KR200322689Y1 - Multichannel parallel reactor for high-throughput screening - Google Patents

Abstract

The present invention relates to a multiple parallel reactor, and more particularly, to a multiple parallel reactor capable of fast performance evaluation.

To this end, the multi-parallel reactor according to the present invention has a plurality of cartridge holders spaced apart from each other for accommodating a cartridge in which a reaction occurs, and a reaction base body through which a plurality of gas outlets communicating with a lower portion of the cartridge holder are formed, and in the cartridge holder. A plurality of corresponding gas inlets are formed therethrough, and the gas inlet includes a reactor cover coupled to an upper portion of the reaction body so as to communicate with the cartridge holder.

Description

MULTICHANNEL PARALLEL REACTOR FOR HIGH-THROUGHPUT SCREENING}

The present invention relates to a multiple parallel reactor, and more particularly, to a multiple parallel reactor capable of fast performance evaluation.

High-speed performance evaluation is a part of high-speed research technique using combinatorial technology along with high density library preparation, high density library sample synthesis and high speed characterization. Combination technology is a high-speed research technique that enables the development of new materials inexpensively, quickly and successfully by making many combination research samples at a low cost and measuring and evaluating their characteristics and performance at high speed. It consists of applied research.

In order to develop high-performance, high-efficiency new materials such as advanced functional chemical materials, a number of experiments must be conducted under various reaction conditions.

In the conventional case, since the experiment was performed in a single reactor, and the reaction conditions were to be changed every time the reaction conditions were different, there was a disadvantage in that a long time was required to find an appropriate material.

In addition, in general, a single reactor requires a pressure regulator and a mass flow controller to be installed in each line into which the reaction gas is injected, which is expensive to install, and in the case of using a plurality of reactors, each reactor is operated, controlled, and checked separately. There was a complicated downside to doing this.

In addition, since the amount of catalyst required for the conventional catalytic reactor is 100 mg or more, the minimum amount of reactant required for the experiment is not small. When a large number of experiments are required to develop a new material, not only the economic loss is large, but also the environmental damage It causes a bigger problem.

The present invention has been proposed in view of the above problems, and an object of the present invention is to provide a multi-parallel reactor capable of high speed performance evaluation.

Another object of the present invention is to provide a multi-parallel reactor capable of simultaneously evaluating catalyst performance of different compositions in a narrow space.

Another object of the present invention is to provide a multi-parallel reactor with low installation cost and easy operation.

1 is a perspective view of a multiple parallel reactor according to an embodiment of the present invention.

Figure 2 is a front sectional view of the reaction body and the reactor cover in Figure 1;

3 is a plan view of the reaction body of FIG.

Figure 4 is a plan cross-sectional view of the reaction base of Figure 1;

5 is a front sectional view of the cartridge mounted to the multi-parallel reactor of FIG.

Figure 6 is a perspective view of the insulating member is installed in the multi-parallel reactor of FIG.

7 is a perspective view of a tube, a panel and a nut connected to the gas inlet and the gas outlet in the multi-parallel reactor of FIG.

8 is a schematic rear view of a multi-parallel reactor according to an embodiment of the present invention.

9 is a state diagram used in the multi-parallel reactor of FIG.

<Description of the symbols for the main parts of the drawings>

10: reaction body 12: cartridge holder

13: hanging jaw 14: gas outlet

15: Body screw hole 16: Heater

16a: heater wire 18: temperature sensor

18a: temperature sensor wire 19: support bar

20: reactor cover 22: gas inlet

24: Cover screw hole 26: Moving bar

28: screw 30: cartridge

32: catalyst holder 34: locking end

36: thread 40: injection tube

42: discharge tube 44: panel

46: nut 48: packing

49: insulation member 50: mass flow regulator

60: check valve 70: switching valve

80: oven 82: heating section

84: fan 90: analyzer

A: catalyst

In order to achieve the above object, the multi-parallel reactor according to the present invention is a plurality of cartridge holders are formed spaced apart to accommodate the cartridge in which the reaction occurs, the reactor through which a plurality of gas outlets communicated with the lower portion of the cartridge holder A main body and a plurality of gas inlets corresponding to the cartridge holder are formed therethrough, and may include a reactor cover coupled to an upper portion of the reaction base so that the gas inlet communicates with the cartridge holder.

The cartridge holder may be arranged on a plurality of concentric circles at regular intervals.

A heater for heating the cartridge mounted on the cartridge holder may be installed between the concentric circles on which the cartridge holder is disposed, and a temperature sensor for measuring the temperature of the cartridge radially is installed between the concentric circles on which the cartridge holder is disposed. Can be. The reaction body is formed with a plurality of main body screw holes spaced apart at regular intervals on the concentric circle, the cover cover holes may be formed in the reactor cover to correspond to the main body screw holes.

A catalyst holder may be installed in the cartridge, and a catalyst may be placed in the catalyst holder.

A latching jaw may be formed at an upper end of an inner wall of the cartridge holder, and a catching end caught by the engaging jaw may be formed to protrude from the upper end of an outer surface of the cartridge. Threaded portions for easy removal can be formed.

The top surface of the cartridge may be convexly curved to maintain an airtight state, and the reaction body and the reactor cover may be further provided with an insulation member so as not to be affected by external conditions.

An injection tube and an discharge tube are respectively coupled to the gas inlet and the gas outlet, and the injection tube and the discharge tube may use a capillary tube having a smaller inner diameter than a conventional stainless tube.

One side of the injection tube and the discharge tube may be coupled to a panel (ferrule) to prevent the leakage of gas.

The injection tube may be connected to a mass flow controller for controlling the mass of the injection gas, the injection tube may be further provided with a check valve for preventing the back flow of the injection gas.

A packing for maintaining a gas tight state may be further installed between the reaction body and the reactor cover, and a switching valve for selecting a cartridge into which the reaction gas is to be injected and a cartridge to analyze the generated gas are provided in the injection tube and the discharge tube. Can be installed further.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

First, in adding reference numerals to the components of each drawing, it should be noted that the same components and the like have the same reference numerals as much as possible even if displayed on different drawings. In addition, in the following description of the present invention, if it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted.

1 is a perspective view of a multi-parallel reactor according to an embodiment of the present invention, Figure 2 is a front sectional view of the reaction body and the reactor cover in Figure 1, Figure 7 is a schematic of a multi-parallel reactor according to an embodiment of the present invention Back view.

As shown in FIG. 1, FIG. 2 or FIG. 7, the multi-parallel reactor according to an embodiment of the present invention includes a reaction base 10, a reactor cover 20, a cartridge 30, an injection tube 40, and an exhaust. It consists of a tube 42, a panel 44, a nut 46, a packing 48, a mass flow regulator 50, a check valve 60, a switching valve 70, an oven 80.

3 is a plan view of the reaction base of FIG.

As shown in FIG. 3, the reaction body 10 is a portion in which multiple parallel reactions are carried out, the cartridge holder 12, the gas outlet 14, the main body screw hole 15, the heater 16, and the temperature. It is composed of a sensor 18, a support bar 19, easy to process, such as stainless steel, made of a corrosion-resistant and inexpensive metal.

The cartridge holder 12 is a portion for accommodating the cartridge 30 in which a reaction occurs, and is disposed at a predetermined interval on a plurality of concentric circles, and a locking jaw 13 is formed. The locking jaw 13 is a portion protruding from the upper end of the inner wall of the cartridge holder 12 so that the cartridge 30 is fixed to the cartridge holder 12.

The gas outlet 14 is a portion in which the generated gas in which the reaction is completed in the cartridge 30 is discharged, and is formed to communicate with a lower portion of the cartridge holder 12.

The main body screw hole 15 is a portion formed in the reaction body 10 to connect the reaction body 10 and the reactor cover 20, and is formed at a predetermined interval on a concentric circle of the reaction body 10. It is.

The heater 16 is a means for heating the cartridge 30 mounted in the cartridge holder 12, and is disposed in the form of concentric circles between the concentric circles in which the cartridge holder 12 is disposed.

4 is a plan cross-sectional view of the reaction base of FIG. 1.

As shown in FIG. 4, the temperature sensor 18 is a means for measuring the temperature of the cartridge 30, and is radially installed between the concentric circles in which the cartridge holder 12 is disposed.

The support bar 19 is a portion for supporting the reaction base 10 installed on the bottom, and is connected to the lower portion of the reaction base 10.

The reactor cover 20 is combined with the reaction base 10 to cover the reaction base 10, and includes a gas inlet 22, a cover screw hole 24, and a moving bar 26.

The gas inlet 22 is a portion into which the gas to be reacted flows and is formed to correspond to the cartridge holder 12. The cover screw hole 24 is spaced apart at regular intervals on the concentric circle of the reactor cover 20 so as to correspond to the body screw hole 15, and the reaction body 10 and the reactor cover by screws 28. Let 20 be combined.

The moving bar 26 is a part installed on one side of the reactor cover 20 to move the reactor cover 20 up and down by a predetermined stroke with respect to the reaction base 10, an elevator such as an air compressor ( (Not shown) to move up and down.

The reaction body 10 and the reactor cover 20 were further provided with a heat insulating member 49 in order not to be affected by external conditions.

5 is a front sectional view of a cartridge mounted in the multi-parallel reactor of FIG.

As shown in FIG. 5, the cartridge 30 is a reaction part, and is composed of a catalyst holder 32, a locking end 34, and a screw part 36.

The catalyst holder 32 is a portion on which the catalyst is placed, is installed inside the cartridge 30, and uses a micro filter or frits having fine holes therein to allow gas to pass therethrough, The material may be stainless steel, pyrex glass, quartz, or the like.

In the present invention, the catalyst holder 32 is a frit of Valco Instruments Co., Ltd. (Valco Instruments Co. Inc.) having a size of 2 μm, and the catalyst holder 32 is formed of the same material as the portion to which the catalyst holder 32 is fixed. Fritz made of stainless steel was used.

The locking end 34 is a portion formed to be stepped so as to be caught by the locking step 13 at an upper end portion of the outer surface of the cartridge 30 so that the cartridge 30 is fixedly installed at the cartridge holder 12. ) Is a portion formed at the upper end of the inner wall of the cartridge 30 to easily remove the cartridge 30 from the cartridge holder 12.

In addition, the top surface of the cartridge 30 is convexly curved to maintain the airtight state by the packing 48.

Figure 6 is a perspective view of the heat insulating member is installed in the multi-parallel reactor of FIG.

As shown in FIG. 6, the reaction body 10 and the reactor cover 20 were further provided with a heat insulating member 49 such as a cowl in order not to be affected by external conditions.

7 is a perspective view of a tube and a panel connected to the gas inlet and the gas outlet in the multiple parallel reactor of FIG.

As shown in FIG. 7, the injection tube 40 is a tube connected to the gas inlet 22 of the cartridge 30 to inject the reaction gas into the cartridge 30, and the discharge tube 42. The tube 30 is a tube connected to the gas outlet 14 of the cartridge 30 in order to discharge the reaction gas generated in the cartridge 30 to the analyzer 90 or the like.

The injection tube 40 and the discharge tube 42 used a capillary tube having a smaller inner diameter than a conventional stainless tube, and the purge gas from the mass flow controller 50 is divided into 63 channels. 63 cartridges (30) at the most uniform flow rate.

The panel 44 is a device mounted between them to prevent the leakage of gas when the injection tube 40 and the discharge tube 42 are connected to the gas inlet 22 and the gas outlet 14. It is fixed by the nut 46.

The packing 48 is a means installed between them to maintain the airtight state between the reaction body 10 and the reactor cover 20, the upper surface of the cartridge holder 12 is formed convexly curved Therefore, confidentiality is well maintained.

The packing 48 used a carbon paper material to be stable within the operating temperature range from room temperature to high temperature (500 ??).

8 is a schematic rear view of a multi-parallel reactor according to an embodiment of the present invention.

As shown in Figure 8, the mass flow controller 50 is a means for adjusting the flow rate of the gas so that the reactor is injected at the correct flow rate, it is connected to the injection tube, depending on the type of the reactor Can be installed.

The check valve 60 is a means for preventing the back flow of the injection gas injected into the injection tube 40, it may be provided a plurality depending on the number of the mass flow regulator (50).

The switching valve 70 selects the cartridge 30 to inject the reaction gas from the cartridge 30 installed in the reaction body 10 or selects the cartridge 30 in which the generated gas to be analyzed is generated by ending the reaction. As a means for this, it is connected to the injection tube 40 and the discharge tube 42.

The oven 80 is a container for vaporizing the reactant when a liquid sample is used as the reactant, and includes a heating unit 82 and a fan 84.

The heating unit 82 and the fan 84 are means for raising or lowering the temperature of the oven 80 to maintain the reactants in the oven 80 in a gaseous state of constant temperature.

Hereinafter, a process of using the multi-parallel reactor according to the present invention will be described with reference to the drawings.

9 is a state diagram used in the multi-parallel reactor of FIG.

As shown in FIG. 9, the multi-parallel reactor according to the present invention lowers the movable bar 26 so that the reactor cover 20 abuts the reaction body 10, and then the main body screw hole 15. ) And the cover screw hole 24 by fastening and fixing the screw 28 to proceed with the reaction. The step is divided into a starting point in which the reactor cover 20 and the reaction base 10 are not coupled. Explain.

However, since the following steps are only examples of using the multi-parallel reactor according to the present invention, the execution order may be changed in some cases.

In the first step (S10), the injection tube 40 and the discharge tube 42 using the panel 44 and the nut 46 to prevent leakage of the reaction gas and inflow of external gas to the reaction body ( 10) and the reactor cover (20).

In operation S20, a lifting device (not shown) is operated to raise the moving bar 26 by a stroke distance.

In the third step (S30), the cartridge 30, the catalyst is installed in the cartridge holder 12 is inserted so that the locking end 34 of the cartridge 30 is caught by the locking step 13 of the cartridge holder 12 Fix it.

In the fourth step (S40), the packing 48 for airtightness is installed at the upper end of the reaction body 10.

In the fifth step (S50), the moving bar 26 is lowered by a stroke distance by a lifting device (not shown) so that the reactor cover 20 and the reaction base 10 come into contact with each other.

The sixth step (S60), by coupling the screw 28 to the cover screw hole 24 and the main body screw hole 15 so that the reactor cover 20 and the reaction base 10 is in close contact.

In operation S70, the switching valve 70 and the check valve 60 are operated so that the reaction gas is not flowed back into the cartridge 30 to be reacted.

In the eighth step S80, the temperature is sensed by the temperature sensor 18, and the reaction proceeds in the cartridge 30 heated by the heater 16.

In the ninth step S90, the cartridge 30 for analyzing the reaction result is selected by the operation of the switching valve 70, and the resultant is discharged to the analyzer 90 to analyze the result.

In the tenth step (S100), after completion of the reaction, the screw 28 is released and the reactor cover 20 is separated from the reaction body 10.

In an eleventh step S110, a screw (not shown) is fastened to the screw part 36 of the cartridge 30 to remove the cartridge 30 from the cartridge holder 12.

The above embodiments are intended to specifically illustrate the present invention, and do not limit the scope of the present invention. In addition, it can be seen that all simple modifications or changes of the present invention are included in the scope of the present invention.

According to the multi-parallel reactor according to the present invention as described above, by connecting a plurality of cartridges at the same time to react and control at the same time to provide a multi-parallel reactor capable of easy operation and high-speed performance evaluation.

In addition, according to the multi-parallel reactor according to the present invention, it is possible to analyze a plurality of catalyst materials at the same time, it is very advantageous in terms of economic and time.

In addition, the use of a small amount of catalyst on a large number of cartridges can be used several times with a small amount of catalyst, reducing the environmental problems.

In addition, the cartridge has a threaded portion inside, so that the cartridge can be easily removed from the cartridge holder after the reaction is completed, and the next experiment can be performed immediately by inserting another cartridge, so that the reactor can be easily managed and the reaction can be quickly resumed. have.

In addition, a latching jaw is formed in the cartridge holder and a catching end is formed in the cartridge so that cartridges of different lengths may be disposed in the same position of the reactor.

In addition, in the multi-parallel reactor according to the present invention, a plurality of main body screw holes and cover screw holes are formed concentrically on the reaction body and the reactor cover itself, and then fastened with screws. Will be provided.

In addition, a packing material may be installed between the reaction body and the reactor cover to maintain airtightness from being influenced by the external atmosphere. In particular, the upper end of the cartridge may be convexly curved to precisely engage the packing material so that each cartridge may be independently sealed. have.

In addition, in the present design, the capillary tube is used for the injection tube and the discharge tube. As the inner diameter of the tube decreases, the pressure difference applied to the tube increases, so that a small pressure change on the discharge side does not affect the cartridge. It is possible to eliminate the influence of the external air pressure change on the cartridge.

Claims (16)

A plurality of cartridge holders spaced apart from each other to accommodate the cartridge in which the reaction occurs, and a reaction base body through which a plurality of gas discharge ports communicating with a lower portion of the cartridge holder are formed; A plurality of gas inlet corresponding to the cartridge holder is formed through, and the gas inlet comprises a reactor cover coupled to the upper portion of the reaction body to communicate with the cartridge holder, multiple parallel reactor capable of high-speed performance. The multi-parallel reactor as claimed in claim 1, wherein the cartridge holders are arranged on a plurality of concentric circles at regular intervals. The multi-parallel reactor as claimed in claim 2, wherein a heater for heating the cartridge mounted to the cartridge holder is installed between the concentric circles in which the cartridge holder is disposed. 4. The multi-parallel reactor as claimed in claim 3, wherein a temperature sensor for measuring the temperature of the cartridge is disposed radially between the concentric circles in which the cartridge holder is disposed. The method of claim 1, wherein the reaction body is formed with a plurality of main body screw holes spaced apart at regular intervals on the concentric circle, the reactor cover is characterized in that the cover screw holes are formed to correspond to the main body screw holes, Multiple parallel reactors for performance evaluation. The multi-parallel reactor according to claim 1, wherein a catalyst holder is provided inside the cartridge, and a catalyst is placed on the catalyst holder. The water reactor of claim 1, wherein a locking jaw is formed at an upper end of an inner wall of the cartridge holder, and a locking end of the cartridge is protruded from the upper end of the cartridge holder. . The multi-parallel reactor as claimed in claim 1, wherein a screw portion is formed at an upper end of the inner wall of the cartridge to easily remove the cartridge from the cartridge holder. The multi-parallel reactor as claimed in claim 1, wherein the top surface of the cartridge is convexly curved to maintain an airtight state. The multi-parallel reactor as claimed in claim 1, wherein the reaction body and the reactor cover are further provided with an insulating member so as not to be affected by external conditions. According to claim 1, wherein the gas injection port and the gas discharge port is coupled to the injection tube and the discharge tube, respectively, characterized in that a ferrule (ferrule) for maintaining the airtight is coupled to one side of the injection tube and the discharge tube Multiple parallel reactors for high speed performance evaluation. The multi-parallel reactor as claimed in claim 11, wherein the injection tube and the discharge tube are capillary tubes having an inner diameter smaller than that of a conventional stainless tube. 12. The multi-parallel reactor according to claim 11, wherein the injection tube is connected with a mass flow controller for controlling the mass of the injection gas. 12. The multi-parallel reactor as claimed in claim 11, wherein the injection tube is further provided with a check valve for preventing backflow of the injection gas. 12. The multi-parallel reactor according to claim 11, wherein the injection tube and the discharge tube are further provided with a switching valve for selecting a cartridge into which the reaction gas is to be injected and a cartridge to analyze the generated gas. . The multi-parallel reactor capable of high speed performance evaluation according to claim 1, wherein a packing is further provided between the reaction body and the reactor cover to maintain an airtight state.