KR20030018322A - The preparation and application method of antibacterial, deorderation used with natural extraction materials - Google Patents

Abstract

PURPOSE: Methods for preparing and applying antibacterial and deodorant microcapsule using natural extract are provided to manifest antibacterial and deodorant functions at a desired time using functions of the natural extract by forming a polymer membrane for protecting inner materials using natural chitosan when preparing the microcapsule. CONSTITUTION: The method for preparing antibacterial and deodorant microcapsule using natural extract comprises the steps of adding 0.1 to 5 wt.% of emulsifier to the solution after dissolving 2 to 20 wt.% of chitosan having a molecular weight of 50,000 into 0.5 % acetic acid to increase concentration of a polymer coating film material; dissolving carboxyl methyl chitosan in which 5 to 95% of carboxyl acid is substituted for chitosan into distilled water to form chitosan and composite; emulsifying and dispersing the mixture by agitating the mixture after adding 5 to 60 wt.% of natural extract to the chitosan solution and then adding the carboxyl methyl chitosan solution to the natural extract added chitosan solution; and microencapsulating the natural extract by continuously spray drying the solution prepared in the above step using a fluidized bed dryer.

Description

The preparation and application method of antibacterial, deorderation used with natural extraction materials}

The present invention provides a dietary supplement and a natural extract having antibacterial and deodorant properties.

By microencapsulation to control the storage stability and the timing of expression of internal substances

To maximize the effectiveness and solve the problems of deterioration that may occur during distribution.

It is about a method for a defect. In particular, the present invention is to protect the internal material

Using a natural extract of chitosan as a polymer membrane, the membrane against ammonia gas

Not only can it show selective deodorizing ability and high antibacterial ability, but it also depends on moisture.

As the wall material swells, the internal material is released to the outside and the internal material

This unique characteristic of antibacterial and deodorant can be expressed at the desired time

It would be.

Many products are released using the unique performance of natural extracts

However, due to difficulties in storage or applicability,

Is difficult. The method being used to apply these products

Furnace was applied by itself to the product, but the limitation of storage and application methods

It is not useful in itself because it causes a decrease in performance.

Many could not. More advanced methods, such as agglomeration, coating and

Introduced a method of microencapsulating the problem by physical means

It is becoming. In particular, microencapsulation is mainly used to form microcapsules.

Is a method of applying a coating material to solid particles, liquid particles in liquids or dispersions.

As a good example.

The present invention is the storage stability and antibacterial and deodorant of natural extracts

Method and application of microencapsulation technology to maximize the effect

It is about. Microencapsulation technology is an antibacterial and deodorant fabric to be encapsulated

It is natural to add lead extract as internal material and coating material as internal material.

Used by mixing the anionic polysaccharide and cationic polysaccharide

Emulsify and disperse wall materials and internal materials in a uniform size using surfactants

Spray dried to prepare powdered microcapsules containing natural substances

All.

U.S. Patent No. 5,075,114 describes coating a medicament for the purpose of masking taste.

A fluid bed method was used. In this patent,

To mask the bitter taste of oral medications, such as lofen, loperamide, and pamotidine,

Doxypropyl cellulose and cellulose acetate, cellulose acetate

The drug was coated with butyrate or mixtures thereof.

U.S. Patent 4,389,330 discloses solvents such as methylene chloride and

Together, cellulose-based as a wall-forming material to prepare a microencapsulated drug

It was presented how to.

However, when using the above methods, the coating time takes a long time,

Not only does the contamination of the drug occur with the solvent, but also the amount of residual solvent in the capsule material.

There is a disadvantage that the use is limited.

Therefore, when encapsulating natural extracts by the method used in the present invention

Not only can it shorten manufacturing time and prevent contamination by solvents,

Yield can be maximized, and the side materials of antibacterial and deodorant are used by using wall materials.

There is an advantage that can be given to the capsule function.

Natural supplements are used to extract health supplements and household goods.

In the case of manufacturing, the storage stability and product application

There is a limiting factor. In addition, the degree of polymerization of the wall material when preparing the microcapsules

If it is high or it does not dissolve in water, the effect of natural extract can be obtained in a short time.

Because of this, the effect of the internal material can be maximized at the user's desired time.

There is a need for the development of microencapsulated formulations.

Therefore, the effect of the internal material when preparing the microcapsules through the present invention

In addition, there is an advantage that the antibacterial and deodorizing function of the wall material can be obtained.

In addition, microencapsulation of natural extracts ensures stability of storage and

It is to provide a formulation that can express the inherent performance at the desired time.

The method for producing microcapsules according to the present invention includes a polymeric coating material

To increase the concentration of 2 to 40% of chitosan with a molecular weight of 35,000 to 50,000

Chitosan to dissolve in 0.5% acetic acid and then form a complex with chitosan

Carboxymethylchitosan, substituted with 5-95% carboxylic acid, was dissolved in distilled water.

Mix and add natural extract to 5-60%, emulsify and disperse by force stirring

The prepared mixed solution was polymerized at 80 ° C. for 3 hours, and then

Continuous spray drying to produce natural extract microcapsules

Microcapsules are applied to the product to produce products with improved performance.

The coating material may be a natural sugar, preferably chitosan,

Carboxymethyl Chitosan, Quaternary Ammonium Chitosan, Ethyl Cellulose, Hydroxypropyl Cell

Cellulose, methylcellulose, sodium carboxyl starch, alginate, guar gum, shantan

It can be used alone or mixed with a polymer selected as a gum, agar, starch, etc.

All.

The internal material may include a water-soluble and fat-soluble natural extract,

Water-soluble substances include green tea extract, garlic extract, ginger extract, food additives

Fat soluble substances such as flavorings, eucalyptus oil, pesticides,

Natural extract oils such as insect repellents and herbal extracts can be used.

Additives for household goods and foods by preparing the microcapsules prepared above

Can be applied as Applicable household items include sanitary napkins, diapers, soaps, radishes

It can be used by adding 0.1 to 10 parts by weight of shampoo, shampoo, body cleanser, etc.

It can be used as food additives by encapsulating food, lactic acid bacteria and the like.

1 is a block diagram for a method of manufacturing microcapsules

Figure 2 is the form of the prepared microcapsules

The present invention is a bitter taste of green tea by microencapsulating green tea extract

Not only to improve the storage stability and convenience of product application.

D. Antibacterial and deodorant functions can also be imparted. Green tea is antibacterial, deodorant and fat powder

Even though it has various functionalities such as nicotine removal ability,

Due to its peculiar bitterness and instability in distribution, its use was poor. follow

By microencapsulating green tea extract, you can mask the inherent bitter taste

By providing the stability of the pipe can not only acquire a variety of functionality,

There is also an advantage that can be extended to applications.

Hereinafter, the content of the present invention in more detail,

The present invention controls the storage stability of natural extracts and the timing of expression of internal substances.

To encapsulate the microencapsulation technology.

The natural extract we want to use as an internal material, and as a material to coat the internal material

Mix anionic polysaccharides and cationic polysaccharides extracted from nature

Combine and use wall material and inner material to make uniform size using surfactant

After emulsification and dispersion, spray drying to prepare powdered microcapsules

Consists of.

Example 1

15 parts by weight of chitosan having a molecular weight of 35,000 in 1 L three-necked flask

Dissolve and add 0.5 parts by weight of acetic acid and stir until complete dissolution.

Tween-80 is added to 2 parts by weight and completely dissolved. Green tea still life in the above solution

10 parts by weight of the agent is added and dissolved, and 2 parts by weight of carboxymethylchitosan is added.

While vigorously stirring to emulsify and disperse and react at 80 ° C for 3 hours. Manufactured

The temperature of the nozzle is 100 ℃ and the reaction solution is used at a speed of 10-15ml / min using a pump.

Microcapsules were prepared via a road spray drying process.

Example 2

10 parts by weight of chitosan having molecular weight of 50,000 parts in 1 L three-necked flask

Dissolve and add 0.5 parts by weight of acetic acid and stir until complete dissolution.

Tween-80 is added to 2 parts by weight and completely dissolved. Crude in the solution above

10 parts by weight of green tea extract was added to dissolve it, and 2 parts by weight of carboxymethylchitosan.

While stirring, it is strongly stirred to emulsify and disperse. Using the prepared emulsion liquid at the temperature of the nozzle

Through the spray drying process at 80 ° C and at a rate of 10-15ml / min using a pump

Microcapsules carrying microorganisms were prepared.

Example 3

Microcapsules were prepared according to the method prepared in Example 1,

The nonwoven fabric layer and superabsorbent polymer of lamination structure of manufactured microcapsule sanitary napkin

0.3 parts by weight of the layer was added to prepare an antibacterial and deodorant sanitary napkin

All.

Example 4

Microcapsules were prepared according to the method prepared in Example 1,

The prepared microcapsules were coated with a nonwoven fabric of diaper and super absorbent polymer.

0.3 parts by weight of the layer to effectively remove skin sores or ammonia gas

A diaper that can be removed was prepared.

The present invention is applied to the product when using the health food or household goods

It solves the problem of dissolving power or direct application and removes bad smell or taste.

In addition to antibacterial and deodorant properties, chitosan is used as a health supplement.

Method for encapsulating natural extracts.

By using chitosan, which is a natural polymer,

Because not only the effect of the material but also the effect of the polymer membrane material can be obtained.

By producing microcapsules that can impart a certain functionality,

By using the ability to express antibacterial and deodorant function at the desired time

It is about.

Claims (4)

Shielding and storing the unique aroma and bitter taste of green tea and medicine Not only to facilitate the application to the product, but also to provide antibacterial and deodorant properties. 1-55 parts by weight of natural sugar and 1-90 parts by weight of green tea extract Emulsify, disperse, spray dry and coat the surface of internal material. Prepare microcapsules and 0.001-30 parts by weight of microcapsules in household goods Method of manufacturing the product by applying. The method of claim 1, wherein the natural sugar substance is chitosan, carboxyme Tilchitosan, quaternary ammonium chitosan, ethyl cellulose, hydroxypropyl cellulose, Methyl cellulose, sodium carboxyl starch, alginate, guar gum, xanthan gum, agar, Microcapsules made by polymer alone or in combination selected from starch and the like. The method of claim 1, wherein the internal material is a crude or refined green tea powder Extracts, water soluble foods, fat soluble foods, eucharitus oil, thyme, tea tree Add 1-50 parts by weight of oil, insecticide, pest repellent, herbal extract oil, lactic acid bacteria, etc. Prepared by microencapsulation. The field for applying the microcapsules prepared in claim 1 Products of household goods such as sanitary napkins, diapers, mousse, body cleanser and cosmetics It is not limited, but manufactured using chitosan in the field of bio products and food Products that apply microcapsules.