150 ° C. for 5-10 hours in a batch type dryer;

The dried blend is heated in an electric furnace at 900-1000 ° C. for about 6-10 hours to completely remove moisture and increase the surface strength.

And an Example is demonstrated by said manufacturing process as follows.

Example 1

The blending ratio is blended as in Table A and treated in the same manner as in the above production process.

Example 2

The blending ratio is blended as shown in B of Table 1 and treated in the same manner as in the above production process.

Example 3

The compounding ratio is blended as in Table 1 C and treated in the same manner as in the above production process.

Referring to the inorganic compound blended in the present invention as follows.

Mordenite is Na, K, Ca, Mg in chemical composition; Hydrous aluminosilicates, which contain small amounts of Sr or Ba as cations, are three-dimensional, with all the oxygen in the (Si, Al) O ₄ tetrahedron, one of the basic units of the silicate mineral, shared by another tetrahedron Unlike the quartz and feldspar minerals that have the same structural form, they form a lattice structure that is large enough to form large cavities of 2.3-7.5 ,, and form Si in (Si, Al) O ₄ tetrahedron. ^In order to compensate for the charge deficiency caused by the substitution of some of ⁴⁺ by Al ³⁺ , cations are introduced into the structure and are easily replaced by the cations, and the inorganic and land molecules are selectively selected depending on the size and shape of the cavity. Due to its specific crystal structure, it contains a lot of zeolite water in the mineral and low It has physical properties such as specific gravity, high whiteness and fine crystal state.

Tormaline is a borosilicate with hexagonal columnar crystals. It is a natural mineral belonging to hexagonal system, and the tourmaline crystal itself generates electricity. It has the nickname of tourmaline (電 별칭 石). At the moment, water is discharged, and water is electrolyzed, and water molecules (H ² O) are separated into hydrogen ions (H +) and hydroxyl ions (OH-), and the separated hydrogen ions (H +) are attracted to the negative electrode there. As it is combined with the emitted electrons and neutralized, it becomes hydrogen gas (H ₂ ) and evaporates so that water becomes alkali ionized to sterilize and antibacterial, and hydroxyl ion (OH-) is combined with the surrounding water molecules and hydroxyl (H _3). O ₂ ) It becomes a surface-active substance called anion and emits far infrared rays with a long wavelength of 5 μm or more to promote blood circulation and thrombolysis in the human body.

The basic crystal unit of Bantonite is silica tetrahedron and aluminum octahedral structure, which is composed of expandable three-layer plate (Si-Al-Si) structure of montmorillonite mineral system.The thickness of three-layer plate is about 10 (9.5) when wet and about 30 or more when wet. It has the property of swelling more than 3 times of plate crystal layer spacing during drying and wetting. It has good adhesiveness by mixing with other materials and expands 13-16 times of volume when reacted with water. It can be seen that bentonite exhibits recovery to its original volume when water removal or evaporation occurs.

In addition, silver {Ag} has long been known that it has antimicrobial properties, and the compound is still used in medicine and various industries, and it can be seen that it has an antimicrobial power by patent 57402 (plant growth promoting antimicrobial composition). .

In the present invention, the compound prepared according to the specific ratio of mordenite, tourmaline, and bentonite is contained in an aqueous solution of silver nitrate and reacted with silver {Ag} to be rinsed, and then calcined to prepare an inorganic ceramic antimicrobial agent. By controlling the composition ratio like B and C, it maintains continuous antimicrobial power, is harmless to human body, and has excellent whiteness. Especially, it is a powder form that is suitable for various purposes by using a feature that is excellent in adsorption and deodorization of harmful substances. A filter such as an air purifier, a water purifier, an air conditioner, a humidifier, and the like; Decorative agents such as wallpaper, carpet, and curtain; Bedding such as towels and water hangers; It can be used in various ways such as medical, sanitary, and daily necessities.In particular, by using deodorizing and releasing far infrared rays, antibacterial and harmful substances are stored in the form of grains or powder in the carrier and stored inside the refrigerator. It can be used to remove various unpleasant odors emitted from various foods.

The inorganic ceramic antimicrobial agent has a particle size of 3.5 μm or less, the particles are fine, the color is bright white, and 0.7 wt% or less of the raw materials are added.

[Experiment 1]

This experiment is to confirm the trend of bacterial changes.

1. Two test vessels were used for 24 hours shaking culture at 35 ± 0.1 ° C to increase at least 46-fold from the initial bacterial count of 1.4 × 10 ⁵ to less than 6.4 × 10 ⁵ and <10, respectively.

2. 0.1% concentration of the sample was administered here.

3. It is shown in Tables 2-1 and 2 that the bacterial reduction rate is almost completely removed to 99.9%.

[Experiment 2]

This experiment is to confirm the change of antimicrobial activity.

1. Table 3 shows the effective range of antimicrobial activity by measuring the minimum growth inhibitory concentration {MIC} and the minimum bactericidal concentration {MBC} of various harmful bacteria in order to confirm the effective species of the antimicrobial agent.

2. The test bacteria were cultured at 25 ° C. for 24 hours and then tested for antibacterial activity in plastic resin products and textile products.

3. Table 4 shows the results of improving the rate of reduction to at least 92%.

[Experiment 3]

Acute oral toxicity to the rat

The test animals were five male and female rats, and 2,000 mg of inorganic ceramic antimicrobial agent per kilogram of body weight was diluted orally administered in distilled water, and clinical symptoms were observed.

2. Skin irritation test {Skin irritation to the rabbit}

0.5 g of inorganic ceramic antimicrobial agent was attached to the skin of three rabbits, and clinical symptoms and erythema and edema of the skin were observed for 4 days.

3. In order to investigate the effects of genetic mutations in the reverse mutation test using Salmonella typhimurium, the mutagenicity was investigated with the solvent concentration group and the positive control group at the highest concentration of 5,000 µg / plate and the azeotropy of 2.

The test results are shown in Table 5.

Thus, the present invention is easy to operate by providing the product according to the required product form by composing grain or dry pulverized in the form of powder according to the purpose and purpose of firing the compound composed of mordenite, tourmaline, bentonite by silver reaction Can improve efficiency.

In addition, there is a lot of effects, such as excellent antibacterial power and can completely eliminate the distrust of the consumer safety without harm to the human body.

Claims (6)

The composition was prepared by mixing 82-89% by weight Mordenite, 1-10% by weight Tormaline, and 10% by weight Bentonite to form a blend, which was mixed with silver nitrate {AgNO ₃ } and distilled water in a ratio of 1:10 to silver nitrate solution. Inorganic ceramic antimicrobial agent The inorganic ceramic antimicrobial agent according to claim 1, wherein the composition is composed of 60-79 wt% Mordenite, 11-30 wt% Tormaline, and 10 wt% Bentonite. The inorganic ceramic antimicrobial agent according to claim 1, wherein the composition is composed of 40-54 wt% Mordenite, 31-50 wt% Tormaline, and 15 wt% Bentonite. 82-89% by weight Mordenite, 1-10% by weight Tormaline, and 10% by weight Bentonite were added to the ribbon mixer, mixed for 30 to 60 minutes, and then again the weight ratio of the compound and water was 7: 3 in the ribbon mixer. Add to the mixture for 30 minutes, and the amount of water to be mixed is gradually reduced or increased depending on the situation; Put the blended mixture into the granulator and make the seeds about 300-1,000 per minute and take about 3 minutes to make the seeds, and when the seeds are made, sprinkle the mordenite powder without mixing the water while lowering the rotation speed of the granulator. Seed step to make the size of 0.5-1mn non-stick; Mordenite, Bentonite, and the water by weight ratio of 9: 1: 1 ratio in a ribbon mixer in the mixing for 30 minutes, wherein the amount of water to be mixed in a second or less by increasing or decreasing the amount of water depending on the situation; Put the seeds made above into the granulator, adjust the revolutions per minute to about 100-300, spray the mixture and water mixed secondly, coat the mixture on the seed particles, and finally apply the granulator until the ball is about 6mm in size. Coating while turning; Drying step of putting the mixture made in the form of a ball into a batch type dryer to dry at 150 ℃ for about 10 hours to completely remove the adhered moisture; Firing the dried blend in an electric furnace at 900-1000 ° C. for about 6-10 hours to increase the surface strength; Waiting until the temperature reaches 400 ° C. in an electric furnace and cooling at room temperature for about 24 hours; Adding silver nitrate {AgNo ₃ } in distilled water at a 1:10 ratio and completely dissolving the mixture, leaving the mixture in the solution for 24 hours to react with silver; After the silver reaction is completed, the mixture is placed in water about 1 times the volume of the compound, left for about 1 hour, and then taken out to remove water, and the process is repeated three times to remove unreacted silver ions; A drying step of removing adhesion moisture by drying at 150 ° C. for 5-10 hours in a batch type dryer; Method for producing an inorganic ceramic antimicrobial agent, characterized in that consisting of a firing step of heating the dried formulation to 900-1000 ℃ about 6-10 hours in the electric furnace to completely remove the adhesion moisture and increase the surface strength 5. The method of producing an inorganic ceramic antimicrobial agent according to claim 4, wherein the blend is 60-79 wt% Mordenite, 11-30 wt% Tormaline, and 10 wt% Bentonite. 5. The method for producing an inorganic ceramic antimicrobial agent according to claim 4, wherein the blend is made of 54% by weight Mordenite, 31-50% by weight Tormaline, and 15% by weight Bentonite.