KR20030070315A - The Non-Contact Cardiovascular-Respiratory Analysis System using the 60GHz Microwave - Google Patents

The Non-Contact Cardiovascular-Respiratory Analysis System using the 60GHz Microwave Download PDF

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KR20030070315A
KR20030070315A KR1020020009796A KR20020009796A KR20030070315A KR 20030070315 A KR20030070315 A KR 20030070315A KR 1020020009796 A KR1020020009796 A KR 1020020009796A KR 20020009796 A KR20020009796 A KR 20020009796A KR 20030070315 A KR20030070315 A KR 20030070315A
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signal analyzer
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이명호
김정훈
이정환
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/0507Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  using microwaves or terahertz waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S13/00Systems using the reflection or reradiation of radio waves, e.g. radar systems; Analogous systems using reflection or reradiation of waves whose nature or wavelength is irrelevant or unspecified
    • G01S13/02Systems using reflection of radio waves, e.g. primary radar systems; Analogous systems

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Computer Networks & Wireless Communication (AREA)
  • Physiology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pulmonology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

PURPOSE: A contactless type cardiovascular-beating signal analyzer using a microwave of 60 GHz is provided to measure the beating of the heart transmitted to the outer skin by using a phase difference according to the surface vibration. CONSTITUTION: A contactless type cardiovascular-beating signal analyzer using a microwave of 60 GHz includes an oscillation unit. The oscillation unit is used for irradiating the microwave of 60 GHz to a human body. The contactless type cardiovascular-beating signal analyzer further includes a receiver. The receiver is used for receiving the microwave of 60 GHz. The contactless type cardiovascular-beating signal analyzer further includes a filter unit. The filter unit is used for removing the vibration from a surface of skin.

Description

60GHz 마이크로웨이브를 이용한 비접촉식 심혈관-호흡신호 분석 장치{The Non-Contact Cardiovascular-Respiratory Analysis System using the 60GHz Microwave}The Non-Contact Cardiovascular-Respiratory Analysis System using the 60GHz Microwave}

생명체의 생명유지에 있어서 대단히 중요한 것은 체내의 혈압을 일정하게 유지하는 것으로, 이 때문에 생명체는 여러 가지의 기구들을 겸비하고 있다. 특히 체내의 혈압을 일정하게 유지하며 각 기관ㄷㄹ에 영양분을 공급하기 위한 순환계는 생명체의 생명을 유지하기 위한 가장 중요한 수단이며 이 순환계에 가장 지배적인역할을 담당하는 신경계가 자율신경계의 교감 및 부교감신경계이다. 따라서 인체의 항상성 유지와 관련하여 인체의 외부환경에 대한 적응성, 즉 건강상태를 평가하기 위해서는 자율신경계의 분석 및 평가가 중요한 의미를 갖는다.What is very important in maintaining the life of the living thing is to keep the blood pressure in the body constant, which is why the living thing has various mechanisms. In particular, the circulatory system to maintain constant blood pressure in the body and to supply nutrients to each organ is the most important means for maintaining the life of life, and the nervous system that plays the most dominant role in the circulatory system is the sympathetic and parasympathetic nervous system of the autonomic nervous system. to be. Therefore, in order to evaluate the adaptability to the external environment of the human body, that is, the health state, in relation to the maintenance of the homeostasis of the human body, the analysis and evaluation of the autonomic nervous system has an important meaning.

인체를 대상으로 한 자율신경 활동을 검사하는 방법에는 일찍이 좋은 방법이 없었다. 일반적으로 침습적이며 시간에 따른 변화가 심하여 신뢰성이 부족하였다. 그러나 최근에 심장의 수축주기를 스펙트럼으로 해석하는 방법이 대두되고 있으며, asg은 해외문헌과 연구발표를 통하여 이 방법의 신뢰성을 높이고 있다. 심장의 수축주기, 심박수와 혈압, 또는 심박수와 호흡의 관계를 분석함으로써 자율신경계의 역할이나 활동의 숨겨진 기능들이 연구되고 있다.There was no good way to test autonomic activity in the human body. It is generally invasive and changes over time and lacks reliability. Recently, however, a method of interpreting the contraction cycle of the heart as a spectrum has emerged, and asg has increased the reliability of this method through international literature and research publications. By analyzing the heart's contraction cycle, heart rate and blood pressure, or the relationship between heart rate and respiration, hidden functions of the autonomic nervous system are being studied.

기존의 심장 신호를 측정하는 방법으로는 임피던스를 이용한 Cardiac Output 측정 장치가(도 2) 있으며, 최근에는 미국을 중심으로 해서 2GHz의 마이크로웨이브를 이용하여 비접촉식으로 심박동을 측정하는 방법이 발표되기도 하였다.Conventional cardiac signal measurement method using the impedance of the cardiac output measuring device (Fig. 2), and recently, a method of measuring the heartbeat in a non-contact method using a microwave of 2GHz in the United States has been announced.

도 2의 임피던스를 이용한 카디악 아웃풋 측정장치의 경우 심장에 가까우면서 전극의 부착이 용이한 목과 가슴둘레에 전극을 부착하여 신호를 측정하고 있다. 이방법의 문제점은 가슴 오픈상태에서의 수술이나 평소에도 옷을 벗은 상태에서 해야 하는 불편함이 있다.In the case of the cardiac output measuring apparatus using the impedance of FIG. 2, a signal is measured by attaching an electrode to a neck and chest circumference, which is easy to attach the electrode to the heart. The problem with this method is that the operation in the open state of the chest or uncomfortable to do in the naked state.

따라서 상기의 문제점을 해결하기 위하여 도 1에서와 같이 전극의 위치를 팔과 다리에 부착하였다.Therefore, in order to solve the above problem, the position of the electrode was attached to the arm and leg as shown in FIG.

또, 다른 하나의 문제는 C/O의 측정을 위하여 환자는 누운 자세에서 움직임이 없는 상태에서 신호를 측정하였으나, 환자의 연속적 모니터링이 필요한 경우 환자의 움직임에 대응할 수 있는 장치의 개발이 필요하여, 가슴에 심박동신호를 검출할 수 있는 센서를 부착하여 운동 중 심박동 수를 검출할 수 있는 소형 모니터가 개발되어 시판 중에 있다.(도 3)In addition, another problem is that the patient measured the signal in a state of no movement in the lying position to measure the C / O, but if the continuous monitoring of the patient needs to develop a device that can respond to the movement of the patient, A small monitor capable of detecting a heart rate during exercise by attaching a sensor to detect a heartbeat signal on the chest has been developed and is commercially available (FIG. 3).

하지만 상기 심박동 모니터는 심박동신호의 세밀한 요소까지는 측정하지 못하고 단지 박동 수만을 측정함으로 해서 단순히 운동선수나 스포츠동호인의 운동효과관리의 목적으로만 사용되고 있다. 국내에서는 현재 심장박동모니터에 대한 연구나 개발이 이루어진 바 없으며, 외국에서는 대형 스포츠 유통업체가 경쟁적으로 심박동모니터(Pulse Rate Monitor)를 개발하여 시판하고 있다. 하지만 이들 모두의 제품은 가슴에 신호측정부위(박동센서)를 감고 손목에 모니터를 차고 운동하는 형태로 이루어져 격한 운동에 의한 흘러내림이나 여성의 신체적 특성 때문에 발생하는 고통에 무방비인 상태이다.However, the heart rate monitor is not used to measure the detailed elements of the heart rate signal, but is only used for the purpose of managing the exercise effect of an athlete or a sports lover simply by measuring the number of beats. At present, no heart rate monitor has been researched or developed in Korea. In other countries, large sports distributors have competitively developed and marketed a heart rate monitor. However, all of these products are equipped with a signal measuring part (pulse sensor) on the chest, a monitor on the wrist, and a movement, and thus are defenseless against the pain caused by drastic exercise or the physical characteristics of a woman.

나아가 호흡신호에 대한 분석은 아직 동시에 이루어지는 않고 있다.Furthermore, the analysis of respiratory signals has not yet taken place at the same time.

본 발명에서는 기존의 부착형 전극을 사용하지 않고 인체에 무해한 파장{수mm(60㎓, λ=5mm)의 파장을 갖는 경우의 전자파는 인체의 표피부분에서 거의 전반사를 함}을 갖는 전자파를 이용한다. 공간을 이동하는 평면파가 표면에서 반사하는 특징과 표면진동에 의한 위상차를 이용하여 피검자의 심박수를 검출한다. 본 발명에 의한 비접촉식 심혈관-호흡신호 분석 장치는 외부의 표피로 전달되어지는 심장의 수축활동을 측정하기 때문에 측정센서와 표피사이에 단순한 방해막(간단한 복장)이 있어도 심장의 수축을 감지 할 수 있는 장점이 있다. 또한 연속적인 전자파를 투사하는 것이 아니라 임펄스방식으로 투사하기 때문에 검출 범위를 조정함으로써 잘못된 검출을 방지할 수 있다.In the present invention, an electromagnetic wave having a total reflection at the epidermal part of the human body uses electromagnetic waves when a wavelength of several mm (60 mm, λ = 5 mm) is harmless to the human body without using a conventional electrode. . The heart rate of the subject is detected by using the characteristics of the plane wave moving through the space reflected from the surface and the phase difference caused by the surface vibration. The non-contact cardiovascular-respiratory signal analysis device according to the present invention measures the contraction activity of the heart to be transmitted to the external epidermis, so that the contraction of the heart can be detected even if there is a simple obstruction between the sensor and the epidermis. There is an advantage. In addition, since the projection is performed by the impulse method instead of the continuous electromagnetic waves, erroneous detection can be prevented by adjusting the detection range.

비접촉식 심혈관-호흡신호 측정 장치는 전파 발송기, 노트북과 전파 발송기를 연결해주는 인터페이스 카드, 전원공급 장치, 그리고 측정, 저장된 데이터의 관리와 분석 등의 과정, 측정되는 신호를 모니터 상에 표시하는 프로그램으로 이루어져 있다. 전파발송기의 기본 작동원리는 도플러 효과(Doppler effect), 즉, 투사된 대상(즉, 인체의 가슴표면)의 미세한 위치 변경 속도 측정을 근거로 하고 있다.The contactless cardiovascular-respiratory signal measuring device consists of a radio transmitter, an interface card that connects a notebook and radio transmitter, a power supply, and a program for measuring, managing and analyzing stored data, and displaying a signal on the monitor. have. The basic operating principle of a radio transmitter is based on the Doppler effect, that is, the small displacement velocity measurement of the projected object (ie, the human breast surface).

심혈관계에서의 심장진동 근원의 주된 요인은 대동맥의 성장으로부터 혈액의 정기적인 장류인데, 이것이 외형상의 유동성 웨이브 압력을 이루게 된다. 이것이 혈관을 통해 전달되고, 이를 맥박이라 한다. 따라서 맥박은 심장과 심혈관계의 많은 구조적 기능적 요소에 관련된 활동을 반영하고, 자율신경계와 근육체계에 영향을 준다. 따라서 본 발명에 의한 측정 장치는 심장수축과 확장의 주기와 연관된 가슴의 미세한 표면진동을 원격으로 측정이 가능하여 임상적으로 많은 부분에서 그 활용성이 높다고 할 수 있다.The main source of cardiac vibration sources in the cardiovascular system is the regular intestinal flow of blood from the growth of the aorta, which results in the appearance of fluid wave pressure. It is transmitted through blood vessels and is called a pulse. The pulse thus reflects activities related to many structural and functional elements of the heart and cardiovascular system and affects the autonomic nervous system and muscle system. Therefore, the measuring device according to the present invention can be measured remotely the fine surface vibration of the chest associated with the cycle of heart contraction and expansion can be said to have high utility in many clinically.

측정의 결과는 심장활동을 반영하는 주기신호이며, 심장과 심혈관시스템에 대한 활동흐름의 평가를 컴퓨터가 자동으로 해주며, 외부 신체와 정신적 부하에 대한 자율신경계의 변화를 평가할 수 있다. 측정기는 비접촉방식으로 의복이나 구두를 착용하여도 측정이 가능하다. 이 측정기는 매우 높은 수신감도를 유지하도록 설계되었으며, 실시간으로 기록할 수 있는 능력을 가지고 있어 응급처지가 가능하다. 또한 시간적 내구성을 갖추고 측정의 재현성과 정확성이 매우 우수하다. 또한, 이측정장치는 초고주파 cross-section 영역의 무선 파장으로 작동하며 피검자에 전혀 해로운 영향을 끼치지 않는다. 본 연구에서 개발한 비접촉식 심혈관-호흡신호 측정장치의 기술제원은 다음의 표 1과 같으며, 구성도는 도 4와 도 5와 같다. 그리고 도 6은 측정장치의 외관을 나타낸다.The result of the measurement is a periodic signal that reflects cardiac activity. The computer automatically evaluates the activity flow for the heart and cardiovascular system, and can evaluate changes in the autonomic nervous system for external physical and mental loads. The measuring device can be measured even when wearing clothes or shoes in a non-contact manner. The meter is designed to maintain very high sensitivity and has the ability to record in real time, allowing first aid. It also has time durability and excellent reproducibility and accuracy of measurements. In addition, the measuring device operates at radio wavelengths in the ultra-high frequency cross-section and has no detrimental effect on the subject. The technical specifications of the non-contact cardiovascular-respiratory signal measuring device developed in this study are shown in Table 1 below, and the configuration diagrams are shown in FIGS. 4 and 5. 6 shows the appearance of the measuring device.

비접촉 심혈관-호흡신호 측정장치의 구성은 초고주파 블록, 중주파 블록, 저주파 블록, 그리고 아날로그 디지털 변환기로 구성된 Device interface 부분으로 구성된다. 최종적으로 측정된 위상차 신호는 병렬포트 연결 케이블을 통하여 노트북에 기록되고, 거기서 향후 심호의 조합과 분석이 이루어지며 측정변수와 계산변수가 그래픽과 도표형식으로 평가되며 또한 진단결과가 자동적으로 세분화되어 평가된다.The contactless cardiovascular-respiratory signal measuring device is composed of a device interface part consisting of an ultra-high frequency block, a medium frequency block, a low frequency block, and an analog-to-digital converter. Finally, the measured phase difference signal is recorded on the notebook through the parallel port connection cable, where further deep combinations and analysis are performed, the measured and calculated variables are evaluated graphically and graphically, and the diagnosis results are automatically segmented and evaluated. do.

초고주파 블록은 금속성의 단일식(monolithic)구조이며, 안테나, 기본채널과 신호채널 발진기, 초고주파 혼합기, 통풍관, 지향성 커플러(directed coupler) 그리고 도파관(wave guide)의 금속부분으로 결합된 동력분리기(power separator)로구성된다.Ultra-high frequency blocks have a metallic monolithic structure and are a power separator combined with metal parts of antennas, fundamental and signal channel oscillators, microwave mixers, air ducts, directed couplers and wave guides. separator).

중주파 블록은 기본 채널과 신호채널의 중주파수 발진기 위상검파기로 구성된다. 저주파 블록은 기본채널과 신호채널로 이루어진 아날로그식 증폭회로, 출력신호 여과기, 혼합발진기, 그리고 PC로 신호를 전달하고 향후 측정결과를 조합, 분석하는데 필수적인 아날로그-디지털 변환기로 구성되어 있다. 전류공급은 220V/110V, 60 Hz로 공급받거나 배터리를 사용할 수도 있다.The mid-frequency block consists of a medium frequency oscillator phase detector of the fundamental channel and the signal channel. The low frequency block consists of an analog amplification circuit consisting of a basic channel and a signal channel, an output signal filter, a mixed oscillator, and an analog-to-digital converter which is essential for transmitting signals to a PC and combining and analyzing future measurement results. The current supply can be supplied at 220V / 110V, 60 Hz or a battery can be used.

도 1 비접촉식 원격 모니터링용 C/O 측정기Figure 1 C / O meter for contactless remote monitoring

도 2 종래의 임피던스 C/O 측정기Figure 2 conventional impedance C / O meter

도 3 시판중인 심박동 모니터의 사용 예3 Example of use of a commercial heart rate monitor

도 4 비접촉식 심혈관-호흡신호 측정장치의 구성도4 is a block diagram of a non-contact cardiovascular-breathing signal measuring device

도 5 인터페이스 블록도 (A/D and ADSP 2105)5 Interface Block Diagram (A / D and ADSP 2105)

도 6 제작된 시스템의 외관6 the appearance of the fabricated system

도 7 비접촉식 심혈관-호흡신호 분석 장치의 구상도7 is a schematic diagram of a non-contact cardiovascular-respiratory signal analysis device

도 7은 본 발명에 의한 비접촉식 심혈관-호흡신호 분석 장치의 구상도이다. 도에서와 같이 본 발명은 임펄스 발생부 및 수신부, 반사파검출부 및 인체에 마이크로웨이브를 조사하고 수신할 수 있는 송수신기로 이루어져 있으며, 인체에서 검출된 신호를 진단 알고리즘에 적용하여 분석할 수 있도록 디지털신호처리(DSP)와 표면의 미세진동을 제거하는 필터로 구성되어 있다.7 is a schematic diagram of a non-contact cardiovascular-respiratory signal analysis device according to the present invention. As shown in the figure, the present invention consists of an impulse generator and receiver, a reflected wave detector, and a transceiver capable of irradiating and receiving microwaves on the human body, and processing the digital signal to analyze the signal detected by the human body in a diagnostic algorithm. (DSP) and filter to remove micro vibrations on the surface.

본 연구를 통하여 개발된 새로운 기술의 연구는 피검자를 통하여 얻어진 심혈관 신호의 정확도를 향상시키고 많은 종류의 성인질환의 예방의 기술적 방법들을 제공해 주는 수단이다. 측정방법으로서 전자파와 신호를 이용하는 비접촉 조사 방법은 피검자에게서 측정된 심혈관 관련 변수를 얻을 수 있으며, 이러한 방법은 매우 안전하다. 또한 이러한 방법들은 측정된 물리적 변수에 대해 높은 민감성을 보이며, 현재의 컴퓨터 기술을 사용하고 있다. 또한 실시간으로 폐조직 국부에서 일어나는 호흡주기 신호를 얻을 수 있고, 외부 호흡기능의 변수들을 산출할 수 있으며, 심장 박동에 대한 정보를 원거리에서 얻을 수 있다. 또한 이렇게 얻어진 자료를 근거로 실시간으로 원거리에서 피검자의 기능적 및 정신적 상태를 평가할 수 있다.The study of new technologies developed through this study is a means to improve the accuracy of cardiovascular signals obtained by subjects and to provide technical methods of preventing many kinds of adult diseases. Non-contact irradiation method using electromagnetic waves and signals as a measurement method can obtain the cardiovascular parameters measured in the subject, this method is very safe. These methods also exhibit high sensitivity to measured physical variables and use current computer technology. In addition, it is possible to obtain the respiratory cycle signal occurring in the local part of the lung tissue in real time, to calculate the parameters of external respiratory function, and to obtain information about the heart rate from a distance. In addition, based on the data obtained in this way, the functional and mental state of the subject can be evaluated at a distance in real time.

자율신경계의 이상이 있을 것으로 예측되는 뇌졸중, 당뇨, 척수손상 환자에서 자율신경계와 일상생활의 동작 및 하루 중의 시간적 변화(diurnal variation)와의 연관성 규명할 수 있으며, 뇌졸중, 당뇨병에서 질병의 발생, 재발 또는 예후에 대한 예측지표(predictive value)의 개발, 치료적 개입(therapeutic intervention)의 효과, 척수 손상 환자에서는 심각한 심혈관계 부작용의 예측 및 치료적 개입(therapeutic intervention) 의 유용성 규명할 수 있다.In patients with stroke, diabetes, or spinal cord injuries that are predicted to have autonomic nervous system abnormalities, the autonomic nervous system may be associated with daily behavior and daily variation in the disease. The development of predictive values for prognosis, the effects of therapeutic intervention, the prediction of serious cardiovascular adverse events and therapeutic intervention in spinal cord injury patients can be identified.

또한 효율적인 심박동과 호흡의 원격관리를 통하여 운동선수의 기초 체력훈련등에 합리적인 데이터를 마련하여 국민 체력증진에도 일조할 수 있다.In addition, through the efficient remote management of heart rate and breathing, it is possible to contribute to the national physical strength by providing reasonable data for basic fitness training of athletes.

Claims (3)

60GHz의 미세 마이크로웨이브를 인체에 조사할 수 있도록 만들어진 발진장치Oscillator designed to irradiate human body with 60 GHz fine microwave 제1항의 미세 마이크로웨이브를 수신할 수 있는 수신장치Receiving apparatus capable of receiving the fine microwave of claim 1 피부표면의 미세진동을 제거할 수 있는 필터장치Filter device that can remove fine vibrations on the skin surface
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US20140163362A1 (en) * 2012-08-01 2014-06-12 California Institute Of Technology Cardiac microwave signal determination of cardiovascular diseases
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WO2012087332A1 (en) * 2010-12-23 2012-06-28 California Institute Of Technology Systems and methods for remote long standoff biometric identification using microwave cardiac signals
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