KR20010025932A - Preparation method by ultrasonication of microcrystalline chitosan - Google Patents

Abstract

PURPOSE: A manufacturing process of fine crystalloid chitosan through ultrasonic treatment is provided, which is so economical method that high water retention value, various type of paste or powder, bio-degradability, bio-activity, high reactivity and chelating property are gained. CONSTITUTION: The manufacturing process is composed of: shaking chitosan powder in acetic acid solution at 20deg.C for 4 hours to get polymer solution, and removing insoluble chitosan particles by filtering the polymer solution; pyrolyzing the chitosan solution at 70deg.C for 1-3 hours by irradiating ultrasonic wave, and cooling immediately; undergoing the process of polymer coagulation of glucosamine, titrating chitosan solution with NaOH solution and controlling the pH to be 8.0 at 20±0.1deg.C while shaking at 150rpm to prepare fine crystalloid chitosan hydrogel; washing the precipitate with distilled water, drying the hydrogel at 60deg.C with a vacuum dryer or an air spray dryer; and obtaining fine crystalloid chitosan powder.

Description

{Preparation method by ultrasonication of microcrystalline chitosan}

Factors Affecting the Manufacturing Process of Microcrystalline Chitosan Economical manufacturing method through initial properties of chitosan, decomposition process, flocculation process and drying process.

The preparation of microcrystalline chitosan can be prepared by glucosamine polymer aggregation from an aqueous organic acid solution. Two types of outbreaks from solution

1) Gelatin-like properties dispersed in aqueous solution usually have a water retention valve of 500-2,000%.

2) The water retention value range of the powder is 200-800%.

New microcrystalline polymers discovered since microcrystalline cellulose are both synthesized in nature, and microcrystalline polymer production methods can be prepared by extraction by physical and chemical processes and by agglomeration or dispersion, coagulation, precipitation and crystallization of polymers from solution. Can be.

Microcrystalline chitin is prepared for the first time using hydrochloric acid designed in the microcrystalline cellulose process to remove the disordered phase by hydrolysis and degradation. In addition, the addition of phosphoric acid to the 2-propanol solution through the hydrolysis process can be produced a more effective microcrystalline chitin.

Poly-d-glucosamine is a microcrystalline form of chitin according to the temperature calculation for the N-deacetylation reaction under alkaline solution.

The process for producing microcrystalline chitosan means the regeneration of the alkaline solution, including polymer coagulation, coagulation and neutralization titration water. The properties of the product are large macromolecular structures, which differ mainly from the initial raw materials.

Microcrystalline chitosan properties depend on many factors in the manufacturing process.

Microcrystalline Chitosan Properties = (A, B, C, D)

A = initial property of chitosan, b = decomposing process factor, c = coagulation process factor, d = drying process factor

The process involves glucosamine polymer agglomeration, neutralization titration of chitoates, and precipitated hydrogels.

The preparation of microcrystalline chitosan was stirred for 4 hours at 2-4% by volume acetic acid aqueous solution of chitosan powder at 0.5-2w / w% concentration to obtain a polymer solution.

The polymer solution is filtered to remove insoluble chitosan particles.

The chitosan solution is used as an ultrasonic wave as a pyrolysis process.

Pyrolysis is performed by ultrasonic irradiation at 70 ℃ for 1-3 hours and ultrasonic 15-35 초음파. Cool immediately after pyrolysis. The preparation of microcrystalline chitosan hydrogel is titrated to pH 8.0 while stirring at 150 rpm at 20 ± 0.1 ° C. in a chitosan solution with a NaOH aqueous solution of 2.95-29.5% via glucosamine polyhedron coagulation.

The precipitated product is washed with distilled water and washed, and the hydrogel product is dried by vacuum drying or air spray dryer at 60 ° C. to obtain a microcrystalline chitosan powder.

Microcrystalline chitosan can be produced economically.

Microcrystalline Chitosan Features

-High hydrogen bonding capacity

-High intrinsic surface

-High conservative value

Distributed safety

-95% crystallinity index in solid form

-Gel-like pastes and powders in various forms

-Biodegradable

-Lifeliness

-Film forming ability directly

High reactivity, chelate properties

Claims (1)

Microcrystalline Chitosan Production Method by Ultrasonication