KR20010017969A - paste for removing tartar, containing organic acids - Google Patents

Abstract

PURPOSE: Provided is a paste or a gum including organic acids for removing tartar and plaque formed on tooth, which removes tartar and plaque easily without giving a pain to patient. CONSTITUTION: A gum for removing tartar and plaque is composed of 60-80 % by weight of gum base, 1-2 % by weight of softening agent, 8-13 % by weight of organic acid, 0.1-15 % by weight of wetting agent, and 0.1-1% by weight of perfume. A pastes for removing tartar and plaque is composed of 25-35 % by weight of paste base, 10-30 %by weight of organic acid, 30-40 % by weight of wetting agent, 0.1-1 %by weight of sweetening agent, 0.1-2 % by weight of foaming agent, 0.1-1%by weight of perfume and distilled water.

Description

Paste for removing tartar containing organic acids

The present invention relates to a paste containing an organic acid for removing plaque and tartar formed on teeth.

The tooth consists of a crown and a root portion, which is a raised part of a 2mm thick enamel solid material that appears white and serves to protect the teeth from external temperature changes or pressure when chewing food. In addition, the root portion is embedded in the alveolar bone and piled up as gingival to prevent the penetration of bacteria.

If you don't brush or clean your mouth after eating, you can get plaque or tartar on your teeth, which can lead to tooth decay, which can lead to tooth decay.

Plaque is a milky white, soft organic substance that forms on the surface of teeth after eating or on artificial surfaces such as dentures and fillings. It is composed of about 80 moisture and about 20 organic components. Organic components are mostly bacteria and contain substances produced by bacteria and solids in saliva. The plaque is formed by adhesion of a saliva-derived adhesive substance to the tooth surface to form a coating, which is attached to and proliferates bacteria existing in the oral cavity. In other words, plaque is formed by streptococci in the oral cavity attached to and propagated to adhesive materials such as dextrin and levan produced from sucrose.

Tartar is a hard substance deposited on the surface of teeth and dentures, and is formed by depositing inorganic salts in serum or saliva and calcifying plaque. Early tartar is soft, but if left for a long time without removing it, the mineral content increases and hardens. Tartar, along with plaque, causes plaque, periodontitis, and tooth decay and further causes tooth loss. Tartar is composed of mineral, organic matter, moisture, etc. The mineral contains calcium phosphate 76, calcium carbonate 3 and magnesium phosphate 4, and the organic matter contains protein 8 and fat 3.

In addition, the growth of bacteria in plaque and tartar causes dental caries. The path is as follows. Plaque is formed by food waste, and food waste penetrates into the formed plaque to produce organic acids (CH ₃ COOH or CH ₃ CH (OH) COOH) by carbohydrate fermentation, which leads to demineralization of teeth from the teeth. Calcium is eluted, causing hard tissue to collapse, resulting in caries.

Tooth decay is caused by the following mechanisms:

_{Ca 5 (PO 4) 3 OH} (s) ↔ 5Ca 2+ + 3PO 4 3- + OH -

Hydroxyapatite, the enamel layer of teeth, is a calcium phosphate that is hardly soluble in water (0.0025g / H ₂ O 100g, 25 ℃), and filling is prevented by the body's natural reverse reaction. In this reaction, corrosion is promoted as the OH ⁻ is lowered by the acid produced by the bacterial activity. Once the enamel weakens, tooth decay begins. In particular, children should be careful because the production of caries is faster than adults.

On the other hand, plaque and tartar cause periodontal diseases such as periodontitis. Periodontitis is an inflammatory reaction around the teeth caused by anaerobic bacteria that develops from gingivitis. Periodontitis destroys the collagen that supports the periodontal membrane. As the alveolar bone is dissolved and absorbed, the periodontal ligaments are separated and periodontal sacs are formed. In severe cases, the tooth is missing. Most of the pathogens that cause periodontitis are Gram-negative bacteria, which are anaerobic bacteria, which secrete collagenase to destroy connective tissue and ligaments of the root canal, and secreted toxins cause periodontitis.

Since plaque and tartar as described above are not completely removed by brushing, they should be removed by mechanical methods such as scaling. Periodontitis should be treated with a drug that inhibits gram anaerobic bacteria causing periodontitis, in addition to physical methods by scaling, or by drug use or injection.

However, treatment of plaque, plaque and injection of periodontitis by scaling not only causes significant pain in the patient, but also suffers from toothache for a certain period after the procedure. In addition, drug treatment of periodontitis may cause side effects caused by antibiotics, and drug resistance may develop.

The present inventors have completed the present invention by finding that the main components of tartar are phosphates and carbonates, and they are well soluble in acid.

An object of the present invention is to maintain a healthy mouth by dissolving plaque and calcified calculus, which are hard to be wiped out by brushing, using an organic acid-containing gum or paste.

In another aspect, the present invention aims to treat periodontitis using a gum or paste containing oral periodontitis treatment.

1 is a drawing substitute photograph showing a state wearing a tray coated with a paste according to the present invention

Figure 2 is a drawing substitute photo showing a state before wearing the tray

3 is a drawing substitute photograph showing the first wearing the tray

Figure 4 is a substitute picture showing the second wearing the tray

The present invention provides a tartar removal gum containing 60 to 80 weights of gum bases, 1 to 2 weights of softeners, 8 to 13 weights of organic acids, 0.1 to 15 weights of wetting agents and 0.1 to 1 weight of fragrances.

The present invention also contains 30 to 40 weight of wetting agent, 10 to 30 weight of organic acid, 1 to 2 weight of binder, 0.1 to 1 weight of sweetener, 0.1 to 2 weight of foaming agent, 0.1 to 1 weight of perfume, 25 to 35 weight of base and residual purified water Provide a tartar paste.

In another aspect, the present invention provides a gum or paste for removing dental plaque containing a caries preventive or periodontitis treatment.

The tartar removal paste or black organic acid according to the present invention is to prolong the contact time between the organic acid and the tartar generated in the tooth. That is, the organic acid may be applied directly to the teeth, but it is not effective to remove calculus because the organic acid is diluted by the ingested food and saliva. Therefore, the present invention is to uniformly attach the gum containing the organic acid to the teeth or to apply a thin paste so that the organic acid is gradually released from them so that the organic acid and calculus are continuously contacted for a considerable time to effectively dissolve the tartar.

In addition, in order to facilitate contact between organic acids and tartar, the paste according to the present invention may be thinly applied to the inside of a tray, which is a dental tool, and then fixed to the tooth.

As the softener used in the tartar removal gum, waxes and fats and oils can be used, and it contains 1-2 weights based on the whole gum composition.

Organic acids, which are essential components used in tartar removal gums, include citric acid, acetic acid, tartaric acid, lactic acid, malic acid, malonic acid, and the like, and contain 8 to 13 weights based on the total composition. Especially among citric acid, citric acid contained in a large amount of plum used for medicines such as chronic fatigue, muscle hardening, arteriosclerosis, diabetes, hypertension, obesity, neuralgia, acid constitution is most preferred. Strong acids, on the other hand, can be removed by completely dissolving tartar, but they are not suitable because they damage not only tartar but also teeth and skin.

When the organic acid is applied to the gum, it is preferable to contain a smaller amount than when applied to the paste. In order to remove tartar using a gum containing an organic acid, the gum is first chewed and softened, and then attached to the tooth. If the organic acid is contained in a large amount, the acidity is too strong to chew, which is not preferable.

The humectant may contain 0.1-15 wt% based on the total gum composition, and 70 sorbitol or glycerol may be used.

On the other hand, the binder used in the tartar removal paste includes carboxymethyl cellulose, hydroxyethyl cellulose, alginate salt, carrageenan, polyvinyl alcohol, and the like, and the content is 1 to 2 weights based on the whole paste composition.

Wetting agents used in tartar pastes are the same as those used in gums. The content is 30 to 40 weight based on the whole paste composition.

As the sweetener used in the tartar removal paste, sodium saccharin, stevioside, aspartame, sorbitol, licorice acid, acesulfame, and the like are used, and the content is 0.1 to 1 weight based on the whole paste composition.

As the foaming agent, sodium lauryl sulfate, sodium dodecylbenzenesulfonate, sodium laurylsulfoacetic acid, sodium lauroylsalcosinate, acyl glutamic acid, and sugar fatty acid esters can be used. It is weight.

As an essential component, the organic acid is 10 to 30 weight based on the entire paste composition, and like citric acid, citric acid, acetic acid, lactic acid, tartaric acid, malic acid or malonic acid may be used. If it exceeds 30 weights, acidity becomes strong, which is undesirable for teeth.

In the tartar removal paste, when the caries preventive agent is added, 25 to 35 weight of calcium carbonate, magnesium carbonate or calcium phosphate is added as a base.

The fragrance used in the tartar removal gum and paste may contain 0.1 to 1 weight based on the whole composition, and may use mint, strawberry, banana, and the like.

Acids may also contain tooth decay agents for the prevention and prevention of tooth decay by acid, as they cause tooth decay when in contact with teeth. The caries preventive agent is preferably 0.1 to 1 weight based on the whole composition. Examples of caries preventive agents that can be used include sodium fluoride, stannous fluoride, water soluble monophosphate, water soluble diphosphate and the like.

The present invention may also contain 2 to 10 weight of the drug for the treatment of periodontitis. The drug includes tetracycline hydrochloride, tetracycline base, minocycline hydrochloride, ibuprofen and flubiprofen.

When the paste according to the present invention is applied to a tray, the amount thereof is appropriately 0.1 to 0.5 g. More than 0.5 g is undesirable because the paste will stick out between the teeth and the tray.

If only paste or gum according to the present invention is applied or adhered to the teeth, calculus can be removed several times. However, if the paste is applied to a tray, calculus can be removed if used 2-3 times.

If you use a paste-coated tray, you can get rid of calculus considerably after only one use for about five days.

1 is a photograph showing a state of wearing a tray coated with paste, and FIG. 2 is a photograph before wearing a tray. 3 shows that the tartar has been significantly removed in the photograph after wearing the tray for 5 days. In addition, Figure 4 shows the second case, it can be seen that the tartar has been significantly removed.

If the tray is used after scaling, the calculus can be completely removed even with a wearing period of 1 to 2 days.

Hereinafter, an Example is given and this invention is demonstrated in detail.

(Example)

(Paste manufacturing)

After dissolving 5.0 g of carboxymethyl cellulose in 200 g of 70 sorbitol, purified water was added thereto, followed by complete dissolution while mixing in a water bath. 2.5 g of sodium saccharin and 5.0 g of fragrance were added to the solution, followed by sufficient mixing.

A mixture of 100 g of citric acid, 10.0 g of sodium lauryl sulfate, 0.5 g of sodium fluoride, and 150 g of sodium carbonate was added to the solution obtained above, followed by stirring.

(The manufacturing)

78.0 g of gum base and 2.0 g of softener were completely dissolved in a 60 DEG C water bath to prepare a liquid phase. 0.1 g of sodium fluoride and 9.5 g of sodium carbonate were evenly mixed with 10.4 g of fine citric acid powder, which was then dispersed in 15 g of sorbitol. This is kneaded evenly while slowly adding to the liquid phase taken out of the water bath.

(Calculus dissolution rate measurement experiment)

To determine if organic acid is effective in removing tartar, the dissolution rate of toothpaste, mouthwash, organic acid and alkali metal salt in tartar was compared.

Tartar was collected and used in various dental offices, but the calculus collected was not constant, so different calculus was used for each reagent. The collected calculus was dried in a drying oven at 100 ° C. for 1 hour. Toothpaste, gagrin, chitosan, acetic acid, citric acid and alkali metal salts were taken 1.5 g each, and they were dissolved in 30 ml of distilled water, respectively. Plaque was added to each reagent solution and washed by shaking on a shaker at 100 rpm for 20 minutes at 37 ° C. Since the calculus was taken out and dried in a drying oven at 100 ℃ constant temperature for 1 hour and the mass was measured. The results are shown in Table 1.

0 hours 3 hours 9 hours 24 hours Dissolution rate () Average Dissolution Rate () toothpaste 1 time 22.4 21.8 21.4 21.3 4.91 6.33 Episode 2 28.1 27.6 26.6 26.4 6.05 3rd time 32.4 31.5 30.1 29.8 8.02 Gagreen 1 time 46.2 45.6 44.9 44.7 3.25 3.16 Episode 2 38.4 37.9 37.2 37.1 3.39 3rd time 24.7 24.4 24.1 24.0 2.83 Chitosan 1 time 18.3 17.6 16.8 16.5 9.84 10.88 Episode 2 22.4 21.5 20.2 19.8 11.61 3rd time 23.2 22.3 21.0 20.6 11.21 Acetic acid 1 time 26.7 20.5 10.9 5.7 78.65 77.38 Episode 2 34.0 27.8 13.9 7.8 77.06 3rd time 38.2 30.4 15.9 9.0 76.44 Citric acid 1 time 26.2 20.2 10.6 5.6 78.63 80.57 Episode 2 27.4 21.6 9.2 4.9 82.12 3rd time 43.1 34.7 18.2 8.2 80.97 Sulfuric acid 1 time 39.2 Melted and crushed 100.00 Sodium bicarbonate 1 time 33.4 31.7 30.3 29.5 11.68 13.65 Episode 2 35.2 33.4 30.9 29.9 15.06 3rd time 44.3 42.2 39.2 38.0 14.22

Tartar is mainly soluble in acid because phosphate and carbonate are the main components. From Table 1, it can be seen that acetic acid and citric acid have excellent calculus dissolution rate. Sulfuric acid dissolves tartar completely, but it is undesirable because it is harmful to the human body.

The present invention has the advantage of being able to remove the pain of the patient by a mechanical method such as scale by removing the tartar mainly composed of phosphates and carbonates using an organic acid, and the procedure is easy.

Claims (5)

Tartar removal paste containing organic acid. The tartar removal paste according to claim 1, wherein the organic acid is one selected from the group consisting of citric acid, acetic acid, tartaric acid, lactic acid, malic acid and malonic acid. The tartar removal paste according to claim 1, further comprising a caries prevention agent selected from the group consisting of sodium fluoride, stannous fluoride, water soluble monophosphate and water soluble diphosphate. The tartar removal paste according to claim 1, further comprising a periodontitis treatment agent selected from the group consisting of tetracycline hydrochloride, tetracycline base, minocycline hydrochloride, ibuprofen and flubiprofen. Tartar removal gum containing organic acid.