KR200372612Y1 - Bracelet With Apparutus For Blood Purification - Google Patents

Abstract

The present invention relates to a bracelet provided with a mechanism for purifying blood using natural light, wherein the blood purification apparatus is composed of a housing coupled to the bracelet strap and blood purification means coupled to the housing through a closing member, the blood The purifying means is inserted into the receiving groove of the housing, the edge is coupled to each other, and the upper and lower parts are disposed to face each other, and are disposed between the upper and lower calcite layers made of calcium carbonate and the upper and lower calcite layers to have a constant composition ratio and a predetermined thickness. It consists of a manufactured filter plate resin layer and a pressure-sensitive adhesive layer filled between the upper and lower calcite layer and the filter plate resin layer to adhere the two layers, the light transmitted through the blood purification means acts on the blood of the human body, the activity of some enzymes in the blood By improving the various indicators related to blood coagulation to a steady state, It can be used without the manipulation of the sphere, and it can be worn in general natural light, making it easy to carry and reducing manufacturing costs.

Description

Bracelet with Apparatus for Blood Purification {Bracelet With Apparutus For Blood Purification}

The present invention relates to a bracelet to be worn on the wrist, in particular, the light passing through the blood purification mechanism provided in the bracelet acts on the human body, thereby changing the activity of some enzymes in the blood to improve the pathological state of blood to a normal state The present invention relates to a bracelet provided with a blood purifying mechanism.

Bracelets that are used as accessories are habitually worn for visual aesthetic effects rather than as needed, and are very diverse in shape and form, which makes it difficult to meet their needs. Bracelets to help promote health have been conventionally manufactured.

However, in recent years, the word "well-being" has been in vogue, and interest in health care methods based on natural methods is increasing. However, conventional bracelets merely attach precious stones that are good for health. It is difficult to confirm the function of health promotion.

On the other hand, attempts to anticipate the therapeutic effect by light have been developed rapidly since the last century and to this day with the development of science and technology. There are many researches in the world of low level laser therapy (LLLT) technology and LED technology. It's going on.

However, while the positive therapeutic effects of coagulation and lipid systems and further hemodynamic changes by these techniques are evident, the mechanism of action has not yet been elucidated. In order to irradiate the light, it must be made of an electric appliance, etc. Therefore, it is inconvenient to carry at ordinary cost, and there are disadvantages such as not being able to personally use it, and there is a problem of taking time to use and receiving treatment. .

In addition, the conventional method by irradiating light of arbitrarily adjusted wavelengths, not natural light, it is inevitable to exclude the possibility of harmful effects on the human body, and social awareness of the side effects of such artificial treatment methods are also poor.

In addition, such a conventional method has a problem in that the manufacturing cost is increased due to the use of a laser semiconductor or manufacturing a device, and there is a disadvantage in that the subsequent use continues to cost.

The present invention was devised to solve the above-mentioned problems, and has an excellent decorative effect, does not cause any inconvenience to the movement of the body when worn, and makes the various indicators in the blood close to normal values due to the function of the blood purification apparatus. The purpose is to provide a bracelet with a blood purification mechanism to have a positive effect on the human body.

Another object of the present invention is to eliminate the possibility of harmful side effects by using general natural light instead of the light of a randomly manipulated wavelength, and thus a bracelet equipped with a positive blood purification apparatus in terms of social awareness. To provide.

1 is a perspective view schematically showing a state of use of the bracelet with a blood purification apparatus according to the present invention,

FIG. 2 is a cross-sectional view taken along line A-A and enlarged parts of FIG.

Figure 3 is a flow chart for product testing of the blood purification apparatus proceeded with a laser oscillator and laser power meter,

4 is a graph showing the product test results in the relationship between the boundary rotation angle and the output.

Explanation of symbols on the main parts of the drawings

10: blood purification apparatus 20: bracelet strap

110; Housing 120: finishing member

130: blood purification means 131: calcite layer

132: filter plate resin layer 133: pressure-sensitive adhesive layer

301: laser oscillator He-Ne laser 302: inspection products

303: Laser Output Meter NK-4

Bracelets provided with a blood purification mechanism of the present invention for achieving the above object is a bracelet provided with a blood purification mechanism for purifying blood using natural light in the bracelet strap worn on the wrist, the blood purification mechanism is the bracelet It comprises a housing coupled to the string and the receiving groove is formed, the blood purification means is installed in the receiving groove of the housing, and the closing member covering the housing and the blood purification means.

The blood purification means is coupled to the bracelet string and the housing is formed with a receiving groove, the edge is inserted into the receiving groove of the housing and coupled to the upper and lower portions are disposed facing each other, a pair of calcite layer made of calcium carbonate, the pair of And a pressure-sensitive adhesive layer which is filled between the calcite layer and the filtration plate resin layer and is attached between the calcite layer and the filtration plate resin layer disposed between the calcite layers.

Here, the calcite layer has a chemical composition of calcium carbonate, a specific gravity of 2.71, a refractive index of 1.49 to 1.69, a hardness of 3 or more, and a thickness deviation of not more than 10 ^-5 cm, and the degree of polishing is guaranteed as grade 4 In this condition, the light transmittance is maximized, and the optical axis is processed.

In addition, the filter plate resin layer is characterized in that it is manufactured by selecting a constant wave direction of light, covering the required wavelength band, that is, the therapeutic effect wavelength band, characterized in that it is composed of cerium which is a pigmentation inhibitor other than the glass component. do.

In addition, the pressure-sensitive adhesive layer is made of polyvinyl alcohol, the refractive index of the light is the same as the calcite layer, the refractive index and the transmittance of the light is characterized in that the same before and after curing.

In addition, it is preferable that the pressure-sensitive adhesive layer does not contain moisture.

Light passing through the blood purification apparatus provided in the bracelet of the present invention made as described above acts on the human body, thereby changing the activity of some enzymes in the blood to improve the blood in a pathological state to a normal state, in particular, cholesterol level Lower blood pressure.

Hereinafter, with reference to the accompanying drawings, preferred embodiments of the present invention will be described in detail.

1 is a perspective view schematically showing the state of use of the bracelet with a blood purification apparatus according to the present invention, the present invention is a blood purification mechanism that functions to purify the blood just by wearing on the wristband (20) ( 10) is provided, the bracelet strap 20 is generally made of metal, it can be used a variety of materials such as plastic. Blood purification apparatus 10 may be provided with one, two or more may be provided.

FIG. 2 is a cross-sectional view taken along line AA and enlarged main portion of FIG. 1, wherein the blood purification apparatus 10 includes a housing 110 coupled to the bracelet 20, and an accommodation groove formed inside the housing 110. Blood purification means 130 is inserted and coupled to the edge, and the closing member 120 covering the upper edge of the blood purification means 130.

The housing 110 may be made of metal together with the bracelet strap 20, or may be manufactured to be connected as one.

The closing member 120 located above the housing 110 and the blood purification means 130 may be made of metal, such as the housing 110 and the bracelet strap 20, while connecting the blood purification means 130 with the bracelet strap. In order to allow the light to pass through the blood purification means 130, it is produced to surround only the edge of the blood purification means 130. This serves to ensure that the blood purification means 130 is tightly coupled within the housing 110.

As shown in the enlarged view of the main part of the housing 110, the blood purification means 130 located inside the housing 110 is composed of five layers, and the upper and lower parts are disposed to face each other, and a pair of calcite layers made of calcium carbonate ( 131 and a glass filter plate resin layer 132 disposed between the pair of calcite layers, and an adhesive layer 133 filled between the calcite layer 131 and the filter plate resin layer 132 and attached thereto. Consists of including.

Here, the calcite layer 131 has a chemical composition of calcium carbonate (CaCO ₃ ), a specific gravity of 2.71, a refractive index of 1.49 to 1.69, and a maximum light transmittance under a condition of guaranteed hardness of 3 or more. It should be machined into an optical axis. The thickness deviation of the calcite layer 131 should not exceed 10 ^-5 cm, it is preferable to guarantee the degree of polishing.

The filter plate resin layer 132 is manufactured by specially selecting a wave direction of light while covering a required wavelength band, that is, a therapeutic effect wavelength band, and a glass component 95 such as silicon (SiO ₂ ) and boron (B ₂ O ₃ ). %) In addition to cerium (CeO, 5%).

The pressure-sensitive adhesive layer 133 should have the same refractive index as that of the calcite layer 131 and should be the same before and after the refractive index and transmittance of the light are cured. In addition, the adhesive layer 133 should not contain moisture.

It is preferable that the total thickness of the five layers including the calcite layer 131, the filter plate resin layer 132, and the pressure-sensitive adhesive layer 133 of the blood purification apparatus does not exceed 2.5 mm.

Figure 3 shows a flow chart for product testing of the blood purification apparatus according to the present invention with a laser oscillator and laser power meter.

3, 301 shows a laser oscillator He-Ne laser, lambda = 632 nm, oscillation output is 3 mW, 302 shows a test product, and 303 shows a laser power meter NK-4.

First, the laser oscillator is operated to pass the He-Ne laser through the inspection product to reach the receiver of the laser power meter 303.

At this time, the inspection product reads the output value displayed on the laser output meter 303 while rotating 360 °.

4 is a graph showing the product test results in the relationship between the boundary rotation angle and the output.

As shown in FIG. 4, a sin-type graph is shown indicating maximum output at the 90 ° and 270 ° positions and minimum output at the 0 ° and 360 ° positions.

At this time, if the output exceeds 0.5mW at the 0 ° and 180 ° positions, it is determined to fail.

Scientific principles

The blood coagulation system and the blood lipid system occupy an important place in the formation and completion of vascular disorders and blood circulation disorders, and are inseparably related in close association with each other.

While using a light source such as natural light or artificial light that is recognized as having no negative effect on the organism, the above-described design can be used for blood purification by an optoelectronic method in which it is distinguished from that of natural light. The scientific principle of the purification mechanism is as follows.

When the instrument is manufactured and used on the principle that light intensity is 3000 lux or more and 1J / cm ² per Kg body weight is not exceeded, the action of the third electromagnetic field of the energy density of 50mn / cm ² of blood in the blood vessel closest to the skin Changes in the activity of some enzymes in the blood under various conditions, such as catalase, plasminogen, and prothrombin, change the activity of important enzymes, such as the various indicators of the blood inclined to return to normal.

The most sensitive indicators of blood are blood circulation and coagulation, including fibrinogen, cholesterol, low-density lipoprotein cholesterol (LDL-Cholesterol), high-density lipoprotein cholesterol (HDL-Cholesterol), triglycerides, and fibrinolytic products (FDP). Important factors involved.

The results of a series of clinical trials on the therapeutic efficacy of this blood purification apparatus were conducted.

The results of clinical trials in patients with hyperlipidemia and hypercoagulation ability, which address the problem of how the blood purification apparatus affects several changes of blood coagulation and lipid indices, are as follows.

Research subjects and research methods

1) Research subject

The subjects were 58 patients and 15 normal people for 1 year from the beginning of 2002 to the end of 2002.

The age distribution of the patients was average 51 years old, and the minimum age was 40 to 73 years old (77%). The gender distribution was 62 males and 11 females. The disease distribution was thrombotic infarction patients (primary stroke) and patients diagnosed with myocardial infarction (primary myocardial infarction).

2) Research method

The blood purification apparatus was used as a portable type, and blood collection was performed two times before and after wearing the apparatus.

One experimental group was exposed to direct sunlight from the daytime 11 o'clock to 2 pm when the weather was good, maintained for 30 minutes, and then examined. The test was worn for 2 hours and 3 days after wearing. In the control group, the procedure was performed in the same manner as above without wearing the apparatus.

The indicators and the experimental methods used for each indicator are as follows.

Indicators Experiment method Solidification time Sahli-FonioLee-White Textile Stirland Law Platelet aggregation ability Born-O'Brien Fibrin breakdown products Lat method (LAT) Total cholesterol Zak-Henly High specific lipoprotein cholesterol Linwolramate Magnesium Precipitation Low specific lipoprotein cholesterol Fried Wald Triglyceride Chromotropic Colorimetric Method

Record of Research

1) solidification time

Sahli-Fonio division Contrast (n = 13) Experiment (n = 14) Average Standard Deviation Average Standard Deviation Before wearing (seconds) 465 79 211 62 After wearing (second) 433 86 492 103 Front and rear difference (second) -33 +281

※ P <0.01

n represents the number of people in the group.

As shown in Table 1, while the coagulation time was significantly increased in the experimental tank, there was no change in the control group, but rather coagulation was promoted at the mean value because the coagulation time decreased.

Lee-White division Contrast (n = 13) Experiment (n = 12) Average Standard Deviation Average Standard Deviation Before wearing (seconds) 498 85 349 80 After wearing (second) 476 81 445 101 Front and rear difference (second) -22 +96

※ P <0.05

As shown in Table 2, the solidification time in the experimental bath was significantly increased compared to the control.

2) fibrinogen

Stirland Law division Contrast (n = 13) Experiment (n = 14) Average Standard Deviation Average Standard Deviation Before wearing (mg / dl) 361.7 65.1 453.2 68.7 After wearing (mg / dl) 380.2 72.2 374.5 56.2 Front and rear difference (mg / dl) +18.2 -78.7

※ P <0.01

As shown in Table 3, the content of fibrinogen was clearly reduced in the experimental tank.

3) platelet aggregation ability

Born-O'Brien division Contrast (n = 13) Experiment (n = 14) Average Standard Deviation Average Standard Deviation Before wearing (%) 53.7 7.9 54.6 12.6 After wearing (%) 55.0 8.4 37.2 8.3 Front and rear difference (%) +1.3 -17.4

※ P <0.01

In this experiment, ADP solution was used as a material for inducing aggregation.

As shown in Table 4, there was no change in the control group, but there was a clear change in the experimental tank.

4) Fibrin Degradation Product (FDP)

Lat method (LAT) division Contrast (n = 13) Experiment (n = 12) Before wearing (µg / ml) <10 > 40 After wearing (µg / ml) <10 <10

※ P <0.05

As shown in Table 5, in the experimental tank, the FDP value was clearly lowered.

In all cases of the experimental group, the FDP value before wearing was more than 40µg / ml, but all of them dropped below 10µg / ml. .

The experiment was conducted on serum.

5) Total Cholesterol (T-CHOL)

Zak-Henly division Contrast (n = 13) Experiment (n = 14) Average Standard Deviation Average Standard Deviation Before wearing (mg / ㎗) 172.8 36.3 263.5 47.4 After wearing (mg / ㎗) 185.1 42.6 184.2 36.8 Front and rear tea (mg / dl) +12.3 -79.3

※ P <0.05

As shown in Table 6, in the experimental tank, the total cholesterol content was markedly lowered, while in the control group, the mean value was increased.

The mean experimental variation for the cholesterol standard during the experiment was C.V = 4.7% ± 0.9%, which was relatively reproducible.

6) High specific lipoprotein cholesterol (HDL-CHOL)

Linwolramate Magnesium Precipitation division Contrast (n = 12) Experiment (n = 14) Average Standard Deviation Average Standard Deviation Before wearing (mg / ㎗) 51.4 11.8 33.2 7.3 After wearing (mg / ㎗) 49.7 10.4 47.9 9.6 Front and rear tea (mg / dl) -1.7 +14.7

※ P <0.01

As shown in Table 7, the HDL-CHOL content was almost unchanged before and after wearing in the control group, but there was a clear change in the experimental tank, and increased significantly.

7) Low specific lipoprotein cholesterol (LDL-CHOL)

Fried Wald division Contrast (n = 13) Experiment (n = 14) Average Standard Deviation Average Standard Deviation Before wearing (mg / ㎗) 98.3 19.7 162.6 30.9 After wearing (mg / ㎗) 100.7 22.1 117.4 19.9 Front and rear tea (mg / dl) +2.4 -46.2

※ P <0.05

The Friedwald equation used for the LDL-CHOL calculation is as follows.

LDL-C = TC-TG / 5-HDL-C

LDL-C: Low Specific Gravity Protein Cholesterol

TC: Total Cholesterol

TG: triglyceride

HDL-C: High Specific Gravity Protein Cholesterol

As shown in Table 8, LDL-CHOL was significantly decreased in the experimental tank compared to before wearing.

8) triglyceride (T-G)

Chromotropic Colorimetric Method division Contrast (n = 13) Experiment (n = 14) Average Standard Deviation Average Standard Deviation Before wearing (mg / ㎗) 142.5 34.2 238.3 59.6 After wearing (mg / ㎗) 140.7 32.4 182.5 42.0 Front and rear tea (mg / dl) -1.8 -55.8

※ P <0.05

As shown in Table 9, triglycerides showed a clear change in the experimental tank.

Comparing experiments 5), 6), 7) and experiment 8), all the results show the same trends and clearly demonstrate the reduction of blood lipid level by the blood purification apparatus according to the present invention in various aspects.

The relationship between the blood coagulation system and the blood lipid system is closely related to each other.

Disorders in blood coagulation reflect abnormalities in the lipid metabolism system, both large and small, and lipid metabolism disorders are factors that induce and promote blood coagulation disorders.

Since then, many researchers have considered the metabolism of these two systems from a hematologic point of view in a deep connection, and there are still many unknown problems in this area.

In the above experiments, the primary focus was on the selection of subjects (samples), followed by primary cerebral thrombosis and myocardial infarction.

As the overall test results show, the clinical trial demonstrated the effectiveness of the blood purification apparatus.

As in the solidification time measurements of Table 1 and Table 2, the increased value of solidification time objectively demonstrates a decrease in fibrinogen.

Plasma fibrinogen is a determinant of blood coagulation and blood flow and has recently been recognized as a major risk factor for cardiovascular disease. Elevated plasma fibrinogen is an independent risk factor for coronary artery disease, and is a significant determinant of multivascular disease. As shown in Table 3, the results of this clinical experiment was able to see a decrease in the content of fibrinogen.

As shown in Table 5, the degradation of fibrin degradation products (FDP) is that in all the examples after the wear, the content is sharply lowered, and enters the normal stage.

Changes in blood lipids are also closely related.

As shown in Tables 6 to 9, the levels in all the lipid indicators tested were significantly lower than before and after wearing the instrument, and the relationship between the indicators varied close to physiological limits.

It is clear from our experiments that if the instrument is worn in normal daylight without the use of a special instrument, the normal target blood parameters in hyperactivity are normalized on the principle of homeostasis. Minutes already appear as a systemic effect.

Taken together, the multifunctional effects of the blood purification apparatus correlate with the basic metabolic activity of cells involved in energy formation, which in turn activates the cell's surface tension and similar fractions, while enzymatic enzymes, proteins, lipids, etc. Biological polymers and biological liquids such as plasma, lymph, blood, and moisture form photo-specific electromagnetic fields for optoelectronics, which show biological effects including biopolymerization structure changes and lead to systemicization.

According to the bracelet provided with the blood purification apparatus of the present invention as described above, it can be used to purify the blood because various indicators in the blood are deteriorated, and by using the wearing part of the bracelet as a point of health promotion, it helps to promote health. The state can improve health by using the blood purification apparatus as an accessory.

In addition, the light passing through the blood purification mechanism of the bracelet according to the present invention acts on the human body to change the activity of some enzymes in the blood to improve the blood in the pathological state to a normal state, in particular cholesterol levels and blood pressure Lowering it has a useful effect in the treatment of thrombosis, hyperlipidemia, coronary atherosclerosis, myocardial infarction and atherosclerosis.

The bracelet equipped with the blood purification apparatus of the present invention is a non-invasive therapeutic agent, which is used in the form of a favorite product that has no irritation to the wearer and is ready for everyday use, and the effect is similar when compared to the case of LLLT and LED, In particular, the cost of production is very low, and the use forms have various advantages from hospitals to homes and individuals.

Claims (4)

In the bracelet provided with a blood purifying mechanism for purifying the blood using natural light on the wristband worn on the wrist, The blood purification apparatus has a housing formed with a receiving groove coupled to the bracelet strap; And A pair of calcite layers composed of calcium carbonate disposed to face each other with an edge inserted into the receiving groove of the housing, and a glass filter plate resin layer disposed between the pair of calcite layers, and the calcite layer. And blood purification means comprising a pressure-sensitive adhesive layer is filled between the filter plate resin layer and attached thereto; And Bracelet provided with a blood purification mechanism, characterized in that it comprises a closing member covering the housing and the blood purification means. The calcite layer has a specific gravity of 2.71, a refractive index of 1.49 to 1.69, a hardness of 3 or more, and a thickness deviation of not more than 10 ^-5 cm, and the degree of polishing is processed as an optical axis as a fourth grade. Bracelet equipped with a blood purification apparatus. The method of claim 1 or 2, wherein the filter plate resin layer comprises 95% of glass components such as silicon (SiO ₂ ), boron (B ₂ O 3) and 5% of cerium (CeO) which is an anti-pigmentation agent. Bracelet is equipped with a blood purification apparatus. According to claim 3, wherein the pressure-sensitive adhesive layer is made of polyvinyl alcohol, the refractive index of the light is the same as the calcite layer, the refractive index and transmittance of the light is characterized in that before and after curing is provided with a blood purification mechanism bracelet.