KR20000005357A - Method for treating pathological conditions of tissues with non-coherent radiation and device therefor - Google Patents

Abstract

PURPOSE: A method for treating pathological conditions of tissues with non-coherent radiation and a device thereof are provided to have a wavelength of 1 to 56 micrometers as a function of its linear polarization and time modulation which are selected according to the type of disorder. CONSTITUTION: This invention relates to a method for treating pathological conditions of tissues with non-coherent radiation, wherein a periodic infrared irradiation is carried out for 1 to 20 minutes at a radiation power density of 50 to 300 MW/cm¬2 over 1 or 2 days while taking into account the time for stopping the pain syndrome during healing of said tissues. Irradiation is performed above a section of the skin which is located above the organ responsible for the spreading of the disease triggered by a rupture in the exchange, fermentation and regeneration processes in the tissues. The radiation has a wavelength of 1 to 56 micrometers as a function of its linear polarization and time modulation which are selected according to the type of disorder. A device receives an electric control signal for a control system (2) from additional power sources and adjusts the corresponding characteristics of the radiation emitted by a light emitter (3). The radiation source is previously calibrated according to the density of the radiation flow. The light emitter (3) may consist of a wide- and semiconductor silicon luminescent diode with a wavelength of non-coherent infrared radiation between 1 and 56 micrometers and an ultra-hallow p-n junction. The power source (1) is connected along the plane (a) of the p-n or n-p junction and ensures current flow through the doped p-n or n-p junction. The control system (2) comprises leads (c, d, e) for additional sources of electrical field, said leads being connected to the luminescent diode so that the field will act along the plane (a) of the p-n junction and prevent backward or direct displacement on said p-n junction.

Description

Method and apparatus for treating pathological diseases of tissues by non-interfering radiation

A method of treating diabetic vascular disease of inferior limbs, including intra-blood irradiation with low-frequency IR radiation, is known (RU, C1, 2049500, December 27, 95). There is a known method of treating diabetes that directly irradiates liquid blood components using interfering radiation (RU, C1, 2018329, August 30, 94). The methods include the direct effect of internal irradiation on the blood. However, these methods are unlikely to affect the physiological processes of tissue cells, or their effects are modulated by a number of nonregulatory factors. In addition, the interfering IR radiation used in this case is characterized by a low degree of tissue penetration, which makes the radiation effect on the tissue structure less organic and consequently more rigid.

Devices for general local body heating are known to provide deep IR radiation penetration into the body (DE, C, 4113803, 1994). However, since the therapeutic effect of this device is provided by an increase in tissue temperature, this leads to increased necrosis and tissue drying in the course of treatment, thereby promoting the development of secondary inflammation and an added risk of vasodilation in pathologically altered tissues. Involves factors.

Methods of treating skin damage are known to be based on the effects produced by monochromatic rays of pulses in the red wavelength band (RU, C1, 2032432, April 10, 95). However, the light pulse method is applied within a limited red wavelength band since the treated tissue is exposed to light having a wavelength of 0.6 to 0.69 μm at a reduced power density of 5 to 10 mW / cm 2. Thus, no therapeutic effect can be produced for all types of diseases involving metabolic disorders.

Multiwavelength medical lasers produce pulsed beams of electromagnetic energy and secondary beams of electromagnetic energy with wavelengths in the visible part of the optical spectrum, both of which are known to affect tissue simultaneously (US, A, 5304167, 19.04.94). However, this invention uses wavelength energy for surgery rather than treatment.

Thermal stimulation devices are known to affect tissue with IR radiation to stimulate tissue action. However, the stimulus used for that purpose is by heat (RU, C1, 2045969, January 20, 95).

Methods of biologically stimulating active sites are known to stimulate physical action using IR range wavelengths that are characterized by better penetration into the skin (RU, A, 93003767, July 27, 95). However, the irradiation wavelength ranges from 0.8 to 3 μm, and sources in this range are located over biologically active sites that affect systemic function rather than organs that regulate the course of the disease and do not account for disease.

There is a known method for the treatment of bleeding in hemophilia patients based on light stimulation of the affected muscles and joints with light (US, A, 5161526, November 10, 92). However, this method is only applied to stop bleeding and increase blood coagulation using wavelengths in the range of 5 to 1.1 μm that are ineffective in treating all medical indications typical of all kinds of diseases in question.

Methods that affect biological organisms are known to use modulated energy, such as IR energy waves, to optimize the functionalization of the biological organism's energy system and to affect sick organ parts (RU, A, 93015098, 10 September 95). However, this method not only cures redox action that causes slowing of blood flow and functional, anatomical and morphological changes in all kinds of tissue structures, but also impairs tissue capillary circulation, vascular circulation and lymph flow. Treatment does not include affecting metabolism, regeneration and enzymatic activity in tissues. In addition, the resulting effect does not increase the therapeutic efficiency compared to the optimal therapeutic effect for diseases caused by disorders of metabolism, regeneration and enzymatic activity in tissues.

Finally, the closest to the proposed treatment is the treatment of gastric and duodenal ulcers, which range from 50 to 300 mW / cm 2. IR irradiation with power density involves percutaneous irradiation of the mucosa area affected by the disease for 1-20 minutes (RU, A, 94019587, 1996). However, the efficiency of this method is relatively low because it is irradiated directly through the skin located above the affected mucosa area, and thus cannot produce optimal effects on tissue metabolism, regeneration and enzyme action. . This radiation has a wavelength in the range of 7-25 μm. While the proposed treatment methods provide therapeutic effects after several irradiation periods, complications such as tissue necrosis and edema are observed, which reduce the effectiveness of tissue metabolism, regeneration and enzymatic action, thereby reducing treatment efficiency. This is due to the fact that the shallow penetration of radiation cannot activate all the potential of tissue structure over the entire thickness. In addition, activation and optimization of intracellular actions does not equally affect different tissue types, different locations (deep or shallow) of the affected tissues, and different disease types. This increases the risk of recurrence and complications and slows down the tissue healing action because there is enough time for certain undesirable effects such as necrosis, keloid scars and tissue edema to occur.

Selective polarization laser mirrors with multilayer dielectric coatings applied on optical substrates are known (RU, C1, 2034318, April 27, 95). The laser mirror polarizes the radiation. However, since radiation is produced by other sources, its polarization parameters cannot be controlled by a given device.

A method of filtering optical radiation based on linear polarization of light is known (SU, C1, 1810868, April 23, 93). This method can block the long wave portion of radiation and continuously change the threshold passband frequency. However, it is not possible to linearly polarize specific wavelengths of radiation that vary depending on the task.

Apparatuses for the treatment of unwanted skin modifications that emit wave rays are known (US, A, 5320618, June 14, 94). However, the light wavelength converters used in these devices do not respond to changes in wavelength and cannot provide optimal therapeutic effects by combining certain wavelengths of radiation with waves of a certain magnitude.

High energy LEDs for photodynamic therapy are known (PCT, WO, A1, 93/21842, 1993). The apparatus and method proposed for activating the course of treatment by photodynamic therapy utilizes powerful LED radiation within certain selected portions of the optical spectrum. However, the complex feedback circuits required for optical variable monitoring make it impossible to adapt this device to certain types of disease.

Polarization diffraction gratings are known which polarize light at a broad frequency band of 1 to 100 μm (SU, C1, 1781659, 15.12.1992). However, this does not provide a change in the radiation parameters required to treat a particular type of disease because no wavelength selection within a predetermined band is observed.

Bioenergy therapy devices are known which consist of a pulse generator and an IR generator (RU, C1, 2043759, September 20, 95). However, this cannot directly adjust the light emitter to obtain the optimal therapeutic effect for a particular disease and provide the required combination of specific pulse parameters and specific radiation wavelengths.

Irradiation devices are known which pass various radiation doses through frequency selective partially transparent glass (DE, A1, 4129192, 1994). That is, the spectrum containing the (harmful) component of the vortex is first emitted and then corrected by a special device.

An irradiation apparatus is known in which the spectrum is separated by a spectral separator having a dichroic coating (DE, A1, 4112275, 1994). The device combines the length, polarization and modulation of the wave, thus providing no spectral distortion, but allowing the emission of spectra with predetermined characteristics.

Methods and apparatus are known for inducing tanning by pulsed rays (US, A, 5282842, February 1, 94). However, since this radiating device is not included in a circuit designed to vary the pulse cycle, the device itself cannot be adjusted for a particular type of disease.

Phototherapy systems based on LEDs emitting medium wavelength, narrowband non-interfering light are known (US, A, 5259380, 9 November 93). This LED is classified into diode banks which are regulated by a device for generating a potential difference and a device for forming a voltage having predetermined characteristics. However, the selection of the required radiation parameters is carried out by the whole system rather than through the use of the radiator properties.

Collinear therapy devices are known that provide therapeutic effects using IR rays with periodic pulses of controlled intensity (RU, C1, 2014854, June 30, 94). These radiations do not provide linear polarization and cannot guarantee the optimal combination of wavelength, modulation and polarization required for the treatment of a particular disease, but metal halide lamps with specific filling and controlling the intensity and spectral composition of the emitted light Is caused by.

Phototherapy devices, including light emitters and regulators, are closest to the proposed devices based on their engineering solutions (RU, C1, 2014854, September 20, 94 and RU, A1, 2033823, September 20, 95). . The radiator is calibrated according to the requirements for the flux flux emitted and the method of adjusting the flux parameters depends on the treatment program. However, adjustment to the flux parameters is ensured by changing the position of the radiator relative to the pathological focus or by changing the radiator itself, which hinders the selection of the optimal combination of radiation features to obtain the maximum therapeutic effect for a particular disease.

Inflammatory action, and methods of treating simple ulcers of the gastric and duodenal mucosa, are closest to the pathological tissue therapy proposed by the technical nature (RU, A1, 4707945, 26 November 1991). This suggests the possibility of treating the surface of the mucosa and the depth of the tracheal wall simultaneously with partial radiation inhalation by tissue located between the layers. However, the applied spectral band can be changed only by combining the power supplied to the emitter (eg, halogen lamp set) or by changing the distance from the endoscope end to the irradiated tissue surface. This method does not combine polarization and modulation with power and wavelength variations to achieve an optimal combination of radiation parameters for the treatment of specific diseases.

The present invention relates to a medicament and is designed to treat diseases involving metabolic disorders, enzymatic weakness, and regenerative dysfunction in diseased tissues. The method of treatment can be used for the treatment of rheumatism arthritis, vascular diseases of diabetes, gastric and duodenal ulcers, periodontitis and periodontitis and burns as well as pain relief after topical plastic surgery of the face. This may also apply to the treatment of other diseases of the same type.

1-Table of maximum and minimum therapeutic effects according to radiation type and medical indications for certain types of diseases.

2-Comparative feature of treatment results of periodontitis and periodontitis with radiation having A1, A, B, C, D characteristics.

Variant I-the rheological indicator values (RI),

Variant II-vascular peripheral resistance indicator value (IPR),

Variant III-Vascular Tension Indices (IVT).

3A- Comparative feature of treatment results of simple gastric and duodenal ulcer treatment with radiation having A1, A, B, C, D characteristics.

Variant I-the number of investigation periods when the symptoms of pain ceased (Nc-H),

Variant II-Number of irradiation periods when ulcers were restrained (Nk-H).

3B-Comparative feature of treatment results of chronic gastric and duodenal ulcer treatment by radiation with A1, A, B, C, D characteristics.

Variant I-the number of investigation periods when the symptoms of pain ceased (Nc-X),

Variant II-Number of irradiation periods when ulcers were restrained (Nk-X).

4-Comparative feature of the results of rheumatoid arthritis treatment with radiation having A1, A, B, C, D characteristics.

Deformation-indicator values of joint expansion elasticity and refractive elasticity.

5-Comparative feature of treatment results of diabetic vascular disease with radiation having A1, A, B, C, D characteristics.

Strain I-blood flow values (K) of limbs at radioactive densities of 50 and 300 mW / cm 2,

Variant II-skin temperature indicator (toσ) of the irradiated site at a radioactivity density of 50 to 300 mW / cm 2,

Variant III-Skin temperature index (tcT) of the foot at a radioactivity density of 50 to 300 mW / cm 2.

6- Comparative feature of treatment results after topical plastic surgery with radiation having A1, A, B, C, D characteristics.

Variant I-pulse blood volume value (PB),

Variant II-value of blood vessel wall resistance (VWR),

Variant III-Vascular Tension Indicator Value (IVT).

7- Comparative feature of burn treatment results with radiation having A1, A, B, C, D characteristics.

Variant I-the rheological indicator values (RI),

Variant II- vascular tension indicator value (IVT),

Variant III-Vascular Peripheral Resistance Indicator Value (IPR).

8-Placement of the device for treating pathological tissue with non-interfering radiation.

It is necessary to increase the treatment efficiency of various pathological conditions in several types of tissues (muscles, joints, blood vessels) characterized by the following disorders.

Metabolic disorders, especially in the rate of extraction of trace elements from blood circulating in tissues, reduction of inhalation and release of oxygen and glucose-containing components by the blood observed in blood disease symptoms in diabetes,

Metabolic disorders in articular cartilage in rheumatoid arthritis,

-Weakening of enzyme action and elevation of metabolic levels in vascular disease syndrome, burns, periodontitis and periodontitis, and gastric and duodenal ulcers,

-Disorders of the regenerative function of diseased tissues, for example in gastric and duodenal ulcers, tissue treatment during pain relief after local cosmetic surgery of the face, etc.

These disorders are accompanied by inflammatory action, tissue edema and necrosis.

These processes occur due to a number of major causes, namely, capillary circulation disorder, vascular circulation disorder, lymph flow disorder, blood flow slowing, slowing of oxidation and reducing action.

In the course of the diseases listed, these processes involve functional, anatomical and morphological changes in the components of all types of tissues.

These processes include local blood circulation as assessed by the following variables: blood flow level, pulsed blood volume, vascular wall resistance, vascular tension, rheology indicators, vascular peripheral resistance indicators, tissue elasticity, skin temperature, pain down time and tissue treatment time. Characterized by change.

The therapeutic effect is a combination to maximize the therapeutic effect for certain diseases caused by the aforementioned disorders, while polarizing and modulating the radiated flux, the non-interfering IR radiation in the wavelength range of 1 to 56 μm extended to the affected area. Is increased by irradiation. Exposure to non-interfering IR radiation simultaneously affects the entire tissue (surface and deep), effectively affecting the organs that control disease progression, while optimally optimizing the polarization and modulation effects of the radiated plus of a preset energy distribution. It suggests the possibility of combining. Optimal and maximum therapeutic effects for certain diseases are obtained by activating various actions in the tissue using radiation having the optimal combination of wavelength and power density.

The above useful results are provided by the proposed method of pathological tissue treatment using non-interfering radiation consisting of periodic IR irradiation in tissue for 1 to 20 minutes at 50 to 300 mW / cm 2 radiation density.

The investigation is typically repeated one or two days, depending on the time needed to stop the pain symptoms in the course of pathological tissue treatment.

The novelty of the method is the fact that a skin region located on top of the organ that controls disease progression resulting from disorders of metabolism, enzymes and regeneration is exposed to IR radiation in the 1 to 56 μm frequency band combined with linear polarization and time modulation. Is in. This method uses a set of different wavelengths within a preset range with linear polarization and time modulation applied to specific wavelengths depending on the nature of the disease. In addition, the radioactivity density is selected depending on the disease.

Therapeutic effects are produced by activation of metabolism, enzymes and regenerative actions in tissues.

All therapeutic effects result from increased blood circulation in the tissues and accelerated regeneration processes.

The treatment methods of the present invention include the functional action of all wave spectra with the optimal combination of radiological parameters for a particular type of disease. In all these cases, activation occurs throughout the diseased tissue as a result of the acceleration of metabolism, enzymes and regeneration. Significant improvements in medical indications in various diseases are achieved by the optimal combination of radiological parameters for shortening treatment duration and maximizing therapeutic effect.

The device of the present invention, designed for the treatment of pathological tissue with non-interfering radiation, provides a solution to the problem of optimizing the therapeutic effect for certain diseases. The device consists of a power source 1 and a radiation source comprising a regulator 2 and a radiator 3. When the electrical control signal is supplied from an additional power source of the controller, the device of the present invention provides a radiation variable that meets the requirements of the maximum therapeutic effect. The radiation source is precalibrated to provide the required radiation density.

The novelty of the device lies in the fact that a wideband semiconductor silicon light emitting diode (LED) is used as the emitter based on a supershallow p-n transition with wavelengths of non-interfering IR radiation in the range of 1 to 56 μm. The power supply 1 is connected along the p + n or n + p surface, providing current into the doped p + n or n + p region. The regulator 2 is equipped with additional field source leads (c, d, e) which are connected to the LEDs in such a way that the electric field acts along the n + p transition, providing an inverse / positive transition to the p + n transition. . The controller 2 adjusts the spectrum of the emission wavelength, the degree of linear polarization and the time modulation frequency. This regulator 2 regulates the LED by an electric field supplied from an additional power source via leads c, d and e. The electric field value is selected according to the nature of the disease.

To achieve the desired result, the device uses the effect of blocking a particular wavelength band of the broadband diode by the voltage applied to the p-n transition. When a regulated electric field is supplied, the radiation is linearly polarized. Another further regulating electric field modulates radiation with the required frequency.

Therefore, the apparatus combines radiation characteristics as required, such as a group of wavelengths within a predetermined range, the presence or absence of linear polarization, for example, radiation modulation with a preset frequency of 200 or 30 Hz. The above description optimizes the therapeutic effect depending on the nature of the disease.

Thus, the device of the present invention realizes the treatment method described above and provides the optimum therapeutic effect depending on the nature of the disease.

As a result, the present invention can achieve the maximum therapeutic effect depending on the nature of the disease.

Diseases caused by metabolic, enzyme and regenerative dysfunction have resulted in functional, anatomical and morphological changes in tissue structural elements causing disease in tissues. Treatment methods for the following pathologies are as follows.

Periodontitis and periodontitis resulted in pathological changes such as tissue necrosis, capillary circulatory disorders of gingival muscle tissue, edema, and progression of inflammation in the tissue. The flesh is characterized by oral bleeding, hypersensitivity, hygiene indicators (IH), rheology indicators (RI), vascular peripheral resistance indicators (IPR), and vascular tension indicators (IVT). Radiation with one group of wavelengths ranging from 1 to 56 μm in combination with polarization and 30 or 200 Hz modulation produced the maximum therapeutic effect. (See Figures 1 and 2).

The effect is characterized by stable RI-v.1, IPR-v.II and IVT-v.III, these values being close to the standard (see FIG. 2). Even in the minimal therapeutic effects produced by unpolarized and unmodulated radiation of 1 to 56 μm, the values of RI, IPR, and IVT are closer to the standard than those produced by radiation having a wavelength of 7 to 25 μm (FIG. 2, See A1). This effect resulted from stimulation of blood circulation and an increase in oxygen bearing blood.

Gastric and duodenal ulcers are secondary to inflammation of the mucous membranes in the tissues, formation of keloid scars as a result of the treatment of ulcers, drying of the epithelial tissues leading to necrosis of the mucosal tissues, and an unfriendly combination of applied radiation variables that delay tissue treatment. Caused pathological changes such as inflammation. Thus, for example, mucosal surface epithelium is well treated after irradiation for a short time by radiation with high frequency modulation (200 Hz) without increasing power density (see FIGS. 1, 3A, 3B). Epithelial tissue of the inner mucosal layer was effectively treated when exposed to prolonged periods at increased light flux power. This treatment is characterized by deep penetration of energy into mucosal tissue (see FIGS. 1, 3A, 3B), high levels of radiation absorption by tissue, and good energy distribution across tissues. The effectiveness of this action was assessed by the number of irradiation periods required for stopping pain symptoms and restraining ulcers. The maximum therapeutic effect of a simple ulcer was irradiated with radiation of 1 to 56 μm frequency band combined with polarization (see FIG. 3A, vI, v.II B) at a radiation density of 50 mW / cm 2 or at polarization and at 200 Hz frequency. Observed when irradiated with radiation of 1 to 56 μm frequency band in combination with modulation (FIG. 1, vI, vII C, FIG. 3A). The maximum therapeutic effect on chronic ulcers was observed when irradiated with radiation in the 1-56 μm frequency band combined with polarization and 30 Hz frequency modulation. Judging from the above, the minimal therapeutic effect in all cases is characterized by better results than those produced by radiation of 7 to 25 μm, requiring 3-4 times less irradiation to stop pain symptoms and restrain ulcers. . This therapeutic effect is increased by optimally distributing energy across epithelial tissue, which prevents overheating of the tissue during irradiation.

Rheumatoid arthritis caused local primary venous circulation disorder, hypoxia of joint elements, metabolic disorders of articular cartilage, aseptic necrosis of the head of the joint, idiopathic aseptic necrosis. The joint state is: a) extremely extended position (B), original joint position (E), extended elasticity at position (C) corresponding to zero degree angle after expansion, b) extremely curved position (A) , Flexural elasticity at the original joint position (F), position (D) corresponding to a zero degree angle after bending. The maximum therapeutic effect is characterized by minimum residual effort in flexion and expansion, and maximum flexion and expansion angle (FIG. 1). The maximum therapeutic effect was generated by irradiating the joint at a power density of 50 mW / cm 2 with radiation of 1 to 56 μm frequency band combined with polarization and 200 and 30 Hz frequency modulation. Minimal therapeutic effects occurred at 3-4 times earlier irradiation than at irradiation with 7-25 μm to stop pain symptoms and normalize biased capillary pressure.

Vascular disease in diabetes has resulted in a decrease in ultra trace elements, stabilization of tissues, a decrease in the uptake of oxygen and oxygen-bearing elements in the blood, and a decrease in hormone production as well as metabolic functions. Localization and suppression of these effects by irradiation is characterized by an increase in the skin temperature of the irradiated site and foot, depending on changes in cell membrane permeability that affect intercellular energy exchange, its enzyme and regenerative activity, and hormone production. The maximum therapeutic effect is produced by radiation of 1 to 56 μm frequency band, polarized at a power density of 50 mW / cm 2 or modulated to a power density of 300 mW / cm 2 (FIGS. 1, 5). Minimal therapeutic effects resulted in surpassing the effectiveness of treatment with radiation of 1-25 μm frequency bands (FIG. 5, A1). The results were confirmed in patients demonstrating a nearly normal drop in body temperature, demonstrating that muscle and joint pain, muscle tension, and limitations of motion decrease very quickly. The effect produced was caused by enhanced blood circulation. This represents a significant stimulus of tissue exchange levels, peroxide oxidation, especially since the amount of blood circulation per minute before treatment correlates with glucose and immune reactive insulin levels in the blood.

Temporal pain relief after topical plastic surgery of the face caused undesirable pathological changes: mechanical wounds of the tissue by surgery, sterile inflammation of the tissue, edema of soft tissue, keloid scar formation of connective tissue. These changes were assessed by the degree of change in local circulation, manifested as a decrease in vibratory blood volume (PB) and vascular wall resistance (VWP) serving as blood circulatory indicators. In addition, these changes are characterized by the presence of indicators of low vascular tension (IVT) and the presence of edema. The maximum therapeutic effect is caused by radiation of 1 to 56 μm frequency bands combined with polarization and 200 or 30 Hz frequency modulation depending on the particular indication (FIGS. 1, 6, C, D). Minimal therapeutic effects result in these signs closer to the standard for patients treated with radiation of 1-25 μm frequency bands due to good circulatory and skin cell regeneration (FIG. 6, A1). Positive therapeutic kinetics have been observed to reduce pain and edema as a result of only one irradiation. After the entire course of treatment, the wound healed as originally intended without purulent or suture separation.

Burns caused inflammatory progression of wounds, vascular disorders due to capillary dilator and blood circulation slowing, edema and hypertrophic granulation of tissue, and necrosis. These progressions are characterized by elevations of the rheology index (RI), the vascular tension index (IVT), and the vascular peripheral resistance index (IPR). The maximum therapeutic effect was produced with radiation of 1 to 56 μm frequency bands combined with polarization and 200 or 30 Hz frequency modulation depending on the particular indication (FIGS. 1, 7). Minimal therapeutic effects were obtained closer to the standard than those obtained with radiation of 1-25 μm frequency (FIG. 7, A1). Visual observation was able to identify faster scar healing and resolution of edema as well as smaller scar deformations at the edges of the implanted skin tissue.

The treatment method of the present invention was tested in a group of 60 patients each. These groups formed by age. Control groups consisting of simple or chronic patients were divided into subgroups according to age (16 to 68 years) regardless of gender. All control variables were measured when the pain relief period or pain symptoms were stopped. Organs involved in the course of the disease were examined for 20 minutes for 1 or 2 days, depending on the condition of the patient. The measurements were taken after 10 irradiation periods. The number of irradiation periods required to reach the effect when pain signs ceased or ulcers were restrained was recorded. Therapeutic radiation was directed directly to the skin area located above the organs or joints involved in the course of the disease. The surface area of the irradiated sites was chosen to provide three power density controls, for example 50, 150, 300 mW / cm 2. Control measurements were made before and after treatment. Patients in the control group were irradiated with radiation from the 7-25 μm frequency band and the same variables characterizing treatment efficiency were recorded. The light source of the emitter was calibrated to select an appropriate distance between the LED and the tracheal surface associated with disease progression. This was due to the different degree of IR absorption depending on the combination of specific wavelengths in the 1 to 56 μm band.

Semiconductor LEDs have evolved in the raw IR spectrum by forming a correlation gap in the density of the electronic states, or degenerate hole gases generated in bulk doped quantum-sized doping profiles (for example, IR-emission on this topic). Induced in Silicon by Heavily Doped Quantum-Size Diffusion Profiles. ", Known in 1993. The degree of failure in the size of the correlation gap and its distribution within the doped region of the pn transition regulated the characteristics of the radiation.

This device provided different combinations of spinning features. All medical control measurements were performed after irradiation.

Radiation parameter combinations for all groups of patients were done similarly as follows.

A1-radiation of the band of 7 to 25 μm,

A-radiation of 1 to 56 μm frequency band,

B-radiation of 1 to 56 μm frequency band in combination with linear polarization,

C-radiation of 1 to 56 μm frequency band, combined with linear polarization and modulation at 200 Hz,

D-radiation of 1 to 56 μm frequency band combined with linear polarization and modulation at 30 Hz.

The method of treating pathological tissue via non-interfering radiation can be applied as follows.

Example 1 Groups of patients aged 30 to 57 years diagnosed as periodontitis and periodontitis were irradiated with radiation of 1-56 μm frequency band combined with linear polarization and modulation at 200 and 30 Hz. After five investigation periods, all medical signs typical of the disease normalized to a baseline deviation of less than 1% and the edema and bleeding were resolved. This treatment was monitored visually and by rheometry as shown in FIG. 2.

Example 2 A group of 27-66 year old patients diagnosed with gastric and duodenal ulcers were irradiated with radiation of 1-56 μm frequency in combination with linear polarization and modulation at 200 and 30 Hz. After three investigation periods, normalization of major medical signs was observed. Pain signs stopped after one irradiation period, while ulcers were arrested after three to five irradiation periods. No secondary inflammation progression or tissue edema occurred. This treatment was monitored by using an endoscopic method and by asking the patient (see FIGS. 3A, 3B).

Example 3 A group of patients aged 35 to 68 years diagnosed with rheumatoid arthritis was irradiated with radiation of 1 to 56 μm frequency combined with linear polarization and modulation at 200 and 30 Hz. After ten irradiation periods, the elastic and intra-articular internal friction levels of the joint tissues returned to normal, pain signs stopped, and capillary pressure recovered. This treatment was monitored using the Percutaneous Electrolytic Response Assay and Epidemiologic Diagnostics (see FIG. 4).

Example 4 Groups of 17-53 year olds diagnosed with vascular disease of diabetes were irradiated with radiation of 1-56 μm frequency band combined with linear polarization and modulation at 200 and 30 Hz. After seven irradiation periods, a significant improvement in limb blood flow rate was observed with an optimum and a deviation within 2%. The skin temperature of the irradiated area and the foot lowered to normal. Muscle and joint pain subsided, muscle tension normalized, and joint flexibility increased. This treatment was monitored by calculations by Tishenko method and by rheometry. Subjective signs were monitored by asking the patient (see FIG. 5).

Example 5 A group of 18 to 48 year old patients in the pain relief phase after local cosmetic surgery of the face was irradiated with radiation of 1 to 56 μm frequency combined with linear polarization and modulation at 200 and 30 Hz. After ten irradiation periods, medical signs of pulsed blood volume and vascular wall resistance and vascular tension indices were normalized. Soft tissue edema was also resolved. This treatment was monitored by rheology of the facial aorta (see FIG. 6).

Example 6 A 16 to 40 year old patient group of first and second degree burns of the face and neck was irradiated with radiation of 1-56 μm frequency band combined with linear polarization and modulation at 200 and 30 Hz. After 10 investigation periods, the medical signs, such as the rheology index, vascular tension index, and vascular peripheral resistance index, were normalized. Skin implanted for autologous formation showed a decrease in tissue age necrosis and hypertrophic granulation as well as convergent keloid scar progression (see FIG. 7). This treatment was monitored either by naked eye or by measurement of the rheology of intact skin 1-3 mm away from the burn site.

The treatment method is best realized in the following manner of operation of the device of the invention.

When the current stabilized power source 1 was connected to the device, current began to flow through the P + (n +) region of the radiator 3. The (p-n) transition emitted light rays in the 7-25 μm spectral range. The voltage from one of the additional power sources was supplied to the controller 2 via terminal b and extended the spectral range from 1 to 56 μm. The voltage supplied between terminals c at the p-n transition has converted the unpolarized radiation of the p-n transition into linear polarized radiation which preserves other radiation characteristics. The voltage supplied between terminals (d) converted the unmodulated (persistent) radiation of the p-n transition into 200 Hz modulated radiation which preserved other radiation characteristics. The voltage supplied between the terminals (e) converted the unmodulated (persistent) radiation of the p-n transition into a 30 Hz modulated radiation that preserved other radiation characteristics.

Thus, the device of the present invention has radiated radiation that provides an optimal treatment for all types of diseases caused by metabolic, enzyme and regenerative dysfunction.

Claims (5)

Irradiation is carried out periodically for 1 to 20 minutes with IR radiation having a radioactive density of 50 to 300 mW / cm 2, which is directed to the upper skin area of the organ involved in the path of disease caused by tissue metabolism, enzymes and regeneration impairment. A method for treating pathological tissue by non-interfering radiation, which is done directly and by radiation in the wavelength range of 1 to 56 μm with linear polarization and time modulation. The method of claim 1, wherein the introduction of linear polarization and time modulation of wavelengths and radiation within a predetermined range is selected according to the nature of the disease. The method of claim 1, wherein the radioactivity density is selected according to the nature of the disease. Extremely shallow, consisting of a power source 1 and a radiation source comprising a regulator 2 and a radiator 3 precalibrated to provide the required radiation density, and having an uninterfering IR radiation wavelength in the range of 1 to 56 μm. A broadband semiconductor silicon light emitting diode (LED) based on a (supershallow) pn transition is used as the emitter (3), and if the power source (1) is a p + n or n + p transition (a) it is connected and doped p Provides current in the + n or n + p region and, to the regulator 2, the electric field is applied along the p + n transition (a) to provide a reverse and forward movement in the p + n transition. Pathological tissue by non-interfering radiation, equipped with conducting wires (c, d, e) for additional sources of connected electric fields, in which the regulator (2) adjusts the spectral range of the radiation wavelength, the degree of linear polarization and the frequency of time modulation. Device for the method of treatment. 5. Device according to claim 4, wherein the regulator (2) regulates the LED by an electric field supplied from an additional power source via conductors (c, d, e) with an electric field value selected according to the nature of the disease.