KR20000062363A - Container having two or more compartments - Google Patents

Abstract

The container 10 for storing the two components separately and mixing them prior to use may include a housing 12 having an opening 14 and a neck portion 16, a displacement member 20 and a closure member 48. Include. The housing 12 is formed to have a first compartment 18 and a second compartment 38 communicating with each other at the neck portion. The displacement member 20 is formed such that the partition wall 22 moves from the non-sealed position where the first compartment 18 and the second compartment 38 communicate with each other to a sealed position where the neck portion 16 is sealed. Displacement member 20 has one or more conduits for introducing components through the opening into the housing. The closure member 48 seals the conduit of the displacement member and the opening of the housing 12. The displacement member 20 can be moved by rotational and traction movements and can be moved by an outer portion of the housing 12. The seal formed by the partition wall 22 of the displacement member 20 can be reshaped. That is, it can be resealed. The pre-packed, disposable, two-compartment container 10 according to an embodiment of the present invention may be remolded with a closure member 12 that cannot be removed after the closure member is removed or made of a material or method that is only allowed for single use. It has a seal that cannot be sealed and a closure member 48 that cannot be closed. The two-compartment container 10 may also include a dosing assembly for dispensing a set amount of the mixed formulation.

Description

CONTAINER HAVING TWO OR MORE COMPARTMENTS}

It is stored in dry particulate matter (powder) for various uses for humans and mixed with the liquid just before use to make up the net solution or dispersant. This is the case with various nutritional prescriptions, including breast milk substitutes (infant prescriptions), adult dietary prescriptions such as dietary powders and various medications such as antibiotics. The shelf life of this mixed prescription is limited, indicating that it is necessary to prepare the preparation only immediately before use. Since the activity of the active ingredient in the composition is also lost, for example, once the active ingredient is mixed with the liquid, oxidation and hydrolysis are accelerated and the activity is lost, thus limiting the shelf life of the mixed formulation. In many cases, mixed preparations are also susceptible to microbial contamination.

For example, when applied in various formulations, including antibiotics and antibiotics for newborns, the exact amount (weight and volume) of dry particulate matter is mixed with the correct amount (weight and volume) of liquid when preparing a synthetic formulation. It is important. Large or small quantities of the required ingredients change their proportions and change the final formulation, but within an approximation error to have an adequate effect. For example, in infant formulas, mixed liquid preparations may become thin if they are not dry enough, and children may become malnourished in this case, and mixed liquid preparations may be too concentrated in too dry preparations. Congestion may cause digestive problems and vomiting.

Under hygienic conditions and sterile conditions, the two compartments need to be filled, stored and mixed and the two compartments will be properly sterilized and of appropriate quality.

Pediatric prescription preparations in homes and clinics provide washed and sterilized bottles and nipples, and measure a large amount of powdered (dry particles) material from the canister to add a moderately measured amount of water (usually tap water), salt solution or milk Place in washed and sterilized bottles. This nipple is then attached and the two components are stirred to make a mixed liquid formulation. Large amounts of drugs, for example antibiotics, are formulated in a similar manner by pharmaceutical practitioners or end users.

The formulations prepared by mixing the two components have a short shelf life, or where the quantity, quality or sterility of the components is considered important in the formulation preparation, until the mixed formulation is dispensed. A single container capable of storing the components separately allows the two components to be mixed within the container and allows the mixed formulation to be dispensed from the container. In this case, the container is preferably packaged in advance, preferably used for one-time use by the end user, and it is desirable that the container cannot be used after one use. This storage and dispensing container provides end users with convenience, stability and cost savings.

First, the prepackaged two-compartment storage and dispensing container is convenient because it has two components of the mixed formulation, which are supplied quantitatively so that one-time use of the container always ready to be mixed is readily available. In this way, a traveler can travel with the desired number of pre-packaged containers and do not have to weigh two or more components, without having to worry about losing one of the components of the preparation while traveling. Preparations can be mixed. Pre-packaged containers filled and packaged under appropriate conditions, individually stored for easy mixing, and adjustable to allow mixing and dispensing of the final composition provide the end user with a complete system.

Second, disposable two-compartment storage and dispensing containers are packaged in a manufacturing plant where the sterilization of the environment and the sterilization of each component and mixing vessel can be controlled to provide stability. And, if previously packaged in a disposable container at the manufacturing facility, the amount of each of the two individual components can be controlled by precise metering.

Containers are known which have two sections which are mixed together prior to use, i.e. a separate section for storing liquid and dry particulate matter. This two-compartment container has a destructible and movable partition between two compartments. This bulkhead is broken or displaced for mixing.

A problem with the known two-compartment container structure is that the process of assembling, filling and packing is complicated. This is complicated by the need to assemble internal bulkheads, which have limited access to the container openings and are designed to be fragile or easily displaceable. There is therefore a need for a two-compartment container that can be easily fabricated, can simplify the assembly, filling and packaging process and provides easy and reliable operation.

The present invention relates to a container having two compartments and in particular a disposable two-compartment container, each compartment holding a separate component, for example a liquid or solid component, which is mixed with each other by the end user prior to use.

1 is a perspective view of an infant bottle according to an embodiment of the present invention;

2 is a perspective view of the infant bottle shown in FIG. 1 with the cover removed;

3 is a cross-sectional view of an infant feeding bottle in a storage position with two separately stored formula components and with a lid cap;

4a to 4e illustrate a process of filling two components, a liquid component and a powder preparation stored separately in an infant bottle according to the present invention;

5A and 5B illustrate the process of preparing the infant bottle shown in FIG. 4 for feeding;

6 is a side view of a container having two compartments in which the displacement member is completely enclosed;

7 is a side view of the container with the two compartments shown in FIG. 6 with the displacement member partially unrolled;

8 is a perspective view of the displacement member shown in FIG. 6;

9A to 9C illustrate a process of filling a medical container according to an embodiment of the present invention;

10A-10B illustrate the process of preparing a formulation stored in the container shown in FIG. 9 for dispensing;

11A-11F illustrate a process for preparing a formulation for dispensing in a medical container in accordance with another embodiment of the present invention, including a formulation taking device;

12A-12E illustrate the process of preparing for dispensing a pharmaceutical stored in a container according to another embodiment of the present invention, having another dosage device;

13A is a side view of a bottle according to another embodiment of the present invention;

13B and 13C are longitudinal cross-sectional views of the bottle shown in FIG. 13A, where FIG. 13B shows a state in which the partitions seal the two compartments, and FIG. 13C shows a state where the partitions are arranged to flow between the two compartments;

Figure 14 is a longitudinal cross-sectional view of the infant bottle body according to another embodiment of the present invention, Figure 14a shows a state in which the two compartments are sealed to each other, Figure 14b shows a state in which the partition wall to move between the two compartments 14C is an exploded view of the container of FIGS. 14A and 14B;

15 is a longitudinal sectional view of a container consisting of two compartments of a baby bottle according to an embodiment of the present invention;

16A-16F illustrate the process of mixing the two components to form a preparation before breaking and using the partition between compartments after filling the infant bottle shown in FIG. 15 to store different components of the preparation in each compartment;

17 is a longitudinal sectional view of an infant bottle according to another embodiment of the present invention; And

FIG. 18 shows the infant bottle shown in FIG. 17 when the two components are mixed to prepare the final formulation and prepare for use. FIG.

It is an object of the present invention to provide a new container having at least two compartments for storing at least two components which must be mixed before use, wherein one of the aforementioned components is a liquid and the other is a solid particle. For example a powder material. Another object of the present invention is to provide a storage and dispensing container having two or more sections which can be easily assembled and filled with two or more components. Another object of the present invention is to provide a storage container having two or more compartments that can be assembled and filled in a sterile state, which is not damaged by the preparation and dispensing of the mixed formulation. The present invention provides a container having two or more compartments for storing two or more components that must be mixed before use, which dispenses the final formulation formed by mixing the two or more components.

The present invention provides a container having two or more compartments for storing two or more components separately until mixing, for easily mixing the two or more components, and for dispensing the mixed formulation. The present invention provides a container having two or more compartments that can be operated externally to mix two or more individually stored components easily and reliably by an inexperienced end user. It is an object of the present invention to provide a complete system through a vessel having two or more sections filled with each individual component of the quantification to provide the optimum blend formulation. The present invention provides two or more disposable compartment containers for storing two or more components to be mixed prior to use, which disperse the final formulation formed by mixing the two or more components and are no longer reused.

A container according to a first embodiment of the invention is:

A housing having a dispensing opening, a lower end and a neck portion between the opening and the lower end; And

Consisting of a displacement member disposed within the housing having a partition suitable for forming a seal to prevent fluid from leaking in the neck portion to define two compartments separated by a portion of the partition,

The displacement member may move axially between two positions along an axis extending through the neck portion, the two positions flowing between the two compartments and a first position where the fluid-sealed portion is formed in the neck portion; So that the partition wall is separated from the neck portion.

The neck portion divides the vessel into two compartments, one spaced apart from the opening defining the first compartment, the other adjacent the opening defining the second compartment, and the two compartments of the compartment when in the first position. By sharing a part, they are separated from each other. The neck portion will be formed as a limited portion with a smaller cross section compared to the adjacent area of the housing. According to another embodiment of the present invention, the neck portion will be formed by a radial wall that projects inwardly of the circle.

In a first embodiment of the invention the housing is cylindrical, the neck portion has a circular cross section and the partition wall is circular. In an embodiment according to the invention the edge of the partition wall is made to form a neck portion and a sealed portion that is free of liquid leakage. It is a cooperative, elastic part forming part of the edge and an elastic member integrated at the edge, for example an O-ring fitted with a circular groove formed at the edge, one in the bulkhead and the other in the neck part, respectively. It will be achieved by a male and female matching member. The seal formed may be reformable, i.e., sealed again.

The partition wall protrudes from the operation part of the displacement member, which can be operated to allow the user to control displacement. The operating part is outside of the housing and is easily accessible and operable by the end user. In an embodiment of the invention, the septum protrudes from the steering portion but is connected at one end of one or more stems. In the case of a single stem it is central and in the case of multiple stems it is usually arranged around. In another embodiment of the present invention, the partition and the steering portion may be connected by a circumferential wall formed with an opening. In another embodiment, the partition wall and the steering portion are connected by the radial wall. This maneuvering part of the displacement member is, according to an embodiment of the invention, adapted to be screwed with the housing so that axial displacement is achieved by relative forward motion in accordance with the helical displacement during rotation. In this case the seal formed by the partition wall is controlled by the rotation of the threaded displacement member. According to another embodiment of the present invention, the displacement member is axially moved by engaging or engaging the housing and pulling or pushing the steering portion so that the partition wall is connected and separated from the neck portion.

The container according to an embodiment of the present invention includes a housing having a first compartment and a second compartment communicating with each other at a neck portion, a thread portion surrounding an opening, a displacement member having a screw portion for rotatably engaging the screw portion of the container, and A partition for sealing the neck portion, wherein the partition moves from the non-sealed position where the first and second compartments communicate with each other to the closed position where the neck portion is closed when the displacement member rotates with the threaded portion engaging the threaded portion. A displacement member is formed, wherein the displacement member has one or more conduits for introducing components into and out of the second compartment through the opening, depending on whether or not the displacement member is in a sealed position. In this embodiment the conduit has and passes through a passageway extending into the container through the opening.

At least one conduit is surrounded by the threaded portion of the displacement member, the opening is cylindrical and the seal may comprise an O-ring seal. The container includes a second seal for sealing one or more conduits. According to another feature of embodiments of the present invention, it may be provided with a feeding nipple attached to the displacement member or the container. The secondary seal is disposed outside of the feed nipple.

Another embodiment of the present invention provides a container comprising a side wall, a dispensing opening at an upper end, a bottom wall, and a partition that divides the container to seal fluid freely into each of the two compartments to hold one of the two components. The vessel has a displacement vertical rectangular member having an upper end connected to the partition wall and a bottom end connected to the bottom wall such that the vertical axial displacement of the bottom wall vertically displaces the displacement rectangular member to move the partition wall.

According to an embodiment of the present invention, the partition wall is integrally connected to the inner side of the side wall through a connecting area which can be broken by vertical displacement, and the rectangular member extends downward from the partition wall to the bottom wall of the container. According to an embodiment of the present invention, the displacement of the rectangular member causes a vertical displacement of the partition wall that destroys the connection area. Breaking the bulkhead creates a flow between the two compartments and allows the contents of the two compartments to mix. The contents of these two compartments are mixed to form a ready-to-use preparation which will then be dispensed.

The bottom wall can be bent to move vertically in the center. It is also possible for the bottom wall to be firmly formed and to have a periphery which can be bent and to be displaced vertically without the whole being bent. In one embodiment of the present invention, the bottom wall may be formed in a downward arcuate in a stationary state and placed in another position that is an upward arcuate which pushes the rectangular member to cause vertical displacement of the septum. In another embodiment of the present invention, the bottom wall is displaced by pulling downwards towards another position that is upwardly arcuate and downwardly arcuate at rest. It can be pulled using the handle fixed to the bottom wall. As can be readily seen, in the above-described embodiment, the container can be operated with one hand.

According to the invention, the displacement member has a safety mechanism for preventing undesirable axial displacement. According to an embodiment of the present invention, the safety mechanism comprises at least one radially protruding lug engaged with a circumferential groove in the container, wherein the displacement member comprises a first angular position and a second angular position at which the at least one lug engages the groove. Rotating between the lugs separates to allow axial displacement.

The displacement member comprises a closure member, for example a breakable seal, which seals the displacement opening, which, once broken, can dispense the mixed formulation from the container. The container has a closure assembly fitted in the opening. The closure assembly may be replaceable and may or may not cooperate with the displacement member. According to one embodiment of the invention the closure assembly comprises a removable stopper. According to an embodiment of the invention, the displacement member has a periphery for displaceably mating with the upper end of the housing and has an outward opening defining a dispensing opening.

According to another embodiment of the present invention, the displacement member is engageably displaced at the lower end of the housing. In general, according to an embodiment of the present invention, the displacement member has a wall defining a bottom wall of the container, having a sealable opening so as to fill the first compartment. According to this embodiment, it has a dispensing opening but is not necessarily different from the sealable opening in the displacement member.

A closure assembly configured to discharge the formulation from the container under control is fitted in the dispensing opening. The closure assembly according to an embodiment of the present invention is configured according to the desired use. For example, in the case of a container for a pharmaceutical preparation, the closure assembly is a penetrating rubber stopper and is suitable for inserting an injection needle to stop the administration of the pharmaceutical preparation; The closure assembly is configured to dispense a predetermined amount of preparation each time; This closure assembly may be formed in the form of a spoon-shaped dispensing unit; In the case of a container for use as an infant bottle, the closure assembly is a nipple shaped and sized to suit each application. The closure assembly may be fitted with an additional cover, such as a cap covering the nipple or a thin film covering the stopper, to secure the closure and remain sterile. In the case of a cap that covers the nipple, the cap may be fitted to close the opening of the nipple to prevent spilling of the liquid constituents during storage prior to mixing the liquid formulation.

The present invention provides closures and dispensing systems suitable for infant feeding bottles. The closure and dispensing system according to the invention consists of a sheet member, a nipple and a coupling member, the sheet member being connected to the bottle to form a unit or fit into an opening, and an annular nipple support surface at the top surrounding the hole. A central hole having; The nipple has an annular skirt or shoulder placed on the nipple support surface and has a dispensing nozzle; The coupling member is adapted to fit against a bottle with one element laid against the annular skirt of the nipple so that it can be pressed against the support surface of the nipple. The nipple assembly is formed so that the container can only be used for single use. For example, the coupling member can be configured to hold the nipple in such a way that it can not be removed and, if removable, can be configured so that the replacement part can no longer be inserted into the container.

According to an embodiment of the invention, the dispensing opening is provided with a filter to filter out undissolved particles present in the formulation. According to another embodiment of the invention, the center opening of the closure system is surrounded by an upwardly protruding sleeve attached to the bottom inner wall of the nipple. According to another embodiment of the present invention, a snap fitting is used to connect to the vessel wall by a coupling member.

The container according to the invention is adapted for various uses. In an embodiment of the invention, the container is used as an infant feeding bottle, in which case the first compartment comprises a liquid, generally sterile water, and the second compartment comprises an infant preparation which is a powder. According to another embodiment of the invention, the container is made for storing a pharmaceutical preparation consisting of two components, the first compartment comprising a liquid, ie water or a sterile salt solution, the second compartment being prior to use Dry particle preparations to be mixed with the liquid, such as antibiotic preparations. Depending on the type of preparation, both components are liquid, one is liquid and the other is dry preparation or both is dry preparation.

The relative sizes of the first compartment and the second compartment can be designed to suit the desired application.

The container according to the invention can be made disposable and the container is generally discarded after one use. The container is also made recyclable. That is, it can be sent back to manufacturers after use to refill. The container may then be made refillable in two components by the end user. The container according to the invention is made and constructed of a material that can withstand the heating of the container in order to warm its contents.

It is advantageous to provide a prepackaged container that can only be used once to prevent the end user from reusing the container. This container is provided to the manufacturer while controlling the quality of the delivered product by preventing the end user from refilling and reusing the container. Prepackaged containers have the advantage of controlling the ratio, quality and sterilization of the transferred mixed formulation and the components used. Disposable containers can be achieved by controlling the material strength and the structure of the container, preventing refilling capability, and breaking the maneuverability of the container and this combination. For example, the container is made of thin plastic material and has a closure system that cannot be removed or reclosed after opening or a seal that cannot be resealed after breaking.

The present invention provides a process for preparing a container for storing a formulation consisting of two separate components that are mixed with each other prior to use. According to an embodiment of the invention, this process is:

(a) a container having a housing including an upper end and a lower end, the housing including an opening at the upper end and an opening separating the container into a second compartment adjacent the first bottom compartment and the opening and a neck portion between the bottom end; To provide;

(b) inserting a first component of the formulation into the container through the opening;

(c) a displacement member is fitted in the housing, the displacement member having a partition for engaging the neck portion with the fluid so as not to leak, the first position where the partition forms a seal without fluid leakage at the neck portion, and between the two compartments. The wall portion can move axially along an axis extending through the neck portion between the neck and a second position separated from the neck so that fluid can flow therein; The displacement member can fit the container into a first position;

(d) the second component can be inserted into the second compartment;

(e) sealing the opening.

According to another embodiment, this process is:

(a) providing a body for use as a housing of a container having an inner surface extending between two open ends and a neck portion between the two ends; One of the two open ends is axially comprised of a wall portion connected to the opening for axial movement, a filling hole for sealing at the wall portion and a partition wall suspended from a wall suitable for forming a seal to prevent fluid from leaking from the neck portion. Is fitted to a movable member; The displacement member is assembled in the body such that the partition defines a first, bottom compartment and a second, upper compartment when the partition is placed in the neck portion;

(b) introducing a first component of the formulation through the filling opening into the first compartment and closing the opening;

(c) introducing a second component into the second compartment through the opening at the other end of the body;

(d) it consists of sealing the opening.

According to the invention this process comprises placing a cover over the opening. In an embodiment of the invention this is done in a sterile or sterile state.

The present invention provides a method for making a liquid formulation from two separate components, which method comprises:

(a) providing one of the aforementioned containers in which each of the two components is stored in one of the two compartments of the container and the displacement member is arranged to seal the two compartments;

(b) move the displacement member axially to the second compartment;

(c) Stir the vessel to mix the two components into the formulation.

In particular when the container is pre-filled at the production location, a feature of the method of preparing the preparation using the container according to the invention is that the ratio between the two components, ie the powder and the liquid, can be precise.

The present invention will be described with reference to specific embodiments for drug containers and infant feeding bottles according to the present invention. Those skilled in the art will appreciate that the same principles can be applied in fields and other applications where it is desirable to store the preparations of two or more components that must be mixed before use, ie, separately.

The following examples relate to a container according to the invention, generally an infant bottle having two compartments, one compartment comprising a powder preparation and the other comprising a liquid such as water. The following detailed description shows various structures and examples, but should not be construed as limiting the invention to the examples described herein. The present invention can be used for various purposes. That is, a container consisting of two or more compartments can contain pharmaceuticals, dietary powders made from liquid and liquid alcohols, and alcoholic beverages that form cocktails with different ingredients, one compartment containing one ingredient and the other compartment being formulated. And another component that is mixed to form water.

The container according to the invention is described as storing a dry powder component and a liquid component, but both components may be liquid or fluid, one may be liquid (or fluid) and the other may be a dry preparation, both dry It may be a preparation. In describing the present invention, materials stored in containers are described using the term "component".

Infant feeding bottle 10 according to an embodiment of the present invention is shown in FIGS. Infant bottle 10 includes a cylindrical housing 12 having a neck portion 16 and an opening 14. This neck portion 16 is partially defined and divides the housing 12 into a first compartment 18 below the neck portion and a second compartment 38 above the neck portion (FIG. 3). The container holds a displacement member 20 that includes a partition 22 having an edge 24 (FIG. 3) that is adapted to engage the inner wall of the neck portion 16 to seal against fluid leakage. Although the material of the structure as well as other means such as neck 16 and edge 24 shape and geometry can be used to seal the fluid tightly, it is fitted with a circular groove 29 provided on the edge 24. Peripheral O-rings 28 may be fitted to prevent fluid leakage.

The partition 22 is connected to the steering portion 30 by one or more downwardly protruding stems 32 forming a connecting wall portion. In an embodiment according to the invention, three radial stems 32 connect the partition 22 to the steering portion 30. In the case of a single stem, it is centered, and in the case of multiple stems it is arranged around. In another embodiment of the present invention, the partition and the steering portion will be connected by a peripheral wall formed with the opening. In another embodiment, the partition wall and the steering portion are connected by the radiation wall portion. The opening 14 has an outer threaded portion 34 around it for screwing into the inner threaded portion 36 in the displacement member 20.

The steering portion 30 has a filling hole 31 through which the contents of the container are dispensed or material is added to the container. The connecting wall portion 32, referred to as a stem, has an opening 35 through the hole 31 so that a passage through the displacement member 20 is formed and the material moves between the inside and the outside of the housing 12. Can be.

In the embodiment shown in Figs. 1 to 3, when the displacement member is screwed into the opening 14, the partition wall is connected and sealed with the inner wall of the neck portion 16 as shown in Fig. 3. In the location of the partition, referred to as the "first state", the partition forms two compartments, the first compartment 18 being under the partition and the second compartment 38 between the partition 22 and the opening 14. Is placed on. In the first state, the portion of the partition forms part of the common wall shared by the two compartments. When the displacement member rotates in the opposite direction, the partition wall 22 moves axially toward the opening 14 and separates the inner wall of the neck portion 16 so that it can move between the two compartments referred to as the "second state". Allow.

The infant feeding bottle 10 has a nipple 42 which is fixed to the upper end of the displacement member 20 by means of the nipple retaining ring 44 and the nipple retaining ring is above the displacement member 20. Snapped into the receptacle 46 at the end. The infant bottle shown herein has a cap 48 that includes a cylindrical portion 50 that engages the outer upper surface 52 of the displacement member 20. The cap 48 is formed to seal the opening 64 provided in the nipple 42 and protects the sterile state of the nipple. Seals made of aluminum foil are also provided in the openings 14 or holes 31 to prevent components or mixed preparations from being discharged out of the container. The outer face 52 of the displacement member 20 has an axial groove 54 that cooperates with the radially inward protrusion 56 at the cap 48. By this connection, when the cap 48 is rotated, it causes rotation and axial movement of the displacement member 20.

The bottle 10 is made disposable in a variety of ways using a thin plastic material for the housing, the nipple retaining ring 44 is made incapable of removing the nipple so that the container cannot be refilled, and the nipple retaining ring The upper end of the displacement member 20 is configured so that the replacement portion cannot be secured back to the container once the 44 is removed so that the nipple can no longer be secured to the container, and once moved in the sealed position, the fluid-sealed seal is no longer The displacement member can be made so that it cannot be deformed.

In the embodiment shown in FIG. 3, the first compartment 18 of the baby bottle stores liquid 60, sterile water, and the second compartment 38 is filled with a powder preparation component 62. This material can be changed and the first compartment 18 holds the powder preparation component 62 and the second compartment 62 holds the liquid.

The method for producing infant bottles of the kind shown in FIGS. 1 to 3 is shown step by step in FIG. 4. It is preferred to be manufactured under sterile conditions using sterile ingredients to ensure the sterile condition of the bottles. As shown in FIG. 4A, in a first manufacturing step, liquid 62, which is a first component, for example sterile water, is introduced into housing 12. Although the first component is preferably inserted without a displacement member placed on the housing, the first component may be inserted with a displacement member placed on the housing. For example, the first component can be introduced with a displacement member overlying the housing in a second state such that the first component can pass into the first compartment, the displacement member in the first state and thereafter the second component The first component can pass into the first compartment by moving axially in the second state before being added. As a next step shown in FIG. 4B, the displacement member 20 is screwed into the opening 14 of the housing such that the partition wall 22 is sealingly mated with the inner wall of the neck portion 16. In the next step shown in FIG. 4C, the opening with the nipple 42 is sealed by the retaining ring 44 (FIG. 4D) and then by placing the cap 48 over the nipple (FIG. 4E) the opening 14 and the hole 31. A second component, for example a powder formulation 62, is introduced into the second compartment 38 through). In this position the cap 48 seals the opening 64 in the nipple 42.

When preparing an infant bottle according to the invention in a manufacturing plant, it is ensured that good quality water is used. Water of good quality may be defined as water having a mineral component and free of contaminants such as heavy metals, bacteria, microorganisms and harmful substances, which may be improved by distillation. In addition, especially in the case of newborns, quantification of powder preparations and liquids can be achieved by factory automation to ensure the proper proportioning and mixing of the components and to provide optimum mixing conditions that are neither too thin nor too thick.

5 shows how to prepare a baby bottle. In the first step (FIG. 5A), the displacement member 20 is rotated so that the partition wall 22 moves in the axial direction and this edge separates the inner wall of the neck portion 16. In this position (“second state”) two compartments (first and second compartments) may flow through each other. This raises the partition 22 away from the neck 16, allowing the second component 62 to fall into the first compartment 18. In this state, the cap 48 is held in the housing so that the mixture and nipple 42 remain sterile. By stirring, shaking or rotating in the direction of arrow 68, the dry preparation 62 and the liquid 60 are mixed with each other to form the liquid preparation 70. By removing the cap 48, the liquid formulation can be dispensed through the opening 64 of the nipple 42.

6 and 7 show a container consisting of two compartments, denoted 310, wherein the intermediate seal is externally controlled by the rotation of the threaded displacement member. The two-compartment vessel 310 includes a housing 312 having a restricted neck 318 defining a first compartment 314 and a second compartment 316. The first compartment 314 and the second compartment 316 are interconnected at the compressed neck portion 318. The second compartment 316 includes an opening 320 having a threaded portion 322 around the perimeter.

The two-compartment vessel 310 includes a plug prosecution and displacement member 324 as precisely shown in FIG. 8. Displacement prosecution 324 has a threaded portion 326 for rotationally mating threaded portion 322 and a partition 328 for sealing neck portion 318. The displacement member 324 is in the non-sealed position (second state) shown in FIG. 7 in which the first and second compartments 3145, 316 communicate with each other when the threaded portion 326 interacts with the threaded portion 322 by rotation. The partition wall 328 is formed so that the partition wall 328 moves from the sealing position (first state) shown in FIG. 6 to which the neck portion 318 is sealed.

In general, the partition 328 is formed to complement the neck portion 318 and is formed of silicone rubber or the like and includes an elastic O-ring seal 334 secured between opposing pieces of the molded plastic assembly. In addition, a planar or other type of adjacent face may be provided to seal the neck portion 318. The seal, which is made leak-free, formed by the partition wall having the neck portion can be reformed. The two compartments can be resealed. In addition, the partition wall and the neck portion are configured so that the seal cannot be reshaped.

According to an advantageous feature of the embodiment according to the invention, the displacement member 324 comprises one or more conduits 330 to be introduced into the second compartment 316 through the opening 320 when the displacement member 324 is in the sealed position. do. One or more conduits 330 are surrounded by threaded portions 326 of the displacement member 324. Thus, as shown, the displacement member 324 features a cylindrical threaded portion 326 having four conduits 330 separated by longitudinal radiation walls. The longitudinal radiation wall connects the partition 328 with the threaded portion 326. The conduit can also be formed around the displacement member 324 as a channel in the threaded wall. In this case the two compartment container 310 includes a second seal 332 for sealing the conduit 330. In another implementation method of the invention, the displacement member 324 is made of a solid structure. In this case, a separate sealable opening is provided to allow filling and dispensing of the second compartment 316.

According to a feature according to an embodiment of the present invention, the displacement member 324 can move or rotate to selectively seal or open the neck portion 318 outside of the two-compartment vessel 310. The displacement member 324 has an upper wall portion 336 extending beyond the threaded portion 326 so that the displacement member 324 is fixed for this purpose. The displacement member 324 can be manually rotated by the flange member 338 attached to the outer circumference of the upper wall portion 336. The assembly and filling process of the two-compartment container 310 is the same as that shown in FIGS. 4-5 and the bottle 10.

When used in infant formula feeding, bi-compartment containers are preferably used as feeding bottles. For this purpose, the two-compartment container has a nipple attached around the outside of the displacement member. 6 and 7, the flange member 338 is mounted on the outside of the nipple 340 and the secondary seal 332 is on the outside. This allows the secondary seal 332 to serve several functions. That is, it is attached to the shoulder of the second compartment 316 to seal the second compartment 316, to protect the sterilization state of the nipple 340, and to serve to wrap the flange 338 is not twisted open.

9A-9C illustrate a process and structure for filling two compartment containers 80 in accordance with another embodiment of the present invention. The container 80 is formed from a tubular body 82 having an opening 84 at the end of the body constituting the bottom of the container and a second opening 86 at the opposite upper end. A compressed neck portion 88 is placed between the upper and lower ends. The vessels 10, 310, 80 are formed to have a compressed neck portion, which may be formed as shown in FIG. 13.

Displacement member 90 having end wall 92 having sealable filling opening 94 and partition 96 suspended from end wall 92 by stem 98 is screwed into peripheral portion 100. Tighten to end 84 by tightening. By this screw-assembly, the displacement member 90 rotates to cause an axial displacement of the partition wall 96 with respect to the neck portion 88. After the displacement member 90 engages the body 82, in particular the partition 96, which forms a seal-free seal with the neck portion 88, the first component 101, ie, the water 94, forms a hole 94. It is introduced through and then sealed by the stopper 102.

The container is then rotated to the position shown in FIG. 9B with the opening 86 facing upwards. The second component 104, ie the powder formulation, is introduced through the opening 86 sealed by the closure assembly 106. The closure assembly 106 has a closure 108 that can be resealable.

Preparing the container of FIGs. 9A-9C for use and dispensing the formulation is shown in FIGS. 10A and 10B. In the first step shown in FIG. 10A, the displacement member 90 is rotated such that the partition separates from the neck portion 88 to allow the mixture of components 101, 104 to form a liquid formulation 110. After mixing and homogenizing, the container may rotate to dispense through the closure 108 as shown in FIG. 10B.

A vessel 120 according to another embodiment is shown in FIGS. 11A-11F. The vessel 120 is similar to the vessel 80 and the same filling method, as shown in FIGS. 9 and 10, but is disposed differently in the assembly 122 for administering the liquid formulation 124.

11A to 11F show each process of preparing and dispensing a preparation. Assembly 122 defines a compartment 126 formed between bottom wall 130 and lid 128 of assembly 122. Lid 128 seals the fluid with the upper end of the assembly. This assembly 122 has a skirt 132 that is secured with screws 134 in the opening of the vessel 120. This assembly has an opening 136 that has a connection between the interior space 138 of the container 120 and the compartment 126 in the position shown in FIGS. 11A-11C.

After mixing the two components, as shown in FIG. 11B, the vessel is rotated so that the liquid formulation fills compartment 126 through opening 136 (FIG. 11C). The assembly 122 can then be rotated so that the opening 136 can be closed (FIG. 11D) and the container 120 can be rotated in a vertical position (FIG. 11E), and the sidewall 131 of the closure assembly can be a liquid formulation or The seal forms a seal that can not be resealed so that the separated components do not leak from the container. O-ring 133 assists in forming the seal to prevent fluid from leaking. The lid 128 can then be removed and the contents of the compartment 126 can be dispensed (FIG. 11F).

A container 150 according to another embodiment of the present invention is shown in FIGS. 12A-12E. This container 150 is different from the containers 80, 120 having the properties of the closure and dispensing assembly 152. The dispensing method is shown in FIGS. 12A-12E.

The dosing assembly 152 includes an end wall 155 having a skirt 153 along a peripheral edge with screws 151 that engage screws 154 that cooperate with the opening of the container 150. do. End wall 155 has a hole 156 into which the cylindrical center pipe 158 fits. Seals are provided to prevent fluid leakage between the central pipe 158 and the end wall 155 so that no components of the mixed liquor formulations leak out of the vessel. The center pipe 158 is open to communicate with the dosing compartment 157. Compartment 157 is sized to hold an appropriate set amount of liquid formulation. The upper side of the compartment 157 is formed to have a number of small holes 159, which are structured so that the liquid formulation enters the dosing compartment 157. Cap 149 is provided in the center pipe 158 and has a seal to prevent fluid from leaking.

In FIG. 12A, the two-compartment container stores the two components separately in the case of having liquid in the bottom compartment and dry powder in the upper compartment until the liquid preparation is ready. When the liquid preparation is prepared, the displacement member is moved such that the upper compartment and the lower compartment are connected to each other as shown in Fig. 12B. The entire container can be moved by stirring or shaking to make the liquid preparation easier. In FIG. 12C, the container is turned upside down and the liquid formulation flows into the dosing compartment 157 through the small hole 159. When the dosing compartment 157 is filled, the container rotates back to the vertical position as shown in FIG. 12D. The cap 149 is then removed and the liquid formulation is dispensed through the center pipe 158 as shown in FIG. 12E. The central pipes 158 all have a wider cross section than the small holes 159, and the dispense amount in the dosing compartment 150 before feeding the additional formulation through the small holes 159 to the dosing compartment 157. Distributed as shown in 12d.

The container 160 according to another embodiment of the present invention is shown in FIGS. 13A-C where the bottle 160 has a body 162 and a lower end 164. The displacement member 170 has a center hole 174 sealed by a stopper 176 and a bottom having a partition wall 178 connected to the bottom portion 172 by a cylindrical wall 180 formed with the opening 182. It is formed to include the portion 172. Instead of the compressed neck portion, the housing 162 has an inwardly radiating wall 184 that defines the neck portion 185, which cooperates with the partition 178 in the state shown in FIG. A seal is provided between the 192 and the upper compartment 190 to ensure that no fluid leaks. In FIG. 13, the housing 162 has a sleeve 183 which includes an inwardly radiating wall 184 at its upper end which is sealed off at the partition 178 to form a seal to prevent fluid from leaking. Cooperative with section 186. The seal is made to form a seal that can be reshaped (ie resealable) and that the partition cannot be reshaped after it has been separated from the neck. The displacement members can be moved axially to the position shown in FIG. 13C so that the compartments 190 and 192 are connected to each other for the fluid to move. The liquid formulation is then mixed and dispensed through the nipple closure, which nipple closure is structured according to methods known in the art or as described above.

In FIGS. 13A-C, the bottom end 164 is formed to have a helical groove 166. Groove 166 slides into knob 168 between the first position indicated by " OFF " located in FIGS. 13A and 13B and the second position indicated by " ON " shown in FIG. 13A. By rotating the knob 168, the knob causes an axial displacement of the displacement member 170. Detailed parts may be provided in the groove 166 to hold the knob 168 in the "on" or "off" position.

Infant feeding bottle 200 according to another embodiment of the present invention, shown in FIGS. 14A-B, includes a housing 202 that is generally cylindrical with a compressed neck portion 204. As shown in FIG. 14A, a downward groove cooperating with the annular protrusion 210 protruding from the partition 212 to provide a seal that ensures no leakage of fluid between the upper compartment 216 and the lower compartment 214 of the vessel. An annular mating member 206 formed with 208 protrudes inward from the neck portion 204. The partition 212 constitutes a portion of the displacement member 218 that includes a user manipulation portion 220 having two pins 222 received in the helical groove 224. By rotating the user operating portion 220, the displacement member axially moves downward to the position shown in FIG. 14B.

The displacement member includes a bottom portion 226 having an opening sealed with a stopper 228. The partition 212 is connected to the bottom portion 226 by a cylindrical wall 225 having an opening 227. The stopper 228 allows one component, for example a powdered infant formulation, to enter the bottom compartment 214. The infant bottle 200 includes an opening 238 fitted with a nipple 230, the nipple being protected by a cover 232, which can be attached to the housing by a snap fit or cooperating threaded portion. . In the embodiment of FIGS. 14A and 14B, upper compartment 216 is sized to store liquid and fluid material while bottom compartment 214 is sized to store dry material. Liquid and fluid are added to the dry material in the lower compartment for better mixing. For example, storing the powder in compartment 216 may prevent nipples from being ineffective.

4C is an exploded view of FIGS. 4A-B. The housing 202 is constructed by assembling the main tank 250 and has a neck 204 and an inwardly annular connecting member 206, which ensures that the main tank 250 and the nipple seat 260 are free of fluid leakage. Nipple sheet 260 is ultrasonically welded to form compartment 216. The nipple 230 fits into the opening 238 at the upper end of the housing 202, which is fixed in place by the nipple retaining ring 240. The nipple fixing ring 240 is connected to the shoulder 234 formed in the nipple 230 and is fixed in place by a lip 262 formed on the nipple sheet 260 and a protrusion 236 formed on the nipple 230. . The nipple retaining ring 240 can couple the nipple 230 to the container by snapfitting over the lip 262.

An nipple 230 assembly is made over a housing 202 having a nipple retaining ring 240 so that the container is for single use. For example, nipple retaining ring 240 may be designed to engage lip 262 so that if the ring is removed it cannot be secured back to the container. In addition, the nipple fixing ring 240 may be designed such that it cannot be removed after snap fitting to the nipple sheet 260. Other properties of containers suitable for disposable use are the ease of their materials and construction, and the thickness of the materials used.

14C shows the displacement member 218 with the steering ring 220. The displacement member 218 can be inserted into the bottom end of the housing 202 and the pin 222 can be inserted into the helical groove 224 and the aperture of the displacement member 218 to attach the steering portion 220 to the displacement member. The steering portion 220 is fitted and positioned over the lower end of the housing 202 so as to snap fit through 225. The seal formed by the annular protrusion 210 at the partition 212 and the groove 208 at the annular mating member, depending on whether the container is used for single use or over multiple uses, is a disposable seal or a reformable seal. It can be designed to make. It is desirable to make the container disposable to ensure the sterility and correct proportions of the container, the sterilization and the quality of the components. In the embodiment shown in FIGS. 14A-C, the annular protrusion 210 and the groove are made suitable for single use by ultrasonic welding the two parts, the welded joint being pulled apart during the movement of the displacement member 218. . The annular protrusions and grooves are made to be resealable. In other words, the seal can be broken and reshaped by the movement of the displacement member.

It will be appreciated that the process of preparing and dispensing for filling and using the container shown in FIGS. 13 and 14 is similar to the embodiment described in FIGS. 9A-C and 10A and B.

A baby bottle 410 according to another embodiment of the present invention is shown in FIG. 15. The container includes a cylindrical housing 412 having an opening 418 at the top that fits into the side wall 414, the bottom wall 416, and the closure assembly 420. A lid 421 is attached to the lower end of the container, the function of which will be described in detail below.

The closure assembly 420 consists of a nipple 422 made of silicone rubber, latex rubber, or other FDA approved material, and is fitted to the filtration element 430 to filter food particles dissolved in the liquid formulation. Bottom inner surface of leg 432 or inclined support structure and nipple 422 having an annular skirt 424 mounted to a sealing member 426 having an annular portion 428 defining a central hole 429. It has an upward cylindrical ring portion 431 supporting it. The edge of the annular portion 428 is received in the circumferential shoulder 434 at the upper end of the side wall 414 and the end of the support structure 432 lies on the inner surface of the side wall 414. The nipple is held by a mating member 436 having a stepped cross section. The mating member 436 includes a first horizontal portion 442 pressing over the skirt 424, a second annular horizontal portion 444 lying in the circumferential recess 446 of the seal member 426, and an annular bulge ( bulge 450 has a downward portion 448 that engages shoulder 434. This connection method by the connecting member 436 attaches the fluid of the closure assembly 420 so as not to leak. By using a rubber circular portion lying underneath the horizontal portion 444, leakage of fluid can be prevented.

As described with reference to FIGS. 14A-C, the nipple assembly is made such that the container is suitable for single use by making the connecting member non-refixable or removable.

As shown in FIG. 15, the closure assembly 420 fits into a lid 452 having a downwardly protruding cup member 454 receiving the upper end of the nipple to seal the opening 456.

The vessel includes two compartments, a top compartment 460 and a bottom compartment 462 separated by a septum 464 integrally coupled to the sidewall 414 via the annular connecting portion 466. A rectangular connecting member 468 that includes a cavity 470 having a reinforcing rib 474 and an opening 472 at an upper end thereof extends downward from the partition wall 464. The bottom end of the rectangular member 468 is received and connected to the cup member 476 protruding upward from the bottom wall 416.

The partition 464 has a separation portion formed between the compartments 460 and 462 so that fluid does not leak. When moving vertically by pushing the bottom wall 416 up, the connection area 466 is broken to join the two compartments and mix the contents. In an embodiment of the present invention the seal formed by the partition wall 464 cannot be reshaped and the container is suitable for single use. To prevent undesirable displacement of the bottom wall 416, it is covered with a lid 421, which must be removed to push the bottom wall 416. The cover 421 which is difficult to unpack is attached to the removable portion by using a snap fit device, a screw connection or a breakable attachment area. In addition, the cover difficult to remove the package may be formed of a thin film that can be removed before use.

16A-16E illustrate a method of making a container, each compartment having one component of an infant formulation, ie, a powder formulation in the bottom compartment 462 and water in the upper compartment 460. However, this can be configured in reverse. That is, it may have a powder preparation in the upper compartment and water at the bottom. This container is provided in the manner shown in FIG. 16A without the bottom wall 416 and the closure assembly 420 or is disposed oppositely. In a first step shown in FIG. 16B, compartment 462 is filled with a dry powder formulation 490 introduced through open end 492 via dosing dispenser 94. In the next step shown in FIG. 16C, a bottom wall 416 having a concave shape inside the annular skirt portion 496 is installed and attached to the open end 492 of the container. Advantageously, other forms of bonding methods, such as glue bonding, thermal welding or the like, are possible, but the annular skirt portion 496 is attached to the inner surface of the wall 412 by sonic welding. The cup member 476 is then secured to the bottom end of the rectangular member 468 by sonic welding performed by inserting the probe 497 through the opening 472 of the cavity 470 and the opening 418 of the vessel. .

In the next preparatory step shown in FIG. 16D, a lid 480, which is difficult to remove the package, is installed over the end 492 and the vessel is rotated to a vertical position and the liquid (generally water) 498 is a dispensing tab 400. It is introduced into the compartment 460 through. Then, in the next step shown in FIG. 16E, the closure assembly 20 fits into the opening 418.

The process of preparing the container for use is shown in FIG. 16F. The lid 480, which is difficult to remove the packaging before use, is removed at the lower end of the container and the force is applied in the vertical direction at the bottom wall 416, as indicated by arrow 404, such that the wall 416 is shown in FIG. 16F. In position, the rectangular member 468 and the partition wall 464 are moved in the vertical axis direction. This breaks the partition 464 at the connection 466 so that the contents of the two compartments can be mixed in the direction of the arrow 404. After mixing, the preparation is ready to dispense and use through the opening 456 of the nipple 422 after removing the cap 452.

17 illustrates an infant bottle 510 according to another embodiment of the present invention. This embodiment is essentially similar to the embodiment shown in FIG. Distinguishing from the bottle of FIG. 15, the bottom wall 516 of FIG. 17 is bent upward with an integral handle 580 in a space defined by the base member 582 of the bottom.

As shown in FIG. 18, when pulling the handle 580 downwards in the direction of arrow 586, the wall 516 bends downward and this movement breaks the connection 566, similar to the embodiment of FIGS. 15 and 16. Mix the contents of the compartment. The handle 180 has a number of connecting teeth 584 that serve to hold the bottom wall 516 in a downward arched position to engage the accessory wall 588 as shown in FIG. 17. Once the contents of the two compartments have been mixed and a preparation ready for use has been formed, it can be dispensed through the opening 556 of the nipple 522 after removing the cap 552.

The present invention can be applied to a variety of two-compartment containers. Possible applications include foodstuffs, beverages and pharmaceuticals, as well as two liquid constituents, one liquid and one solid. It is to be understood that the embodiment according to the present invention focuses on a container having at least two compartments that are disposable, prepackaged, which can be easily and economically made ready to be disposed of.

This container has an accessory device for dispensing the final mixture. It can be applied to measuring cups for dispensing measured units such as drugs and feeding devices designed for children and the elderly. By way of example only, the present invention is described with reference to a pediatric preparation bottle structure.

The container according to the invention can be filled under a wide range of controlled conditions for a variety of applications. This entire assembly process is sterile and uses sterile components. In addition, compartments containing one or two compartments and powder components will be partially vented. And an inert gas such as nitrogen will be introduced above or below atmospheric pressure to minimize oxidation of the contents during storage. Other special conditions, such as controlling humidity, may be applied as required.

In the case of pediatric preparations in which the mixture needs to be heated to dissolve, the two-compartment container is formed entirely of nonmetallic material so that the contents can be directly heated in the microwave. Alternatively, the two-compartment container may be made of a material capable of heating the contents by placing the container in a boiling liquid such as water. Many materials, including plastics such as polypropylene, are used in embodiments of the present invention. Feed nipple and bulkhead part are made of silicone rubber. When used to store or dispense pharmaceuticals and foodstuffs, the materials in the container must meet regulatory requirements such as those provided by the US Food and Drug Administration and other jurisdictions.

It is to be understood that the foregoing detailed description is merely illustrative and that various modifications may be made within the scope of the present invention.

Claims (58)

In a container for storing the two substances which must be mixed separately to provide the preparation and for dispensing the preparation: A housing having a dispensing opening and a neck portion; And A displacement member disposed in the housing with a partition suitable for forming a seal that prevents the fluid from leaking; The displacement member can move axially between two positions along an axis extending through the neck portion, the two positions being a first sealing position close to the neck portion and a second non-sealing position in which the partition moves from the neck portion. ; Wherein the partition shares a portion of the partition and has two compartments in the sealed position that seal the fluid separated by the portion from leaking, allowing the fluid to flow between the two compartments when moving from the neck portion. The container of claim 1, wherein the neck portion has a circular cross section and the partition is circular. 2. A container according to claim 1, comprising a housing having a clamped neck portion having a narrow cross section relative to an adjacent portion of the housing. The container of claim 1, wherein the neck portion includes a wall extending radially inwardly from the housing. 4. The container of claim 3, wherein the neck portion includes a wall extending radially inward from the housing. The container according to claim 1, wherein the partition wall is connected to the control portion of the displacement member by one or more connecting walls. 7. The container of claim 6, wherein the one or more connecting walls are longitudinal radial walls. 7. A container according to claim 6, wherein the one or more connecting walls are cylindrical with openings. The container of claim 1, wherein the partition forms a seal that engages the inner wall of the neck portion to ensure that the fluid does not leak. The container of claim 1, wherein the partition is suitable for forming a seal that can be reshaped. 10. The container of claim 9, wherein the partition includes an O-ring to provide a seal that ensures that the fluid does not leak. 5. The wall of claim 4 wherein the septum has a circular protrusion and the radially inwardly extending wall has a circular groove, the circular protrusion and the circular groove being configured to cooperate with one another to cooperate to form a seal that prevents fluid from leaking. Container characterized in that the. The container of claim 1, wherein the container is made suitable for single use. 14. The container of claim 13, wherein the septum and neck portion are made such that a seal that prevents fluid from leaking is formed only during the first fill of the container. 15. The container of claim 13, comprising means for preventing refilling of the container. 16. The container of claim 15, comprising a closure member that cannot be removed such that it is inaccessible to one of the first and second compartments. 14. The container of claim 13, comprising a closure assembly that cannot be relocked after removal to prevent the contents of the refilled container from being dispensed. The container of claim 1 comprising means for dispensing a solution to the baby. 19. The container of claim 18, wherein the infant dispensing means comprises a feeding nipple having an opening. The container of claim 1 comprising a closure member for sealing the dispense opening. 21. The container of claim 20, wherein the closure member rests outside the feeding nipple to seal the opening in the feeding nipple. The container of claim 6, wherein the displacement member is disposed in the dispensing opening. The container of claim 1, wherein a passage is formed in the displacement member such that material is added to or removed from the container. 24. The container of claim 23, wherein the passageway communicates with the dispensing opening. The container of claim 1, wherein the displacement member is displaced by a rotational motion. The container of claim 1, wherein the displacement member is displaced by pushing or pulling in an axial direction. 2. A screw according to claim 1, comprising a threaded portion provided in the displacement member and a threaded portion surrounding the displacement opening, wherein the displacement member is placed in a dispensing opening having a threaded portion that mates with the threaded portion to move axially by rotational motion. The container which can be characterized. 23. The container of claim 22, wherein the displacement member has a passageway such that the interior of the container communicates with the outside of the container. 7. The container of claim 6, comprising a flange member attached to the outside of the container and the outer circumference of the displacement member steering portion to facilitate movement of the displacement member. The container of claim 1, comprising means for preventing undesirable axial movement of the displacement member. 31. The device of claim 30, comprising a closure member for closing the dispensing opening and the means for preventing undesirable axial movement comprising at least one radially projecting lug in the closure member and a circumferential groove in the displacement member. Courage to do. The container of claim 1, comprising a sealable opening at the bottom end of the housing. 33. The container of claim 32, comprising a removable stopper configured to provide a sealable opening at the bottom of the housing to prevent fluid from leaking. 33. The container of claim 32, wherein the displacement member fits into the opening at the bottom end of the housing. The container according to claim 1, wherein the partition wall is integrally coupled to the side wall of the housing at the neck portion and the displacement member breaks the partition wall connected to the neck portion when the displacement member moves axially. 36. The container of claim 35, wherein the partition is integrally formed with the neck portion by one of ultrasonic welding, thermal welding, or bonding by adhesive. 36. The container of claim 35, wherein the partition is integrally coupled to the sidewall by a circular connection and the partition is separated from the sidewall by breaking at the connection. 36. The container of claim 35, comprising a bottom wall and wherein the displacement member is movable by pushing or pulling the bottom wall. 39. The container of claim 38, wherein the bottom wall has a flexible portion that is made to be movable. 20. The container of claim 19, wherein the feed nipple is held at the displacement member by a nipple coupling member that is sealed at the upper end of the displacement member and cannot be removed. 2. A container according to claim 1, comprising means for dispensing a predetermined amount of preparation. 42. The volumetric compartment of claim 41, wherein the means for dispensing a set amount of preparation comprises a closure and dosing assembly cooperating with the dispensing opening, the compartment having a lid, the opening and the bottom wall sealing the dispensing opening. And the closure and dosing assembly move between a first position in which the sidewall opening communicates with the interior of the container and a second position in which the sidewall opening is closed and the assembly can hold a set amount of formulation. The container which can be characterized. In a container where the two components are stored separately and mixed before use, (a) a housing having a neck portion defining a first section and a second section communicating with each other at the neck portion, the second section having a screw portion surrounding the opening; (b) a displacement member having a threaded portion for rotational mating with the threaded portion of the neck and a partition wall suitable for forming a seal that seals the fluid from leaking in the necked portion, the displacement member engaged with the threaded portion; When rotating, the partition is formed such that the partition moves from a non-sealed position in which the first and second sections communicate with each other to a sealed position in which the neck portion is sealed to form first and second compartments that share a portion of the partition as a common wall, The displacement member has one or more conduits for introducing components into the housing through openings; (c) a closure member for closing one or more conduits. 44. The container of claim 43, wherein at least one conduit is surrounded by a threaded portion of the displacement member. 44. The container of claim 43, wherein the opening is cylindrical and the partition includes an O-ring seal. 44. The container of claim 43, comprising a steering portion attached to the outer periphery of the displacement member to facilitate manual rotation of the plug component. 44. The container of claim 43, comprising a feed nipple attached around an outer circumference of the displacement member. 48. The container of claim 47, wherein the closure member is located outside of the feeding nipple. A prefilled and packaged disposable, two-compartment container for dispensing a formulation formed by storing two components separately and mixing the two components, (a) a housing having a circular wall extending radially inwardly with an neck portion located between an upper end and a bottom end that has an opening at each of the upper and bottom ends and divides the housing into an upper section and a bottom section; (b) a non-removable nipple assembly in communication with the upper opening of the housing to form a dispensing opening; (c) a partition at a first end adapted to form a seal that seals the fluid from leaking when engaged with the circular wall, and includes a steering portion on the outside of the housing to move the displacement member, the partition A displacement member fitted to the bottom end of the housing including a connecting wall having an opening extending between the control portion and the control portion, the opening comprising a opening at the second end; And (d) a closure member for sealing the displacement member opening, the displacement member comprising a circular wall and partition wall forming a common wall dividing the housing into two separate compartments that seal the fluid leakage and a seal that seals the fluid leakage. Wherein said interlocking first position is movable between a second position in which the partition is removed from the neck portion such that the two sections are in communication with each other. 50. The container of claim 49, wherein the partition has a circular protrusion and the inwardly radial wall has a groove, the protrusion and the groove being made to join together to form a seal that seals the fluid from leaking. 51. The manipulator of claim 50, wherein the bottom end of the housing has a helical groove and the steering portion has a pin that fits within the helical groove so that the displacement portion can move between the first and second positions by rotating the steering portion. Courage to do. 50. The container of claim 49, comprising a filtration component located between the container contents and the dispensing opening. 50. The container of claim 49, wherein the dry formulation is stored in the bottom compartment and the liquid is stored in the upper compartment. 50. The container of claim 49, wherein the material of the structure is resistant to sterilization processes such as spinning and gas treatment. 50. The container of claim 49, wherein the container is packaged to protect the component from ultraviolet light, gas and steam. In the process of making a container holding two separate components of the preparation for mixing with each other prior to use, (a) providing a container comprising a housing having an opening at the bottom end, an upper end, the housing separating the container into a first lower section and a second section adjacent the opening and a neck portion lying between the bottom end; (b) introducing a first component of the formulation through the filling hole into the first compartment and sealing the hole; (c) fitting the displacement member into the housing, the displacement member including a partition having an edge suitable for engaging and sealing the inner wall of the neck portion, the first position and the edge of which the edge of the partition engages the inner wall of the neck portion; The inner wall can be moved axially along an axis extending through the neck portion between the second positions allowing the fluid to flow between the two compartments; The displacement member is fitted into the container in the first position; (d) introducing a second component into the second compartment through the opening at the other end of the body; (e) a process for producing a container, characterized in that the opening is sealed. In the process of preparing a container holding two separate components that are mixed with each other prior to use to form a preparation, (a) providing a body for use as a housing of a container having two open ends and an interior space extending midway between the neck portion between the two ends; One of the two open ends is fitted to the axial displacement member which is sealingly connected to the inner wall of the neck portion and the wall portion sealingly connected to the opening, the filling opening which can be sealed at the wall portion and the neck portion to allow the axial movement. A bulkhead suspended from the wall portion having a suitable edge; The displacement member is fitted in the body such that the partition engages a neck defining a first bottom compartment and a second upper compartment; (b) introducing a first component of the preparation into the container through the filling opening and closing the opening; (c) introducing a second component of the formulation into the second compartment through the opening at the other end of the body; and (d) sealing the opening. In a method of making a preparation from two separate components, (a) providing a container according to claim 1, wherein each two components are stored in one of two compartments of the container; (b) axially move the displacement member to the second compartment; (c) A method of making a preparation by stirring the vessel to mix the two components to make a preparation.