KR200269580Y1 - Pulse wave velocity measurement system using heart sounds and pulse wave - Google Patents

Abstract

The present invention collects bio signals using a contact microphone, two electrodes for detecting ventricular depolarization wave, and a sensor capable of measuring pulse waves, calculates pulse wave propagation rate through signal processing stage, and uses the same to atherosclerosis. And a computer-based diagnostic system capable of assisting the diagnosis of various vascular diseases. The sensor of the present invention is composed of a contact microphone that can measure heart sound, two electrodes that can detect ventricular depolarization wave, and a sensor that can measure pulse wave at the location of blood vessel when the blood is ejected from the heart. . The signals detected through the sensor pass through a filter and amplification stage and are digitized and enter the computer-based analysis system. The system processes various input signals to extract variables, and measures the distance from the heart to the pulse wave measurement site. Entering it allows you to calculate the pulse propagation rate. In addition, it is possible to input the patient information, it is characterized in that it shows the waveform of the various input signals and provides a diagnostic result according to the analysis result of the input signal. It is divided into a weight system that can be placed and used in a hospital at all times and a portable system that makes it easy to diagnose patients with uncomfortable mobility, and designed to enable remote transmission for patients who want to receive medical care at home.

All.

Description

Pulse wave velocity measurement system using heart sounds and pulse wave}

The present invention relates to a pulse wave transmission rate measurement system using a heart sound and a pulse wave, and more specifically, to a heart through a microphone, an electrode capable of measuring heart sound and detecting a ventricular depolarization and a sensor capable of sensing a pulse of a pulse wave may be used. Pulse rate measurement using heart sound and pulse wave, which is useful for diagnosing and judging atherosclerosis and various vascular diseases by calculating signals and calculating pulse wave propagation rate through computer based signal collection and analysis device and diagnosing the results It's about the system.

In modern people, so-called adult diseases such as stroke, diabetes, arteriosclerosis, obesity, and heart disease have emerged as important health threats.

As age increases, blood vessels age through the process of narrowing and atherosclerosis. Atherosclerosis comes to anyone as they age and the collagen in the artery wall increases, or the elastic fibers deteriorate and the number decreases, causing the artery wall to become hard and thick.

On the other hand, atherosclerosis may be present regardless of age, and if the arterial endothelial cells are damaged due to smoking, and the function decreases, cholesterol is deposited on the vascular lining and the wall becomes thick. Blood from arteriosclerosis causes turbulence and further damages the blood vessel walls, and when blood or platelets are deposited on the wound blood vessel walls, blood clots may form, which causes direct strokes such as stroke and myocardial infarction.

Conventional methods of screening arteriosclerosis have not only been troublesome or painful for patients, but have been difficult to detect early. Therefore, vascular aging is measured more simply and indirectly, and thus effective management and treatment are urgently needed.

However, there is still insufficient research on simple and reliable measurement methods in Korea. In the current clinical trial, ECG, blood test, blood pressure, etc. may be comprehensively referred to or judged through vascular, ultrasound, and fundus tests. These tests are all related to blood vessel aging and atherosclerosis, but they are cumbersome and painful. Therefore, early detection of atherosclerosis has been difficult and it has been difficult to quantitatively determine the degree of vascular aging. In conclusion, it is time to develop a device that can accurately and easily measure and analyze blood vessel status and related diseases.

Looking at the characteristics of the pulse wave to be measured in the present invention, the pulse wave is a bio-signal that detects that the pressure wave is transmitted to the wave along the arterial wall due to the change in the aortic pressure due to the heartbeat. The pulse wave is formed by the heart and blood vessels. When the aortic internal pressure is changed by the heartbeat, the arterial wall also expands or contracts continuously. At this time, the wave propagating peripherally along the blood vessel wall is called "pulse wave".

The pulse wave propagation speed varies according to blood vessels, and it is greatly influenced by the extension of the vessel and the thickness of the vessel wall. The pulse wave velocity increases when the vessel is hard or the vessel wall is thick, and the smaller the radius of the vessel, the faster. In addition, the vascular extension decreases with age, so the pulse wave velocity is high in the elderly. In hypertensive patients, the blood vessel walls are hard, so it is difficult to stretch the blood vessels anymore, so the rate of propagation is rapid. On the contrary, veins are very extensible, so the pulse velocity is very slow, and the vein velocity is only 1 m / s. Therefore, the pulse wave velocity may well reflect the extension of the vascular system.

Looking at the conventional pulse wave detection device, a device for detecting the pulse wave according to the state of the three points on the radial artery of the patient by connecting three pulse wave detection sensors and three fixed pulse wave detection sensors that can be inserted into the finger to the signal selection circuit ( Application No. 20-1955-025696. Also, as a method of detecting pulses caused by palpation of the three fingers of the examinee from the right and left wrists of the examinee, a pulsator incorporating a plurality of pulse detection sensors has been registered in Patent 20-0201827. In addition, the pulse wave detection device (Special 1996-0007548), which detects the pulse wave caused by three levels of pressure automatically by driving three sensor rods by a stepping motor using a computer program, and analyzes the result by a computer Patented hospital pulse wave measuring device (10-0233488) that can measure the patient's blood pressure and pulse rate using the cuff and cuff drive device in contact (Special 1993-0009708) and analyze the patient's health condition based on the measured data. Registered as A medical pulse generator and pulse method for diagnosing a pulse by varying the pressure by closely contacting a diagnostic part of a pulse sensor and a terminal using a dense copper weight has been proposed in Patent 10-1999-0041048.

The pulsations applied or registered to date are characterized by measuring only pulses by attaching a pulsation sensor to a wrist or arm. However, the present invention accurately detects the point of blood ejection from the heart by using a microphone capable of listening to the heart sound, and detects the pressure pulse in the place where the carotid artery, the rhythm and the radial artery are located. In addition, it is to calculate the pulse wave propagation rate by calculating the time and distance at which the pressure pulse wave is detected in the heart, and as a result it is useful to diagnose and determine vascular diseases.

The present invention is designed to overcome the difficulty of analyzing the conventional blood vessel-related diseases as described above, it is possible to observe the activity of blood vessels using various sensors, and to measure the pulse of pulse wave where the blood vessels are located. The purpose is to analyze and diagnose the above-described vascular diseases by measuring time and distance in relation to pulse waves by attaching sensors.

1 is a schematic diagram showing the position of blood vessels in the human body.

Figure 2 is an overall configuration of the pulse wave propagation rate measurement system using the heart sound and pulse wave in accordance with the present invention.

Figure 3 is a block diagram showing the configuration of the present invention.

Figure 4 is a schematic plan view showing an enlarged first detection unit in the present invention.

5 is a schematic plan view showing an enlarged second detector in the present invention;

*** Explanation of symbols for main parts of drawing ***

10: heart rate measurement unit, 12: microphone,

14: ventricular depolarization sensor, 16: housing,

20: pulse wave measuring unit, 22: pulse wave detection sensor,

24: housing, 30: connection module,

32: preamplifier, 34: filter,

36: main amplifier, 40: computer system,

41: A / D converter, 42: digital signal processing unit,

43: display unit, 44: database unit,

45: communication interface unit,

The present invention for achieving the above object is a heart sound measurement unit attached to the chest of the body in close proximity to the heart to detect the heart sound and ventricular depolarization waveform;

A pulse wave measuring unit for detecting pressure pulse pulses such as a carotid artery, a radial artery, a finger vein, a femoral artery, and a foot artery;

A connection module for amplifying and filtering the input signal received from the heart sound measurement unit and the pulse wave measurement unit; And

It comprises a computer system for digitizing the heart sound, ventricular depolarization signal, pressure pulse wave signal to calculate the pulse wave propagation speed, and display the calculated results in numerical or waveform form.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

Figure 1 is a schematic diagram showing the position of the blood vessels of the human body, Figure 2 is an overall configuration diagram of the pulse wave transmission rate measurement system using the heart sound and pulse wave according to the present invention, Figure 3 is a block diagram showing the configuration of the present invention, 4 is a schematic plan view showing an enlarged heart sound measurement unit in the present invention, Figure 5 is a schematic plan view showing an enlarged pulse wave measurement unit in the present invention.

As shown in FIG. 2, the present invention is large,

In order to measure the pulse wave propagation rate and detect the heart sound and ventricular depolarization waveforms, the heart sound measurement unit 10 attached to the chest of the body close to the heart, the carotid artery, the radial artery, the limbic vein, the femoral artery, the femoral artery, etc. Pulse wave measuring unit 20 for detecting the pressure pulse wave pulse, the connection module 30 for amplifying and filtering the input signal received from the heart sound measuring unit 10 and the pulse wave measuring unit 20 and the sound and ventricular depolarization signal, It consists of a computer system 40 for digitizing the pressure pulse wave signal to calculate the pulse wave propagation speed and display the calculated result as a numerical value or waveform.

In particular, the heart sound measurement unit 10 of the present invention, as shown in Figures 2 and 4 constitute a contact type microphone 12 is located in the center of the housing 16 to measure the heart sound by attaching to the chest of the body It was. In addition, the ventricular depolarization sensor 14 made of an electrode for detecting ventricular depolarization waveforms at both ends of the housing centered on the microphone 12 for measuring the heart sound and at the same time to discriminate the first and second heart sounds. ).

That is, the heart sound measurement unit 10 having a single structure is designed to perform two functions in fact, and the ventricular depolarization wave is measured at the same time as the heart sound is measured, so that the accurate cardiac discharge point can be determined and determined.

In addition, the pulse wave measuring unit 20 of the present invention is flexible so that the pressure sensor 22 that can directly detect the pressure pulse pulse itself as shown in Figures 2 and 5 can be easily attached to the curved part of the body It is made of a form embedded in the housing 24 of the material.

As shown in FIG. 1, the attachment position of the heart sound measurement unit 10 that detects the heart sound and ventricular depolarization waveforms to measure the pulse wave propagation rate is the heart, and a pulse measurement unit that measures pulse waves to diagnose blood vessel related diseases ( The attachment position of 20) may be a finger vein part, a radial artery part, a carotid artery part, a femoral artery part, a foot limb artery part, or the like.

In addition to the heart sound, ventricular depolarization waveform, pulse wave in addition to the various physiological signals can be connected to the sensor when you want to measure, and installed a connection module 30 for amplifying and filtering the input signal.

As shown in FIGS. 2 and 3, the connection module 30 includes a microphone 12, a ventricular depolarization detection sensor 14, and a pressure sensor 22 of the pulse wave measuring unit 20 of the heart sound measuring unit 10. Each signal from the amplification is amplified by the preamplifier 32 having a high input impedance of the system and at the same time is responsible for the transmission of the signal to the filter unit 34 of the rear stage.

The filter unit 34 was installed to remove contact noise, muscle noise, and the like, which were input together with the input signals, and the frequency band of the heart sound filter was set to 10 Hz to 150 Hz.

The main amplifier 36 amplifies the input signal within a waveform range in which the waveforms of the signals from which the noise component is removed from the filter unit are not distorted.

Next, the computer system unit 40 of the present invention will be described.

The computer system 40 includes an A / D converter 41 for digitally converting the heart sound, ventricular depolarization signal, and pressure pulse wave signal amplified from the main amplifier.

In addition, the digital signal processor 42 may process the digital signal to display and analyze the input heart sound, ventricular depolarization signal, and pressure pulse wave signal. In this case, the first heart sound and the second heart sound may be distinguished by using the ventricular depolarization waveform. The time interval of each signal can be calculated by synchronizing the start of each signal. In addition, each measurement site is selected to measure the distance from the heart and input into the system. The pulse wave propagation speed is programmed to calculate the pulse rate through the time interval between the first heart sound, the second heart sound, and the ventricular depolarization waveform and the pressure pulse wave.

The display unit 43 displays the first heart sound, the second heart sound, and the ventricular depolarization waveform, the heart rate, and the pressure pulse waveform, and clearly shows the time intervals in which each waveform appears, and selects a section desired by the user by dragging with a mouse. As soon as the result is calculated and can be seen. Based on the carotid artery, radial artery, limbic vein, femoral artery, and femoral artery described above, an anatomical view showing the overall vascular distribution was made and the distance from the heart to the blood vessel was entered.

In addition, when the data of the patient is input to the computer system unit 40, the classification of the normal person and the abnormal person and the diagnosis information about the disease of the patient are provided based on the values of the normal person and the patient embedded in the database unit 40. To make it possible.

In addition, since the computer system 40 of the present invention is a computer-based diagnostic system, it is possible to store, output, and back up patient information and data, and to provide elderly patients and patients with discomfort who want to receive medical services at home. In order to remotely transmit data to the communication interface unit 45 may be further configured.

The present invention described above is not limited to the above-described embodiment and the accompanying drawings, and various substitutions, modifications, and changes are possible in the art without departing from the technical spirit of the present invention. It will be clear to those of ordinary knowledge.

As described above, the present invention calculates pulse wave propagation rate using heart sound, ventricular depolarization waveform, and pressure pulse wave, and thus can quantitatively and objectively diagnose and analyze vascular related diseases such as aging of blood vessels and atherosclerosis without suffering from patients. Make sure

Claims (7)

A heart sound measurement unit 10 attached to the chest of the body close to the heart using double-sided tape to detect the heart sound and the ventricular depolarization waveform; A pulse wave measuring unit 20 for detecting pressure pulse pulses such as a carotid artery, a radial artery, a finger vein, a femoral artery, a foot artery, and the like; A connection module 30 for amplifying and filtering the input signal received from the heart sound measurement unit 10 and the pulse wave measurement unit 20; And The computer system unit 40 digitizes the heart sound, ventricular depolarization signal, and pressure pulse wave signal to calculate the pulse wave propagation speed, and displays the calculated results and diagnostic information in numerical or waveform form. Pulse wave transmission speed measurement system using. The method according to claim 1, The heart sound measuring unit 10, Body contact microphone 12 located in the center of the housing 16 that can be attached to the chest of the body using a double-sided tape to measure the heart sound, and ventricular depolarization waveforms located on both sides of the microphone 12 Pulse wave transmission rate measurement system using the heart sound and pulse wave, characterized in that the ventricular depolarization detection sensor (14) consisting of electrodes to detect the. The method of claim 1, wherein the pulse wave measuring unit 20, The pressure sensor 22 which can directly detect the pressure pulse wave pulse itself is made of a form embedded in the housing 24 of a flexible material so that it can be easily attached to the curved portion of the body using a double-sided tape Pulse wave propagation velocity measurement system using heart sound and pulse wave. The method according to claim 1, The connection module 30, A preamplifier 32 for impedance matching of the signals from the heart sound measurement unit 10 and the pulsation measurement unit 20; A filter unit 34 for removing contact noise and muscle noise which are input together with the amplified signals of the preamplifier 32; Pulse wave transmission speed using the heart sound and pulse wave; consisting of a main amplifier 36 for amplifying the input signal within the waveform range of the waveform of the input signal from which the noise component is removed from the filter 34 is not distorted Measuring system. The method of claim 1, wherein the computer system unit 40, An A / D converter 41 for digitally converting the amplified heart sound, ventricular depolarization signal, and pressure pulse wave signal; Detects heart rate using digitized ventricular depolarization signal and pressure pulse wave signal, calculates time interval of signals by synchronizing the start of each signal, inputs the result of measuring distance from heart by selecting measurement area A digital signal processor 42 programmed to calculate a pulse wave propagation rate through a time interval between the heart sound, the second heart sound, and the ventricular depolarization waveform and the pressure pulse wave; Pulse wave transmission speed measurement system using the heart sound and pulse wave, characterized in that the display unit 43 for displaying the heart sound and ventricular depolarization waveform, pressure pulse waveform. The method of claim 5, wherein the computer system 40 has a database 40 is configured by using the diagnostic data for the vascular disease of the normal people and patients already embedded in the heart sound, ventricular depolarization wave, pulse wave input signals Pulse wave propagation velocity measurement system using the heart sound and pulse wave, characterized in that to provide diagnostic information for. The method according to claim 5, The computer system 40 is using the heart sound and pulse wave, characterized in that the communication interface unit 45 is further configured to operate based on the computer to store and transmit the patient's information and diagnostic results Pulse wave velocity measurement system.